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Hosoi Hajime  細井 創

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HOSOI Hajime  細井 創

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Researcher Number 20238744
Other IDs
External Links
Affiliation (Current) 2022: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授
Affiliation (based on the past Project Information) *help 2021 – 2022: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授
2009 – 2020: 京都府立医科大学, 医学(系)研究科(研究院), 教授
2015: 京都府立医科大学, 大学院医学研究科, 教授
2015: 京都府立医科大学, 大学院医学研究科小児発達医学, 教授
2012: 京都府立医科大学, 大学院・医学研究科・小児発達医学, 教授 … More
2012: 京都府立医科大学, 大学院・医学研究科小児発達医学, 教授
2010 – 2011: 京都府立医科大学, 医学研究科, 教授
2007 – 2008: Kyoto Prefectural University of Medicine, Department of Pediatrics, Professor
2007: 京都府立医科大学, 医学部, 准教授
2006: 京都府立医科大学, 医学研究科, 准教授
2005 – 2006: 京都府立医科大学, 医学部, 助教授
2005: 京都府立医科大学, 医学研究科, 助教授
2004: Kyoto Prefectural University of Medicine, School of Medicine, Assistant Professor, 医学部, 講師
2003 – 2004: Kyoto Prefectural University of Medicine, Assistant Professor, 医学研究科, 講師
2003: 京都府立医科大学, 講師
2002: 京都府立医科大学, 医学部, 講師
1998 – 2000: 京都府立医科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Pediatrics / Pediatric surgery / Pediatrics / Basic Section 50020:Tumor diagnostics and therapeutics-related
Except Principal Investigator
Pediatrics / Pediatrics / Pediatric surgery / Pediatric surgery / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords
Principal Investigator
横紋筋肉腫 / 神経芽腫 / 融合遺伝子 / 小児がん / Real-time PCR / microRNA / ドラッグデリバリー / 免疫療法 / N-myc / IGF-I … More / MAPK / 細胞周期 / Myc / DCR2 / real-time PCR / エクソソーム / MYCN増幅 / 血清遊離DNA / Real-time quantitative PCR / 分子標的療法 / 腫瘍マーカー / 血清診断 / miR-206 / PAX3-FKHR / 融合遺云子 / exosome / トランスレーショナル・リサーチ / がん免疫療法 / liquid biopsy / トランスレーショナルリサーチ / 新規バイオマーカー / 免疫治療 / 樹状細胞 / 高リスク / 免疫チェックポイント / PD-L1 / PD-1 / レチノイン酸 / 分化誘導 / 神経芽細胞腫 / mycN / mxi1 / max / レチノイン酸誘導体 / neuroblastoma / retinoic acid / differentiation / ラパマイシン / インスリン様成長因子 / 細胞内情報伝達 / アポトーシス / 分化 / 増殖 / 横紋筋肉腫 (RMS) / MyoD / 筋最終分化 / ラプマイシン / eIF-4E / c-MYC / mTOR / Rhabdomyosarcoma / Rapamycin / Insulin-like Growth Factor / Signaltransduction / Apoptosis / Differentation / Proliferation / 異常メチル化 / 血清DNA / DCR2メチレーション / 微小残存腫瘍 / Neurnhlastnma / aberrant methvlation / serum DNA / CAR-T細胞 / 免疫疲弊 / ヒギーバックトランスポゾン / siRNA / 間葉系幹細胞 / 遺伝子改変T細胞 / 腫瘍溶解性アデノウイルス / CAR-T / 腫瘍溶解性ウイルス / CAR-T療法 / エフェクターサイトカイン / 制御性T細胞 / T-reg … More
Except Principal Investigator
横紋筋肉腫 / PAX3-FKHR / 小児がん / 臨床試験 / 中央病理診断 / PAX7-FKHR / VAC / 神経芽腫 / microRNA / アポトーシス / VOD / 胞巣型 / 胎児型 / miR-206 / liquid biopsy / 腫瘍マーカー / Rhabdomyosarcoma / clinical trial / peripheral blood stem cell / 神経芽細胞腫 / 骨転移 / IL-1β / Cathepsin K / cathepsin k / 小児 / 胎児型横紋筋肉腫 / 胞巣型横紋筋肉腫 / PAX-FKHR / PAX-GKHR / phox2b / ASCL1 / Notch / γsecretase / 分化誘導 / cancer stem cell / SP細胞 / iPS / canser stem cell / ips / 横紋筋肉 / PAX3,7/FKHR / 融合遺伝子 / LXXLL motif / 分子標的療法 / PAX3-NCOA2 / ラブドイド腫瘍 / SNF5 / クロマチンリモデリング / NOXA / 薬剤感受性 / 悪性ラブドイド腫瘍 / 薬剤耐性 / Mcl-1 / バイオマーカー / 転移 / スーパーハイリスク / ハイリスク / スーパーハイリスク / 再発 / PAX3 / PAX7 / グループスタディ / JRSG / リスク分類 / rhabdomyosarcoma / 放射線治療 / 外科治療 / children / ひと神経芽腫 / 増殖 / 分化 / 神経栄養因子 / レチノイド / Fenretinide / ヒト神経芽腫 / 生存 / Neuroblastoma / Growth / Differentiation / Apoptosis / Neurotrophic factor / Retinoid / Fenrefinide / 血清 / 髄液 / PD-L1 / 免疫療法 / PAX3-FOXO1 / B7-H3 / 抗PD-1抗体 / チェックポイント阻害剤 / HDAC阻害剤 / 小児腫瘍 / RAF-MEK阻害剤 / RAS変異 / MEK阻害剤 / RAS / プレシジョン医療 / CAR-T細胞療法 / KMT2A再構成 / 急性リンパ性白血病 / ピギーバックトランスポゾンベクター / CD19 / FLT3 / CAR-T細胞 / CAR-T療法 Less
  • Research Projects

    (25 results)
  • Research Products

    (171 results)
  • Co-Researchers

    (56 People)
  •  Development of CAR-T cell therapy complementary system for rhabdomyosarcoma using oncolytic virusPrincipal Investigator

    • Principal Investigator
      細井 創
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of CAR-T cell therapy for KMT2A-rearranged acute lymphoblastic leukemia

    • Principal Investigator
      Osone Shinya
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Study of specific gene expression in intractable childhood cancer and growth suppression and differentiation inducing effect of HDAC inhibitors

    • Principal Investigator
      Iehara Tomoko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Mutations in the RAS Pathway as Potential Precision Medicine Targets in Treatment of Rhabdomyosarcoma

    • Principal Investigator
      Kikuchi Ken
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  A novel cell and gene therapy for human rhabdomyosarcoma using exosome delivery systemPrincipal Investigator

    • Principal Investigator
      Hosoi Hajime
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of new treatment strategy for rhabdomyosarcoma using serum and cerebrospinal fluid microRNA

    • Principal Investigator
      Miyachi Mitsuru
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Elucidation of tumor immunity mechanism for clinical application of anti-PD1 antibody in childhood cancer

    • Principal Investigator
      Tsuchiya Kunihiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Study of recurrence mechanism in super high-risk neuroblastoma

    • Principal Investigator
      Tomoko Iehara
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The establishment of peptide vaccine as a consolidation therapy for childhood cancer.Principal Investigator

    • Principal Investigator
      Hosoi Hajime
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of non-invasive diagnosis and novel therapies for pediatric solid tumorPrincipal Investigator

    • Principal Investigator
      Hosoi Hajime
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pediatric surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The Epigenome Analysis of the Mechanisms of Chemoresistance and Development new treatment in Rhabdoid Tumor

    • Principal Investigator
      KUWAHARA YASUMICHI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Elucidation of mechanism underlying rhabdomyosarcoma metastasis via circulating microRNA

    • Principal Investigator
      TSUCHIYA kunihiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Tumor specific delivery of nucleic acid using patient's dendritic cell-derived exosomePrincipal Investigator

    • Principal Investigator
      HOSOI Hajime
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The development of novel diagnostics and treatment for refractory rhabdomyosarcomaPrincipal Investigator

    • Principal Investigator
      HOSOI Hajime
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatric surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Identificaction and functional analysis of a novel fusion gene in embryonal rhabdomyosarcoma

    • Principal Investigator
      TSUCHIYA Kunihiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of the treatment strategy for childhood refractory sarcoma trying to use iPS technology for possible reprogramming of cancer stem cell.

    • Principal Investigator
      MORIKAWA YASUHIDE
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pediatric surgery
    • Research Institution
      Keio University
  •  Impact of susteined expression of phox2b gene on the differentiation of neuroblastoma

    • Principal Investigator
      IEHARA Tomoko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  EVALUATION OF PROGNOSIS AND EFFICACY OF THERAPY FOR NEUROBLASTOMA PATIENTS BY QUANTIFICATION OF METHYLATED DCR2 GENE PROMOTER IN SERUM DNAPrincipal Investigator

    • Principal Investigator
      HOSOI Hajime, 杉本 徹
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Clinical trial for childhood rhabdomyosarcoma with a quality control during treatment in combination with gene analysis

    • Principal Investigator
      MORIKAWA Yasuhide
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pediatric surgery
    • Research Institution
      Keio University
  •  神経芽腫担癌患児の血清中遊離DNAを用いた細胞遺伝子学的悪性度推定法の開発Principal Investigator

    • Principal Investigator
      細井 創
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The development of the new clinical trial based on the quality assurance of treatment process in the childhood rhabdomyosarcoma.

