Ikuta Koichi 生田宏一

… Alternative Names

IKUTA Koichi 生田宏一

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Researcher Number	90193177
Other IDs
Affiliation (Current)	2024: 京都大学, 医学研究科, 研究員
Affiliation (based on the past Project Information) *help	2024: 京都大学, 医学研究科, 研究員 2022 – 2023: 京都大学, 医生物学研究所, 教授 2020 – 2021: 京都大学, ウイルス・再生医科学研究所, 教授 2016 – 2018: 京都大学, ウイルス・再生医科学研究所, 教授 2013 – 2015: 京都大学, ウイルス研究所, 教授 … More 2009 – 2011: Kyoto University, ウイルス研究所, 教授 2002 – 2007: 京都大学, ウイルス研究所, 教授 2003: Kyoto-Univ., Dept. of Med, Prof., 医学研究科, 教授 2002: 京都大学, ウイルス研究科, 教授 1999 – 2001: 京都大学, 大学院・医学研究科, 助教授 1998 – 2001: Kyoto university Graduate School of Medicine Associate Professor, 医学研究科, 助教授 1998: 京大, 医学研究科, 助教授 1997: 京都大学, 医学研究所, 助教授 1996: 京都大学, 医学研究科, 助教授 1994 – 1995: 東京大学, 医学部, 客員助教授 1993 – 1995: 東京大学, 医学部(医), 客員助教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Immunology / Immunology / Basic Section 49070:Immunology-related / Biological Sciences / 免疫の制御機構 / Immunology / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Experimental pathology / Pathological medical chemistry … More Except Principal Investigator … More Biological Sciences / Basic Section 54040:Metabolism and endocrinology-related / Applied veterinary science / Endocrinology Less
Keywords	Principal Investigator サイトカインレセプター / T細胞 / サイトカイン / T細胞抗原受容体 / Stat / 転写 / インターロイキン7 / シグナル伝達 / ストローマ細胞 / IL-7 … More / γδT細胞 / グルココルチコイド / DNA組換え / 微小環境 / 免疫学 / リンパ組織 / 転写共役因子 / ヒストンアセチル化 / STAT / IL-7レセプター / 感染症 / NK細胞 / Tリンパ球 / DNA recombination / signal transduction / IL-15 / 免疫応答 / インターロイキン / レトロウィルス / トランスジェニックマウス / 標的遺伝子組み換え / 胸腺 / T細胞レセプター / 腫瘍免疫 / 自然免疫 / 発生・分化 / 生体分子 / 骨芽細胞 / 自然リンパ球 / Bリンパ球 / retrovirus / transcriptional coactivator / histone acetylation / γδ T cell / cytokine receptor / レトロウイルス / IL-7 receptor / Bcl-2 / 免疫組織 / NKT細胞 / 補助刺激分子 / 樹状細胞 / マウス / N配列 / 造血幹細胞 / 抗ウイルス免疫応答 / 血管内皮細胞 / 関節リウマチ / 実験的自己免疫性脳脊髄炎 / Th17細胞 / 自己免疫疾患 / 生理学 / 内科 / 糖質コルチコイド / 適応免疫 / 内分泌系 / 概日リズム / ステロイド / リンパ球 / costimulatory molecule / immune response / dendritic cell / interleukin / T cell / IL-レセプター / chromatin / histone modification / T cell antigen receptor / cytokine / サイトカインレセプタ / クロマチン / ヒストン修飾 / γδT cell / transgenic mouse / gammadelta T cell / 免疫細胞 / GFP / 胸腺上皮細胞 / 遺伝子改変マウス / γδ T細胞 / 小腸上皮内リンパ球 / B細胞 / IL-7 レセプター / 転写誘導 / V-J組換え / レセプター / トロンボポイエチン / 巨核球 / 癌遺伝子 / サイトカイン・レセプター / RT-PCR / 胎児胸腺器官培養 / PCR / γδ型T細胞 … More Except Principal Investigator サイトカイン / シグナル伝達 / ノックアウトマウス / ジーンターゲッティング / 胚幹細胞 / 脂質関連マクロファージ / M2マクロファージ / 肥満 / インスリン抵抗性 / 2型糖尿病 / Glucocorticold / γδ T cell / Signal transduction / Cytokine / 樹状細胞 / γδ T細胞 / グルココルチコイド / γδT細胞 / TSH receptor / Transgenic mouse / Autoimmune thyroid disease / Grave's disease / TSHレセプター抗体 / トランスジェニックマウル / TSHレセプター / トランスジェニックマウス / 甲状腺機能亢進症 / バセドウ病 / CD94 / NK細胞 / STAT / BLNK / プレB細胞レセプター / マクロファージ活性化 / IL-7レセプター / PLCγ2 / Ly49Q / 抗原提示細胞 / ヒストンアセチル化 / T細胞レセプター遺伝子 / Sab / Btk / チロシンリン酸化 / B細胞分化 / クローン優位性 / ケモカイン / ジーンターゲティング / 発作性夜間血色素尿症(PNH) / V-J組換え / コンディショナルターゲティング / トランスポゾンシステム / サイトカインレセプター / 突然変異マウス / レトロウイルスベクター / コモンマーモセット / 選択的増幅遺伝子 / 造血幹細胞 / 遺伝子治療 / ES細胞 / 標的組み換え法 / 変異導入 Less

The mechanism how adipose tissue M2 macrophages regulate insulin sensitivity
- Principal Investigator
  
  戸邉一之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  University of Toyama
Control of immune response and tissue homeostasis by novel IL-15-dependent innate lymphocytesPrincipal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University
Induction of autoimmune diseases by glucocorticoidsPrincipal Investigator
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Kyoto University
IL-15-producing microenvironment supporting innate lymphoid cells and its role in diseasesPrincipal Investigator
- Principal Investigator
  
  Ikuta Koichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University
Control of innate immune cells, chronic inflammation and infection by cytokine-producing immune microenvironmentPrincipal Investigator
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
Control of dynamics and function of T cells by glucocorticoids via IL-7 receptor expressionPrincipal Investigator
- Principal Investigator
  
  Ikuta Koichi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
サイトカイン産生性免疫微小環境の機能解析Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ＩＬ－１５産生性ストローマ細胞の局所機能の解明Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
サイトカイン産生性免疫微小環境の可視化と機能解析Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Distribution and function of IL-15-producing cells in vivoPrincipal Investigator
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Distribution and function of IL-7-producing cellsPrincipal Investigator
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Analysis of IL-7 receptor and application for biological protection
- Principal Investigator
  
  MAKI Kazushige
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Kyoto University
IL-7レセプターの発現制御による免疫監視システムの形成と維持機構Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
IL-7レセプターを指標としたB細胞記憶形成機構の解明Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Role of IL-7 receptor in selection and memory formation of T cellsPrincipal Investigator
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
転写因子Ikarosによる胸線T細胞の細胞周期と細胞死の制御Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
IL-7レセプターの発現制御による免疫監視システムの形成と維持機構Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
獲得免疫の成立過程におけるIL-7レセプターの機能Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
リンパ系前駆細胞の生成過程におけるIL-7レセプターの機能Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
獲得免疫の成立過程におけるIL-7レセプターの機能Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
T細胞分化におけるIL-7レセプターによる細胞周期と細胞死の制御Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ヒストン・メチル化によるTCRβ遺伝子座の対立遺伝子排除の制御Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Recombination control of lymphocyte antigen receptor loci by chromati modificationPrincipal Investigator
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
A transgenic model of Gcaves disease bearing human autoantibody genes
- Principal Investigator
  
  AKAMIZU Takashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  KYOTO UNIVERSITY
リンパ球の初期分化を誘導・制御するシグナル伝達機構
- Principal Investigator
  
  烏山一
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Functional analysis of intracellular signaling molecules in T cell differentiation by IL-7 receptor-deficient micePrincipal Investigator
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  KYOTO UNIVERSITY
Induction mechanism of V-J recombination by signaling molecules of the IL-7 receptorPrincipal Investigator
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  KYOTO UNIVERSITY
IL-7レセプターによるTCRγ遺伝子のV-J組換え誘導機構Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
造血細胞の遺伝子操作
- Principal Investigator
  
