Aramaki Yukihiko 新槇幸彦

… Alternative Names

ARAMAKI Yukihiko 新槇幸彦

新槙幸彦アラマキユキヒコ

新槇幸彦アラマキユキヒコ

新〓幸彦アラマキユキヒコ

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Researcher Number	90138959
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2018: 東京薬科大学, 薬学部, 教授 2006 – 2013: 東京薬科大学, 薬学部, 教授 2001 – 2003: 東京薬科大学, 薬学部, 助教授 1993 – 1996: 東京薬科大学, 薬学部, 助教授
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / Medical pharmacy / 医薬分子機能学 Except Principal Investigator Medical systems / Gastroenterology
Keywords	Principal Investigator リポソーム / alpha2-macroglobulin / macrophage / liposome / α_2-マクログロブリン / マクロファージ / 粘膜ワクチン / アジュバント / CpG-ODN / 薬学 … More / HPV / ヒトパピローマウイルス / 子宮頸がん / がんワクチン / tyrosine kinase / mannose receptor / B cell / グリコシダーゼ / B-細胞 / α2-マクログロブリン / Fcレセプター / チロシンキナーゼ / マンノースレセプター / B細胞 / Fc-receptor / alpha_2-マクログロブリン / α_2マクログロブリン / Fc-レセプター / アジュバンド / ナノキャリアー / IL-6 / IgA / IL-12 / 粘膜免疫 / IgE / CpG・ODN / サイトカイン / 経皮投与 / 免疫応答 / アトピー性皮膚炎 / Th2バランス / Th1 … More Except Principal Investigator 超音波 / 遺伝子導入 / リポソーム / 超音波照射 / Asiologlycoprotein receptor / ultrasound / Gene transfer / 遺伝子遺入 / アシアロ糖タンパク受容体 / アンチセンス / ジストロフィン / 筋ジストロフィー / バブルリポソーム / 遺伝子細胞療法 / ペプチド修飾リポソーム / 遺伝子治療 / 超音波造影ガス封入リポソーム / 新生血管 / リボソーム / 遺伝子道入 / 血管再生 / 超音波造影 Less

Development of a nasal therapeutic vaccine to cervical cancer using liposomesPrincipal Investigator
- Principal Investigator
  
  Aramaki Yukihiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Therapeutic systems of muscular dystrophy by morpholino oligonucleotide-loaded nanobubble and ultrasound
- Principal Investigator
  
  NEGISHI yoichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Tokyo University of Pharmacy and Life Science
IL-6 acts as a key cytokine in the augmentation of mucosal immunity following intranasal administration of antigen with liposomesPrincipal Investigator
- Principal Investigator
  
  ARAMAKI Yukihiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Gene transfer system into mesenchymal stem cell by peptide-modified liposomes and ultrasound technology
- Principal Investigator
  
  NEGISHI Yoichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical systems
- Research Institution
  Tokyo University of Pharmacy and Life Science
Low invasive therapeutic system for vascular diseases by neovascular specific liposomes containing US-contrast gas
- Principal Investigator
  
  NEGISHI Yoichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Tokyo University of Pharmacy and Life Science
Application of CpG-ODN for nasal vaccine developmentPrincipal Investigator
- Principal Investigator
  
  ARAMAKI Yukihiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
新規な超音波造影ガス封入リポソームによる非侵襲的虚血性血管再生療法のシステム開発
- Principal Investigator
  
  NEGISHI Youichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical systems
- Research Institution
  Tokyo University of Pharmacy and Life Science
オリゴヌクレオチドによる免疫応答の改変に関する研究Principal Investigator
- Principal Investigator
  
  新槇幸彦 (新槙幸彦)
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  医薬分子機能学
- Research Institution
  Tokyo University of Pharmacy and Life Science
Ultrasound enhances gene expression of asialoglycoprotein receptor medieted gene transfer into hepatic cells
- Principal Investigator
  
  MORITASU Fuminori
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical University
Activation Mechanism of Macrophages by LiposomesPrincipal Investigator
- Principal Investigator
  
  ARAMAKI Yukihiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Elucidation of the Mechanism for Macrophage Activation induced by LiposomesPrincipal Investigator
- Principal Investigator
  
  ARAMAKI Yukihiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science, School of Pharmacy

All 2018 2017 2016 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent Other

