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Higuchi Hideo  樋口 秀男

ORCIDConnect your ORCID iD *help
… Alternative Names

HIDEO Higuchi  樋口 秀男

HIGUCHI Hideo  樋口 秀男

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Researcher Number 90165093
External Links
Affiliation (Current) 2025: 東北大学, 未来科学技術共同研究センター, 特任教授
Affiliation (based on the past Project Information) *help 2024: 東北大学, 未来科学技術共同研究センター, 特任教授
2015 – 2023: 東京大学, 大学院理学系研究科(理学部), 教授
2016: 東京大学, 理学部, 教授
2011 – 2016: 東京大学, 理学(系)研究科(研究院), 教授
2015: 東京大学, 大学院理学系研究科, 教授 … More
2014: 東京大学, 理学(系)研究科(研究院), 教授
2014: 東京大学, 理学部・物理学専攻, 教授
2013 – 2014: 東京大学, 理学系研究科, 教授
2011: 東京大学, 大学院・理学系研究科, 教授
2008 – 2009: The University of Tokyo, 大学院・理学系研究科, 教授
2004 – 2007: 東北大学, 先進医工学研究機構, 教授
2004: 東北大学, 大学院・工学研究科, 教授
1998 – 2004: 東北大学, 大学院・工学研究科, 助教授
2003: 東北大学, 工学研究科・金属工学専攻, 助教授
2002: 東北大学, 大学院・工学系研究科, 助教授
2001: 東北大学, 大学院・農学研究科, 助教授
1999: 東北大学, 大学院・工学研究所, 助教授 Less
Review Section/Research Field
Principal Investigator
Biophysics / Basic Section 43040:Biophysics-related / Biophysics / Biological Sciences / Molecular and Genome biology and related fields / Nanomaterials/Nanobioscience / Science and Engineering
Except Principal Investigator
Science and Engineering / Pathobiological dentistry/Dental radiology / Applied materials science/Crystal engineering … More / Condensed matter physics I / Applied microbiology / 応用微生物学・応用生物化学 / Laboratory medicine / General physiology / Biomedical engineering/Biological material science / Neurophysiology and muscle physiology / Science and Engineering / Biophysics Less
Keywords
Principal Investigator
1分子 / モータータンパク質 / 細胞 / キネシン / ダイニン / ミオシン / ナノ計測 / 振動 / 微小管 / kinesin … More / single molecules / ナノメートル / 非侵襲 / イメージング / in vivo / マウス / 運動 / 1粒子 / 運動タンパク質 / 1分子 / 心臓 / 鞭毛 / 心筋 / 生物物理 / メカニズム / 1分子計測 / 理論 / ステップ / 少数分子 / 分子モーター / 1分子計測 / 金微粒子 / 蛍光 / 金ナノ粒子 / 超解像 / ナノメートル精度 / 金コロイド / 超解像度 / STEP SIZE / SINGLE MOLECULES / DYNEIN / 原子分解能 / ステップサイズ / micro scope / motor protein / 蛍光顕微鏡 / nanotechnology / microtubule / 高輝度 / 量子ドット / Tatペプチド / エンドサイトーシス / 変位 / 力 / 単頭 / GFP / 好中球 / 幹細胞 / 筋肉 / がん細胞 / ナノメートル計測 / CdSe / 制御 / モーター / タンパク質分子 / 生体ナノシステム / ナノシステム / 低温 … More
Except Principal Investigator
Staphylococcus aureus / γ-hemolysin / 細胞・組織 / バイオイメージング / 膜孔形成 / leukocidin / 生物物理一般 / ナノバイオシステム / 生物物理学 / 分子心臓学 / 筋肉生理学 / 生理学 / 生物物理 / ナノバイオ / 微小管 / 粘膜免疫 / 外膜ヴェシクル / 免疫 / 歯周病 / Single molecule visualization / Laser confocal microscopy / Surface diffusion / Elementary growth steps / In situ observation / Lattice defects / Crystal growth / Protein / レーザー共焦点顕微鏡 / 1分子観察 / レーザー共焦点顕微法 / 表面拡散 / 単位成長ステップ / その場観察 / 格子欠陥 / 結晶成長 / タンパク質 / molecular decomposition / chemical transformation / size control / photo-electrochemical process / photo-catalyst / compound semiconductor / semiconducting particle / small particle / 硫化水素分解 / 硫化物半導体 / 分子分解 / 化学変換 / 粒径制御 / 光電気化学反応 / 光触媒 / 化合物半導体 / 半導体粒子 / 微小粒子 / Recognition of target cells / Pore-foming mechanism / two-component hemolytic toxin / 一分子技術 / 標的細胞認識 / 膜孔形成機構 / 2成分性溶血毒素 / γ-ヘモリジン / 黄色ブドウ球菌 / Assembly of toxin components / Single-molecule imaging / staphylococcal toxin / gamma-hemolysin / pore-forming toxin / 毒素成分集合 / 1分子イメージング / ブドウ球菌毒素 / 膜孔形成毒素 / FRET / 蛍光ナノ粒子 / HERファミリー / 乳癌 / ナノメディスン / in vivo / ナノイメージング / 細胞運動・形態形成・細胞間相互作用 / 生体ナノイメージング / 生体運動・形態形成・細胞間相互作用 / サルコメア / in vivoイメージング / ナノバイオロジー / 1分子イメージング・ナノ計測 / 医用画像・バイオイメージング / 生体情報・計測 / 医用物理学 / 1分子イメージング・ナノ計測 / 分子・細胞生理学 / 心筋 / 生体分子 / 反応パラメーター / 分子反応 / 化学反応パラメーター / 分子科学 / ナノマテリアル / 細胞・組織工学 / 細胞内動態 / ナノメディシン / ナノデバイス / 先端計測 / 生体材料 / 組織再生医療 / 細胞内診断 / 薬物送達システム / 分子イメージング / 細胞機能 / 細胞環境 / ナノメディシン分子科学 / 1分子計測 / 情報伝達 / 酸素反応 / 酵素反応 / 一分子計測 / 分子モーター / キネシン / 超高感度蛍光顕微鏡 / 一分子観察 / フリーラジカル / 細胞運動 / 共焦点顕微鏡 / 電子スピン共鳴 / 好中球内顆粒 / 光トラッピング / 共焦点レーザー顕微鏡 / 光合成細菌 / 電気化学顕微鏡 / 細胞活性 / イメージング / 分子内構造転移 / 溶媒応答性分子 / 分子スイッチ / 静電アクチュエータ / 情報伝達分子素子 / 人工筋肉 / エンタルピーエントロピー補償 / 分子間情報伝達 / タンパク水和 / タンパク分子モーター / 分子機械 / 筋肉 / 分光 / 光機能 / 1分子 / エバネッセント / 全反射蛍光顕微鏡 / 重合 / 合成 / 共役系高分子 Less
  • Research Projects

    (29 results)
  • Research Products

    (261 results)
  • Co-Researchers

    (60 People)
  •  Unified mechanism of oscillation and helical movements in proteins and cellsPrincipal Investigator

    • Principal Investigator
      樋口 秀男
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Tohoku University
      The University of Tokyo
  •  Measurement of oscillatory movements of biological systems and unified theory of the oscillationPrincipal Investigator

    • Principal Investigator
      Higuchi Hideo
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      The University of Tokyo
  •  imaging of whole cell by super resolution methodPrincipal Investigator

    • Principal Investigator
      Hideo Higuchi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Molecular and Genome biology and related fields
    • Research Institution
      The University of Tokyo
  •  Experimental and theoretical studies on function of single and multiple moleculesPrincipal Investigator

    • Principal Investigator
      Higuchi Hideo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biophysics
    • Research Institution
      The University of Tokyo
  •  Immunopathology of outer membrane vesicles of periodontopathic bacteria

    • Principal Investigator
      NAKAO Ryoma
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      National Institute of Infectious Diseases
  •  Basic construction for treatment effect prediction of molecular targeted drugs by quantitative estimation of HER family receptor based on highly sensitive nanoparticle imaging

    • Principal Investigator
      Ohuchi Noriaki
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory medicine
    • Research Institution
      Tohoku University
  •  Noninvasive Single molecule imaging in micePrincipal Investigator

    • Principal Investigator
      HIGUCHI Hideo
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biophysics
    • Research Institution
      The University of Tokyo
  •  Nanomedicine Molecular Science

    • Principal Investigator
      ISHIHARA KAZUHIKO
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  Imaging of molecular functions in cells with nanometer accuracy and constructing models to explain themPrincipal Investigator

    • Principal Investigator
      Higuchi Hideo
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  Single molecule physiology, inner molecules, molecules and cellsPrincipal Investigator

    • Principal Investigator
      HIDEO Higuchi
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biophysics
    • Research Institution
      The University of Tokyo
  •  Elucidation of cardiac excitation-contraction coupling by in vivo nano-imaging

    • Principal Investigator
      FUKUDA Norio
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Jikei University School of Medicine
  •  Development of molecular imaging technologies for the early diagnosis of heart disease

    • Principal Investigator
      FUKUDA Norio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Jikei University School of Medicine
  •  Analysis of cell dynamics using intravital nano-imaging.