  小澤敬也
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Jichi Medical University
IL-クレセプターによるTCRγ遺伝子のV-J組み換え誘導機構Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
Analysis of lymphpcyte differentiation and growth mechanism by IL-7 receptor deficient micePrincipal Investigator
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  免疫の制御機構
- Research Institution
  KYOTO UNIVERSITY
IL-7レセプター欠失マウスによるリンパ球初期分化機構の解析Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  免疫の制御機構
- Research Institution
  Kyoto University
胚幹細胞への欠失変異導入法の開発
- Principal Investigator
  
  宮崎純一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
マウス発生工学によるc-mplとトロンボポイエチンを介した巨核球増殖機構の解析Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
胚幹細胞への欠失変異導入法の開発
- Principal Investigator
  
  宮崎純一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
胎児期造血幹細胞のストローマ細胞による増幅と分化能の変化Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
標的遺伝子組み換えによる造血幹細胞の新しい受容体型癌遺伝子c-mplの解析Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
標的遺伝子組み換えと胚盤胞相補法によるサイトカイン受容体遺伝子の機能解析Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
胚幹細胞への欠失変異導入法の開発
- Principal Investigator
  
  宮崎純一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
造血幹細胞レベルでのT細胞レセプターN配列挿入の調節機構Principal Investigator
- Principal Investigator
  
  生田宏一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo

[Book] Role of the IL-7 receptor inγδT-cell development from hematopoietic stem cells. In "Hematopoietic Stem Cell Biology". Kondo, M., ed.2009
- Author(s)
  Ikuta, K. and Tani-ichi, S.
- Publisher
  Humana Press Inc
- Data Source
  KAKENHI-PROJECT-21590531
[Journal Article] Retinoic acid receptor activity is required for the maintenance of type 1 innate lymphoid cells2023
- Author(s)
  Asahi, T., Abe, S., Tajika, Y., Rodewald, H. R., Sexl, V., Takeshima, H., and Ikuta, K.
- Journal Title
  
  Int. Immunol.
  
  Volume: 35 Issue: 3 Pages: 147-155
- DOI
  10.1093/intimm/dxac057
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-21J15058
[Journal Article] High-throughput identification and quantification of single bacterial cells in the microbiota2022
- Author(s)
  Jin, J., Yamamoto, R., Takeuchi, T., Cui, G., Miyauchi, E., Hojo, N., Ikuta, K., Ohno, H., and Shiroguchi, K.
- Journal Title
  
  Nat. Commun.
  
  Volume: 13 Issue: 1 Pages: 863-863
- DOI
  10.1038/s41467-022-28426-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21525, KAKENHI-PLANNED-18H05411, KAKENHI-PROJECT-19H01030, KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-20H03501
[Journal Article] Physiological concentrations of glucocorticoids induce pathological DNA double-strand breaks2022
- Author(s)
  Akter Salma、Shimba Akihiro、Ikuta Koichi、Mahmud Md. Rasel Al、Yamada Shintaro、Sasanuma Hiroyuki、Tsuda Masataka、Sone Masakatsu、Ago Yukio、Murai Kenichi、Tanaka Hisashi、Takeda Shunichi
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 1 Pages: 53-67
- DOI
  10.1111/gtc.12993
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07148, KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-20K09539
[Journal Article] Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies2022
- Author(s)
  Kansler, E. R., Dadi,S., Krishna, C., Nixon, B. G., Stamatiades E. G., Liu, M., Kuo, F., Zhang, J., Zhang, X., Capistrano, K., Blum, K. A., Weiss, K., Kedl, R. M., Cui, G., Ikuta, K., Chan, T. A., Leslie, C. S., Hakimi, A. A. and Li, M. O.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 23 Issue: 6 Pages: 904-915
- DOI
  10.1038/s41590-022-01213-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03501
[Journal Article] Interleukin-7 receptor signaling is crucial for enhancer-dependent TCRd germline transcription mediated through STAT5 recruitment2022
- Author(s)
  Rodriguez-Caparros, A., Tani-ichi, S., Casal, A., Lopez-Ros, J., Sune, C., Ikuta, K., and Hernandez-Munain, C.
- Journal Title
  
  Front. Immunol.
  
  Volume: 13 Pages: 943510-943510
- DOI
  10.3389/fimmu.2022.943510
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03501
[Journal Article] A circulating subset of iNKT cells mediates antitumor and antiviral immunity2022
- Author(s)
  Cui G, Shimba A, et.al
- Journal Title
  
  Science Immunology
  
  Volume: 7 Issue: 76 Pages: 8760-8760
- DOI
  10.1126/sciimmunol.abj8760
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07545, KAKENHI-PROJECT-22K07086, KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-20K21522, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-20K17580, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-21J15058
[Journal Article] IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity2022
- Author(s)
  Das Gupta, D., Paul, C., Samel, N., Bieringer, M., Staudenraus, D., Marini, F., Raifer, H., Menke, L., （８人） Helmprobst, F., Buchholz, M., Roth, K., Bastian, L., Hartmann, A. M., Baldus, C., Ikuta, K., Neubauer, A., Burchert, A., Jack, H-M., Klein, M., Bopp, T., Stiewe, T., Pagenstecher, A., and Lohoff, M.
- Journal Title
  
  Cell Death Differ.
  
  Volume: 29 Issue: 11 Pages: 2163-2176
- DOI
  10.1038/s41418-022-01005-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03501
[Journal Article] Androgens Alleviate Allergic Airway Inflammation by Suppressing Cytokine Production in Th2 Cells2022
- Author(s)
  Ejima Aki、Abe Shinya、Shimba Akihiro、Sato Susumu、Uehata Takuya、Tani-ichi Shizue、Munakata Satoru、Cui Guangwei、Takeuchi Osamu、Hirai Toyohiro、Kato Shigeaki、Ikuta Koichi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 209 Issue: 6 Pages: 1083-1094
- DOI
  10.4049/jimmunol.2200294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-20H03501
[Journal Article] Estradiol suppresses psoriatic inflammation in mice by regulating neutrophil and macrophage functions2022
- Author(s)
  Adachi Akimasa、Honda Tetsuya、Egawa Gyohei、Kanameishi Shuto、Takimoto Riko、Miyake Toshiya、Hossain Md Razib、Komine Mayumi、Ohtsuki Mamitaro、Gunzer Matthias、Ikuta Koichi、Kabashima Kenji
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 150 Issue: 4 Pages: 909-919.e8
- DOI
  10.1016/j.jaci.2022.03.028
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08428, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-20K08661, KAKENHI-PROJECT-20H05697
[Journal Article] Prolonged high-intensity exercise induces fluctuating immune responses to herpes simplex virus infection via glucocorticoids.2021
- Author(s)
  Adachi A, Honda T, Dainichi T, Egawa G, Yamamoto Y, Nomura T, Nakajima, S, Otsuka A, Maekawa M, Mano N, Koyanagi N, Kawaguchi Y, Ohteki T, Nagasawa T, Ikuta K, Kitoh A, and Kabashima K.
- Journal Title
  
  J. Allergy Clin. Immunol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21525
[Journal Article] Prolonged high-intensity exercise induces fluctuating immune responses to herpes simplex virus infection via glucocorticoids2021
- Author(s)
  Adachi, A., Honda, T., Dainichi, T., Egawa, G., Yamamoto, Y., Nomura, T., Nakajima, S., Otsuka, A., Maekawa, M., Mano, N., Koyanagi, N., Kawaguchi, Y., Ohteki, T., Nagasawa, T., Ikuta, K., Kitoh, A., and Kabashima, K.
- Journal Title
  
  J. Allergy Clin. Immunol.
  
  Volume: 148 Issue: 6 Pages: 1575-1588.e7
- DOI
  10.1016/j.jaci.2021.04.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20H05697, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-19K08748, KAKENHI-PROJECT-20K08689, KAKENHI-PROJECT-21K08303, KAKENHI-PROJECT-20H05692
[Journal Article] The roles of IL-7 and IL-15 in niches for lymphocyte progenitors and immune cells in lymphoid organs2021
- Author(s)
  Ikuta K, Hara T, Abe S, Asahi T, Takami D, Cui G
- Journal Title
  
  Curr. Top. Microbiol. Immunol.
  
