KIYOSAWA TOMOHARU 清澤智晴

… Alternative Names

KIYOSAWA Tomoharu 清澤智晴

清澤智晴キヨサワトモハル

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Researcher Number	90221217
External Links
Affiliation (Current)	2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院形成外科, 教授
Affiliation (based on the past Project Information) *help	2017 – 2021: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院形成外科, 教授 2016: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 病院形成外科, 教授 2015: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, その他部局等, 教授 2014: 防衛医科大学校病院, 准教授 2011 – 2014: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 病院, 准教授 … More 2013: 防衛医科大学校, 病院, 准教授 2012: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 准教授 2011: 防衛医科大学校, 病院, 准教授 1998 – 2001: 筑波大学, 臨床医学系, 講師 1994: Jichi Medical School, 医学部, 病院助手 Less
Review Section/Research Field	Principal Investigator Plastic surgery Except Principal Investigator Basic Section 56070:Plastic and reconstructive surgery-related / Plastic surgery / 広領域 / Dermatology / Biomedical engineering/Biological material science
Keywords	Principal Investigator キメララット / 創傷治癒 / 2系統ヌードラット / 血管新生 / PVGrnu / rnuラット / WAGrnu / 外科的キメララット / 同種異系移植 / allograft … More / 共焦点レーザー蛍光顕微鏡 / WAGラット / PVGラット / キメラ動物 / 蛍光抗体法 / 同種同系移植 / ヌードラット … More Except Principal Investigator 再生医療 / 幹細胞 / 脂肪由来幹細胞 / 幹細胞移植 / ナノシート / cytoskeleton / adhesion molecules / signal transduction / complements / IgG subclass / bullous diseases / 蛍光タンパク / 蛍光色素 / 細胞治療 / 線維芽細胞成長因子 / 創傷治癒 / 塩基性線維芽細胞成長因子 / 薬剤輸送 / cell to cell, cell to stroma interaction / autoimmune / 細胞骨格 / cell to cell interaction / chemotaxis / 自己免役 / cell to cell cell to stroma interaction / cytoskelton / Signal transduction / 補体 / IgG Subclass / 接着分子 / 自己免疫 / 水疱症 / cell to stroma interaction / auto immune / 血管腫 / EPR効果 / 近赤外レーザー / 金ナノロッド / インドシアニングリーン / 再生医学 / 移植・再生医療 / ナノ材料 / 生物・生体工学 / 生体材料 Less

Enhanced cellular engraftment of adipose-derived mesenchymal stem cell therapy by Nanosheets.
- Principal Investigator
  
  AOKI SHIMPO
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Nippon Medical School
  National Defense Medical College
Transplantation of adipose-derived stem cell using the absorbable nanosheet.
- Principal Investigator
  
  AOKI SHIMPO
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  National Defense Medical College
Protein and stem cell-delivery systems using nanoparticles of narural polymer composites
- Principal Investigator
  
  ISHIHARA Masayuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  National Defense Medical College
Combination of indocyanine green and gold nano-particles for diagnosis and treatment of tumors and vascular abnormality
- Principal Investigator
  
  AZUMA Ryuichi
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  National Defense Medical College
系統ヌードラットキメラによる創傷治癒過程の血管新生に関する3次元的形態学的研究Principal Investigator
- Principal Investigator
  
  清澤智晴
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Plastic surgery
- Research Institution
  University of Tsukuba
創傷治癒研究に幅広く応用できる2系統ヌードラット由来キメラ動物実験モデルの作成Principal Investigator
- Principal Investigator
  
  清澤智晴
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Plastic surgery
- Research Institution
  University of Tsukuba
Research on the mechanism of bullous diseases---Immunological and biological studies---
- Principal Investigator
  
  YAOITA Hideo
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  JICHI MEDICAL SCHOOL

All 2021 2018 2017 2014 2013 2011

All Journal Article Presentation

[Journal Article] Angiogenic efficacy of <scp>ASC</scp> spheroids filtrated on porous nanosheets for the treatment of a diabetic skin ulcer2021
- Author(s)
  Suematsu Yoshitaka、Nagano Hisato、Kiyosawa Tomoharu、Takeoka Shinji、Fujie Toshinori
- Journal Title
  
