Yomogida Shinichi 蓬田伸一

… Alternative Names

YOMOGIDA Sinnichi 蓬田伸一

YOMOGIDA Shinichi 蓬田伸一

蓬田伸一ヨモギダシンイチ

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Researcher Number	90250802
Other IDs
Affiliation (Current)	2025: 山形県立保健医療大学, 保健医療学部, 教授
Affiliation (based on the past Project Information) *help	2008 – 2010: 高崎健康福祉大学, 薬学部, 准教授 2006: Takasaki University of Health and Welfare, Department of Pharmacy, Associate Professor 1998 – 2005: 山形大学, 医学部, 助手 1995: 東北大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Applied pharmacology / General pharmacology / 医薬分子機能学 Except Principal Investigator General pharmacology / 応用薬理学・医療系薬学 / General pharmacology / Biological pharmacy
Keywords	Principal Investigator endothelin / dimer / receptor / 二量体 / 受容体 / エンドセリン / Gene expression / Rabbit / RNase protection assay / Endothelin Receptor … More / TAK-044 / positive inotropic effect / rabbit heart / cDNA cloning / endothelin receptor / ヒスタミン / 血管透過性 / 慢性炎症 / アレルギー炎症 … More Except Principal Investigator Caトランジェント / エンドセリン / Herg / プロテインキナーゼC / Na^+ / norepinephrine / ノルエピネフリン / クロストーク / Ca^<2+> sensitizers / エクオリン / Caセンシタイザー / アシドーシス / Na-Ca交換機構 / protein kinase C / protein kinase A / プロテインキナーゼA / Ca^<2+> exchanger / endothelin / force-frequency relationship / Ca^<2+> mobilizers / dog ventricular cardiomyocytes / mouse ventricular cardiomyocytes / Y-27632 / wortomannin / 哺乳類心室筋 / アンギオテンシンII / 収縮タンパクCa^<2+>感受性 / ミオシン軽鎖 / ワートマニン / Rhoキナーゼ / 単離心室筋細胞 / Ca^<2+>感受性 / Ca^<2+>動員機構 / Ca^<2+>トランジェント / Ca^<2+>交換機構 / 頻度・収縮関係 / Ca^<2+>モビライザー / Ca^<2+>センシタイザー / イヌ心室筋細胞 / マウス心室筋細胞 / Ca transient / Ca signal / cardiac contractility / endothelin-1 / crosstalk / 心筋細胞 / イヌ心室筋 / マウス心筋細胞 / Caシグナル / 心筋収縮 / エンドセリン-1 / oocyte / tandem / sixth transmembrane region / amino-terminal region / deactivation / 抗不整脈薬 / 卵母細胞 / タンデム / 第6膜貫通領域 / アミノ末端領域 / 脱活性化 / HERG / Downstream mechanism / Central mechanis / Upstream mechanism / UD-CG 212 Cl / OR-1896 / Levosimendan / Pimobendan / 収縮タンパク / 心筋収縮性 / ベータ受容体 / 心肥大 / 心不全 / 容量負荷心 / PDE III阻害作用 / UD-CG212Cl / OR1896 / レボシメンダン / 容量負荷モデル / cAMP / Indo-1 / 収縮タンパクCa感受性 / Caモビライザー / 心不全モデル / Positive inotropic effect / Protein kinase C / Rabbit ventricular myocytes / Increased Ca^<2+> sensitivity / Ca^<2+> transients / Intracellular alkalinization / Na^+-H^+ exchange / Na^+-Ca^<2+> exchange / L型Ca電流 / ウサギ心室筋細胞 / KB-R7943 / Ethylisopropylamiloride / Ca交換機構 / H交換機構 / Na / アンジオテンシンII / 陽性変力作用 / 心室筋細胞、ウサギ / Ca感受性増強 / 細胞内アルカリ化 / Na-H交換機構 / tyrosine kinase / phosphorylation / human cardiac delayed rectifier / PYK2 / 共発現系 / K^+チャネル / チロシンキナーゼ / リン酸化 / ヒト心筋遅延整流型K^+チャネル / プロモーター解析 / 炎症性サイトカイン / P2受容体 / HIF-1α / Akt / PI3-キナーゼ / HMG-CoA還元酵素阻害剤 / 遺伝子発現 / CD39 / 細胞外ヌクレオチド代謝 / 血管内皮細胞 / 細胞内情報伝達 / 病態生理 / 炎症 / 心血管 Less

