Hanazawa Toyoyuki 花澤豊行

… Alternative Names

HANAZAWA Toyoyuki 花澤豊行

花澤豊行ハナザワトヨユキ

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Researcher Number	90272327
Other IDs
External Links
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 千葉大学, 大学院医学研究院, 教授 2014 – 2018: 千葉大学, 大学院医学研究院, 准教授 2011 – 2015: 千葉大学, 医学(系)研究科(研究院), 准教授 2007 – 2011: 千葉大学, 大学院・医学研究院, 准教授 2006: Chiba University, Graduate School of Medicine, Professor, Associate Professor, 大学院医学研究院, 助教授 … More 2005: 千葉大学, 大学院・医学研究院, 講師 1998: 千葉大, 医学部附属病院, 助手 1997: 千葉大学, 医学部・付属病院, 助手 1995 – 1997: 千葉大学, 医学部, 助手 1996: 千葉大学, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology
Keywords	Principal Investigator マイクロRNA / 治療抵抗性 / 分子標的薬 / セツキシマブ / 頭頸部扁平上皮癌 / 癌抑制遺伝子 / ゲノム / 鼻粘膜 / 一酸化窒素合成酵素 / 一酸化窒素 … More / ecDNA / 融合遺伝子 / 染色体外DNA / 腺様嚢胞癌 / 免疫ゲノム解析 / 免疫チェックポイント阻害薬 / 腫瘍浸潤リンパ球 / 悪性黒色腫 / 重粒子線治療 / 主要組織適合抗原複合体クラスI(MHC-I) / インターフェロンγ / 粘膜型悪性黒色腫 / 腫瘍免疫 / 扁平上皮癌 / 頭頸部癌 / miR-99a-3p / 発現プロファイル / 機能性RNA / 分子ネットワーク / EGFR / 上皮成長因子受容体 / 治療効果予測因子 / がん / 上顎癌 / HDAC1 / miR-874 / 上顎洞癌 / microRNA / ニューロテンシン / マイクロアレイ / 癌 / 遺伝子解析 / 神経ペプチド / 下咽頭癌 / 鼻アレルギー / 翼口蓋神経節 / 血管運動性鼻炎 / 血液ガス交換 / 慢性副鼻腔炎 / アレルギー性鼻炎 … More Except Principal Investigator 頭頸部扁平上皮癌 / マイクロRNA / 機能性RNA / 癌抑制遺伝子 / 癌遺伝子 / 鼻粘膜過敏性 / マイクロＲＮＡ / 下咽頭癌 / 頭頚部扁平上皮癌 / Th2細胞 / アレルギー性鼻炎 / PDXモデル / 腺様嚢胞癌 / 唾液腺癌 / 初代培養細胞 / 単一細胞解析 / エピゲノム / 嗅神経芽細胞腫 / 癌関連線維芽細胞 / 細胞外小胞 / シークエンス / microRNA / シークセンス / 血清 / エクソソーム / 口腔癌 / 抗癌剤耐性 / 免疫沈降法 / H3K27ac / スーパーエンハンサー / 転写因子 / 転写調節領域 / シスプラチン / ATAC-sequence / 治療抵抗性 / 頭頸部扁平上皮癌細胞 / miR-99a-3p / miR-99a-5p / miR-199 / 細胞外マトリックス / MET / 癌抑制型マイクロRNA / upper respiratory infection / Th2 cell / Th1 cell / cedar pollinosis / allergic rhintis / ウイルス / 気道感染 / 上気道感染 / Th1細胞 / スギ花粉症 / Neurotransmitter / Cytokine / Ehemical Mediater / Parasympathetic Reflex / Axon Reflex / Allergic Inflammation / Nasal Hyperreactivity / Nasal Allergy / 鼻粘膜知覚 / コラーゲン / ヒスタミンレセプター / サイトカイン / non-adrenergic,non-cholinergic(NANC)神経 / アレルギー / RANTES / H_1受容体 / 好酸球 / 女性ホルモン / 副交感神経反射 / 鼻粘膜上皮細胞 / 鼻粘膜腫脹 / 素因 / 副交感神経 / 交感神経 / 鼻粘膜過敏症 / 好酸球活性化 / 化学伝達物質 / 知覚神経 / 自律神経 / アレルギー性炎症 / 血管運動性鼻炎 / 鼻アレルギー / 鼻過敏症 / ｍｉｃｒｏＲＮＡ / がん抑制遺伝子 / CDK6 / miR-504 / 扁平上皮癌 / ゲノム / 転移 / 分子ネットワーク / 頭頸部癌 / 発現プロファイル / 機能性核酸 / 癌 / Th2サイトカイン / NKT細胞 / Th2 細胞 / Th2 サイトカイン / NKT 細胞 / 好酸球性副鼻腔炎 Less

Elucidation of molecular mechanisms of ecDNA-mediated resistance acquisition in rare cancers and development of novel therapeutic targetsPrincipal Investigator
- Principal Investigator
  
  花澤豊行
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
嗅神経芽細胞腫における高悪性度獲得メカニズムの解明と革新的新規治療法の開発
- Principal Investigator
  