  Volume: 434 Pages: 83-101
- DOI
  10.1007/978-3-030-86016-5_4
- ISBN
  9783030860158, 9783030860165
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07604, KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-21J15058
[Journal Article] IL-4 producing Vg1+/Vd6+ gd T cells sustain germinal center reactions in Peyer's patches of mice2021
- Author(s)
  Ullrich, L., Lueder, Y., Juergens, A.-L., Wilharm, A., Barros-Martins, J., Bubke, A., Demera, A., Ikuta, K., Patzer, G. E., Janssen, A., Sandrock, I., Prinz, I., and Rampoldi, F.
- Journal Title
  
  Front. Immunol.
  
  Volume: 12 Pages: 729607-729607
- DOI
  10.3389/fimmu.2021.729607
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20H03501
[Journal Article] Lymph node stromal cells: diverse meshwork structures weave functionally subdivided niches2021
- Author(s)
  Takeuchi, A., Ozawa, M., Cui, G., Ikuta, K., and Katakai, T.
- Journal Title
  
  Curr. Top. Microbiol. Immunol.
  
  Volume: 434 Pages: 103-121
- DOI
  10.1007/978-3-030-86016-5_5
- ISBN
  9783030860158, 9783030860165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21525, KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-21H02653, KAKENHI-PROJECT-19K07603, KAKENHI-PROJECT-19K22528
[Journal Article] Fate of adipocyte progenitors during adipogenesis in mice fed a high-fat diet2021
- Author(s)
  Bilal M, Nawaz A, Kado T, Rahil Aslam M, Igarashi Y, Nishimura A, Watanabe A, Kuwano T, Liu J, Miwa H, Era T, Ikuta K, Imura J, Yagi K, Nakagawa T, Fujisaka S, Tobe K.
- Journal Title
  
  Molecular Metabolism
  
  Volume: 54 Pages: 101328-101328
- DOI
  10.1016/j.molmet.2021.101328
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20K22733, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-20K20655
[Journal Article] Control of immunity by glucocorticoids in health and disease.2020
- Author(s)
  Shimba A. and Ikuta K.
- Journal Title
  
  Semin. Immunopathol.
  
  Volume: 42 Issue: 6 Pages: 669-680
- DOI
  10.1007/s00281-020-00827-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20K16280
[Journal Article] Glucocorticoids regulate circadian rhythm of innate and adaptive immunity.2020
- Author(s)
  Shimba A. and Ikuta K.
- Journal Title
  
  Front. Immunol.
  
  Volume: 11 Pages: 2143-2143
- DOI
  10.3389/fimmu.2020.02143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20K16280
[Journal Article] Immune-enhancing effects of glucocorticoids in response to day-night cycles and stress.2020
- Author(s)
  Shimba A. and Ikuta K.
- Journal Title
  
  Int. Immunol.
  
  Volume: 32 Issue: 11 Pages: 703-708
- DOI
  10.1093/intimm/dxaa048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20K16280
[Journal Article] Intestinal epithelial cell-derived IL-15 determines local maintenance and maturation of intra-epithelial lymphocytes in the intestine2019
- Author(s)
  Zhu Yuanbo、Cui Guangwei、Miyauchi Eiji、Nakanishi Yuki、Mukohira Hisa、Shimba Akihiro、Abe Shinya、Tani-ichi Shizue、Hara Takahiro、Nakase Hiroshi、Chiba Tsutomu、Sehara-Fujisawa Atsuko、Seno Hiroshi、Ohno Hiroshi、Ikuta Koichi
- Journal Title
  
  International Immunology
  
  Volume: 32 Issue: 5 Pages: 307-319
- DOI
  10.1093/intimm/dxz082
- NAID
  120006846480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-19K07604, KAKENHI-PROJECT-19K16687, KAKENHI-PROJECT-19K16712, KAKENHI-PROJECT-20K16280, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-18K07958
[Journal Article] Notch signaling controls transcription via the recruitment of RUNX1 and MYB to enhancers during T cell development2019
- Author(s)
  Rodriguez-Caparros, A., Garcia, V., Casal, A, Lopez-Ros, J., Garcia-Mariscal, A., Tani-ichi, S., Ikuta, K., and Hernandez-Munain, C.
- Journal Title
  
  J. Immunol.
  
  Volume: 202 Issue: 8 Pages: 2460-2472
- DOI
  10.4049/jimmunol.1801650
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05172
[Journal Article] Tissue maintenance of CMV-specific inflationary memory T cells by IL-152018
- Author(s)
  Baumann, N., Torti, N., Welten, S. P. M., Barnstorf, I., Borsa, M., Pallmer, K., Oduro, J. D., Cicin-Sain, L., Ikuta, K., Ludewig, B., and Oxenius, A.
- Journal Title
  
  PLoS Pathog.
  
  Volume: 14 Issue: 4 Pages: e1006993-e1006993
- DOI
  10.1371/journal.ppat.1006993
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05172
[Journal Article] Glucocorticoids Drive Diurnal Oscillations in T Cell Distribution and Responses by Inducing Interleukin-7 Receptor and CXCR42018
- Author(s)
  Shimba A, Cui G, Tani-Ichi S, Ogawa M, Abe S, Okazaki F, Kitano S, Miyachi H, Yamada H, Hara T, Yoshikai Y, Nagasawa T, Schütz G, Ikuta K.
- Journal Title
  
  Immunity
  
  Volume: 48 Issue: 2 Pages: 286-298
- DOI
  10.1016/j.immuni.2018.01.004
- NAID
  120006401712
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08835, KAKENHI-PLANNED-16H06496, KAKENHI-PUBLICLY-17H05643, KAKENHI-PROJECT-16H05172, KAKENHI-PROJECT-16K15288, KAKENHI-PROJECT-17K15721
[Journal Article] High fat diet exacerbates murine psoriatic dermatitis by increasing the number of IL-17-producing γδ T cells2017
- Author(s)
  Nakamizo Satoshi、Honda Tetsuya、Adachi Akimasa、Nagatake Takahiro、Kunisawa Jun、Kitoh Akihiko、Otsuka Atsushi、Dainichi Teruki、Nomura Takashi、Ginhoux Florent、Ikuta Koichi、Egawa Gyohei、Kabashima Kenji
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 999-999
- DOI
  10.1038/s41598-017-14292-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19655, KAKENHI-PROJECT-26293111, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PUBLICLY-16H01373, KAKENHI-PROJECT-16H05172, KAKENHI-PROJECT-16K15288
[Journal Article] Thy-1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation2016
- Author(s)
  Shinoda, K., Hirahara, K., Iinuma, T., Ichikawa, T., Suzuki, A., Sugaya, K., Tumes, D. J., Yamamoto, H., Hara, T., Tani-ichi, S., Ikuta, K., Okamoto, Y., and Nakayama, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: ?
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460589
[Journal Article] Fibroblastic reticular cells regulate intestinal inflammation through IL-15-mediated control of group 1 ILCs2016
- Author(s)
  Gil-Cruz, C., Perez-Shibayama, C., Onder, L., Chai, Q., Cupovic, J., Cheng, H., Novkovic, M., Lang, P. A., Geuking, M. B., McCoy, K. D., Abe, S., Cui, G., Ikuta, K., Scandella, E., and Ludewig, B.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 17 Issue: 12 Pages: 1388-1396
- DOI
  10.1038/ni.3566
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01153, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-16H05172, KAKENHI-PROJECT-15F15114, KAKENHI-PROJECT-16K15288
[Journal Article] Thy-1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation2016
- Author(s)
  Shinoda, K., Hirahara, K., Iinuma, T., Ichikawa, T., Suzuki, A. S., Sugaya, K., Tumes, D. J., Yamamoto, H., Hara, T., Tani-ichi, S., Ikuta, K., Okamoto, Y., and Nakayama, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 113 Issue: 20
- DOI
  10.1073/pnas.1512600113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01153, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H05172, KAKENHI-PROJECT-16K15288
[Journal Article] Immunosuppression caused by sepsis-induced osteoblast ablation2016
- Author(s)
  Terashima, A., Okamoto, K., Nakashima, T., Akira, S., Ikuta, K. and Takayanagi, H.
- Journal Title
  
