takuma kazuhiro 田熊一敞

… Alternative Names

TAKUMA Kazuhiro 田熊一敞

田熊一敞タクマカズヒロ

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Researcher Number	90289025
Other IDs	https://orcid.org/0000-0001-6484-1122
External Links
Affiliation (Current)	2024: 大阪大学, 大学院歯学研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪大学, 大学院歯学研究科, 教授 2021 – 2022: 大阪大学, 歯学研究科, 教授 2016 – 2018: 大阪大学, 歯学研究科, 教授 2015: 大阪大学, 大学院歯学研究科, 教授 2014 – 2015: 大阪大学, 歯学研究科(研究院), 教授 … More 2013: 大阪大学, 薬学研究科(研究院), 准教授 2013: 大阪大学, 薬学研究科, 准教授 2009 – 2010: 大阪大学, 大学院・薬学研究科, 准教授 2008 – 2010: Osaka University, 薬学研究科, 准教授 2007: Kanazawa University, Graduate School of Natural Science and Technology, Associate Professor 2004 – 2006: 金沢大学, 自然科学研究科, 助教授 1999 – 2003: 神戸学院大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Biological pharmacy / Biological pharmacy / Pharmacology in pharmacy / General pharmacology Except Principal Investigator Pharmacology in pharmacy / General pharmacology / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Medium-sized Section 57:Oral science and related fields / Basic Section 48010:Anatomy-related / Basic Section 57020:Oral pathobiological science-related / 医薬分子機能学 / Applied pharmacology
Keywords	Principal Investigator ミトコンドリア / アポトーシス / 活性酸素 / 遅発性細胞死 / アストロサイト / バルプロ酸 / 自閉スペクトラム症 / 発達障害 / RAGE / ABAD … More / アルツハイマー病 / ドパミン神経系 / オキシトシン / 社会性障害 / マウス / 性差 / 脳神経疾患 / 薬理学 / Resident-intruder試験 / Resident-Intruder試験 / 覚せい剤精神病 / 難治性うつ病 / 自閉症 / 樹状突起スパイン / 豊かな環境飼育 / 社会的相互作用試験 / エンカウンター試験 / 精神疾患 / apoptosis / mitochondria / β-amyloid / neuron cultures / Alzheimer's disease / 透過性遷移孔 / アミロイドβペプチド / β-アミロイド / 神経細胞 / 神経変性 / コリン作動性神経系 / 海馬 / エストロゲン / 更年期障害 / 細胞周期調節因子 / Permeability Transition Pore / Permeability Transition Pore (PTP) / ホスホジエステラーゼ / Gキナーゼ / 活性酵素 / NF-κB / MAPキナーゼ / 神経成長因子 / プロテアーゼ … More Except Principal Investigator free radical / lipid peroxidation / antioxidant / ubiquinone / 大脳皮質前頭前野 / 雌選択性試験 / 抗うつ薬 / ドパミン / 精神疾患 / 環境要因 / 認知症 / 抗甲状腺薬 / レポータートランスジェニックマウス / in vivoイメージング / 機能低下 / 睡眠 / 脳機能 / 吸啜 / 筋電図 / 発達 / 咀嚼 / 神経変性疾患 / 細胞死 / Tau蛋白質 / SUMO化修飾 / 小胞体ストレス / 糖尿病 / 細胞内ｃAMP / 骨髄間質幹細胞 / シングルセル解析 / 未分化間葉系幹細胞 / 機能亢進型GNAS変異疾患 / シグナル伝達異常 / 骨髄間質細胞 / 線維性骨異形成症 / 機能亢進型GNAS変異 / 前頭葉 / アンヘドニア / 腹側被蓋野 / c-Fos / 細胞内カルシウム / PC12細胞 / SH-SY5Y細胞 / 5-HT1A 受容体 / σ1受容体 / 抗不安作用 / 抗うつ作用 / 相互作用 / GABAA受容体 / 5-HT1A受容体 / シグマ1受容体 / mitochondira / ubiquinone analog / アストロサイト / 活性酸素 / 抗酸化作用 / ubiquinone amalog / ミトコンドリア / フリーラジカル / 脂質過酸化 / 抗酸化物質 / ユビキノン類縁体 / ユビキノン / モノアミン / グルタミン酸神経 / 長期隔離飼育マウス / 覚せい剤 / 環境因子 / 個体間相互作用 / エンカウンター刺激 / SEA0400 / Nitric oxide (NO) / Na+/Ca2+交換系(NCX) / 精神機能 / 細胞障害 / 一酸化窒素（NO） / 一酸化窒素 / Na+/Ca2+交換系 / エピジェネティクス / バルプロ酸 / 海馬 / ヒストン / PACAP遺伝子欠損マウス / エピジェネテクス / プロテインキナーゼA / ドーパミンD1受容体 / モルヒネ / メタンフェタミン / ニコチン / 覚せい剤精神病 / 薬物依存 / ドーパミン / プラスミン / 組織プラスミノーゲン活性化因子 Less