    • Principal Investigator
      FUYU Kobirumaki
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General physiology
    • Research Institution
      Jikei University School of Medicine
  •  Regulation of Bio-nanosystemsPrincipal Investigator

    • Principal Investigator
      HIGUCHI Hideo
    • Project Period (FY)
      2004 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
      Tohoku University
  •  Regulatory Mechanism of nano-systems of motor proteinsPrincipal Investigator

    • Principal Investigator
      HIGUCHI Hideo
    • Project Period (FY)
      2004 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
      Tohoku University
  •  Chemical Transformation Networks using Ultra-small Particles

    • Principal Investigator
      KASUYA Atsuo
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Condensed matter physics I
    • Research Institution
      Tohoku University
  •  meaurment of single molecules of motor proteins with angustrome rsolutionPrincipal Investigator

    • Principal Investigator
      HIGUCHI Hideo
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Nanomaterials/Nanobioscience
    • Research Institution
      Tohoku University
  •  Studies on defect generation mechanisms in protein crystals by molecular-level in situ observations of elementary growth processes

    • Principal Investigator
      SAZAKI Gen
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied materials science/Crystal engineering
    • Research Institution
      Tohoku University
  •  従来型キネシン分子モーターの二足歩行モデルの直接検証

    • Principal Investigator
      廣瀬 恵子
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biophysics
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Bacterial Two-component and Hetero-heptameric Pore-forming Cytolytic Toxins : Structures, Pore-forming Mechanism

    • Principal Investigator
      KAMIO Yoshiyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied microbiology
    • Research Institution
      Tohoku University
  •  Staphylococcal pore-forming toxins: Mechanism of pore-forming and recognition of the target cells

    • Principal Investigator
      KAMIO Yoshiyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Tohoku University
  •  The development of artifical cell motility and analysis of 3D motilityPrincipal Investigator

    • Principal Investigator
      HIGUCHI Hideo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biophysics
    • Research Institution
      TOHOKU UNIVERSITY
  •  高時間分解低温ナノ顕微鏡でキネシン1分子のステップの中を見るPrincipal Investigator

    • Principal Investigator
      樋口 秀男
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  新規蛍光ポリマーの合成と表面エバネッセント光による単一分子機能イメージング

    • Principal Investigator
      篠原 健一
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  低温ナノ顕微鏡の開発とキネシン1分子の運動の解析Principal Investigator

    • Principal Investigator
      樋口 秀男
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  モータータンパクのシンクロ運動機構とそのモデル化

    • Principal Investigator
      鈴木 誠
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University
  •  単一細胞バイアビリティイメージング

    • Principal Investigator
      末永 智一
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University
  •  低温ナノ顕微鏡の開発とキネシン1分子の分子内運動の観察Principal Investigator

    • Principal Investigator
      樋口 秀男
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  Inducing the movement of single kinesin molecules by the asymmetric artificial pertarbation.Principal Investigator

    • Principal Investigator
      HIGUCHI Hideo
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Biophysics
    • Research Institution
      TOHOKU UNIVERSITY

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All Journal Article Presentation Book Patent

  • [Book] Handbook of dynein 2nd.2019

    • Author(s)
      H. Higuchi and C. Shingyoji.
    • Total Pages
      436
    • Publisher
      Pan Stanford Publishing
    • ISBN
      9814800015
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Book] Handbook of dynein2018

    • Author(s)
      H. Higuchi and C. Shingyoji
    • Total Pages
      300
    • Publisher
      Pan Stanford Publishing
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Book] 1分子生物学2014

    • Author(s)
      樋口秀男,多田隈尚史
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-23247022
  • [Book] 1分子生物学2014

    • Author(s)
      樋口秀男,多田隈尚史
    • Total Pages
      304
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Book] Handbook of Dynein2012

    • Author(s)
      Y Toyoshima and H. Higuchi
    • Total Pages
      20
    • Publisher
      Motile and Enzymatic properties of native dynein molecules
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Book] Handbook of Dynein2012

    • Author(s)
      豊島陽子、樋口秀男
    • Total Pages
      18
    • Publisher
      Pan Stanford Publishing Pte.Ltd
    • Data Source
      KAKENHI-PROJECT-23247022
  • [Book] 先端バイオマテリアルハンドブック2012

    • Author(s)
      樋口秀男、権田幸祐
    • Total Pages
      656
    • Publisher
      NTS 出版
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Book] 実験医学増刊Vol.26 No.17生命現象の動的理解を目指すライブイメージング2008

    • Author(s)
      樋口秀男
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Book] 実験医学増刊Vol.26 No.17生命現象の動的理解を目指すライブイメージング2008

    • Author(s)
      樋口秀男
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Book] 生命現象の動的理解を目指すライブイメージング(ナノメディシン)2008

    • Author(s)
      樋口秀男
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Book] 単一量子ドットのバイオ・医療ナノイメージング2008

    • Author(s)
      樋口秀男
    • Publisher
      Ohmsha ナノメディシン
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Book] 単一量子ドットのバイオ・医療ナノイメージング(ナノメディシン)2008

    • Author(s)
      樋口秀男
    • Publisher
      Ohmsha
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Book] 「生命現象の動的理解を目指すライブイメージング」 実験医学増刊Vol.262008

    • Author(s)
      樋口秀男
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Book] 非侵襲・可視化技術ハンドブック2007

    • Author(s)
      樋口秀男
    • Publisher
      NTS出版
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Book] 「量子ドットを用いたがん細胞の単一分子イメージング」 量子ドットの生命科学領域への応用2007

    • Author(s)
      樋口秀男
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Book] 非侵襲・可視化技術ハンドブック2007

    • Author(s)
      樋口秀男
    • Publisher
      NTS出版
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Book] 分子モーター概論(生物物理学ハンドブック)2007

    • Author(s)
      樋口秀男
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Book] 生物物理学ハンドブック2007

    • Author(s)
      樋口秀男
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Book] 「生体分子モーター」 非侵襲・可視化技術ハンドブック2007

    • Author(s)
      樋口秀男
    • Publisher
      NTS出版
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Book] 量子ドットの生命科学領域への応用2007

    • Author(s)
      樋口秀男
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Book] 量子ドットを用いたがん細胞の単一分子イメージング(量子ドットの生命科学領域への応用)2007

    • Author(s)
      樋口秀男
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Book] 量子ドットの生命科学領域への応用2007

    • Author(s)
      樋口秀男
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Book] 「分子モーター概論」 生物物理学ハンドブック2007

    • Author(s)
      樋口秀男
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Book] 生体分子モーター(非侵襲・可視化技術ハンドブック)2007

    • Author(s)
      樋口秀男
    • Publisher
      NTS出版
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Book] 生物物理学ハンドブック2007

    • Author(s)
      樋口秀男
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Versatile properties of dynein molecules underlying regulation in flagellar oscillation.2023

    • Author(s)
      Takashi Fujiwara, Chikako Shingyoji and Hideo Higuchi
    • Journal Title

      Sci. Rep.

      Volume: 13 Issue: 1 Pages: 1-15

    • DOI

      10.1038/s41598-023-37242-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K23844
  • [Journal Article] Fast backward steps and detachment of single kinesin molecules measured under a wide range of loads.2023

    • Author(s)
      Yuichi Kondo, Kazuo Sasaki and Hideo Higuchi
    • Journal Title

      Traffic

      Volume: 24 Issue: 10 Pages: 463-474

    • DOI

      10.1111/tra.12909

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K23844
  • [Journal Article] Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami2022

    • Author(s)
      Abdellatef Shimaa A、Tadakuma Hisashi、Yan Kangmin、Fujiwara Takashi、Fukumoto Kodai、Kondo Yuichi、Takazaki Hiroko、Boudria Rofia、Yasunaga Takuo、Higuchi Hideo、Hirose Keiko
    • Journal Title

      eLife

      Volume: 11 Pages: 1-20

    • DOI

      10.7554/elife.76357

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20J23072, KAKENHI-PROJECT-23K23844
  • [Journal Article] Automation of detecting and tracking3D vesicle transport using dual-focus optics2022

    • Author(s)
      Seohyun Lee, Hyuno Kim, and Hideo Higuchi
    • Journal Title

      SPIE Photonics West BiOS 2023

      Volume: 123850E Pages: 1-4

    • DOI

      10.1117/12.2649474

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K23844
  • [Journal Article] 物理学科における生物物理学生実験の光学測定教材実験の開発2021

    • Author(s)
      佐伯喜美子, 八幡和志, 茅元司, 樋口秀男
    • Journal Title

      Physics Education in University

      Volume: 27 Issue: 3 Pages: 159-162

    • DOI

      10.11316/peu.27.3_159

    • NAID

      130008129509

    • ISSN
      1340-993X, 2432-1710
    • Year and Date
      2021-11-15
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Journal Article] Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami2021

    • Author(s)
      3.Keiko Hirose, Hideo Higuchi, Shimaa A Abdellatef, Hisashi Tadakuma, Kangmin Yan, Takashi Fujiwara, Kodai Fukumoto, Yuichi Kondo, Hiroko Takazaki, Rofia Boudria, Takuo Yasunaga
    • Journal Title

      biorxiv

      Volume: なし Pages: 1-23

    • DOI

      10.1101/2021.12.06.471346

    • Open Access
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Journal Article] A reverse stroke characterizes the force generation of cardiac myofilaments, leading to an understanding of heart function.2021

    • Author(s)
      Yongtae Hwang, Takumi Washio, ProfileToshiaki Hisada, Hideo Higuchi, and Motoshi Kaya.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 118 Issue: 23 Pages: 1-11

    • DOI

      10.1073/pnas.2011659118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Journal Article] Classification of Metastatic Breast Cancer Cell using Deep Learning Approach2021

    • Author(s)
      Seohyun Lee, Hyuno Kim, Hideo Higuchi, and Masatoshi Ishikawa.
    • Journal Title

      IEEE ICAIIC

      Volume: 2021 Pages: 425-428

    • DOI

      10.1109/icaiic51459.2021.9415245

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Journal Article] Visualization Method for the Cell-Level Vesicle Transport Using Optical Flow and a Diverging Colormap2021

    • Author(s)
      Lee Seohyun、Kim Hyuno、Higuchi Hideo、Ishikawa Masatoshi
    • Journal Title

      Sensors

      Volume: 21 Issue: 2 Pages: 1-13

    • DOI

      10.3390/s21020522

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K15753, KAKENHI-PROJECT-20H05704, KAKENHI-PROJECT-19K23717, KAKENHI-PROJECT-19H03189
  • [Journal Article] Visualization and Data Analysis for Intracellular Transport using Computer Vision Tech-niques2020

    • Author(s)
      Seohyun Lee, Hyuno Kim, Hideo Higuchi, Masatoshi Ishikawa
    • Journal Title

      2020 IEEE Sensors Applications Symposium.

      Volume: 1 Pages: 1-6

    • DOI

      10.1109/sas48726.2020.9220026

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Journal Article] Mechanism of contraction rhythm homeostasis for hyperthermal sarcomeric oscillations of neonatal cardiomyocytes2020

    • Author(s)
      Seine A. Shintani., Takumi Washio and Hideo Higuchi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 20468-20468

    • DOI

      10.1038/s41598-020-77443-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K15762, KAKENHI-PROJECT-19H03189
  • [Journal Article] Heterogeneous drug efficacy of an antibody-drug conjugate visualized using simultaneous imaging of its delivery and intracellular damage in living tumor tissues.2020

    • Author(s)
      Gonda K, Negishi H, Takano-Kasuya M, Kitamura N, Furusawa N, Nakano Y, Hamada Y, Tokunaga M, Higuchi H, Tada H, Ishida T.
    • Journal Title

