MIYAZAKI Masahiro 宮崎正博

… Alternative Names

MASAHIRO Miyazaki 宮崎正博

宮崎正博ミヤザキマサヒロ

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Researcher Number	90116509
Other IDs
Affiliation (based on the past Project Information) *help	2012: 岡山学院大学, 人間生活学部, 教授 2007: Okayama Gakuin University, Department of Food and Nutrition, Faculty of Human Services, Professor 2005 – 2006: Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Associate Professor, 大学院・医歯薬学総合研究科, 助教授 2005 – 2006: 岡山大学, 大学院医歯薬学総合研究科, 助教授 2001 – 2004: Graduate School of Med. & Dent., Assoc. Prof., 大学院・医歯学総合研究科, 助教授 1999: 岡山大学, 医学部, 助教授 1992 – 1994: 岡山大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Experimental pathology / General medical chemistry Except Principal Investigator Biological Sciences / Dermatology / Urology / General surgery / Environmental impact assessment/Environmental policy
Keywords	Principal Investigator liver fibrosis / acute liver failure / transplantation / hepatocytes / a bone marrow-derived clonal mesenchymal stem cell / 肝線維症 / 急性肝不全 / 移植 / 肝細胞 / 骨髄間葉系幹細胞クローン … More / Malignant transformation / Aflatoxin B1 / Mutated p53 gene / Activated c-Ha-ras oncogene / Glutathione S-transferase pi / Immortalization / SV40 T-antigen gene / Human liver cells / SV40T-抗原遺伝子 / グルタチオンS-トランスフェラーゼπ / 癌化 / アフラトキシンB_1 / 点変異p53遺伝子 / 点変異ras遺伝子 / グルタチオン S-トランスフェラーゼπ / 不死化 / SV40 T-抗原遺伝子 / ヒト肝細胞 / インターロイキン-1β遺伝子発現 / インターロイキン-1β / ヒト肝細胞増殖因子の産生抑制因子 / ヒト肝細胞増殖因子の産生促進因子 / ヒト肝細胞増殖因子遺伝子発現 / ヒト肝細胞増殖因子産生 / 培養内加齢 / ヒト胎児肺由来線維芽細胞 … More Except Principal Investigator S100 / p21 / A11 / Bax / JNK / DKK / REIC / Hornerin / Ca / keratinization / differentiation / skin / 角化 / 分化 / RNA differential display / 皮膚 / アポトーシス / 増殖制御 / S100C / TGFβ / 増殖 / Adenovirus / Prostate cancer / Renal cancer / Apoptosis / 膀胱癌 / 腎細胞癌 / 遺伝子治療 / 精巣腫瘍 / 前立腺癌 / アデノウイルス / 前立腺がん / 腎がん / stem cells / growth regulation / 組織構築 / calmin / 骨髄 / Profilaggrin / profilaggrin / hornerin / 幹細胞 / porcine hepatocyte isolation / bioartificial liver / human liver endothelial cell line / human hepatocyte cell line / reversible immortalization / ブタ肝不全 / テロメレース / 不死化肝細胞 / ブタ肝細胞分離 / バイオ人工肝臓 / ヒト肝内皮細胞株 / ヒト肝細胞株 / 可逆性不死化 / Ca-binding / actin / filaggrin / gene / TPR / RNA differential diaplay / 海馬 / プルキンエ細胞 / PSD / Ca結合 / アクチン / フィラグリン / 遺伝子 / 環境影響評価 / 酸化ストレス / 美白クリーム / プロテオーム / カタラーゼ遺伝子変異マウス / 生体影響評価 / 化学物質の生体影響評価 / レスベラトロール / ローソン / ヒドロキノン / 過酸化水素 / カタラーゼ / 初代培養肝細胞 / Annexin A1 / ヒト表皮角化細胞 / 角化細胞 / 表皮 / 乾癬 / RAGE / EGF / がん / Annexin / 信号伝達 / 増殖抑制 / PCNA / 浸潤 / 細胞遊走 / 細胞周期 / β1,3-N-acetylglucosaminyltransferase / BRPK / タンパク質リン酸化 / 転移 / 癌化 / 不死化ヒト肝細胞株 / NS3遺伝子 / core遺伝子 / HCV / ヒト皮膚線維芽細胞 / 腫瘍細胞障害因子 / ヒト肝がん細胞 / ヒト肝細胞増殖因子 Less

Risk assessment of environmental oxidative chemicals using catalase mutant primary cultured hepatocytes
- Principal Investigator
  
