SUGIMOTO Tohru 杉本徹

Researcher Number	90117888
External Links
Affiliation (based on the past Project Information) *help	2003 – 2006: Kyoto Prefectural University of Medicine, Professor, 医学研究科, 教授 2000 – 2002: 京都府立医科大学, 医学部, 教授 1993 – 1999: Miyazaki Medical College, Pediatrics, Professor, 医学部, 教授 1990 – 1992: 京都府立医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics Except Principal Investigator Pediatrics / Pediatrics
Keywords	Principal Investigator 神経芽腫 / Neuroblastoma / Smooth muscle cell / 分化・成熟 / 平滑筋細胞 / ヒト神経芽腫 / real-time PCR / DCR2 / 分化 / 増殖 … More / 神経栄養因子 / Differentiation / 細胞シグナル伝達 / アポトーシス / Fenretinide / レチノイド / 細胞分化 / serum DNA / aberrant methvlation / Neurnhlastnma / 微小残存腫瘍 / Real-time PCR / DCR2メチレーション / 血清DNA / 異常メチル化 / Fenrefinide / Retinoid / Neurotrophic factor / Apoptosis / Growth / 生存 / ひと神経芽腫 / Substrate-adhesive (S)-type cell / Neural crest cell / 神経堤細胞 / S型細胞 / 神経冠 / GROWTH AND DIFFERENTIALTION / SIGNAL TRANSDUCTION / TRK-FAMILY RECEPTORS / NEUROTROPHIC FACTORS / NEUROBLASTOMA / TRK-B受容体 / TRK-A受容体 / 増殖と分化 / シグナル伝達 / TRK family受容体 / Nerve Growth Factor Receptor / Maturation / Differentiaion / 神経成長因子受容体 / Neuronal cell / Cell differentiation / Human neuroblastoma / 分化能 / ヒト神経芽胞 / 神経細胞 / nuroblastoma / 細胞内活性酸素種 / 細胞内シグナル伝達 / 分化誘導療法 / サイトカイン / 分化と増殖 … More Except Principal Investigator 神経芽腫 / Real-time PCR / Real-time quantitative PCR / 血清遊離DNA / MYCN増幅 / アポトーシス / レチノイン酸 / 合成レチノイド / 細胞分化 Less

EVALUATION OF PROGNOSIS AND EFFICACY OF THERAPY FOR NEUROBLASTOMA PATIENTS BY QUANTIFICATION OF METHYLATED DCR2 GENE PROMOTER IN SERUM DNAPrincipal Investigator
- Principal Investigator
  
  HOSOI Hajime, 杉本徹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
神経芽腫担癌患児の血清中遊離DNAを用いた細胞遺伝子学的悪性度推定法の開発
- Principal Investigator
  
  HOSOI Hajime
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
新規合成レチノイドFenretinideによる神経芽腫のアポトーシスの機序の解明Principal Investigator
- Principal Investigator
  
  杉本徹
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
Growth, Differentiation, Survival and Apoptosis in Human Neuroblastoma CellsPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Tohru
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
Differentiation and maturation of human neuroblastoma cells into smooth muscle cellsPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Tohru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
SIGNAL TRANSDUCTION OF TRK-FAMILY RECEPTORS IN HUMAN NEUROBLASTOMAPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Tohru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Miyazaki Medical College
新規合成レチノイド(Am80,Ch55,Re80)によるヒト神経芽腫の細胞分化
- Principal Investigator
  
  糸数直哉
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  宮崎医科大学
Role of Nerve Growth Factor Receptor in Differentiation, Maturation and Spontaneous Regression of Human NeuroblastomaPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Tohru
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Miyazaki Medical College
ヒト神経芽腫の分化誘導療法の基礎的研究Principal Investigator
- Principal Investigator
  