      Translational Oncology

      Volume: 13 Issue: 6 Pages: 100764-100764

    • DOI

      10.1016/j.tranon.2020.100764

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22549, KAKENHI-PROJECT-19H03189
  • [Journal Article] Optical flow of vesicles: computer vision approach for endocytosis of Nano Particles in a living cell.2020

    • Author(s)
      Seohyun Lee*, Hyuno Kim, Hideo Higuchi, and Masatoshi Ishikawa.
    • Journal Title

      SPIE BiOS

      Volume: 112541J Pages: 1-6

    • DOI

      10.1117/12.2543455

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Journal Article] 3D rotational motion of an endocytic vesicle on a complex microtubule network in a living cell2019

    • Author(s)
      1.Seohyun Lee and Hideo Higuchi
    • Journal Title

      bioRxiv

      Volume: 576702 Pages: 1-12

    • DOI

      10.1101/576702

    • Open Access
    • Data Source
      KAKENHI-PROJECT-17K19343, KAKENHI-PROJECT-16H04773
  • [Journal Article] Effect of myofibril passive elastic properties on the mechanical communication between mo-tor proteins on adjacent sarcomeres.2019

    • Author(s)
      9.Takumi Washio*, Seine A. Shintani, Hideo Higuchi, Seiryo Sugiura and Toshiaki Hisada.
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41598-019-45772-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03189, KAKENHI-PROJECT-17K15102
  • [Journal Article] Cationic Copolymer‐Chaperoned 2D?3D Reversible Conversion of Lipid Membranes2019

    • Author(s)
      Shimada Naohiko、Kinoshita Hirotaka、Umegae Takuma、Azumai Satomi、Kume Nozomi、Ochiai Takuro、Takenaka Tomoka、Sakamoto Wakako、Yamada Takayoshi、Furuta Tadaomi、Masuda Tsukuru、Sakurai Minoru、Higuchi Hideo、Maruyama Atsushi
    • Journal Title

      Advanced Materials

      Volume: 31 Issue: 44 Pages: 1904032-1904032

    • DOI

      10.1002/adma.201904032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H01807, KAKENHI-PROJECT-18K18384, KAKENHI-PROJECT-19H03189, KAKENHI-PROJECT-18J13337
  • [Journal Article] 3D rotational motion of an endocytic vesicle on a complex microtubule network in a liv-ing cell. Biomed.2019

    • Author(s)
      Seohyun Lee and Hideo Higuchi
    • Journal Title

      Biomed. Opt. Exp.

      Volume: 10 Issue: 12 Pages: 6611-6624

    • DOI

      10.1364/boe.10.006611

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19343, KAKENHI-PROJECT-19H03189
  • [Journal Article] ファイマンラチェット-生体分子の運動の理解にむけて-2018

    • Author(s)
      樋口秀男
    • Journal Title

      数理科学

      Volume: 633 Pages: 34-39

    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Journal Article] Focus Stabilization by Axial Position Feedback in Biomedical Imaging Microscopy2018

    • Author(s)
      Seohyun Lee, Hyuno Kim, Hideo Higuchi
    • Journal Title

      IEEE Sensors Applications Symposium

      Volume: 2018 Pages: 309-314

    • DOI

      10.1109/sas.2018.8336767

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19343, KAKENHI-PROJECT-16H04773
  • [Journal Article] A unified walking model for dimeric motor proteins2018

    • Author(s)
      K. Sasaki, M. Kaya, and H. Higuchi.
    • Journal Title

      Biophys. J.

      Volume: 115 Issue: 10 Pages: 1-12

    • DOI

      10.1016/j.bpj.2018.09.032

    • NAID

      130007648128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19343, KAKENHI-PROJECT-16H04773
  • [Journal Article] Step Sizes and Rate Constants of Single-headed Cytoplasmic Dynein Measured with Optical Tweezers2018

    • Author(s)
      Yoshimi Kinoshita, Taketoshi Kambara, Kaori Nishikawa, Motoshi Kaya and Hideo Higuchi
    • Journal Title

      Sci. Rep

      Volume: 16333 Issue: 1 Pages: 1-13

    • DOI

      10.1038/s41598-018-34549-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19343, KAKENHI-PROJECT-16H04773
  • [Journal Article] ファイマンラチェット-生体分子の運動の理解にむけて-2018

    • Author(s)
      樋口秀男
    • Journal Title

      数理科学

      Volume: 56 Pages: 34-39

    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Journal Article] Numerical method for vesicle movement analysis in a complex cytoskeleton network.2018

    • Author(s)
      Seohyun Lee, Hyuno Kim, Hideo Higuchi.
    • Journal Title

      Opt. Express

      Volume: 26 Issue: 13 Pages: 16236-16239

    • DOI

      10.1364/oe.26.016236

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19343, KAKENHI-PROJECT-16H04773
  • [Journal Article] Coordinated force generation of skeletal myosins in myofilaments through motor coupling.2017

    • Author(s)
      Motoshi Kaya*, Yoshiaki Tani, Takumi Washio, Toshiaki Hisada and Hideo Higuchi
    • Journal Title

      Nature Communications

      Volume: 16036 Issue: 1 Pages: 1-14

    • DOI

      10.1038/ncomms16036

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Journal Article] Analysis of spontaneous oscillations for a three state power stroke model2016

    • Author(s)
      Takumi Washio, Seine A. Shintani, Hideo Higuchi and Toshiaki Hisada
    • Journal Title

      Physical Review E

      Volume: 22 Issue: 2 Pages: 473-482

    • DOI

      10.1103/physreve.95.022411

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23107002, KAKENHI-PROJECT-15J07373, KAKENHI-PROJECT-16H04773
  • [Journal Article] Quantitative evaluation of malignant gliomas damage induced by photoactivation of IR700 dye2016

    • Author(s)
      Morito Sakuma, Sayaka Kita and Hideo Higuchi
    • Journal Title

      Science and Technology of Advanced Materials

      Volume: 17 Issue: 1 Pages: 473-482

    • DOI

      10.1080/14686996.2016.1205936

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23107002, KAKENHI-WRAPUP-16H01692, KAKENHI-PROJECT-16J07114, KAKENHI-PROJECT-16H04773
  • [Journal Article] Predictive diagnosis of the risk of breast cancer recurrence after surgery by single-particle quantum dot imaging.2015

    • Author(s)
      Gonda K, Miyashita M, Higuchi H, Tada H, Watanabe TM, Watanabe M, Ishida T, Ohuchi N.
    • Journal Title

      Scientific Report.

      Volume: 22(5) Issue: 1 Pages: 14322-14322

    • DOI

      10.1038/srep14322

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15108, KAKENHI-PLANNED-23115002, KAKENHI-PLANNED-23107009, KAKENHI-PLANNED-23107002, KAKENHI-PROJECT-26291028
  • [Journal Article] Dynein arms are strain-dependent direction-switching force generators.2015

    • Author(s)
      Shingyoji, C., Nakano, I., Inoue, Y. and Higuchi, H.
    • Journal Title

      Cytoskeleton

      Volume: 72 Issue: 8 Pages: 388-401

    • DOI

      10.1002/cm.21232

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-26102510, KAKENHI-PROJECT-25440062, KAKENHI-PROJECT-25291072, KAKENHI-PLANNED-23107002
  • [Journal Article] 生物の普遍性2015

    • Author(s)
      樋口秀男
    • Journal Title

      生物物理学会誌

      Volume: 55 Pages: 285-285

    • NAID

      130005110033

    • Open Access
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Journal Article] Nano-scale measurement of biomolecules by optical microscopy and semiconductor nanoparticles2014

    • Author(s)
      Taro Ichimura, Takashi Jin, Hideaki Fujita, Hideo Higuchi, Tomonobu M. Watanabe
    • Journal Title

      Front. Physiol., fphys.

      Volume: 5 Pages: 1-13

    • DOI

      10.3389/fphys.2014.00273

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23115002, KAKENHI-PROJECT-25650047, KAKENHI-PROJECT-26840057, KAKENHI-PLANNED-23107002
  • [Journal Article] A novel approach for purification and selective capture of membrane vesicles of the periodontopathic bacterium, Porphyromonas gingivalis: membrane vesicles bind to magnetic beads coated with epoxy groups in a noncovalent, species-specific manner.2014

    • Author(s)
      Nakao R, Kikushima K, Higuchi H, Obana N, Nomura N, Bai D, Ohnishi M, Senpuku H.
    • Journal Title

      PLoS One.

      Volume: 9 Issue: 5 Pages: 1-10

    • DOI

      10.1371/journal.pone.0095137

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J00321, KAKENHI-PROJECT-22791822, KAKENHI-PROJECT-23247022, KAKENHI-PROJECT-25650105, KAKENHI-PROJECT-26462866, KAKENHI-PROJECT-26860281, KAKENHI-PLANNED-23107002
  • [Journal Article] 歩行型分子モーター,ダイニン2013

    • Author(s)
      神原丈敏、樋口,秀男
    • Journal Title

      パリティ

      Volume: 28 Pages: 14-16

    • Data Source
      KAKENHI-PROJECT-23247022
  • [Journal Article] Stiffness, working stroke and force of single myosins in skeletal muscle: Elucidation of these mechanical properties by non-linear elasticity2013

    • Author(s)
      Kaya. M. and H. Higuchi
    • Journal Title

      Cell and Mol. life Sci

      Volume: 70 Issue: 22 Pages: 4275-4292

    • DOI

      10.1007/s00018-013-1353-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23107002, KAKENHI-PROJECT-23247022, KAKENHI-PROJECT-24540430
  • [Journal Article] A non-invasive imaging for the in vivo tracking of high-speed vesicle transport in mouse neutrophils2013

    • Author(s)
      3.Kenji Kikushima, Sayaka Kita and Hideo Higuchi
    • Journal Title

      Scientific reports

      Volume: 3 Issue: 1 Pages: 1-10

    • DOI

      10.1038/srep01913

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23107002, KAKENHI-PROJECT-23247022, KAKENHI-PROJECT-23770171
  • [Journal Article] Single quantum dot tracking reveals that an individual multivalent 2 HIV-1 Tat-protein transduction domain can activate machinery for 3 lateral transport and endocytosis2013

    • Author(s)
      3.Yasuhiro Suzuki*, Chandra Nath Roy, Warunya Promjunyaku, Hiroyasu Hatakeyama, Kohsuke Gonda, Junji Imamura, Biju Vasudevan Pillai, Noriaki Ohuchi, Makoto Kanzaki , Hideo Higuchi, and Mitsuo Kaku
    • Journal Title

      Mol. Cell Biol.

