Sugiyama Fumihiro 杉山文博

… Alternative Names

Researcher Number	90226481
Other IDs
External Links
Affiliation (Current)	2020: 筑波大学, 医学医療系, 教授
Affiliation (based on the past Project Information) *help	2015 – 2020: 筑波大学, 医学医療系, 教授 2011 – 2016: 筑波大学, 医学医療系, 准教授 2014: 筑波大学, 人間総合科学研究科, 准教授 2011 – 2012: 筑波大学, 人間総合科学研究科, 准教授 2007 – 2010: University of Tsukuba, 大学院・人間総合科学研究科, 准教授 … More
Review Section/Research Field	Principal Investigator Laboratory animal science / Laboratory animal science / Biological Sciences / Laboratory animal science / Kidney internal medicine / Nerve anatomy/Neuropathology / Medium-sized Section 42:Veterinary medical science, animal science, and related fields Except Principal Investigator Laboratory animal science / Laboratory animal science / Applied molecular and cellular biology … More
Keywords	Principal Investigator マウス / QTL / 血圧 / 高血圧 / トランスジェニックマウス / ES細胞 / 遺伝子改変マウス / 疾患モデル / アンギオテンシノーゲン / ENU … More Except Principal Investigator トランスジェニックマウス / ノックアウトマウス / パルボウイルス / 炎症性肺疾患 / p38 / 遺伝子改変マウス / マウス / アンギオテンシンII / つくば高血圧マウス / つくば低血圧マウス / レニン・アンギオテンシン系 / アンジオテンシノーゲン / transgenic mouse / NS / ラットウイルス / PCR / トランスジェニックラット / p38MAPK / 肺胞II型上皮細胞 / COPD / 間質性肺炎 / 応用動物 / バイオテクノロジー / 動物 / 遺伝子 / 動物モデル / in vivoイメージング / 蛍光タンパク質 / 慢性閉塞性肺疾患 / APJ受容体 / 炎症 / ゲノム編集 / Exoc1 / ラット / レニン / トランスジェニック・マウス / renin / angiotensinogen / transgenic mice / アポトーシス / renin-angiotensin system / PNET / E1A / E1B / Parvovirus / Transgenic mice / 動脈硬化 / 受容体 / 高血圧 / 妊娠 / アンジオテンシンII / 精子形成 / CRP / イメージング / 遺伝子診断 / ヒト高血圧症モデル / ヒトレニン / ヒトアンギオテンシノーゲン / MKK6 / ペプチド性阻害薬 / 神経科学 / 蛍光イメージング / Tgマウス / 神経活動 / 薬物動態 / 発光タンパク質 / 肺由来幹・前駆細胞 / CD69 / 妊娠恒常性 / 周産期心筋症 / 特発性肺線維症 / 肺胞上皮前駆細胞 / 細胞治療 / 線維化肺 / サイトカイン / ケモカイン / 肺疾患 / 幹・前駆細胞 / リサーチバイオリソース / 近赤外蛍光タンパク質 / 近赤外 / 工学的窓 / 光学的窓 / 応用科学 / 着床障害 / 自然突然変異 / 大規模ゲノム欠損 / 着床傷害 / 染色体 / 連鎖地図 / 反復配列 / マーカー遺伝子 / 多型性 / PCR法 / アンギオテンシノーゲン / アンギオテンシン受容体 / ノックアウト・マウス / 低血圧マウス / 妊娠高血圧マウス / アンギオテンシンノーゲン遺伝子 / ジーンターゲテイング法 / アンギオテンシンII受容体欠損マウス / アンギオテンシノーゲン遺伝子 / アンギオテンシンI / angiotensin II / angiotensin-receptor / knock out mice / Hypotensin / Hypertension induced by pregnancy / アンギオテンシンII(IV) / アンギオテンシンII受容体 / 海馬 / 小脳 / アンギオテンシンIV / 遺伝子欠損マウスス / ホモ欠損マウス / ヘテロ欠損マウス / アルドステロン / 心肥大 / knock out mouse / cerebellum / angiotensin II receptors / apoptosis / Hippocampus / EIA / EIB / アデリウィルス / ヒルシュスプルング病 / 髄芽腫 / アデノウィルス / PNTT / 神経芽腫 / Transgenic mouse / Adenovirus / Hirschsprung Disease / Medulloblastoma / テトラサイクリン発現誘導システム / 細胞傷害性 / 病原性 / Nonstractural protein / Tet-inducible system / Cytotoxicity / 食塩 / 腎臓 / 大動脈瘤 / 動脈硬化症 / コレステロール / 脂肪 / 臓器傷害 / Tsukuba hypertensive mouse / malignant hypertension / Vascular remodeling / 酵母遺伝学 / angiotensin / pregnancy / blood pressure / hypertension / knock-out mice / hypertrophy / グロビン / インシュレーター / YAC(酵母人工染色体) / globin / insulator / YAC / 胸腺リンパ腫細胞 / サブトラクション / CNTFRα / 宿主遺伝子 / Tリンパ腫細胞 / 遺伝子発現 / parvovirus / rat / thymic lymphoma cell / subtraction / CNTFR_α / Foxo1 / CBP / アセチル化 / フォークヘッド転写因子 / 転写共役因子 / ユビキチン化 / インスリン / 多重修飾 / FKHR / Foxol / CREB-binding protein (CBP) / acetylation / forkhead transcription factor / transcriptional cofactor / ubiquitination / insulin / multiple modification / P4プロモーター / エピジェネシス / ヒストンアセチル化 / 病態モデルマウス / 病態モデル / P4 promoter / Epigenetics / Histone acetylation / 遺伝子改変ウサギ / C反応性蛋白 / 高脂血症 / マクロファージ / プラーク / 実験モデル / C-反応蛋白 / 遺伝子改変 / 脂質代謝 / 遺伝子導入 / Transgenic rabbits / Atherosclerosis / Hypercholesterolemia / Macrophages / Plaque / Animal model / Inflammation / 栄養 / 血管 / PRMT1 / 内皮細胞特異的ノックアウトマウス / 透明化 / 二光子顕微鏡 / 代謝 / 血管内皮細胞 / 栄養補給路 / アルギニンメチル化酵素 / 内皮細胞 / 血管収縮 / アドレナリン受容体 / シグナル伝達 / 受容体間相互作用 / 分子間相互作用 / 受精卵ゲノム編集 / マウスリソース開発 / ヒト化マウス / 卵子形成 / エキソシスト複合体 / 胚発生 / 精巣 / 卵巣 / 初期胚 / 配偶子 / EXOC1 / 初期胚発生 / 配偶子形成 / 腫瘍血管新生 / 血管新生 Less