    • Principal Investigator
      MORIKAWA Yasuhide
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pediatric surgery
    • Research Institution
      Keio University
  •  Growth, Differentiation, Survival and Apoptosis in Human Neuroblastoma Cells

    • Principal Investigator
      SUGIMOTO Tohru
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  神経芽細胞腫の骨転移メカニズム解明のための基礎的研究

    • Principal Investigator
      ARIMOTO Akiko, 澤田 淳
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  STUDY OF SIGNALTRANSDUCTION PATHWAY FOR TERMINAL DIFFERENTIATION OF RHABDOMYOSARCOMA CELLSPrincipal Investigator

    • Principal Investigator
      HOSOI Hajime, 澤田 淳
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Pediatrics
    • Research Institution
      KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
  •  Tumor-biological significance of Myc-relarted gene products in neuroblastoma cellsPrincipal Investigator

    • Principal Investigator
      HOSOI Hajime
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2021 2020 2019 2018 2017 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] Neuroblastoma2013

    • Author(s)
      Yagyu S,Iehara T,Hosoi H.
    • Publisher
      INTECH
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Book] 横紋筋肉腫. 小児疾患の診断治療基準第3版.「小児内科」「小児外科」編集員会共編.小児内科 Vol.38増刊号2006

    • Author(s)
      細井創
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-17209055
  • [Book] よく理解できる子どものがん (別所文雄、横森欣司編)2006

    • Author(s)
      杉本 徹, 家原知子, 細井 創 他
    • Publisher
      永井書店、東京
    • Data Source
      KAKENHI-PROJECT-18390300
  • [Journal Article] Development of non-viral, ligand-dependent, EPHB4-specific chimeric antigen receptor T cells for treatment of rhabdomyosarcoma2021

    • Author(s)
      Kubo H, Yagyu S, Nakamura K, Yamashima K, Tomida A, Kikuchi K, Iehara T, Nakazawa Y, Hosoi H.
    • Journal Title

      Molecular Therapy - Oncolytics

      Volume: 20 Pages: 646-658

    • DOI

      10.1016/j.omto.2021.03.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08326, KAKENHI-PROJECT-20K07641
  • [Journal Article] Inhibition of MEK pathway enhances the antitumor efficacy of chimeric antigen receptor T cells against neuroblastoma2021

    • Author(s)
      Tomida Akimasa、Yagyu Shigeki、Nakamura Kayoko、Kubo Hiroshi、Yamashima Kumiko、Nakazawa Yozo、Hosoi Hajime、Iehara Tomoko
    • Journal Title

      Cancer Science

      Volume: 112 Pages: 4026-4036

    • DOI

      10.1111/cas.15074

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08326, KAKENHI-PROJECT-20K07641
  • [Journal Article] Successful treatment with 2-chlorodeoxyadenosine of refractory pediatric Langerhans cell histiocytosis with initial involvement of the gastrointestinal tract2019

    • Author(s)
      Azusa Mayumi, Toshihiko Imamura, Kenichi Sakamoto, Takeshi Ota, Shinya Osone, Ikuya Usami, Hajime Hosoi
    • Journal Title

      International Journal of Hematology

      Volume: 110 Pages: 756-762

    • DOI

      10.1007/s12185-019-02711-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08326
  • [Journal Article] Disordered hemostasis associated with severely depressed fibrinolysis demonstrated using a simultaneous thrombin and plasmin generation assay during L‐asparaginase induction therapy in pediatric acute lymphoblastic leukemia2019

    • Author(s)
      Ishihara Takashi、Nogami Keiji、Ochi Satoshi、Ishida Toshiaki、Kosaka Yoshiyuki、Sawada Akihisa、Inoue Masami、Osone Shinya、Imamura Toshihiko、Hosoi Hajime、Shima Midori
    • Journal Title

      Pediatric Blood & Cancer

      Volume: 67

    • DOI

      10.1002/pbc.28016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08304, KAKENHI-PROJECT-19K08326
  • [Journal Article] OBP-801, a novel histone deacetylase inhibitor, induces M phase arrest and apoptosis in rhabdomyosarcoma cells.2019

    • Author(s)
      Tomoyasu C, Kikuchi K, Kaneda D, Yagyu S, Miyachi M, Tsuchiya K, Iehara T, Sakai T, Hosoi H.
    • Journal Title

      Oncol Rep.

      Volume: 41 Pages: 643-649

    • DOI

      10.3892/or.2019.6997

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Journal Article] OBP801, a novel histone deacetylase inhibitor, induces M?phase arrest and apoptosis in rhabdomyosarcoma cells2019

    • Author(s)
      Tomoyasu C, Kikuchi K, Kaneda D, Yagyu S, Miyachi M, Tsuchiya K, Iehara T, Sakai T, Hosoi H
    • Journal Title

      Oncology Reports

      Volume: 41(1) Pages: 643-649

    • DOI

      10.3892/or.2018.6813

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10122
  • [Journal Article] Mutations in the RAS pathway as potential precision medicine targets in treatment of rhabdomyosarcoma2019

    • Author(s)
      Nakagawa N, Kikuchi K, Yagyu S, Miyachi M, Iehara T, Tajiri T, Sakai T, Hosoi H.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 512 Pages: 524-530

    • DOI

      10.1016/j.bbrc.2019.03.038

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10123, KAKENHI-PROJECT-17H04230, KAKENHI-PROJECT-19K09053, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03719, KAKENHI-PROJECT-17K11517, KAKENHI-PROJECT-17K11518
  • [Journal Article] Identification of a novel BOC-PLAG1 fusion gene in a case of lipoblastoma.2019

    • Author(s)
      Nitta Y, Miyachi M, Tomida A, Sugimoto Y, Nakagawa N, Yoshida H, Ouchi K, Tsuchiya K, Iehara T, Konishi E, Umeda K, Okamoto T, Hosoi H.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 512 Pages: 49-52

    • DOI

      10.1016/j.bbrc.2019.02.154

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Journal Article] 日米欧における横紋筋肉腫のトランスレーショナルリサーチ~小児がん治療医の視点から2019

    • Author(s)
      宮地 充、細井 創.
    • Journal Title

      Journal of Kyoto Prefectural University of Medicine

      Volume: 128 Issue: 2 Pages: 115-125

    • DOI

      10.32206/jkpum.128.02.115

    • ISSN
      0023-6012
    • Language
      Japanese
    • Open Access
    • Data Source
      KAKENHI-PROJECT-16K10035
  • [Journal Article] Cellular and molecular characteristics of established neuroblastoma cell lines.2019

    • Author(s)
      Tohru Sugimoto, Hiroshi Kuroda, Sigeki Yagyu, Takahiro Gotoh, Shinya Osone, Shinchi Tamura, Tomoko Iehara, Hajime Hosoi
    • Journal Title

      Journal of Cancer Research and Therapeutic Oncology

      Volume: 7 Pages: 1-15

    • DOI

      10.17303/jcrto.2019.7.201

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08326
  • [Journal Article] Validity of image-defined risk factors in localized neuroblastoma: A report from two centers in Western Japan.2015

    • Author(s)
      Fumino S, Kimura K, Iehara T, Nishimura M, Nakamura S, Souzaki R, Nishie A, Taguchi T, Hosoi H, Tajiri T
    • Journal Title

      J Pediatr Surg

      Volume: 50 Pages: 2012-2106

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Journal Article] Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma.2015

    • Author(s)
      34.Seki M, Nishimura R, Yoshida K, Shimamura T, Shiraishi Y, Sato Y, Kato M, Chiba K, Tanaka H, Hoshino N, Nagae G, Shiozawa Y, Okuno Y, Hosoi H, Tanaka Y, Okita H, Miyachi M, Souzaki R, Taguchi T, Koh K, Hanada R, Kato K, Nomura Y, Akiyama M, Oka A, Igarashi T, Miyano S, Aburatani H, Hayashi Y, Ogawa S, Takita J
    • Journal Title

      Nat. Commun.

      Volume: 3 Pages: 7557-7557

    • NAID

      120005623266

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Journal Article] A NOXA/MCL-1 Imbalance Underlies Chemoresistance of Malignant Rhabdoid Tumor Cells.2015

    • Author(s)
      Ouchi K, Kuwahara Y, Iehara T, Miyachi M, Katsumi Y, Tsuchiya K, Konishi E, Yanagisawa A, Hosoi H.
    • Journal Title

      J Cell Physiol.

      Volume: 9999 Pages: 1-9

    • DOI

      10.1002/jcp.25293

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461602
  • [Journal Article] Identification of a homozygous JAK3 V674A mutation caused by acquired uniparental disomy in a relapsed early T-cell precursor ALL patient2015

    • Author(s)
      42.Kawashima-Goto S, Imamura T, Seki M, Kato M, Yoshida K, Sugimoto A, Kaneda D, Fujiki A, Miyachi M, Nakatani T, Osone S, Ishida H, Taki T, Takita J, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Hosoi H
    • Journal Title

      Int J Hematol.

      Volume: 101 Pages: 411-416

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Journal Article] PAX3-NCOA2 fusion gene has a dual role in promoting the proliferation and inhibiting the myogenic differentiation of rhabdomyosarcoma cells.2014

    • Author(s)
      Yoshida H, Miyachi M, Hosoi H, et al
    • Journal Title

      Oncogene.