  Immunity
  
  Volume: ?
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460589
[Journal Article] γδ T cells shape pre-immune peripheral B cell populations.2016
- Author(s)
  Huang, Y., Getahun, A., Heiser, R. A., Detanico, T. O., Kirchenbaum, G. A., Casper, T. L., Huang, C., Aydintug, M. K., Carding, S. R., Ikuta, K., Huang, H., Wysocki, L. J., Cambier, J. C., O’Brien, R. L., and Born, W. K.
- Journal Title
  
  J. Immunol.
  
  Volume: 196 Issue: 1 Pages: 217-231
- DOI
  10.4049/jimmunol.1501064
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01153, KAKENHI-PROJECT-25460589
[Journal Article] Hematopoietic stem cell niches produce lineage-instructive signals to control multipotent progenitor differentiation2016
- Author(s)
  Gomes, A. C., Hara, T., Lim, V. Y., Herndler-Brandstetter, D., Nevius, E., Sugiyama, T., Tani-ichi, S., Schlenner, S., Richie, E., Rodewald, H., Flavell, R. A., Nagasawa, T., Ikuta, K., and Pereira, J. P.
- Journal Title
  
  Immunity
  
  Volume: 45 Issue: 6 Pages: 1219-1231
- DOI
  10.1016/j.immuni.2016.11.004
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01153, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111003, KAKENHI-PROJECT-16H05172, KAKENHI-PROJECT-16K08835, KAKENHI-PROJECT-16K15288
[Journal Article] Sepsis-induced osteoblast ablation causes immunodeficiency2016
- Author(s)
  Terashima, A., Okamoto, K., Nakashima, T., Akira, S., Ikuta, K. and Takayanagi, H.
- Journal Title
  
  Immunity
  
  Volume: 44 Issue: 6 Pages: 1434-1443
- DOI
  10.1016/j.immuni.2016.05.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01153, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-16H05172, KAKENHI-PROJECT-16H05506, KAKENHI-PROJECT-15H05653, KAKENHI-PROJECT-16K15288, KAKENHI-PROJECT-15H05703
[Journal Article] Memory CD8+ T cells colocalize with IL-7+ stromal cells in bone marrow and rest in terms of proliferation and transcription2015
- Author(s)
  Alp, O. S., Durlanik, S., Schulz, D., McGrath, M., Grun, J. R., Bardua, M., Ikuta, K., Sgouroudis, E., Riedel, R., Zehentmeier, S., Hauser, A. E., Tsuneto, M., Melchers, F., Tokoyoda, K., Chang, H-D., Thiel, A., and Radbruch, A.
- Journal Title
  
  Eur. J. Immunol.
  
  Volume: 45 Issue: 4 Pages: 975-987
- DOI
  10.1002/eji.201445295
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01153, KAKENHI-PROJECT-25460589
[Journal Article] A genome-wide analysis identifies a Notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice.2015
- Author(s)
  Nakamura M, Shibata K, Hatano S, Sato T, Ohkawa Y, Yamada H, Ikuta K, Yoshikai Y.
- Journal Title
  
  J Immunol.
  
  Volume: 194 Issue: 1 Pages: 243-251
- DOI
  10.4049/jimmunol.1401619
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589
[Journal Article] Ectopic Aire expression in 1 the thymic cortex reveals inherent properties of Aire as a tolerogenic factor within the medulla2015
- Author(s)
  Nishijima H, Kitano S, Miyachi H, Morimoto J, Kawano H, Hirota F, Morita R, Mouri Y, Masuda K, Imoto I, Ikuta K, Matsumoto M.
- Journal Title
  
  J Immunol
  
  Volume: 195 Issue: 10 Pages: 4641-4649
- DOI
  10.4049/jimmunol.1501026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08949, KAKENHI-PROJECT-26460577, KAKENHI-PROJECT-26461464, KAKENHI-PUBLICLY-15H01153, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-25860363, KAKENHI-PROJECT-25293223
[Journal Article] An Enhancer of the IL-7 Receptor α-Chain Locus Controls IL-7 Receptor Expression and Maintenance of Peripheral T Cells.2015
- Author(s)
  Abe A, Tani-ichi S, Shitara S, Cui G, Yamada H, Miyachi H, Kitano S, Hara T, Abe R, Yoshikai Y, Ikuta K.
- Journal Title
  
  J. Immunol.
  
  Volume: 195 Issue: 7 Pages: 3129-3138
- DOI
  10.4049/jimmunol.1302447
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06843, KAKENHI-PUBLICLY-15H01153, KAKENHI-PROJECT-15F15114, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-26860322
[Journal Article] STAT5 Orchestrates Local Epigenetic Changes for Chromatin Accessibility and Rearrangements by Direct Binding to the TCRγ Locus.2015
- Author(s)
  Wagatsuma K, Tani-Ichi S, Liang B, Shitara S, Ishihara K, Abe M, Miyachi H, Kitano S, Hara T, Nanno M, Ishikawa H, Sakimura K, Nakao M, Kimura H, Ikuta K.
- Journal Title
  
  J Immunol.
  
  Volume: 195 Issue: 4 Pages: 1804-14
- DOI
  10.4049/jimmunol.1302456
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350979, KAKENHI-PROJECT-26460572, KAKENHI-PROJECT-15K21083, KAKENHI-PUBLICLY-15H01153, KAKENHI-PLANNED-25116005, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-26640007, KAKENHI-PROJECT-26860322
[Journal Article] γδ T cells affect IL-4 production and B cell tolerance2015
- Author(s)
  Huang, Y., Heiser, R. A., Detanico, T. O., Getahun, A., Kirchenbaum, G. A., Aydintug, M. K., Smith, C. W., Carding, S. R., Ikuta, K., Huang, H., Wysocki, L. J., Cambier, J. C., O’Brien, R. L., and Born, W. K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 112 Issue: 1
- DOI
  10.1073/pnas.1415107111
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589
[Journal Article] Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma.2015
- Author(s)
  Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, Saya H, Amagai M, Nagao K.
- Journal Title
  
  Nature Med.
  
  Volume: 21 Issue: 11 Pages: 1272-1279
- DOI
  10.1038/nm.3962
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06840, KAKENHI-PUBLICLY-15H01153, KAKENHI-PROJECT-26253065, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-15K14384
[Journal Article] Characterization of the interleukin-15 niche in primary and secondary lymphoid organs in vivo.2014
- Author(s)
  Cui G, Hara T, Simmons S, Wagatsuma K, Abe A, Miyachi H, Kitano S, Ishii M, Tani-ichi S, Ikuta K.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 111 Issue: 5 Pages: 1915-1920
- DOI
  10.1073/pnas.1318281111
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790468, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-26860322
[Journal Article] Environments of B cell development.2014
- Author(s)
  Tsuneto M, Kajikhina E, Seiler K, Reimer A, Tornack J, Bouquet C, Simmons S, Knoll M, Wolf I, Tokoyoda K, Hauser A, Hara T, Tani-Ichi S, Ikuta K, Grun J. R, Grutzkau A, Engels N, Wienands J, Yanagisawa Y, Ohnishi K , Melchers F.
- Journal Title
  
  Immunol Lett.
  