Biological functions of alternative splicing on mouse gastrulationPrincipal InvestigatorOngoing
- Principal Investigator
  
  杉山文博
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  University of Tsukuba
Elucidation of the molecular mechanism to maintain hierarchical structure of vascular system and and tumour angiogenesisOngoing
- Principal Investigator
  
  依馬正次
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Shiga University of Medical Science
Functional analysis of Exoc1 gene involved in embryonic development and gametogenesis
- Principal Investigator
  
  Yagami Ken-ichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Development of mouse-non-human primate chimera analysis innovating evaluation methods of human pluripotent stem cellsPrincipal Investigator
- Principal Investigator
  
  Sugiyama Fumihiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Development of bicistronic cre driver mice using CRISPR/Cas9Principal Investigator
- Principal Investigator
  
  SUGIYAMA Fumihiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Development of new in vivo imaging technologies by using biological optical window
- Principal Investigator
  
  Takahashi Satoru
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Functional analysis of Exoc1 gene related to embryo implamtation
- Principal Investigator
  
  YAGAMI Ken-ichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Cooperative action of APJ and alpha1A-adrenrgic receptor in vascular smooth muscle cells induces intensive vasoconstriction
- Principal Investigator
  
  ISHIDA Junji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Genetic humanized Mouse production by CRISPITT
- Principal Investigator
  
  MIZUNO Seiya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Integrative animal science
  Laboratory animal science
- Research Institution
  University of Tsukuba
Functional roles of arginine methylation on vascular networks for nutritional supply
- Principal Investigator
  
  FUKAMIZU Akiyoshi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  University of Tsukuba
The study of strategic therapy for inflammatory pulmonary diseases
- Principal Investigator
  
  KASUYA Yoshitoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Chiba University
Study on the pathogenesis of peripertum cardiomyopathy using genetically modified mouse model
- Principal Investigator
  
  ISHIDA Junji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Development of rat ES cells carrying rat Nanog reporter genePrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Fmihiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Development of basic technologies for new in vivo imaging to promote life science research
- Principal Investigator
  
  TAKAHASHI Satoru
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
The study of molecular mechanism and new therapeutic strategy for the pathogenesis of inflammatory pulmonary di sease
- Principal Investigator
  
  KASUYA Yoshitoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Chiba University
マウス第18番染色体における脳梁欠損症原因遺伝子の発見Principal Investigator
- Principal Investigator
  
  杉山文博
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  University of Tsukuba
Development of consomic mouse model for metabolic syndromePrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Fumihiro
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
The study of molecular mechanism for inflammatory pulmonary disease
- Principal Investigator
  
  KASUYA Yoshitoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Chiba University
Nphs2遺伝子変異マウスの血圧解析Principal Investigator
- Principal Investigator
  
  杉山文博
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba
Quantitative trait locus analysis of spontaneously hypertensive micePrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Fumihiro
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Elucidation of C-reactive proteins in atherosclerosis
- Principal Investigator
  
  FAN Jianglin
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Yamanashi
  University of Tsukuba
Development of Disease Model Mice for Parvovirus-Related Disorder and Pathogenic Mechanism
- Principal Investigator
  
  YAGAMI Ken-ichi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Functional Network of Transcriptional Control Factors Regulated by Multiple Modifications
- Principal Investigator
  
  FUKAMIZU Akiyoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  University of Tsukuba
化学誘導血圧変異マウスの開発と高血圧遺伝子座の解析Principal Investigator
- Principal Investigator
  
  杉山文博
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Inhibition of enhancer-promoter interaction involved in the developmental-stage specific gene regulation
- Principal Investigator
  
  TANIMOTO Keiji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  University of Tsukuba
Modification of host genes in the infected cells with parvovirus
- Principal Investigator
  
  YAGAMI Kenichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
低血圧マウスを基盤とした化学誘導血圧変異マウスの開発Principal Investigator
- Principal Investigator
  
  杉山文博
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Blood pressure QTL in micePrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Fumihiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Molecular mechanism of hypertension on pregnant transgenic mice.
- Principal Investigator
  
  MURAKAMI Kazuo
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  FOUNDATION FOR ADVANCEMENT OF INTERNATIONAL SCIENCE
  University of Tsukuba
A new mouse model for pregnancy-induced hypertension.
- Principal Investigator
  
  FUKAMIZU Akiyoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  University of Tsukuba
Development of C57BL/6J-AgtKO micePrincipal Investigator
- Principal Investigator
  
  FUKAMIZU Akiyoshi, 杉山文博
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Creation and analysis of transgenic and knockout animals in hypertension and its related diseases.
- Principal Investigator
  
  MURAKAMI Kazuo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  UNIVERSITY OF TSUKUBA
Etiological Study of Neuroectodermal Tumor and Hirschsprung Disease using transgenic Mice
- Principal Investigator
  
  KANEKO Michio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  小児外科
- Research Institution
  University of Tsukuba
Generation and analysis of transgenic mice carrying parvoviral NS gene
- Principal Investigator
  
  YAGAMI Ken-ichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
ヒト高血圧症モデル動物としてのトランスジェニックマウス・ラットの実用化の研究
- Principal Investigator
  
  NOMURA Tatuji
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Development of Pluripotential Embryonic Stem Cells from Rat BlastocystPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Fumihiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Development of Atherosclerosis on Tsukuba Hypertensive MicePrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Fumihiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
外因性誘導による高血圧トランスジェニックマウス系統の確立Principal Investigator
- Principal Investigator
  
  杉山文博
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Transgenic mice and knock out mice in renin-angiotensin system.
- Principal Investigator
  
  MURAKAMI Kazuo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  UNIVERSITY OF TSUKUBA
神経芽腫を形成するトランスジェニックマウス系統の確立Principal Investigator
- Principal Investigator
  
  杉山文博
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
ラットウイルス(RV)感染の遺伝子診断に関する研究
- Principal Investigator
  
  YAGAMI Ken-ichi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
ラットウイルス(RV)感染の遺伝子診断に関する研究
- Principal Investigator
  
  八神健一, 国枝哲夫
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Institute for Animal Reproduction
  University of Tsukuba

[Journal Article] Generation of bicistronic reporter knockin mice for visualizing germ layers2019
- Author(s)
  Suzuki H, Dinh TTH, Daitoku Y, Tanimoto Y, Kato K, Azami T, Ema M, Murata K, Mizuno S, Sugiyama F.
- Journal Title
  