  杉本徹
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  宮崎医科大学
Multipotent differentiation of human neuroblastoma cellsPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Tohru
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Miyazaki Medical College
  Kyoto Prefectural University of Medicine
サイトカインによるヒト神経芽腫の分化と増殖の機序の解明Principal Investigator
- Principal Investigator
  
  杉本徹
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto Prefectural University of Medicine
Differentiation and maturation of human neuroblastoma into smooth muscle cellsPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Tohru
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural Univ. of Medicine

All 2006 2004

All Journal Article Book

[Book] よく理解できる子どものがん (別所文雄、横森欣司編)2006
- Author(s)
  杉本徹, 家原知子, 細井創他
- Publisher
  永井書店、東京
- Data Source
  KAKENHI-PROJECT-18390300
[Journal Article] MYCN gene amplification is a powerful prognostic factor even in infantile neuroblastoma detected by mass screening.2006
- Author(s)
  Iehara T, Hosoi H, Sugimoto T, et al.
- Journal Title
  
  Br J Cancer. 94(10)
  
  Pages: 1510-5
- Data Source
  KAKENHI-PROJECT-18390300
[Journal Article] Fenretinide induces sustained-activation of JNK/p38 MAPK and a apoptpsis in a reactive oxygen species-dependent ・・・2004
- Author(s)
  Osone S, Sugimoto T, et al.
- Journal Title
  
  Int J Cancer 112(2)
  
  Pages: 219-224
- Data Source
  KAKENHI-PROJECT-15659249
[Journal Article] Antitumor activity of Gefitinib (Iressa), an epidermal growth factor receptor tyrosine kinase inhibior in・・・2004
- Author(s)
  Kuwahara, Sugimoto T, et al.
- Journal Title
  
  Clin Cancer Res 10(17)
  
  Pages: 5940-5948
- Data Source
  KAKENHI-PROJECT-15659249
[Journal Article] Translocaiton (1;22) (p36;q11.2) with concurrent del (22) (q11.2)resulted in homozygous deletion of SNF5/INI1 in a ・・・2004
- Author(s)
  Misawa A, Sugimoto T, et al.
- Journal Title
  
  Journal of Human Genetics 49
  
  Pages: 586-589
- Data Source
  KAKENHI-PROJECT-15659249

1. HOSOI Hajime (20238744)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. IEHARA Tomoko (20285266)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. KURODA Hiroshi (10284837)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HORII Yoshihiro (30264378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 糸数直哉 (90244194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SUGIMOTO Tohru 杉本 徹

Research Projects

Research Products

Co-Researchers

EVALUATION OF PROGNOSIS AND EFFICACY OF THERAPY FOR NEUROBLASTOMA PATIENTS BY QUANTIFICATION OF METHYLATED DCR2 GENE PROMOTER IN SERUM DNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経芽腫担癌患児の血清中遊離DNAを用いた細胞遺伝子学的悪性度推定法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規合成レチノイドFenretinideによる神経芽腫のアポトーシスの機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Growth, Differentiation, Survival and Apoptosis in Human Neuroblastoma CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Differentiation and maturation of human neuroblastoma cells into smooth muscle cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

SIGNAL TRANSDUCTION OF TRK-FAMILY RECEPTORS IN HUMAN NEUROBLASTOMAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規合成レチノイド(Am80,Ch55,Re80)によるヒト神経芽腫の細胞分化

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of Nerve Growth Factor Receptor in Differentiation, Maturation and Spontaneous Regression of Human NeuroblastomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト神経芽腫の分化誘導療法の基礎的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Multipotent differentiation of human neuroblastoma cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

サイトカインによるヒト神経芽腫の分化と増殖の機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Differentiation and maturation of human neuroblastoma into smooth muscle cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] よく理解できる子どものがん (別所文雄、横森欣司編)2006

Author(s)

Publisher

Data Source

[Journal Article] MYCN gene amplification is a powerful prognostic factor even in infantile neuroblastoma detected by mass screening.2006

Author(s)

SUGIMOTO Tohru 杉本徹