  WANG Da-hong
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental impact assessment/Environmental policy
- Research Institution
  Okayama University
上皮細胞増殖制御の機能的ハプタンパク質S100Cの機能解明とがん治療への応用
- Principal Investigator
  
  許南浩
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
Basic research on treatment of liver failure and prevention against liver fibrosis by transplantation of MAPC-like stem cells established from bone marrowPrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Masahiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Okayama Gakuin University
  Okayama University
S100C/A11を介する新しいTGFβ増殖抑制信号伝達系の発がんにおける意義
- Principal Investigator
  
  許南浩
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
Research on Functional Analysis and Clinical application of New Tumor-associated Gene (REIC) in Urogenital Cancer
- Principal Investigator
  
  NASU Yasutomo
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
新規がん転移関連遺伝子(タンパク質リン酸化酵素BRPK、糖転移酵素3H8)の解析
- Principal Investigator
  
  HUH Nam-ho
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
Relevance of genes involved in skin tissue formation to human diseases and its application for regenerative medicine.
- Principal Investigator
  
  HUH Nam-ho
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Okayama University
Bioartificial liver development using reversibly immortalized human liver cell lines.
- Principal Investigator
  
  TANAKA Noriaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Okayama University
肝特異機能をもつ培養化ヒト肝細胞のHCVによる発癌
- Principal Investigator
  
  難波正義
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
Systematic Isolation of Novel Genes Involved in Regulation of Growth and Differentiation of Slain Cells and Their Relevance to Human Diseases.
- Principal Investigator
  
  HUH Nam-ho
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  OKAYAMA UNIVERSITY
  Toyama Medical and Pharmaceutical University
ヒト線維芽細胞の肝細胞増殖因子産生能に及ぼす組織提供者の年齢Principal Investigator
- Principal Investigator
  
  宮崎正博
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Okayama University
肝細胞増殖因子に対して異なる増殖応答性を示す分化型ヒト肝がん細胞の特性
- Principal Investigator
  
  合田栄一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Okayama University
Studies on establishment and malignant transformation of cell lines from normal human liverPrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Masahiro
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Okayama University Medical School

All 2012 2011 2010 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] Resveratrol Inhibited Hydroquinone- induced Cytotoxicity in Mouse Primary Hepatocytes2012
- Author(s)
  Wang DH, Ootsuki Y, Fujita H, Miyazaki M, Yie Q, Tsutsui K, Sano K, Masuoka N, Ogino K
- Journal Title
  
  Int. J. Environ Res & Public Health
  
  Volume: 9 Pages: 3354-3364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310022
[Journal Article] Resveratrol Inhibited Hydroquinone-induced Cytotoxicity in Mouse Primary Hepatocytes.2012
- Author(s)
  (Wang DH), Otsuki Y, Fujita H, Miyazaki M, Yie Q, Tsutsui K, Sano K, Masuoka N, Ogino K.
- Journal Title
  
  Int J Environ Res & Public Health
  
  Volume: 9 Issue: 9 Pages: 3354-3364
- DOI
  10.3390/ijerph9093354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310022, KAKENHI-PROJECT-23310133, KAKENHI-PROJECT-24592263
[Journal Article] A new risk assessment method for evaluation of oxidative chemicals using catalase mutant mouse primary hepatocytes2011
- Author(s)
  Wang DH, Ishikawa Y, Miyazaki M, Fujita H, Tsutsui K, Sano K, Masuoka N, Ogino K
- Journal Title
  
  Health
  
  Volume: 3 Pages: 288-291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310022
[Journal Article] Isolation of a bone marrow-derived stem cell line with high proliferation potential and its application for preventing acute fatal liver failure2007
- Author(s)
  Miyazaki M, Hardjo M, Masaka T, Tomiyama K, Mahmut N, et. al.
- Journal Title
  
  Stem Cells 25
  
  Pages: 2855-2863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590269
[Journal Article] Isolation of a bone marrow-derived stem cell line with high proliferation potential and its application for preventing acute fatal liver failure.2007
- Author(s)
  Miyazaki M, Hardjo M, Masaka T, Tomiyama K, Mahmut N, Medina RJ, Niida A, Sonegawa H, Du G, Yong R, Takaishi M, Sakaguchi M, Huh NH
- Journal Title
  
  Stem Cells(reviewed paper) 25
  
  Pages: 2855-2863
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590269
[Journal Article] Isolation of a bone marrow-derived stem cell line with high proliferation potential and its application for preventing acute fatal liver failure2007
- Author(s)
  Masahiro Miyazaki
- Journal Title
  