      Volume: 11(印刷中) Pages: 5601-8

    • DOI

      10.1038/onc.2013.491

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-21249085, KAKENHI-PROJECT-23590464, KAKENHI-PROJECT-24659500, KAKENHI-PROJECT-24791078, KAKENHI-PROJECT-25253095
  • [Journal Article] Identification of COL3A1 and RAB2A as novel translocation partner genes of PLAG1 in lipoblastoma2014

    • Author(s)
      Yoshida H, Miyachi M, Tsuchiya K, Iehara T, Hosoi H, et al.
    • Journal Title

      Genes Chromosomes Cancer

      Volume: 53(7) Pages: 606-11

    • Data Source
      KAKENHI-PROJECT-24659500
  • [Journal Article] Identification of COL3A1 and RAB2A as novel translocation partner genes of PLAG1 in lipoblastoma2014

    • Author(s)
      Yoshida H, Miyachi M, Ouchi K, Kuwahara Y, Tsuchiya K, Iehara T, Konishi E, Yanagisawa A, Hosoi H
    • Journal Title

      Genes Chromosomes Cancer.

      Volume: 印刷中 Pages: 606-611

    • DOI

      10.1002/gcc.22170

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Journal Article] Ewing Sarcoma Arising After Treatment of Diffuse Large B-cell Lymphoma.2013

    • Author(s)
      Hiramoto N, Kobayashi Y, Nomoto J, Maruyama D, Watanabe T, Tochigi N, Furuta K, Takeda K, Chuman H, Yagyu S, Hosoi H, Tobinai K.
    • Journal Title

      Jpn J Clin Oncol.

      Volume: 43(4) Pages: 417-21

    • DOI

      10.1093/jjco/hyt011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25253095, KAKENHI-PROJECT-25461442
  • [Journal Article] Successful treatment of infants with localized neuroblastoma based on their MYCN status.2013

    • Author(s)
      Iehara T, Hamazaki M, Tajiri T, Kawano Y, Kaneko M, Ikeda H, Hosoi H, Sugimoto T, Sawada T
    • Journal Title

      Int J Clin Oncol.

      Volume: 18(3) Pages: 389-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Journal Article] A MYCN-amplified cell line derived from a long-term event-free survivor among our sixteen established neuroblastoma cell lines.2013

    • Author(s)
      Sugimoto T, Gotoh T, Yagyu S, Kuroda H, Iehara T, Hosoi H, Ohta S, Ohira M, Nakagawara A.
    • Journal Title

      Cancer Lett.

      Volume: 331 Pages: 115-121

    • DOI

      10.1016/j.canlet.2012.12.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591562, KAKENHI-PROJECT-24249061, KAKENHI-PROJECT-25253095
  • [Journal Article] Quantitative RT-PCR analysis of the MOZ-CBP fusion transcript in therapy-related acute myeloid leukemia with t(8;16)(p11;p13)2012

    • Author(s)
      Fujiki A, Tsuchiya K, Iehara T, Hosoi H, et al
    • Journal Title

      J Pediatr Hematol Oncol

      Volume: 34(5) Pages: 402-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Journal Article] Quantitative RT-PCR analysis of the MOZ-CBP fusion transcript in therapy-related acute myeloid leukemia with t(8;16)(p11;p13)2012

    • Author(s)
      Fujiki A, Tsuchiya K, Iehara T, Hosoi H, et al
    • Journal Title

      J Pediatr Hematol Oncol

      Volume: 34(5) Pages: 402-5

    • Data Source
      KAKENHI-PROJECT-22591166
  • [Journal Article] Post-transcriptional modulation of C/EBPα prompts monocytic differentiation and apoptosis in acute myelomonocytic leukaemia cells2012

    • Author(s)
      Yoshida H, Hosoi H, et al
    • Journal Title

      Leuk Res

      Volume: 36(6) Pages: 735-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Journal Article] Sensitivity of malignant rhabdoid tumor cell lines to PD 0332991 is inversely correlated with p16 expression2011

    • Author(s)
      Katsumi Y, Iehara T, Tsuchiya K, Hosoi H, et al
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 413(1) Pages: 62-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Journal Article] Sensitivity of malignant rhabdoid tumor cell lines to PD 0332991 is inversely correlated with p16 expression2011

    • Author(s)
      Katsumi Y, Iehara T, Tsuchiya K, Hosoi H, et al
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 413(1) Pages: 62-8

    • Data Source
      KAKENHI-PROJECT-22591166
  • [Journal Article] Preoperative analysis of 11q loss using circulating tumor-released DNA in serum: a novel diagnostic tool for therapy stratification of neuroblastoma2011

    • Author(s)
      Yagyu S, Iehara T, Tsuchiya K, Hosoi H, et al
    • Journal Title

      Cancer Lett

      Volume: 309(2) Pages: 185-9

    • Data Source
      KAKENHI-PROJECT-22591166
  • [Journal Article] Preoperative analysis of 11q loss using circulating tumor-released DNA in serum: a novel diagnostic tool for therapy stratification of neuroblastoma2011

    • Author(s)
      Yagyu S, Iehara T, Tsuchiya K, Hosoi H, et al
    • Journal Title

      Cancer Lett

      Volume: 309(2) Pages: 185-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Journal Article] Circulating musclespecific microRNA, miR-206, as a potential diagnostic marker for rhabdomyosarcoma2010

    • Author(s)
      Miyachi M, Tsuchiya K, Iehara T, Hosoi H, et al
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 400(1) Pages: 89-93

    • Data Source
      KAKENHI-PROJECT-22591166
  • [Journal Article] Circulating muscle-specific microRNA, miR-206, as a potential diagnostic marker for rhabdomyosarcoma2010

    • Author(s)
      Miyachi M, Hosoi H. et al
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 400 Pages: 89-93

    • DOI

      10.1016/j.bbrc.2010.08.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Journal Article] Circulating muscle-specific microRNA, miR-206, as a potential diagnostic marker for rhabdomyosarcoma.2010

    • Author(s)
      Miyachi M, Hosoi H., et al
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 400 Pages: 89-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Journal Article] Circulating muscle-specific microRNA, miR-206, as a potential diagnostic marker for rhabdomyosarcoma2010

    • Author(s)
      Miyachi M, Tsuchiya K, Hosoi H, et al.
    • Journal Title

      Biochemical and Biophysics Research Communications

      Volume: 400 Pages: 89-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Journal Article] Circulating muscle-specific microRNA, miR-206, as a potential diagnostic marker for rhabdomyosarcoma2010

    • Author(s)
      Miyachi M, Tsuchiya K, Iehara T, Hosoi H, et al
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 400(1) Pages: 89-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Journal Article] Restoration of p53 pathway by nutlin-3 induces cell cycle arrest and apoptosis in human rhabdomyosarcoma cells2009

    • Author(s)
      Miyachi M, Kakazu N, Hosoi H, et al.
    • Journal Title

      Clin Cancer Res. 15

      Pages: 4077-4084

    • Data Source
      KAKENHI-PROJECT-21249085
  • [Journal Article] Lysosomal-associated protein multispanning transmembrane 5 gene(LAPTM5)is associated with spontaneous regression of neuroblastomas2009

    • Author(s)
      Inoue J, Misawa A, Hosoi H, et al.
    • Journal Title

      PLoS One 29

    • Data Source
      KAKENHI-PROJECT-21249085
  • [Journal Article] A novel PAX3 rearrangement in embryonal rhabdomyosarcoma.2009

    • Author(s)
      Hosoi H, et al.
    • Journal Title

      Cancer Genet Cytogenet. 189

      Pages: 98-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209055
  • [Journal Article] Restoration of p53 pathway by nutlin-3 induces cell cycle arrest and apoptosis in human rhabdomyosarcoma cells2009

    • Author(s)
      Miyachi M, Kakazu N, Hosoi H, et al
    • Journal Title

      Clin Cancer res

      Volume: 15 Pages: 4077-4084

    • DOI

      10.1158/1078-0432.ccr-08-2955

    • Data Source
      KAKENHI-PROJECT-21249085
  • [Journal Article] A novel PAX3 rearrangement in embryonal rhabdomyosarcoma2009

    • Author(s)
      Hosoi H, Kakazu N, Konishi E, (他18名)
    • Journal Title

      Cancer Genet Cytogenet 189(2)

      Pages: 98-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209055
  • [Journal Article] Trastuzumab Activates Allogeneic or Autologous Antibody-Dependent Cellular Cytotoxicity against Malignant Rhabdoid Tumor Cells and Interleukin-2 Augments the Cytotoxicity2008

    • Author(s)
      Katsumi Y, Tsuchiya K, Iehara T, Hosoi H, et.al.
    • Journal Title

      Clin Cancer Res 14

      Pages: 1192-1199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591262
  • [Journal Article] Effects of PAX3-FKHR on malignant phenotypes in alveolar rhabdomyosarcoma2008

    • Author(s)
      Kikuchi K, Tsuchiya K, Iehara T, Hosoi H, et.al.
    • Journal Title

      Biochem Biophys Res Commun 365

      Pages: 568-574

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591262
  • [Journal Article] Late appearance of a Philadelphia chromosome in a patient with. therapy-related acute myeloid leukemia and high expression of EVI12008

    • Author(s)
      Yagyu S, Iehara T, Hosoi H, et.al.
    • Journal Title

      Cancer Genetics and Cytogenetics 182(2)