      Volume: 33 Issue: 15 Pages: 3039-3049

    • DOI

      10.1128/mcb.01717-12

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23107002, KAKENHI-PLANNED-23107009, KAKENHI-PROJECT-23247022, KAKENHI-PROJECT-25293074, KAKENHI-PROJECT-25713010
  • [Journal Article] 筋肉の巧みな収縮メカニズム2012

    • Author(s)
      茅元司,樋口秀男
    • Journal Title

      感染・炎症・免疫

      Volume: 42 Pages: 116-123

    • Data Source
      KAKENHI-PROJECT-23247022
  • [Journal Article] ナノバイオ2011

    • Author(s)
      樋口秀男
    • Journal Title

      理大科学フォーラム

      Volume: 8 Pages: 19-24

    • Data Source
      KAKENHI-PLANNED-23107002
  • [Journal Article] Thin filament-reconstituted skinned muscle fibers for the study of muscle physiology.2011

    • Author(s)
      Higuchi S
    • Journal Title

      J Biomed Biotechnol.

      Volume: 2011 Issue: 1 Pages: 486021-486021

    • DOI

      10.1155/2011/486021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300130, KAKENHI-PLANNED-23107003, KAKENHI-PUBLICLY-23136515, KAKENHI-PROJECT-23300146
  • [Journal Article] Thin filament-reconstituted skinned muscle fibers for the study of muscle physiology2011

    • Author(s)
      Higuchi S, Yoshikazu T, Fukuda N, Kurihara S, Fujita H
    • Journal Title

      Journal of Biomedicine and Biotechnology

      Volume: 2011 Pages: 486021-486021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650274
  • [Journal Article] マウス個体内の1分子計測2011

    • Author(s)
      樋口秀男
    • Journal Title

      現代化学

      Volume: 488 Pages: 46-47

    • Data Source
      KAKENHI-PLANNED-23107002
  • [Journal Article] ナノバイオ2011

    • Author(s)
      樋口秀男
    • Journal Title

      理大科学フォーラム

      Volume: 8 Pages: 19-24

    • Data Source
      KAKENHI-PROJECT-23247022
  • [Journal Article] In Vivo Nano-imaging of Membrane Dynamics in Metastatic Tumor Cells Using Quantum Dots2010

    • Author(s)
      K Gonda, T M. Watanabe N. Ohuchi, *H. Higuchi
    • Journal Title

      J. Biol. chem 285

      Pages: 2750-2757

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Systematic comparison of In vitro motile properties between chlamydomonas wild-type and mutant outer arm dyneins each lacking one of the three heavy chain2009

    • Author(s)
      Furuta A., T. Yagi, H. Yanagisawa, H. Higuchi, and R. Kamiya
    • Journal Title

      J. Biol. Chem. 284

      Pages: 5927-5935

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Systematic comparison of In vitro motile properties between chlamydomonas wild-type and mutant outer arm dyneins each lacking one of the three heavy chain2009

    • Author(s)
      Furuta A., T. Yagi, H. Yanagisawa, H. Higuchi, *R. Kamiya
    • Journal Title

      J. Biol. Chem 284

      Pages: 5927-5935

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Single-Molecule Visualization of Diffusion at the Solution-Crystal Interface2008

    • Author(s)
      Sazaki, G., M. Okada, T. Matsui, T. Watanabe, H. Higuchi, K. Tsukamoto, K. Nakajima
    • Journal Title

      Crtstal Growth and Design 8

      Pages: 2024-2031

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Single-Molecule Visualization of Diffusion at the Solution-Crystal Interface2008

    • Author(s)
      Sazaki,G., M.Okada, T. Matsui, T. Watanabe, H. Higuchi, K. Tsukamoto and K. Nakajima
    • Journal Title

      Crtstal Growth and Design 8

      Pages: 2024-2031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Intracellular imaging of targeted proteins la-beled with Quantum Dots2008

    • Author(s)
      Yoo J., T. Kambara, K. Gonda, *H. Higuchi
    • Journal Title

      Exp Cell Res 314

      Pages: 3563-3569

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Intracellular imaging of targeted proteins la-beled with Quantum Dots2008

    • Author(s)
      Yoo J., T. Kambara, K. Gonda, and H. Higuchi
    • Journal Title

      Exp Cell Res. 314

      Pages: 3563-3569

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Human Myosin Vc Is a Low Duty Ratio Nonprocessive Motor2008

    • Author(s)
      Watanabe S., T.M. Watanabe, O. Sato, J. Awata, K. Homma, N. Umeki, H. Higuchi, R. Ikebe, *M. Ikebe
    • Journal Title

      J. Biol. Chem 283

      Pages: 10581-10592

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Human Myosin Vc Is a Low Duty Ratio Nonprocessive Motor2008

    • Author(s)
      Watanabe S., T.M. Watanabe, O. Sato, J. Awata, K. Homma, N. Umeki, H. Higuchi, R. Ikebe, and M. Ikebe
    • Journal Title

      J. Biol. Chem. 283

      Pages: 10581-10592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] In vivo Real-time Tracking of Single Quantum Dots Conjugated with Monoclonal Anti-HER2 Antibody in Tumors of Mice2007

    • Author(s)
      H. Tada, *H. Higuchi, T.M. Wanatabe, N. Ohuchi
    • Journal Title

      Cancer Res. 67

      Pages: 1138-44

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Stepwise Movements in Vesicle Transport of HER2 by Motor Protein in Living Cells2007

    • Author(s)
      T.M. Watanabe and H. Higuchi
    • Journal Title

      Biophysical Journal 92

      Pages: 4109-4120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] In vivo Real-time Tracking of Single Quantum Dots Conjugated with Monoclonal Anti-HER2 Antibody in Tumors of Mice2007

    • Author(s)
      H. Tada, H. Higuchi, T. M. Wanatabe, and N. Ohuchi
    • Journal Title

      Cancer Res. 67

      Pages: 1138-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Stepwise Movements in Vesicle Transport of HER2 by Motor Protein in Living Cells2007

    • Author(s)
      T. M. Watanabe and H. Higuchi
    • Journal Title

      Biophysical Journal 92

      Pages: 4109-4120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Stepwise Movements in Vesicle Transport of HER2 by Motor Proteins in Living Cells2007

    • Author(s)
      Watanabe, T.M. and H. Higuchi
    • Journal Title

      Biophysical J. 92

      Pages: 1-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Three-dimensional nanometry of vesicle transport in a living cell using dual-focus imaging optics2007

    • Author(s)
      Watanabe, T. M., T. Sato, K. Gonda and H. Higuchi
    • Journal Title

      Biochem. Biophys. Res. Comm. (In Press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Stepwise Movements in Vesicle Transport of HER2 by Motor Proteins in Living Cells2007

    • Author(s)
      Watanabe, T.M., *H. Higuchi
    • Journal Title

      Biophysical J. 92

      Pages: 1-12

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Three-dimensional nanometry of vesicle transport in a living cell using dual-focus imaging optics2007

    • Author(s)
      Watanabe, T.M., T. Sato, K. Gonda, *H. Higuchi
    • Journal Title

      Biochem. Biophys. Res. Comm. In press

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Single-Molecule visualization of Enviroment-Sensitive Fluorophores Inserted into cell membranes by Staphylococcal gamma-hemolysin.2006

    • Author(s)
      Nguyen, A.H., Nguyen, V.T., Kamio, Y., Higuchi, H.
    • Journal Title

      Biochemistry 45(8)

      Pages: 2570-2576

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310082
  • [Journal Article] Reduction in nonfluorescence state of quantum dots on an immunofluorescence staining2006

    • Author(s)
      S. Li-Shishido, T.M. Watanabe, H. Tada, *H. Higuchi, N. Ohuchi
    • Journal Title

      Biochem. Biophys. Res. Comm. 351

      Pages: 7-13

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] バイオナノイメージングとナノ医療2006

    • Author(s)
      樋口秀男 他
    • Journal Title

      応用物理 75 (6)

      Pages: 694-698

    • NAID

      10019172511

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Single-Molecule Visuarization of Enviroment-Sensitive Fluorophores Inserted into cell membranes by Staphylococcal gamma-hemolysin2006

    • Author(s)
      A. H. Nguyen, V. T. Nguyen, Y. Kamio and H. Higuchi
    • Journal Title

      Biochemistry 45

      Pages: 2570-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] 蛍光性量子ドットによるがん細胞の単一分子ナノイメージング2006

    • Author(s)
      樋口秀男 他
    • Journal Title

      バイオテクノロジージャーナル 12月号

      Pages: 30-35

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Overlapping hand-over-hand mechanism of single molecular motility of cytoplasmic dynein2006

    • Author(s)
      S. Toba, T. M. Watanabe, L-Y Okimoto, Y. Y. Toyoshima and H. Higuchi
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 103

      Pages: 5741-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Single-Molecule Visuarization of Enviroment-Sensitive Fluorophores Inserted into cell membranes by Staphylococcal gamma-hemolysin2006

    • Author(s)
      A.H. Nguyen, V.T. Nguyen, Y. Kamio, H. Higuchi.
    • Journal Title

      Biochemistry 45

      Pages: 2570-6

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Reduction in nonfluorescence state of quantum dots on an immunofluorescence staining2006

    • Author(s)
      S. Li-Shishido, T. M. Watanabe, H. Tada, H. Higuchi and N. Ohuchi
    • Journal Title

      Biochem. Biophys. Res. Comm. 351

      Pages: 7-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Overlapping hand-over-hand mechanism of single molecular motility of cytoplasmic dynein2006

    • Author(s)
      S. Toba, T.M. Watanabe, L-Y Okimoto, Y.Y. Toyoshima, *H. Higuchi
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 103

      Pages: 5741-45

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] バイオナノイメージングとナノ医療2006

    • Author(s)
      樋口秀男 他
    • Journal Title

      応用物理 75 (6)

      Pages: 694-698

    • NAID

      10019172511

    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] 蛍光性量子ドットによるがん細胞の単一分子ナノイメージング2006

    • Author(s)
      樋口秀男 他
    • Journal Title

      バイオテクノロジージャーナル 12月号

      Pages: 30-35

    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] チャールズ・デイ「DNAからRNAへの遺伝子情報転写のステップ運動をとらえた」訳2006

    • Author(s)
      チャールズ・デイ, 樋口秀男訳
    • Journal Title

      パリティ 21 (5)

      Pages: 32-34

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] 生体分子モーターの1分子力学計測2006

    • Author(s)
      樋口秀男
    • Journal Title

      パリティ 22 (1)

