KURODA Yoshihiro 黒田義弘

Researcher Number	90093236
Other IDs
Affiliation (based on the past Project Information) *help	2016: 姫路獨協大学, 薬学部, 特別教授 2010 – 2015: 姫路獨協大学, 薬学部, 教授 2007: Himeji Dokkyo University, Faculty of Pharmaceutical Sciences, Professor 2006: 京都大学, 薬学研究科, 助教授 1997 – 2004: 京都大学, 薬学研究科, 助教授 … More 1999: 京都大学, 大学院・薬学研究科, 助教授 1987 – 1988: 京都大学, 薬学部, 助手 1986: 京大, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Physical pharmacy / Biological pharmacy Except Principal Investigator Physical pharmacy / Periodontology / Periodontal dentistry
Keywords	Principal Investigator oligopeptide / オリゴペプチド / EGFR / NYQQN / KIYEK / KIFMK / CDスペクトル / ジブカイン / 局所麻酔薬 / Tetracaine … More / Local Anesthetic / Spin Diffusion / Lipid Bilayer Vesicles / Nuclear Overhauser Effect / Window Function / Two-dimensional NMR / 関数処理 / 膜の運動性 / フォスファチジルコリン / サインベル関数 / ウィンドウ関数 / ベシクル / リン脂質 / 核オーバーハウザー効果 / 二次元NMR / テトラカイン / psuedosubstrate / docking simulation / ATP-non・competitive inhibitor / autophosphorylation / epidermal growth factor receptor / 擬似基質 / 阻害剤 / 疑似基質 / ドッキングシミュレーション / ATP非競合阻害剤 / 自己リン酸化 / 上皮増殖因子受容体 / dephosphorylation / suppression of phosphorylation / insulin receptor / lidocaine / local anesthetics / 脱リン酸化 / リン酸化抑制 / インスリン受容体 / リドカイン / 局所麻酔剤 / CD spectra / amyloid / β sheet / α helix / Parkinson's disease / Prion disease / Altzheimer disease / アミロイド線維 / βシート / αヘリックス / パーキンソン病 / プリオン病 / アルツハイマー病 / CD spectrum / NMR spectrum / Interaction / Dibucaine / Local anesthetics / Peptide / Inactivation gate / Sodium channel / リポソーム / フォスファチジルセリン / ミセル / NMRスペクトル / 相互作用 / ペプチド / 不活性化ゲート / ナトリウムチャンネル / カスパーゼ3活性 / 細胞毒性 / 細胞増殖 / ATP非競合的作用機序 / 阻害ペプチド / IGF1R / チロシンキナーゼ / 細胞膜透過性 / EGFR, IGF1R, 阻害ペプチド … More Except Principal Investigator apo A-1 / 歯周病 / 歯肉上皮細胞 / Monte Carlo-cal / any loid / low density lipo-protein / high performance fromtall Analysis / Highly fine structure / Biosuper molecular Assembly / SPR / シミュレーション / アルツハイマー / レセプター / 血漿アポリポタンパク質 / 脂質2分子層 / 低密度血漿リポタンパク質 / 表面プラスモン共鳴 / apoA-1 / 表面ブラズモン共鳴 / モンテカルロ計算 / アミロイド / 低密度リポタンパク質 / 高性能先端分析法 / 高次微細構造 / 生体超分子集合体 / 表面プラズモン共鳴 / capillary electrophoresis / prion protein / sodium channel inactivation gate peptide / ESI-T0F-MS / high-performance frontal analysis / microheterogeneity / plasma protein binding / glycochain / プリオン蛋白 / Naチャンネル蛋白 / 電子スプレー型飛行時間質量分析 / 高速先端分析法 / 糖鎖ミクロ不均一性 / 薬物・タンパク結合解析 / 糖タンパク質糖鎖 / 抗菌ペプチド / 歯周病細菌 / P.gingivalis / ＩＬ－２２ / 細胞内侵入細菌 / IL-22 / ＡＰＲＩＬ / ＢＡＦＦ / CCL22 / CCL17 / 歯肉線維芽細胞 / EGFR Less

Effect of IL-22 on immune response against periodontal bacteria
- Principal Investigator
  
  Kato-kogoe Nahoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Osaka Medical College
  Hyogo Medical University
The effect of EGF receptor pathway on cytokine production in gingival fibroblasts
- Principal Investigator
  
  KOGOE Nahoko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Himeji Dokkyo University
The inhibitory potency of peptides derived from autophosphorylation sites of receptor tyrosine kinase in a non-ATP-competitive mechanism on tumor cells.Principal Investigator
- Principal Investigator
  
  KURODA Yoshihiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Himeji Dokkyo University
Studies on inhibitors for epidermal growth factor receptor based on oligopeptides which imitated pseudosubstratesPrincipal Investigator
- Principal Investigator
  
  KURODA Yoshihiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Himeji Dokkyo University
  Kyoto University
Mechanisms of suppression of insulin signaling by Na channel blockersPrincipal Investigator
- Principal Investigator
  
  KURODA Yoshihiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Structural investigations for developing the rapeutics of Altzheimer, prion, and Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  KURODA Yoshihiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
医薬品化学領域における生体超分子集合体の高次微細構造と機能に関する研究
- Principal Investigator
  
  TAGA Tooru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Development of fine micro analytical method of drug recognition function of sugar chains
- Principal Investigator
  
  NAKAGAWA Terumichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Structural investiga tions for developing therapeutics of functional disorders due to the sodium channelPrincipal Investigator
- Principal Investigator
  
  KURODA Yoshihiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Two-dimensional nuclear magnetic resonance spectroscopic studies on the interactions between membranes and drugsPrincipal Investigator
- Principal Investigator
  