Basic research on suppressing the pathogenesis of autism spectrum disorder by targeting oxytocin neural networkPrincipal Investigator
- Principal Investigator
  
  田熊一敞
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka University
Refinement of the theory to evaluate developmental neurotoxicity of chemical substances that induce hypothyroidism
- Principal Investigator
  
  永瀬久光
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Gihu University of Medical Science
機能亢進型GNAS変異マウスを用いた線維性骨異形成症の病態解明と創薬展開
- Principal Investigator
  
  豊澤悟
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Osaka University
Clarification of the molecular pathogenesis of autism spectrum disorders through the analysis regarding sex differencesPrincipal Investigator
- Principal Investigator
  
  田熊一敞
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka University
糖尿病における小胞体ストレス応答とSUMO化
- Principal Investigator
  
  松崎伸介
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Morinomiya University of Medical Sciences
咀嚼機能発達低下動物モデルの口腔機能と脳発達特性の解明
- Principal Investigator
  
  加藤隆史
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Drug discovery research targeting the novel regulation of prefrontal dopaminergic system by the functional interaction between the sigma1 and serotonin1A receptors
- Principal Investigator
  
  AGO Yukio
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka University
Neurochemical study for cognitive behavioral therapy in mouse models of neuropsychiatric and neurodevelopmental disordersPrincipal Investigator
- Principal Investigator
  
  Takuma Kazuhiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka University
Drug discovery research targeting brain neurochemical signals responsible for induction of abnormal behaviors in mouse models of psychiatric disorders
- Principal Investigator
  
  AGO Yukio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka University
Study on pathophysiological roles of brain NO-NCX signal
- Principal Investigator
  
  MATSUDA Toshio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Osaka University
創薬を目指した環境要因誘発精神疾患動物でのエピジェネティクス研究
- Principal Investigator
  
  MATSUDA Toshio
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University
Molecular Analysis of cognitive impairment associated with postmenopausal memory loss and Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  TAKUMA Kazuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
ANALYSES OF DYNAMIC CHANGES AND THE FUNCTION OF TISSUE PLASMINOGEN ACTIVATOR IN ANIMAL MODELS OF DOPAMINE-RELATED MENTAL DISORDERS
- Principal Investigator
  
  YAMADA Kiyofumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Molecular mechanisms of mitochondrial dysfunction and neurotoxicity induced by Aβ-ARAD interactionPrincipal Investigator
- Principal Investigator
  
  TAKUMA Kazuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kanazawa University
グリア細胞アポトーシス発現におけるミトコンドリア蛋白の機能的役割Principal Investigator
- Principal Investigator
  
  田熊一浩
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kanazawa University
  Kobe Gakuin University
グリア細胞アポトーシスの発現機序とGキナーゼを介する制御機構の解析Principal Investigator
- Principal Investigator
  
  田熊一浩
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Gakuin University
Pharmaceutical activity of ubiquinone analogs
- Principal Investigator
  
  MORI Koichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kobe Gakuin University
グリア細胞アポトーシスにおけるプロテアーゼの役割に関する研究Principal Investigator
- Principal Investigator
  