  Experimental Animals
  
  Volume: 68 Issue: 4 Pages: 499-509
- DOI
  10.1538/expanim.19-0031
- NAID
  130007662942
- ISSN
  1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03568
[Journal Article] A Novel iRFP-Incorporated in vivo Murine Atherosclerosis Imaging System2018
- Author(s)
  Kulathunga K, Hamada M, Hiraishi Y, Otake M, Tran MTN, Cheng O, Tanaka J, Sakasai T, Sakaguchi S, Sugiyama Y, Fleischmann BK, Takahashi S, Miwa Y
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Pages: 14515-14515
- DOI
  10.1038/s41598-018-32456-5
- NAID
  120006542254
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05935, KAKENHI-PROJECT-26221004, KAKENHI-PUBLICLY-16H01630
[Journal Article] Angiodysplasia in embryo lacking protein arginine methyltransferase 1 in vascular endothelial cells2017
- Author(s)
  Ishimaru, T., Ishida, J., Kim, JD., Mizukami, H., Hara, K., Hashimoto, M., Yagami, KI., Sugiyama, F., and Fukamizu, A.
- Journal Title
  
  J. Biochem.
  
  Volume: 161 Pages: 255-258
- DOI
  10.1093/jb/mvw095
- NAID
  40021162038
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25252062, KAKENHI-PROJECT-26430086, KAKENHI-PROJECT-15K14707, KAKENHI-PROJECT-17K07131
[Journal Article] Simple generation of hairless mice for in vivo imaging.2017
- Author(s)
  Hoshino Y, Mizuno S, Kato K, Mizuno-Iijima S, Tanimoto Y, Ishida M, Kajiwara N, Sakasai T, Miwa Y, Takahashi S, Yagami KI, Sugiyama F
- Journal Title
  
  Experimental Animals
  
  Volume: 66(4) Issue: 4 Pages: 437-445
- DOI
  10.1538/expanim.17-0049
- NAID
  130006187194
- ISSN
  1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05935, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-15H04281, KAKENHI-PROJECT-16K14589, KAKENHI-PROJECT-16H06276, KAKENHI-PUBLICLY-16H01630
[Journal Article] SHISA6 confers resistance to differentiation-promoting Wnt/6-catenin aignaling in mouse spermatogenic stem cells.2017
- Author(s)
  Tokue M, Jkami K, Mizuno S, Takagi C, Miyagi A, Takada R, Noda C, Kitadate Y, Hara K, Mizuguchi H, Sato T, Taketo MM, Sugiyama F, Ogawa T, Kobayashi S, Ueno N, Takahashi S, Takada S, Yoshida S.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 8 Pages: 561-575
- DOI
  10.1016/j.stemcr.2017.01.006
- NAID
  120006224053
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01523, KAKENHI-PLANNED-15H05865, KAKENHI-PLANNED-25114004, KAKENHI-PLANNED-25114007, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-15H04380, KAKENHI-PROJECT-26713012, KAKENHI-PROJECT-26450453, KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H00596, KAKENHI-ORGANIZER-15H05856, KAKENHI-PLANNED-24111002, KAKENHI-PUBLICLY-17H05782, KAKENHI-PLANNED-25114002
[Journal Article] Embryonic Intra-Aortic Clusters Undergo Myeloid Differentiation Mediated by Mesonephros-Derived CSF1 in Mouse.2016
- Author(s)
  Sasaki T, Tanaka Y, Kulkeaw K, Yumine-Takai A, Tan KS, Nishinakamura R, Ishida J, Fukamizu A, Sugiyama D.
- Journal Title
  
  Stem Cell Review
  
  Volume: 12 Pages: 530-542
- DOI
  10.1007/s12015-016-9668-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J07747, KAKENHI-PROJECT-26430086
[Journal Article] Generation of CRISPR/Cas9-mediated bicistronic knock-in <i>ins1-cre</i> driver mice2016
- Author(s)
  Yoshikazu Hasegawa, Yoshikazu Hoshino, Abdelaziz E. Ibrahim, Kanako Kato, Yoko Daitoku1, Yoko Tanimoto, Yoshihisa Ikeda, Hisashi Oishi, Satoru Takahashi, Atsushi Yoshiki, Ken-ichi Yagami, Hiroyoshi Iseki, Seiya Mizuno, Fumihiro Sugiyama
- Journal Title
  
  Experimental Animals
  
  Volume: 65 Issue: 3 Pages: 319-27
- DOI
  10.1538/expanim.16-0016
- NAID
  130006882371
- ISSN
  1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14359, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26290028, KAKENHI-PROJECT-26460356, KAKENHI-PROJECT-15K20888, KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-16K14588
[Journal Article] Germline recombination in a novel Cre transgenic line, Prl3b1-Cre mouse.2016
- Author(s)
  Al-Soudy AS, Hiromori Y, Mizuno S, Hasegawa Y, Shawki HH, Katoh MC, Basha WA, Ibrahim AE, El-Shemy HA, Iseki Hi, Yoshiki A, Nagase H, Nakanishi T, Takahashi S, Oishi H, Sugiyama F.
- Journal Title
  
  Genesis
  
  Volume: 54(7) Pages: 389-397
- DOI
  10.1002/dvg.22944
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-25281026, KAKENHI-PROJECT-25293031, KAKENHI-PROJECT-26290028, KAKENHI-PROJECT-15K14989, KAKENHI-PROJECT-15K20888, KAKENHI-PROJECT-15K00560, KAKENHI-PROJECT-16K15150
[Journal Article] Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation.2015
- Author(s)
  Mizuno S, Takami K, Daitoku Y, Tanimoto Y, Dinh TT, Mizuno-Iijima S, Hasegawa Y, Takahashi S, Sugiyama F, Yagami K.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Pages: 13632-13632
- NAID
  120005661898
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26221004
[Journal Article] Erythropoiesis and Blood Pressure Are Regulated via AT1 Receptor by Distinctive Pathways.2015
- Author(s)
  Kato H, Ishida J, Matsusaka T, Ishimaru T, Tanimoto K, Sugiyama F, Yagami K, Nangaku M, Fukamizu A
- Journal Title
  
  PLoS One.
  
  Volume: 10
- DOI
  10.1371/journal.pone.0129484
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-26430086, KAKENHI-PROJECT-23249047, KAKENHI-PROJECT-25252062
[Journal Article] Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation.2015
- Author(s)
  Seiya Mizuno, Kohei Takami, Yoko Daitoku, Yoko Tanimoto, Tra Thi Huong Dinh, Saori Mizuno-Iijima, Yoshikazu Hasegawa, Satoru Takahashi, Fumihiro Sugiyama, Ken-ichi Yagami
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Pages: 13632-13632
- DOI
  10.1038/srep13632
- NAID
  120005661898
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26640050, KAKENHI-PROJECT-26290028
[Journal Article] Simple generation of albino C57BL/6J mice with G291T mutation in the tyrosinase gene by the CRISPR/Cas9 system.2014
- Author(s)
  Mizuno S, Dinh TT, Kato K, Mizuno-Iijima S, Tanimoto Y, Daitoku Y, Hoshino Y, Ikawa M, Takahashi S, Sugiyama F, Yagami K.
- Journal Title
  
  Mamm Genome.
  
