Wachi Masaaki 和地正明

… Alternative Names

和地正明ワチマサアキ

WACHI Masaaki 和地正明

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Researcher Number	90192822
Other IDs
External Links
Affiliation (Current)	2025: 東京科学大学, 生命理工学院, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 東京工業大学, 生命理工学院, 教授 2017: 東京工業大学, 生命理工学院, 教授 2013 – 2015: 東京工業大学, 生命理工学研究科, 教授 2013: 東京工業大学, 大学院・生命理工学研究科, 教授 2008 – 2010: Tokyo Institute of Technology, 大学院・生命理工学研究科, 准教授 … More 2000 – 2005: 東京工業大学, 大学院・生命理工学研究科, 助教授 1998 – 2000: 東京工業大学, 生命理工学部, 助教授 1994 – 1995: 東京工業大学, 生命理工学部, 講師 1991 – 1993: 東京工業大学, 生命理工学部, 助手 Less
Review Section/Research Field	Principal Investigator 応用微生物学・応用生物化学 / Applied microbiology / Medium-sized Section 38:Agricultural chemistry and related fields / Bioorganic chemistry / Biological Sciences Except Principal Investigator 応用微生物学・応用生物化学 / Applied microbiology / 矯正・小児・社会系歯学 / 応用微生物学・発酵学 / Science and Engineering
Keywords	Principal Investigator Hfq / RNaseE / RNase G / FtsZ / カルシウム / cafA / 大腸菌 / adhE / RNase E / mRNA … More / 酸化ストレス / 阻害剤 / アルコールデヒドロゲナーゼ / GcvB small RNA / アラニルグルタミン / グルタミン / GcvB sRNA / カタボライト抑制 / 代謝制御 / アミノ酸 / ジペプチド / RNA metabolism / stress protection / Dps / cra / エノラーゼ / 酸耐性 / Gad / 糖代謝 / ピルビン酸 / バリン / RNA代謝 / ストレス防御 / oxidative stress / iron ion / DNA損傷 / Hfqタンパク質 / 細胞増殖 / rRNA / RNaseG / 鉄イオン / PBGS / マラリア / hemB / ALAS / hemA / ポルフォビリノーゲン合成酵素 / 5-アミノレブリン酸 / ポルフィリン / 抗マラリア薬 / アラレマイシン / 転写 / アクチン様細胞骨格 / 蛍光標識誘導体 / 溶菌 / PBP1B / A22 / MreB / アクチン様細胞骨格タンパク質 / 微生物学 / 間接免疫蛍光 / 細胞分裂 / シャペロン / GroEL / バルジ / ペニシリン / エンドリボヌクレアーゼ / 16S rRNA / 超ラセン構造 / rpoB / dinD / SOS / pcsA / 細胞骨格 / 細胞周期 / mukA / ams … More Except Principal Investigator H-NS / oriC / ATPase / Corynebacterium glutamicum / P.gingivalis / rRNA / ams / cafA / 細胞周期 / cell division / mre / SopA / 細胞分裂 / 大腸菌 / Hfq / 抗生物質 / RNA代謝 / γ -Glutamyltranspeptidase / Cell wall / Cysteine / Alanine / NADH dehydrogenase / Brevibacterium Oactofermentum / γ-グルタミルトランスフェラーゼ / 呼吸鎖 / γ-グルタミルトランスペプチターゼ / γ-グルタミルトランスペプチダーゼ / 細胞壁 / システイン / アラニン / NADH脱水素酵素 / ATP ase / Cell division / Peridontal diseases / Peptidoglycan / 歯周病 / ペプチドグリカン / plasmid partitioning / centromere / DNA methylation / replication origin / cohesion of sister chromosomes / control of replication initiation / chromosome partitioning / chromosome segregation / ヒストン様蛋白 / 修飾環 / モーター蛋白 / プロテアーゼ / トポイソメラーゼ / ヒトセントロメア / 人工ミニ染色体 / 枯草菌 / ミニFプラスミドDNA / oriCDNA / 免疫蛍光顕微鏡法 / 大腸菌染色体 / DnaA / SeqA / 複製開始 / プラスミド分配 / セントロメア / DNAメチレーション / 複製起点 / 姉妹染色体の対合 / 複製開始の調節 / 染色体分配 / 染色体分離 / Cytoskeltal protein / Calcium / Cell cycle / Histone-like protein / 超ラセン構造 / DNA gyrase / アルコールデヒドロゲナーゼ / 細胞骨格様蛋白質 / カルシウム / ヒストン様蛋白質 / F plasmid / replication / Escherichia coli / HーNS / DNAー膜複合体 / sopA / oric / Fプラスミド / 染色体複製 / Hfｑ / ストレスファイバー / Green fluorescence protein / ルシフェラーゼ / 圧力刺激 / 有機溶媒 / heat shock protein / 電圧刺激 / ストレス応答 / 細胞骨格 / リポソーム / 圧力応答 / 酸化ストレス / 電気刺激 / サイトカイン / NF-κB / アクチン結合蛋白質 / 高圧応答細胞 / 活性酸素 / 破骨細胞 / marRABオペロン / 分化誘導 / 電位印加 / アクチン / 細胞モデル / 加圧応答遺伝子 / 好圧性細菌 / 桿菌形態形成 / S-benzylisothiourea / mar遺伝子 / rpoSプロモーター Less