  KURODA Yoshihiro
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University

All 2015 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells.2015
- Author(s)
  Kuroda Y, Kato-Kogoe N, Tasaki E, Yuasa-Sunagawa M, Yamanegi K, Nakasyo K, Nakase I, Futaki S, Tohyama Y, Hirose M
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 765 Pages: 24-33
- DOI
  10.1016/j.ejphar.2015.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460405, KAKENHI-PROJECT-26463151
[Journal Article] Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells.2013
- Author(s)
  Kuroda Y, Kato-Kogoe N, Tasaki E, Murata E, Ueda K, Abe M, Miyamoto K, Nakase I, Futaki S, Tohyama Y, Hirose M.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 5 Pages: 87-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590076
[Journal Article] Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells.2013
- Author(s)
  Kuroda Y, Kato-Kogoe N, Tasaki E, Murata M, Ueda K, Abe M, Miyamoto K, Nakase I, Futaki S, Tohyama Y, Hirose M
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 698 Issue: 1-3 Pages: 87-94
- DOI
  10.1016/j.ejphar.2012.10.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390297, KAKENHI-PROJECT-22590076, KAKENHI-PROJECT-23590374, KAKENHI-PROJECT-23593077, KAKENHI-PROJECT-23700588, KAKENHI-PROJECT-23790129
[Journal Article] Effects of TrkA inhibitory peptide on cancer-induced pain in a mouse melanoma model.2012
- Author(s)
  Tabata M, Murata E, Ueda K, Kato-Kogoe N, Kuroda Y, Hirose M.
- Journal Title
  
  J Anesth.
  
  Volume: in press
- NAID
  10031070301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23593077
[Presentation] IGF-1Rの自己リン酸化部位由来ペプチドがMCF-7ヒト乳がん細胞に及ぼす影響2013
- Author(s)
  黒田義弘,小越菜保子,田崎絵美,中瀬生彦,二木史朗,通山由美,廣瀬宗孝
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-23593077
[Presentation] 細胞透過性オリゴペプチドによるA549ヒト肺線がん細胞に体する細胞増殖抑制、細胞毒性、及びアポトーシスへの影響2011
- Author(s)
  黒田義弘、村田恵理、上田康陽、田崎絵美、小越菜保子、阿部峰大、宮本和英、中瀬生彦、二木史朗、通山由美、廣瀬宗孝
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22590076
[Presentation] EGFRの自己リン酸化部位由来ペプチドのA549ヒト肺腺がん細胞における効果2011
- Author(s)
  黒田義弘,村田恵理,上田康陽,田崎絵美,小越菜保子,阿部峰大,宮本和英,中瀬生彦,二木史朗,通山由美,廣瀬宗孝
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23593077
[Presentation] 細胞透過性オリゴペプチドによるA549ヒト肺腺がん細胞に対する細胞増殖抑制、細胞毒性、及びアポトーシスへの影響2011
- Author(s)
  黒田義弘
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡(静岡市)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22590076
[Presentation] EGFRの自己リン酸化部位由来ペプチドの A549ヒト肺腺がん細胞における効果2011
- Author(s)
  黒田義弘，村田恵理，上田康陽，田崎絵美，小越菜保子，阿部峰大，宮本和英，中瀬生彦，二木史朗，通山由美，廣瀬宗孝
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-23593077
[Presentation] EGFRの自己リン酸化部位由来ペプチドのA549ヒト肺腺がん細胞における効果2011
- Author(s)
  黒田義弘
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22590076
[Presentation] EGFRの自己リン酸化部位由来ペプチドのA549ヒト肺腺がん細胞における効果.2011
- Author(s)
  黒田義弘、村田恵理、上田康陽、田崎絵美、小越菜保子、阿部峰大、宮本和英、中瀬生彦、二木史朗、通山由美、廣瀬宗孝
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22590076
[Presentation] IGF-1Rの自己リン酸化部位由来ペプチドがMCF-7ヒト乳がん細胞に及ぼす影響
- Author(s)
  黒田義弘
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23593077

1. KOGOE Nahoko (60509115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. NAKAGAWA Terumichi (70025708)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. OHYAMA Hideki (90280685)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIBUKAWA Akimasa (30170913)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAGA Tooru (00025694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HONDA Tetsuro (00025719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MATSUMOTO Osamu (10231599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中山真彰 (10579105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山根木康嗣 (00434944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山田直子 (10319858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 通山由美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 廣瀬宗孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KURODA Yoshihiro 黒田 義弘

Research Projects

Research Products

Co-Researchers

Effect of IL-22 on immune response against periodontal bacteria

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of EGF receptor pathway on cytokine production in gingival fibroblasts

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The inhibitory potency of peptides derived from autophosphorylation sites of receptor tyrosine kinase in a non-ATP-competitive mechanism on tumor cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on inhibitors for epidermal growth factor receptor based on oligopeptides which imitated pseudosubstratesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of suppression of insulin signaling by Na channel blockersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural investigations for developing the rapeutics of Altzheimer, prion, and Parkinson's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

医薬品化学領域における生体超分子集合体の高次微細構造と機能に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of fine micro analytical method of drug recognition function of sugar chains

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural investiga tions for developing therapeutics of functional disorders due to the sodium channelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Two-dimensional nuclear magnetic resonance spectroscopic studies on the interactions between membranes and drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells.2013

Author(s)

Journal Title

Data Source

[Journal Article] Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of TrkA inhibitory peptide on cancer-induced pain in a mouse melanoma model.2012

Author(s)

KURODA Yoshihiro 黒田義弘