  Volume: 157 Issue: 1-2 Pages: 60-63
- DOI
  10.1016/j.imlet.2013.11.011
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589
[Journal Article] Lymphocyte-stromal cell interaction induces IL-7 expression by interferon regulatory factors.2013
- Author(s)
  Sekai M, Tani-ichi S, Yoneyama M, Fujita T, Kina T, Ikuta K.
- Journal Title
  
  Mol Immunol
  
  Volume: 54 Issue: 3-4 Pages: 378-385
- DOI
  10.1016/j.molimm.2013.01.002
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790469, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589
[Journal Article] Signal transducer and activator of transcription 3 (Stat3) contributes to T-cell homeostasis by regulating pro-survival Bcl-2 family genes.2013
- Author(s)
  Lee JK, Won C, Yi EH, Seok SH, Kim MH, Kim SJ, Chung MH, Lee HG, Ikuta K, Ye SK.
- Journal Title
  
  Immunology
  
  Volume: 140 Issue: 3 Pages: 288-300
- DOI
  10.1111/imm.12133
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589
[Journal Article] B cell progenitors and precursors change their microenvironment in fetal liver during early development.2013
- Author(s)
  Tsuneto M, Tokoyoda K, Kajikhina E, Hauser AE, Hara T, Tani-ichi S, Ikuta K, Melchers F.
- Journal Title
  
  Stem Cells
  
  Volume: 31 Issue: 12 Pages: 2800-2812
- DOI
  10.1002/stem.1421
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790468, KAKENHI-PROJECT-24790469, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589
[Journal Article] CD49b-dependent estabhshment of T helper cell memory.2013
- Author(s)
  Hanazawa, A., Hayashizaki, K.,Shinoda, K., Yagita, H., Okumura, K., Löhning, M., Hara, T., Tani-ichi, S., Ikuta, K., Eckes, B.,Radbruch, A., Tokoyoda, K, and Nakayama, T.
- Journal Title
  
  Immuno1. Cell Bio1
  
  Volume: 91 Issue: 8 Pages: 524-531
- DOI
  10.1038/icb.2013.36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J02883, KAKENHI-PROJECT-23390260, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790468, KAKENHI-PROJECT-24790469, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-25860352
[Journal Article] Interleukin-7 produced by thymic epithelial cells plays a major role in the development of thymocytes and TCRγδ+ intraepithelial lymphocytes.2013
- Author(s)
  Shitara S, Hara T, Liang B, Wagatsuma K, Zuklys S, Hollander GA, Nakase H, Chiba T, Tani-ichi S, Ikuta K.
- Journal Title
  
  J Immunol
  
  Volume: 190 Issue: 12 Pages: 6173-6179
- DOI
  10.4049/jimmunol.1202573
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790468, KAKENHI-PROJECT-24790469, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589
[Journal Article] The pre-TCR signal induces transcriptional silencing of the TCRγlocus by reducing the recruitment ofSTAT5 and Runx to transcriptional enhancers2011
- Author(s)
  Tani-ichi, S., Satake, M., and Ikuta, K.
- Journal Title
  
  Int. Immunol
  
  Volume: 23 Pages: 553-563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531
[Journal Article] The pre-TCR signal induces transcriptional silencing of the TCRγ locus by reducing the recruitment of STAT5 and Runx to transcriptional enhancers2011
- Author(s)
  Tani-ichi, S., Satake, M., Ikuta, K.
- Journal Title
  
  Int.Immunol.
  
  Volume: 23 Issue: 9 Pages: 553-563
- DOI
  10.1093/intimm/dxr055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531, KAKENHI-PROJECT-22790460
[Journal Article] Upregulated IL-7Rα expression on colitogenic memory CD4^+ T cells may participate in the development and persistence of chronic colitis2011
- Author(s)
  Shinohara, T., Nemoto, Y., Kanai, T., Kameyama, K., Okamoto, R., Tsuchiya, K., Nakamura, T., Totsuka, T., Ikuta, K., Watanabe, M.
- Journal Title
  
  Journal of Immunology
  
  Volume: 186 Pages: 2623-2632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531
[Journal Article] Accessibility control of TCR Vγregion by STAT52010
- Author(s)
  Tani-ichi, S., Lee, H.-C., Ye, S.-K., and Ikuta, K.
- Journal Title
  
  Int. Immunol
  
  Volume: 22 Issue: 8 Pages: 693-703
- DOI
  10.1093/intimm/dxq054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531, KAKENHI-PROJECT-22790460
[Journal Article] Essential role of interleukin-17A in the formation of a mycobacterial infection-induced granuloma in the lung2010
- Author(s)
  Okamoto Yoshida, Y., Umemura, M., Yahagi, A., O Brien, R.L., Ikuta, K., Kishihara, K., Hara, H., Nakae, S., Iwakura, Y., Matsuzaki, G.
- Journal Title
  
  Journal of Immunology
  
  Volume: 184 Pages: 4414-4422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531
[Journal Article] Accessibility control of TCR Vγ region by STAT52010
- Author(s)
  Tani-ichi, S., Lee, H.-C., Ye, S.-K., Ikuta, K.
- Journal Title
  
  International Immunology
  
  Volume: 22 Pages: 693-703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531
[Journal Article] Activation of the mouse T cellreceptorγenhancers by STAT52009
- Author(s)
  Tani-ichi, S., Satake, M., and Ikuta, K.
- Journal Title
  
  Int. Immunol
  
  Volume: 21 Issue: 9 Pages: 1079-1088
- DOI
  10.1093/intimm/dxp073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590531
[Journal Article] Transcriptional activation of mouse TCR Jγ4 germline promoter by STAT52008
- Author(s)
  Masui, N., Tani-ichi, Maki, K., Ikuta, K
- Journal Title
  
  Molecular Immunology 45(3)
  
  Pages: 849-855
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580309
[Journal Article] Transcriptional activation of mouse TCR Jγ 4 germline promoter by STAT5.2008
- Author(s)
  Masui, N., Tani-ichi, Maki, K., and Ikuta, K
- Journal Title
  
  Molecular Immunology 45
  
  Pages: 849-855
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580309
[Journal Article] Transcriptional activation of mouse TCR Jγ 4 germline promoter by ST AT5.2008
- Author(s)
  Masui, N., Tani-ichi, Maki, K., and Ikuta, K
- Journal Title
  
  Molecular Immunology 45
  
  Pages: 849-855
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580309
[Journal Article] Induction of the IL-7 receptor α chain in mouse peripheral B cells by glucocorticoids2007
- Author(s)
  Shibata, H., Tani-ichi, S., Lee, H.-C., Maki, K., and Ikuta, K.
- Journal Title
  
  Immunology letter 111
  
  Pages: 45-50
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580309
[Journal Article] Induction of the IL-7 receptor a chain in mouse peripheral B cells by glucocorticoids2007
- Author(s)
  Shibata, H., Tani-ichi, S., Lee, H. -C., Maki, K., and Ikuta, K.
- Journal Title
  
  Immunology letter 111
  
  Pages: 45-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580309
[Journal Article] Induction of the IL-7 receptor a chain in mouse peripheral B cells by glucocorticoids2007
- Author(s)
  Shibata, H., Tani-ichi, S., Lee, H.C., Maki, K., Ikuta, K
- Journal Title
  
  Immunology letter 111(1)
  
  Pages: 45-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580309
[Journal Article] Induction of the IL-7 receptor α chain in mouse peripheral B cells by glucocorticoids
- Author(s)
  Shibata, H., Tani-ichi, S., Lee, H.-C., Maki, K., Ikuta, K.
- Journal Title
  