[Journal Article] Nasal vaccination with pneumococcal surface protein A in combination with cationic liposomes consisting of DOTAP and DC-chol confers antigen-mediated protective immunity against Streptococcus pneumoniae infections in mice2018
- Author(s)
  Tada Rui、Suzuki Hidehiko、Takahashi Saeko、Negishi Yoichi、Kiyono Hiroshi、Kunisawa Jun、Aramaki Yukihiko
- Journal Title
  
  International Immunopharmacology
  
  Volume: 61 Pages: 385-393
- DOI
  10.1016/j.intimp.2018.06.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08415, KAKENHI-PROJECT-18K06798
[Journal Article] Intranasal administration of cationic liposomes enhanced granulocyte?macrophage colony-stimulating factor expression and this expression is dispensable for mucosal adjuvant activity2018
- Author(s)
  Tada Rui、Hidaka Akira、Kiyono Hiroshi、Kunisawa Jun、Aramaki Yukihiko
- Journal Title
  
  BMC Research Notes
  
  Volume: 11 Issue: 1 Pages: 472-472
- DOI
  10.1186/s13104-018-3591-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08415, KAKENHI-PROJECT-18K06798
[Journal Article] Polymeric Caffeic Acid Is a Safer Mucosal Adjuvant That Augments Antigen-Specific Mucosal and Systemic Immune Responses in Mice2018
- Author(s)
  Tada Rui、Yamanaka Daisuke、Ogasawara Miki、Saito Momoko、Ohno Naohito、Kiyono Hiroshi、Kunisawa Jun、Aramaki Yukihiko
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 15 Issue: 9 Pages: 4226-4234
- DOI
  10.1021/acs.molpharmaceut.8b00648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08415, KAKENHI-PROJECT-18K06798, KAKENHI-PROJECT-18H05280
[Journal Article] Mechanisms of Enhanced Antigen Delivery to Murine Dendritic Cells by the Cationic Liposomes2017
- Author(s)
  Takahashi Saeko、Tada Rui、Negishi Yoichi、Aramaki Yukihiko
- Journal Title
  
  Open Journal of Immunology
  
  Volume: 07 Issue: 04 Pages: 85-101
- DOI
  10.4236/oji.2017.74007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08415, KAKENHI-PROJECT-15K18935
[Journal Article] Attachment of class B CpG ODN onto DOTAP/DC-chol liposome in nasal vaccine formulations augments antigen-specific immune responses in mice2017
- Author(s)
  Rui Tada, Shoko Muto, Tomoko Iwata, Akira Hidaka, Hiroshi Kiyono, Jun Kunisawa, Yukihiko Aramaki
- Journal Title
  
  BMC Research Notes
  
  Volume: 10 Issue: 1 Pages: 68-68
- DOI
  10.1186/s13104-017-2380-8
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08415, KAKENHI-PROJECT-15K18935
[Journal Article] The Development of an Ultrasound-mediated Nucleic Acid Delivery System for Treating Muscular Dystrophies2012
- Author(s)
  Negishi Y, Hamano N, Shiono H, Akiyama S, Endo-Takahashi Y, Suzuki R, Maruyama K, Aramaki Y
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 132 Issue: 12 Pages: 1383-1388
- DOI
  10.1248/yakushi.12-00235-2
- NAID
  130002489535
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2012-12-01
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-23300193
[Journal Article] Delivery of an angiogenic gene into ischemic muscle by novel bubble liposomes followed by ultrasound exposure.2011
- Author(s)
  Y.Negishi, K.Matsuo, Y.Endo-Takahashi, K.Suzuki, Y.Matsuki, N.Takagi, R.Suzuki, K.Maruyama, Y.Aramaki
- Journal Title
  
  Pharm.Res.
  
  Volume: 28 Pages: 712-719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Delivery of an Angiogenic Gene into Ischemic Muscle by Novel Bubble Liposomes Followed by Ultrasound Exposure.2011
- Author(s)
  Negishi Y, Matsuo K, Endo-Takahashi Y, Suzuki K, Matsuki Y, Takagi N, Suzuki R, Maruyama K, Aramaki Y
- Journal Title
  
  Pharm.Res. 28
  
  Pages: 712-719
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Development of gene delivery system into skeletal muscles by bubble liposomes and ultrasound.2010
- Author(s)
  Y.Negishi, Y.Endo-Takahashi, R.Suzuki, K.Maruyama, Y.Aramaki
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 130 Pages: 1489-1496
- NAID
  130000451700
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Intravenous Delivery of pDNA and siRNA into Muscle with Bubble Liposomes and Ultrasound2010
- Author(s)
  Y.Negishi, S.Sekine, Y.Endo, N.Nishijima, R.Suzuki, K.Maruyama, Y.Aramaki
- Journal Title
  
