HARADA Takayuki 原田孝之

Researcher Number	90112135
Other IDs
Affiliation (based on the past Project Information) *help	2005 – 2007: 島根大学, 医学部, 教授 1994 – 1996: 島根医科大学, 医学部, 教授 1991 – 1992: 島根医科大学, 医学部, 助教授 1988 – 1989: 島根医科大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Experimental pathology / Otorhinolaryngology / Experimental pathology Except Principal Investigator Experimental pathology / Digestive surgery
Keywords	Principal Investigator アポトーシス / Nnal GENE / MUTANT / AMS MOUSE / NEURAL CELL DEATH / CASPASE / APOPTOSIS / PURKINJYE CELL / CEREBELLAR ATAXIA / 神経細胞死 … More / プルキンエ細胞 / Nna1遺伝子 / 小脳性失調症 / ミュータント / トランスフェクション / 細胞死 / 点突然変異 / Nnal遺伝子 / AMSマウス / human / immunocytochemistry / nucleus / cross-reactivity / squamous cell / Inositol 1,4,5-trisphosphate receptor / 頭頚部癌細胞 / イノシトール三燐酸レセプター / 免疫組織細胞化学 / 扁平上皮細胞 / ヒト / 扁平上皮癌細胞 / 交叉反応性 / 免疫細胞化学 / 単クローン抗体 / イノシトール三燐酸受容体 / S phase cell / Apoptosis / Cytokine / Immunohistochemistry / Thymus / Spleen / T cell / Chronic GvH disease / IFN-8 / MHCクラスII抗原 / CD8T細胞 / CD4T細胞 / サイトフルオロメトリー / 急性GvH病 / S期細胞 / サイトカイン / 免疫組織化学 / 胸腺 / 脾臓 / T細胞 / 慢性GvH病 … More Except Principal Investigator Ferritin / Mast Cell-Deficient Mouse / T cell / Macrophage / Mast Cell / Mouse / Jones-Mote type / Delayed Hypersensitivity / 足蹠反応 / モート型 / ジョンズ / 遅延型アレルギー / フェリチン / 肥満細胞欠損マウス / T細胞 / マクロファ-ジ / 肥満細胞 / マウス / ジョンズ・モ-ト型 / 遅延型アレルギ- / Epidermal growth factor(EGF) / Flowcytometry / Adhesion molecules / Experimental lymph node metastasis / Nude mice / Human esophageal cancer cell line / 抗アシアロGMI抗体 / NK細胞活性 / 上皮性増殖因子 / ラミニン / フィブロネクチン / 食道癌培養細胞 / エストロゲンレセプター / 血管内皮細胞 / 上皮性増殖因子(EGF) / フローサイトメトリー / 細胞表面接着因子 / リンパ節転移 / ヌードマウス / ヒト食道癌由来培養細胞株 Less

ANALYSIS OF FUNCTION OF THE DISEASE-RESPONSIBLE GENIE Nnal FOR A MUTANT MOUSE EXHIBITING CEREBELLAR ATAXIA AND MALE STERILITYPrincipal Investigator
- Principal Investigator
  
  HARADA Takayuki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Shimane University
Expression of Inositol, 1,4,5-trisphosphate Receptor in the Nucleus of Human Benign and Malignant Squamous Cells and Its SignificancePrincipal Investigator
- Principal Investigator
  
  HARADA Takayuki, KATOH Taiji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Shimane Medical University
In Situ Immunocytological and Molecular Pathological Analysis of the Lesions in the Target Organs of Chronic GvH DiseasePrincipal Investigator
- Principal Investigator
  
  HARADA Takayuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Shimane Medical University
Experimental study on lymph node metastasis of human esophageal cancer in nude mice.
- Principal Investigator
  
  NAKAMURA Teruhisa
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Shimane Medical University
Mast Cell-dependent Delayed Hypersensitivity (Jones-Mote type) and Analysis for Cellular Mechanism of the Response.
- Principal Investigator
  
  MORIKAWA Shigeru
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Shimane Medical University

All 2007 2006 2005

All Journal Article Presentation

[Journal Article] Different types of neural cell death in the cerebellum of the ataxia and male sterility (Al1S) mutant mouse2006
- Author(s)
  Li, Zhou, Asuka Araki, Akinobu, Nakano, Cent, Sezer, Takayuki, Harada
- Journal Title
  