  山崎一樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
患者由来細胞を用いた頭頸部腺様嚢胞癌における遺伝子変異の機能的意義の解明
- Principal Investigator
  
  福本一郎
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
頭頸部扁平上皮癌・スーパーエンハンサー解析に基づく抗癌剤耐性機構の解明
- Principal Investigator
  
  吉川直子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
細胞外小胞を介した口腔扁平上皮癌細胞の悪性化能獲得機構の解明
- Principal Investigator
  
  木下崇
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba Cancer Center (Research Institute)
Analysis of the immuno-genome and the effects of heavy ion therapy on mucosal melanoma of the nasal cavity and paranasal sinusesPrincipal Investigator
- Principal Investigator
  
  Hanazawa Toyoyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
Drug repositioning strategy of head and neck squamous cell carcinoma after treatment failure based on microRNA analysis
- Principal Investigator
  
  Kikkawa Naoko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
Identification of drug-resistance related RNA networks in head and neck squamous cell carcinoma cellsPrincipal Investigator
- Principal Investigator
  
  HANAZAWA TOYOYUKI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Elucidation of the extracellular matrix signal mechanism controled by tumor suppressor microRNAs in head and neck cancer
- Principal Investigator
  
  Ichiro Fukumoto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Southen Tohoku Research Institute for Neuroscience
  Chiba University
Investigation into the predictor of cetuximab effect based on microRNA in head and neck squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  Hanazawa Toyoyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Development of new therapeutic strategies of hypopharyngeal cancer based on the RNA network analysis
- Principal Investigator
  
  KIKKAWA Naoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Identification of tumor-suppressive microRNAs regulating metastatic pathways in HNSCC
- Principal Investigator
  
  SEKI Naohiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Identification of tumor suppressive nucleic acid medicine in maxillary sinus squamous cell carcionmaPrincipal Investigator
- Principal Investigator
  
  HANAZAWA Toyoyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Identification of differentially expressed microRNAs in head and neck squamous cell carcinoma based on microRNA expression signature
- Principal Investigator
  
  SEKI Naohiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Role of Neuropeptide Signals Induced Metastasis of Hypopharyngeal CancerPrincipal Investigator
- Principal Investigator
  
  HANAZAWA Toyoyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Role of NKT cells in the eosinophilic diseases in upper respiratory tract and approachfor a new treatment
- Principal Investigator
  
  OKAMOTO Yoshitaka
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Role of infectious diseases in allergic rhinitis
- Principal Investigator
  
  OKAMOTO Yoshitaka
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
血管作動性物質による鼻粘膜肥厚発生機序の解明Principal Investigator
- Principal Investigator
  
  花澤豊行
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
血管運動性鼻炎の病態解明-一酸化窒素の関与について-Principal Investigator
- Principal Investigator
  
  花澤豊行
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
鼻粘膜より産生される一酸化窒素の産生由来と機能的意義の解明Principal Investigator
- Principal Investigator
  
  花澤豊行
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Mechanism of development of nasal hyperreactivity
- Principal Investigator
  
  KONNO Akiyoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University

[Journal Article] High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects2023
- Author(s)
  Kawase K、Kawashima S、Nagasaki J、Inozume T、Tanji E、Kawazu M、Hanazawa T、Togashi Y
- Journal Title
  
  Cancer Immunology Research
  
  Volume: In press Issue: 7 Pages: 895-908
- DOI
  10.1158/2326-6066.cir-22-0815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-23K15261, KAKENHI-PROJECT-22K08424, KAKENHI-PROJECT-21K09625, KAKENHI-PROJECT-22K19459, KAKENHI-PROJECT-22K20824, KAKENHI-PROJECT-21H02772
[Journal Article] Impact of miR-1/miR-133 Clustered miRNAs: PFN2 Facilitates Malignant Phenotypes in Head and Neck Squamous Cell Carcinoma2022
- Author(s)
  Asai Shunichi、Koma Ayaka、Nohata Nijiro、Kinoshita Takashi、Kikkawa Naoko、Kato Mayuko、Minemura Chikashi、Uzawa Katsuhiro、Hanazawa Toyoyuki、Seki Naohiko
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 3 Pages: 663-663
- DOI
  10.3390/biomedicines10030663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09863, KAKENHI-PROJECT-19K18759, KAKENHI-PROJECT-21K09577
[Journal Article] PD-1 blockade therapy promotes infiltration of tumor-attacking exhausted T cell clonotypes2022
- Author(s)
  Nagasaki Joji、Inozume Takashi、Yosuke Togashi et al.
- Journal Title
  
  Cell Reports
  
  Volume: 38 Issue: 5 Pages: 110331-110331
- DOI
  10.1016/j.celrep.2022.110331
- NAID
  120007192058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21K07112, KAKENHI-PROJECT-21K08152, KAKENHI-PROJECT-21K08314, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-21K09625, KAKENHI-PROJECT-22K08424, KAKENHI-PROJECT-22H00455
[Journal Article] Identification of Antitumor miR-30e-5p Controlled Genes; Diagnostic and Prognostic Biomarkers for Head and Neck Squamous Cell Carcinoma2022
- Author(s)
  Chikashi Minemura, Shunichi Asai, Ayaka Koma, Naoko Kikkawa, Mayuko Kato, Atsushi Kasamatsu, Katsuhiro Uzawa, Toyoyuki Hanazawa, Naohiko Seki
- Journal Title
  