      Pages: 47-48

    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Overlapping hand-over-hand mechanism of single molecular motility of cytoplasmic dynein.2006

    • Author(s)
      S.Toba, T.M.Watanabe, L-Y Okimoto, Y.Y.Toyoshima, H.Higuchi.
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 103

      Pages: 5741-5745

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310082
  • [Journal Article] 生体分子モーターの1分子力学計測2006

    • Author(s)
      樋口秀男
    • Journal Title

      パリティ 22 (1)

      Pages: 47-48

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] チャールズ・デイ「DNAからRNAへの遺伝子情報転写のステップ運動をとらえた」訳2006

    • Author(s)
      チャールズ・デイ, 樋口秀男訳
    • Journal Title

      パリティ 21 (5)

      Pages: 32-34

    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Biased Binding of Single Molecules and Continuous Movement of Multiple Molecules of Truncated Single-Headed Kinesin.2005

    • Author(s)
      Takashi Kamei, Seiji Kakuta, Hideo Higuchi.
    • Journal Title

      Biophysical Journal 88

      Pages: 2068-2077

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310082
  • [Journal Article] Motility of myosin V regulated by the dissociation of single calmodulin2005

    • Author(s)
      Nguyen HoaAnh and Hideo Higuchi
    • Journal Title

      Nature Struct Mol Biol 12

      Pages: 127-132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Motility of myosin V regulated by the dissociation of single calmodulin2005

    • Author(s)
      Nguyen HoaAnh, *Hideo Higuchi
    • Journal Title

      Nature Struct Mol Biol 12

      Pages: 127-132

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Biased Binding of Single Molecules and Continuous Movement Of Multiple Molecules of Truncated Single-Headed Kinesin2005

    • Author(s)
      Takashi Kamei, Seiji Kakuta and Hideo Higuchi
    • Journal Title

      Biophysical Journal 88

      Pages: 2068-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] ナノバイオからナノ医学へ2005

    • Author(s)
      樋口秀男
    • Journal Title

      ナノ学会会報

      Pages: 35-41

    • NAID

      40006668513

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Biased Binding of Single Molecules and Continuous Movement Of Multiple Molecules of Truncated Single-Headed Kinesin2005

    • Author(s)
      Takashi Kamei, Seiji Kakuta, *Hideo Higuchi
    • Journal Title

      Biophysical Journal 88

      Pages: 2068-77

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] W177 and R198, of LukF for Phosphatidylcholine-Binding and Pore-Formation by Staphylococcal {gamma}-Hemolysin on Human Erythrocyte Membranes2004

    • Author(s)
      Monma N, Nguyen VT, Kaneko J, Higuchi H, *Kamio Y. Essential Residues
    • Journal Title

      J Biochem (Tokyo). 136

      Pages: 427-431

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Rapid double 8-nm steps by a kinesin mutant2004

    • Author(s)
      Higuchi H, Bronner CE, Park HW, *Endow SA
    • Journal Title

      EMBO J 23

      Pages: 2993-9

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Regional rheological differences in locomoting neutrophils.2004

    • Author(s)
      Yanai, M.J.P.Butler, T.Suzuki., H.Sasaki, H.Higuchi.
    • Journal Title

      Am.J.Physiol. 287

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310082
  • [Journal Article] Rapid double 8-nm steps by a kinesin mutant.2004

    • Author(s)
      Higuchi H
    • Journal Title

      EMBO J. 23

      Pages: 2993-9

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310082
  • [Journal Article] Rapid double 8-nm steps by a kinesin mutant2004

    • Author(s)
      Higuchi H, Bronner CE, Park HW and Endow SA
    • Journal Title

      EMBO J. 23

      Pages: 2993-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Rapid double 8-nm steps by a kinesin mutant.2004

    • Author(s)
      Higuchi H, Bronner CE, Park HW, Endow SA.
    • Journal Title

      EMBO J. 23

      Pages: 2993-2999

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310082
  • [Journal Article] Mechanochemical coupling of two substeps in a single myosin V motor.2004

    • Author(s)
      Uemura S, Higuchi H, Olivares AO, De La Cruz EM, Ishiwata S.
    • Journal Title

      Nat Struct Mol Biol. 11

      Pages: 877-883

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310082
  • [Journal Article] Rapid double 8-nm steps by a kinesin mutant2004

    • Author(s)
      Higuchi H
    • Journal Title

      EMBO J 23

      Pages: 2993-2999

    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Essential Residues, W177 and R198, of LukF for Phosphatidylcholine-Binding and Pore-Formation by Staphylococcal g-Hemolysin on Human Erythrocyte2004

    • Author(s)
      N.Monma, V.T.Nguyen, J.Kaneko, H.Higuchi, Y.Kamio
    • Journal Title

      J.Biochem 136

      Pages: 427-431

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15380054
  • [Journal Article] Regional rheological differences in locomoting neutrophils2004

    • Author(s)
      Yanai, M. J. P. Butler, T. Suzuki. H. Sasaki and H. Higuchi
    • Journal Title

      Am. J. Physiol. 287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Rapid double 8-nm steps by a kinesin mutant2004

    • Author(s)
      Higuchi H
    • Journal Title

      EMBO J

    • Data Source
      KAKENHI-PROJECT-16310082
  • [Journal Article] Mechanochemical coupling of two substeps in a single myosin V motor2004

    • Author(s)
      Uemura S, Higuchi H, Olivares AO, De La Cruz EM and Ishiwata S
    • Journal Title

      Nat Struct Mol Biol. 11

      Pages: 877-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Regional rheological differences in locomoting neutrophils2004

    • Author(s)
      Yanai, M.J.P. Butler, T. Suzuki. H. Sasaki, H. Higuchi
    • Journal Title

      Am. J. Physiol 287

      Pages: 603-611

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Essential Residues, W177 and R198, of LukF for Phosphatidylcholine-Binding and Pore-Formation by Staphylococcal {gamma}-Hemolysin on Human Erythrocyte Membranes2004

    • Author(s)
      Monma N, Nguyen V T, Kaneko J, Higuchi H and Kamio Y
    • Journal Title

      J Biochem (Tokyo) 136

      Pages: 427-431

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Journal Article] Mechanochemical coupling of two substeps in a single myosin V motor2004

    • Author(s)
      Uemura S, Higuchi H, Olivares AO, De La Cruz EM, *Ishiwata S
    • Journal Title

      Nat Struct Mol Biol 11

      Pages: 877-83

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Rapid double 8-nm steps by a kinesin mutant2004

    • Author(s)
      Higuchi H
    • Journal Title

      EMBO J

    • Data Source
      KAKENHI-PROJECT-16083101
  • [Journal Article] Essential residues, W177 and R198, of LukF for phosphatidylcholinebinding and pore-formation by Staphylococcal gamma-hemolysin on human erythrocyte membranes.2004

    • Author(s)
      N.Monma, V.T.Nguyen, J.Kaneko, H.Higuchi, Y.Kamio.
    • Journal Title

      J.Biochem. 136

      Pages: 427-431

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380054
  • [Journal Article] Single-molecule imaging of cooperative assembly of γ-hemolysin on erythrocyte membranes.2003

    • Author(s)
      V.T.Nguyen, Y.Kamio, H.Higuchi
    • Journal Title

      The EMBO Journal 22(19)

      Pages: 4968-4979

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15380054
  • [Journal Article] Single-molecule imaging of cooperative assembly of γ-hemolysin on erythrocyte membranes.2003

    • Author(s)
      V.T.Nguyen, Y.Kamio, H.Higuchi.
    • Journal Title

      The EMBO Journal 22(19)

      Pages: 4968-4979

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380054
  • [Patent] 共焦点顕微鏡画像システム2011

    • Inventor(s)
      :樋口秀男、下澤東吾
    • Industrial Property Rights Holder
      :樋口秀男、下澤東吾
    • Industrial Property Rights Type
      特許
    • Filing Date
      2011-05-31
    • Overseas
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Patent] 光学装置及び結像方法2006

    • Inventor(s)
      渡邉朋信, 樋口秀男
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男
    • Acquisition Date
      2006-04-17
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Patent] 光学装置及び結像方法2006

    • Inventor(s)
      渡邉朋信, 樋口秀男
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男
    • Acquisition Date
      2006-04-17
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Patent] がん細胞への選択的作用組成物および治療用レーザー照射装置2005

    • Inventor(s)
      渡邉朋信, 樋口秀男, 佐藤崇
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男
    • Acquisition Date
      2005-06-03
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Patent] 光学装置2005

    • Inventor(s)
      渡邉朋信, 樋口秀男, 佐藤崇
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男, 佐藤崇
    • Acquisition Date
      2005-11-22
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Patent] 位置解析方法及び位置解析装置2005

    • Inventor(s)
      渡邉朋信, 樋口秀男, 佐藤崇
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男
    • Acquisition Date
      2005-10-24
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Patent] 顕微鏡ステージ、および、焦点位置計測装置と共焦点顕微鏡システム2005

    • Inventor(s)
      渡邉朋信, 樋口秀男
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男
    • Acquisition Date
      2005-04-27
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Patent] 光学装置2005

    • Inventor(s)
      渡邉朋信, 樋口秀男, 佐藤崇
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男, 佐藤崇
    • Acquisition Date
      2005-11-22
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Patent] がん細胞への選択的作用組成物および治療用レーザー照射装置2005

    • Inventor(s)
      渡邉朋信, 樋口秀男
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男
    • Acquisition Date
      2005-06-03
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Patent] 顕微鏡ステージ、および、焦点位置計測装置と共焦点顕微鏡システム2005

    • Inventor(s)
      渡邉朋信, 樋口秀男, 佐藤崇
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男
    • Acquisition Date
      2005-04-27
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Patent] 位置解析方法及び位置解析装置2005

    • Inventor(s)
      渡邉朋信, 樋口秀男
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男
    • Acquisition Date
      2005-10-24
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Patent] 単粒子三次元位置追跡方法2004

    • Inventor(s)
      渡邉朋信, 樋口秀男
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男
    • Acquisition Date
      2004-10-18
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Patent] 単粒子三次元位置追跡方法2004

    • Inventor(s)
      渡邉朋信, 樋口秀男, 佐藤崇
    • Industrial Property Rights Holder
      渡邉朋信, 樋口秀男
    • Acquisition Date
      2004-10-18
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Quantitative evaluation of cell damages by motility of intercellular organelles.2022