  9^<th> International Symposium Therapeutic Ultrasound. AIP conference proceedings 1215
  
  Pages: 299-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Development of gene delivery system into skeletal muscles by bubble liposomes and ultrasound.2010
- Author(s)
  Negishi Y, Endo-Takahashi Y, Suzuki R, Maruyama K, Aramaki Y
- Journal Title
  
  YAKUGAKU ZASSHI 130
  
  Pages: 1489-1496
- NAID
  130000451700
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Enhanced laminin-derived peptide AG73-mediated liposomal gene transfer by bubble liposomes and ultrasound.2010
- Author(s)
  Y.Negishi, D.Omata, H.lijima, Y.Takabayashi, K.Suzuki, Y.Endo, R.Suzuki, Maruyama, M.Nomizu, Y.Aramaki
- Journal Title
  
  Mol.Pharm. 7
  
  Pages: 217-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Enhanced laminin-derived peptide AG73-mediated liposomal gene transfer by bubble liposomes and ultrasound.2010
- Author(s)
  Negishi Y, Omata D, Iijima H, Takabayashi Y, Suzuki K, Endo Y, Suzuki R, Maruyama K, Nomizu M, Aramaki Y
- Journal Title
  
  Mol Pharm. 7
  
  Pages: 217-226
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Preparation and characterization of laminin-derived peptide AG73-coated liposomes as a selective gene delivery tool.2010
- Author(s)
  Negishi Y, Omata D, Iijima H, Hamano N, Endo-Takahashi Y, Nomizu M, Aramaki Y
- Journal Title
  
  Biol Pharm Bull. 33
  
  Pages: 1766-1769
- NAID
  130000402377
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Ultrasound Imaging and Gene Delivery by AG73-modified Bubble Liposomes2009
- Author(s)
  Y. Negishi, Y. Tsunoda, N. Hamano, Y. Endo, N. Takagi, R. Suzuki, K, Maruyama, C. Batsuren, M. Emoto, M. Nomizu, Y. Aramaki
- Journal Title
  
  Peptide Science 2008
  
  Pages: 127-130
- NAID
  10027166068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Ultrasound imaging and gene delivery by AG73-modified bubble liposomes2009
- Author(s)
  Negishi Y, Tsunoda Y, Endo Y, Takagi N, Suzuki R, Maruyama K, Emoto M, Nomizu M, Aramaki A
- Journal Title
  
  Peptide Science 2008
  
  Pages: 127-130
- NAID
  10027166068
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Intravenous Delivery of pDNA and siRNA into Muscle with Bubble Liposomes and Ultrasound2009
- Author(s)
  Negishi Y, Sekine S, Endo Y, Nishijima N, Suzuki R, Maruyama K, Aramaki Y
- Journal Title
  
  9th International Symposium Therapeutic Ultrasound. AIP Conf.Proc. 1215
  
  Pages: 299-302
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] AG73-mediated Liposomal Gene Transfection Accelerated by Bubble Liposomes and Ultrasound2009
- Author(s)
  D. Omata, Y. Negishi, Y. Endo, R. Suzuki, K. Suzuki, K. Maruyama, M. Nomizu, Y. Aramaki
- Journal Title
  
  Peptide Science 2008
  
  Pages: 73-76
- NAID
  10027165974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300179
[Journal Article] Intramuscular Injection of Angiogenic Gene with Bubble Liposomes Followed by Ultrasound Exposure to Improve Angiogenesis
- Author(s)
  Negishi Y, Endo-Takahashi Y, Takagi N, Suzuki R, Maruyama K, Aramaki Y
- Journal Title
  
