NAKANO ATSUSHI 中野厚史

… Alternative Names

NAKANO Atsushi 中野厚史

中野厚史ナカノアツシ

Less

Researcher Number	90217787
Other IDs
External Links
Affiliation (Current)	2025: 国立研究開発法人国立循環器病研究センター, 研究所, 非常勤研究員
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人国立循環器病研究センター, 研究所, 非常勤研究員 2018: 国立研究開発法人国立循環器病研究センター, 研究所, 上級研究員 2017 – 2018: 国立研究開発法人国立循環器病研究センター, 研究所, 研究員 2015 – 2016: 国立研究開発法人国立循環器病研究センター, 研究所, 上級研究員 2012 – 2014: 独立行政法人国立循環器病研究センター, 研究所, 研究員 … More 2005: 国立循環器病センター(研究所), 脈管生理部, 室員 2005: National Cardiovascular Center Research Institute, Department of Vascular Physiology, Research Staff, 脈管生理部, 室長 2004: 国立循環器病センター研究所, 脈管生理部, 室員 1995 – 2002: 国立循環器病センター研究所, 脈管生理部, 室員 Less
Review Section/Research Field	Principal Investigator Fluid engineering / Basic Section 48030:Pharmacology-related / Biomedical engineering/Biomaterial science and engineering / 医学物理学・放射線技術学 Except Principal Investigator General pharmacology
Keywords	Principal Investigator 動脈硬化 / 非定常流 / 間欠流 / 血流 / データ収集 / 乱流 / 酸化LDL / 乱流遷移 / 振動流 / 統計解析 … More / 大動脈 / nanoSPECT / 褐色脂肪細胞 / バイオイメージング / 運動負荷 / 褐色脂肪 / 骨格筋 / 画像診断 / 画像解析 / SPECT / 褐色脂肪組織 / RI標識法 / 小動物イメージング / 瞬時スペクトル解析 / 数値シュミレーション / 非定常流れ / 大動脈内血流 / 時変スペクトル解析 / 乱流渦カスケード / 非定常乱流 / DNS / 直接数値シュミュレーション / 大動脈血流 / 血流乱流 / 瞬時周波数 / データ処理 / スペクトル解析 / データ解析 … More Except Principal Investigator LOX-1 / intimal thickening / arteriosclerosis / endothelial cells / oxidized LDL / oxidized LDL receptor / 内膜増殖 / 動脈硬化 / 血管内皮細胞 / 酸化LDL / 酸化LDL受容体 Less

単一心筋細胞のエネルギー効率計測法の確立と新規心不全薬探索Principal Investigator
- Principal Investigator
  
  中野厚史
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  National Cardiovascular Center Research Institute
Elucidation of a new mechanism involved in the pathogenesis of atherosclerosis based on the oxLDL kinetic imagingPrincipal Investigator
- Principal Investigator
  
  Nakano Atsushi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Cardiovascular Center Research Institute
Whole body imaging of 123I-oxLDL distribution in mouse with high resolution SPECT systemPrincipal Investigator
- Principal Investigator
  
  NAKANO Atsushi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医学物理学・放射線技術学
- Research Institution
  National Cardiovascular Center Research Institute
STUDY ON THE SIGNIFICANCE OF LOX-1 IN OXIDATIVE STRESS-RELATED BIOLOGICAL RESPONSES
- Principal Investigator
  
  SAWAMURA Tatsuya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  National Cardiovascular Center Research Institute
大動脈モデル流れ場における乱流遷移構造の解明Principal Investigator
- Principal Investigator
  
  中野厚史
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Fluid engineering
- Research Institution
  National Cardiovascular Center Research Institute
大動脈血流に生じる乱流遷移構造の解明Principal Investigator
- Principal Investigator
  
  中野厚史
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Fluid engineering
- Research Institution
  National Cardiovascular Center Research Institute
周期的間欠流に発生する乱流の時空間的構造の解明Principal Investigator
- Principal Investigator
  
  中野厚史
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Fluid engineering
- Research Institution
  National Cardiovascular Center Research Institute
周期的間欠流に発生する乱流構造の解明Principal Investigator
- Principal Investigator
  
  中野厚史
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Fluid engineering
- Research Institution
  National Cardiovascular Center Research Institute
周期的間欠流に発生する乱流構造の解明Principal Investigator
- Principal Investigator
  
  中野厚史
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Fluid engineering
- Research Institution
  National Cardiovascular Center Research Institute

All 2018 2017 2016 2015 2013 2012 Other

All Journal Article Presentation

[Journal Article] 123I-Labeled oxLDL Is Widely Distributed Throughout the Whole Body in Mice2017
- Author(s)
  Nakano Atushi、Kawashima Hidekazu、Miyake Yoshinori、Zeniya Tsutomu、Yamamoto Akihide、Koshino Kazuhiro、Temma Takashi、Fukuda Tetsuya、Fujita Yoshiko、Kakino Akemi、Kanaya Shigehiko、Sawamura Tatsuya、Iida Hidehiro
- Journal Title
  