  Pathology International 56
  
  Pages: 173-180
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Journal Article] Different types of neural cell death in the cerebellum of the ataxia and male sterility(AMS)mutant mouse.2006
- Author(s)
  Li Zhou, Asuka Araki, Akinobu Nakano, Cem Sezer, Takayuki Harada
- Journal Title
  
  Pathology International 56(6)巻
  
  Pages: 173-180
- NAID
  10018196231
- Data Source
  KAKENHI-PROJECT-17590347
[Journal Article] Ataxia and Male Sterility(AMS)ミュータントマウスの疾患責任遺伝子amsの異変と異なる種類の細胞死 (優秀選抜論文)2006
- Author(s)
  周麗, 原田孝之, 他
- Journal Title
  
  日本疾患モデル学会記録 22巻
  
  Pages: 19-25
- Data Source
  KAKENHI-PROJECT-17590347
[Journal Article] Different types of neural cell death in the cerebellum of the ataxia and male sterility (AMS) mutant mouse.2006
- Author(s)
  Li Zhou, Asuka Araki, Akinobu Nakano, Cem Sezer and Takayuki Harada
- Journal Title
  
  Pathology International 56
  
  Pages: 173-180
- NAID
  10018196231
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590347
[Journal Article] Ataxia and Male Sterility (AMS)ミュータントマウスの疾患責任遺伝子amsの変異と異なる種類の細胞死(優秀選抜論文)2006
- Author(s)
  周麗, 張傑, 荒木亜寿香, 中野晃伸, 原田孝之, 小野栄夫, 能勢真人
- Journal Title
  
  日本疾患モデル学会記録 22
  
  Pages: 19-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Journal Article] emsmutation of the disease-responsibleAheigene of the Ataxia and Male Sterility (AMS) mouse and its different types of cell death(The selected paper of the meeting)2006
- Author(s)
  Li, Zhou, Jie, Zhang, Asuka, Araki, Akinobu, Nakano, Takayuki, Harada, Masao, Ono, Masato, Nose
- Journal Title
  
  Proceedings of the Japanese Society of Animal Models for Human Diseases 22
  
  Pages: 19-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Journal Article] Kim : Immortalized Human Microglial cell Line. Phenotypic Expresson2005
- Author(s)
  Atushi, Nagai, Seiji, Mishima, Yuri, Ishida, Hiroto, Ishikura, Takayuki, Harada, Syotai, Kobayashi, Seung, U
- Journal Title
  
  Journal of Neuroscience Research 81
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Journal Article] Immortalized Human Microglial cell Line2005
- Author(s)
  Atushi Nagai, Seiji Mishima, Yuri Ishida, Hiroto Ishikura, Takayuki Harada, Syotai Kobayashi, Seune U. Kim
- Journal Title
  
