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IKEHARA Susumu  池原 進

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IKEHARA Susuu  池原 進

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Researcher Number 90108986
Affiliation (based on the past Project Information) *help 2017: 関西医科大学, 医学部, 教授
2016: 関西医科大学, 医学部, 共同研究講座(大塚製薬株式会社)幹細胞異
2014 – 2015: 関西医科大学, 医学部, 教授
1997 – 2005: 関西医科大学, 医学部, 教授
1987 – 1995: 関西医科大学, 医学部, 教授
1986: 関西医科大学, 教授
Review Section/Research Field
Principal Investigator
Experimental pathology / Biological Sciences
Except Principal Investigator
Nerve anatomy/Neuropathology / Hematology / Cerebral neurosurgery / Orthopaedic surgery / Experimental pathology / Biological Sciences / Urology
Keywords
Principal Investigator
造血幹細胞 / 骨髄移植 / ストローマ細胞 / 間葉系幹細胞 / 臓器移植 / 免疫学的寛容 / bone marrow transplantation / 自己免疫疾患 / 骨髄内骨髄移植 / モンキー … More / 多能性造血幹細胞 / 主要組織適合抗原複合体 / hemopoietic stem cell / mesenchymal stem cell / organ transplantation / 灌流法 / マウス / 門脈 / Stromal cell / 胸腺リンパ腫 / Animal Models / Autoimmune Diseases / Bone Marrow Transplantation / 白血病 / 血小板減少性紫斑病 / Natural Suppressar Cell / 骨移植 / regeneration medicne / 再生医学 / カニクイザル / 難病 / 再生医療 / monkey / mouse / intractable disease / auotimmune disease / 糖尿病 / 臟器移植 / 免疫寛容 / animal models / portal vein tolerance / chr glomerulonephritis / diabetes mellitus / stromal cells / hemopoietic stem cells / autoimmune diseases / 胸腺異常 / モデルマウス / 慢性関節リウマチ / インスリン非依存性糠尿病 / T細胞分化 / 免疫血小板減少症 / 慢性腎炎 / インスリン依存型糖尿病 / インスリン非依存型糖尿病 / 骨髄微小環境 / モデル動物 / Retrovirus / AKR mouse / Thymic lymphoma / Bone marrow transplantation / サイトカイン / 主要組織適合抗原複合体(MHC) / MHC class IKO mouse / H-2 congenic mouse / Cobblestone colony / CFU-S / Major histocompatibility complex / Pluripotent hemopoietic stem cell / c-kit / 主要組織適合抗原 / lprマウス / MRL / stem cell disorder / immunological tolerance / stromal cell / pluripotent hemopoietic stem cell / 自己免疫マウス / SCIDマウス / ヌードマウス / 胸腺 / 液性因子 / 抗腫瘍作用 / natural suppressor cell / 抑制因子 / 抗腫瘍性 / natural suppressor cells … More
Except Principal Investigator
flow cytometry / bone marrow / differentiation / transplantation / stem cell / fludarabine phosphate / 造血幹細胞 / 骨髄移植 / 免疫系 / 生体分子 / 細胞・組織 / 免疫学 / 病理学 / 脳神経疾患 / グリオーシス / 軸索変性 / 嗅球 / 鼻粘膜 / 細胞間相互作用 / マクロファージ / サイトカイン / ケモカイン / 神経変性 / 炎症 / 免疫 / 脳 / 脈絡叢 / 髄膜 / xenotransplantation / hematopoietic stem cell / フローサイトメトリー / 異種間移植 / f regeneration / ischemic brain / Regeneration / regeneration / bone marroew / leg-transplantation / IBM-BMT / Fludarabine phosphate / トレランス / 下肢移植 / 同種肢移植 / 骨髄内骨髄移植 / 胸腺細胞の分化 / T細胞抗原レセプター(TcR)再構成 / T細胞膜分化抗原 / 白血病ウィルス / T細胞白血病 / 胸腺腫 / T細胞 / 再生 / 胸腺 / Intra-bone marrow injection(IBMI)法 / CXCR4 / SDF-1 / トランスレーショナルリサーチ / Intra-bone marrow injection (IBMI)法 / 再生医療 / 可塑性 / 臍帯血移植 / モンキー / 免疫寛容 / 腎移植 Less
  • Research Projects