Catabolite repression of amino acid metabolismPrincipal Investigator
- Principal Investigator
  
  和地正明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Tokyo Institute of Technology
Mechanism of recovery from Hfq-induced growth inhibition by ansamycin family antibiotics
- Principal Investigator
  
  TAKADA AYAKO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied microbiology
- Research Institution
  Tokyo Institute of Technology
Development of anti-malarial drugs targeting porphyrin biosynthesisPrincipal Investigator
- Principal Investigator
  
  Wachi Masaaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Tokyo Institute of Technology
Screening for novel antibiotics targeting RNA metabolism
- Principal Investigator
  
  TAKADA Ayako
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied microbiology
- Research Institution
  Tokyo Institute of Technology
Functional analysis of bacterial actin-like cytoskeletal proteins by using inhibitorsPrincipal Investigator
- Principal Investigator
  
  WACHI Masaaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Tokyo Institute of Technology
Functional analysis of Escherichia coli RNase G and its application for construction of protein expression systemPrincipal Investigator
- Principal Investigator
  
  WACHI Masaaki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Tokyo Institute of Technology
大腸菌の細胞分裂におけるGroELシャペロンの役割Principal Investigator
- Principal Investigator
  
  和地正明
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Institute of Technology
Mechanism of regulation of E. coli cell duplication by DNA-, RNA- binding protein HfqPrincipal Investigator
- Principal Investigator
  
  WACHI Masaaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Tokyo Institute of Technology
環境シグナル応答細胞の創製
- Principal Investigator
  
  相澤益男, NAGAI Kazuo
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
Molecular Understanding of the Coryne-form Bacteria and its Industrial Application
- Principal Investigator
  
  TOMTA Fusao
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  HOKKAIDO UNIVERSITY
Development of antisense therapy for periodontal diseases targeted bacterial cell-division related genes
- Principal Investigator
  
  TAKEHARA Tadamichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kyushu Dental College
Dynamics of chromosome partition apparatus
- Principal Investigator
  
  HIRAGA Sota
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Institute of Molecular Embryology and Genetics, Kumamoto University
大腸菌の染色体分配と細胞分裂のメカニズムPrincipal Investigator
- Principal Investigator
  
  和地正明
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Tokyo Institute of Technology
大腸菌の細胞分裂を制御する因子の解析Principal Investigator
- Principal Investigator
  
  和地正明
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Tokyo Institute of Technology
大腸菌細胞の形態形成・細胞分裂の制御機構の解析Principal Investigator
- Principal Investigator
  
  和地正明
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Tokyo Institute of Technology
Roles of protein phosphorylation, calcium ion and cytoskeltal proteins in bacterial cell cycle.
- Principal Investigator
  
  NAGAI Kazuo
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Tokyo Institute of Technology
Studies on regulatory factors for bacterial cell cycle.
- Principal Investigator
  
  NAGAI Kazuo
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用微生物学・発酵学
- Research Institution
  Tokyo Institute of Technology

[Journal Article] 二次代謝酵素から一次代謝酵素への進化モデル2023
- Author(s)
  川口潤、和地正明
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 81 Pages: 400-401
- Data Source
  KAKENHI-PROJECT-22K19129
[Journal Article] A secondary metabolic enzyme functioned as an evolutionary seed of a primary metabolic enzyme2022
- Author(s)
  Kawaguchi J, Mori H, Iwai N, Wachi M
- Journal Title
  
  Mol. Biol. Evol.
  