  Genes(Basel)
  
  Volume: 13 Issue: 7 Pages: 1-21
- DOI
  10.3390/genes13071225
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09367, KAKENHI-PROJECT-21K09577, KAKENHI-PROJECT-22K09679
[Journal Article] Genome-Wide Super-Enhancer-Based Analysis: Identification of Prognostic Genes in Oral Squamous Cell Carcinoma2022
- Author(s)
  Saito Tomoaki、Asai Shunichi、Tanaka Nozomi、Nohata Nijiro、Minemura Chikashi、Koma Ayaka、Kikkawa Naoko、Kasamatsu Atsushi、Hanazawa Toyoyuki、Uzawa Katsuhiro、Seki Naohiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 16 Pages: 9154-9154
- DOI
  10.3390/ijms23169154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09577, KAKENHI-PROJECT-22K09679, KAKENHI-PROJECT-20H03883
[Journal Article] Identification of miR-199-5p and miR-199-3p Target Genes: Paxillin Facilities Cancer Cell Aggressiveness in Head and Neck Squamous Cell Carcinoma2021
- Author(s)
  Tanaka Nozomi、Minemura Chikashi、Asai Shunichi、Kikkawa Naoko、Kinoshita Takashi、Oshima Sachi、Koma Ayaka、Kasamatsu Atsushi、Hanazawa Toyoyuki、Uzawa Katsuhiro、Seki Naohiko
- Journal Title
  
  Genes
  
  Volume: 12 Issue: 12 Pages: 1910-1910
- DOI
  10.3390/genes12121910
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09863, KAKENHI-PROJECT-19K18759, KAKENHI-PROJECT-21K09577
[Journal Article] ニボルマブを使用した再発・転移性頭頸部癌44例の検討2021
- Author(s)
  川瀬勝隆、越塚慶一、米田理葉、山﨑一樹、米倉修二、花澤豊行
- Journal Title
  
  頭頸部癌
  
  Volume: 47 Pages: 284-289
- NAID
  130008114711
- Data Source
  KAKENHI-PROJECT-21K09625
[Journal Article] Impact of Oncogenic Targets by Tumor-Suppressive miR-139-5p and miR-139-3p Regulation in Head and Neck Squamous Cell Carcinoma2021
- Author(s)
  Koma Ayaka、Asai Shunichi、Minemura Chikashi、Oshima Sachi、Kinoshita Takashi、Kikkawa Naoko、Koshizuka Keiichi、Moriya Shogo、Kasamatsu Atsushi、Hanazawa Toyoyuki、Uzawa Katsuhiro、Seki Naohiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 18 Pages: 9947-9947
- DOI
  10.3390/ijms22189947
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09863, KAKENHI-PROJECT-19K18759, KAKENHI-PROJECT-21K09577
[Journal Article] Toxic epidermal necrolysis associated with nivolumab treatment for head and neck cancer2020
- Author(s)
  Koshizuka K, Sakurai D, Sunagane M, Mita Y, Hamasaki S, Suzuki T, Kikkawa N, Nakano M, Hanazawa T.
- Journal Title
  
  Clin Case Rep.
  
  Volume: 9 Issue: 2 Pages: 848-852
- DOI
  10.1002/ccr3.3695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09863
[Journal Article] Regulation of Oncogenic Targets by miR-99a-3p (Passenger Strand of miR-99a-Duplex) in Head and Neck Squamous Cell Carcinoma2019
- Author(s)
  Okada Reona、Koshizuka Keiichi、Yamada Yasutaka、Moriya Shogo、Kikkawa Naoko、Kinoshita Takashi、Hanazawa Toyoyuki、Seki Naohiko
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 12 Pages: 1535-1535
- DOI
  10.3390/cells8121535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09338, KAKENHI-PROJECT-19K18759, KAKENHI-PROJECT-19K18795, KAKENHI-PROJECT-17K11375
[Journal Article] Dual-receptor (EGFR and c-MET) inhibition by tumor-suppressive miR-1 and miR-206 in head and neck squamous cell carcinoma.2017
- Author(s)
  Koshizuka K, Hanazawa T, Fukumoto I, Kikkawa N, Matsushita R, Mataki H, Mizuno K, Okamoto Y, Seki N.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 62 Issue: 1 Pages: 113-121
- DOI
  10.1038/jhg.2016.47
- NAID
  40021036343
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26462596, KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K11224
[Journal Article] Deep sequencing-based microRNA expression signatures in head and neck squamous cell carcinoma: dual strands of pre-miR-150 as antitumor miRNAs.2017
- Author(s)
  Koshizuka K, Hanazawa T, Fukumoto I, Kikkawa N, Okamoto Y, Seki N.
- Journal Title
  