  田熊一浩
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Gakuin University

[Journal Article] Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome2022
- Author(s)
  Takemoto Tomoya、Baba Masayuki、Yokoyama Kazumasa、Kitagawa Kohei、Nagayasu Kazuki、Ago Yukio、Seiriki Kaoru、Hayata-Takano Atsuko、Kasai Atsushi、Mori Daisuke、Ozaki Norio、Takuma Kazuhiro、Hashimoto Ryota、Hashimoto Hitoshi、Nakazawa Takanobu
- Journal Title
  
  Molecular Brain
  
  Volume: 15 Issue: 1 Pages: 26-26
- DOI
  10.1186/s13041-022-00915-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21464, KAKENHI-PROJECT-20H03556, KAKENHI-PROJECT-19H05467, KAKENHI-PLANNED-18H05416, KAKENHI-PUBLICLY-20H04774, KAKENHI-PUBLICLY-21H00213, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-21H02628, KAKENHI-PROJECT-21J15163, KAKENHI-PROJECT-21K19335, KAKENHI-PROJECT-21K06594, KAKENHI-PROJECT-22H04922
[Journal Article] Prenatal exposure to valproic acid causes allodynia associated with spinal microglial activation2022
- Author(s)
  Imado E, Sun S, Abawa AR, Tahara T, Kochi T, Huynh TNB, Asano S, Hasebe S, Nakamura Y, Hisaoka-Nakashima K, Kotake Y, Irifune M, Tsuga K, Takuma K, Morioka N, Kiguchi N, Ago Y.
- Journal Title
  
  Neurochemistry International
  
  Volume: 160 Pages: 105415-105415
- DOI
  10.1016/j.neuint.2022.105415
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06594, KAKENHI-PROJECT-21K10139, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20H04342, KAKENHI-PROJECT-20K09227, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714
[Journal Article] Small-molecule non-peptide antagonists of the PACAP receptor attenuate acute restraint stress-induced anxiety-like behaviors in mice2022
- Author(s)
  Shintani Yusuke、Hayata-Takano Atsuko、Yamano Yui、Ikuta Mankato、Takeuchi Rei、Takuma Kazuhiro、Okada Takuya、Toyooka Naoki、Takasaki Ichiro、Miyata Atsuro、Kurihara Takashi、Hashimoto Hitoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 631 Pages: 146-151
- DOI
  10.1016/j.bbrc.2022.09.079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06574, KAKENHI-PROJECT-21K06594, KAKENHI-PROJECT-22K06647, KAKENHI-PROJECT-20H03429, KAKENHI-PROJECT-19K07121
[Journal Article] Neuronal differentiation reporter mice as a new methodology for detecting in vivo developmental neurotoxicity2022
- Author(s)
  Ishida Keishi、Tatsumi Kanoko、Minamigawa Yoshiki、Mori Kazuma、Matsumaru Daisuke、Nagase Hisamitsu、Kanda Yasunari、Takuma Kazuhiro、Nakanishi Tsuyoshi
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 206 Pages: 115332-115332
- DOI
  10.1016/j.bcp.2022.115332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-21K06594
[Journal Article] バルプロ酸の胎内曝露による発達障害モデルの作製と新規薬物療法の追究2021
- Author(s)
  田熊一敞
- Journal Title
  
  The Journal of Child & Brain Development
  
  Volume: 12 Issue: 1 Pages: 26-33
- DOI
  10.34572/jcbd.12.1_26
- NAID
  130008104072
- ISSN
  2185-1417, 2435-8819
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-21K06594
[Journal Article] Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with familial schizophrenia2021
- Author(s)
  Yamamoto Kana、Kuriu Toshihiko、Takuma Kazuhiro、Ono Fumihito、Matsumoto Naomichi、Hashimoto Ryota、Hashimoto Hitoshi、Nakazawa Takanobu
- Journal Title
  
  Translational Psychiatry
  
  Volume: 11 Issue: 1 Pages: 548-548
- DOI
  10.1038/s41398-021-01676-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21464, KAKENHI-PROJECT-20H03556, KAKENHI-PROJECT-19H05467, KAKENHI-PLANNED-18H05416, KAKENHI-PUBLICLY-20H04774, KAKENHI-PUBLICLY-21H00213, KAKENHI-PROJECT-18H03944, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-21H02628, KAKENHI-PROJECT-21J15163, KAKENHI-PROJECT-20K07057, KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-20K07945, KAKENHI-PROJECT-21K06594, KAKENHI-PROJECT-20K21265, KAKENHI-PROJECT-21K19335, KAKENHI-PROJECT-19H01047
[Journal Article] mS-11, a mimetic of the mSin3-binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid-induced autism mouse model.2019
- Author(s)
  Kawase H, Ago Y, Naito M, Higuchi M, Hara Y, Hasebe S, Tsukada S, Kasai A, Nakazawa T, Mishina T, Kouji H, Takuma K, Hashimoto H.
- Journal Title
  
  Pharmacol Biochem Behav.
  
