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OKAMURA Kunihiro  岡村 州博

ORCIDConnect your ORCID iD *help
… Alternative Names

岡村 州彦  オカムラ クニヒロ

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Researcher Number 90124560
External Links
Affiliation (based on the past Project Information) *help 2009 – 2011: Tohoku University, 大学院・医学系研究科, 名誉教授
2010: 東北大学, 医学系研究科, 名誉教授
2009 – 2010: 東北大学, 大学院医学系研究科, 名誉教授
2007 – 2008: Tohoku University, 大学院・医学系研究科, 教授
2006: 東北大学, 大学院医学系研究科, 教授 … More
2005: Tohoku University, Graduate School of Medicine, Professor, 大学病院医学系研究科, 教授
1999 – 2005: Graduate School of Medicine, Tohoku University, Professor, 大学院・医学系研究科, 教授
1997 – 1998: 東北大学, 医学部, 助教授
1994 – 1995: 東北大学, 医学部, 講師
1994: Tohoku University School of Medicine, Department of Obstetrics and Gynecology, associate Professor, 医学部, 助教授
1993: 東北大学, 医学部・附属病院, 講師
1990 – 1991: 東北大学, 医学部附属病院, 講師
1990: 東北大学, 医病産婦人科, 講師
1989: 東北大学, 医学部・附属病院, 講師 Less
Review Section/Research Field
Principal Investigator
Embryonic/Neonatal medicine / Obstetrics and gynecology / Embryonic/Neonatal medicine / Obstetrics and gynecology
Except Principal Investigator
Embryonic/Neonatal medicine / 小児外科 / Virology / Embryonic/Neonatal medicine / Obstetrics and gynecology / Public health/Health science
Keywords
Principal Investigator
胎児心拍変動 / gamma distribution / Time-frequency analysis / パワースペクトル解析 / 胎児心拍数変動 / ウェーブレット変換 / 時間周波数解析 / スペクトル分析 / 胎児 / スペクトル解析 … More / ECoG spikes / fetal electrocorticogram / myography / rapid maturation of placental vascular function / environmental stress during early pregnancy / fetal circulatory failure / 羊胎仔実験 / 心筋壁内膜側・外膜側 / 位相差トラッキング法 / 胎児心筋厚み変化速度 / 胎児胎盤末梢血管系 / 羊胎仔胎児胎盤循環栓 / Myograph / 胎児胎盤末梢循環系 / スパイク波形 / 胎児皮質脳波 / マイオグラフ / 早期成熟モデル / 子宮内ストレス / 羊胎仔胎児胎盤循環不全 / complexity / Fetal heart rate / フラクタル構造 / ガンマ分布 / 複雑系 / fetus / beat-to-beat interval / spectral analysis / biorhythm / サーカディアンリズム / 心拍変動 / 生体リズム / fetal acidemia / fetal heart beat fluctuation / wavelet transform / 胎児心拍 / fluctuation / fetal heart rate / Fetus / power spectral analysis / 胎児仮死 / エストロゲン / 光環境 / 子宮内膜症 / 人工赤血球 / 胎児低酸素症 / 妊娠高血圧症候群 / 11 β hydroxydehydrogenase 2 / DNA methylation / Wired myography / Oligodendrocyte progenitor / Stem cell theory / Fetal programming / Cckbr / バイサルファイト法 / H3, H4 Histone / epigenetics / H3,H4 Histone / Igf2 promoter P1領域 / 網羅的研究 / うつ病 / 低栄養妊娠マウスモデル / オリゴデンドロサイト / 生活習慣病 / Fetal origin of adult disease / 甲状腺ホルモン / 胎盤 / OATP-E / 有機アニオントランスポーター / 羊胎仔胎児仮死慢性実験モデル / 心臓弁運動解析 / ウェーブレット解析 / 胎仔心不全 / 脳室周囲白質軟化症 / 周波数解析 / 超音波ドプラ信号 … More
Except Principal Investigator
ELISA / High frequency area / Fetal distress / Power spectrum / 胎児生理学 / スペクトル解析 / ドプラ / 低酸素血症 / パワースペクトル成分 / 胎児心拍数 / 羊実験モデル / HF領域 / LF領域 / 胎児仮死 / パワースペクトル / Fetal Endoscopy / Fetal Lamb / Biliary Atresia / Fetal Surgery / 胎仔内視鏡 / 羊胎仔 / 胆道閉鎖症 / 胎仔外科手術 / immunofluorescence staining / polymerase chain reaction / Western blot / human parvovirus / アビジン・ビオチン / 蛍光抗体法 / ELISA法 / PCR / VPー1 / B19 / ヒトパルボウイルス / 血清診断 / 関節リウマチ / 非免疫性胎児水腫 / パルボウイルス / 免疫蛍光染色法 / 核酸重合反応法 / ウエスタンブロット法 / 免疫酵素法 / ヒト・パルボウイルス / 環境センサー遺伝子 / 胎児発育 / 子宮環境 / 血管新生 / 胎盤形成 / エストラジオール / 妊娠 / 血管内皮前駆細胞 / Igf axis / 胎児発育不全 / ビタミン補充 / ヒストン修飾 / エピジェネティック / 葉酸欠乏食 / 低蛋白食 / 胎児プログラミング / 生活習慣病発症 / 家庭血圧 / 遺伝 / 胎児発育遅延 / 24時間自由行動下血圧 / 高血圧症 / 妊娠高血圧 / Barker仮説 Less
  • Research Projects