  Phenotypic Expresson Journal of Neuroscience Research 81
  
  Pages: 1-7
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Neural and Male Germ Cell Mutant AMS Mouse : 15. Interrelation between ams mutation and genes relating to the regulation of apoptosis2007
- Author(s)
  Takayuki, Harada, Akinobu, Nakano, Asuka, Araki
- Organizer
  96I'Annual Meeting of the Japansese Society of Pathology
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Analysis of the level of importance of the ams mutation of the Mal gene in different cell populations of the Ataxia and Male Sterility mouse2007
- Author(s)
  T., HARADA, H., ARAKI, A., NAKANO, A., ARAKI, A., NAGAI
- Organizer
  Neuroscience2007. 37th annual meeting of the Society for Neuroscience
- Place of Presentation
  San Diego
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Analysis of the level of importance of the ams mutation of the Nnalgene in different cell populations of the Ataxia and Male Sterility2007
- Author(s)
  T. HARADA, H. ARAKI, A. NAKANO, A. ARAKI and A. NAGAI
- Organizer
  Neuroscience2007
- Place of Presentation
  San Diego
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] 神経・雄性生殖器系ミュータントAMSマウス:15.ams変異とapoptosis関連遺伝子の相互作用2007
- Author(s)
  原田孝之、中野晃伸、荒木亜寿香
- Organizer
  第96回日本病理学会総会
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Analysis of the level of importance of the ams mutation of the Nnal gene in different cell populations of the Ataxia and Male Sterility mouse2007
- Author(s)
  T. HARADA, H. ARAKI, A. NAKANO, A. ARAKI, A. NAGAI
- Organizer
  Neuroscience2007
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Ataxia and Male Sterility (AMS) Mutant Mouse : Functional loss of a single gene (final) leads to various histo- and cyto-pathological changes2006
- Author(s)
  Takayuki, Harada, Asuka, Araki, Li, Zhou, Jie, Zhang, Akinobu, Nakano, Masao, Ono, Masato Nose
- Organizer
  3rd Pathology Conference of the Japanese Society of Pathology
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Research in Basic Medicine utilizing Animal Models of Human diseases2006
- Author(s)
  Takayuki, Harada
- Organizer
  International symposium, Ningxia Medical College and Shimane University School of Medicine
- Place of Presentation
  Ningxia
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] 神経・雄性生殖器系ミュータントamsマウス:14網膜視細胞のアポトーシス感受性の亢進.2006
- Author(s)
  荒木亜寿香, 周麗, 中野晃伸, 大平明弘, 原田孝之
- Organizer
  第95回日本病理学会総会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Neural and Male Germ Cell Mutant AMS Mouse : 14. Acceleration of sensitivity to apoptosis of photoreceptor cells of the AMS retina2006
- Author(s)
  Asuka, Araki, Li, Zhou, Akinobu, Nakano, Akihiro, Ohira, Takayuki, Harada
- Organizer
  95th Annual Meeting of the Japanese Society of Pathology
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Neural and Male Germ Cell Mutant AMS Mouae : 13. genetic analysisof the disease-responsible ams mutation2006
- Author(s)
  Takayuki, Harada, Jie, Zhang, Asuka, Araki, Akinobn, Nakano, Li, Zhou, Masao, One, Masato, Nose
- Organizer
  95th Annual Meeting of the Japanese Society of Pathology
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Ataxia and Male Sterility (AMS)ミュータントマウス:単一遺伝子(Nnal)の昨日欠損による多様な組織病理学的・細胞病理学的変化2006
- Author(s)
  原田孝之, 荒木亜寿香, 周麗, 張傑, 中野晃伸, 小野栄夫, 能勢眞人
- Organizer
  第3回日本病理学会カンファレンス
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] The ams mutation of the Arnal gene of the Ataxia and Male Sterility mouse is a point mutation that affects expression of the protein but not transcription of the mRNA2006
- Author(s)
  Takayuki, Harada, Asuka, Araki, Akinobu, Nakano, Tie, Zhang, Atsushi, Nagai, andMasao, Ono
- Organizer
  Neuroscience 2006, 36th annual meeting of the Society for Neuroscience
- Place of Presentation
  Atlanta
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Reseach in Basic Medicine utilizing Animal Models of Human diseases2006
- Author(s)
  Takayuki Harada
- Organizer
  寧夏医学院島根大学医学部学術交流シンポジウム
- Place of Presentation
  中国寧夏医学院
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] The ams mutation of the Nnal gene of the Ataxia and Male Sterility mouse is a point mutation that affects expression of the protein but not transcription of the mRNA.2006
- Author(s)
  Takayuki Harada, Asuka Araki, Akinobu Nakano, Jie Zhang, Atsushi Nagai and Masao Ono
- Organizer
  Neuroscience 2006, 36th annual meeting of the Society for Neuroscience
- Place of Presentation
  Atlanta
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Effeet of the ems mutation in the Ataxia and Male Sterility (AMS) mouse on photic injury to photoreceptor cells2006
- Author(s)
  Asuka, Araki, Akinobu, Nakano, Li, Zhou, Riruke, Maruyama, Akihiro, Ohira, Takaybki, Harada
- Organizer
  The Seventh Joint Meeting of the Japan Society of Histochemistry and Cytochemistry and the US Histochemical Society. Waikoloa
- Place of Presentation
  Hawaii
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Effect of the ams mutation in the Ataxia and Male Sterility (AMS) mouse on photic injury to photoreceptor cells.2006
- Author(s)
  Asuka Araki, Akinobu Nakano, Li Zhou, Riruke Maruyama, Akihiro Ohira and Takayuki Harada
- Organizer
  The Seventh Joint Meeting of the Japan Society of Histochemistry and Cytochemistry and the US Histochemical Society.
- Place of Presentation
  Waikoloa, Hawaii
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] 神経・雄性生殖器系ミュータントAMSマウス:13病変責任遺伝子のams変異の同定2006
- Author(s)
  原田孝之, 張傑, 荒木亜寿香, 中野晃伸, 周麗, 小野栄夫, 能勢真人
- Organizer
  第95回日本病理学会総会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Neural and Male GermCell Mutant : AMS Mouse : 41. Acceleration of the PhOtoieceptot Cell Death by Photic Injury in AMS Retina2005
- Author(s)
  Li, Zhbu, Asuka, Araki, AkinobuNakano, Yu, Ryu, Akihiro, Ohira, lakayuki, Harada
- Organizer
  46th AnnOrMeatina of the Japanese Society forthStoebeinittrYand-Cytochemistry
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] 神経・雄性生殖系ミュータントAMSマウス:11.光刺激による網膜視細胞死の促進2005
- Author(s)
  周麗, 荒木亜寿香, 中野晃伸, 柳勇, 大平明弘, 原田孝之
- Organizer
  第46回日本組織細胞化学会
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] 神経・雄性生殖系ミュータントAMSマウス:10.小脳神経細胞死におけるカスパーゼの動態.2005
- Author(s)
  周麗, 中野晃伸, 荒木亜寿香, 原田孝之
- Organizer
  第94回日本病理学会総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Neural and Male ; Genstell Mutant ARS Mouse : 12. ems mutation of the disease-responsible gene and different types of cell death2005
- Author(s)
  Li, Zhoti, Jie, Zhiag, AsUka, Araki, Akinobu, Nakano, Masao, Ono, Masato Nnae, TakaYuki, Harada
- Organizer
  22nd Annual Meeting of the Japanese Society of Animal Models for Human Diseases
- Place of Presentation
  Ikaho
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] Neural and Male Germ Cell Mutant AMS Mouse : It Kinetics of Caspases in Neural Cell Death of the AMS Cerebellum2005
- Author(s)
  Li, Zhou, Akinobu, Nakano, Asuka, Araki, Takayuki, Harada
- Organizer
  94th Annual Meeting of the Japanese Society of Pathology
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590347
[Presentation] 神経・雄性生殖系ミュータントAMSマウス:12.疾患責任遺伝子Nnalのams変異と異なる種類の細胞死2005
- Author(s)
  周麗, 張傑, 荒木亜寿香, 中野晃伸, 小野栄夫, 能勢真人, 原田孝之
- Organizer
  第22回日本疾患モデル学会総会
- Place of Presentation
  群馬
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590347