    • Author(s)
      Hideaki Ota, M. Sakuma and H. Higuchi.
    • Organizer
      Symposium on Internatinal Nanomedicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K23844
  • [Presentation] Quantitative evaluation of the decrease in intracellular mobility of cells in which ATP synthesis is inhibited2022

    • Author(s)
      Hideaki Ota, Hideo Higuchi
    • Organizer
      第 60 回日本 生物物理学会
    • Data Source
      KAKENHI-PROJECT-23K23844
  • [Presentation] Understanding of robustness in cancer morphology in cold temperature2022

    • Author(s)
      Yuta Sekiguchi, Hideo Higuchi, Motoshi Kaya
    • Organizer
      第 60 回日本 生物物理学会
    • Data Source
      KAKENHI-PROJECT-23K23844
  • [Presentation] 細胞の元気さを測る2022

    • Author(s)
      樋口秀男 , 太田英暁
    • Organizer
      遺伝子・ デリバリー研究会 第 21 回シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K23844
  • [Presentation] An automatic detection and tracking method for the 3D reconstruction of vesicle movement in a living cell2022

    • Author(s)
      Seohyun Lee, Hyuno Kim, Hideo Higuchi.
    • Organizer
      第 60 回日本生物物理学会.
    • Data Source
      KAKENHI-PROJECT-23K23844
  • [Presentation] Relations between Motions of Intracellular Particles and Cell Death in Damaged Cells.2021

    • Author(s)
      Hideaki Ota, Hideo Higuchi.
    • Organizer
      The 59th Annual meeting of the biophyscical society of Japan.
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] Understanding of vesicle transport using machine learning and image processing technology.2021

    • Author(s)
      Seohyun Lee, Hyuno Kim, Masatoshi Ishikawa, Hideo Higuchi.
    • Organizer
      The 59th Annual meeting of the biophyscical society of Japan.
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] Unified Understanding of Active Motions Driven by Proteins2021

    • Author(s)
      Takakuni Fukumoto, Kazuo Sasaki, Hideo Higuchi.
    • Organizer
      The 59th Annual meeting of the biophyscical society of Japan.
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] 細胞損傷度の定量化に向けた細胞内ナノ粒子の動態解析2021

    • Author(s)
      太田英暁, 樋口秀男
    • Organizer
      ナノ学会
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] 損傷した細胞における損傷した 細胞における細胞内粘性の経時的測定2020

    • Author(s)
      太田英暁, 樋口秀男
    • Organizer
      日本物理学会 第76 回年次大会
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] 、Molecular properties of single cardiac myosin adapted for heart functions revealed by single- and multi-molecule approaches2020

    • Author(s)
      黄勇太, 鷲尾巧, 樋口秀男, 茅元司
    • Organizer
      第58 回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] Contraction Rhythm Homeostasis manifested in warmed cardiomyocytes2020

    • Author(s)
      Seine A Shintani, Takumi Washio, Hideo Higuchi
    • Organizer
      The 98th Annual Meeting of The Physiological Society of Japan.
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] 損傷した細胞における細胞内粘 性と生存確率の関係2020

    • Author(s)
      太田英暁, 樋口秀男
    • Organizer
      日本物理学会2020 秋季大会
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] Cytoplasmic Viscosity and Cellular Viability of the Damaged Cells2020

    • Author(s)
      太田英暁, 樋口秀男
    • Organizer
      第58 回日本 生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] Reverse stroke of cardiac myosin revealed by single molecule microscopy is essential for heart function2019

    • Author(s)
      黄 勇太, 鷲尾 巧, 樋口 秀男, 茅 元司
    • Organizer
      The 57th Annual Meeting of the Biophysical Society of Japan
    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Presentation] Measurement of force generation by dynein ensemble on a doublet microtubule obtained from sperm agella2019

    • Author(s)
      藤原貴史, 真行寺千佳子, 樋口秀男
    • Organizer
      第57 回日本生物物理学会年会、
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] Universal walk- ing model for processive motor proteins.2019

    • Author(s)
      Hideo Higuchi and Kazuo Sasaki
    • Organizer
      Joint Workshop between NanoLSI and Universal biology institute
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] Responses of cells to local heat- ing in cells using a nanoparticle2019

    • Author(s)
      太田英暁, 樋口秀男
    • Organizer
      第57 回日本生物物 理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] Reverse stroke of cardiac myosin revealed by single molecule microscopy is essential for heart function.2019

    • Author(s)
      Motoshi Kaya, Yongtae Hwang and Hideo Higuchi.
    • Organizer
      2nd Joint Symposium between mechanobaiology institute and Universal biology institute.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] Reverse stroke of cardiac myosin revealed by single molecule mi- croscopy is essential for heart function2019

    • Author(s)
      黄勇太, 鷲尾巧, 樋口秀男, 茅元司
    • Organizer
      第57 回日本 生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03189
  • [Presentation] 荷領域の測定から明らかになったキネシン1分子のステップ運動2018

    • Author(s)
      近藤雄一, 佐々木一夫, 樋口秀男
    • Organizer
      生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Three-dimensional vesicle motion in complex cytoskeletal network revealed by numerical analysis method2018

    • Author(s)
      Lee Seohyun , 樋口秀男
    • Organizer
      生物物理学
    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Presentation] 3D Nanoscale Tracking Data Analysis for Intracellular Organelle Movement using Machine Learning Approach.2018

    • Author(s)
      Seohyun Lee, Hyuno Kim, Masatoshi Ishikawa, and Hideo Higuchi
    • Organizer
      International conference on Artificial Intelligence in Information and Communication
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Three-dimensional vesicle motion in complex cytoskeletal network revealed by numerical analysis method2018

    • Author(s)
      Lee Seohyun , Hideo Higuchi
    • Organizer
      生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] 回折限界内に位置するミオシン複数分子の動態計測2018

    • Author(s)
      茅元司, 蘆田祐人, 上田正仁, 樋口秀男
    • Organizer
      生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Presentation] 広い負荷領域におけるキネシン1 分子のステップ運動2018

    • Author(s)
      近藤雄一, 佐々木一夫, 樋口秀男
    • Organizer
      ナノ学会
    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Presentation] Step sizes and rate constants of single-headedcytoplasmic dynein2018

    • Author(s)
      木下慶美, 神原丈敏, 西川香里, 茅元司, 樋口秀男
    • Organizer
      生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] 広い負荷領域におけるキネシン1 分子のステップ運動2018

    • Author(s)
      近藤雄一, 佐々木一夫, 樋口秀男
    • Organizer
      ナノ学会
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Behavior of polymerized microtubules interacted with dyneins still attached on a doublet microtubule detected by laser tweezers2018

    • Author(s)
      藤原貴史, 真行寺千佳子, 樋口秀男
    • Organizer
      生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] 光ピンセット技術を用いた心筋ミオシン集団の力学的性質2018

    • Author(s)
      黄勇太, 樋口秀男, 茅元司,
    • Organizer
      ナノ学会
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] 心機能に適した心筋ミオシンの集団的性質2018

    • Author(s)
      黄勇太, 樋口秀男, 茅元司
    • Organizer
      生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Molecular mechanism of self-oscillatory contraction of cardiac muscle2018

    • Author(s)
      S. Shintani, T. Washio, Y. Hwang, M, Kaya and H. Higuchi
    • Organizer
      International symposium on Nanomedicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Molecular mechanism of self-oscillatory contraction of cardiac muscle2018

    • Author(s)
      S. Shintani, T.Washio, Y. Hwang, M, Kaya and H.Higuchi
    • Organizer
      Internatinal symposium on Nanomedicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Presentation] Focus Stabilization by Axial Position Feedback in Biomedical Imaging Microscopy2018

    • Author(s)
      Seohyun Lee, Hyuno Kim, Hideo Higuchi
    • Organizer
      IEEE Sensors Applications Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Presentation] Trafficking of Endocytic Vesicles on Cytoskeleton in LiveCancer Cells. A3 Foresight 9th Meeting2017

    • Author(s)
      Seohyun Lee, Motoshi Kaya, Kohsuke Gonda, Hideo Higuchi.
    • Organizer
      A3 Foresight 9th Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Damage of cancer cells evaluated by intensity fluctuation of images under phase contrast microscope.2017

    • Author(s)
      Morihito. Sakuma, Yuichi. Kondo and Hideo. Higuchi
    • Organizer
      11th International Symposium on Nanomedicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] The step size and microtubule-binding time of single-headed dynein.2017

    • Author(s)
      Yoshimi Kinoshita , Taketoshi Kambara, Kaori Nishikawa, Motoshi Kaya, Hideo Higuchi.
    • Organizer
      The 55th Annual Meeting of the Biophysical Society of Japan(2017.9.19~9.21)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Step sizes and rate constants of single-headed dynein measured by optical tweezers2017

    • Author(s)
      Yoshimi Kinoshita, Hideo Higuchi.
    • Organizer
      International Workshop Dynein 2017,
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Quantitative evaluation of recovery from damage in cancer cells2017

    • Author(s)
      Morito Sakuma and Hideo Higuchi
    • Organizer
      Ito International Research Center
    • Place of Presentation
      東大(東京都文京区)
    • Year and Date
      2017-02-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Property of Cardiac Myosin Assemble Measured by Optical Trapping2017

    • Author(s)
      Yongtae Hwang, Hideo Higuchi.. Motoshi Kaya
    • Organizer
      A3 Foresight 9th Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Mechanical activity of dynein and its dynamical regulation underlying oscillatory movement of sperm flagella2017

    • Author(s)
      Chikako Shingyoji, Hiroshi Yoke,Yasuhide Izawa, Izumi Nakano,Yuichi Inoue, Hideo Higuchi
    • Organizer
      International Workshop Dynein 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] spontaneous oscillation of cardiac myosins2017

    • Author(s)
      Yongtae Hwang , Hideo Higuchi , Motoshi Kaya
    • Organizer
      The 55th Annual Meeting of the Biophysical Society of Japan
    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Presentation] Hideo Higuchi. Molecular Mechanism of Synchronous Force Generations among Myosin Molecules2017

    • Author(s)
      Motoshi Kaya, Takumi Washio, Hideo Higuchi
    • Organizer
      The 61st Annual Meeting of Biophysical Society
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2017-02-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] The power stroke distance of human cytoplasmic dynein2017

    • Author(s)
      Yoshimi Kinoshita, Taketoshi Kambara, Kaori Nishikawa, Motoshi Kaya, Hideo Higuchi
    • Organizer
      The 61st Annual Meeting of Biophysical Society
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2017-02-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Damage of cancer cells evaluated by intensity fluctuation of images under phase contrast microscope2017