    (17 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (24 People)
  •  Nanomicro-therapy for pregnancy-induced hypertensionPrincipal Investigator

    • Principal Investigator
      OKAMURA Kunihiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Tohoku University
  •  環境センサー遺伝子を用いた胎児発育を促進する子宮環境メカニズムの解明

    • Principal Investigator
      OHTA Hidenobu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      独立行政法人国立精神・神経医療研究センター
      Tohoku University
  •  The lighting effects on development of endometrial hyperplasiaPrincipal Investigator

    • Principal Investigator
      OKAMURA Kunihiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Tohoku University
  •  The analysis of maternal endothelial function in the deteriorated intrauterine condition and the possibility of repairing the fetal status

    • Principal Investigator
      CHISAKA Hiroshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  The study on incidence of lifestyle-related disease associated with environmental and genetic factors during intrauterine, neonatal, and the youth period

    • Principal Investigator
      IMAI Yutaka
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Public health/Health science
    • Research Institution
      Tohoku University
  •  Experimental study for the programming of fetal brain by food retraction in pregnancy and its resettingPrincipal Investigator

    • Principal Investigator
      OKAMURA Kunihiro
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  The experimental study of the effects of sequential fetal acidemia on the susceptibility of circulatory failure in adulthood.Principal Investigator

    • Principal Investigator
      OKAMURA Kunihiro
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  胎盤絨毛細胞へのアニオントランスポーター遺伝子導入による胎児治療の試みPrincipal Investigator

    • Principal Investigator
      岡村 州博
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Tohoku University
  •  超音波ドップラー信号のウェーブレット解析による胎児心不全の診断法の開発への試みPrincipal Investigator

    • Principal Investigator
      岡村 州博
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Tohoku University
  •  The analysis of thefetal heart rate fluctuation as a date from complexity system and a design of fetal m onitoring system based on itPrincipal Investigator

    • Principal Investigator
      OKAMURA Kunuhiro
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Tohoku university
  •  A study of biorhythm using a power spectral analysis on the fluctuation in fetal and maternal beat-to-beat intervalsPrincipal Investigator

    • Principal Investigator
      OKAMURA Kunihiro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      TOHOKU UNIVERSITY
  •  A design of fetal monitoring system based on the time-frequency analysis of fetal heart beat fluctuation using wavelet transformPrincipal Investigator

    • Principal Investigator
      OKAMURA Kunihiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Tohoku University
  •  The study of the fetal heart rates changes in hypoxemia by spectral analysis

    • Principal Investigator
      KIMURA Yoshitaka, 渡辺 孝紀
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      TOHOKU UNIVERSITY
  •  胎児外科手技を用いた胆道閉鎖症モデル(肝外胆管および肝)作成による病態解明の試み

    • Principal Investigator
      OHI Ryoji
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      小児外科
    • Research Institution
      Tohoku University
  •  Analysis of fetal autonomic nerve activity by a power spectrum of heart beat-to-beat intervals and its application for clinical fetal monitoringPrincipal Investigator

    • Principal Investigator
      OKAMURA Kunihiro
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  A study of systemic blood flow in the fetus with cardiac failure using a sheep fetus modelPrincipal Investigator

    • Principal Investigator
      OKAMURA Kunihiro
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku Univerisity
  •  Development of diagnostic methods for human parvovirus infection

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Virology
    • Research Institution
      Tohoku Univeristy

All 2010 2009 2008 2007

All Journal Article Presentation

  • [Journal Article] The uterus sustains stable biological clock during pregnancy2010

    • Author(s)
      Akiyama S, Ohta H, Watanabe S, Moriya T, Hariu A, Nakahata N, Chisaka H, Matsuda T, Kimura Y, Tsuchiya S, Tei H, Okamura K, Yaegashi N
    • Journal Title

      Tohoku Journal of Experimental Medicine

      Volume: 221 Pages: 287-298

    • NAID

      10027085356

    • URL

      http://dx.doi.org/10.1620/tjem.221.287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591408
  • [Journal Article] Maternal feeding controls fetal biological clock2008

    • Author(s)
      Ohta H, Okamura K.
    • Journal Title

      PLoS ONE 2 ; 3(7)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390443
  • [Journal Article] The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA.2007