    (24 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (35 People)
  •  Treatment of cancer by a new BMT method using co-transplantation of regenerated thymus

    • Principal Investigator
      HOSAKA Naoki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Kansai Medical University
  •  Histological architecture of the leptomeninges and choroid plexus underlying brain-immune cell-cell interactions and its relevance to health and disease

    • Principal Investigator
      Shimada Atsuyoshi
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kyorin University
      Institute for Developmental Research, Aichi Human Service Center
  •  A challenge for long-term human lymphohemopoietic reconstitution in mice with normal immunity

    • Principal Investigator
      KIMURA Takafumi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  骨髄腔内直接移植法を用いる体性あるいは胚性幹細胞の可塑性の解明

    • Principal Investigator
      SONODA Yoshiaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kansai Medical University
      Kyoto Prefectural University of Medicine
  •  Study for neuronal regeneration in ischemic brain using bone marrow transplantation

    • Principal Investigator
      KAWAMOTO Keiji
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kansai Medical University
  •  A New Bone Marrow Transplantation Method the Treatment of Intractable DiseasesPrincipal Investigator

    • Principal Investigator
      IKEHARA Susumu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Kansai Medical University
  •  新しい骨髄移植方法を用いた造血並びに臓器再生機構の解析-マウスとモンキーを用いて-Principal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kansai Medical University
  •  Allogeneic Leg Transplantation With A New Method For Bone Marrow Transplantation

    • Principal Investigator
      NAKAMURA Masaya
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kansai Medical University
  •  多能性造血幹細胞とストローマ細胞間の主要組織適合抗原複合体拘束性の解析Principal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kansai Medical University
  •  モンキーを用いた新しい骨髄移植方法の開発Principal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Kansai Medical University
  •  モンキー同種腎移植における経門脈骨髄移植併用の有用性に関する研究

    • Principal Investigator
      川喜田 睦司
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Kansai Medical University
  •  多能性造血幹細胞の血球初期分化-マウス,モンキー,ヒトでの解析-Principal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kansai Medical University
  •  New Strategies for Bone Marrow Transplantation and Organ TranplantationPrincipal Investigator

    • Principal Investigator
      IKEHARA Susuu
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Kansai Medical University
  •  多能性造血幹細胞とストローマ細胞との間の主要組織適合抗原複合体拘束性の解析Principal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kansai Medical University
  •  多能性造血幹細胞とストローマ細胞との間の主要組織適合抗原複合体拘束性の解析Principal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kansai Medical University
  •  多能性造血幹細胞から血球への初期分化解析Principal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kansai Medical University
  •  新しい多能性造血幹細胞の精製法の確立と初期分化の解析Principal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kansai Medical University
  •  多能性造血幹細胞の免疫担当細胞(主としてT細胞)への分化機構ー正常と異常での解析ーPrincipal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kansai Medical University
  •  Basic studies on bone marrow transplantationPrincipal Investigator

    • Principal Investigator
      IKEHARA Susumu
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Kansai Medical University
  •  “G_1期造血幹細胞"の分泌する細胞増殖抑制因子の精製と作用機序の解析Principal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kansai Medical University
  •  “G_1期造血幹細胞"の分泌する細胞増殖抑制因子の精製とその作用機序の解析Principal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kansai Medical University
  •  “造血幹細胞異常症"の病因の解析と骨髄移殖による治療の為の基礎的研究Principal Investigator

    • Principal Investigator
      IKEHARA Susumu
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Kansai Medical University
  •  同種骨髄移植後に発生する供与者由来胸腺型白血病(リンパ腫)の発症機序の解析Principal Investigator

    • Principal Investigator
      池原 進
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kansai Medical University
  •  骨髄移植AKRマウスに発生する異系マウス骨髄由来の胸腺腫、白血病の研究

    • Principal Investigator
      小野江 和則
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University

All 2015 2014 2013 2012 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] Increased recruitment of bone marrow-derived cells into the brain associated with altered brain cytokine profile in senescence-accelerated mice2015