Basic study for development of a novel therapeutic strategy, targeting the extracellular ATP hydrolyzing enzyme, CD39 to protect from vascular endothelial disorder.
- Principal Investigator
  
  MATSUOKA Isao
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Takasaki University of Health and Welfare
Influence of forced multimerized receptor formation on the signal transduction mechanismsPrincipal Investigator
- Principal Investigator
  
  YOMOGIDA Shin-Ichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Takasaki University of Health and Welfare
  Yamagata University
Molecular pharmacological research for regulation and disorder of cardiac myocytes
- Principal Investigator
  
  ENDOH Masao
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yamagata University
Basic research for regulation and disorder of cardiac Ca signal
- Principal Investigator
  
  ENDOH Masao
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Yamagata University
Molecular mechanisms of the slow deactivation of HERG channel
- Principal Investigator
  
  ISHII Kuniaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Yamagata University
MORECULAR PHARMACOLOGICAL STUDY OF SIGNAL TRANSDUCTION
- Principal Investigator
  
  ENDOH Masao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  YAMAGATA UNIVERSITY SCHOOL OF MEDICINE
Development of Novel Therapeutic Agents for Treatment of Congestive Heart Failure by Means of Model Animals
- Principal Investigator
  
  ENDOH Masao
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Yamagata University
ウサギ心臓におけるエンドセリン受容体の特異性の解析Principal Investigator
- Principal Investigator
  
  蓬田伸一
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General pharmacology
- Research Institution
  Yamagata University
Involvement of tyrosine kinase in regulation of ion channel functions and crosstalk between signal transduction systems
- Principal Investigator
  
  ISHII Kuniaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yamagata University
アレルギー性炎症の慢性化及び再燃にかかわる血管透過性亢進因子の解析に関する研究Principal Investigator
- Principal Investigator
  
  蓬田伸一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Tohoku University

All 2010 2009 2008 2007 2004

All Journal Article Presentation

[Journal Article] Selective inhibition by wortmannin of the increase in Ca^<2+> sensitivity induced by crosstalk of endothelin-1 with norepinephrine in canine ventricular myocardium.2007
- Author(s)
  Chu, L., Norota, I., Yomogida, S., Ishii, K., Endoh, M.
- Journal Title
  
  Am.J.Physiol. (in preparation)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390064
[Journal Article] Differential inhibition by TAK-044 of the inotropic effects of endothelin-1 and endothelin-3.2004
- Author(s)
  Yomogida, S.
- Journal Title
  
  Eur.J.Pharmacol 492
  
  Pages: 217-224
- Data Source
  KAKENHI-PROJECT-16390064
[Journal Article] Differential inhibition by TAK-044 of the inotorpic effects of endothelin-1 and endothelin-3.2004
- Author(s)
  Yomogida, S.
- Journal Title
  
  Eur. J. Pharmacol. 492
  
  Pages: 217-224
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390064
[Journal Article] Differential inotropic effects of endothelin-1, angiotensin II, and phenylephrine induced by crosstalk with cAMP-mediated signaling process in dog ventricular myocardium.2004
- Author(s)
  Chu, L., Norota, I., Yomogida, S., Ishii, K., Endoh, M.
- Journal Title
  
  J.Pharmacol.Sci. 96
  
  Pages: 199-207
- NAID
  10014166837
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390064
[Journal Article] Differential inhibition by TAK-044 of the inotorpic effects of endothelin-1 and endothelin-3.2004
- Author(s)
  Yomogida, S., Maruya, J., Norota, I., Ishii, K., Endoh, M.
- Journal Title
  