  Volume: 25(7-8) Pages: 327-34
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26221004
[Journal Article] A mouse renin distal enhancer is essential for blood pressure homeostasis in BAC-rescued renin-null mutant mice.2014
- Author(s)
  Tanimoto K, Kanafusa S, Ushiki A, Matsuzaki H, Ishida J, Sugiyama F, Fukamizu A
- Journal Title
  
  J. Recept. Signal Transduct. Res.
  
  Volume: 34 Pages: 401-409
- DOI
  10.3109/10799893.2014.908917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25252062, KAKENHI-PROJECT-25660248, KAKENHI-PROJECT-26430086
[Journal Article] Generation and Characterization of Ins1-cre-driver C57BL/6N for Exclusive Pancreatic Beta Cell-specific Cre-loxP Recombination2014
- Author(s)
  Hasegawa Y, Daitoku Y, Mizuno S, Tanimoto Y, Mizuno-Iijima S, Matsuo M, Kajiwara N, Ema M, Oishi H, Miwa Y, Mekada K, Yoshiki A, Takahashi S, Sugiyama F, Yagami K
- Journal Title
  
  Exp Animal
  
  Volume: 63 Pages: 183-191
- NAID
  130003391621
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/24770644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220009
[Journal Article] Simple generation of albino C57BL/6J mice with G291T mutation in the tyrosinase gene by the CRISPR/Cas9 system2014
- Author(s)
  Mizuno S, Dinh TT, Kato K, Mizuno-Iijima S, Tanimoto Y, Daitoku Y, Hoshino Y, Ikawa M, Takahashi S, Sugiyama F, Yagami KI.
- Journal Title
  
  Mammalian Genome
  
  Volume: 25 Pages: 327-334
- DOI
  10.1007/s00335-014-9524-0
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-26870077
[Journal Article] In vivo image analysis using iRFP transgenic mice.2014
- Author(s)
  Tran MT, Tanaka J, Hamada M, Sugiyama Y, Sakaguchi S, Nakamura M, Takahashi S, Miwa Y.
- Journal Title
  
  Exp Anim.
  
  Volume: 63(3) Pages: 311-9
- NAID
  130004677824
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26221004
[Journal Article] p38 Mitogen-activated protein kinase accelerates emphysema in mouse model of chronic obstructive pulmonary disease.2014
- Author(s)
  Amano H, Murata K, Matsunaga H, Tanaka K, Yoshioka K, Kobayashi T, Ishida J, Fukamizu A, Sugiyama F, Sudo T, Kimura S, Tatsumi K, Kasuya Y.
- Journal Title
  
  J. Recept. Signal Transduct. Res.
  
  Volume: in press Pages: 299-306
- DOI
  10.3109/10799893.2014.896380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390137, KAKENHI-PROJECT-25252062, KAKENHI-PROJECT-25670256, KAKENHI-PROJECT-26430086
[Journal Article] Truncated Cables1 causes agenesis of the corpus callosum in mice.2014
- Author(s)
  Mizuno S, Dinh T, Mizobuchi A, Iseki H, Mizuno-Iijima S, Kim J-D, Ishida J, Matsuda Y, Kunita S, Fukamizu A, Yagami K, Sugiyama F
- Journal Title
  
  Lab Invest.
  
  Volume: 94 Pages: 321-330
- DOI
  10.1038/labinvest.2013.146
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22370081, KAKENHI-PLANNED-23113004, KAKENHI-PROJECT-23300152, KAKENHI-PROJECT-25252062, KAKENHI-PROJECT-26430086
[Journal Article] Novel ROSA26 Cre-reporter knock-in C57BL/6N mice exhibiting green emission before and red emission after Cre-mediated recombination2013
- Author(s)
  Hasegawa Y, Daitoku Y, Sekiguchi K, Tanimoto Y, Iijima S, Mizuno S, Kajiwara N, Ema M, Miwa Y, Mekada K, Yoshiki A, Takahashi S, Sugiyama F, Yagami K-I
- Journal Title
  
  Exp Animal
  
  Volume: 62 Pages: 295-304
- NAID
  130003382716
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/?term=Hasegawa+Y%2C+Daitoku+Y%2C+Sekiguchi+K
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220009
[Journal Article] Novel ROSA26 Cre-reporter knock-in C57BL/6N mice exhibiting green emission before and red emission after Cre-mediated recombination2013
- Author(s)
  Hasegawa Y, Daitoku Y, Sekiguchi K, Tanimoto Y, Iijima S, Mizuno S, Ema M, Miwa Y, Mekada K, Yoshiki A, Takahashi S, Sugiyama F, Yagami K
- Journal Title
  
  Exp Anim
  
  Volume: 62(in press)
- NAID
  130003382716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650229
[Journal Article] Novel ROSA26 Cre-reporter knock-in C57BL/6N mice exhibiting green emission before and red emission after Cre-mediated recombination.2013
- Author(s)
  Hasegawa Y, Daitoku Y, Sekiguchi K, Tanimoto Y, Iijima S, Mizuno S, Kajiwara N, Ema M, Miwa Y, Mekada K, Yoshiki A, Takahashi S, Sugiyama F, Yagami K-i.
- Journal Title
  
  Experimental Animals
  
  Volume: 62 Pages: 295-304
- NAID
  130003382716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220009
[Journal Article] Effect of Lactation on Postpartum Cardiac Function of Pregnancy-Associated Hypertensive Mice2013
- Author(s)
  Murata, K., Saito, C., Ishida, J., Hamada, J., Sugiyama, F., Yagami, KI., and Fukamizu, A
- Journal Title
  
  Endocrinology
  
  Volume: 154 Pages: 597-602
- DOI
  10.1210/en.2012-1789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300152
[Journal Article] hort-term Suppression of Renin-Angiotensin System in Mice Associated with Hypertension during Pregnancy2012
- Author(s)
  Ishimaru, T., Ishida, J., Nakamura, S., Hashimoto, M., Matsukura, T., Nakamura, A., Kunita, S., Sugiyama, F., Yagami, K., and Fukamizu, A
- Journal Title
  
  Mol. Med. Reports
  
  Volume: 6 Pages: 28-32
- DOI
  10.3892/mmr.2012.886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300152
[Journal Article] Retrotransposon-mediated Fgf5^<go-Utr> mutant mice with long pelage hair.2011
- Author(s)
  Mizuno S, Iijima S, Okano T, Kajiwara N, Kunita S, Sugiyama F, Yagami K
- Journal Title
  