    • Author(s)
      Hasegawa-Ishii S, Inaba M, Li M, Shi M, Umegaki H, Ikehara S and Shimada A
    • Journal Title

      Brain Structure and Function

      Volume: 未定 Issue: 3 Pages: 1513-1531

    • DOI

      10.1007/s00429-014-0987-2

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25290020, KAKENHI-PROJECT-26430061
  • [Journal Article] Dynamics of bone marrow-derived cells relevant to the brain-immune cell-cell interactions under non-inflammatory conditions2014

    • Author(s)
      Hasegawa-Ishii S, Inaba M, Li M, Umegaki H, Ikehara S and Shimada A
    • Journal Title

      Current Trends in Neurology

      Volume: 8 Pages: 39-52

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25290020
  • [Journal Article] Selective localization of bone marrow-derived ramified cells in the brain adjacent to the attachments of choroid plexus.2012

    • Author(s)
      Hasegawa-Ishii S, Shimada A, Inaba M, Li M, Shi M, Kawamura N, Takei S, Chiba Y, Hosokawa M, Ikehara S.
    • Journal Title

      Brain Behav Immun.

      Volume: 29 Pages: 82-97

    • DOI

      10.1016/j.bbi.2012.12.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J40278, KAKENHI-PROJECT-24650190, KAKENHI-PROJECT-24791932, KAKENHI-PROJECT-25290020, KAKENHI-PROJECT-23500436
  • [Journal Article] Proliferative and migratory potentials of human cord blood-derived CD34^- severe combined immunodeficiency repopulating cells that retain secondary reconstituting capacity.2004

    • Author(s)
      Kimura T, Wang J, Matsui K, Imai S, Yokoyama S, Nishikawa M, Ikehara S, Sonoda Y.
    • Journal Title

      Int.J.Hematol. 79

      Pages: 328-333

    • NAID

      10013081994

    • Data Source
      KAKENHI-PROJECT-16590957
  • [Journal Article] Proliferative and migratory potentials of human cord blood-derived CD34-negative SCID-repopulating cells that retain secondary reconstituting capacity2004

    • Author(s)
      Kimura T, Wang J, Matsui K, Imai S, Yokoyama S, Ikehara S, Sonoda Y
    • Journal Title

      Int J Hematol 79

      Pages: 328-333

    • Data Source
      KAKENHI-PROJECT-15039227
  • [Journal Article] SCID-repopulating cell activity of human cord blood-derived CD34^- cells assured by intra-bone marrow injection2003

    • Author(s)
      Wang J, Kimura T, Asada R, Hrada S, Ikehara S, Sonoda Y, et al.
    • Journal Title

      Blood 101(8)

      Pages: 2924-2931

    • Data Source
      KAKENHI-PROJECT-15039227
  • [Presentation] Dynamics of bone marrow-derived cells relevant to the brain-immune cell-cell interactions under non-inflammatory conditions (脳と免疫系の細胞間相互作用における骨髄由来細胞の動態と分化)2015

    • Author(s)
      Shimada A, Hasegawa-Ishii S, Inaba M, Li M, Umegaki H and Ikehara S
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸市
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-25290020
  • [Presentation] Cytokine-mediated increase of bone marrow cell recruitment into the brain in neurodegeneration2015

    • Author(s)
      Hasegawa-Ishii S, Inaba M, Li M, Umegaki H, Ikehara S and Shimada A
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋市
    • Year and Date
      2015-04-30
    • Data Source
      KAKENHI-PROJECT-25290020
  • [Presentation] Changes in profiles of brain cytokines associated with enhanced recruitment of bone marrow-derived cells into the brain in neurodegeneration (神経変性における脳内サイトカイン環境変化と骨髄由来細胞の脳への進入亢進)2015

    • Author(s)
      Hasegawa-Ishii S, Inaba M, Li M, Umegaki H, Ikehara S and Shimada A
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸市
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-25290020
  • [Presentation] Selective localization of bone marrow-derived ramified cells in the brain adjacent to the attachments of choroid plexus2013