  Volume: 39 Issue: 8
- DOI
  10.1093/molbev/msac164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19129
[Journal Article] Effects of EGTA on cell surface structures of Corynebacterium glutamicum2017
- Author(s)
  Theresia Natalia Maria、Aida Kohei、Takada Ayako、Iwai Noritaka、Wachi Masaaki
- Journal Title
  
  Archives of Microbiology
  
  Volume: 200 Issue: 2 Pages: 281-289
- DOI
  10.1007/s00203-017-1445-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14690
[Journal Article] Degradation of benzotrifluoride via the dioxygenase pathway in Rhodococcous sp. 0652402015
- Author(s)
  Kenichi Yano, Masaaki Wachi, Sakiko Tsuchida, Tomoya Kitazume, Noritaka Iwai
- Journal Title
  
  Bioscience, biotechnology, and Biochemistry
  
  Volume: 79 Issue: 3 Pages: 496-504
- DOI
  10.1080/09168451.2014.982502
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25850067, KAKENHI-PROJECT-25660088
[Journal Article] High crude violacein production from glucose by Escherichia coli engineered with interactive control of tryptophan pathway and violacein biosynthetic pathway.2015
- Author(s)
  Fang, M.Y., Zhang, C., Yang, S., Cui, J.Y., Jiang, P.X., Lou, K., Wachi, M., Xing, X.H.
- Journal Title
  
  Microb. Cell Fact.
  
  Volume: 14 Issue: 1 Pages: 8-8
- DOI
  10.1186/s12934-015-0192-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25660088
[Journal Article] A role of the transcriptional regulator LldR (NCgl2814) in glutamate metabolism under biotin-limited conditions in Corynebacterium glutamicum2013
- Author(s)
 Supkulsutra T, Maeda T, Kumagai K, Wachi M.
- Journal Title
 
 J. Gen. Appl. Microbiol.
 
 Volume: 59 Issue: 3 Pages: 207-214
- DOI
 10.2323/jgam.59.207
- NAID
 130004802243
- ISSN
 0022-1260, 1349-8037
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-25660088
[Journal Article] L-Glutamate Secretion by the N-Terminal Domain of the Corynebacterium glutamicum NCgl1221 Mechanosensitive Channel2013
- Author(s)
 Yamashita C., Hashimoto K., Kumagai K., Takada A., Kawasaki H. and Wachi M
- Journal Title
 
 Bioscience, Biotechnology, and Biochemistry
 
 Volume: 77 Issue: 5 Pages: 1008-1013
- DOI
 10.1271/bbb.120988
- NAID
 10031177589
- ISSN
 0916-8451, 1347-6947
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-23658073, KAKENHI-PROJECT-25660088
[Journal Article] A Secondary Structure in the 5' Untranslated Region of adhE mRNA Required for RNase G-Dependent Regulation2013
- Author(s)
 Ito K, Hamasaki K, Kayamori A, Nguyen PA, Amagai K, Wachi M.
- Journal Title
 
 Bioscience, Biotechnology, and Biochemistry
 
 Volume: 77 Issue: 12 Pages: 2473-2479
- DOI
 10.1271/bbb.130618
- NAID
 130003381972
- ISSN
 0916-8451, 1347-6947
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-25660088
[Journal Article] A requirement of ToIC and MDR efflux pumps for acid adaptation and GadAB induction in Escherichia coli.2011
- Author(s)
  Deininger KN, Horikawa A, Kitko RD, Tatsumi R, Rosner JL, Wachi M, Slonczewski JL.
- Journal Title
  
  PLoS One. 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] A role of the cspA gene encoding a mycolyltransferase in the growth under alkaline conditions of Corynebacterium glutamicum.2010
- Author(s)
  Takeshita R, Ito H, Wachi M
- Journal Title
  
  Biosci Biotechnol Riochem. 74
  
  Pages: 1617-1623
- NAID
  10027558199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin.2010
- Author(s)
  Heinemann IU, Schulz C, Schubert WD, Heinz DW, Wang YG, Kobayashi Y, Awa Y, Wachi M, Jahn D, Jahn M.
- Journal Title
  
  Antimicrob Agents Chemother. 54
  
  Pages: 267-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] Requirement of de novo synthesis of the OdhT protein in penicillin-induced glutamate production by Corynebacterium glutamicum.2010
- Author(s)
  Kim J, Fukuda H, Hirasawa T, Nagahisa K, Nagai K, Wachi M, Shimizu H.
- Journal Title
  
  Appl Microbiol Biotechnol. 86
  
  Pages: 911-920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] 大腸菌RNaseGによる解糖系び制御2010
- Author(s)
  和地正明
- Journal Title
  
  バイオサイエンスとインダストリー 68
  
  Pages: 34-38
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] 大腸菌RNase Gによる解糖系の制御2010
- Author(s)
  和地正明
- Journal Title
  
  バイオサイエンスとインダストリー 63
  
  Pages: 34-38
- NAID
  10026194999
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] A role of the cspA gene encoding a mycolyltransferase in the growth under alkaline conditions of Corynebacterium glutamicum2010
- Author(s)
  Takeshita R, Ito H, Wachi M
- Journal Title
  
  Biosci Biotechnol Biochem.
  