  Stem Cells 25
  
  Pages: 2855-2863
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590269
[Journal Article] Bifurcated converging pathways for high Ca- and TGF-induced inhibition of growth of normal human keratinocytes2005
- Author(s)
  M.Sakaguchi, M.Miyazaki, M.Huh
- Journal Title
  
  Proc Natl Acad Sci USA 102
  
  Pages: 13921-13926
- Data Source
  KAKENHI-PROJECT-15390491
[Journal Article] Involvement of interferon regulatory factor 1 and S100C/A11 in growth inhibition by transforming growth factor beta 1 in human hepatocellular carcinoma cells2004
- Author(s)
  Miyazaki
- Journal Title
  
  Cancer Research 64(12)
  
  Pages: 4155-4161
- Data Source
  KAKENHI-PROJECT-14370260
[Journal Article] PKCalpha mediates TGFbeta-induced growth inhibition of human keratinocytes via phosphorylation of S100C/A11.2004
- Author(s)
  Sakaguchi M, Miyazaki M, Sonegawa H, Kashiwagi M, Ohba M, Kuroki T, Namba M, Huh NH
- Journal Title
  
  J Cell Biol. 164(7)
  
  Pages: 979-984
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370260
[Journal Article] Propagation of adult rat bone marrow-derived hepatocyte-like cells by serial passages in vitro.2004
- Author(s)
  Miyazaki et al.
- Journal Title
  
  Cell Transplantation 13(4)
  
  Pages: 385-391
- Data Source
  KAKENHI-PROJECT-14370260
[Journal Article] S100C/A11 is a key mediator of Ca(2+)-induced growth inhibition of human epidermal keratinocytes.2003
- Author(s)
  Sakaguchi M, Miyazaki M, Takaishi M, Sakaguchi Y, Makino E, Kataoka N, Yamada H, Namba M, Huh NH
- Journal Title
  
  J Cell Biol. 163(4)
  
  Pages: 825-835
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370260
[Journal Article] Participation of adult mouse bone marrow cells in reconstitution of skin.2003
- Author(s)
  Kataoka K, Medina RJ, Kageyama T, Miyazaki M, Yoshino T, Makino T, Huh NH
- Journal Title
  
  Am J Pathol. 163(4)
  