  Immunology letter (印刷中)
- Data Source
  KAKENHI-PROJECT-18580309
[Presentation] 新規末梢循環型iNKT細胞の同定と機能解析2022
- Author(s)
  崔広為、生田宏一
- Organizer
  Kyoto T Cell Conference 第31回学術集会
- Data Source
  KAKENHI-PROJECT-20H03501
[Presentation] Lung local IL-7 affect the maintenance, distribution, and activation of ILC2 in allergic airway inflammations2022
- Author(s)
  Daichi Takami, Shinya Abe, Akihiro Shimba, Takuma Asahi, Guangwei Cui, Shizue Tani-ichi, Takahiro Hara, and Koichi Ikuta
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03501
[Presentation] Hepatic ILC1s lacking IL-7 receptor arise independently of conventional group 1 ILCs through parenchymal niches2022
- Author(s)
  Takuma Asahi, and Koichi Ikuta
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03501
[Presentation] 胎児肝臓に由来する1型自然リンパ球の同定2021
- Author(s)
  旭拓真、阿部真也、崔広為、榛葉旭恒、生田宏一
- Organizer
  Kyoto T Cell Conference 第30回学術集会
- Data Source
  KAKENHI-PROJECT-20H03501
[Presentation] ストレスはグルココルチコイドを介してTh17細胞の分化を促進し腸炎を増悪させる2021
- Author(s)
  榛葉旭恒、生田宏一
- Organizer
  Kyoto T Cell Conference 第30回学術集会
- Data Source
  KAKENHI-PROJECT-20H03501
[Presentation] ステロイドホルモンによる免疫機能とアレルギーの制御2021
- Author(s)
  生田宏一、榛葉旭恒、江島亜希
- Organizer
  日本アレルギー学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03501
[Presentation] ステロイドホルモンによる免疫機能とアレルギーの制御2021
- Author(s)
  生田宏一、榛葉旭恒、江島亜希
- Organizer
  日本アレルギー学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21525
[Presentation] ストレスはグルココルチコイドを介してTh17細胞の分化を促進し腸炎を増悪させる2021
- Author(s)
  榛葉旭恒、生田宏一
- Organizer
  Kyoto T Cell Conference 第30回学術集会
- Data Source
  KAKENHI-PROJECT-20K21525
[Presentation] 胎児肝臓に由来する1型自然リンパ球の同定2021
- Author(s)
  旭拓真、阿部真也、崔広為、榛葉旭恒、生田宏一
- Organizer
  Kyoto T Cell Conference 第30回学術集会
- Data Source
  KAKENHI-PROJECT-20K21525
[Presentation] Intestinal epithelial cell-derived IL-15 supports the homeostasis of intraepithelial lymphocytes2018
- Author(s)
  Zhu, Y., Cui, G., Shimba, A., Abe, S., Hara, T., Tani-ichi, S., and Ikuta, K.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Hematopoietic cell-derived IL-15 supports the development and maintenance of NK, NKT and memory CD8 T cells in bone marrow2018
- Author(s)
  Abe, S., Hara, T., Cui, G., Asahi, T., and Ikuta, K.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Local IL-15 dependency of liver-resident ILC12018
- Author(s)
  Asahi, T., Shimba, A., Cui, G., Abe, S., Zhu, Y., Ejima, A., Takami, D., Tani-ichi, S., Hara, T., and Ikuta, K.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Intestinal epithelial cell-derived IL-15 supports the homeostasis of intraepithelial lymphocytes2018
- Author(s)
  Zhu, Y., Cui, G., and Ikuta, K.
- Organizer
  The 25th East Asia Joint Symposium on Biomedical Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] CXCL12-expressing bone marrow stromal cells express adiponectin and are targeted by Adipoq-Cre transgene2018
- Author(s)
  Mukohira, H., Hara, T., Tani-ichi, S., and Ikuta, K.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] 胸腺内IL-15産生性免疫微小環境の機能解析2018
- Author(s)
  崔広為、生田宏一
- Organizer
  Kyoto T Cell Conference 第28回学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] IL-7Rα signaling upregulates growth hormone signaling-related gene in naive T cells2017
- Author(s)
  Tani-ichi, S., and Ikuta, K.
- Organizer
  Keystone Symposium: Integrating Metabolism and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Exploring the signals upregulating IL-7Rα expression via NFκB activation in T cells2017
- Author(s)
  Tani-ichi, S., and Ikuta, K.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Osteoblasts mediate immunosuppression during sepsis by regulating lymphopoiesis2017
- Author(s)
  Terashima, A., Okamoto, K., Nakashima, T., Ikuta, K., and Takayanagi, H.
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] グルココルチコイドはIL-7受容体の発現を介してT細胞の体内分布および活性化の日内変動を制御する2017
- Author(s)
  岡崎史恵、榛葉旭恒、崔広為、生田宏一
- Organizer
  ConBio2017（生命科学系学会合同年次大会）
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Exploring the signals upregulating IL-7Rα expression via NFκB activation in T cells2017
- Author(s)
  Tani-ichi, S., and Ikuta, K.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] グルココルチコイドはIL-7受容体の発現を介してT細胞の体内分布および活性化の日内変動を制御する2017
- Author(s)
  岡崎史恵、榛葉旭恒、崔広為、生田宏一
- Organizer
  ConBio2017（生命科学系学会合同年次大会）
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] Regulation of IL-7 receptor expression by a proximal enhancer2017
- Author(s)
  榛葉旭恒、崔広為、谷一靖江、原崇裕、生田宏一
- Organizer
  KTCC 2017
- Place of Presentation
  芝蘭会館、京都
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] Competition between STAT5 and PI3K of the IL-7R modulates T cell and type 2 ILC development in vivo2017
- Author(s)
  Cui, G., Shimba, A., Zhu, Y., Tani-ichi, S., Hara, T., and Ikuta, K.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Glucocorticoids drive circadian changes in T-cell homing and response via IL-7 receptor2017
- Author(s)
  Shimba, A., and Ikuta, K.
- Organizer
  Immunology 2017 (AAI)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] Glucocorticoids drive diurnal changes in distribution and response of T cells via IL-7 receptor expression2017
- Author(s)
  Shimba, A., Cui, G., and Ikuta, K.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Glucocorticoids drive diurnal changes in distribution and response of T cells via IL-7 receptor expression2017
- Author(s)
  Shimba, A., Cui, G., and Ikuta, K.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] Competition between STAT5 and PI3K of the IL-7R modulates T cell and type 2 ILC development in vivo2017
- Author(s)
  Cui, G., Shimba, A., Zhu, Y., Tani-ichi, S., Hara, T., and Ikuta, K.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] Osteoblasts mediate immunosuppression during sepsis by regulating lymphopoiesis2017
- Author(s)
  Terashima, A., Okamoto, K., Nakashima, T., Ikuta, K., and Takayanagi, H.
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] IL-7Rα signaling upregulates growth hormone signaling-related gene in naive T cells2017
- Author(s)
  Tani-ichi, S., and Ikuta, K.
- Organizer
  Keystone Symposium: Integrating Metabolism and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] Glucocorticoids drive circadian changes in T-cell homing and response via IL-7 receptor2017
- Author(s)
  Shimba, A., and Ikuta, K.
- Organizer
  Immunology 2017 (AAI)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Identification of bone marrow IL-7 niche critical for B lymphopoesis2017
- Author(s)
  原崇裕、生田宏一
- Organizer
  The 7th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  芝蘭会館、京都市
- Year and Date
  2017-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Identification of bone marrow IL-7 niche critical for B lymphopoesis2017
- Author(s)
  原崇裕、生田宏一
- Organizer
  The 7th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  芝蘭会館、京都市
- Year and Date
  2017-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01153
[Presentation] Role of glucocorticoids in T cell homeostasis and T cell response2016
- Author(s)
  榛葉旭恒、崔広為、阿部真也、朱媛博、向平妃沙、谷一靖江、原崇裕、生田宏一
- Organizer
  The 23rd East Asia Joint Symposium
- Place of Presentation
  台北、台湾
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15288
[Presentation] Local function of the IL-15 niche in thymus2016
- Author(s)
  崔広為、榛葉旭恒、阿部真也、朱媛博、向平妃沙、谷一靖江、原崇裕、生田宏一
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター、宜野湾市、沖縄
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Local function of the IL-15 niche in thymus2016
- Author(s)
  崔広為、榛葉旭恒、阿部真也、朱媛博、向平妃沙、谷一靖江、原崇裕、生田宏一
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター、宜野湾市、沖縄
- Data Source
  KAKENHI-PUBLICLY-15H01153
[Presentation] Immunodeficiency caused by sepsis-induced osteoblast ablation2016
- Author(s)
  寺島明日香、岡本一男、審良静男、生田宏一、高柳広
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター、宜野湾市、沖縄
- Data Source
  KAKENHI-PUBLICLY-15H01153
[Presentation] 骨髄におけるリンパ球分化を制御するIL-7産生ストローマ細胞の同定2016
- Author(s)
  原崇裕、生田宏一
- Organizer
  第26回Kyoto T Cell Conference
- Place of Presentation
  延暦寺会館、大津市
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] 骨髄におけるリンパ球分化を制御するIL-7産生ストローマ細胞の同定2016
- Author(s)
  原崇裕、生田宏一
- Organizer
  第26回Kyoto T Cell Conference
- Place of Presentation
  延暦寺会館、大津市
- Data Source
  KAKENHI-PUBLICLY-15H01153
[Presentation] Identification of IL-15 niche for NK cells in bone marrow2016
- Author(s)
  阿部真也、原崇裕、崔広為、生田宏一
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  宜野湾市、沖縄県
- Data Source
  KAKENHI-PROJECT-15F15114
[Presentation] Identification of IL-15 niche for NK cells in bone marrow2016
- Author(s)
  阿部真也、原崇裕、崔広為、生田宏一
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター、宜野湾市、沖縄
- Data Source
  KAKENHI-PUBLICLY-15H01153
[Presentation] Local function of the IL-15 niche in thymus2016
- Author(s)
  崔広為、榛葉旭恒、阿部真也、朱媛博、向平妃沙、谷一靖江、原崇裕、生田宏一
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  宜野湾市、沖縄県
- Data Source
  KAKENHI-PROJECT-15F15114
[Presentation] Identification of IL-15 niche for NK cells in bone marrow2016
- Author(s)
  阿部真也、原崇裕、崔広為、生田宏一
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター、宜野湾市、沖縄
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Immunodeficiency caused by sepsis-induced osteoblast ablation2016
- Author(s)
  寺島明日香、岡本一男、審良静男、生田宏一、高柳広
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター、宜野湾市、沖縄
- Data Source
  KAKENHI-PROJECT-16H05172
[Presentation] Characterization of the IL-15 niche in vivo2015
- Author(s)
  Cui, G., Hara, T., Simmons, S., Ishii, M., Tani-ichi, S., Ikuta, K.
- Organizer
  The 6th FIMSA Congress
- Place of Presentation
  Singapore
- Year and Date
  2015-07-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Regulation of IL-7R expression in dendritic cells2015
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Characterization of the IL-15 niche in vivo2015
- Author(s)
  Cui, G., Hara, T., Simmons, S., Ishii, M., Tani-ichi, S., Ikuta, K.
- Organizer
  The 6th FIMSA Congress
- Place of Presentation
  Singapore
- Year and Date
  2015-07-01
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01153
[Presentation] Identification and characterization of IL-7 niche in gut-associated lymphoid tissue2015
- Author(s)
  原崇裕、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PUBLICLY-15H01153
[Presentation] Differential roles of IL-7 and IL-2 receptor signals in lymphocyte differentiation and development revealed by IL-7Rα/IL-2Rβ chimera knock-in mice2015
- Author(s)
  榛葉旭恒、谷一靖江、増田喬子、崔広為、小川真、阿部真也、原崇裕、河本宏、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15F15114