  Volume: 176 Pages: 1-5
- DOI
  10.1016/j.pbb.2018.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-18H05416, KAKENHI-PROJECT-17H03989, KAKENHI-PROJECT-18H02574
[Journal Article] Psychopharmacology of combined activation of the serotonin1A and σ1 receptors2017
- Author(s)
  Ago Y, Hasebe S, Hiramatsu N, Hashimoto H, Takuma K, Matsuda T
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 809 Pages: 172-177
- DOI
  10.1016/j.ejphar.2017.05.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126
[Journal Article] Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice2017
- Author(s)
  Hara Y, Ago Y, Taruta A, Hasebe S, Kawase H, Tanabe W, Tsukada S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Psychopharmacology (Berl)
  
  Volume: 234(21) Issue: 21 Pages: 3217-3228
- DOI
  10.1007/s00213-017-4703-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Anti-anhedonic effect of selective serotonin reuptake inhibitors with affinity for sigma-1 receptors in picrotoxin-treated mice2017
- Author(s)
  Hasebe S, Ago Y, Watabe Y, Oka S, Hiramatsu N, Tanaka T, Umehara C, Hashimoto H, Takuma K, Matsuda T
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 174 Issue: 4 Pages: 314-327
- DOI
  10.1111/bph.13692
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J06155, KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-16K19183, KAKENHI-PROJECT-26293020
[Journal Article] Oxytocin attenuates deficits in social interaction but not recognition memory in a prenatal valproic acid-induced mouse model of autism2017
- Author(s)
  Hara Y, Ago Y, Higuchi M, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Hormones and Behavior
  
  Volume: 96 Pages: 130-136
- DOI
  10.1016/j.yhbeh.2017.09.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Prenatal exposure to valproic acid increases miR-132 levels in the mouse embryonic brain.2017
- Author(s)
  Hara Y, Ago Y, Takano E, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K.
- Journal Title
  
  Molecular Autism
  
  Volume: 8 Issue: 1 Pages: 33-33
- DOI
  10.1186/s13229-017-0149-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Environmental enrichment attenuates behavioral abnormalities in valproic acid-exposed autism model mice2017
- Author(s)
  Yamaguchi H, Hara Y, Ago Y, Takano E, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Behav. Brain Res.
  
  Volume: 333 Pages: 67-73
- DOI
  10.1016/j.bbr.2017.06.035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Role of prefrontal serotonergic and dopaminergic systems in encounter-induced hyperactivity in methamphetamine-sensitized mice2016
- Author(s)
  Tanaka T, Ago Y, Umehara C, Imoto E, Hasebe S, Hashimoto H, Takuma K, Matsuda T.
- Journal Title
  
  Int. J. Neuropsychopharmacol.
  
  Volume: 20 Pages: 410-420
- DOI
  10.1093/ijnp/pyw115
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-14J06155, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-16K19183, KAKENHI-PROJECT-16K08268
[Journal Article] Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid-induced autism2016
- Author(s)
  Hara Y, Ago Y, Taruta A, Katashiba K, Hasebe S, Takano E, Onaka Y, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Autism Research
  
  Volume: - Issue: 9 Pages: 926-939
- DOI
  10.1002/aur.1596
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-13J05359, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-15K18874, KAKENHI-PROJECT-16K19183
[Journal Article] Involvement of GABAA receptors in 5-HT1A and σ1 receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency2016
- Author(s)
  Ago Y, Hasebe S, Hiramatsu N, Mori K, Watabe Y, Onaka Y, Hashimoto H, Takuma K, Matsuda T.
- Journal Title
  
  Psychopharmacology(Berl)
  