  Oncotarget
  
  Volume: 印刷中 Issue: 18 Pages: 30288-30304
- DOI
  10.18632/oncotarget.16327
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K20229
[Journal Article] The microRNA signatures: aberrantly expressed microRNAs in head and neck squamous cell carcinoma.2017
- Author(s)
  Keiichi Koshizuka, Toyoyuki Hanazawa, Ichiro Fukumoto, Naoko Kikkawa, Yoshitaka Okamoto, Naohiko Seki.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 62 Issue: 1 Pages: 3-13
- DOI
  10.1038/jhg.2016.105
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-15K10800
[Journal Article] Regulation of ITGA3 by the anti-tumor miR-199 family inhibits cancer cell migration and invasion in head and neck cancer2017
- Author(s)
  Koshizuka Keiichi、Hanazawa Toyoyuki、Kikkawa Naoko、Arai Takayuki、Okato Atsushi、Kurozumi Akira、Kato Mayuko、Katada Koji、Okamoto Yoshitaka、Seki Naohiko
- Journal Title
  
  Cancer Science
  
  Volume: 108 Issue: 8 Pages: 1681-1692
- DOI
  10.1111/cas.13298
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K20229
[Journal Article] Antitumor miR-150-5p and miR-150-3p inhibit cancer cell aggressiveness by targeting SPOCK1 in head and neck squamous cell carcinoma.2017
- Author(s)
  Koshizuka, K., T. Hanazawa, N. Kikkawa, K. Katada, A. Okato, T. Arai, T. Idichi, Y. Osako, Y. Okamoto and N. Seki
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: - Issue: 4 Pages: 854-865
- DOI
  10.1016/j.anl.2017.11.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-18K09338, KAKENHI-PROJECT-17K16778
[Journal Article] Involvement of aberrantly expressed microRNAs in the pathogenesis of head and neck squamous cell carcinoma2017
- Author(s)
  Koshizuka Keiichi、Hanazawa Toyoyuki、Arai Takayuki、Okato Atsushi、Kikkawa Naoko、Seki Naohiko
- Journal Title
  
  Cancer Metastasis Rev
  
  Volume: 36 Issue: 3 Pages: 525-545
- DOI
  10.1007/s10555-017-9692-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-17K16893
[Journal Article] The tumor-suppressive microRNA-23b/27b cluster regulates the MET oncogene in oral squamous cell carcinoma.2016
- Author(s)
  Fukumoto I, Koshizuka K, Hanazawa T, Kikkawa N, Matsushita R, Kurozumi A, Kato M, Okato A, Okamoto Y, Seki N.
- Journal Title
  
  Int J Oncol.
  
  Volume: 49（3） Issue: 3 Pages: 1119-29
- DOI
  10.3892/ijo.2016.3602
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26462596, KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K11224
[Journal Article] Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma2016
- Author(s)
  Ichiro Fukumoto, Naoko Kikkawa, Ryosuke Matsushita, Mayuko Kato, Akira Kurozumi, Rika Nishikawa, Yusuke Goto, Keiichi Koshizuka, Toyoyuki Hanazawa, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 61(2) Issue: 2 Pages: 109-118
- DOI
  10.1038/jhg.2015.120
- NAID
  40020742209
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-25462676, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26462596
[Journal Article] MicroRNA expression signature of oral squamous cell carcinoma: functional role of microRNA-26a/b in the modulation of novel cancer pathways.2015
- Author(s)
  Fukumoto I, Hanazawa T, Kinoshita T, Kikkawa N, Koshizuka K, Goto Y, Nishikawa R, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Br J Cancer
  
  Volume: 112 Issue: 5 Pages: 891-900
- DOI
  10.1038/bjc.2015.19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462676, KAKENHI-PROJECT-25861528, KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-26462596
[Journal Article] microRNA-504 inhibits cancer cell proliferation via targeting CDK6 in hypopharyngeal squamous cell carcinoma.2014
- Author(s)
  Kikkawa N, Kinoshita T, Nohata N, Hanazawa T, Yamamoto N, Fukumoto I, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Int J Oncol.
  
  Volume: 44(6) Issue: 6 Pages: 2085-92
- DOI
  10.3892/ijo.2014.2349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-25861528
[Journal Article] microRNA-504 inhibits cancer cell proliferation via targeting CDK6 in hypopharyngeal squamous cell carcinoma.2014
- Author(s)
  Kikkawa N, Kinoshita T, Nohata N, Hanazawa T, Yamamoto N, Fukumoto I, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Int J Oncol
  
  Volume: 44 Pages: 2085-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462676
[Journal Article] Identification of tumour suppressive microRNA-451a in hypopharyngeal squamous cell carcinoma based on microRNA expression signature2014
- Author(s)
  Fukumoto I, Kinoshita T, Hanazawa T, Kikkawa N, Chiyomaru T, Enokida H, Yamamoto N, Goto Y, Nishikawa R, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 111 Issue: 2 Pages: 386-394
- DOI
  10.1038/bjc.2014.293
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-25462676, KAKENHI-PROJECT-25861528
[Journal Article] Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma.2013
- Author(s)
  Nohata N, Hanazawa T, Kinoshita T, Inamine A, Kikkawa N, Itesako T, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Br J Cancer
  