  Volume: 74 Pages: 1617-1623
- NAID
  10027558199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] The Corynebacterium glutamicum NCg12281 gene encoding an Base E/G family endoribonuclease can complement the Escherichia coli rng : cat mutation but not the rne-1 mutation.2009
- Author(s)
  Maeda T, Sakai T, Wachi M
- Journal Title
  
  Riosci Biotechnol Riochem. 73
  
  Pages: 2281-2286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] ToIC-dependent exclusion of porphyrins in Rscherichia coli.2008
- Author(s)
  Tatsumi R, Wachi M
- Journal Title
  
  J Bacterial. 190
  
  Pages: 6228-6233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] Anti-infectious effect of S-benzylisothiourea compound A22, which inhibits the actin-like protein, MreB, in Shigella flexneri.2008
- Author(s)
  Noguchi N, Yanagimoto K, Nakaminami H, Wakabayashi M, Iwai N, Wachi M, Sasatsu M.
- Journal Title
  
  Biol Pharm Bull. 31
  
  Pages: 1327-1332
- NAID
  110006792097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] Structural and functional characterization of the LIdR from Corynebacterium glutamicum : a transcriptional repressor involved in L-lactate and sugar utilization.2008
- Author(s)
  Gao YG, Suzuki H, Itou H, Zhou Y, Tanaka Y, Wachi M, Watanabe N, Tanaka I, Yao M.
- Journal Title
  
  Nucleic Acids Res. 36
  
  Pages: 7110-7123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] Distinctroles of two anaplerotic pathways in glutamate production induced by biotin limitation in Corynebacterium glutamicum.2008
- Author(s)
  Sato H, Orishimo K, Shirai T, Hirasawa T, Nagahisa K, Shimizu H, Wachi M
- Journal Title
  
  J Biosci Bioeng. 106
  
  Pages: 51-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380047
[Journal Article] Actin homology MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli.2006
- Author(s)
  Kruse, T., Blagoev, B, Lobner-Olesen, A., Wachi, M., Sasaki, K., Iwai, N., Mann, M., Gerdes, K.
- Journal Title
  
  Genes & Dev. 20
  
  Pages: 113-124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380059
[Journal Article] A decreased level of FtsZ is responsible for inviability of RNase E-deficient cells.2005
- Author(s)
  Takada, A., Nagai, K., Wachi, M.
- Journal Title
  
  Genes Cells 10
  
  Pages: 733-741
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380059
[Journal Article] MreB actin-mediated segregation of a specific region of a bacterial chromosome.2005
- Author(s)
  Gitai, Z., Dye, N.A., Reisenauer, A., Wachi, M., Shapiro, L.
- Journal Title
  
  Cell 120
  
  Pages: 329-341
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380059
[Journal Article] FtsZ-dependent localization of GroEL protein at possible division sites.2004
- Author(s)
  Ogino, H., Wachi, M., Ishii, A., Iwai, N., Nishida, T., Yamasa, S., Nagai, K., Sugai, M.
- Journal Title
  
  Genes Cells 9
  
  Pages: 765-771
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380059
[Journal Article] A Corynebacterium glutamicum rnhA recG double mutant showing lysozyme-sensitivity, temperature-sensitivity growth, and UV-sensitivity.2003
- Author(s)
  Hiwasawa, T., Kumagai, Y., Nagai, K., Wachi, M.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 67
  
  Pages: 2416-2424
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380059
[Journal Article] RNase ES of Streptomyces coelicolor A3(2) can complement the rne and rng mutations in Escherichia coli.2003
- Author(s)
  Inagawa, T., Okamoto, S., Wachi, M., Ochi, K.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 67
  