  Volume: 233(17) Issue: 17 Pages: 3125-3134
- DOI
  10.1007/s00213-016-4353-3
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-15K18874, KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-16K19183
[Journal Article] The novel method female encounter test2016
- Author(s)
  吾郷由希夫, 長谷部　茂, 橋本　均, 田熊一敞, 松田敏夫
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 147 Issue: 4 Pages: 230-234
- DOI
  10.1254/fpj.147.230
- NAID
  130005143846
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-16K19183
[Journal Article] Anxiolytic-like effects of restraint during the dark cycle in adolescent mice2015
- Author(s)
  Ota Y, Ago Y, Tanaka T, Hasebe S, Toratani Y, Onaka Y, Hashimoto H, Takuma K, Matsuda T
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 284 Pages: 103-111
- DOI
  10.1016/j.bbr.2015.02.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-14J06155
[Journal Article] The female encounter test, a novel method for evaluating reward-seeking behavior or motivation in mice2015
- Author(s)
  Ago Y, Hasebe S, Nishiyama S, Oka S, Onaka Y, Hashimoto H, Takuma K, Matsuda T.
- Journal Title
  
  Neuropsychopharmacol.
  
  Volume: 18(11) Issue: 11 Pages: pyv062-pyv062
- DOI
  10.1093/ijnp/pyv062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670122, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-26293020
[Journal Article] Pharmacological profile of encounter-induced hyperactivity in isolation-reared mice2015
- Author(s)
  Hasebe S, Ago Y, Nishiyama S, Oka S, Hashimoto H, Takuma K, Matsuda T
- Journal Title
  
  Behavioural Pharmacology
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099
[Journal Article] Reduced prefrontal dopaminergic activity in valproic acid-treated mouse autism model2015
- Author(s)
  Hara Y, Takuma K, Takano E, Katashiba K, Taruta A, Higashino K, Hashimoto H, Ago Y, Matsuda T.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 289 Pages: 39-47
- DOI
  10.1016/j.bbr.2015.04.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670122, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-13J05359
[Journal Article] Involvement of prefrontal AMPA receptors in encounter stimulation-induced hyperactivity in isolation-reared mice2014
- Author(s)
  Araki R, Ago Y, Hasebe S, Nishiyama S, Tanaka T, Oka S, Takuma K, Matsuda T
- Journal Title
  
  International Journal of Neuropsychopharmacology
  
  Volume: 17 Issue: 06 Pages: 883-893
- DOI
  10.1017/s1461145713001582
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-14J06155
[Journal Article] Social crowding in the night-time reduces an anxiety-like behavior and increases social interaction in adolescent mice2014
- Author(s)
  Ago Y, Tanaka T, Ota Y, Kitamoto M, Imoto E, Takuma K, Matsuda T
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 270 Pages: 37-46
- DOI
  10.1016/j.bbr.2014.04.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-14J06155
[Journal Article] Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells2013
- Author(s)
  Ota Y, Kawanai T, Watanabe R, Nishimura A, Ago Y, Takuma K, Matsuda T
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 121 Pages: 351-354
- NAID
  10031171147
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] グリア細胞Na+/Ca2+交換系の病態生理学的役割2013
- Author(s)
  田熊一敞, 吾郷由希夫, 松田敏夫
- Journal Title
  
  生体の科学(医学書院)
  
  Volume: 64(5) Pages: 384-385
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] he glial sodium-calcium exchanger: a new target for nitric oxide-mediated cellular toxicity2013
- Author(s)
  Takuma K, Ago Y, Matsuda T.
- Journal Title
  
  Curr Protein Pept Sci
  
  Volume: 14 Pages: 43-50
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells2013
- Author(s)
  Ota Y, Kawanai T, Watanabe R, Nishimura A, Ago Y, Takuma K, Matsuda T
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 121(4) Pages: 351-354
- NAID
  10031171147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] The glial sodium-calcium exchanger: a new target for nitric oxide-mediated cellular toxicity2013
- Author(s)
  Takuma K, Ago Y, Matsuda T
- Journal Title
  