      Pages: 115-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591262
  • [Journal Article] Induction of apoptosis by an inhibitor of EGFR in neuroblastoma cells2007

    • Author(s)
      Tamura S, Hosoi H, et. al.
    • Journal Title

      Biochem Biophys Res Commun 358

      Pages: 226-232

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390300
  • [Journal Article] A review of 331 rhabdomyosarcoma cases in patients treated between 1991 and 2002 in Japan2007

    • Author(s)
      10.Hosoi H, Teramukai S, Matsumoto Y, Tsuchiya K, Iehara T, Hara J, Mitsui T, Kaneko M, Hatae Y, Hayashi Y, Mabuchi O, Adachi N, Morikawa Y., (他5名)
    • Journal Title

      Int J Clin Oncol 12(2)

      Pages: 137-145

    • NAID

      10019496687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209055
  • [Journal Article] Insulin-like growth factor-I has different effects on myogenin induction and cell cycle progression in human alveolar and embryonal rhabdomyosarcoma cells2007

    • Author(s)
      12.Tsuchiya K, Hosoi H, Misawa-Furihata A, Houghton PJ, Sugimoto T
    • Journal Title

      Int J Oncol 31

      Pages: 41-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209055
  • [Journal Article] Epigenetic silencing of prostaglandin E receptor 2 (PTGER2)is associated with progression of neuroblastomas2007

    • Author(s)
      Sugino Y, Hosoi H, et. al.
    • Journal Title

      Oncogene 26

      Pages: 7401-7413

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390300
  • [Journal Article] Induction of apoptosis by an inhibitor of EGFR in neuroblastoma cells2007

    • Author(s)
      Tamura, S, Hosoi, H, et. al.
    • Journal Title

      Biochem Biophys Res Commun 358

      Pages: 226-232

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390300
  • [Journal Article] Epigenetic silencing of prostaglandin E receptor 2(PTGER2)is associated with progression of neuroblastomas2007

    • Author(s)
      Sugino Y, Hosoi H, et. al.
    • Journal Title

      Oncogene 26

      Pages: 7401-7413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390300
  • [Journal Article] Induction of apoptosis by an inhibitor of EGFR in neuroblastoma cells.2007

    • Author(s)
      Tamura S, Hosoi H, et. al.
    • Journal Title

      Biochem Biophys Res Commun 358

      Pages: 226-232

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390300
  • [Journal Article] Insulin-like growth factor-I has different effects on myogenin induction and cell cycle progression in human alveolar and embryonal rhabdomyo sarcoma cells.2007

    • Author(s)
      Tsuchiya K, Hosoi H, et. al.
    • Journal Title

      Int J Oncol 31

      Pages: 41-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209055
  • [Journal Article] Epigenetic silencing of prostaglandin E receptor 2 (PTGER2) is associated with progression of neuroblastomas2007

    • Author(s)
      Sugino, Y, Hosoi, H, et. al.
    • Journal Title

      Oncogene 26

      Pages: 7401-7413

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390300
  • [Journal Article] A review of 331 rhabdomyosarcoma cases in patients treated between 1991 and 2002 in Japan.2007

    • Author(s)
      Hosoi H, Morikawa Y, et. al.
    • Journal Title

      Int J Clin Oncol 12

      Pages: 137-145

    • NAID

      10019496687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209055
  • [Journal Article] MYCN gene amplification is a powerful prognostic factor even in infantile neuroblastoma detected by mass screening.2006

    • Author(s)
      Iehara T, Hosoi H, Sugimoto T, et al.
    • Journal Title

      Br J Cancer. 94(10)

      Pages: 1510-5

    • Data Source
      KAKENHI-PROJECT-18390300
  • [Journal Article] ERK2 phosphorylation is crucial for motility of human alveolar rhabdomyosarcoma cells stimulated by hepatocyte growth factor.2006

    • Author(s)
      Oatabe O, Hosoi H, et al.
    • Journal Title

      Pediatr Blood Cancer. 47(1)

      Pages: 418-418

    • Data Source
      KAKENHI-PROJECT-17209055
  • [Journal Article] Quantative real-time reverse-transcription polymerase chain reaction for diagnosis of PAX3-FKHR positive alveolar rhabdomyosarcoma.2006

    • Author(s)
      Hosoi H, et al.
    • Journal Title

      Pediatr Blood Cancer. 47(1)

      Pages: 414-414

    • Data Source
      KAKENHI-PROJECT-17209055
  • [Journal Article] Clinical trial of photodynamic therapy using acridine orange with/without low dose radiation as new limb salvage modality in musculoskeletal sarcomas2005

    • Author(s)
      26.Kusuzaki K, Murata H, Matsubara T, Miyazaki S, Okamura A, Seto M, Matsumine A, Hosoi H, Sugimoto T, Uchida A
    • Journal Title

      Anticancer Res 25

      Pages: 1225-1236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209055
  • [Journal Article] Prediction of MYCN Amplification in Neuroblastoma Using Serum DNA and Real-time Quantitative Polymerase Reaction.2005

    • Author(s)
      Gotoh T, Hosoi H, Iehara T, et al.
    • Journal Title

      Journal of Clinical Oncology 23(22)

      Pages: 5205-5210

    • Data Source
      KAKENHI-PROJECT-15659248
  • [Journal Article] Fenretinide induces sustained-activation of JNK/p38 MAPK and apoptosis ina reactive oxygen species-dependent manner in nueroblastoma cells.2004

    • Author(s)
      Osono S, Hosoi H, Kuwahara Y et al.
    • Journal Title

      Int J Cancer 112(2)

      Pages: 219-224

    • Data Source
      KAKENHI-PROJECT-14207071
  • [Journal Article] Antitumor activity of gefitinib in malignant rhabdoid tumor cells in vitro and in vivo2004

    • Author(s)
      Kuwahara Y, Hosoi H, Osone S et al.
    • Journal Title

      Clin Cancer Res 10(17)

      Pages: 5940-5948

    • Data Source
      KAKENHI-PROJECT-14207071
  • [Journal Article] 横紋筋肉腫に対する治療プロトコール 化学療法レジメンと放射線治療および外科治療ガイドライン2004

    • Author(s)
      森川康英, 土田嘉昭, 原純一, 太田茂, 細井創, 池田均 ほか
    • Journal Title

      小児外科 36(7)

      Pages: 939-946

    • Data Source
      KAKENHI-PROJECT-14207071
  • [Journal Article] Regression of refractory rhabdomyosarcoma after allogeneic stem-cell transplantation.2003

    • Author(s)
      Misawa A, Hosoi H et al.
    • Journal Title

      Pediatr Hematol Oncol. 20(2)

      Pages: 151-155

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207071
  • [Patent] 体液由来検体を用いた横紋筋肉腫の検出方法2011

    • Inventor(s)
      細井創、宮地充
    • Industrial Property Rights Holder
      京都府公立大学法人
    • Filing Date
      2011-04-07
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Patent] 体液由来検体を用いた横紋筋肉腫の検出方法2011

    • Inventor(s)
      宮地 充、細井 創
    • Industrial Property Rights Holder
      京都府公立大学法人、LSIP LLC
    • Filing Date
      2011-04-07
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Patent] 血液由来検体を用いた横紋筋肉腫の検出方法2010

    • Inventor(s)
      細井創、宮地充
    • Industrial Property Number
      2010-089180
    • Filing Date
      2010-04-08
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] Combination therapy of GD2-specific CAR-T cell with Tyrosine Kinase inhibitor for neuroblastoma cells.2020

    • Author(s)
      Tomida A, Yagyu S, Yamashima K, Kubo H, Iehara T, Nakazawa Y, Hosoi H.
    • Organizer
      23rd Annual Meeting of American Society of Gene and Cell Therapy.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08326
  • [Presentation] Optimization of PiggyBac Transposon-Based Gene Delivery by the MaxCyte Scalable Transfection System for Manufacturing Chimeric Antigen Receptor-T Cells.2019

    • Author(s)
      Tomida A, Yagyu S, Yamashima K, Kubo H, Iehara T, Nakazawa Y, Hosoi H.
    • Organizer
      22nd Annual Meeting of American Society of Gene and Cell Therapy
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] Development of PiggyBac Transposon Mediated CAR-T Cells Targeting EPHB4 for Pediatric Solid Tumors.2019

    • Author(s)
      Yagyu S, Tomida A, Kubo H, Yamashima K, Kikuchi K, Nakamura K, Tanaka M, Nakazawa Y, Iehara T, Hosoi H.
    • Organizer
      51st Annual Congress of the International Society of Paediatric Oncology
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] 類白血病反応を伴った1型高IgE症候群の乳児例2019

    • Author(s)
      野田佳奈子,今村俊彦,大曽根眞也,岡本圭祐,井澤和司,金兼弘和,牧野 茂,今宿晋作,細井 創
    • Organizer
      第61回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08326
  • [Presentation] トランスポゾン法で作成したGD2特異的CART細胞は神経芽腫細胞に対して抗腫瘍効果を示す.Development of piggyBac Transposon-Mediated GD2 specific CAR-T Cells targeting Neuroblastoma.2019

    • Author(s)
      Tomida A, Yagyu S, Yamashima K, Yoshida H, Miyachi M, Tsuchiya K, Iehara T, Nakazawa Y, Hosoi H.
    • Organizer
      第61回日本小児血液・がん学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] 再発B前駆細胞型急性リンパ性白血病のクローン進化の検討2019