  Journal of Biomedical Materials Research Part B: Applied Biomaterials
  
  Volume: 110 Issue: 6 Pages: 1245-1254
- DOI
  10.1002/jbm.b.34995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09501, KAKENHI-PROJECT-23K21854
[Journal Article] Enhanced cellular engraftment of adipose-derived mesenchymal stem cell spheroids by using nanosheets as scaffolds2021
- Author(s)
  Nagano Hisato、Suematsu Yoshitaka、Takuma Megumi、Aoki Shimpo、Satoh Ayano、Takayama Eiji、Kinoshita Manabu、Morimoto Yuji、Takeoka Shinji、Fujie Toshinori、Kiyosawa Tomoharu
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-021-93642-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09780, KAKENHI-PROJECT-18K09501, KAKENHI-PROJECT-21H03038
[Journal Article] In situ transplantation of adipose tissue-derived stem cells organized on porous polymer nanosheets for murine skin defects2018
- Author(s)
  Nishiwaki Keisuke、Aoki Shimpo、Kinoshita Manabu、Kiyosawa Tomoharu、Suematsu Yoshitaka、Takeoka Shinji、Fujie Toshinori
- Journal Title
  
  Journal of Biomedical Materials Research Part B: Applied Biomaterials
  
  Volume: 印刷中 Issue: 5 Pages: 3061-3168
- DOI
  10.1002/jbm.b.34228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K20116, KAKENHI-PLANNED-18H05469, KAKENHI-PROJECT-18H02907, KAKENHI-PROJECT-15K10961, KAKENHI-PROJECT-17K10682
[Journal Article] The efficacy of basic fibroblast growth factor-loaded poly(lactic-co-glycolic acid) nanosheet for mouse wound healing.2018
- Author(s)
  Shimpo Aoki MD, PhD Mao Fujii MSc Toshinori Fujie PhD Keisuke Nishiwaki MSc Hiromi Miyazaki PhD Daizoh Saitoh MD, PhD Shinji Takeoka PhD Tomoharu Kiyosawa MD, PhD Manabu Kinoshita MD, PhD
- Journal Title
  
  Wound Repair and Regeneration.
  
  Volume: 25(6) Pages: 100-1016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10961
[Journal Article] Effective wound healing in streptozotocin-induced diabetic rats by adipose-derived stromal cell transplantation in plasma-gel containing fragmin/protamine microparticles.2014
- Author(s)
  Sumi Y, Ishihara M, Kishimoto S, Takikawa M, Hattori H, Takikawa M, Azuma R, Nakamura S, Fujita M, Kiyosawa T.
- Journal Title
  
  Annals of Plastic Surgery
  
  Volume: 72 Issue: 1 Pages: 113-120
- DOI
  10.1097/sap.0000000000000014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25850226, KAKENHI-PROJECT-23300181
[Journal Article] Three-Dimensional Expansion Using Plasma-Medium Gel with Fragmin/Protamine Nanoparticles and FGF-2 to Stimulate Adipose-Derived Stromal Cells and Bone Marrow-Derived Mesenchymal Stem Cells2013
- Author(s)
  Satoko Kishimoto. Masayuki Ishihara, Yasutaka Mori, Megumi Takikawa, Yuki Sumi, Shingo Nakamura, Toshinori Sato, Tomoharu Kiyosawa
- Journal Title
  
  BioResearch Open Access
  
  Volume: 1(6) Issue: 6 Pages: 314-323
- DOI
  10.1089/biores.2012.0251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J40089, KAKENHI-PROJECT-23300181
[Journal Article] Fragmin/protamine microparticles to adsorb and protect HGF and to function as local HGF carriers in vivo2013
- Author(s)
  Kishimoto S, Ishihara M, Nakamura S, Fujita M, Takikawa M, Sumi Y, Kiyosawa T, Sato M, Maehara T.
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 9 Pages: 4763-4770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300181
[Journal Article] TransPlantation of Inbred AdiPose一Derived Stromal Cells in Rats with Plasma Gel Containing Fragmin/Protamine MicroParticles and FGF-22013
- Author(s)
  Sumi Y, Ishihara M, KishimotoS, TakikawaM, Doumoto T, AZUma R, Nakamura S, Hattori H, Fujita M,Kiyosawa T
- Journal Title
  