  Curr Protein Pept Sci
  
  Volume: 14 Pages: 43-50
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells2013
- Author(s)
  Ota Y, Kawanai T, Watanabe R, Nishimura A, Ago Y, Takuma K, Matsuda T.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 121 Pages: 351-354
- NAID
  10031171147
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] The glial sodium-calcium exchanger : a new target for nitric oxide-mediated cellular toxicity2013
- Author(s)
  Takuma K, Ago Y, Matsuda T
- Journal Title
  
  Curr Protein Pept Sci
  
  Volume: 14 Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] Role of social encounter-induced activation of prefrontal serotonergic systems in the abnormal behaviors of isolation-reared mice2013
- Author(s)
  Yukio Ago, Ryota Araki, Tatsunori Tanaka, Asuka Sasaga, Saki Nishiyama, Kazuhiro Takuma, Toshio Matsuda
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: Vol. 38 Issue: 8 Pages: 1535-1547
- DOI
  10.1038/npp.2013.52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460099
[Journal Article] グリア細胞Na+/Ca2+交換系の病態生理学的役割2013
- Author(s)
  田熊一敞，吾郷由希夫，松田敏夫
- Journal Title
  
  生体の科学
  
  Volume: 64 Pages: 384-385
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] Neuronal nitric oxide synthase inhibition attenuates the development of L-DOPA-induced dyskinesia in hemi-Parkinsonian rats2012
- Author(s)
  Takuma K, Tanaka T, Takahashi T, Hiramatsu N, Ota Y, Ago Y, Matsuda T
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 683(1-3) Pages: 166-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] SEA0400, a specific Na+/Ca2+ exchange inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease2011
- Author(s)
  Ago Y, Kawasaki T, Nashida T, Ota Y, Cong Y, Kitamoto M, Takahashi T, Takuma K, Matsuda T
- Journal Title
  
  Neuropharmacology
  
  Volume: 61(8) Pages: 1441-1451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] Nicotine ameliorates impairment of working memory in methamphetamine-treated rats2011
- Author(s)
  Hiroyuki Mizoguchi, Daisuke Ibi, Fumiaki Takase, Taku Nagai, Hiroyuki Kamei, Erika Toth, Jun Sato, Kazuhiro Takuma, Kiyofumi Yamada
- Journal Title
  
  Behav.Brain Res. 220(1)
  
  Pages: 159-163
- Data Source
  KAKENHI-PROJECT-20590083
[Journal Article] Aβトランスポーター2010
- Author(s)
  田熊一敞片岡駿介, 吾郷由希夫, 松田敏夫
- Journal Title
  
  脳21 13
  
  Pages: 59-62
- Data Source
  KAKENHI-PROJECT-20590083
[Journal Article] Aβトランスポーター2010
- Author(s)
  田熊, 一敞(一浩)
- Journal Title
  
  脳21 13
  
  Pages: 59-62
- Data Source
  KAKENHI-PROJECT-20590083
[Journal Article] Alterations of emotional and cognitive behaviors in matrix metalloproteinase-2 and -9-deficient mice2010
- Author(s)
  Hiroyuki Mizoguchi, Daisuke Ibi, Kazuhiro Takuma, Erika Toth, Jun Sato, Shigeyoshi Itohara, Toshitaka Nabeshima, Kiyofumi Yamada
- Journal Title
  
  Open Behav.Sci.J. 4
  
  Pages: 19-25
- Data Source
  KAKENHI-PROJECT-20590083
[Journal Article] ミトコンドリア障害と神経系のアポトーシス～アルツハイマー病解明へのアプローチ～2009
- Author(s)
  田熊一敞, 片岡駿介, 吾郷由希夫, 松田敏夫
- Journal Title
  
  日本薬理学雑誌 134(4)
  
  Pages: 180-183
- NAID
  10025741619
- Data Source
  KAKENHI-PROJECT-20590083
[Journal Article] ミトコンドリア障害と神経系のアポトーシス～アルツハイマー病解明へのアプローチ～2009
- Author(s)
  田熊, 一敞(一浩)
- Journal Title
  
  日本薬理学雑誌 134
  
  Pages: 180-183
- NAID
  10025741619
- Data Source
  KAKENHI-PROJECT-20590083
[Journal Article] Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood.2009
- Author(s)
  Ibi D, Nagai T, Kitahara Y, Mizoguchi H, Koike H, Shiraki A, Takuma K, Kamei H, Noda N, Nitta A, Nabeshima T, Yoneda Y, Yamada K
- Journal Title
  
