ASAKURA Mikio 朝倉幹雄

… Alternative Names

朝倉幹雄アサクラミキオ

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Researcher Number	70103504
External Links
Affiliation (Current)	2022: 聖マリアンナ医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2015: 聖マリアンナ医科大学, 医学部, 教授 2010: 聖マリアンナ医科大学, 医学部, 准教授 2007 – 2008: St.Marianna University School of Medicine, 医学部, 准教授 2000 – 2006: 聖マリアンナ医科大学, 医学部, 助教授 1988 – 1990: 聖マリアンナ医科大学, 医学部, 助教授 … More 1988: St. Marianna University School of Medicine, Associate Professor, 医学部, 教授 1987: 聖マリアンナ医科大学, 講師 1986: 聖マ医大, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Psychiatric science / Psychiatric science Except Principal Investigator Psychiatric science / Psychiatric science
Keywords	Principal Investigator Serotonin / SNRI / ミルナシプラン / 二次元電気永動 / 質量分析 / サートラリン / フルボキサミン / スルピリド / 抗うつ薬 / β受容体ダウンレギュレーション … More / セロトニン / イノシトールリン脂質代謝回転 / ブロテインキナーゼC / Phorbol-12 / 13-dibutyrate(IPDBu) / β-レセプターdown-regulation / プロテインキナーゼC / イシノトールリン脂質代謝 / Phorbol-12、13-dibutyrate (PDBu) / 非定型抗うつ薬 / イノシトーリルン脂質 / β受容体リン酸化反応 / β受容体 / GTP結合調節蛋白質 / アデニル酸シクラーゼ / ホルボールジエステル / イノシトールリン脂質 / Antidepressants / -Receptor down-regulation / Protein Kinase C / Inositol-phospholipid turnover … More Except Principal Investigator bHLH / GAP-43 / 抗うつ薬 / E-box / eEF2 / NF-Y / AP-2 / CREB / 気分安定薬 / リチウム / 転写因子 / Math / Lithium / MATH / Transcription Factor / SNRI / dynamin / GTPase / β_1 ^-アドレナリン受容体 / 受容体調節機構 / 受容体遺伝子発現 / βーアドレナリン受容体 / 受容体遺伝子発現調節 / 抗うつ薬作用機序 / βアドレナリン受容体 / 受容体遺伝子発現調節機構 / beta_1-adrenergic receptor / antidepressant / receptor regulation / receptor gene expression / β_1アドレナリン受容体遺伝子 / グルココルチコイド受容体 / 転写抑制 / β1アドレナリン受容体遺伝子 / デキサメサゾン / β1-adrenergic receptor / Glucocorticoid receptor / Transcriptional repression / Antidepressant / ゲルシフトアッセイ / BHLH / Mod stabilizer / プロテオミクス / リン酸化 / MATH-2 / 転写因 / Mood stabilizer / Proteomics / Phosphorylation / トリプトファン水酸化酵素2 / トリプトファン水酸化酵素1 / 転写制御領域 / ラット縫線核由来RN46A細胞 / 神経特異的抑制因子 / 神経特異的抑制配列 / ヒストンデアセチラーゼ / ヒト肺小細胞癌HSP-77細胞 / ヒト神経芽細胞腫SH-SY5Y細胞 / セロトニン神経特異的転写因子 / ヒト脳型トリプトファン水酸化酵素 / ヒト抹消型トリプトファン水酸化酵素 / ラット縫線由来RN46A細胞 / セロトニン系神経細胞特異的転写因子 / Tryptophan hydroxylase 2 / Tryptophan hydroxylase 1 / Transcriptional regulation region / Rat serotonergic cell line RN46A / Neuron-restrictive silencer factor / Neuron-restrictive silencer element / Histone deacetylase / 感情障害 / シグナル伝達 / 神経伝達 / セロトニン / カテコ-ルアミン / セカンド・メッセンジャ- / ジグナル伝達 / GTP結合 / イノシト-ルリン脂質代謝 / セロトニン受容体 / β受容体 / GABA受容体 / イミプラミン結合 / 細胞内情報伝達 / 神経伝達機構 / 細胞内情報伝達系 / アドレナリン受容体 / アミノ酸受容体 / Affective Disorders / Antidepressants / Signal Transduction / Neural Transmission / Serotonin / Catecholamine / Second Messenger / サーカディアンリズム Less

双極性障害に対する時計遺伝子バイオロジカルマーカーの探索
- Principal Investigator
  
  貴家康男
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  St. Marianna University School of Medicine
The investigation to Dynamin-1 for new antidepressats binding protein
- Principal Investigator
  
  OSADA Kenichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  St.Marianna University School of Medicine
新規抗うつ薬結合蛋白質過剰発現マウスのストレス耐性とうつ病モデル動物の検討Principal Investigator
- Principal Investigator
  
  朝倉幹雄
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  St.Marianna University School of Medicine
Investigation for MATH-2 overexpressed transgenic mice to mood disorders model mice
- Principal Investigator
  