  10th International Symposium Therapeutic Ultrasound. AIP Conf.Proc. (in press)
- Data Source
  KAKENHI-PROJECT-20300179
[Patent] モルフォリノ搭載バブルリポソームを有効成分としてなる筋ジストロフィー治療薬2012
- Inventor(s)
  根岸洋一, 高橋葉子, 丸山一雄, 新槇幸彦
- Industrial Property Rights Holder
  学校法人東京薬科大学, ネッパジーン株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2012-04-25
- Overseas
- Data Source
  KAKENHI-PROJECT-23300193
[Patent] モルフォリノ搭載バブルリポソームを有効成分としてなる筋ジストロフィー治療薬2011
- Inventor(s)
  根岸洋一, 高橋葉子, 丸山一雄, 新槇幸彦
- Industrial Property Rights Holder
  学校法人東京薬科大学, ネッパジーン株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2011-098182
- Filing Date
  2011-04-26
- Data Source
  KAKENHI-PROJECT-23300193
[Patent] モルフォリノ搭載バブルリポソームを有効成分としてなる筋ジストロフィー治療薬2011
- Inventor(s)
  根岸洋一、高橋葉子、丸山一雄、新槇幸彦
- Industrial Property Rights Holder
  学校法人東京薬科大学、ネッパジーン株式会社
- Industrial Property Number
  2011-098182
- Filing Date
  2011-04-26
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 傷害関連分子パターンの正電荷リポソームの有する粘膜アジュバント活性に対する関与2018
- Author(s)
  滝瑠瑛、多田塁、大島亮洋、棚澤佑哉、近江珠怜、根岸洋一、清野宏、國澤純、新槇幸彦
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-16K08415
[Presentation] 酵素重合化カフェ酸を利用した新規粘膜ワクチンシステムの開発2018
- Author(s)
  永井柚帆、多田塁、小笠原樹、齊藤桃子、山中大輔、櫻井康博、根岸洋一、國澤純、大野尚仁、新槇幸彦
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-16K08415
[Presentation] IL-6 acts as a key cytokine in the enhancement of mucosal immunity following intranasal administration of antigen with cationic liposomes2016
- Author(s)
  Yukihiko Aramaki, Rui Tada, Emi Honjo, Naoko Iwase, Hiroshi Kiyono, Jun Kunisawa
- Organizer
  Virus-Like Particle & Nano-Particle Vaccines VLPNPV 2016
- Place of Presentation
  Leiden, The Netherlands
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08415
[Presentation] バブルリポソームと超音波照射併用した修飾型モルフォリノオリゴ導入による筋ジストロフィー治療システムの開発2014
- Author(s)
  間山彩, 根岸洋一, 秋山早希, 櫻井あかね, 高橋葉子, 片桐文彦, 野水基義, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと高密度焦点式超音波(HIFU)による骨格筋への局限的遺伝子デリバリー2013
- Author(s)
  奥津　大輔、根岸　洋一、濱野　展人、小俣　大樹、髙橋　葉子、鈴木　亮、丸山　一雄、新槇　幸彦
- Organizer
  第29回日本DDS学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと高密度焦点式超音波による核酸導入法の確立2013
- Author(s)
  山根正也, 根岸洋一, 奥津大輔, 濱野展人, 小俣大樹, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第13回遺伝子・デリバリー研究会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2013-05-11
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] アニオン性脂質含有バブルリポソームの開発2013
- Author(s)
  根岸洋一, 菊池太希, 高橋葉子, 小栗由貴子, 杉本勝俊, 森安史典, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第12回日本超音波治療研究会
- Place of Presentation
  東京
- Year and Date
  2013-11-30
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと超音波を利用した心臓への核酸デリバリーシステムの有用性評価2013
- Author(s)
  根岸洋一, 秋山早希, 山根正也, 間山彩, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第29回日本DDS学会
- Place of Presentation
  京都
- Year and Date
  2013-07-04
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 筋ジストロフィーモデルマウス心筋へのバブルリポソーム併用超音波核酸デリバリーと組織内分布2013
- Author(s)
  秋山早希, 根岸洋一, 間山彩, 山根正也, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第29回日本DDS学会
- Place of Presentation
  京都
- Year and Date
  2013-07-04
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 筋ジストロフィー疾患治療のための超音波併用バブルリポソームによるアンチセンスデリバリーシステムの構築2013
- Author(s)
  間山彩, 根岸洋一, 秋山早希, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第13回遺伝子・デリバリー研究会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2013-05-11
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 核移行シグナルペプチド内封AG73修飾リポソームによる新規遺伝子デリバリーツールの開発2012
- Author(s)
  根井　彰浩、根岸　洋一、高橋　佐慧子、小俣　大樹、鈴木　亮、丸山　一雄、野水　基義、新槇　幸彦
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2012
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22650119
[Presentation] 筋ジストロフィー治療に向けた超音波核酸デリバリーシステムの開発2012
- Author(s)
  濱野展人, 根岸洋一, 塩野瞳, 秋山早希, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  日本薬学会第132年会
- Place of Presentation