  Neurosci.Res. 64
  
  Pages: 297-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Matrix metalloprotease-9 inhibition improves amyloid β-mediated cognitive impairment and neurotoxicity in mice2009
- Author(s)
  Hiroyuki Mizoguchi, Kazuhiro Takuma, Emiko Fukuzaki, Daisuke Ibi, Eiichi Someya, Ko-hei Akazawa, Tursun Alkam, Hiroko Tsunekawa, Akihiro Mouri, Yukihiro Noda, Toshitaka Nabeshima, Kiyofumi Yamada
- Journal Title
  
  J.Pharmacol.Exp.Ther. 331(1)
  
  Pages: 14-22
- Data Source
  KAKENHI-PROJECT-20590083
[Journal Article] RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction2009
- Author(s)
  TAKUMA, Kazuhiro
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106
  
  Pages: 20021-20026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590083
[Journal Article] RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction2009
- Author(s)
  Takuma K, et al.
- Journal Title
  
  Proc Natl Acad Sci USA 106(47)
  
  Pages: 20021-20026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Matrix metalloprotease-9 inhibition improves amyloid β-mediated cognitive impairment and neurotoxicity in mice2009
- Author(s)
  Mizoguchi H, Takuma K, Fukuzaki E, Ibi D, Someya E, Akazawa K, Alkam T, Tsunekawa H, Mouri A, Noda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Pharmacol.Exp.Ther. 331
  
  Pages: 14-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction2009
- Author(s)
  Kazuhiro Takuma, Fang Fang, Wensheng Zhang, Shiqiang Yan, Emiko Fukuzaki, Heng Du, Alexander Sosunov, Guy McKhann, Yoko Funatsu, Noritaka Nakamichi, Taku Nagai, Hiroyuki Mizoguchi, Daisuke Ibi, Osamu Hori, Satoshi Ogawa, David M.Stern, Kiyofumi Yamada, Shirley ShiDu Yan
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106(47)
  
  Pages: 20021-20026
- Data Source
  KAKENHI-PROJECT-20590083
[Journal Article] Matrix metalloprotease-9 inhibition improves amyloid.-mediated cognitive impairment and neurotoxicity in mice.2009
- Author(s)
  Mizoguchi H, Takuma K, Fukuzaki E, Ibi D, Someya E, Akazawa K, Alkam T, Tsunekawa H, Mouri A, Noda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Pharmacol.Exp.Ther. 331
  
  Pages: 14-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Therapeutic potential of nicotine for methamphetamine-induced impairment of sensorimotor gating : involvement of pallidotegmental neurons.2009
- Author(s)
  Mizoguchi H, Arai S, Koike H, Ibi D, Kamei H, Nabeshima T, Kim HC, Takuma K, Yamada K
- Journal Title
  
  Psychopharmacology 207
  
  Pages: 235-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Tissue plasminogen activator is not involved in methamphetamine-induced neurotoxicity.2008
- Author(s)
  Fukakusa A, Mizoguchi H, Koike H, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Pharmacol.Sci. 106
  
  Pages: 321-324
- NAID
  10024318646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Ovariectomy increases serum amyloid β peptide and hippocampal ABAD levels in mice2008
- Author(s)
  Emiko Fukuzaki, Kazuhiro Takuma, Yoko Funatsu, Yukiko Himeno, Yuko Kitahara, Hiroyuki Mizoguchi, Daisuke Ibi, Koji Koike, Masaki Inoue, Shi Du Yan, Kiyofumi Yamada
- Journal Title
  
  Nuerochem.Int. 52(7)
  
  Pages: 1358-1364
- Data Source
  KAKENHI-PROJECT-20590083
[Journal Article] Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice2008
- Author(s)
  Ibi D, Takuma K, Koike H, Mizoguchi H, Tsuritani K, Kuwahara Y, Kamei H, Nagai T, Yoneda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Neurochem 105
  
  Pages: 921-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens2008
- Author(s)
  Fukakusa A, Nagai T, Mizoguchi H, Otsuka N, Kimura H, Kamei H, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem 105
  