  J.Biomed.Mater.Res.PartB
  
  Volume: 101B Pages: 784-791
- Data Source
  KAKENHI-PROJECT-23300181
[Journal Article] Fragmin/protamine microparticles to adsorb and protect HGF and to function as local HGF carriers in vivo2013
- Author(s)
  Satoko Kishimoto. Masayuki Ishihara, Shingo Nakamua, Masanori Fujita, Megumi Takikawa, Yuki Sumi, Tomoharu Kiyosawa, Toshinori Sato, Yasuhiro Kanatani
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 9(1) Issue: 1 Pages: 4763-4770
- DOI
  10.1016/j.actbio.2012.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J40089, KAKENHI-PROJECT-22780274, KAKENHI-PROJECT-23300181
[Journal Article] Transplantation of inbred adipose aderived stromal cells in rats with plasm a gel containing fragmin/protamine microparticles and FGF-22013
- Author(s)
  Sumi Y, Ishihara M, Kishimoto S, Takikawa M, Doumoto T, Azuma R, Nakamura S, Hattori H, Fujita M, Kiyosawa T
- Journal Title
  
  Journal of Biomedical Materials Research. Part B, Applied Biomaterials
  
  Volume: (掲載確定) Issue: 5 Pages: 784-891
- DOI
  10.1002/jbm.b.32882
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J40089, KAKENHI-PROJECT-23300181
[Journal Article] Three-dimensional culture using human plasma-medium gel with fragmin/protamine microparticles for proliferation of various human cells2013
- Author(s)
  Kishimoto S, Ishihara M, Takikawa M, Takikawa M, Sumi Y, Nakamura S, Fujita M, Sato T, Kiyosawa T.
- Journal Title
  
  Cytotechnology
  
  Volume: 2013 Issue: 5 Pages: 1-12
- DOI
  10.1007/s10616-013-9628-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300181
[Journal Article] PRP&F/P MPs improved survival of dorsal paired pedicle skin flaps in rats2011
- Author(s)
  Takikawa M, Sumi Y, Ishihara M, Kishimoto S, Nakamura S, Yanagibayashi S, Hattori H, Azuma R, Yamamoto N, Kiyosawa T
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 170 (1) Pages: 189-190
- Data Source
  KAKENHI-PROJECT-23300181
[Journal Article] Increased survival of free fat grafts and vascularization in rats with local delivery of fragmin/protamine microparticles containing FGF-2 (F/P MP-F)2011
- Author(s)
  Nakamura S, Ishihara M, Takikawa M, Murakami K, Kishimoto S, Nakamura S, Yanagibayashi S, Fujita M, Kubo S, Yamamoto N, Kiyosawa T
- Journal Title
  
  Journal of Biomedical Materials Research (B)
  
  Volume: 96B Issue: 2 Pages: 234-241
- DOI
  10.1002/jbm.b.31757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300181
[Journal Article] Enhanced effect of platelet-rich plasma containing a new carrier on hair growth2011
- Author(s)
  Megumi Takikawa, Shin-ichiro Nakamura, Shingo Nakamura, Masayuki Ishirara, Satoko Kishimoto, Kaoru Sasaki, Satoshi Yanagibayashi, Ryuichi Azuma, Naoto Yamamoto, Tomoharu Kiyosawa
- Journal Title
  
  Dermatologic Surgery
  
  Volume: 37(12) Issue: 12 Pages: 1721-1729
- DOI
  10.1111/j.1524-4725.2011.02123.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J40089, KAKENHI-PROJECT-23300181
[Journal Article] Stimulatory effect of autologous adipose tissue-derived stromal cells in an atelocollagen matrix on wound healing in diabetic db/db mice2011
- Author(s)
  Nambu M et al
- Journal Title
  
  J Tissue Eng
  
  Volume: 2011 Pages: 1-7
- DOI
  10.4061/2011/158105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592655, KAKENHI-PROJECT-23300181
[Journal Article] Stimilation of vascularization and granulation tisuue formation by growth factors in human platelet-rich plasma (PRP) containing fragmin/protamine micro particles (F/P MPs)2011
- Author(s)
  Takikawa M, Nakamura S-I, Nakamura S, Nambu M, Ishihara M, Murakami K, Kishimoto S, Sasaki K, Yanagishita S, Azuma R, Yamamoto N, Kiyosawa T
- Journal Title
  