  大阪
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと超音波照射併用による心臓への核酸デリバリー2012
- Author(s)
  根岸洋一, 塩野瞳, 秋山早希, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第12回遺伝子・デリバリー研究会夏季セミナー
- Place of Presentation
  北九州
- Year and Date
  2012-07-30
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと超音波照射併用による心筋への核酸デリバリー2012
- Author(s)
  根岸洋一, 塩野瞳, 秋山早希, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2012
- Place of Presentation
  仙台
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 超音波応答性バブルリポソームの核酸・遺伝子デリバリーシステムへの応用展開2012
- Author(s)
  根岸洋一、高橋葉子、鈴木亮、丸山一雄、新槇幸彦
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2011
- Place of Presentation
  大阪大学コンベンションセンター、大阪(招待講演)
- Year and Date
  2012-09-01
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 核移行シグナルペプチド内封AG73修飾リポソームによる新規遺伝子デリバリーツールの開発2012
- Author(s)
  根井彰浩,根岸洋一,高橋佐慧子,小俣大樹,鈴木亮,丸山一雄,野水基義,新槇幸彦
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2012
- Year and Date
  2012-09-25
- Data Source
  KAKENHI-PROJECT-22650119
[Presentation] 筋ジストロフィー治療に向けた超音波核酸デリバリーシステムの開発2012
- Author(s)
  濱野展人、根岸洋一、塩野瞳、秋山早希、高橋葉子、鈴木亮、丸山一雄、新槇幸彦
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学、札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] バブルリポソームと超音波照射併用による心臓への核酸デリバリー2012
- Author(s)
  根岸洋一,　塩野瞳,　秋山早希, 髙橋葉子,　鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第12回遺伝子・デリバリー研究会　夏季セミナー
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] PMO delivery system with Bubble liposomes and ultrasound exposure into skeletal muscles of the mdx mice2011
- Author(s)
  Y.Negishi, Y.Ishii, S.Sekine, Y.Endo-Takahashi, R.Suzuki, K.Maruyama, Y.Aramaki
- Organizer
  American Society of Gene & Cell Therapy 14th Annual Meeting
- Place of Presentation
  Washington State Convention & Trade Center, Seattle, USA
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] PMO delivery system with Bubble liposomes and ultrasound exposure into skeletal muscles of the mdx mice2011
- Author(s)
  Negishi Y, Ishii Y, Sekine S, Endo-Takahashi Y, Suzuki R, Maruyama K, Aramaki Y
- Organizer
  American Society of Gene & Cell Therapy 14th Annual Meeting
- Place of Presentation
  Seattle
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] DOTAP含有バブルリポソームによる全身循環を介した下肢虚血部位への超音波遺伝子導入法の検討2011
- Author(s)
  松木勇樹, 根岸洋一, 高橋葉子, 加藤妥治, 高山華奈, 高木教夫, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] バブルリポソーム併用超音波遺伝子導入法を用いた間葉系幹細胞への遺伝子導入効果の解析2011
- Author(s)
  鈴木健太郎, 根岸洋一, 高橋葉子, 高橋良太, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  日本薬学会第131 年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22650119
[Presentation] バブルリポソーム併用超音波遺伝子導入法を用いた間葉系幹細胞への遺伝子導入効果の解析2011
- Author(s)
  鈴木健太郎, 根岸洋一, 高橋葉子, 高橋良太, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22650119
[Presentation] バブルリポソーム併用超音波遺伝子デリバリーシステムの疾患治療への応用2011
- Author(s)
  根岸洋一,高橋葉子,高木教夫,鈴木亮,丸山一雄,新槇幸彦
- Organizer
  第3回超音波とマイクロバブルの相互作用に関するシンポジウム
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] バブルリポソーム併用超音波遺伝子デリバリーシステムの疾患治療への応用2011
- Author(s)
  根岸洋一, 高橋葉子, 高木教夫, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  第3回超音波とマイクロバブルの相互作用に関するシンポジウム
- Place of Presentation
  横浜
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] 超音波応答性バブルリポソームの核酸・遺伝子デリバリーシステムへの応用展開2011
- Author(s)
  根岸洋一, 高橋葉子, 鈴木亮, 丸山一雄, 新槇幸彦
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2011
- Place of Presentation
  大阪
- Year and Date
  2011-09-02
- Invited
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] IL-6 acts as a key cytokine in the augmentation of mucosal immunity following intranasal administration of antigen with CpG-ODN and hliosomes2010
- Author(s)
  新槇幸彦
- Organizer
  The Third International Conference on Modern Vaccines/Adjuvants Formulation 2010
- Place of Presentation
  カンヌ,フランス
- Data Source