    • Author(s)
      Morihito. Sakuma, Yuichi. Kondo and Hideo Higuchi
    • Organizer
      11th International Symposium on Nanomedicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Trafficking of Endocytic Vesicles on Cytoskeleton in LiveCancer Cells2017

    • Author(s)
      Seohyun Lee, Motoshi Kaya, Kohsuke Gonda, Hideo Higuchi
    • Organizer
      A3 Foresight 9th Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Presentation] Trafficking of endocytic vesicles in live cancer cells2017

    • Author(s)
      Seohyun Lee , Kohsuke Gonda , Motoshi Kaya , Hideo Higuchi
    • Organizer
      The 55th Annual Meeting of the Biophysical Society of Japan
    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Presentation] Property of Cardiac Myosin Assemble Measured by Optical Trapping2017

    • Author(s)
      Yongtae Hwang, Hideo Higuchi.. Motoshi Kaya
    • Organizer
      A3 Foresight 9th Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Presentation] Step sizes and rate constants of single-headed dynein measured by optical tweezers2017

    • Author(s)
      Yoshimi Kinoshita, Hideo Higuchi.
    • Organizer
      International Workshop Dynein 2017, International Conference Center, Awaji Yumebutai (2017.10.29~11.1)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Mechanical activity of dynein and its dynamical regulation underlying oscillatory movement of sperm flagella2017

    • Author(s)
      Chikako Shingyoji, Hiroshi Yoke,Yasuhide Izawa, Izumi Nakano,Yuichi Inoue, Hideo Higuchi.
    • Organizer
      International Workshop Dynein 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Understanding of cooperative force generation among skeletal myosins based on direct observation of individual myosin dynamics2017

    • Author(s)
      Motoshi Kaya , Hideo Higuchi
    • Organizer
      The 55th Annual Meeting of the Biophysical Society of Japan
    • Data Source
      KAKENHI-PROJECT-17K19343
  • [Presentation] Cooperative force generation by muscle myosin molecules interacting with actin filaments.2016

    • Author(s)
      Hideo Higuchi, Motoshi Kaya, Takumi Washio, Seine Shintani.
    • Organizer
      KIAS Protein Science Soul Korea
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04773
  • [Presentation] Mechanism of Synchronous Force Generations Between Skeletal Myosins in Myofilament2016

    • Author(s)
      Motoshi Kaya, Yoshiaki Tani, Takumi Washio, Toshiaki Hisada, Hideo Higuchi
    • Organizer
      The 19th European Bioenergetics Conference
    • Place of Presentation
      Riva del Garda, Italy
    • Year and Date
      2016-07-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Cooperative force generation by muscle myosin molecules interacting with actin filaments2016

    • Author(s)
      Hideo Higuchi
    • Organizer
      International Symposium on Universal Biology Univ. Tokyo
    • Place of Presentation
      東大(東京都文京区)
    • Year and Date
      2016-11-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Cooperative force generation by muscle myosin molecules interacting with actin filaments2016

    • Author(s)
      Hideo Higuchi, Motoshi Kaya, Takumi Washio, Seine Shintani
    • Organizer
      KIAS Protein Science
    • Place of Presentation
      Soul, Korea
    • Year and Date
      2016-09-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] ミオシン集団の持つ協同性と周期性2016

    • Author(s)
      樋口秀男, 茅元司, 鷲尾巧, 新谷正嶺
    • Organizer
      生物物理学会東北支部会
    • Place of Presentation
      東北大 (宮城県仙台市)
    • Invited
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Intermolecular cooperativity of skeletal myosins enhances force output in myofilaments2015

    • Author(s)
      Motoshi Kaya, Yoshiaki Tani, Takumi Washi, Toshiaki Hisada and Hideo Higuchi
    • Organizer
      The 59th Annual Meeting of the Biophysical Society
    • Place of Presentation
      Convention Center(Baltimore、USA)
    • Year and Date
      2015-02-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Novel mouse xenograft model for noninvasive in vivo imaging of human tumor cell and tissue in the auricle.2015

    • Author(s)
      喜多清、樋口秀男
    • Organizer
      第120回日本解剖学会
    • Place of Presentation
      神戸国際会議場 (兵庫県 神戸市)
    • Year and Date
      2015-03-21
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] 蛍光量子ドットを用いた細胞内高速小胞輸送機構の解明2014

    • Author(s)
      菊島健児、樋口秀男
    • Organizer
      生物物理学会大会
    • Place of Presentation
      コンベンションセンター(北海道 札幌市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Novel mouse xenograft model for noninvasive in vivo imaging of human tumor cell and tissue in the auricle.2014

    • Author(s)
      Sayaka Kita and Hideo Higuchi
    • Organizer
      The American Society for Cell Biology
    • Place of Presentation
      Convention Center (Philadelphia, USA)
    • Year and Date
      2014-12-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] 量子ドットを用いた脳がん幹細胞表面の膜たんぱく質の運動解析2014

    • Author(s)
      佐久間守仁、喜多清、樋口秀男
    • Organizer
      生物物理学会大会
    • Place of Presentation
      生物物理学会大会
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] 蛍光量子ドットを用いた細胞内高速小胞輸送機構解明2014

    • Author(s)
      菊島健児、樋口秀男
    • Organizer
      ナノ学会大会
    • Place of Presentation
      おお ばくプラザ(京都府 宇治市)
    • Year and Date
      2014-05-22
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Noninvasive in vivo imaging of neutrophil and tumor in mouse auricles2014

    • Author(s)
      Hideo Higuchi, Kenji Kikushima and Sayaka Kita
    • Organizer
      8th Internal Symposium on Nanomedicine
    • Place of Presentation
      愛媛大学(愛媛県 松山市)
    • Year and Date
      2014-12-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Imaging of Porphyromonaus ginigivalis infection using quantum dot2014

    • Author(s)
      菊島健児、中尾龍馬、樋口秀男
    • Organizer
      日本免疫学会
    • Place of Presentation
      国立京都国際会館 (京都府 京都市)
    • Year and Date
      2014-12-10
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Noninvasive in vivo imaging of neutrophil and tumor in mouse auricles2014

    • Author(s)
      Hideo Higuchi, Kenji Kikushima and Sayaka Kita
    • Organizer
      A3 Foresight Symposium on Nanomedicine
    • Place of Presentation
      大観荘(宮城県 松島市)
    • Year and Date
      2014-09-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] マウス内単一分子イメージング2013

    • Author(s)
      樋口秀男
    • Organizer
      国立感染症研究所学友会セミナー
    • Place of Presentation
      東京 国立感染症研究所
    • Year and Date
      2013-04-17
    • Invited
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Noninvasive in vivo imaging of neutrophil and tumor in mouse auricles2013

    • Author(s)
      樋口秀男,菊島健児, 喜多清
    • Organizer
      Dynein 2013 International Workshop
    • Place of Presentation
      オルビスホール(兵庫)
    • Invited
    • Data Source
      KAKENHI-PROJECT-25650047
  • [Presentation] 光の運動量変化に基づく細胞内 小胞に働く力の測定」2013

    • Author(s)
      三上貴司、樋口秀男
    • Organizer
      2013 年生体運動研究合同班会議
    • Place of Presentation
      広島大学(広島県)
    • Data Source
      KAKENHI-PROJECT-23247022
  • [Presentation] non-invasive technique for the in vivo tracking of high-speed vesicle transport in mouse neutrophils2013

    • Author(s)
      菊島健児, 喜多清, 樋口秀男
    • Organizer
      第51回日本生物物理学会年会
    • Place of Presentation
      国立京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-25650047
  • [Presentation] Noninvasive in vivo imaging of Tumor cells in mouse Auricles.2013

    • Author(s)
      喜多清、菊島健児、樋口秀男
    • Organizer
      The 4th Taiwan-Japan Symposium on Nanomedicine
    • Place of Presentation
      Academia Sinca(Taipei)
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] The mechanomhemical cycle of human cytoplasmic dynein under external force.2013

    • Author(s)
      神原丈敏、谷芳明、茅元司、島知弘、樋口秀男
    • Organizer
      14th International Alpbach Workshop on Molecular Motors
    • Place of Presentation
      Albach (Austria)
    • Data Source
      KAKENHI-PROJECT-23247022
  • [Presentation] 外部 負荷存在下でのヒト細胞質ダイニンのメカノケミカル サイクル2012

    • Author(s)
      神原丈敏、谷芳明、茅元司、島知弘、樋口秀男
    • Organizer
      第50回日本生物物理学会年会
    • Place of Presentation
      名古屋大学(愛知県)
    • Data Source
      KAKENHI-PROJECT-23247022
  • [Presentation] Single molecule biophysics in an in vivo and in vitro2012

    • Author(s)
      Higuchi H.
    • Organizer
      Japan-Taiwan joint symposium
    • Place of Presentation
      京都大学(京都府)
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] In vivo imaging of single molecules in cancer cells of xenograft model under noninvasive condition2012

    • Author(s)
      喜多清、菊島健児、樋口秀男
    • Organizer
      第71 回日本癌学会学術総会
    • Place of Presentation
      札幌教育文化会館(北海道)
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] マウス骨格筋in vivo イメージングによるサルコメア構造と微小管系の可 視化2012

    • Author(s)
      小林琢也、茅元司、樋口秀男
    • Organizer
      ナノ学会第10 回大会
    • Place of Presentation
      大阪大学(大阪府)
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Non-invasive in vivo imaging of vesicle movement in neutrophils in mouse ear2012

    • Author(s)
      菊島健児、喜多清、樋口秀男
    • Organizer
      第50 回日本生物物理学会年会
    • Place of Presentation
      名古屋大学(愛知県)
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] 量子ドットを用いたマ ウス耳内における白血球内小胞運動の非侵襲イメージ ング2012

    • Author(s)
      菊島健児、喜多清、樋口秀男
    • Organizer
      ナノ学会第10 回大会
    • Place of Presentation
      大阪大学(大阪府)
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Non-invasive in vivo imaging of vesicle movements of neutrophil in the mouse ear using quantum dots2012

    • Author(s)
      菊島健児、喜多清、樋口秀男
    • Organizer
      34th Naito conference
    • Place of Presentation
      シャトーレガトーキングダムサッポロ(北海道)
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Single molecule biophysics in an in vivo and in vitro2012

    • Author(s)
      Higuchi H.
    • Organizer
      Japan-Taiwan joint symposium
    • Place of Presentation
      京都大学(京都府)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23247022
  • [Presentation] Steps, Force and Motile Mechanism of Cytoplasmic Dynein2009