  Exp Anim 60
  
  Pages: 161-167
- NAID
  10029550360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300143
[Journal Article] Genetic analysis of blood pressure in 8 mouse intercross populations.2009
- Author(s)
  Feng M, Deerhake ME, Keating R, Thaisz J, Xu L, Tsaih SW, Smith R, Ishige T, Sugiyama F, Churchill GA, DiPetrillo K.
- Journal Title
  
  Hypertension 54
  
  Pages: 802-809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300143
[Journal Article] Genetic analysis of blood pressure in 8 mouse intercross populations.2009
- Author(s)
  Feng M, Deerhake ME, Keating R, Thaisz J, Xu L, Tsaih SW, Smith R, Ishige T, Sugiyama F, Churchill GA, DiPetrillo K
- Journal Title
  
  Hypertension 54
  
  Pages: 802-809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300143
[Journal Article] Genetic analysis of blood pressure in 8 mouse intercross populations2009
- Author(s)
  Feng M, Deerhake ME, Keating R, Thaisz J, Xu L, Tsaih SW, Smith R, Ishige T, Sugiyama F, Churchill GA, DiPetrillo K.
- Journal Title
  
  Hypertension 54
  
  Pages: 802-809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300143
[Journal Article] Angiotensin type 1 receptor blockade prevents cardiac remodeling in mice with pregnancy-associated hypertension.2008
- Author(s)
  Sakairi A, Ishida J, Honjo K, Inaba S, Nakamura S, Sugiyama F, Yagami K, Fukamizu A.
- Journal Title
  
  Hypertens Res 31
  
  Pages: 216-275
- NAID
  10024828642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300143
[Journal Article] Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells.2008
- Author(s)
  Kato H, Ishida J, Nagano K, Honjo K, Sugaya T, Takeda N, Sugiyama F, Yagami K, Fujita T, Nangaku M, Fukamizu A
- Journal Title
  
  Lab Invest. 88
  
  Pages: 731-739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300143
[Journal Article] Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells.2008
- Author(s)
  Kato H, Ishida J, Nagano K, Honjo K, Sugaya T, Takeda N, Sugiyama F, Yagami K, Fujita T, Nangaku M, Fukamizu A.
- Journal Title
  
  Lab Invest. 88
  
  Pages: 731-739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300143
[Journal Article] Quantitative trait loci associated with blood pressure of metabolic syndrome in the progeny of NZO/HILtJxC3H/HeJ intercrosses.2007
- Author(s)
  Nishihara E, Tsaih SW, Tsukahara C, Langley S, Sheehan S, DiPetrillo K, Kunita S, Yagami K, Churchill GA, Paigen B, Sugiyama F
- Journal Title
  
  Mamm Genome. 18
  
  Pages: 573-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300143
[Journal Article] Quantitative trait loci associated with blood pressure of metabolic syndrome in the progeny of NZO/HILtJxC3H/HeJ intercrosses2007
- Author(s)
  Nishihara E, Tsaih SW, Tsukahara C, Langley S, Sheehan S, DiPetrillo K, Kunita S, Yagami K, Churchill GA, Paigen B, Sugiyama F.
- Journal Title
  
  Mamm Genome. 18
  
  Pages: 573-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300143
[Journal Article] Development of ELISA using recombinant antigens for specific detection of mouse parvovirus infection.2006
- Author(s)
  Kunita S, Chaya M, Hagiwara K, Ishida T, Takakura A, Sugimoto T, Iseki H, Fuke K, Sugiyama F, Yagami K.
- Journal Title
  
  Experimental Animals 55・2
  
  Pages: 117-124
- NAID
  10018114688
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300139
[Journal Article] Development of ELISA using recombinant antigens for specific detection of mouse parvovirus infection.2006
- Author(s)
  Kunita S, Chaya M, Hagiwara K, Ishida T, Takakura A, Sugimoto T, Iseki H, Fuke K, Sugiyama F, Yagami K.
- Journal Title
  
  Experimental Animals 55(2)
  
  Pages: 117-124
- NAID
  10018114688
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300139
[Journal Article] Parvovirus nonstructural proteins induce an epigenetic modification through histone acetylation in host genes and revert tumor malignancy to benignancy.2005
- Author(s)
  Iseki H, Shimizukawa R, Sugiyama F, Kunita S, Iwama A, Onodera M, Nakauchi H, Yagami K.
- Journal Title
  
  Journal of Virology 79・14
  
  Pages: 8886-8893
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300139
[Journal Article] Parvovirus NS induces an epigenetic modification through histone acetylation in host genes and reverts tumor malignancy to benignancy2005
- Author(s)
  Hiroyoshi Iseki, Fumihiro Sugiyama, Satoshi Kunita, Ken-ichi Yagami et al.
- Journal Title
  
  Journal of Virology In press
- Data Source
  KAKENHI-PROJECT-15300139
[Journal Article] Parvovirus nonstructural proteins induce an epigenetic modification through histone acetylation in host genes and revert tumor malignancy to benignancy.2005
- Author(s)
  Iseki H, Shimizukawa R, Sugiyama F, Kunita S, Iwama A, Onodera M, Nakauchi H, Yagami K.
- Journal Title
  
  Journal of Virology 79(14)
  