    • Author(s)
      眞弓あずさ,今村俊彦,飯島友加,冨井敏宏,西島 大,友安千紘,矢野未央,田村真一,大曽根眞也,石田宏之,白石友一,黒田啓史,宮野 悟,堀部敬三,小川誠治,眞田 昌,細井 創
    • Organizer
      第122回日本小児科学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08326
  • [Presentation] 小児がん拠点病院である当院における終末期在宅医療の現状2019

    • Author(s)
      宮地 充,柳生茂希,大曽根眞也,土屋邦彦,今村俊彦,家原知子,細井 創
    • Organizer
      第57回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08326
  • [Presentation] Development of chimeric antigen receptor T cell therapy for human rhabdomypsarcoma.2019

    • Author(s)
      Yagyu S, Morita D, Tanaka M, Kikuchi K, Iehara T, Nakazawa Y, Hosoi H
    • Organizer
      The 2nd International Cancer Research Symposium of Training Plan for Oncology Professionals.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] BRCA1とMLH1の胚細胞変異を有する急性巨核芽球性白血病(AMKL)の1例2019

    • Author(s)
      末松正也,今村俊彦,大曽根眞也,堂 淳子,吉田仁典,加藤元博,細井 創
    • Organizer
      第61回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08326
  • [Presentation] FANCI遺伝子変異が同定された乳児期発症ファンコニ―貧血の1例2019

    • Author(s)
      浦田貴代,今村俊彦,大曽根眞也,村松秀城,高橋義行,細井 創
    • Organizer
      第61回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08326
  • [Presentation] 横紋筋肉腫の標準的治療とわが国の臨床研究の現況2019

    • Author(s)
      細井 創
    • Organizer
      第2回日本サルコーマ治療研究学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] 日本横紋筋肉腫研究グループ第1期臨床試験の結果と第2期臨床試験の戦略.2018

    • Author(s)
      細井 創
    • Organizer
      第60回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] 横紋筋肉腫に対する新規 RAF/MEK デュアル阻害剤の検討2018

    • Author(s)
      Nakagawa N, Kikuchi K, Yagyu S, Iehara T, Sakai T, Hosoi H.
    • Organizer
      第60回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] The novel histone deacetylase inhibitor OBP-801 induces apoptosis in neuroblastoma tumor cells2018

    • Author(s)
      Daisuke Kaneda, Ken Kikuchi, Kayoko Nakamura, Shigeki Yagyu, Tomoko Iehara, Toshiyuki Sakai, Hajime Hosoi
    • Organizer
      Advances in NEうろbぁs苫Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10122
  • [Presentation] 横紋筋肉腫における新規ヒストン脱アセチル化酸素阻害剤OBP-801の抗腫瘍効果.2018

    • Author(s)
      菊地顕,友安千紘,中村加世子,柳生茂希,宮地充,勝見良樹,土屋邦彦,家原知子,酒井敏行,細井 創
    • Organizer
      第121回日本小児科学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] 横紋筋肉腫に対する新たな治療戦略2018

    • Author(s)
      Kikuchi K, Hosoi H
    • Organizer
      第60回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] The novel histone deacetylase inhibitor OBP-801 induces apoptosis in neuroblastoma tumor cells2018

    • Author(s)
      Daisuke Kaneda, Ken Kikuchi, Kayoko Nakamura, Shigeki Yagyu, Tomoko Iehara, Toshiyuki Sakai, Hajime Hosoi
    • Organizer
      Advances in Neuroblastoma research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10122
  • [Presentation] 成人鼻副鼻腔横紋筋肉腫4症例の治療経験.2018

    • Author(s)
      安田 誠, 呉本年弘, 村上賢太郎, 乾 隆昭, 大江絵里, 宮地 充, 土屋邦彦, 家原知子, 細井 創, 平野 滋.
    • Organizer
      第57回日本鼻科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] 横紋筋肉腫における新規ヒストン脱アセチル化酸素阻害剤OBP-801の抗腫瘍効果2018

    • Author(s)
      菊地顕,友安千紘,中村加世子,柳生茂希,宮地充,勝見良樹,土屋邦彦,家原知子,酒井敏行,細井 創
    • Organizer
      第121回日本小児科学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10122
  • [Presentation] 横紋筋肉腫における新規ヒストン脱メチル化酵素阻害剤の抗腫瘍効果と分子機構の解析2018

    • Author(s)
      菊地顕、友安千紘、中村加世子、柳生茂希、宮地充、家原知子、酒井敏行、細井創
    • Organizer
      第121回日本小児科学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10122
  • [Presentation] Novel allosteric RAF/MEK inhibitor in the treatment of rhabdomyosarooma.2018

    • Author(s)
      Nakagawa N, Kikuchi K, Yagyu S, Iehara T, Sakai T, Hosoi H.
    • Organizer
      第60回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10123
  • [Presentation] Chimeric Antigen Receptor T cells redirecting EPHB4 for the Treatment of Human Rhabdomyosarcoma.2017

    • Author(s)
      Nakamura K,Yagyu S,Morita D,Kikuchi K,Iehara T,Hosoi H,Nakazawa Y.
    • Organizer
      第2回日本遺伝子細胞治療学会若手研究会
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] Mutation of Ras Pathway Should be a Target of Precision Medicine for Rhabdomyosarcoma2017

    • Author(s)
      N. nakagawa, K. Kikuchi, K. Nakamura, T. Tanaka, S. Yagyu, T. Iehara, T. Tajiri, T. Sakai, H. Hosoi
    • Organizer
      49th CONGRESS OF THE INTERNATIONAL SOCIETY OF PAEDIATRIC ONCOLOGY (SIOP)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10123
  • [Presentation] Chimeric Antigen Receptor T cells redirecting EPHB4 for the Treatment of Human Rhabdomyosarcoma.2017

    • Author(s)
      Yagyu S,Nakamura K,Morita D,Kikuchi K,Iehara T,Hosoi H,Nakazawa Y.
    • Organizer
      第23回日本遺伝子細胞治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] Chimeric Antigen Receptor T cells redirecting EPHB4 for the Treatment of Human Rhabdomyosarcoma.2017

    • Author(s)
      Yagyu S,Nakamura K,Morita D,Kikuchi K,Iehara T,Hosoi H,Nakazawa Y.
    • Organizer
      第59回日本小児血液がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04230
  • [Presentation] 胞巣型横紋筋肉腫細胞株Rh30において、PAX3-FOXO1ノックダウンはPDL1発現を低下させる.2015

    • Author(s)
      新田義宏、宮地充、大内一孝、吉田秀樹、土屋邦彦、桒原康通、家原知子、細井創.
    • Organizer
      第57回小児血液・がん学会学術集会.
    • Place of Presentation
      甲府
    • Year and Date
      2015-11-26
    • Data Source
      KAKENHI-PROJECT-26670508
  • [Presentation] Loss of NOXA expression by INI1/SNF5 loss impaired sensitivity to chemotherapeutic agents in malignant rhabdoid tumor in vitro and iv vivo.2015

    • Author(s)
      Ouchi K, Kuwahara Y, Iehara T, Konishi E, Hosoi H.
    • Organizer
      106th American Association for Cancer Research Annual Meeting.
    • Place of Presentation
      Philadelphia, PA,U.S.A.
    • Year and Date
      2015-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461602
  • [Presentation] Diagnostic and prognostic role of circulating miR-206 in rhabdomyosarcoma patients.2015

    • Author(s)
      Miyachi M, Tsuchiya K, Nitta Y, Ohuchi K, Yoshida H, Kikuchi K, Kuwahara Y, Iehara T, Hosoi H.
    • Organizer
      2015 American Society of Clinical Oncology annual meeting.
    • Place of Presentation
      シカゴ、アメリカ
    • Year and Date
      2015-05-29
    • Data Source
      KAKENHI-PROJECT-25461603
  • [Presentation] Serum miR-206 as novel biomarker for rhabdomyosarcoma.2014

    • Author(s)
      Hosoi H.
    • Organizer
      National Cancer Center of South Korea,
    • Place of Presentation
      Seoul,Korea
    • Year and Date
      2014-04-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] 神経芽腫マススクリーニングを考える 患者血清による腫瘍遺伝子診断を活用した乳児神経芽腫の治療.2014

    • Author(s)
      細井 創, 柳生 茂希, 家原 知子, 後藤 高弘, 杉本 徹, 澤田 淳.
    • Organizer
      第41回マス・スクリーニング学会学術集会.
    • Place of Presentation
      広島
    • Year and Date
      2014-08-22
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] Background and Project for Rhabdomyosarcoma Study in Japan.2014

    • Author(s)
      Hosoi H.
    • Organizer
      National Cancer Center of South Korea,
    • Place of Presentation
      Seoul,Korea
    • Year and Date
      2014-04-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] Circulating microRNA expression profiles identify patients with metastatic rhabdomyosarcoma.2013

    • Author(s)
      Miyachi M, Tsuchiya K, Hosoi H, et al.
    • Organizer
      第71回日本癌学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Presentation] 血清miR-206は、転移性横紋筋肉腫において高発現を示す2013

    • Author(s)
      宮地充,土屋邦彦,家原知子,細井創, 他
    • Organizer
      第55回日本小児血液・がん学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] High serum miR-206 expression levels define an aggressive rhabdomyosarcoma subtype.2013