[Presentation] STAT5 and PI3K signals of the IL-7R play differential roles in T cell development and homeostasis revealed by novel IL-7Rα mutant mice2015
- Author(s)
  崔広為、榛葉旭恒、谷一靖江、小川真、阿部真也、原崇裕、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PUBLICLY-15H01153
[Presentation] STAT5 and PI3K signals of the IL-7R play differential roles in T cell development and homeostasis revealed by novel IL-7Rα mutant mice2015
- Author(s)
  崔広為、榛葉旭恒、谷一靖江、小川真、阿部真也、原崇裕、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Regulation of IL-7R expression in dendritic cells2015
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01153
[Presentation] Characterization of the IL-15 niche in vivo2015
- Author(s)
  Cui, G., Hara, T., Simmons, S., Ishii, M., Tani-ichi, S., Ikuta, K.
- Organizer
  The 6th FIMSA Congress
- Place of Presentation
  Singapore
- Year and Date
  2015-07-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15F15114
[Presentation] STAT5 and PI3K signals of the IL-7R play differential roles in T cell development and homeostasis revealed by novel IL-7Rα mutant mice2015
- Author(s)
  崔広為、榛葉旭恒、谷一靖江、小川真、阿部真也、原崇裕、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15F15114
[Presentation] Identification and characterization of IL-7 niche in gut-associated lymphoid tissue2015
- Author(s)
  原崇裕、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Differential roles of IL-7 and IL-2 receptor signals in lymphocyte differentiation and development revealed by IL-7Rα/IL-2Rβ chimera knock-in mice2015
- Author(s)
  榛葉旭恒、谷一靖江、増田喬子、崔広為、小川真、阿部真也、原崇裕、河本宏、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Differential roles of IL-7 and IL-2 receptor signals in lymphocyte differentiation and development revealed by IL-7Rα/IL-2Rβ chimera knock-in mice2015
- Author(s)
  榛葉旭恒、谷一靖江、増田喬子、崔広為、小川真、阿部真也、原崇裕、河本宏、生田宏一
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PUBLICLY-15H01153
[Presentation] Differential roles of IL-7 and IL-2 receptor signals in lymphocyte development and maintenance revealed by IL-7Rα/IL-2Rβ chimera knock-in mice2014
- Author(s)
  榛葉旭恒、谷一靖江、増田喬子、原崇裕、河本宏、生田宏一
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PUBLICLY-25111504
[Presentation] 末梢組織でのガンマデルタT細胞維持におけるTCRシグナルの必要性2014
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第24回Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Distribution and function of IL-7- and IL-15-expressing cells in intestines2014
- Author(s)
  原崇裕、崔広為、生田宏一
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PUBLICLY-25111504
[Presentation] Differential roles of IL-7 and IL-2 receptor signals in lymphocyte development and maintenance revealed by IL-7Rα/IL-2Rβ chimera knock-in mice2014
- Author(s)
  榛葉旭恒、谷一靖江、増田喬子、原崇裕、河本宏、生田宏一
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] 末梢組織でのガンマデルタT細胞維持におけるTCRシグナルの必要性2014
- Author(s)
  谷一靖江、生田宏一
- Organizer
  第24回Kyoto T Cell Conference
- Place of Presentation
  京都
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PUBLICLY-25111504
[Presentation] Distribution and function of IL-7- and IL-15-expressing cells in intestines2014
- Author(s)
  原崇裕、崔広為、生田宏一
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Approaches to identify Aire-regulated non-tissue-restricted antigen genes by the ectopic expression of Aire in thymic cortex2014
- Author(s)
  西嶋仁、森本純子、毛利安宏、河野弘、生田宏一、松本満
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Approaches to identify Aire-regulated non-tissue-restricted antigen genes by the ectopic expression of Aire in thymic cortex2014
- Author(s)
  西嶋仁、森本純子、毛利安宏、河野弘、生田宏一、松本満
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PUBLICLY-25111504
[Presentation] Visualizing the immune microenvironment by reporter mice2013
- Author(s)
  Ikuta, K., Cui, G., Shitara, S., Liang, B., Tani-ichi, S., and Hara, T.
- Organizer
  The 20th East Asia Joint Symposium on Global Medical Science for the 22th Century
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Identification and characterization of the IL-15-expressing cells in vivo2013
- Author(s)
  Cui, G., Hara, T., Simmons, S., Wagatsuma, K., Tani-ichi, S., Ishii, M., and Ikuta, K.
- Organizer
  The 20th East Asia Joint Symposium on Global Medical Science for the 22th Century
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PUBLICLY-25111504
[Presentation] Distribution and function of IL-7-expressing cells in large intestine2013
- Author(s)
  Hara, T. and Ikuta, K.
- Organizer
  The 4th Workshop on Synthetic Immunology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PUBLICLY-25111504
[Presentation] Visualization and characterization of IL-7- and IL-15-expressing cells in vivo2013
- Author(s)
  Hara, T., Cui, G., Shitara, S., Tani-ichi, S. and Ikuta, K.
- Organizer
  The 6th International Workshop of Kyoto T Cell Conference 2013
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PUBLICLY-25111504
[Presentation] Distribution and function of IL-7-expressing cells in the intestinal tissues2013
- Author(s)
  Hara, T. and Ikuta, K.
- Organizer
  The 8th International Symposium of the Institute Network
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Visualization of the immune microenvironment by reporter mice2013
- Author(s)
  Ikuta, K., Cui, G., Shitara, S., Liang, B., Tani-ichi, S., and Hara, T.
- Organizer
  The 6th International Workshop of Kyoto T Cell Conference 2013
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Visualization of the immune microenvironment by reporter mice2013
- Author(s)
  Ikuta, K., Cui, G., Shitara, S., Liang, B., Tani-ichi, S., and Hara, T.
- Organizer
  The 6th International Workshop of Kyoto T Cell Conference 2013
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PUBLICLY-25111504
[Presentation] Distribution and function of IL-7-expressing cells in intestines2013
- Author(s)
  原崇裕、崔広為、設楽宗一朗、生田宏一
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PUBLICLY-25111504
[Presentation] Distribution and function of IL-7-expressing cells in large intestine2013
- Author(s)
  Hara, T. and Ikuta, K.
- Organizer
  The 4th Workshop on Synthetic Immunology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Visualizing the immune microenvironment by reporter mice2013
- Author(s)
  Ikuta, K., Cui, G., Shitara, S., Liang, B., Tani-ichi, S., and Hara, T.
- Organizer
  The 20th East Asia Joint Symposium on Global Medical Science for the 22th Century
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PUBLICLY-25111504
[Presentation] Visualization and characterization of IL-7- and IL-15-expressing cells in vivo2013
- Author(s)
  Hara, T., Cui, G., Shitara, S., Tani-ichi, S. and Ikuta, K.
- Organizer
  The 6th International Workshop of Kyoto T Cell Conference 2013
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Distribution and function of IL-7-expressing cells in intestines2013
- Author(s)
  原崇裕、崔広為、設楽宗一朗、生田宏一
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] Distribution and function of IL-7-expressing cells in the intestinal tissues2013
- Author(s)
  Hara, T. and Ikuta, K.
- Organizer
  The 8th International Symposium of the Institute Network
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PUBLICLY-25111504
[Presentation] Identification and characterization of the IL-15-expressing cells in vivo2013
- Author(s)
  Cui, G., Hara, T., Simmons, S., Wagatsuma, K., Tani-ichi, S., Ishii, M., and Ikuta, K.
- Organizer
  The 20th East Asia Joint Symposium on Global Medical Science for the 22th Century
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-25460589
[Presentation] リンパ管内皮細胞が産生するIL-7は末梢T細胞の組織分布を制御する2011
- Author(s)
  原崇裕、生田宏一
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] 腸管上皮内γ δ T細胞は胸腺に由来する2011
- Author(s)
  設楽宗一朗、梁冰霏、原崇裕、我妻慶祐、生田宏一
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] 肝細胞が産生するIL-7は肝臓でのリンパ球の分化と維持を制御する2011
- Author(s)
  梁冰霏、原崇裕、我妻慶祐、設楽宗一朗、谷一靖江、生田宏一
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] 腸管上皮内γδT細胞は胸腺に由来する2011
- Author(s)
  設楽宗一朗、梁冰霏、原崇裕、我妻慶祐、生田宏一
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] Local function of IL-7 produced by thymic and epidermal epithelial cells2010
- Author(s)
  Liang, B., Hara, T., Tani-ichi, S., Ikuta, K.
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] Local function of IL-7produced by thymic and epidermal epithelial cells2010
- Author(s)
  Liang, B., Hara, T., Tani-ichi, S., and Ikuta, K.
- Organizer
  The 14^<th> International Congress of Immunology
- Place of Presentation
  Kobe
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] Distribution of IL-7-expressing cells in lymphoid organs2010
- Author(s)
  Hara, T., Tani-ichi, S., Ikuta, K.
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] Distribution of IL-7-expressing organs. International Congress of Immunology2010
- Author(s)
  Hara, T., Tani-ichi, S., and Ikuta, K
- Organizer
  The 14^<th> International Congress of Immunology
- Place of Presentation
  Kobe
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] リンパ組織におけるIL-7産生細胞の分布と機能2009
- Author(s)
  生田宏一、原崇裕、梁冰霏、谷一靖江
- Organizer
  第32回日本分子生物学会年会ワークショップ
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] 胸線上皮細胞が産生するIL-7の局所的役割2009
- Author(s)
  生田宏一、原崇裕、梁冰霏、谷一靖江
- Organizer
  第39回日本免疫学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] リンパ組織におけるIL-7産生細胞の分布と機能2009
- Author(s)
  生田宏一、原崇裕、梁冰霏、谷一靖江
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21590531
[Presentation] MEK1/2 controls the accessibility of the TCRγ Locus in IL-7R signaling2006
- Author(s)
  Maki, K., Hayashi, S., Ikuta, K
- Organizer
  The 36th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Osaka
- Year and Date
  2006-12-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580309
[Presentation] The IL-7 Receptor Controls the Accessibility of the TCRγ Locus by MAPK Pathway2006
- Author(s)
  Maki, K., Hayashi, S., Ikuta, K
- Organizer
  20th International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580309
[Presentation] IL-7RシグナルによるMEKを介したTCRγ遺伝子座のV-J組換え制御機構の解析2006
- Author(s)
  真木一茂、生田宏一
- Organizer
  第36回日本免疫学会
- Place of Presentation
  大阪(大阪国際会議場)
- Year and Date
  2006-12-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580309
[Presentation] The IL-7 Receptor Controls the Accessibility of the TCRγ Locus by MAPK Pathway2006
- Author(s)
  Maki, K., Hayashi, S and Ikuta, K
- Organizer
  20th International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  京都(京都国際会館)
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580309