  Pages: 8886-8893
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300139
[Journal Article] Reglatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type in blood pressure in vivo.2004
- Author(s)
  Ishida, J., Hashimoto, T., Hashimoto, Y., Nishiwaki, S., Iguchi, T., Harada, S., Sugaya, T., Matsuzaki, H., Yamamoto, R., Shiota, N., Okunishi, H., Kihara, M., Umemura, S., Sugiyama, F., Yagami, K., Kasuya, Y., Mochizuki, N., Fukamizu, A.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 26274-26279
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14206040
[Presentation] 原腸胚の胚葉形成を可視化するレポーターマウスの作製2019
- Author(s)
  鈴木　颯、Dinh TTH、大徳陽子、加藤花名子、飯島沙織、水野聖哉、杉山文博
- Organizer
  第66回日本実験動物学会
- Data Source
  KAKENHI-PROJECT-17H03568
[Presentation] マウス精子形成におけるExocyst複合体の機能解析2019
- Author(s)
  大澤優生、Elzeftawy Abdelaziz、八神健一、水野聖哉、杉山文博
- Organizer
  第112回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-17H03566
[Presentation] マウス精子形成におけるExocyst複合体の機能解析2019
- Author(s)
  大澤優生、Elzeftawy Abdelaziz、八神健一、水野聖哉、杉山文博
- Organizer
  第66回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-17H03566
[Presentation] Exocyst複合体のマウス卵母細胞における機能解析2019
- Author(s)
  久場ゆめの,　Shawki H.Hossam,　八神健一,　水野聖哉,　杉山文博
- Organizer
  第112回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-17H03566
[Presentation] マウス精子形成におけるfirst wave解析方法の確立2018
- Author(s)
  大澤優生、Elzeftawy Abdelaziz、大徳陽子、長谷川賀一、八神健一、水野聖哉、杉山文博
- Organizer
  第64回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-17H03566
[Presentation] 胚葉特異的ノックインレポーターマウスの作製2018
- Author(s)
  鈴木颯, Dinh Thi Houg Tra 大徳陽子, 加藤花名子, 飯島沙織, 水野聖哉, 杉山文博
- Organizer
  第65回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-17H03568
[Presentation] A novel creation of reporter mouse model for assessing gastrulation and three germ layer formation2018
- Author(s)
  Hayate Suzuki, Tra Dinh Thi Houg, Seiya Mizuno and Fumihiro Sugiyama
- Organizer
  TGSW2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03568
[Presentation] マウス精子形成におけるfirst wave解析方法の確立2018
- Author(s)
  大澤優生、Elzeftawy Abdelaziz、大徳陽子、長谷川賀一、八神健一、水野聖哉、杉山文博
- Organizer
  第65回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-17H03566
[Presentation] 原腸胚における遺伝子機能解析に有用な胚葉特異的レポーターマウスの作製2018
- Author(s)
  鈴木颯, Tra Dinh Thi Houg, 浅見拓哉, 大徳陽子, 加藤花名子, 飯島沙織, 水野聖哉, 依馬正次, 杉山文博
- Organizer
  日本ゲノム編集学会第3回大会
- Data Source
  KAKENHI-PROJECT-17H03568
[Presentation] CRISPR/Casを用いたマウスゲノム編集の実際2016
- Author(s)
  水野聖哉、高橋智、杉山文博、八神健一
- Organizer
  第121回日本解剖学会総会全国学術集会
- Place of Presentation
  ビッグパレットふくしま
- Year and Date
  2016-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-26870077
[Presentation] CRISPR/Casを用いたマウスゲノム編集の実際2016
- Author(s)
  水野聖哉、高橋智、杉山文博、八神健一
- Organizer
  第121回日本解剖学会総会全国学術集会
- Place of Presentation
  ビッグパレット福島（郡山市）
- Year and Date
  2016-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-26290028
[Presentation] CRISPR/Cas9を用いた膵β細胞特異的にCre酵素を発現するバイシストロニックCreドライバーマウスの開発2016
- Author(s)
  長谷川賀一、星野貴一、アブデラジーイブラヒム、加藤花名子、大徳陽子、谷本陽子、池田祥久、大石久史、高橋智、八神健一、伊関大敬、水野聖哉、杉山文博
- Organizer
  第６３回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎シンフォニーホール（神奈川県川崎市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K14359
[Presentation] CRISPR/Cas9システムを用いた多様な遺伝子改変マウス作製の実際2016
- Author(s)
  水野聖哉、高橋智、杉山文博
- Organizer
  生化学会大会
- Place of Presentation
  宮城県仙台市.仙台国際センター
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-26870077
[Presentation] Applied Genome Editing with CRISPR/Cas9 Plasmid in Mice2015
- Author(s)
  Seiya Mizuno, Kanako Kato, Saori Iijima, Yuko Hamada, Tra Dinh Thi Huong, Yoshikazu Hoshino, Yoko Tanimoto, Satoru Takahashi, Fumihiro Sugiyama, Ken-ichi Yagami
- Organizer
  トランスポゾン転移とゲノム編集技術に関する国際会議2015
- Place of Presentation
  奈良県新公会堂（奈良市）
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290028
[Presentation] 血管内皮タンパク質アルギニンメチル基転移酵素・PRMT1の機能解析2015
- Author(s)
  石丸友博、石田純治、金俊達、橋本美涼、水上早瀬、杉山文博、八神健一、深水昭吉
- Organizer
  第6回 Molecular Cardiovascular Conference Ⅱ
- Place of Presentation
  ヒルトン福岡シーホーク（福岡県、福岡市）
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] 血管内皮におけるタンパク質アルギニンメチル基転移酵素・PRMT1の機能解析2015
- Author(s)
  石丸友博、石田純治、金　俊達、仲島由佳、橋本美涼、水上早瀬、杉山文博、八神健一、深水昭吉
- Organizer
  第51回　高血圧関連疾患モデル学会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府、豊中市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] 血管内皮タンパク質アルギニンメチル基転移酵素・PRMT1の機能解析2015
- Author(s)
  石丸友博、石田純治、金　俊達、仲島由佳、橋本美涼、水上早瀬、杉山文博、八神健一、深水昭吉
- Organizer
  第19回　日本心血管内分泌代謝学
- Place of Presentation
  神戸国際会議場、兵庫県神戸市
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-25252062
[Presentation] 早期胚発生致死を示すWS変異マウスにおける原因遺伝子の同定2015
- Author(s)
  水野聖哉、高見幸平、飯島沙織、加藤花名子、大徳陽子、谷本陽子、杉山文博、八神健一
- Organizer
  実験動物学会
- Place of Presentation
  京都テルサ
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26870077
[Presentation] 血管内皮におけるタンパク質アルギニンメチル基転移酵素・PRMT1の機能解析2015
- Author(s)
  石丸友博、石田純治、金　俊達、仲島由佳、橋本美涼、水上早瀬、杉山文博、八神健一、深水昭吉
- Organizer
  第51回高血圧関連疾患モデル学会
- Place of Presentation
  千里ライフサイエンスセンター、大阪府豊中市
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-25252062
[Presentation] 血管内皮タンパク質アルギニンメチル基転移酵素・PRMT1の機能解析2015
- Author(s)
  石丸　友博、石田　純治、金　俊達、仲島　由佳、橋本　美涼、水上　早瀬、杉山　文博、八神　健一、深水　昭吉
- Organizer
  第19回　日本心血管内分泌代謝学
- Place of Presentation
  神戸国際会議場（兵庫県、神戸市）
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] Applied Genome Editing with CRISPR/Cas9 Plasmid in Mice2015
- Author(s)
  Seiya Mizuno, Kanako Kato, Saori Iijima, Yuko Hamada, Tra Dinh Thi Huong, Yoshikazu Hoshino, Yoko Tanimoto, Satoru Takahashi, Fumihiro Sugiyama, Ken-ichi Yagami
- Organizer
  トランスポゾン転移とゲノム編集技術に関する国際会議2015
- Place of Presentation
  奈良県新公会堂
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870077
[Presentation] 妊娠高血圧マウスに対する複数の降圧剤投与による病態の改善効果2015
- Author(s)
  権　哲源、石田純治、石丸友博、Haojun Xu、Baasanjav Altansarnai、水上早瀬、原加奈子、杉山文博、八神健一、深水昭吉
- Organizer
  第51回　高血圧関連疾患モデル学会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府、豊中市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] 早期胚発生致死を示すWS変異マウスにおける原因遺伝子の同定2015
- Author(s)
  水野聖哉、高見幸平、飯島沙織、加藤花名子、大徳陽子、谷本陽子、杉山文博、八神健一
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都テルサ（京都市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26290028
[Presentation] 妊娠高血圧マウスに対する複数の降圧剤投与による病態改善効果2014
- Author(s)
  石丸友博，石田純治，中村匠子、橋本美涼，松倉頼，Baasanjav Altansarnai，Haojun Xu，水上早瀬，権哲源，杉山文博，八神健一，深水昭吉
- Organizer
  第5回 Molecular cardiovascular conference II
- Place of Presentation
  神戸, 神戸ベイシェラトンホテル
- Year and Date
  2014-09-05
- Data Source
  KAKENHI-PROJECT-25252062
[Presentation] Vascular endothelial dysfunction in mice with pregnancy-associated hypertension2014
- Author(s)
  Tomohiro Ishimaru, Junji Ishida, Tanomu Matsukura, Katsumasa Nagano, Fumihiro Sugiyama, Ken-ichi Yagami, and Akiyoshi Fukamizu
- Organizer
  第18回国際血管生物学会
- Place of Presentation
  京都府, みやこめっせ