    • Author(s)
      Jafar S, K Okamura
    • Journal Title

      Nature 450

      Pages: 908-912

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390443
  • [Journal Article] Serum levels of SDF-1 throughout normal pregnancy and patients with preeclampsia2007

    • Author(s)
      Okamura K
    • Journal Title

      Journal of Society for Gynecologic Investigation 13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591889
  • [Journal Article] Food Restriction in pregnant mice can induced changes in Histone Modifications and suppress gene expression in fetus2007

    • Author(s)
      Jafar S, M Nakamura, T Ito, Y Kimura, K Okamura
    • Journal Title

      Nucleic Acids Symposium Series Oxford University Press No.51

      Pages: 125-126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390443
  • [Journal Article] The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA2007

    • Author(s)
      Jafar S, K Okamura.
    • Journal Title

      Nature 4507

      Pages: 908-912

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390443
  • [Presentation] 母体葉酸欠乏が及ぼす胎仔胎盤発育における影響とそのエピジェネティックス制御機構解析2009

    • Author(s)
      松田尚美、千坂泰、木村芳孝、八重樫伸生、岡村州博
    • Organizer
      第61回日本産科婦人科学会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2009-04-05
    • Data Source
      KAKENHI-PROJECT-18390443
  • [Presentation] 母体葉酸欠乏が及ぼす胎盤発育およびIgf-axisの発現制御のエピジェネティックス基盤解析2008

    • Author(s)
      松田尚美、千坂泰、木村芳孝、Jafar Sharif、岡村州博
    • Organizer
      第16回日本胎盤学会
    • Place of Presentation
      浜松市
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-18390443
  • [Presentation] 母体葉酸欠乏が及ぼす胎盤発育およびIgf-axisの発現制御のエピジェネテイックス基盤解析2008

    • Author(s)
      松田尚美、千坂泰、木村芳孝、Jafar Sharif、岡村州博
    • Organizer
      第16回日本胎盤学会
    • Place of Presentation
      浜松市
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-18390443
  • [Presentation] Transcriptional suppression of Igf2 mediated by altered histone modifications in a maternal protein restricted IUGR mousemodel2007

    • Author(s)
      Nakamura M, J Sharif, T ITO, H Chisaka, Y Kimura, K Okamura
    • Organizer
      34 Annual Meeting of Fetal and Neonatal Physiological Society
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2007-08-29
    • Data Source
      KAKENHI-PROJECT-18390443
  • [Presentation] Maternal Low protein Diet Aggravates Fetal White Matter Damage Caused by Infection.2007

    • Author(s)
      Ito T, K Uchida, M Nakamura, _H Chisaka, Kimura Y, K Okamura.
    • Organizer
      34 Annual Meeting of Fetal and Neonatal Physiological Society
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2007-08-29
    • Data Source
      KAKENHI-PROJECT-18390443
  • [Presentation] Transcriptional suppression of Igf2 mediated by altered histone modifications in a maternal protein restricted IUGR mouse model2007

    • Author(s)
      Nakamura M, J Sharif, T Ito, H Chisaka, Kimura Y, K Okamura.
    • Organizer
      34 Annual Meeting of Fetal and Neonatal Physiological Society.
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2007-08-27
    • Data Source
      KAKENHI-PROJECT-18390443
  • [Presentation] Maternal Low protein Diet Aggravates Fetal White Matter Damage Caused by Infection2007

    • Author(s)
      Ito T, K Uchida, M Nakamura, H Chisaka, Y Kimura, K Okamura
    • Organizer
      4 Annual Meeting of Fetal and Neonatal Physiological Society
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2007-08-29
    • Data Source
      KAKENHI-PROJECT-18390443
  • 1.  KIMURA Yoshitaka (40261622)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 8 results
  • 2.  CHISAKA Hiroshi (40323026)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 8 results
  • 3.  SUGAWARA Junichi (60280880)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  OHTA Hidenobu (80422103)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 5.  MUROTSUKI Jun (50239555)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KOBAYASHI Kouju (30250781)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  OHKUBO Takayoshi (60344652)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  渡辺 孝紀 (70221687)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  OHWADA Kazunori
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  IMAI Yutaka (40133946)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KATO Hidemasa (50292123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  OKAMOTO Satoshi (40420020)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  SUGAMURA Kazuo (20117360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SASAKI Takeshi (50110656)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NAKAMURA Masataka (30180392)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  OHI Ryoji (50004734)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YAMAKI Kuniji (70091759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  CHIBA Toshio (20171944)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  HAYASHI Yutaka (40125638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  阿部 高明 (80292209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  谷川原 真吾 (90207176)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  遠藤 尚文 (00213596)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  安井 友春 (30302087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  SHIRAISHI Hiroyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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