1. UEDA Masamichi (50115797)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. MAKI Kazushige (10311424)

# of Collaborated Projects: 7 results

# of Collaborated Products: 11 results
3. TANI-ICHI Shizue (50432331)

# of Collaborated Projects: 6 results

# of Collaborated Products: 41 results
4. YE Sang-kyu

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. 宮崎純一 (10200156)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 榛葉旭恒 (30812242)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
7. HAYASHI Satoko (60402806)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HARA Takahiro (90512301)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
9. 崔广為 (70791276)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
10. CUI Guangwei

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
11. 李海天

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. TANIGUCHI Yoshihito (00324616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KUROOKA Hisanori (00293879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KINOSHITA Kazuo (50293874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KAKAZU Naoki (20264757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. AKAMIZU Takashi (20231813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 田代文 (40136213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 小澤敬也 (30137707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 吉田進昭 (10250341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 北村俊雄 (20282527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 谷憲三朗 (00183864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 竹田潤二 (50163407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 烏山一 (60195013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 反町典子 (30217468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 塚田聡 (60273637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 戸邉一之 (30251242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 瀧川章子 (80647454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 阿部真也 (70972678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. IMAI Kumiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. MUKOHIRA Hisa

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
31. Zhu Yuanbo

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
32. OGAWA Makoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 橋本主税

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. EGAWA Gyohei

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
35. YAGI Kunimasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. NAGASAWA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 宮内栄治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 増田清士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 山田真太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 安部良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 阿部学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 杉原英志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ikuta Koichi 生田 宏一

IKUTA Koichi 生田 宏一

Research Projects

Research Products

Co-Researchers

The mechanism how adipose tissue M2 macrophages regulate insulin sensitivity

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Control of immune response and tissue homeostasis by novel IL-15-dependent innate lymphocytesPrincipal Investigator

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Induction of autoimmune diseases by glucocorticoidsPrincipal Investigator

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IL-15-producing microenvironment supporting innate lymphoid cells and its role in diseasesPrincipal Investigator

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Control of innate immune cells, chronic inflammation and infection by cytokine-producing immune microenvironmentPrincipal Investigator

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Control of dynamics and function of T cells by glucocorticoids via IL-7 receptor expressionPrincipal Investigator

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サイトカイン産生性免疫微小環境の機能解析Principal Investigator

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ＩＬ－１５産生性ストローマ細胞の局所機能の解明Principal Investigator

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サイトカイン産生性免疫微小環境の可視化と機能解析Principal Investigator

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Review Section

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Distribution and function of IL-15-producing cells in vivoPrincipal Investigator

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Distribution and function of IL-7-producing cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Analysis of IL-7 receptor and application for biological protection

Principal Investigator

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Research Institution

IL-7レセプターの発現制御による免疫監視システムの形成と維持機構Principal Investigator

Principal Investigator

Project Period (FY)

Ikuta Koichi 生田宏一

IKUTA Koichi 生田宏一