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PROJECT-25252062
[Presentation] Vascular endothelial dysfunction in mice with pregnancy-associated hypertension2014
- Author(s)
  Tomohiro Ishimaru, Junji Ishida, Tanomu Matsukura, Katsumasa Nagano, Fumihiro Sugiyama, Ken-ichi Yagami, and Akiyoshi Fukamizu
- Organizer
  International Vascular Biology Meeting 2014
- Place of Presentation
  みやこメッセ（京都府、京都市）
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] 妊娠高血圧マウスに対する複数の降圧剤投与による病態改善効果2014
- Author(s)
  石丸友博、石田純治、中村匠子、橋本美涼、松倉頼、Baasanjav Altansarnai、Haojun Xu、水上早瀬、権哲源、杉山文博、八神健一、深水昭吉
- Organizer
  5th Molecular cardiovascular conference II
- Place of Presentation
  神戸ベイシェラトンホテル（兵庫県、神戸市）
- Year and Date
  2014-09-05
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] EFFECT OF LACTATION ON POSTPARTUM CARDIAC FUNCTION OF PREGNANCY-ASSOCIATED HYPERTENSIVE MICE2014
- Author(s)
  Junji Ishida, Kazuya Murata, Chiaki Saito, Juri Hamada, Fumihiro Sugiyama, Ken-ichi Yagami, and Akiyoshi Fukamizu
- Organizer
  46th International Congress on Pathophysiology of Pregnancy
- Place of Presentation
  新宿京王プラザホテル（東京都、新宿区）
- Year and Date
  2014-09-19
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] Combinatorial treatment with antihypertensive drugs prevents HELLP syndrome exacerbated by endothelial dysfunction in pregnant hypertensive mice.2014
- Author(s)
  Junji Ishida, Tomohiro Ishimaru, Tanomu Matsukura, Shoko Nakamura, Haojun Xu, Altansarnai Baasanjav, Misuzu Hashimoto, Kazuya Murata, Katsumasa Nagano, Fumihiro Sugiyama, Ken-ichi Yagami, and Akiyoshi Fukamizu
- Organizer
  第18回国際血管生物学会
- Place of Presentation
  京都府, みやこめっせ
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PROJECT-25252062
[Presentation] Lactation causes cardiac contractile dysfunction in mice with pregnancy-associated hypertension2014
- Author(s)
  村田知弥、齊藤千明、石田純治、濱田樹理、杉山文博、　八神健一、深水昭吉
- Organizer
  第51回日本臨床分子医学会
- Place of Presentation
  東京国際フォーラム（東京都、千代田区）
- Year and Date
  2014-04-11
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] A role of p38 Mitogen-Activated Protein Kinase in Emphysema Induced by Cigarette Smoke Solution and Lipopolysaccharide in Mice2014
- Author(s)
  Hiroyuki Amano, Kazuya Murata, Hirofumi Matsunaga, Kensuke Tanaka, Takeshi Kobayashi, Junji Ishida, Akiyoshi Fukamizu, Fumihiro Sugiyama, Sadao Kimura, Koichiro Tatsumi, and Yoshitoshi Kasuya
- Organizer
  American Thoracic Society 2014
- Place of Presentation
  San Diego Convention Center, U.S.A.
- Year and Date
  2014-05-16
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] 妊娠高血圧マウスの病態発症・進展に対するAT1シグナル阻害効果の検討2014
- Author(s)
  石丸友博、石田純治、中村匠子、橋本美涼、松倉頼、中村あゆみ、Baasanjav Altansarnai、國田智、杉山文博、八神健一、深水昭吉
- Organizer
  第51回日本臨床分子医学会
- Place of Presentation
  東京国際フォーラム（東京都、千代田区）
- Year and Date
  2014-04-11
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] 妊娠高血圧マウスへの複数の降圧剤投与による病態改善効果の検討2014
- Author(s)
  石丸友博、石田純治、橋本美涼、Baasanjav Altansarnai、Xu Haojun、水上早瀬、権哲源、杉山文博、八神健一、深水昭吉
- Organizer
  第18回日本心血管内分泌代謝学会
- Place of Presentation
  横浜市開港記念会館（神奈川県、横浜市）
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] Combinatorial treatment with antihypertensive drugs prevents HELLP syndrome exacerbated by endothelial dysfunction in pregnant hypertensive mice.2014
- Author(s)
  Junji Ishida, Tomohiro Ishimaru, Tanomu Matsukura, Shoko Nakamura, Haojun Xu, Altansarnai Baasanjav, Misuzu Hashimoto, Kazuya Murata, Katsumasa Nagano, Fumihiro Sugiyama, Ken-ichi Yagami, and Akiyoshi Fukamizu
- Organizer
  International Vascular Biology Meeting 2014
- Place of Presentation
  みやこメッセ（京都府、京都市）
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PROJECT-26430086
[Presentation] Cre/loxP遺伝子組換え前後を異なる蛍光タンパク質でモニターするRosa26ノックインマウスC57BL/6Nマウス2013
- Author(s)
  大徳陽子、長谷川賀一、谷本陽子、村上亞弓、門田雅世、橋本知美、目加田和之、中田初美、吉木淳、三輪佳宏、依馬正次、水野聖哉、杉山文博、八神健一、高橋智
- Organizer
  実験動物学会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-21220009
[Presentation] ブレオマイシン誘導性間質性肺炎成立におけるp38MAPKの役割2010
- Author(s)
  粕谷善俊, 杉山文博, 松尾祐志, 並木香奈, 石田純治, 桑木共之, 須藤龍彦, 柴田さゆり, 萩原昌彦, 巽浩一郎, 深水昭吉, 木村定雄
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21390172
[Presentation] メタボリックシンドロームを発症するNZOマウスにおける制限給餌の効果2009
- Author(s)
  石毛太一郎, 西野入燈, 國田智, 杉山文博, 八神健一
- Organizer
  第56回日本実験動物学会総会
- Place of Presentation
  大宮ソニックシティ (埼玉県)
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-19300143
[Presentation] メタボリックシンドロームを発症するNZOマウスにおける制限給餌の効果2009
- Author(s)
  石毛太一郎、西野入燈、國田智、杉山文博、八神健一
- Organizer
  第56回日本実験動物学会総会
- Place of Presentation
  埼玉
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-19300143
[Presentation] メタボリックシンドロームを発症するNZOマウスにおける制限給餌の効果2009
- Author(s)
  石毛太一郎、西野入燈、國田智、杉山文博、八神健一
- Organizer
  第56回日本実験動物学会総会
- Place of Presentation
  大宮ソニックホシティ
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-19300143
[Presentation] (NZOxC3H)マウスにおける血圧量的遺伝子座解析2007
- Author(s)
  西原絵里、Tsaih SW、塚原千恵子、DiPetrillo K、Churchill GA、國田智、杉山文博、八神健一
- Organizer
  第54回日本実験動物学会
- Place of Presentation
  東京
- Year and Date
  2007-05-24
- Data Source
  KAKENHI-PROJECT-19300143
[Presentation] (NZOxC3H) マウスにおける血圧量的遺伝子座解析2007
- Author(s)
  西原絵里, Tsaih SW, 塚原千恵子, DiPetrillo K, Churchi GA, 國田智, 杉山文博, 八神健一
- Organizer
  第54回日本実験動物学会
- Place of Presentation
  タワーホール船堀 (東京都)
- Year and Date
  2007-05-24
- Data Source
  KAKENHI-PROJECT-19300143
[Presentation] A role of p38 mitogen-activated protein kinase in emphysema induced by cigarette smoke solution and lipopolysaccharide in Mice.
- Author(s)
  Amano H, Murata K, Matsunaga H, Tanaka K, Kobayashi T, Ishida J, Fukamizu A, Sugiyama F, Kimura S, Tatsumi K, Kasuya Y.
- Organizer
  American Thoracic Society (ATS) 2014 International Conference
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-24390137
[Presentation] CRISPR/Cas9プラスミドを介したマウスゲノム編集の応用
- Author(s)
  水野聖哉・加藤花名子・飯島沙織・Dinh Thi Huong Tra・谷本陽子・大徳陽子・石田みゆき・依馬正次・伊川正人・高橋智・杉山文博・八神健一
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26870077
[Presentation] Applied Genome Efiting with CRISPR/Cas9 Plasmid in Mice
- Author(s)
  水野聖哉・加藤花名子・飯島沙織・Dinh Thi Huong Tra・谷本陽子・大徳陽子・石田みゆき・高橋智・杉山文博・八神健一
- Organizer
  28th International Mammalian Genome Conference
- Place of Presentation
  バーハーバー（USA）
- Year and Date
  2014-10-26 – 2014-10-29
- Data Source
  KAKENHI-PROJECT-26290028
[Presentation] CRISPR/Cas9プラスミドを介したマウスゲノム編集の応用
- Author(s)
  水野聖哉・加藤花名子・飯島沙織・Dinh Thi Huong Tra・谷本陽子・大徳陽子・石田みゆき・依馬正次・伊川正人・高橋智・杉山文博・八神健一
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26290028
[Presentation] Applied Genome Efiting with CRISPR/Cas9 Plasmid in Mice
- Author(s)
  水野聖哉・加藤花名子・飯島沙織・Dinh Thi Huong Tra・谷本陽子・大徳陽子・石田みゆき・高橋智・杉山文博・八神健一
- Organizer
  28th International Mammalian Genome Conference
- Place of Presentation
  アメリカメイン州
- Year and Date
  2014-10-26 – 2014-10-29
- Data Source
  KAKENHI-PROJECT-26870077