  KAKENHI-PROJECT-22590073
[Presentation] bFGF Gene Transfer into Skeletal Muscle of Hindlimb Ischemia Model by Bubble Liposome and Ultrasound2010
- Author(s)
  Y.Negishi, Y.Endo-Takahashi, N.Takagi, R.Suzuki, K.Maruyama, Y.Aramaki
- Organizer
  International Liposome Research Days and Lipids, Liposomes, & Membrane Biophysics
- Place of Presentation
  University of British Columbia (Vancouver)
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] バブルリポソームと超音波技術の融合による下肢虚血モデルへのbFGF/SDF-1遺伝子導入効果の解析2010
- Author(s)
  根岸洋一,鈴木健太郎,遠藤葉子,高木教夫,鈴木亮,丸山一雄,新槇幸彦
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Development of AG73-modified Bubble liposomes as a vascular targeting ultrasound contrast agents2010
- Author(s)
  Y. Negishi, N. Hamano, Y. Endo-Takahashi, R. Suzuki, K. Maruyama, M. Nomizu, M. Emoto, Y. Aramaki
- Organizer
  The 2010 World Molecular Imaging Congress
- Place of Presentation
  Kyoto
- Year and Date
  2010-09-08
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] 新生血管を標的化するAG73ペプチド修飾バブルリポソームの作製と超音波造影効果の解析2010
- Author(s)
  濱野展人, 根岸洋一, 高橋葉子, 鈴木亮, 丸山一雄, 野水基義, Choijamts Batsuren, 江本精, 新槇幸彦
- Organizer
  遺伝子・デリバリー研究会第10回夏期セミナー
- Place of Presentation
  滋賀
- Year and Date
  2010-09-01
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] In vivo gene delivery system by Bubble liposomes and Ultrasound2010
- Author(s)
  Y. Negishi, Y. Endo-Takahashi, R. Suzuki, K. Maruyama, Y. Aramaki
- Organizer
  12th International Symposium on Ultrasound Contrast Imaging
- Place of Presentation
  Tokyo(招待講演)
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] AG73ペプチド修飾バブルリポソームを用いた新生血管を標的化する新規超音波造影剤の開発2010
- Author(s)
  濱野展人,根岸洋一,遠藤葉子,鈴木亮,丸山一雄,野水基義,Choijamts Batsuren,江本精,新槇幸彦
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Ultrasound-targeted Bubble Liposomes Destruction Enhances AG73-mediated Gene Transfer by Improvement of Intracellular Trafficking2010
- Author(s)
  D.Omata, Y.Negishi, Y.Endo-Takahashi, R.Suzuki, K.Maruyama, M.Nomizu, Y.Aramaki
- Organizer
  10^<th> International Symposium on Therapeutic Ultrasound
- Place of Presentation
  Tokyo
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Intramuscular Injection of Angiogenic Gene with Bubble Liposomes Followed by Ultrasound Exposure to Improve Angiogenesis2010
- Author(s)
  Y.Negishi, K. Matsuo, Y. Endo-Takahashi, K. Suzuki, Y. Matsuki, N. Takagi, R. Suzuki, K.Maruyama, Y.Aramaki,
- Organizer
  10th International Symposium on Therapeutic Ultrasound
- Place of Presentation
  Tokyo
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Ultrasound imaging of tumor model by AG73 peptide modified Bubble liposomes2010
- Author(s)
  N. Hamano, Y. Negishi, Y. Endo-Takahashi, R. Suzuki, K. Maruyama, M. Nomizu, C. Batsuren, M. Emoto, Y. Aramaki
- Organizer
  12th International Symposium on Ultrasound Contrast Imaging
- Place of Presentation
  Tokyo
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Enhanced Gene Delivery of AG73-modified Liposomes with Bubble Liposomes and Ultrasound Exposure by Improving Intracellular Trafficking2010
- Author(s)
  D.Omata, Y.Negishi, K.Suzuki, Y.Endo-Takahashi, R.Suzuki, K.Maruyama, M.Nomizu, Y.Aramaki
- Organizer
  International Liposome Research Days and Lipids, Liposomes, & Membrane Biophysics
- Place of Presentation
  University of British Columbia (Vancouver)
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] In vivo gene delivery system by Bubble liposomes and Ultrasound2010
- Author(s)
  Y.Negishi, Y.Endo-Takahashi, R.Suzuki, K.Maruyama, Y.Aramaki
- Organizer
  12th International Symposium on Ultrasound Contrast Imaging
- Place of Presentation
  Tokyo
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] bFGF Gene Transfer into Skeletal Muscle of Hindlimb Ischemia Model by Bubble Liposome and Ultrasound, International Liposome Research Days and Lipids2010