  Volume: 108 Issue: 8 Pages: 1648-1658
- DOI
  10.1038/bjc.2013.122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592575, KAKENHI-PROJECT-25861528
[Journal Article] Tumour-suppressive microRNA-29s inhibit cancer cell migration and invasion by targeting laminin-integrin signalling in head and neck squamous cell carcinoma.2013
- Author(s)
  Kinoshita T, Nohata N, Hanazawa T, Kikkawa N, Yamamoto N, Yoshino H, Itesako T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Br J Cancer
  
  Volume: 109 Issue: 10 Pages: 2636-2645
- DOI
  10.1038/bjc.2013.607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-25670694, KAKENHI-PROJECT-25861528
[Journal Article] Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma2012
- Author(s)
  Kinoshita T, Nohata N, Watanabe-Takano H, Yoshino H, Hidaka H, Fujimura L, Fuse M, Yamasaki T, Enokida H, Nakagawa M, Hanazawa T, Okamoto Y, Seki N.
- Journal Title
  
  Int. J. Oncol
  
  Volume: (印刷中) Pages: 1770-8
- DOI
  10.3892/ijo.2012.1390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790688, KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-23790769
[Journal Article] The functional significance of microRNA-375 in human squamous cell carcinoma: aberrant expression and effects on cancer pathways.2012
- Author(s)
  Kinoshita T, Hanazawa T, Nohata N, Okamoto Y, Seki N
- Journal Title
  
  J Hum Genet.
  
  Volume: 57 Issue: 9 Pages: 556-63
- DOI
  10.1038/jhg.2012.75
- NAID
  10031056783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-24592590
[Journal Article] Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma.2012
- Author(s)
  Kinoshita T, Hanazawa T, Nohata N, Kikkawa N, Enokida H, Yoshino H, Yamasaki T, Hidaka H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Oncotarget
  
  Volume: 3 Pages: 1386-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505
[Journal Article] microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers.2012
- Author(s)
  Nohata N, Hanazawa T, Enokida H, Seki N
- Journal Title
  
  Oncotarget
  
  Volume: 3 Pages: 9-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505
[Journal Article] Tumor suppressive microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma.2012
- Author(s)
  Kinoshita T, Hanazawa T, et al.
- Journal Title
  
  Int J Oncol
  
  Volume: 40 Pages: 185-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505
[Journal Article] Tumor suppressive microRNA-133a regulates novel targets : moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma2012
- Author(s)
  Takashi Kinoshita
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume: 418 Issue: 2 Pages: 378-83
- DOI
  10.1016/j.bbrc.2012.01.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187, KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-23790769
[Journal Article] Tumor suppressive microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma2012
- Author(s)
  Kinoshita T, Nohata N, Yoshino H, Hanazawa T, Kikkawa N, Fujimura L, Chiyomaru T, Kawakami K, Enokida H, Nakagawa M, Okamoto Y, Seki N.
- Journal Title
  
  Int J Oncol
  
  Volume: 40 Pages: 185-93
- DOI
  10.3892/ijo.2011.1196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-23790769
[Journal Article] Caveolin-1 mediates tumor cell migration and invasion and its regulation by miR-133a in head and neck squamous cell carcinoma.2011
- Author(s)
  Nohata N, Hanazawa T, Kikkawa N, Mutallip M, Fujimura L, Yoshino H, Kawakami K, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N
- Journal Title
  
  Int J Oncol. 38(1)
  
  Pages: 209-217
- Data Source
  KAKENHI-PROJECT-20592011
[Journal Article] Identification of novel molecular targets regulated by tumor suppressive miR-1/miR-133a in maxillary sinus squamous cell carcinoma2011
- Author(s)
  Nohata N, Hanazawa T, Kikkawa N, Sakurai D, Sasaki K, Chiyomaru T, Kawakami K, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N
- Journal Title
  
  Int J Oncol
  
  Volume: 39 Pages: 1099-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] Tumour suppressive microRNA-874 regulates novel cancer networks in maxillary sinus squamous cell carcinoma.2011
- Author(s)
  Nohata N, Hanazawa T, et al.
- Journal Title
  
  Br J Cancer
  
  Volume: 105 Pages: 833-841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592505
[Journal Article] Caveolin-1 mediates tumor cell migration and invasion and its regulation by miR-133a in head and neck squamous cell carcinoma2011
- Author(s)
  Nohata N, Hanazawa T, Kikkawa N, Mutallip M, Fujimura L, Yoshino H, Kawakami K, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N
- Journal Title
  
  Int J Oncol
  
  Volume: 38 Pages: 209-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma2011
- Author(s)
  Nohata N, Sone Y, Hanazawa T, Fuse M, Kikkawa N, Yoshino H, Chiyomaru T, Kawakami K, Enokida H, Nakagawa M, Shozu M, Okamoto Y, Seki N
- Journal Title
  
  Oncotarget
  
  Volume: 2 Pages: 29-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] Tumour suppressive microRNA-874 regulates novel cancer networks in maxillary sinus squamous cell carcinoma2011
- Author(s)
  Nijiro Nohata
- Journal Title
  