1. YAGAMI Ken-ichi (40166476)

# of Collaborated Projects: 14 results

# of Collaborated Products: 37 results
2. FUKAMIZU Akiyoshi (60199172)

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# of Collaborated Products: 14 results
3. MIZUNO Seiya (10633141)

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4. KASUYA Yoshitoshi (70221877)

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# of Collaborated Projects: 5 results

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6. SUDO Tatsuhiko (30260227)

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7. MURAKAMI Kazuo (70110517)

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8. TANIMOTO Keiji (90261776)

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25. FAN Jianglin (60272192)

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# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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41. 久野朗広 (60830122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. Iijima Saori

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
43. Dinh Thi Huong Tra

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 菅谷健

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. SUGAYA Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. NANGAKU Masaomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. HARA Kenshiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. KITADATE Yu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. SATO Takuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. UENO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. TAKADA Ritsuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. ISEKI Hiroyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
53. HIROMORI Youhei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 国田智

# of Collaborated Projects: 0 results

# of Collaborated Products: 13 results
55. 加藤秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 松阪泰二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. 伊川正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 高橋昭久

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
59. 井本正哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 上野直人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. 吉田松生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. 小川毅彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
63. 小林和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
64. 高田昌彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
65. 吉田進昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
66. 吉田稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
67. 武田洋幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
68. 高田慎治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
69. 小林悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
70. 大石久史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
71. 松田洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
72. 中西剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
73. 永瀬久光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sugiyama Fumihiro 杉山 文博

SUGIYAMA Fumihiro 杉山 文博

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Biological functions of alternative splicing on mouse gastrulationPrincipal InvestigatorOngoing

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Elucidation of the molecular mechanism to maintain hierarchical structure of vascular system and and tumour angiogenesisOngoing

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Development of mouse-non-human primate chimera analysis innovating evaluation methods of human pluripotent stem cellsPrincipal Investigator

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Development of bicistronic cre driver mice using CRISPR/Cas9Principal Investigator

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Development of rat ES cells carrying rat Nanog reporter genePrincipal Investigator

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Sugiyama Fumihiro 杉山文博

SUGIYAMA Fumihiro 杉山文博