  J. Biomed. Mater. Res(B)
  
  Volume: 97B (2) Issue: 2 Pages: 373-380
- DOI
  10.1002/jbm.b.31824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300181
[Presentation] Basic fibroblast growth factor-loaded PLGA nanosheet promotes wound healing of refractory skin lesions(増殖因子担持ナノシートの難治性皮膚潰瘍に対する被覆治療効果)2017
- Author(s)
  Manabu Kinoshita,Nariyoshi Shinomiya,Aoki Shimpo,Tomoharu Kiyosawa,ShujiSeki
- Organizer
  Chemical and Biological Defense Science & Technology Conference
- Data Source
  KAKENHI-PROJECT-15K10961
[Presentation] 多血小板血漿含有フラグミン・プロタミン・マイクロパーティクルによる創傷治癒促進効果2011
- Author(s)
  瀧川恵美、鷲見友紀、石原雅之、岸本聡子、柳林聡、東隆一、山本直人、清澤智晴
- Organizer
  第20回日本形成外科学会基礎学術集会
- Place of Presentation
  東京
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-23300181

1. MORIMOTO Yuji (10449069)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. AOKI SHIMPO (70739797)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. 木下学 (70531391)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 藤枝俊宣 (70538735)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. ISHIHARA Masayuki (10508500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. ISHIHARA Miya (30505342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. MAEHARA Masaaki (70124956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. AZUMA Ryuichi (00531112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAOITA Hideo (00010249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMANE Yasuhiro (70220431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MURATA Satoru (70254919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SUZUKI Masayuki (40171251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KATAYAMA Hiroshi (50142401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 藤田真敬 (20525927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
15. 出光俊郎 (20237027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 北島康雄 (70111797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 狩野俊幸 (10204596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 宮崎裕美 (30531636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 齋藤大蔵 (90531632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. NAKAMURA Shingo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. TAKAYAMA Eiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 佐藤あやの

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KIYOSAWA TOMOHARU 清澤 智晴

KIYOSAWA Tomoharu 清澤 智晴

清澤 智晴 キヨサワ トモハル

Research Projects

Research Products

Co-Researchers

Enhanced cellular engraftment of adipose-derived mesenchymal stem cell therapy by Nanosheets.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Transplantation of adipose-derived stem cell using the absorbable nanosheet.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protein and stem cell-delivery systems using nanoparticles of narural polymer composites

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Combination of indocyanine green and gold nano-particles for diagnosis and treatment of tumors and vascular abnormality

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

系統ヌードラットキメラによる創傷治癒過程の血管新生に関する3次元的形態学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

創傷治癒研究に幅広く応用できる2系統ヌードラット由来キメラ動物実験モデルの作成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the mechanism of bullous diseases---Immunological and biological studies---

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Angiogenic efficacy of <scp>ASC</scp> spheroids filtrated on porous nanosheets for the treatment of a diabetic skin ulcer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhanced cellular engraftment of adipose-derived mesenchymal stem cell spheroids by using nanosheets as scaffolds2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In situ transplantation of adipose tissue-derived stem cells organized on porous polymer nanosheets for murine skin defects2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The efficacy of basic fibroblast growth factor-loaded poly(lactic-co-glycolic acid) nanosheet for mouse wound healing.2018

Author(s)

Journal Title

Data Source

[Journal Article] Effective wound healing in streptozotocin-induced diabetic rats by adipose-derived stromal cell transplantation in plasma-gel containing fragmin/protamine microparticles.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Three-Dimensional Expansion Using Plasma-Medium Gel with Fragmin/Protamine Nanoparticles and FGF-2 to Stimulate Adipose-Derived Stromal Cells and Bone Marrow-Derived Mesenchymal Stem Cells2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fragmin/protamine microparticles to adsorb and protect HGF and to function as local HGF carriers in vivo2013

Author(s)

Journal Title

KIYOSAWA TOMOHARU 清澤智晴

KIYOSAWA Tomoharu 清澤智晴

清澤智晴キヨサワトモハル

[Presentation] Basic fibroblast growth factor-loaded PLGA nanosheet promotes wound healing of refractory skin lesions(増殖因子担持ナノシートの難治性皮膚潰瘍に対する被覆治療効果)2017