    • Author(s)
      Hideo Higuchi
    • Organizer
      Biophysical Society's 53^<rd> Annual Meeting
    • Place of Presentation
      ボストン、アメリカ
    • Year and Date
      2009-03-02
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Steps, Force and Motile Mechanism of Cytoplasmic Dynein2009

    • Author(s)
      Hideo Higuchi
    • Organizer
      Biophysical Society's 53rd Annual Meeting
    • Place of Presentation
      ボストン、アメリカ
    • Year and Date
      2009-03-02
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Motility of single molecules of dynein, kinesin, and myosin in vitro and in cells2009

    • Author(s)
      Higuchi, H
    • Organizer
      Symposium on the MESO CONTROL of the cells, by the cells, for the cells.
    • Place of Presentation
      Kyoto, Japan.
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Cargo Transport by Single Molecular Motors2009

    • Author(s)
      Higuchi, H.
    • Organizer
      The Biophysical Society's 53rd Annual Meeting
    • Place of Presentation
      Boston, USA.
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Motility of single molecules of dynein, kinesin, and myosin in vitro and in cells2009

    • Author(s)
      Higuchi H.
    • Organizer
      Symposium on the MESO CONTROL of the cells, by the cells, for the cells
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Cargo Transport by Single Molecular Motors2009

    • Author(s)
      Higuchi H.
    • Organizer
      The Biophysical Society's 53rd An-nual Meeting
    • Place of Presentation
      Boston, USA.
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Step size and force generated by motor protein dynein2008

    • Author(s)
      Higuchi H.
    • Organizer
      236th National Meeting & Exposition of the American Chemical Society
    • Place of Presentation
      Philadelphia, USA.
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Imaging of stepwise motility of single motor molecules in living cells2008

    • Author(s)
      Higuchi, H
    • Organizer
      39th NIPS International Symposium & 7th OIB Symposium
    • Place of Presentation
      Okazaki, Japan
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Molecular mechanism of dynein motility in vitro and cells2008

    • Author(s)
      Higuchi, H.
    • Organizer
      The 46th Annual Meeting of the Biophysical Society of Japan
    • Place of Presentation
      Fukuoka, Japan.
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Single molecule imaging of motor proteins in vitro and in vivo2008

    • Author(s)
      Higuchi H.
    • Organizer
      Bio-Soft Matter Workshop
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Single molecule imaging of motor proteins in vitro and in vivo2008

    • Author(s)
      Higuchi, H
    • Organizer
      Bio-Soft Matter Workshop
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Myosin, kinesin and dynein in vitro and cells2008

    • Author(s)
      Higuchi, H.
    • Organizer
      nd International Symposium on Bio-nanosystems
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Step size of dynein is determined by distances of a power stroke and fluctuation2008

    • Author(s)
      Higuchi H.
    • Organizer
      Gordon Reserch Conferences
    • Place of Presentation
      New Hampshire, USA.
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] 組換・天然・細胞内ダイニンの分子運動2008

    • Author(s)
      樋口秀男
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Step size of dynein is determined by distances of a power stroke and fluctuation2008

    • Author(s)
      Higuchi, H
    • Organizer
      Gordon Reserch Conferences
    • Place of Presentation
      New Hampshire, USA
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Molecular mechanism of dynein motility in vitro and cells2008

    • Author(s)
      Higuchi H.
    • Organizer
      The 46th Annual Meeting of the Biophysical Society of Japan
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Step size and force generated by motor protein dynein2008

    • Author(s)
      Higuchi, H
    • Organizer
      236th National Meeting & Exposition of the American Chemical Society
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] 組換・天然・細胞内ダイニンの分子運動2008

    • Author(s)
      樋口秀男
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Myosin, kinesin and dynein in vitro and cells2008

    • Author(s)
      Higuchi H.
    • Organizer
      2nd International Symposium on Bio-nanosystems
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Imaging of stepwise motility of single motor molecules in living cells2008

    • Author(s)
      Higuchi H.
    • Organizer
      39th NIPS International Symposium & 7th OIB Symposium
    • Place of Presentation
      Okazaki, Japan
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Coordination of two single-headed cytoplasmic dyneins creates processive move-ment2006

    • Author(s)
      Higuchi, H.
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      New Hampshire, USA
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Single molecule imaging of motor proteins in living cells2006

    • Author(s)
      Higuchi H. and T. M. Watanabe
    • Organizer
      The 7th international conference on systems Biology
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Step size and force generated by axonemal and cytoplasmic dynein2006

    • Author(s)
      Higuchi, H
    • Organizer
      Biophysical society Discussion meeting
    • Place of Presentation
      Alisoma, USA
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Coordination of two single-headed cytoplasmic dyneins creates processive move-ment2006

    • Author(s)
      Higuchi H.
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      New Hampshire, USA.
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Step size and force generated by axonemal and cytoplasmic dynein2006

    • Author(s)
      Higuchi H.
    • Organizer
      Biophysical society Discussion meeting
    • Place of Presentation
      Alisoma, USA.
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Introduction to the motor proteins2006

    • Author(s)
      Higuchi, H.
    • Organizer
      International symposium on Bio-nanosystems
    • Place of Presentation
      Mastushima, Japan
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Introduction to the motor proteins2006

    • Author(s)
      Higuchi H.
    • Organizer
      International symposium on Bio-nanosystems
    • Place of Presentation
      Mastushima, Japan
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Single molecule imaging of motor proteins in living cells2006

    • Author(s)
      Higuchi, H., T.M. Watanabe
    • Organizer
      The 7th international conference on systems Biology
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Nano-biology and nano-medicine on can-cer cells2005

    • Author(s)
      Higuchi H., T. M. Watanabe, H. Tada and N. Ohuchi
    • Organizer
      Nano-Science and Technology for Medical Applications
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Nano-biology and nano-medicine on can-cer cells2005

    • Author(s)
      Higuchi, H., T.M. Watanabe, H. Tada, N. Ohuchi
    • Organizer
      Nano-Science and Technology for Medical Applications.
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Nano-biology and nano-medicine on can-cer cells2005

    • Author(s)
      Higuchi, H., T.M. Watanabe, H. Tada, N. Ohuchi
    • Organizer
      Nano-Science and Technology for Medical Applications
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Biased Binding, Processive Steps and Oscillatory Movement of Single-headed Kinesin2004

    • Author(s)
      Higuchi H.
    • Organizer
      Structural Insights into Kinesin Function
    • Place of Presentation
      Washington, USA.
    • Data Source
      KAKENHI-PROJECT-16083201
  • [Presentation] Biased Binding, Processive Steps and Oscillatory Movement of Single-headed Kinesin2004

    • Author(s)
      Higuchi, H
    • Organizer
      Structural Insights into Kinesin Function
    • Place of Presentation
      Washington, USA
    • Data Source
      KAKENHI-PROJECT-16083101
  • [Presentation] Noninvasive in vivo imaging of neutrophil and tumor in mouse auricles

    • Author(s)
      Hideo Higuchi, Kenji Kikushima and Sayaka Kita
    • Organizer
      8th Internal Symposium on Nanomedicine
    • Place of Presentation
      愛媛県 松山市
    • Year and Date
      2014-12-07 – 2014-12-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-25650047
  • [Presentation] Symposium on Biophysics toward In Vivo work

    • Author(s)
      7.Hideo Higuchi and Norio Fukuda
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2013-10-28 – 2013-10-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-23247022
  • [Presentation] A non-invasive technique for the in vivo tracking of high-speed vesicle transport in mouse neutrophils

    • Author(s)
      菊島健児、喜多清、樋口秀男
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2013-10-28 – 2013-10-30
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Biophysical and Biochemical characterization of human cytoplasmic dynein.

    • Author(s)
      神原丈敏、木下慶美、中山貴之、樋口秀男
    • Organizer
      日本生物物理学会年会,
    • Place of Presentation
      京都
    • Year and Date
      2013-10-28 – 2013-10-30
    • Data Source
      KAKENHI-PROJECT-23247022
  • [Presentation] 量子ドットを用いたマウス耳内に おける白血球内小胞運動の非侵襲イメージング

    • Author(s)
      喜多清, 樋口秀男
    • Organizer
      ナノ学会
    • Place of Presentation
      東京
    • Year and Date
      2013-06-06 – 2013-06-08
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Noninvasive in vivo imaging of neutrophil and tumor in mouse auricles

    • Author(s)
      Hideo Higuchi, Kenji Kikushima and Sayaka Kita
    • Organizer
      The International Symposium on Multi-Scale Muscle Mechanics
    • Place of Presentation
      北九州
    • Year and Date
      2013-11-07 – 2013-11-10
    • Invited
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Symposium on Biophysics toward In Vivo work

    • Author(s)
      Hideo Higuchi and Norio Fukuda
    • Organizer
      日本生物物理学会
    • Place of Presentation
      京都
    • Year and Date
      2013-10-28 – 2013-10-30
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] Power Stroke Measurement of Human Cytoplasmic Dynein

    • Author(s)
      木下慶美、神原丈敏、池田諭史、樋口秀男
    • Organizer
      日本生物物理学会年会,
    • Place of Presentation
      京都
    • Year and Date
      2013-10-28 – 2013-10-30
    • Data Source
      KAKENHI-PROJECT-23247022
  • [Presentation] Molecular properties and dynamics of single skeletal myosins designed for force generations in ensemble of myosin molecules

    • Author(s)
      茅元司、樋口秀男
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2013-10-28 – 2013-10-30
    • Data Source
      KAKENHI-PLANNED-23107002
  • [Presentation] 蛍光量子ドットを用いた細胞内高速小胞輸送機構の解明

    • Author(s)
      菊島健児、樋口秀男
    • Organizer
      日本生物物理学会年会,
    • Place of Presentation
      北海道 札幌市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25650047
  • [Presentation] 蛍光量子ドットを用いた細胞内高速小胞輸送機構の解明

    • Author(s)
      菊島健児、樋口秀男
    • Organizer
      ナノ学会
    • Place of Presentation
      京都府 京都
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-25650047
  • [Presentation] Imaging of Porphyromonas gingivalis infection using quantum dots

    • Author(s)
      菊島健児、中尾龍馬、樋口秀男
    • Organizer
      第43回日本免疫学会
    • Place of Presentation
      京都
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-26462866
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    # of Collaborated Products: 1 results
  • 2.  KOBIRUMAKI Fuyu (40548905)
    # of Collaborated Projects: 3 results
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