    • Author(s)
      Mitsuru Miyachi, Kunihiko Tsuchiya, Kenichi Sakamoto, Kazutaka Ohuchi, Hideki Yoshida, Tomoko Iehara, Hajime Hosoi
    • Organizer
      45th Congress of the International Society of Pediatric Oncology
    • Place of Presentation
      Hong Kong
    • Data Source
      KAKENHI-PROJECT-25461603
  • [Presentation] High serum miR-206 expression levels define an aggressive rhabdomyosarcoma subtype2013

    • Author(s)
      Hosoi H
    • Organizer
      45th Congress of the International Society of Pediatric Oncology
    • Place of Presentation
      Hong Kong
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Presentation] 教育セッション軟部組織肉腫治療研究の現況2013

    • Author(s)
      細井創
    • Organizer
      第55回日本小児血液・がん学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] 血清miR-206は、転移性横紋筋肉腫において高発現を示す。2013

    • Author(s)
      宮地 充、土屋邦彦、坂本謙一、大内一孝、吉田秀樹、大曽根眞也、桑原康通、今村俊彦、家原知子、細井 創
    • Organizer
      第55回日本小児血液・がん学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] Circulating microRNA expression profiles identify patients with metastatic rhabdomyosarcoma2013

    • Author(s)
      Miyachi M, Miyachi M, Tsuchiya K, Iehara T, Hosoi H, et al.
    • Organizer
      第71回日本癌学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] High serum miR-206 expression levels define an aggressive rhabdomyosarcoma subtype. 45th Congress of the International Society of Pediatric Oncology2013

    • Author(s)
      Miyachi M,Tsuchiya K,Hosoi H, et al.
    • Organizer
      45th Congress of the International Society of Pediatric Oncology
    • Place of Presentation
      香港(中国)
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Presentation] 血清miR-206は、転移性横紋筋肉腫において高発現を示す2013

    • Author(s)
      宮地 充, 土屋邦彦, 細井 創, 他
    • Organizer
      第55回日本小児血液・がん学会学術集会
    • Place of Presentation
      福岡シーホーク(福岡県)
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Presentation] 血清miR-206 は,転移性横紋筋肉腫において高発現を示す2013

    • Author(s)
      細井創
    • Organizer
      第55回日本小児血液・がん学会学術集会
    • Place of Presentation
      福岡シーホーク
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Presentation] 血清miR-206は、転移性横紋筋肉腫において高発現を示す.2013

    • Author(s)
      宮地 充,土屋邦彦,大内一孝,坂本謙一,吉田秀樹,柳生茂希,家原知子,細井 創
    • Organizer
      第55回日本小児血液・がん学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] Circulating microRNA expression profiles identify patients with metastatic rhabdomyosarcoma.2013

    • Author(s)
      Mitsuru Miyachi, Kunihiko Tsuchiya, Kazutaka Ouchi, Hideki Yoshida, Yasumichi Kuwahara, Tomoko Iehara, Hajime Hosoi
    • Organizer
      第71回日本癌学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] Does the residual tumor mass in the intermediate risk neuroblastoma influence the prognosis?2013

    • Author(s)
      Iehara T,Tsuchiya K,Yagyu S,Ouchi K,Sakamoto K,Miyachi M,Katsumi Y,KuwaharaY,Tajiri T,Hosoi H.
    • Organizer
      45rd Congress of the International Society of Pediatric Oncology.
    • Place of Presentation
      Hong Kong,
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] 軟部組織肉腫治療研究の現況2013

    • Author(s)
      細井 創
    • Organizer
      第55回日本小児血液・がん学会学術集会
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] High serum miR-206 expression levels define an aggressive rhabdomyosarcoma subtype.2013

    • Author(s)
      Mitsuru Miyachi, Kunihiko Tsuchiya, Kenichi Sakamoto, Kazutaka Ohuchi, Hideki Yoshida, Tomoko Iehara, Hajime Hosoi
    • Organizer
      45th Congress of the International Society of Pediatric Oncology.
    • Place of Presentation
      Hong Kong
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] Circulating microRNA expression profiles identify patients with metastatic rhabdomyosarcoma.2013

    • Author(s)
      Mitsuru Miyachi, Kunihiko Tsuchiya, Kazutaka Ouchi, Hideki Yoshida, Yasumichi Kuwahara, Tomoko Iehara, Hajime Hosoi
    • Organizer
      第71回日本癌学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25461603
  • [Presentation] 血清miR-206は、転移性横紋筋肉腫において高発現を示す2013

    • Author(s)
      宮地 充、土屋邦彦、坂本謙一、大内一孝、吉田秀樹、大曽根眞也、桑原康通、今村俊彦、家原知子、細井 創
    • Organizer
      第55回日本小児血液・がん学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25461603
  • [Presentation] High serum mir-206 expression levels define an aggressive rhabdomyosarcoma subtype.2013

    • Author(s)
      Miyachi M,Tsuchiya K,Sakamoto K,Ouchi K,Yoshida H,Iehara T,Hosoi H.
    • Organizer
      45rd Congress of the International Society of Pediatric Oncology.
    • Place of Presentation
      Hong Kong,
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] High serum miR-206 expression levels define an aggressive rhabdomyosarcoma subtype2013

    • Author(s)
      Miyachi M, Tsuchiya K, Iehara T, Hosoi H, et al.
    • Organizer
      45th Congress of the International Society of Pediatric Oncology
    • Place of Presentation
      Hong Kong, China
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] 融合遺伝子陰性横紋筋肉腫において、HMGA2 遺伝子は増殖を促進する2012

    • Author(s)
      大内一孝,宮地 充,土屋邦彦,家原知子,細井 創
    • Organizer
      第54回日本小児血液・がん学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] 新規融合遺伝子PAX3-NCOA2 は横紋筋肉腫の造腫瘍性を促進し、分化を阻害する2012

    • Author(s)
      吉田秀樹,宮地 充,土屋邦彦,家原知子,細井 創
    • Organizer
      第54回日本小児血液・がん学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] High serum miR-206 expression levels define an aggressive rhabdomyosarcoma subtype.2012

    • Author(s)
      Miyachi M, Tsuchiya K, Yagyu S, Iehara T, Hosoi H.
    • Organizer
      第71回日本癌学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] VALIDATION OF SERUM MIR-206 EXPRESSION LEVEL AS A DIAGNOSTIC BIOMARKER FOR RHABDOMYOSARCOMA:A REPOT OF THE CHILDREN’S ONCOLOGY GROUP STUDY ARST12B1.2012

    • Author(s)
      Miyachi M,Tsuchiya K,Yagyu S,Iehara T,Skapek SX,Hawkins DS,Hosoi H
    • Organizer
      44th Congress of the International Society of Pediatric Oncology
    • Place of Presentation
      London
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] Validation of serum mir-206 expression level as a diagnostic biomarker for rhabdomyosarcoma : a report of the Children's Oncology Group study ARST12B12012

    • Author(s)
      Miyachi M, Tsuchiya K, Iehara T, Hosoi H, et al.
    • Organizer
      44th Congress of the International Society of Pediatric Oncology
    • Place of Presentation
      London, Unied Kingdom
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] Validation of serum mir-206 expression level as a diagnostic biomarker for rhabdomyosarcoma: a report of the Children's Oncology Group study ARST12B12012

    • Author(s)
      Miyachi M,Tsuchiya K,Iehara T, Hosoi H, et al
    • Organizer
      44th Congress of the International Society of Pediatric Oncology
    • Place of Presentation
      London, Unied Kingdom
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] p90 ribosomal S6 kinase 1 は横紋筋肉腫における新規分子標的となり得る2012

    • Author(s)
      坂本謙一,宮地 充,大内一孝,土屋邦彦,家原知子,細井 創
    • Organizer
      第54回日本小児血液・がん学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22591166
  • [Presentation] p90 ribosomal S6 kinase 1 は横紋筋肉腫における新規分子標的となり得る2012

    • Author(s)
      坂本謙一,宮地 充,大内一孝,土屋邦彦,家原知子,細井 創
    • Organizer
      第54回日本小児血液・がん学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] High serum miR-206 expression levels define an aggressive rhabdomyosarcoma subtype2012

    • Author(s)
      Miyachi M, Miyachi M, Tsuchiya K, Iehara T, Hosoi H, et al.
    • Organizer
      第71回日本癌学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] 胞巣型横紋筋肉腫において、血清 miR-206 は高発現を示す2012

    • Author(s)
      宮地 充,土屋邦彦,柳生茂希,今村俊彦,家原知子,細井 創
    • Organizer
      第54回日本小児血液・がん学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] VALIDATION OF SERUM MIR-206 EXPRESSION LEVEL AS A DIAGNOSTIC BIOMARKER FOR RHABDOMYOSARCOMA:A REPOT OF THE CHILDREN’S ONCOLOGY GROUP STUDY ARST12B12012

    • Author(s)
      Miyachi M,Tsuchiya K,Yagyu S,Iehara T,Stephen X Skapek,Douglas S Hawkins,Hosoi H
    • Organizer
      44th Congress of the International Society of Pediatric Oncology
    • Place of Presentation
      ロンドン(イギリス)
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Presentation] 新規融合遺伝子 PAX3-NCOA2 は横紋筋肉腫の造腫瘍性を促進し、分化を阻害する2012

    • Author(s)
      吉田秀樹,宮地 充,土屋邦彦,家原知子,細井 創
    • Organizer
      第54回日本小児血液・がん学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22591166
  • [Presentation] miRNAs as serum biomarkers for RMS.2012

