MATSUI Hiroaki 松井宏晃

… Alternative Names

MATUI Hiroaki 松井宏晃

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Researcher Number	90181685
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2014: 聖マリアンナ医科大学, 医学部, 教授 2012 – 2013: 聖マリアンナ医科大学, 医学(系)研究科(研究院), 教授 2010: 聖マリアンナ医科大学, 医学(系)研究科(研究院), 教授 1998 – 2008: 聖マリアンナ医科大学, 医学部, 教授 1995 – 1997: 聖マリアンナ医科大学, 医学部, 講師 1989 – 1991: 聖マリアンナ医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Psychiatric science / Psychiatric science Except Principal Investigator Psychiatric science / Psychiatric science
Keywords	Principal Investigator 選択的スプライシング / ラット縫線核由来RN46A細胞 / 神経特異的抑制因子 / 抗うつ薬 / NF-Y / AP-2 / CREB / D_3ドーパミン(DA)受容体 / ヒト神経芽細胞腫SY-5Y細胞 / 逆転写・ポリメラーゼ連鎖(RT-PCR)反応 … More / long PCR法 / アルツハイマー病 / βアミロイド蛋白質前駆体遺伝子 / エクソンスキッピング / エクソンスプライシング促進配列 / エクソンスプライシング抑制配列 / モルフォリノオリゴヌクレオチド / 2'-0-Met RNA / セロトニン神経系 / クロマチン免疫沈降法 / セロトニン神経細胞特異的転写因子Pet-1 / Pet-1標的遺伝子 / 転写因子 / 遺伝子発現 / クロマチン沈降法 / β_1 ^-アドレナリン受容体 / 受容体調節機構 / 受容体遺伝子発現 / βーアドレナリン受容体 / 受容体遺伝子発現調節 / 抗うつ薬作用機序 / βアドレナリン受容体 / 受容体遺伝子発現調節機構 / beta_1-adrenergic receptor / antidepressant / receptor regulation / receptor gene expression / 5-HT_4受容体 / 5-HT_4受容体遺伝子 / セロトニン受容体 / セロトニン4S受容体 / セロトニン4L受容体 / アデニル酸シクラーゼ / β_1アドレナリン受容体遺伝子 / グルココルチコイド受容体 / 転写抑制 / β1アドレナリン受容体遺伝子 / デキサメサゾン / β1-adrenergic receptor / Glucocorticoid receptor / Transcriptional repression / Antidepressant / トリプトファン水酸化酵素2 / トリプトファン水酸化酵素1 / 転写制御領域 / 神経特異的抑制配列 / ヒストンデアセチラーゼ / ヒト肺小細胞癌HSP-77細胞 / ヒト神経芽細胞腫SH-SY5Y細胞 / セロトニン神経特異的転写因子 / ヒト脳型トリプトファン水酸化酵素 / ヒト抹消型トリプトファン水酸化酵素 / ラット縫線由来RN46A細胞 / セロトニン系神経細胞特異的転写因子 / Tryptophan hydroxylase 2 / Tryptophan hydroxylase 1 / Transcriptional regulation region / Rat serotonergic cell line RN46A / Neuron-restrictive silencer factor / Neuron-restrictive silencer element / Histone deacetylase … More Except Principal Investigator bHLH / GAP-43 / SNRI / E-box / eEF2 / 気分安定薬 / リチウム / 転写因子 / Math / Lithium / MATH / Transcription Factor / SSRI / NBD-F / dynamin / GTPase / ゲルシフトアッセイ / BHLH / Mod stabilizer / プロテオミクス / リン酸化 / MATH-2 / 転写因 / Mood stabilizer / Proteomics / Phosphorylation / ミルナシプラン / 薬物結合蛋白質 / milnacipran / binding protein / 時計遺伝子 / サーカディアンリズム Less

The identification of biomarker for the circadian rhythm of clock gene of the bipolar disorder
- Principal Investigator
  
  Haga Toshiaki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  St. Marianna University School of Medicine
Comprehensive identification of the Pet-1-target genes by chromatin immunoprecipitation assays in RN46A cells derived from the rat raphe nucleus.Principal Investigator
- Principal Investigator
  
  MATSUI Hiroaki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  St. Marianna University School of Medicine
The investigation to Dynamin-1 for new antidepressats binding protein
- Principal Investigator
  
  OSADA Kenichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  St.Marianna University School of Medicine
アルツハイマー病新規治療戦略:前駆体遺伝子エクソン17破断によるAβ生成抑制機構Principal Investigator
- Principal Investigator
  
  松井宏晃
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  St.Marianna University School of Medicine
The cloning and investigations for antidepressants affected protein with new chemical proteomics approach
- Principal Investigator
  
  OSADA Kenichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  St.Marianna University School of Medicine
Investigation for MATH-2 overexpressed transgenic mice to mood disorders model mice
- Principal Investigator
  
  OSADA Kenichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  St.Marianna University School of Medicine
Structural, functional and pormorphic analysis of the regulatory regions necessary for the expression of the human neuronal tryptophan hydroxylase gene.Principal Investigator
- Principal Investigator
  
  MATSUI Hiroaki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  St. Marianna University School of Medicine
Investigation for matching bHLH overexpressed transgenic mice to mood disorders model mice
- Principal Investigator
  
  OSAKA Kenichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  St Marianna University School of Medicine
The transcriptional regulation of the human β1-adrenergic receptor gene by stress-related transcription moleculesPrincipal Investigator
- Principal Investigator
  
  MATSUI Hiroaki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  St. Marianna University School of Medicine
アデニル酸シクラーゼ促進性ヒト5-HT4受容体の遺伝子構造ならびに機能調節機構Principal Investigator
- Principal Investigator
  