  British journal of cancer
  
  Volume: 105 Issue: 6 Pages: 833-41
- DOI
  10.1038/bjc.2011.311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187, KAKENHI-PROJECT-23592505
[Journal Article] Tumour suppressive microRNA-874 regulates novel cancer networks in maxillary sinus squamous cell carcinoma2011
- Author(s)
  Nohata N, Hanazawa T, Kikkawa N, Sakurai D, Fujimura L, Chiyomaru T, Kawakami K, Yoshino H, Enokida H, Nakagawa M, Katayama A, Harabuchi Y, Okamoto Y, Seki N
- Journal Title
  
  Br J Cancer
  
  Volume: 105 Pages: 833-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC)2011
- Author(s)
  Nohata N, Hanazawa T, Kikkawa N, Mutallip M, Sakurai D, Fujimura L, Kawakami K, Chiyomaru T, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N
- Journal Title
  
  J Hum Genet
  
  Volume: 56 Pages: 595-601
- NAID
  40018947302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] Identification of novel molecular targets regulated by tumor suppressive miR-1/miR-133a in maxillary sinus squamous cell carcinoma2011
- Author(s)
  Nijiro Nohata
- Journal Title
  
  International journal of oncology
  
  Volume: 39 Pages: 1099-107
- DOI
  10.3892/ijo.2011.1096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187, KAKENHI-PROJECT-23592505
[Journal Article] miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC).2010
- Author(s)
  Kikkawa N, Hanazawa T, Fujimura L, Nohata N, Suzuki H, Chazono H, Sakurai D, Horiguchi S, Okamoto Y, Seki N.
- Journal Title
  
  Br J Cancer. 7;103(6)
  
  Pages: 877-884
- Data Source
  KAKENHI-PROJECT-20592011
[Journal Article] マイクロRNA(miR-l45、miR-133a・b)の頭頸部扁平上皮癌における増殖・浸潤抑制機能と標的遺伝子の同定2010
- Author(s)
  花澤豊行
- Journal Title
  
  頭頸部癌
  
  Volume: 36 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592011
[Journal Article] miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC)2010
- Author(s)
  Kikkawa N, Hanazawa T, Fujimura L, Nohata N, Suzuki H, Chazono H, Sakurai D, Horiguchi S, Okamoto Y, Seki N
- Journal Title
  
  Br J Cancer
  
  Volume: 103 Pages: 877-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592187
[Journal Article] マイクロRNA(miR-145、miR-133a・b)の頭頸部扁平上皮癌における増殖・浸潤抑制機能と標的遺伝子の同定2010
- Author(s)
  花澤豊行, 吉川直子, 野畑二次郎, 堅田浩司, ムラディル・ムラリフ, 鈴木誉, 佐々木慶太, 茶薗英明, 堀口茂俊, 岡本美孝, 関直彦
- Journal Title
  
  頭頸部癌 36(1)
  
  Pages: 1-8
- NAID
  10029079202
- Data Source
  KAKENHI-PROJECT-20592011
[Journal Article] The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma.2009
- Author(s)
  Sugimoto T, Seki N, Shimizu S, Kikkawa N, Tsukada J, Shimada H, Sasaki K, Hanazawa T, Okamoto Y, Hata A
- Journal Title
  
  Genes Chromosomes Cancer. 48(2)
  
  Pages: 132-142
- Data Source
  KAKENHI-PROJECT-20592011
[Journal Article] Identification of a novel therapeutic target for head and neck squamous cell carcinomas : A role for the neurotensin-neurotensin receptor 1 oncogenic signaling pathway.2008
- Author(s)
  Shimizu S, Tsukada J, Sugimoto T, Kikkawa N, Sasaki K, Chazono H, Hanazawa T, Okamoto Y, Seki N
- Journal Title
  
  Int J Cancer. 15;123(8)
  
  Pages: 1816-1823
- Data Source
  KAKENHI-PROJECT-20592011
[Journal Article] Influence of viral infection on the development of nasal hypersensitivity2005
- Author(s)
  Y.Okamoto, Z.Matsuzaki, T.Matsuoka, S.Endo, H.Yamamoto, H.Chazono, S.Horiguchi, T.Hanazawa
- Journal Title
  
  Clinical and Experimental Allergy 35
  
  Pages: 679-684
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591776
[Journal Article] Present situation of cedar pollinosis in Japan and its immune responses
- Author(s)
  Okamoto Y, Horiguchi S, YamamotoH, YonekuraS, Hanazawa T.
- Journal Title
  