    • Author(s)
      Hasegawa-Ishii S, Shimada A, Inaba M, Li M, Shi M, Takei S and Ikehara S
    • Organizer
      PsychoNeuroImmunology Research Society’s 20th Annual Scientific Meeting
    • Place of Presentation
      Radisson Blu Royal Park Hotel, SE 169 03 Solna, Stockholm, Sweden
    • Data Source
      KAKENHI-PROJECT-25290020
  • [Presentation] 脳と免疫系の接点としての脈絡叢間質および付着部における細胞動態とサイトカイン発現2013

    • Author(s)
      石井さなえ、島田厚良、稲葉宗夫、李銘、石明、河村則子、武井史郎、千葉陽一、細川昌則、池原 進
    • Organizer
      第54回日本神経病理学会総会
    • Place of Presentation
      タワーホール船堀、東京
    • Data Source
      KAKENHI-PROJECT-25290020
  • [Presentation] 骨髄由来細胞の脈絡叢を経路とする脳への進入機構とその老化による変容

    • Author(s)
      島田厚良、石井さなえ、稲葉宗夫、李銘、石明、池原進
    • Organizer
      第120回日本解剖学会総会・学術集会
    • Place of Presentation
      神戸国際会議場、神戸市
    • Year and Date
      2015-03-21 – 2015-03-23
    • Data Source
      KAKENHI-PROJECT-25290020
  • [Presentation] Changes in profiles of brain cytokines associated with enhanced recruitment of bone marrow-derived cells into the brain in senescence-accelerated mice.

    • Author(s)
      Hasegawa-Ishii S, Ikehara S, Inaba M, Li M, Shi M Takei S and Shimada A
    • Organizer
      PsychoNeuroImmunology Research Society’s 21th Annual Scientific Meeting
    • Place of Presentation
      Philadelphia, Pennsylvania, USA
    • Year and Date
      2014-05-28 – 2014-05-31
    • Data Source
      KAKENHI-PROJECT-25290020
  • [Presentation] SAMマウスにおける骨髄由来細胞の脳へのリクルート亢進に関与する脳内サイトカイン環境の変化

    • Author(s)
      石井さなえ、池原進、稲葉宗夫、李銘、石明、島田厚良
    • Organizer
      第37回日本基礎老化学会大会
    • Place of Presentation
      国立長寿医療研究センター、大府市
    • Year and Date
      2014-06-26 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-25290020
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    # of Collaborated Projects: 17 results
    # of Collaborated Products: 10 results
  • 2.  TOKI Junko (40077681)
    # of Collaborated Projects: 16 results
    # of Collaborated Products: 0 results
  • 3.  YASUMIZU Ryoji (00142753)
    # of Collaborated Projects: 15 results
    # of Collaborated Products: 0 results
  • 4.  HISHA Hiroko (90151422)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 0 results
  • 5.  ADACHI Yasushi (10268336)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 6.  NAGATA Norikazu (40155940)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 7.  杉浦 喜久弥 (30171143)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  OGATA Hajime (50169174)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  SONODA Yoshiaki (60206688)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 10.  KIMURA Takafumi (30275193)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 11.  HOSAKA Naoki (30388459)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  NAKAMURA Masaya (20237431)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  IIDA Hirokazu (60176047)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  AKAGI Shigeo (80148501)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MIYASHIMA Shigeo (90288837)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ESUMI Takashi (20351504)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KAWAMOTO Keiji (70077741)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  YOSHIMURA Kunikazu (60298891)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KAKAZU Naoki (20264757)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  Shimada Atsuyoshi (50311444)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 21.  KUZUYA Masafumi (10283441)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  川喜田 睦司 (50252458)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  松田 公志 (20192338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  土井 浩 (60227692)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  大江 知里 (40469242)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  神田 靖士 (70295799)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  下埜 敬紀 (40632625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  小野江 和則 (40002117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  岩渕 和也 (20184898)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  奥山 春枝 (80001733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  柿沼 光明 (00001735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  小柳津 直樹 (20148513)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  沼 義博 (40208278)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  WOODWARD David
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  WATANABE Kikuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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