  Pages: 1227-1231
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370260
[Presentation] Risk assessment of environmental oxidative chemicals using catalase mutant primary cultured hepatocytes.2012
- Author(s)
  (Dahong Wang), Masahiro Miyazaki, Hirofumi Fujita, Ken Tsutsui, Kuniaki Sano, Noriyoshi Masuoka, Keiki Ogino
- Organizer
  The American Public Health Association's 140th Annual Meeting and Exposition.
- Place of Presentation
  The Moscone Convention Center West, San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] 初代培養肝細胞におけるヒドロキノンの影響とレスベラトロールの抑制効果2012
- Author(s)
  叶欽霞、汪達紘、大月芳恵、石川靖夫、藤田洋史、宮崎正博、筒井研、佐野訓明、益岡典芳、荻野景規
- Organizer
  第82回日本衛生学会学術総会
- Place of Presentation
  京都大学吉田キャンパス
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] Risk assessment of environmental oxidative chemicals using catalase mutant primary cultured hepatocytes2012
- Author(s)
  Wang DH, Miyazaki M, Fujita H, Tsutsui K, Sano K, Masuoka N, Ogino K
- Organizer
  The American Public Health Association's 140th Annual Meeting and Exposition, The Moscone Convention Center West
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2012-10-29
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] 低カタラーゼ活性マウスの初代培養肝細胞を用いた環境化学物質評価法の開発(第2報)2011
- Author(s)
  大月芳恵、汪達紘、石川靖夫、藤田洋史、宮崎正博、筒井研、佐野訓明、瀧川智子、荻野景規
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学旗の台キャンパス
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] 低カタラーゼ活性マウスの初代培養肝細胞を用いた環境化学物質評価法の開発 (第2報)2011
- Author(s)
  大月芳恵、汪達紘、石川靖夫、藤田洋史、宮崎正博、筒井研、佐野訓明、瀧川智子、荻野景規
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学旗の台キャンパス
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] カタラーゼ括性の異なるマウスの初代培養肝細胞に及ぼすヒドロキノンの影響2010
- Author(s)
  大月芳恵、汪達紘、石川靖夫、藤田洋史、宮崎正博、筒井研、佐野訓明、瀧川智子、荻野景規
- Organizer
  第8回日本予防医学会学術総会
- Place of Presentation
  石川県立音楽堂交流ホール
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] カタラーゼ活性の異なるマウスの初代培養肝細胞に及ぼすヒドロキノンの影響2010
- Author(s)
  大月芳恵、汪達紘、石川靖夫、藤田洋史、宮崎正博、筒井研、佐野訓明、瀧川智子、荻野景規
- Organizer
  第8回日本予防医学会学術総会
- Place of Presentation
  石川県立音楽堂交流ホール
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] 低カタラーゼ活性マウスの初代培養肝細胞を用いた環境化学物質評価法の開発(第1報)2010
- Author(s)
  汪達紘、石川靖夫、宮崎正博、藤田洋史、筒井研、佐野訓明、益岡典芳、瀧川智子、高木二郎、荻野景規
- Organizer
  第80回日本衛生学会学術総会
- Place of Presentation
  仙台市国際センター
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] ラット急性肝不全モデル救命効果を示す骨髄由来幹細胞クローンの特性2007
- Author(s)
  宮崎正博
- Organizer
  第6回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-03-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590269
[Presentation] Characteristics of bone marrow-derived clonal stem cell lines having therapeutic potential for rescue of rats with fatal acute liver failure.2007
- Author(s)
  Miyazaki M
- Organizer
  6th Annual Meeting of Japanese Society for RegenerativeMedicine
- Place of Presentation
  Yokohama
- Year and Date
  2007-03-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590269
[Presentation] Rescue of 90%-hepatectomized rats with acute liver failure by intrasplenic transplantation of hepatocytes derived from a newly established mesenchymal stem cell line from rat bone marrow.2006
- Author(s)
  Miyazaki M
- Organizer
  79th Annual Meeting of Japanese Tissue Culture Association
- Place of Presentation
  Tokyo
- Year and Date
  2006-05-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590269
[Presentation] Rescue of 90% hepatectomized rats with acute liver failure by intrasplenic transplantation of hepatocytes derived from bone marrow stem cells.2006
- Author(s)
  Miyazaki M
- Organizer
  15th National Congress of Indonesian Association of Pathologist
- Place of Presentation
  Semarang, Indonesia
- Year and Date
  2006-08-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590269
[Presentation] Rescue of 90% hepatectomized rats with acute liver failure by intras plenic transplantation of hepatocytes derived from bone marrow stem cells2006
- Author(s)
  Masahiro Miyazaki
- Organizer
  Guest Lecture at the 15th National Congress of Indonesian Association of Pathologist
- Place of Presentation
  Semarang,Indonesia
- Year and Date
  2006-08-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590269

1. HUH Nam-ho (70173573)

# of Collaborated Projects: 7 results

# of Collaborated Products: 5 results
2. SAKAGUCHI Masakiyo (70379840)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. TSUTSUI Ken (70108158)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
4. SANO Kuniaki (00294405)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
5. NAKAMURA Kazuyuki (90107748)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MOROHASHI Masaaki (50018719)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TAKAISHI Mikiro (10303223)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. WANG Da-hong (90294404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
9. FUJITA Hirofumi (20423288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
10. OGINO Keiki (70204104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
11. MASUOKA Noriyoshi (20116502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. TANAKA Noriaki (10127566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YOKOI Tsuyoshi (70135226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KOIDE Norio (20142333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KATAOKA Ken (10293317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. NASU Yasutomo (20237572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KUMON Hiromi (30144760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. EBARA Shin (70379741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 合田栄一 (20028814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 難波正義 (80069004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 山田雅夫 (40166731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 井上裕介 (90304302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 娜依拉馬合木提 (90423342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NAKAJI Syuhei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SADAMORI Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MIYAZAKI Masahiro 宮崎 正博

MASAHIRO Miyazaki 宮崎 正博

宮崎 正博 ミヤザキ マサヒロ

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Basic research on treatment of liver failure and prevention against liver fibrosis by transplantation of MAPC-like stem cells established from bone marrowPrincipal Investigator

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ヒト線維芽細胞の肝細胞増殖因子産生能に及ぼす組織提供者の年齢Principal Investigator

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Studies on establishment and malignant transformation of cell lines from normal human liverPrincipal Investigator

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[Journal Article] Resveratrol Inhibited Hydroquinone- induced Cytotoxicity in Mouse Primary Hepatocytes2012

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[Journal Article] Resveratrol Inhibited Hydroquinone-induced Cytotoxicity in Mouse Primary Hepatocytes.2012

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MIYAZAKI Masahiro 宮崎正博

MASAHIRO Miyazaki 宮崎正博

宮崎正博ミヤザキマサヒロ