  Allergology International (in press)
- NAID
  10025109444
- Data Source
  KAKENHI-PROJECT-19591956
[Presentation] High major histocompatibility complex class I expression overcomes cancer immunotherapy resistance due to interferon gamma signaling pathway defects.2023
- Author(s)
  Kawase K, Kawashima S, Nagasaki J, Inozume T, Yamamoto H, Kawazu M, Hanazawa T, Togashi Y.
- Organizer
  AACR Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09625
[Presentation] Increasing MHC class I expression is crucial for antitumor immunity among IFNγ signaling pathways.2023
- Author(s)
  Kawase K, Kawashima S, Nagasaki J, Inozume T, Kawazu M, Hanazawa T, Togashi Y.
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K09625
[Presentation] ニボルマブを使用した再発・転移性頭頸部癌44例の検討2021
- Author(s)
  川瀬勝隆、越塚慶一、米田理葉、山﨑一樹、米倉修二、花澤豊行
- Organizer
  第45回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-21K09625
[Presentation] 2種類のマイクロRNA(miR-150-5p/-3p)が共通して制御する頭頸扁平上皮癌・癌抑制機構の探索2017
- Author(s)
  越塚慶一, 花澤豊行, 吉川直子, 福本一郎, 岡本美孝
- Organizer
  第41回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-17K11375
[Presentation] 頭頸部扁平上皮癌において癌抑制型miR-1/206はEGFRとc-METを制御する．2016
- Author(s)
  11.越塚慶一, 花澤豊行, 福本一郎, 吉川直子, 松下良介, 俣木浩子, 水野圭子, 岡本美孝, 関直彦．
- Organizer
  第75回日本癌学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26462596
[Presentation] 下咽頭癌における癌抑制型ｍｉｃｒｏＲＮＡ－５０４の機能解析と標的分子の探索2014
- Author(s)
  吉川直子　花澤豊行　木下崇　福本一郎　岡本美孝
- Organizer
  第115回　日本耳鼻咽喉科学会総会
- Place of Presentation
  ヒルトン福岡シーホーク（福岡県福岡市）
- Year and Date
  2014-05-16
- Data Source
  KAKENHI-PROJECT-25462676
[Presentation] 下咽頭癌においてｍｉＲ－５０４はＣＤＫ６の制御を介して細胞増殖を抑制する2014
- Author(s)
  吉川直子　花澤豊行　木下崇　福本一郎　岡本美孝　関直彦
- Organizer
  第38回　日本頭頸部癌学会
- Place of Presentation
  東京ファッションタウンビル（東京都江東区）
- Year and Date
  2014-06-12
- Data Source
  KAKENHI-PROJECT-25462676
[Presentation] Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma2013
- Author(s)
  Takashi Kinoshita, Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Noriko Yamamoto, Hideki Enokida, Hirofumi Yoshino, Takeshi Yamasaki, Hideo Hidaka, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  AACR Annual 104th Meeting
- Place of Presentation
  Washington, DC, USA)
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] microRNA-874 as a tumor suppressor in maxillary sinus squamous cell carcinoma based on microRNA expression signature2012
- Author(s)
  Toyoyuki Hanazawa, Nijiro Nohata, Takashi Kinoshita,Naoko Kikkawa,Miki Fuse, Takeshi Chiyomaru, Hirofumi Yoshinoi, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  AACR 103rd Annual Meeting
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] Tumor suppressive microRNA-1 and microRNA-133a cluster regulating molecular targets in head and neck squamous cell carcinoma2012
- Author(s)
  Nijiro Nohata, Toyoyuki Hanazawa, Takashi Kinoshita, Naoko Kikkawa, Daiju Sakurai, Miki Fuse, Hirofumi Yoshino, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  8th International Conference on Head and Neck Cancer
- Place of Presentation
  Toronto, ON, Canada
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] 癌抑制型microRNA-874が制御する頭頸部扁平上皮癌の新規分子ネットワークの解明2012
- Author(s)
  花澤豊行、野畑二次郎、木下崇、吉川直子、堅田浩司、茶薗英明、岡本美孝、関直彦
- Organizer
  第36回日本頭頸部癌学会
- Place of Presentation
  島根県民会館（島根）
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] 癌抑制型microRNA-874が制御する頭頸部扁平上皮癌の新規分子ネットワークの解明2012
- Author(s)
  花澤豊行、野畑二次郎、木下崇、吉川直子、堅田浩司、茶薗英明、岡本美孝、関直彦
- Organizer
  第36回日本頭頸部癌学会学術講演会
- Place of Presentation
  島根県民会館島根
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] 癌抑制型microRNA-375が制御する分子ネットワークの解明と頭頸部扁平上皮癌新規治療戦略の開発2012
- Author(s)
  花澤豊行、野畑二次郎、木下崇、吉川直子、鈴木誉、茶薗英明、櫻井大樹、岡本美孝
- Organizer
  第113回日本耳鼻咽喉科学会
- Place of Presentation
  朱鷺メッセ（新潟）
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] 癌抑制型microRNA-375が制御する分子ネットワークの解明と頭頸部扁平上皮癌新規治療戦略の開発2012
- Author(s)
  花澤豊行、野畑二次郎、木下崇、吉川直子、鈴木誉、茶薗英明、櫻井大樹、岡本美孝
- Organizer
  第113回日本耳鼻咽喉科学会学術講演会
- Place of Presentation
  朱鷺メッセ新潟
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] Identification of tumor suppressive microRNAs and their target genes in maxillary sinus squamous cell carcinoma2011
- Author(s)
  花澤豊行
- Organizer
  第11回日本台湾耳鼻咽喉科頭頸部外科学会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] Identification of tumor suppressive micro RNAs in maxillary sinus squamous cell carcinoma based on micro RNA expression signature2011
- Author(s)
  Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Akihiro Katayama, Yasuaki Harabuchi, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  AACR 102nd Annual Meeting
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-21592187
[Presentation] Tumor suppressive microRNA-375 targeting multiple oncogenes in maxillary sinus squamous cell carcinoma (MSSCC)2011
- Author(s)
  Takashi Kinoshita, Nijiro Nohata, Toyoyuki Hanazawa, Naoko Kikkawa, Mutallip Muradil, Hirofumi Yoshino, Kazumori Kawakami, Takeshi Chiyomaru, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場名古屋
- Data Source
  KAKENHI-PROJECT-21592187
[Presentation] Identification of tumor suppressive microRNAs in maxillary sinus squamous cell carcinoma based on microRNA expression signature2011
- Author(s)
  Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Akihiro Katayama, Yasuaki Harabuchi, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  AACR 102nd Annual Meeting
- Place of Presentation
  Orlando, Florida, USA
- Data Source
  KAKENHI-PROJECT-23592505
[Presentation] Tumor suppressive microRNA-1/-133a regulates multiple oncogenes in maxillary sinus squamous cell carcinoma2011
- Author(s)
  Nijiro Nohata, Toyoyuki Hanazawa, Takashi Kinoshita, Naoko Kikkawa, Muradil Mutallip, Takeshi Chiyomaru, Kazumori Kawakami, Hirofumi Yoshino, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
- Place of Presentation
  Rhodes Island, Greece
- Data Source
  KAKENHI-PROJECT-21592187
[Presentation] miR-133a as a tumor suppressive microRNA targeting multiple oncogenes in head neck squamous cell carcinoma2011
- Author(s)
  Nijiro Nohata, Toyoyuki Hanazawa, Naoko Kikkawa, Miki Fuse, Takeshi Chiyomaru, Kazumori Kawakami, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
- Organizer
  AACR 102nd Annual Meeting
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-21592187
[Presentation] miR-15a as potential therapeutic molecule for head and neck squamous cell carcinoma(HNSCC).2010
- Author(s)
  花澤豊行
- Organizer
  第101回アメリカ癌学会
- Place of Presentation
  ワシントンDC
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-20592011
[Presentation] miR-15a as potential therapeutic molecule for head and neck squamous cell carcinoma (HNSCC).2010
- Author(s)
  花澤豊行
- Organizer
  AACR101st
- Place of Presentation
  Washington DC
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-20592011
[Presentation] 血液中に存在するマイクロRNAを指標とした頭頸部扁平上皮癌診断マーカーの探索2009
- Author(s)
  花澤豊行
- Organizer
  日本癌学会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20592011
[Presentation] ゲノム解析に基づく頭頸部扁平上皮癌・分子標的の探索(1)ガラニンレセプターを介するシグナル伝達機構の解明2008
- Author(s)
  花澤豊行
- Organizer
  第32回日本頭頸部癌学会
- Place of Presentation
  東京
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-20592011
[Presentation] Neurotensin signaling pathway is a novel therapeutic target for head and neck squamous cell carcinomas2008
- Author(s)
  花澤豊行
- Organizer
  日本癌学会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20592011
[Presentation] ニューロテンシンシグナルによる頭頸部扁平上皮癌転移・浸潤機構の解明2008
- Author(s)
  花澤豊行
- Organizer
  第68回日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20592011
[]