  Pages: 1767-1771
- NAID
  110002694299
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380059
[Patent] ピルビン酸の製造方法及びL-バリンの製造方法2004
- Inventor(s)
  和地正明
- Industrial Property Rights Holder
  (財)理工学振興会
- Industrial Property Number
  2004-154989
- Filing Date
  2004-05-25
- Data Source
  KAKENHI-PROJECT-15380059
[Presentation] 細菌が持つセリンパルミトイル転移酵素ホモログが大腸菌に及ぼす特異な影響2024
- Author(s)
  川口潤、岩井伯隆、和地正明
- Organizer
  第18回日本ゲノム微生物学会年会、2024年3月12日、かずさアカデミアホール（千葉県木更津市）
- Data Source
  KAKENHI-PROJECT-22K19129
[Presentation] インドールによるGAD 発現抑制におけるGadX とGadW の役割2024
- Author(s)
  林弘健、神田健、岩井伯隆、和地正明
- Organizer
  第18回日本ゲノム微生物学会年会、2024年3月12日、かずさアカデミアホール（千葉県木更津市）
- Data Source
  KAKENHI-PROJECT-22K19129
[Presentation] 二次代謝酵素が一次代謝酵素へ進化した痕跡2023
- Author(s)
  川口潤、森ひかる、岩井伯隆、和地正明
- Organizer
  第17回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19129
[Presentation] コリネ型細菌のミコール酸生合成欠損変異株の性状解析2023
- Author(s)
  須之内愛、岩井伯隆、和地正明
- Organizer
  第75回日本生物工学会大会、2023年9月4日、名古屋大学東山キャンパス（名古屋市）
- Data Source
  KAKENHI-PROJECT-22K19129
[Presentation] 大腸菌におけるジペプチドAla-Gln によるグルタミン代謝の制御2023
- Author(s)
  秋元美月、岩井伯隆、和地正明
- Organizer
  第75回日本生物工学会大会、2023年9月3日、名古屋大学東山キャンパス（名古屋市）
- Data Source
  KAKENHI-PROJECT-22K19129
[Presentation] 二次代謝酵素から一次代謝酵素へ2023
- Author(s)
  和地正明
- Organizer
  酵素工学研究会第90回講演会、2023年11月10日、東京農工大学小金井キャンパス（東京都小金井市）
- Invited
- Data Source
  KAKENHI-PROJECT-22K19129
[Presentation] Hfqが関わるRNA代謝を標的とした新規薬剤の探索2018
- Author(s)
  高田綾子、和地正明
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-15K14690
[Presentation] A New Screening System for Compounds Targeting HFQ-Mediated RNA Metabolism2017
- Author(s)
  Ayako Takada and Masaaki Wachi
- Organizer
  International Union of Microbiological Societies 2017 (IUMS2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14690
[Presentation] アラレマイシン生産菌Streptomyces sp. A012304ノポルホビリノーゲン合成酵素の特性2016
- Author(s)
  上田沙蘭、岩井伯隆、和地正明
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25660088
[Presentation] 抗生物質アラレマイシンの生合成経路2016
- Author(s)
  森ひかる、岩井伯隆、和地正明
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25660088
[Presentation] Treasure hunting: Screening of antibiotics with a new target of action2015
- Author(s)
  Wachi, M.
- Organizer
  56th international symposium of the Korean Society of Life Science
- Place of Presentation
  Changwon, Korea
- Year and Date
  2015-08-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25660088
[Presentation] Hfqが関わるRNA代謝を標的とした新規薬剤の探索2015
- Author(s)
  高田綾子、和地正明
- Organizer
  第67回日本生物工学会
- Place of Presentation
  城山観光ホテル（鹿児島県）
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-15K14690
[Presentation] 大腸菌hemB欠損株を宿主としたPBGS異種発現によるアラレマイシン感受性の評価系の構築2013
- Author(s)
  矢野寛明、岩井伯隆、和地正明
- Organizer
  日本生物工学会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-25660088
[Presentation] Screening for inhibitors of Hfq - mediated RNA metabolism2013
- Author(s)
  Ayako Takada, Masaaki Wachi
- Organizer
  12th International Symposium on the Genetics of Industrial Microorganisms (GIM-2013)
- Place of Presentation
  Cancun Convention Center(メキシコ)
- Year and Date
  2013-06-26
- Data Source
  KAKENHI-PROJECT-23658073
[Presentation] Role of NCgl1221 mechanosnstive channel in glutamate production by Corynebacterium glutamicum.2013
- Author(s)
  Wachi M, Yamashita C.
- Organizer
  Genetics of Industrial Microorganisms
- Place of Presentation
  Cancum, Mexico
- Data Source
  KAKENHI-PROJECT-25660088
[Presentation] Screening for inhibitors of Hfq-mediated RNA metabolism.2013
- Author(s)
  Takada A, Wachi M.
- Organizer
  Genetics of Industrial Microorganisms
- Place of Presentation
  Cancum, Mexico
- Data Source
  KAKENHI-PROJECT-25660088
[Presentation] RNA 代謝を標的とする新規薬剤の探索2013
- Author(s)
  高田綾子, 和地正明
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学(宮城)
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-23658073
[Presentation] A new antibiotic alaremycin inhibits porphobilinogen synthase, the initial step of the porphyrin biosynthesis.2010
- Author(s)
  和地正明
- Organizer
  11th International Symposium on the Genetics of Industrial Microorganisms
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2010-06-30
- Data Source
  KAKENHI-PROJECT-20380047
[Presentation] アラレマイシンによるポルフィリン合成系ポルフォビリノーゲン合成酵素の阻害2010
- Author(s)
  和地正明
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20380047
[Presentation] A new antibiotic alaremycin inhibits porphobilinogen synthase, the initial step of the porphyrin biosynthesis2010
- Author(s)
 Masaaki Wachi
- Organizer
 11^<th> International Symposium on the Genetics of Industrial Microorganisms
- Place of Presentation
 Australia
- Year and Date
 2010-06-30
- Data Source
 KAKENHI-PROJECT-20380047
[Presentation] アラレマシンによるポルフィリン合成系ポルフォビリノーゲン合成酵素の阻害2010
- Author(s)
  和地正明
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  東京
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20380047
[Presentation] RNase G変異株を用いたmRNAの安定化によるタンパク質過剰発現系2010
- Author(s)
  和地正明
- Organizer
  第62回日本生物工学会大会
- Place of Presentation
  宮崎
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-20380047
[Presentation] アクチン様タンパク質MreB阻害剤A22を用いた桿菌形態形成機構の解析2009
- Author(s)
  和地正明
- Organizer
  第8 2回日本細菌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-20380047
[Presentation] アクチン様タンパク質MreB阻害剤A22を用いた桿菌形態形成機構の解析2009
- Author(s)
  和地正明、高田綾子、岩井伯隆
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-20380047
[Presentation] アラレマイシン生産菌Streptomyces sp. A012304の2種類の5-アミノレブリン酸合成遺伝子の解析
- Author(s)
  岩井伯隆、森ひかる、和地正明
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25660088
[Presentation] アラレマイシン生産菌の２つのALA生合成酵素ホモログの機能解析
- Author(s)
  森ひかる、岩井伯隆、和地正明
- Organizer
  第9回日本ゲノム微生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-06 – 2015-03-08
- Data Source
  KAKENHI-PROJECT-25660088