    • Author(s)
      Hajime Hosoi
    • Organizer
      2012 Fall Children's Oncology Group meeting. Soft tissue sarcoma committee. Biology session.
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] miRNAs as serum biomarkers for RMS2012

    • Author(s)
      Hosoi H
    • Organizer
      2012 Fall Children's Oncology Group meeting. Soft tissue sarcoma committee. Biology session
    • Place of Presentation
      Atlanta. U.S.A
    • Year and Date
      2012-09-12
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] VALIDATIION OF SERUM MIR-206 EXPRESSION LEVEL AS A DIAGNOSTIC BIOMARKER FOR RHABDOMYOSARCOMA : A REPORT OF THE CHILDREN'S ONCOLOGY GROUP STUDY ARST12B12012

    • Author(s)
      Hosoi H
    • Organizer
      44th Congress of the International Society of Pediatric Oncology
    • Place of Presentation
      London
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Presentation] 胞巣型横紋筋肉腫において、血清miR-206は高発現を示す2012

    • Author(s)
      宮地充,土屋邦彦,家原知子,細井創, 他
    • Organizer
      第54回日本小児血液・がん学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659500
  • [Presentation] Dual role of PAX3-NCOA2 in tumorigenesis of rhabdomyosarcoma2011

    • Author(s)
      Miyachi M, Yoshida H, Tsuchiya K ,Iehara T, Hosoi H, et al
    • Organizer
      102ndAnnual Meeting of the American Association for Cancer Research
    • Place of Presentation
      Orlando, U.S.A
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] Dual role of PAX3-NCOA2 in tumorigenesis of rhabdomyosarcoma2011

    • Author(s)
      Miyachi M, Yoshida H, Tsuchiya K, Hosoi H, et al
    • Organizer
      102^<nd> Annual Meeting of the American Association for Cancer Research
    • Place of Presentation
      オーランド、アメリカ
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] Muscle-specific microRNA : a novel body fluid biomarker for diagnosis of rabdomyosarcoma2011

    • Author(s)
      Miyachi M, Tsuchiya K, IeharaT, Hosoi H, et al
    • Organizer
      43^<rd> Annual Congress of the International Society of Paediatric Oncology
    • Place of Presentation
      オークランド、ニュージーランド
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] Dual role of PAX3-NCOA2 in tumorigenesis of rhabdomyosarcoma2011

    • Author(s)
      Miyachi M, Tsuchiya K, Iehara T, Hosoi H, et al
    • Organizer
      102ndAnnual Meeting of the American Association for Cancer Research
    • Place of Presentation
      Orlando, U.S.A
    • Data Source
      KAKENHI-PROJECT-22591166
  • [Presentation] Muscle-specific microRNA : a novel body fluid biomarker for diagnosis of rabdomyosarcoma2011

    • Author(s)
      Miyachi M, Tsuchiya K, Hosoi H, et al
    • Organizer
      43^<rd> Annual Congress of the International Society of Paediatric Oncology
    • Place of Presentation
      Auckland, N.Z.
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Presentation] Muscle-specific micro RNA : a novel body fluid biomarker for diagnosis of rabdomyosarcoma2011

    • Author(s)
      Hosoi H
    • Organizer
      43rd Annual Congress of the International Society of Paediatric Oncology
    • Place of Presentation
      Auckland, N. Z
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Presentation] Muscle specific microRNAs : novel potential biomarkers for diagnosis of rhabdomyosarcoma.2010

    • Author(s)
      Miyachi M, Tsuchiya K, Hosoi H, et al.
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪府、大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] Muscle specific microRNAs as novel biomarkers for rhabdomyosarcoma.2010

    • Author(s)
      Miyachi M, Tsuchiya K, Hosoi H, et al.
    • Organizer
      42^<nd> Annual Congress of the International Society of Paediatric Oncology.
    • Place of Presentation
      ボストン、アメリカ
    • Data Source
      KAKENHI-PROJECT-22390329
  • [Presentation] EVALUATION OF PROGNOSIS AND EFFICACY OF THERAPY FOR NEUROBLASTOMA PATIENTS BY QUANTIFICATION OF METHYLATED DCR2 GENE PROMOTER IN SERUM DNA2008

    • Author(s)
      Yagyu S, Hosoi H, et. al.
    • Organizer
      44th Annual Meeting of American Society of Clinical Oncology
    • Place of Presentation
      Chicago,IL,USA
    • Year and Date
      2008-06-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390300
  • [Presentation] MYCN amplification contributes to dysfunction of the p53 pathway in neuroblastoma2008

    • Author(s)
      Shinichi Tamura, Tomoko Iehara, Hajime Hosoi, et.al.
    • Organizer
      Advances in Neuroblastoma Research 2008
    • Place of Presentation
      Japan Chiba
    • Data Source
      KAKENHI-PROJECT-19591262
  • [Presentation] Detection of IGF2 and H19 imprinting abnormalities in rhabdomyosarcoma patients using tumor and serum DNA2008

    • Author(s)
      Ken Kikuchi, Tomoko Iehara, Hajime Hosoi
    • Organizer
      40th International Society of Pediatric Oncology
    • Place of Presentation
      Berlin, German
    • Data Source
      KAKENHI-PROJECT-19591262
  • [Presentation] IS THE PROGNOSIS OF STAGE 4S NEUROBLASTOMA OF 12 MONTHS OLD AND OVER REALY EXCELENT?2008

    • Author(s)
      Tomoko Iehara, Hajime Hosoi, et.al.
    • Organizer
      40th International Society of Pediatric Oncology
    • Place of Presentation
      Berlin, German
    • Data Source
      KAKENHI-PROJECT-19591262
  • [Presentation] Methylation Analysis of DCR2 gene Using Tumor and Serum DNA of Neuroblastoma Patients2008

    • Author(s)
      Shigeki Yagyu, Tomoko Iehara, Hajime Hosoi, et.al.
    • Organizer
      44th annual meeting of American Society of Clinical Oncology
    • Place of Presentation
      Chicago
    • Data Source
      KAKENHI-PROJECT-19591262
  • [Presentation] EVALUATION OF PROGNOSIS AND EFFICACY OF THERAPY FOR NEUROBLASTOMA PATIENTS BY QUANTIFICATION OF METHYLATED DCR2 GENE PROMOTER IN SERUM DNA2008

    • Author(s)
      Shigeki Yagyu, Tomoko Iehara, Hajime Hosoi, et.al.
    • Organizer
      40th International Society of Pediatric Oncology
    • Place of Presentation
      Berlin, German
    • Data Source
      KAKENHI-PROJECT-19591262
  • [Presentation] EVALUATION OF PROGNOSIS AND EFFICACY OF THERAPY FOR NEUROBLASTOMA PATIENTS BY QUANTIFICATION OF METHYLATED DCR2 GENE PROMOTER IN SERUM DNA2008

    • Author(s)
      Yagyu, S, Hosoi, H, et. al.
    • Organizer
      44th Annual Meeting of American Society of Clinical Oncology ld
    • Place of Presentation
      Chicago, IL, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390300
  • [Presentation] MYCN Amplified Neuroblastoma in Infants : From The Japanese Infantile Neuroblastoma Cooperative Study2008

    • Author(s)
      T Iehara, H Hosoi, et.al.
    • Organizer
      Advances in Neuroblastoma Research 2008
    • Place of Presentation
      Japan Chiba
    • Data Source
      KAKENHI-PROJECT-19591262
  • [Presentation] PD 0332991 Inhibits Cell Proliferation And Induces G1Cell Cycle Arrest against Malignant Rhabdoid Tumor Cells Which Constitutively Express p16Ink4a at a Low Level2008

    • Author(s)
      Katsumi Y, Iehara T, Hajime Hosoi, et.al.
    • Organizer
      40th International Society of Pediatric Oncology
    • Place of Presentation
      Berlin, German
    • Data Source
      KAKENHI-PROJECT-19591262
  • [Presentation] Methylation Analysis of DCR2 gene Using Tumor and Serum DNA of Neuroblastoma Patients2008

    • Author(s)
      Shigeki Yagyu, Tomoko Iehara, Hajime Hosoi, et.al.
    • Organizer
      Advances in Neuroblastoma Research 2008
    • Place of Presentation
      Japan Chiba
    • Data Source
      KAKENHI-PROJECT-19591262
  • [Presentation] 神経芽腫におけるDCR2遺伝子異常メチル化の検出と、予後不良因子、微少残存病変マーカーとしての有用性2007

    • Author(s)
      柳生茂希、細井創, ほか
    • Organizer
      第23回日本小児がん学会学術集会.
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18390300
  • [Presentation] A review of alveolar rhabdomyosarcoma treatment and outcome in Japan, and identification of new drug targets2006

    • Author(s)
      Hosoi H.
    • Organizer
      Educational Lecture. Solid Tumor Program of St. Jude Childrens's Research Hospaital
    • Place of Presentation
      Memphis, TN, USA
    • Year and Date
      2006-12-19
    • Data Source
      KAKENHI-PROJECT-17209055
  • [Presentation] Survival of rhabdomyosarcoma patients in Japan : 1991-2002.Symposium2005

    • Author(s)
      Hosoi H.
    • Organizer
      International Sarcoma Meeting Stuttgart
    • Place of Presentation
      Stuttgart, Germany
    • Year and Date
      2005-06-16
    • Data Source
      KAKENHI-PROJECT-17209055
  • [Presentation] 融合遺伝子陰性横紋筋肉腫におけるHMGA2の機能解析とnetropsinの抗腫瘍効果の検討

    • Author(s)
      大内 一孝, 宮地 充, 桑原 康通, 土屋 邦彦, 家原 知子, 細井 創.
    • Organizer
      第56回日本小児血液・がん学会学術集会,
    • Place of Presentation
      岡山
    • Year and Date
      2014-11-28 – 2014-11-30
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] 血清中筋特異的microRNA miR-206は横紋筋肉腫の新規予後因子となりうる.