1. SEKI Naohiko (50345013)

# of Collaborated Projects: 11 results

# of Collaborated Products: 47 results
2. KIKKAWA Naoko (50400924)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
3. HORIGUCHI Shigetoshi (30293468)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. OKAMOTO Yoshitaka (40169157)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. Ichiro Fukumoto (70748764)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. 中川拓也 (50813531)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KONNO Akiyoshi (70009497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NUMATA Tsutomu (60189355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAGATA Hiroshi (20237530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TERADA Nibuhisa (70197797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OKAWA Toru (40344981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 仲野公一 (50261920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 遊座潤 (40261929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 野本実 (70237890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 猪爪隆史 (80334853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. 冨樫庸介 (80758326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 木下崇 (00648462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 金田篤志 (10313024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 山崎一樹 (00422238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 河津正人 (20401078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 小林謙也 (80648311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 高野晴子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 越塚慶一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 加藤繭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hanazawa Toyoyuki 花澤 豊行

HANAZAWA Toyoyuki 花澤 豊行

花澤 豊行 ハナザワ トヨユキ

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Elucidation of molecular mechanisms of ecDNA-mediated resistance acquisition in rare cancers and development of novel therapeutic targetsPrincipal Investigator

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Analysis of the immuno-genome and the effects of heavy ion therapy on mucosal melanoma of the nasal cavity and paranasal sinusesPrincipal Investigator

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Identification of drug-resistance related RNA networks in head and neck squamous cell carcinoma cellsPrincipal Investigator

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Investigation into the predictor of cetuximab effect based on microRNA in head and neck squamous cell carcinomaPrincipal Investigator

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Identification of tumor suppressive nucleic acid medicine in maxillary sinus squamous cell carcionmaPrincipal Investigator

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Hanazawa Toyoyuki 花澤豊行

HANAZAWA Toyoyuki 花澤豊行

花澤豊行ハナザワトヨユキ