- Author(s)
  Y. Negishi, Y. Endo-Takahashi, N. Takagi, R.Suzuki, K. Maruyama, Y. Aramaki,
- Organizer
  Liposomes, & Membrane Biophysics
- Place of Presentation
  Vancouver
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Ultrasound-targeted Bubble Liposomes Destruction Enhances AG73-mediated Gene Transfer by Improvement of Intracellular Trafficking2010
- Author(s)
  D. Omata, Y.Negishi, Y. Endo-Takahashi, R. Suzuki, K.Maruyama, M. Nomizu, Y.Aramaki
- Organizer
  10th International Symposium on Therapeutic Ultrasound
- Place of Presentation
  Tokyo
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Intramuscular Injection of Angiogenic Gene with Bubble Liposomes Followed by Ultrasound Exposure to Improve Angiogenesis2010
- Author(s)
  Y.Negishi, K.Matsuo, Y.Endo-Takahashi, K.Suzuki, Y.Matsuki, N.Takagi, R.Suzuki, K.Maruyama, Y.Aramaki
- Organizer
  10^<th> International Symposium on Therapeutic Ultrasound
- Place of Presentation
  Tokyo
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Intravenous Delivery of pDNA and siRNA into Muscle with Bubble Liposomes and Ultrasound2009
- Author(s)
  Y.Negishi, S.Sekine, Y.Endo, N.Nishijima, R.Suzuki, K.Maruyama, Y, Aramaki
- Organizer
  9th International Symposium on Therapeutic Ultrasound
- Place of Presentation
  France
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] 超音波技術を利用した下肢虚血モデルへのbFGF/SDF-1遺伝子導入効果の解析2009
- Author(s)
  根岸洋一,松尾慶子,遠藤葉子,鈴木健太郎,高木教夫,鈴木亮,丸山一雄,新槇幸彦
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] 超音波エネルギーを利用した筋組織への経静脈的核酸導入法の検討2009
- Author(s)
  関根祥子、根岸洋一、西島信明、石井優子、遠藤葉子、鈴木亮、丸山一雄、新槇幸彦
- Organizer
  日本超音波医学会第82回学術集会
- Place of Presentation
  東京
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Intravenous Delivery of pDNA and siRNA into Muscle with Bubble Liposomes and Ultrasound2009
- Author(s)
  Y. Negishi, S. Sekine, Y. Endo, N. Nishijima, R. Suzuki, K. Maruyama, Y. Aramaki
- Organizer
  9th International Symposium on Therapeutic Ultrasound
- Place of Presentation
  Aix en Provence
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] Gene Transfer of bFGF into Skeletal Muscle of Murine Hindlimb Ischemia Model by Echo-contrast Gas Entrapping Liposomes2008
- Author(s)
  K. Matsuo, Y. Negishi, Y. Endo-Takahashi, N. Takagi, R. Suzuki, K. Maruyama, Y.Aramaki
- Organizer
  Bubble liposomes and Ultrasound 11th Liposome Research Days Conference
- Place of Presentation
  横浜
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-20300179
[Presentation] リポソームを用いたCpG-ODNの経鼻投与による粘膜免疫の賦活化2008
- Author(s)
  本庄絵美, 根岸洋一, 國澤純, 清野宏, 新槇幸彦
- Organizer
  第38 回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19590081
[Presentation] SPG-R8 を用いたCpG-ODN の経鼻投与による粘膜免疫の賦活化2007
- Author(s)
  高山典子, 根岸洋一, 國澤純, 清野宏, 櫻井和朗, 新槇幸彦
- Organizer
  第23 回日本DDS 学会
- Place of Presentation
  熊本
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19590081
[Presentation] Liposome を用いたCpG-ODN 経鼻投与による粘膜免疫の賦活化2007
- Author(s)
  高山典子, 本庄絵美, 根岸洋一, 國澤純, 清野宏, 新槇幸彦
- Organizer
  日本薬剤学会第22年会
- Place of Presentation
  大宮
- Year and Date
  2007-05-21
- Data Source
  KAKENHI-PROJECT-19590081
[Presentation] SPG-R8を用いたCpG-ODN の経鼻投与による粘膜アジュバント効果の増強. 遺伝子デリバリー研究会2007
- Author(s)
  高山典子, 河野麻子, 根岸洋一, 國澤純, 清野宏, 櫻井和朗, 新槇幸彦
- Organizer
  第7 回シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-19590081
[Presentation] バブルリポソームと集束超音波を併用した核酸導入法の基礎的検討
- Author(s)
  根岸洋一、山村翔、奥津大輔、高橋葉子、鈴木亮、丸山一雄、新槇幸彦
- Organizer
  第4回超音波分子診断治療研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300193
[Presentation] 筋ジストロフィー疾患治療のための超音波併用バブルリポソームによるアンチセンスデリバリーシステムの構築
- Author(s)
  間山　彩、根岸　洋一、秋山　早希、髙橋　葉子、鈴木　亮、丸山　一雄、新槇　幸彦
- Organizer
  第13回遺伝子・デリバリー研究会シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23300193
[]