1. NAGAI Kazuo (00011974)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. TAKADA Ayako (20401565)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. 相澤益男 (00016742)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HIRAGA Sota (40027321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OHYA Yoshikazu (20183767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OGURA Teru (00158825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NISHIMURA Akiko (20142002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HORIUCHI Takashi (60108644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKEHARA Tadamichi (00038879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. AKIFUSA Sumio (40295861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ANSAI Toshihiro (80244789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TOMTA Fusao (60217536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KATSUMATA Ryoichi (60292257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MATSUSHITA Kazunobu (50107736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KUMAGAI Hidehiko (70027192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAKAMORI Shigeru (00254243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 青野力三 (30126643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 宝谷紘一 (80025444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 加藤潤一 (10194820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 岡崎恒子 (10022584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 松澤洋 (00011966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YAMAGISHI Jyun-ichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 加藤千明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. IWAI Noritaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Wachi Masaaki 和地 正明

和地 正明 ワチ マサアキ

WACHI Masaaki 和地 正明

Research Projects

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Co-Researchers

Catabolite repression of amino acid metabolismPrincipal Investigator

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Development of anti-malarial drugs targeting porphyrin biosynthesisPrincipal Investigator

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Functional analysis of bacterial actin-like cytoskeletal proteins by using inhibitorsPrincipal Investigator

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Functional analysis of Escherichia coli RNase G and its application for construction of protein expression systemPrincipal Investigator

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大腸菌の細胞分裂におけるGroELシャペロンの役割Principal Investigator

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Mechanism of regulation of E. coli cell duplication by DNA-, RNA- binding protein HfqPrincipal Investigator

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大腸菌の染色体分配と細胞分裂のメカニズムPrincipal Investigator

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大腸菌の細胞分裂を制御する因子の解析Principal Investigator

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Wachi Masaaki 和地正明

和地正明ワチマサアキ

WACHI Masaaki 和地正明