  松井宏晃
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  St. Marianna University School of Medicine
ヒトD_3ドーパミン受容体アイソフォームの発現調節および細胞内情報伝達機構Principal Investigator
- Principal Investigator
  
  松井宏晃
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  St. Marianna University School of Medicine
Structural Organization and Transcriptional Regulation of the Human beta_1-Adrenergic Receptor GenePrincipal Investigator
- Principal Investigator
  
  MATSUI Hiroaki
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Psychiatric science
- Research Institution
  ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE

All 2013 2012 2010 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] Tryptophan hydroxylase 2 (TPH2) in a neuronal cell line: modulation by cell differentiation and NRSF/rest activity.2012
- Author(s)
  Gentile MT, Nawa Y, Lunardi G, Florio T, Matsui H, Colucci-D'Amato L
- Journal Title
  
  J. Neurochemistry
  
  Volume: Vol. 123、No.6 Pages: 963-970
- DOI
  10.1111/jnc.12004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659548
[Journal Article] The Proteome Analysis to the rat brain protein after long-term lithium2006
- Author(s)
  M. Nakano, K. Osada, A. Misonoo, K. Takahashi, M. Takahashi, Y. Ogawa, S. Kanai, D. Tanaka, T. Hishinuma, Y. Sasuga, H. Nishikawa, H, Matsui, M. Yamada, M. Asakura
- Journal Title
  
  Neurochemistry 45
  
  Pages: 544-544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591313
[Presentation] Transcriptional regulation of the human serotonin type 4(5-ht4) receptor gene:identification and characterization of novel promoter and enhancer2013
- Author(s)
  Yukino Nawa, Masanori Ootaki, Rie Kuwabara, Tomoko Hiroi, Ryoya Takahashi, Hiroaki Matsui
- Organizer
  北米神経科学会
- Place of Presentation
  サンディエゴ（米国）
- Data Source
  KAKENHI-PROJECT-24659548
[Presentation] ヒトセロトニン4受容体遺伝子発現調節機構：ERG、EGRおよびNF1による調節2013
- Author(s)
  那和雪乃、大滝正則、桑原理恵、廣井朋子、高橋良哉、松井宏晃
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Data Source
  KAKENHI-PROJECT-24659548
[Presentation] Fluvoxamine and Sigma-1 Receptor Agonists Dehydroepiandrosterone (DHEA)-sulfate Induces the Ser473-phosphorylation of Akt-1 in PC12 Cells.2010
- Author(s)
  Osada K, Haga T, Ogawa Y, Matsui H, Nakano M, Asakura M, Yamaguchi N
- Organizer
  41th Annual Meeting of Neuroscience
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-20591380
[Presentation] Chronic trifluoperazine treatment increased P-glycoprotein in the rat brain.2009
- Author(s)
  Osada K, Ogawa Y, Matsui H, Haga T, Nakano M, Takahashi K, Fujiwara K, Yanagida T, Kanai S
- Organizer
  40th Annual Meeting of Neuroscience
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20591380
[Presentation] Regulation of the human tryptophan hydroxylase-2 gene promoter activity in immortalized serotonergic RN46A cells.2008
- Author(s)
  Hiroaki Matsui
- Organizer
  Serotonin Club Satellite Meeting(the EPHAR 2008Congress Satellite Meeting)
- Place of Presentation
  オックスフォード、英国
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-19659294
[Presentation] Regulation of the human tryptophan hydroxylase-2 gene promoter activity in immortalized serotonergic RN46A cells2007
- Author(s)
  Hiroaki Matsui
- Organizer
  37th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  米国、San Diego
- Data Source
  KAKENHI-PROJECT-19659294

1. OSADA Kenichi (20233504)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
2. ASAKURA Mikio (70103504)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
3. HIROI Tomoko (20238398)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. INO Miyuki (20203218)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YAMADA Mituhiko (60240040)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. KIDA Satoshi (80301547)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KATOU Tomohiro (80233807)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SASUGA Yasuo (60308450)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MIYOSHI Hiroshi (80322519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MISONOO Atushi (20410128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. GAWA Yuriko (90449398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. TANAKA Daisuke (80410124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NAWA Yukino (10549786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. KANEKO Rituko (00161183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Haga Toshiaki (80535625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 長谷川浩 (80288183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 中野三穂 (90621574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MATSUI Hiroaki 松井 宏晃

MATUI Hiroaki 松井 宏晃

Research Projects

Research Products

Co-Researchers

The identification of biomarker for the circadian rhythm of clock gene of the bipolar disorder

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive identification of the Pet-1-target genes by chromatin immunoprecipitation assays in RN46A cells derived from the rat raphe nucleus.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The investigation to Dynamin-1 for new antidepressats binding protein

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アルツハイマー病新規治療戦略:前駆体遺伝子エクソン17破断によるAβ生成抑制機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The cloning and investigations for antidepressants affected protein with new chemical proteomics approach

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation for MATH-2 overexpressed transgenic mice to mood disorders model mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural, functional and pormorphic analysis of the regulatory regions necessary for the expression of the human neuronal tryptophan hydroxylase gene.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation for matching bHLH overexpressed transgenic mice to mood disorders model mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The transcriptional regulation of the human β1-adrenergic receptor gene by stress-related transcription moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アデニル酸シクラーゼ促進性ヒト5-HT4受容体の遺伝子構造ならびに機能調節機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒトD_3ドーパミン受容体アイソフォームの発現調節および細胞内情報伝達機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural Organization and Transcriptional Regulation of the Human beta_1-Adrenergic Receptor GenePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Tryptophan hydroxylase 2 (TPH2) in a neuronal cell line: modulation by cell differentiation and NRSF/rest activity.2012

Author(s)

Journal Title

MATSUI Hiroaki 松井宏晃

MATUI Hiroaki 松井宏晃