  Nuclear Medicine and Molecular Imaging
  
  Volume: 52 Issue: 2 Pages: 144-153
- DOI
  10.1007/s13139-017-0497-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01309, KAKENHI-PROJECT-17K19670, KAKENHI-PROJECT-26350558
[Journal Article] Lectin-like oxidized low density lipoprotein receptor 1-deficient mice show resistance to instability-induced osteoarthritis2016
- Author(s)
  K Hashimoto, S Mori, Y Oda, A Nakano, T Sawamura & M Akagi
- Journal Title
  
  Scand J Rheumatol
  
  Volume: 2 Issue: 5 Pages: 1-11
- DOI
  10.3109/03009742.2015.1135979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01309, KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-16K10923
[Journal Article] Developmental Endothelial Locus-1 (Del-1) Inhibits Oxidized Low-Density Lipoprotein Activity by Direct Binding, and Its Overexpression Attenuates Atherogenesis in Mice2016
- Author(s)
  Akemi Kakino, Yoshiko Fujita, Atsushi Nakano, Sayaka Horiuchi, Tatsuya Sawamura
- Journal Title
  
  Circ J
  
  Volume: 80 Issue: 12 Pages: 2541-2549
- DOI
  10.1253/circj.CJ-16-0808
- NAID
  130005284982
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K01309, KAKENHI-PROJECT-16K19192
[Journal Article] Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor.2015
- Author(s)
  Yamamoto K, Kakino A, Takeshita H, Hayashi N, Li L, Nakano A, Hanasaki-Yamamoto H, Fujita Y, Imaizumi Y, Toyama-Yokoyama S, Nakama C, Kawai T, Takeda M, Hongyo K, Oguro R, Maekawa Y, Itoh N, Takami Y, Onishi M, Takeya Y, Sugimoto K, Kamide K, Nakagami H, Ohishi M, Kurtz TW, Sawamura T and Rakugi H.
- Journal Title
  