  Eur.J.Pharmacol. 492
  
  Pages: 217-224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390064
[Presentation] HEK293細胞における細胞外ATP合成酵素の性質について2010
- Author(s)
  伊藤政明、蓬田伸一、松岡功
- Organizer
  第122回日本薬理学会関東部会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590088
[Presentation] Effects of HMG-CoA reductase inhibitors on vascular endothelial ecto-nucleotidase activities.2010
- Author(s)
  松岡功, 伊藤政明, 蓬田伸一
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590088
[Presentation] Effects of HMG-CoA reductase inhibitors on vascular endothelial ecto-nucleotidase activities2010
- Author(s)
  Matsuoka I, Ito M, Yomogida S
- Organizer
  第83回日本薬理学会年年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20590088
[Presentation] Regulation of isoprenyl transferase activity by signals from heterotrimeric G protein-coupled receptors2009
- Author(s)
  Matsuoka I, Ito M, Yomogida S
- Organizer
  The XXXVI international congress of Physiological Sciences
- Place of Presentation
  京都
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-20590088
[Presentation] Regulation of isoprenyl transferase activity by signals from heterotrimeric G protein-coupled receptors.2009
- Author(s)
  松岡功, 伊藤政明、蓬田伸一
- Organizer
  The XXXVI international congress of Physiological Sciences
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590088
[Presentation] ATP受容体を介する細胞応答における細胞外ATP分解酵素Nucleotide triphosphate diphosphohydrolase 1の役割2008
- Author(s)
  松岡功、伊藤政明、蓬田伸一
- Organizer
  第118回日本薬理学会関東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590088
[Presentation] ATP受容体を介する細胞応答における細胞外ATP分解酵素Nucleotide triphosphate diphosphohydrolaseの役割2008
- Author(s)
  松岡功, 伊藤政明, 蓬田伸一
- Organizer
  第118回日本薬理学会関東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590088

1. ENDOH Masao (40004668)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
2. ISHII Kuniaki (10184459)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
3. MATSUOKA Isao (10145633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. HOSOYA Yukio (10250945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YOMOGIDA Shin-ichi (90292440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TOMOIKE Hitonobu (90112333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NISHIMARU Kazuhide (60361250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yomogida Shinichi 蓬田 伸一

YOMOGIDA Sinnichi 蓬田 伸一

YOMOGIDA Shinichi 蓬田 伸一

蓬田 伸一 ヨモギダ シンイチ

Research Projects

Research Products

Co-Researchers

Basic study for development of a novel therapeutic strategy, targeting the extracellular ATP hydrolyzing enzyme, CD39 to protect from vascular endothelial disorder.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Influence of forced multimerized receptor formation on the signal transduction mechanismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular pharmacological research for regulation and disorder of cardiac myocytes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research for regulation and disorder of cardiac Ca signal

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of the slow deactivation of HERG channel

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MORECULAR PHARMACOLOGICAL STUDY OF SIGNAL TRANSDUCTION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Novel Therapeutic Agents for Treatment of Congestive Heart Failure by Means of Model Animals

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ウサギ心臓におけるエンドセリン受容体の特異性の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of tyrosine kinase in regulation of ion channel functions and crosstalk between signal transduction systems

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アレルギー性炎症の慢性化及び再燃にかかわる血管透過性亢進因子の解析に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Selective inhibition by wortmannin of the increase in Ca^<2+> sensitivity induced by crosstalk of endothelin-1 with norepinephrine in canine ventricular myocardium.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Differential inhibition by TAK-044 of the inotropic effects of endothelin-1 and endothelin-3.2004

Author(s)

Journal Title

Data Source

[Journal Article] Differential inhibition by TAK-044 of the inotorpic effects of endothelin-1 and endothelin-3.2004

Author(s)

Journal Title

Description

Yomogida Shinichi 蓬田伸一

YOMOGIDA Sinnichi 蓬田伸一

YOMOGIDA Shinichi 蓬田伸一

蓬田伸一ヨモギダシンイチ