    • Author(s)
      宮地 充、土屋邦彦、矢野未央、後藤幸子、坂本謙一、大内一孝、吉田秀樹、桑原康通、今村俊彦、家原知子、細井 創
    • Organizer
      日本癌治療学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-08-28 – 2014-08-30
    • Data Source
      KAKENHI-PROJECT-25461603
  • [Presentation] Is Additional Treatment Necessary for a Residual Tumor in Cases of Intermediate-Risk Neuroblastoma?

    • Author(s)
      T. Iehara, K. Tsuchiya, S. Yagyu, K. Ouchi, Y. Katsumi, Y. Kuwahara, S. Fumino, T. Tajiri, H. Hosoi.
    • Organizer
      Advances in Neuroblastoma Research 2014
    • Place of Presentation
      Cologne, Germany
    • Year and Date
      2014-05-13 – 2014-05-16
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] 小児がん

    • Author(s)
      細井 創
    • Organizer
      第52回日本癌治療学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-08-28 – 2014-08-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] CLINICAL FINDINGS OF ONCOLOGIC EMERGENCY AT DIAGNOSIS.

    • Author(s)
      T. Iehara, K. Tsuchiya , K. Ouchi , M. Miyachi , Y. Kuwahara , S. Fumino , T. Tajiri , H. Hosoi.
    • Organizer
      46th Congressof the International Society of Paediatric Oncology
    • Place of Presentation
      Tronto Cancad.
    • Year and Date
      2014-10-22 – 2014-10-25
    • Data Source
      KAKENHI-PROJECT-26461591
  • [Presentation] Circulating microRNA expression profiles identify patients with metastatic rhabdomyosarcoma.

    • Author(s)
      MiyachiM, Tsuchiya K, Ohuchi K, Yoshida H, Kuwahara Y, Iehara T, Hosoi H.
    • Organizer
      2014 Annual meeting of connective tissue oncology society.
    • Place of Presentation
      ベルリン
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25461603
  • [Presentation] Function analysis of NOXA expression in malignant rhabdoid tumor.

    • Author(s)
      Ouchi K, Kuwahara Y、Tsuchiya K, Iehara T, Hosoi H.
    • Organizer
      第55回日本小児血液・がん学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25461602
  • [Presentation] 閉塞性黄疸で発症した胆道原発横紋筋肉腫の1例

    • Author(s)
      梅田 聡、佐藤真穂、米田光宏、田附裕子 、井上雅美、西川正則、中山雅弘、竹内 真、宮地 充、細井 創、福澤正洋.
    • Organizer
      日本小児血液・がん学会(55)
    • Place of Presentation
      ヒルトン福岡シーホーク(福岡)
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Presentation] RESULTS OF THE JAPAN RHABDOMYOSARCOMA STUDY GROUP JRS-I LRA0401 PROTOCOL, USING VINCRISTINE, DACTINOMYCIN AND CYCLOPHOSPHAMIDE AND RADIATION THERAPY, FOR LOW-RISK EMBRYONAL RHABDOMYOSARCOMA.

    • Author(s)
      H. Hosoi, H. Hojo, H. Okita, J. Hata, H. Masaki, M. Nozaki, T. Soejima, H. Ikeda, K. Horibe, S. Ohta, J. Hara, T. Takimoto, M. Miyachi, K. Tsuchiya, S. Teramukai, Y. Morikawa.
    • Organizer
      46th Congress of the International Society of Paediatric Oncology.
    • Place of Presentation
      Toronto, Canada.
    • Year and Date
      2014-10-22 – 2014-10-25
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] High serum miR-206 expression level predicts poor prognosis in rhabdomyosarcoma.

    • Author(s)
      Miyachi M, Tsuchiya K, Nitta Y, Ohuchi K, Yoshida H, Kuwahara Y, Iehara T, Hosoi H.
    • Organizer
      第56回日本小児血液・がん学会学術集会,
    • Place of Presentation
      岡山
    • Year and Date
      2014-11-28 – 2014-11-30
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] Loss of NOXA expression by INI1/SNF5 loss impaired sensitivity to chemotherapeutic agents in malignant rhabdoid tumor in vitro and vivo

    • Author(s)
      Kazutaka Ouchi, Yasumichi Kuwahara, Tomoko Iehara, Eiichi Konishi, Hajime Hosoi
    • Organizer
      1st International rhabdoid tumor group meeting.
    • Place of Presentation
      Paris, France
    • Year and Date
      2015-04-18 – 2015-04-22
    • Data Source
      KAKENHI-PROJECT-25461602
  • [Presentation] Circulating microRNA expression profiles identify patients with metastatic rhabdomyosarcoma.

    • Author(s)
      MiyachiM, Tsuchiya K, Ohuchi K, Yoshida H, Kuwahara Y, Iehara T, Hosoi H.
    • Organizer
      2014 Annual meeting of connective tissue oncology society.
    • Place of Presentation
      Berlin, Germany.
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] Deciphering the mechanism of PAX3-NCOA2 tumorigenes is in rhabdomyosarcoma.

    • Author(s)
      Yoshida H, Miyachi M, Sakamoto K, Ouchi K , Yagyu S, Kikuchi K, Kuwahara Y, Tsuchiya K , Imamura T,Iehara T, Kakazu N, Hojo H, Hosoi H.
    • Organizer
      2014 Annual meeting of connective tissue oncology society.
    • Place of Presentation
      Berlin, Germany.
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] Is Additional Treatment Necessary for a Residual Tumor in Cases of Intermediate-Risk Neuroblastoma?.

    • Author(s)
      Iehara T,Tsuchiya K,Yagyu S,Ouchi K,Katsumi Y,Kuwahara Y,Fumino S,Tajiri T,Hosoi H.
    • Organizer
      Advances in neuroblastoma research ANR Congress 2014.
    • Place of Presentation
      Cologne, Germany.
    • Year and Date
      2014-05-13 – 2014-05-16
    • Data Source
      KAKENHI-PROJECT-26461591
  • [Presentation] 脂肪芽腫診断におけるPLAG1を用いた細胞遺伝的手法の重要性

    • Author(s)
      吉田 秀樹, 宮地 充, 大内 一孝, 桑原 康通, 土屋 邦彦, 家原 知子, 小西 英一, 柳澤 昭夫, 細井 創
    • Organizer
      第56回日本小児血液・がん学会学術集会,
    • Place of Presentation
      岡山
    • Year and Date
      2014-11-28 – 2014-11-30
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] 忘れられたがんに光を~成人期に発症した「小児がん」~

    • Author(s)
      細井 創
    • Organizer
      第7回福島小児腫瘍研究会
    • Place of Presentation
      福島
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] High serum miR-206 expression levels define an aggressive rhabdomyosarcoma subtype

    • Author(s)
      Miyachi M, Tsuchiya K, Yagyu S, Iehara T, Hosoi H
    • Organizer
      第71回日本癌学会学術集会
    • Place of Presentation
      札幌教育文化会館(北海道)
    • Data Source
      KAKENHI-PROJECT-21249085
  • [Presentation] レチノイン酸関連遺伝子発現比による神経芽腫患者予後予測

    • Author(s)
      辻 桂嗣, 家原 知子, 柳生 茂希, 勝見 良樹, 田村 真一, 杉本 徹, 細井 創.
    • Organizer
      第56回日本小児血液・がん学会学術集会,
    • Place of Presentation
      岡山
    • Year and Date
      2014-11-28 – 2014-11-30
    • Data Source
      KAKENHI-PROJECT-25253095
  • [Presentation] The Japan Rhabdomyosarcoma Study Group(JRSG):Preliminary Results from the JRS-1 Study and Background for the Next JRS-2 Treatment Protocols.

    • Author(s)
      Hosoi H.
    • Organizer
      International Society of Pediatric Oncology 8th SIOP Asia Congress SEOUL.
    • Place of Presentation
      Seoul,Korea
    • Year and Date
      2014-04-17 – 2014-04-18
    • Data Source
      KAKENHI-PROJECT-25253095
  • 1.  IEHARA Tomoko (20285266)
    # of Collaborated Projects: 20 results
    # of Collaborated Products: 99 results
  • 2.  MIYACHI Mitsuru (40584983)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 43 results
  • 3.  Kikuchi Ken (40453104)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 18 results
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    # of Collaborated Products: 54 results
  • 5.  柳生 茂希 (10572547)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 23 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 6 results
  • 12.  KUBOTA Tetsurou (00118944)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  IKEDA Hitoshi (10326928)
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Products: 5 results
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    # of Collaborated Products: 3 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Products: 1 results
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  • 46.  MASAKI Eiichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  NOGAMI Keiji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  SAKAI Kohei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  嘉数 直樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  林 富
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  嶋 緑倫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 52.  石原 卓
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 53.  小林 幸夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 54.  野本 順子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 55.  酒井 敏行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 56.  市川 美紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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