  OSADA Kenichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  St.Marianna University School of Medicine
Structural, functional and pormorphic analysis of the regulatory regions necessary for the expression of the human neuronal tryptophan hydroxylase gene.
- Principal Investigator
  
  MATSUI Hiroaki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  St. Marianna University School of Medicine
Investigation for matching bHLH overexpressed transgenic mice to mood disorders model mice
- Principal Investigator
  
  OSAKA Kenichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  St Marianna University School of Medicine
The transcriptional regulation of the human β1-adrenergic receptor gene by stress-related transcription molecules
- Principal Investigator
  
  MATSUI Hiroaki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  St. Marianna University School of Medicine
Structural Organization and Transcriptional Regulation of the Human beta_1-Adrenergic Receptor Gene
- Principal Investigator
  
  MATSUI Hiroaki
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Psychiatric science
- Research Institution
  ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE
Biochemical and Pharmacological Research on Affective Disorders from the Aspect of the Mechanism of Neural Transmission and Intracellural Signal Transduction
- Principal Investigator
  
  HIGUCHI Teruhiko
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Psychiatric science
- Research Institution
  Gunma University Scholl of Medicine
  Saitama Medical University
The Biochemical Study on Central monoaminergic Receptors・membrane associated Substances and a Mode of Action of AntidepressantsPrincipal Investigator
- Principal Investigator
  
  ASAKURA Mikio
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  St. Marianna University School of Medicine

All 2010 2008

All Journal Article Presentation

[Journal Article] Chronic trifluoperazine treatment increased P-glycoprotein in the rat brain.2010
- Author(s)
  Osada K, Ogawa Y, Haga T, Nakano M, Tanaka D, Sasuga Y, Asakura M, Yamaguchi N
- Journal Title
  
  J.St.Marianna Univ 38(1)
  
  Pages: 7-13
- NAID
  40018813569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591380
[Journal Article] Fluvoxamine and sigma-1 receptor agonists dehydroepiandrosterone (DHEA)-sulfate induces the Ser473-phosphorylation of Akt-1 in PC12 cells.2010
- Author(s)
  Nakano M, Osada K, Misonoo A, Fujiwara K, Takahashi M, Ogawa Y, Haga T, Kanai S, Tanaka D, Sasuga Y. Yanagida T, Asakura M, Yamaguchi N
- Journal Title
  
  Life Sciences 86
  
  Pages: 309-314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591380
[Presentation] Fluvoxamine and Sigma-1 Receptor Agonists Dehydroepiandrosterone (DHEA)-sulfate Induces the Ser473-phosphorylation of Akt-1 in PC12 Cells.2010
- Author(s)
  Osada K, Haga T, Ogawa Y, Matsui H, Nakano M, Asakura M, Yamaguchi N
- Organizer
  41th Annual Meeting of Neuroscience
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-20591380
[Presentation] Antidepressants induces phosphorylation of Akt in PC12.2008
- Author(s)
  Osada K, Nakano M, Misonoo A, Kanai S, Tanaka D, Ootmono M, Sasuga Y, Takahashi K. Ogawa Y, Haga T, Asakura M
- Organizer
  38rd Annual Meeting of Neuroscience
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-20591380

1. MATUI Hiroaki (90181685)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
2. OSADA Kenichi (20233504)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
3. SASUGA Yasuo (60308450)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. HIROI Tomoko (20238398)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YAMADA Mituhiko (60240040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KIDA Satoshi (80301547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MIYOSHI Hiroshi (80322519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KATOU Tomohiro (80233807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MISONOO Atushi (20410128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. GAWA Yuriko (90449398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. TANAKA Daisuke (80410124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. INO Miyuki (20203218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TSUKAMOTO Tohru (30171979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HIGUCHI Teruhiko (90105883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SHIBUYA Haruo (10158959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KOYAMA Tsukasa (10113557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NOMURA Soichiro (80113091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MIKUNI Masahiko (00125353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 加藤進昌 (10106213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 山脇成人

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ASAKURA Mikio 朝倉 幹雄

朝倉 幹雄 アサクラ ミキオ

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新規抗うつ薬結合蛋白質過剰発現マウスのストレス耐性とうつ病モデル動物の検討Principal Investigator

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The Biochemical Study on Central monoaminergic Receptors・membrane associated Substances and a Mode of Action of AntidepressantsPrincipal Investigator

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[Journal Article] Chronic trifluoperazine treatment increased P-glycoprotein in the rat brain.2010

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NAID

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[Journal Article] Fluvoxamine and sigma-1 receptor agonists dehydroepiandrosterone (DHEA)-sulfate induces the Ser473-phosphorylation of Akt-1 in PC12 cells.2010

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[Presentation] Fluvoxamine and Sigma-1 Receptor Agonists Dehydroepiandrosterone (DHEA)-sulfate Induces the Ser473-phosphorylation of Akt-1 in PC12 Cells.2010

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Organizer

Year and Date

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[Presentation] Antidepressants induces phosphorylation of Akt in PC12.2008

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ASAKURA Mikio 朝倉幹雄

朝倉幹雄アサクラミキオ