  The FASEB Journal
  
  Volume: Apr 15 Issue: 8 Pages: 3342-3356
- DOI
  10.1096/fj.15-271627
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24601021, KAKENHI-PROJECT-15K01309, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25670133, KAKENHI-PROJECT-25293063
[Presentation] New findings on oxLDL metabolism using in vivo imaging2018
- Author(s)
  中野厚史
- Organizer
  第23回アディポサイエンス・シンポジウム
- Data Source
  KAKENHI-PROJECT-15K01309
[Presentation] マウス全身イメージングで明らかになってきた、酸化LDLの新たな代謝経路2018
- Author(s)
  中野厚史
- Organizer
  第14回小動物インビボイメージング研究会
- Data Source
  KAKENHI-PROJECT-15K01309
[Presentation] 健常マウスにおける酸化LDLの体内動態に関する検討：I-123標識体を用いた評価2017
- Author(s)
  河嶋秀和, 中野厚史, 三宅義徳, 銭谷勉, 越野一博, 山本明秀, 垣野明美, 藤田佳子, 天滿敬, 沢村達也, 飯田秀博
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K01309
[Presentation] Imaging and evaluation of brown adipose tissue using 123I-oxLDL2017
- Author(s)
  中野厚史
- Organizer
  第22回アディポサイエンス・シンポジウム
- Data Source
  KAKENHI-PROJECT-15K01309
[Presentation] 123I 標識酸化 LDL による褐色細胞機能評価の可能性2016
- Author(s)
  中野厚史, 河嶋秀和, 天滿敬, 銭谷勉, 飯田秀博, 沢村達也
- Organizer
  第 16 回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都市勧業館「みやこめっせ」
- Year and Date
  2016-10-01
- Data Source
  KAKENHI-PROJECT-15K01309
[Presentation] 高解像度SPECT を用いたマウス酸化LDL全身分布イメージング2015
- Author(s)
  中野厚史、銭谷勉、河嶋秀和、飯田秀博、沢村達也
- Organizer
  第 10 回日本分子イメージング学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15K01309
[Presentation] Whole body imaging of 123I-oxLDL distribution in mouse with high resolution SPECT system2015
- Author(s)
  Nakano A, Zeniya T, Kawashima H, Iida H, Sawamura T
- Organizer
  JSMI 2015
- Place of Presentation
  東京
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K01309
[Presentation] 放射性ヨウ素標識酸化 LDL（123I-oxLDL）の開発と動脈硬化病変への集積に関する基礎的検討2013
- Author(s)
  河嶋秀和、中野厚史、銭谷勉、垣野明美、三宅義徳、沢村達也、飯田秀博
- Organizer
  日本分子イメージング学会　第8回学会総会・学術集会/JSMI 2013
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24601021
[Presentation] 123I-oxLDLのマウス全身動態に関する研究2013
- Author(s)
  中野厚史、河嶋秀和、三宅義徳、沢村達也、飯田秀博
- Organizer
  日本機械学会　第25回バイオエンジニアリング講演会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-24601021
[Presentation] Synthesis and evaluation of iodine-123 labeled oxidized low-density lipoprotein (123I-oxLDL) as a non-invasive imaging probe for vascular disease2012
- Author(s)
  Kawashima Hidekazu, Nakano Atsushi, Zeniya Tutomu, Kakino Akemi, Miyake Yoshinori, Sawamura Tatsuya, Iida Hidehiro
- Organizer
  World Molecular Imaging Congress　2012
- Place of Presentation
  London
- Data Source
  KAKENHI-PROJECT-24601021
[Presentation] アテローム性血管病変のイメージングを目的としたヨウ素-123標識酸化LDLの合成と基礎評価2012
- Author(s)
  河嶋秀和、中野厚史、銭谷勉、垣野明美、三宅義徳、沢村達也、飯田秀博
- Organizer
  第52回日本核医学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24601021
[Presentation] LOX-1 遺伝子欠損SHRSPの作製とその形質の予備的解析
- Author(s)
  垣野明美、李　蕾、池末昌弘、中野厚史、藤田佳子、岡澤　慎、真下知士、沢村達也
- Organizer
  第50回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  和歌山市
- Year and Date
  2014-12-05 – 2014-12-06
- Data Source
  KAKENHI-PROJECT-24601021
[Presentation] Whole body imaging of 123I-oxLDL distribution in mouse with high resolution SPECT system
- Author(s)
  中野厚史、銭谷勉、河嶋秀和、飯田秀博、沢村達也
- Organizer
  日本分子イメージング学会　第10回学会総会・学術集会 / JSMI 2015
- Place of Presentation
  東京
- Year and Date
  2015-05-20 – 2015-05-21
- Data Source
  KAKENHI-PROJECT-24601021
[Presentation] ヨウ素-123 標識酸化LDL（[123I]oxLDL）の体内動態に関する検討
- Author(s)
  河嶋秀和、中野厚史、銭谷勉、圓見純一郎、垣野明美、三宅義徳、沢村達也、飯田秀博
- Organizer
  第12回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24601021
[Presentation] AT1 directly interacting with LOX-1 mediates signal transduction induced by oxidized LDL
- Author(s)
  A. Kakino, K. Yamamoto, A. Nakano, L. Li, Y. Fujita, H. Rakugi, T. Sawamura
- Organizer
  82nd European Atherosclerosis Society Congress (EAS 2014)
- Place of Presentation
  Madrid, SPAIN
- Year and Date
  2014-05-31 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-24601021
[Presentation] Overexpression Of Del-1, An Oxidized LDL Blocking Protein, Suppressed Atherogenesis In Mice Without Lowering Oxidized LDL Concentration, But with Reducing LOX-1 Ligand Containing ApoB Activity (LAB)
- Author(s)
  A.Kakino, A. Nakano, Y. Fujita, T. Sawamura
- Organizer
  2014 Annual Meeting & Clinical Lab Expo
- Place of Presentation
  Chicago, USA
- Year and Date
  2014-07-27 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-24601021

1. SAWAMURA Tatsuya (30243033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. YAMAGUCHI Saburo (00182436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKANO ATSUSHI 中野 厚史

NAKANO Atsushi 中野 厚史

中野 厚史 ナカノ アツシ

Research Projects

Research Products

Co-Researchers

単一心筋細胞のエネルギー効率計測法の確立と新規心不全薬探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of a new mechanism involved in the pathogenesis of atherosclerosis based on the oxLDL kinetic imagingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Whole body imaging of 123I-oxLDL distribution in mouse with high resolution SPECT systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

STUDY ON THE SIGNIFICANCE OF LOX-1 IN OXIDATIVE STRESS-RELATED BIOLOGICAL RESPONSES

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

大動脈モデル流れ場における乱流遷移構造の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

大動脈血流に生じる乱流遷移構造の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

周期的間欠流に発生する乱流の時空間的構造の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

周期的間欠流に発生する乱流構造の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

周期的間欠流に発生する乱流構造の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 123I-Labeled oxLDL Is Widely Distributed Throughout the Whole Body in Mice2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lectin-like oxidized low density lipoprotein receptor 1-deficient mice show resistance to instability-induced osteoarthritis2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Developmental Endothelial Locus-1 (Del-1) Inhibits Oxidized Low-Density Lipoprotein Activity by Direct Binding, and Its Overexpression Attenuates Atherogenesis in Mice2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor.2015

Author(s)

NAKANO ATSUSHI 中野厚史

NAKANO Atsushi 中野厚史

中野厚史ナカノアツシ

[Presentation] 高解像度SPECT を用いたマウス酸化LDL全身分布イメージング2015