1. NEGISHI Youichi (50286978)

# of Collaborated Projects: 6 results

# of Collaborated Products: 61 results
2. MARUYAMA Kazuo (30130040)

# of Collaborated Projects: 5 results

# of Collaborated Products: 56 results
3. TAKAGI Norio (50318193)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
4. TAKAHASHI Yoko (30453806)

# of Collaborated Projects: 4 results

# of Collaborated Products: 57 results
5. DAIKI OMATA

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. HAMANO NOBUHITO

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
7. NOMIZU Motoyoshi (00311522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. MORITASU Fuminori (80191055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TSUCHIYA Seishi (90057323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 多田塁 (70635888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
11. TAKAYAMA Noriko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. HONJOU Emi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. TSUNODA YUKA

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. MATSUO KEIKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
15. MATSUKI YUKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
16. TANONAKA Kouichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MARUNOUCHI Tetsuro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KATAGIRI Fumihiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. ISHII Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. OGURI Yukiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. SHIONO Hitomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
22. AKIYAMA Saki

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
23. MAYAMA Sayaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
24. KIKUCHI Taiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Aramaki Yukihiko 新槇 幸彦

ARAMAKI Yukihiko 新槇 幸彦

新槙 幸彦 アラマキ ユキヒコ

新槇 幸彦 アラマキ ユキヒコ

新〓 幸彦 アラマキ ユキヒコ

Research Projects

Research Products

Co-Researchers

Development of a nasal therapeutic vaccine to cervical cancer using liposomesPrincipal Investigator

Principal Investigator

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Research Institution

Therapeutic systems of muscular dystrophy by morpholino oligonucleotide-loaded nanobubble and ultrasound

Principal Investigator

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Research Category

Research Field

Research Institution

IL-6 acts as a key cytokine in the augmentation of mucosal immunity following intranasal administration of antigen with liposomesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene transfer system into mesenchymal stem cell by peptide-modified liposomes and ultrasound technology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Low invasive therapeutic system for vascular diseases by neovascular specific liposomes containing US-contrast gas

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of CpG-ODN for nasal vaccine developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規な超音波造影ガス封入リポソームによる非侵襲的虚血性血管再生療法のシステム開発

Principal Investigator

Project Period (FY)

Research Category

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オリゴヌクレオチドによる免疫応答の改変に関する研究Principal Investigator

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Ultrasound enhances gene expression of asialoglycoprotein receptor medieted gene transfer into hepatic cells

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Activation Mechanism of Macrophages by LiposomesPrincipal Investigator

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Elucidation of the Mechanism for Macrophage Activation induced by LiposomesPrincipal Investigator

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[Journal Article] Nasal vaccination with pneumococcal surface protein A in combination with cationic liposomes consisting of DOTAP and DC-chol confers antigen-mediated protective immunity against Streptococcus pneumoniae infections in mice2018

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[Journal Article] Intranasal administration of cationic liposomes enhanced granulocyte?macrophage colony-stimulating factor expression and this expression is dispensable for mucosal adjuvant activity2018

Aramaki Yukihiko 新槇幸彦

ARAMAKI Yukihiko 新槇幸彦

新槙幸彦アラマキユキヒコ

新槇幸彦アラマキユキヒコ

新〓幸彦アラマキユキヒコ