1. MORIKAWA Shigeru (80027094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KATOH Taiji (20185846)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NAKAMURA Teruhisa (10038656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KUBOTA Hirofumi (00205147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KAWAUCHI Hideyuki (50161279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SHIBA Hiromi (30281760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SANO Keisuke (10263542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OHIRA Akihiro (00169054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. NAKANO Akinobu (70263514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
10. TORII Ikuko (70207661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HARADA Takayuki 原田 孝之

Research Projects

Research Products

Co-Researchers

ANALYSIS OF FUNCTION OF THE DISEASE-RESPONSIBLE GENIE Nnal FOR A MUTANT MOUSE EXHIBITING CEREBELLAR ATAXIA AND MALE STERILITYPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression of Inositol, 1,4,5-trisphosphate Receptor in the Nucleus of Human Benign and Malignant Squamous Cells and Its SignificancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In Situ Immunocytological and Molecular Pathological Analysis of the Lesions in the Target Organs of Chronic GvH DiseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental study on lymph node metastasis of human esophageal cancer in nude mice.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mast Cell-dependent Delayed Hypersensitivity (Jones-Mote type) and Analysis for Cellular Mechanism of the Response.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Different types of neural cell death in the cerebellum of the ataxia and male sterility (Al1S) mutant mouse2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Different types of neural cell death in the cerebellum of the ataxia and male sterility(AMS)mutant mouse.2006

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Ataxia and Male Sterility(AMS)ミュータントマウスの疾患責任遺伝子amsの異変と異なる種類の細胞死 (優秀選抜論文)2006

Author(s)

Journal Title

Data Source

[Journal Article] Different types of neural cell death in the cerebellum of the ataxia and male sterility (AMS) mutant mouse.2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Ataxia and Male Sterility (AMS)ミュータントマウスの疾患責任遺伝子amsの変異と異なる種類の細胞死(優秀選抜論文)2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] emsmutation of the disease-responsibleAheigene of the Ataxia and Male Sterility (AMS) mouse and its different types of cell death(The selected paper of the meeting)2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Kim : Immortalized Human Microglial cell Line. Phenotypic Expresson2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Immortalized Human Microglial cell Line2005

Author(s)

Journal Title

Description

Data Source

[Presentation] Neural and Male Germ Cell Mutant AMS Mouse : 15. Interrelation between ams mutation and genes relating to the regulation of apoptosis2007

Author(s)

Organizer

Place of Presentation

Description

Data Source

HARADA Takayuki 原田孝之