  Pages: 436-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens.2008
- Author(s)
  Fukakusa A, Nagai T, Mizoguchi H, Otsuka N, Kimura H, Kamei H, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem. 105
  
  Pages: 436-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice.2008
- Author(s)
  Ibi D, Takuma K, Koike H, Mizoguchi H, Tsuritani K, Kuwahara Y, Kamei H, Nagai T, Yoneda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Neurochem. 105
  
  Pages: 921-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Ginkgo biloba extract EGb761 attenuates hippocampal neuronal loss and cognitive dysfunction resulting from chronic restraint stress in ovariectomized rats.2007
- Author(s)
  Takuma K, Hoshina, Y, Arai S, Himeno Y, Matsuo, A, Funatsu Y, Kitahara Y, Ibi, D, Hayase M, Kamei H, Mizoguchi H, Nagai T, Koike K, Inoue M, Yamada K
- Journal Title
  
  Neuroscience 149
  
  Pages: 256-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] 17β-Estradiol attenuates hippocampal neuronal loss and cognitive dysfunction induced by chronic restraint stress in ovariectomized rats.2007
- Author(s)
  TAKUMA, Kazuhiro
- Journal Title
  
  Neuroscience (in press)
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] 17β-Estradiol attenuates hippocampal neuronal loss and cognitive dysfunction induced by chronic restraint stress in ovariectomized rats2007
- Author(s)
  TAKUMA, Kazuhiro
- Journal Title
  
  Neuroscience 146
  
  Pages: 60-68
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] Ginkgo biloba extract EGb 761 attenuates hippocampal neuronal loss and cognitive dysfunction resulting from chronic restraint stress in ovariectomized rats2007
- Author(s)
  TAKUMA, Kazuhiro
- Journal Title
  
  Neuroscience 149
  
  Pages: 256-262
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] Activation of post-synaptic dopamine D1 receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling.2007
- Author(s)
  Ito M, Nagai T, Mizoguchi H, Sato K, Hayase M, Otsuka N, Fukakusa A, Kumagai N, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem. 103
  
  Pages: 2589-2596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Ginkgo biloba extract EGb 761 attenuates hippocampal neuronal loss and cognitive dysfunction resulting from chronic restraint stress in ovariectomized rats2007
- Author(s)
  Kazuhiro, Takuma
- Journal Title
  
  Neuroscience 149-2
  
  Pages: 256-262
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] 17β-Estradiol attenuates hippocampal neuronal loss and cognitive dysfunction induced by chronic restraint stress in ovariectomized rats2007
- Author(s)
  Kazuhiro, Takuma
- Journal Title
  
  Neuroscience 146-1
  
  Pages: 60-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] Activation of post-synaptic dopamine D_1 receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling2007
- Author(s)
  Ito M, Nagai T, Mizoguchi H, Sato K, Hayase M, Otsuka N, Fukakusa A, Kumagai N, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem 103
  
  Pages: 2589-2596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Ginkgo blioba extract EGb761 attenuates hippocampal neuronal loss and cognitivedysfunction resultine from chronic restraint stress in ovariectomized rats.2007
- Author(s)
  Takuma K, et. al.
- Journal Title
  
  Neuroscience 149
  
  Pages: 256-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] 中枢神経系のアポトーシスにおけるミトコンドリアの役割に関する研究2006
- Author(s)
  田熊, 一敞
- Journal Title
  
  日本薬理学雑誌 127
  
  Pages: 349-354
- NAID
  10018061567
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] 中枢神経系のアポトーシスにおけるミトコンドリアの役割に関する研究2006
- Author(s)
  田熊, 一敞
- Journal Title
  
  神経化学 45
  
  Pages: 669-680
- NAID
  10018061567
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] 中枢神経系のアポトーシスにおけるミトコンドリアの役割に関する研究2006
- Author(s)
  田熊, 一敞
- Journal Title
  
  日本薬理学雑誌 127・5
  
  Pages: 349-354
- NAID
  10018061567
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] Molecular mechanism of delayed apoptosis in astrocytes2006
- Author(s)
  Kazuhiro, Takuma
- Journal Title
  
  Shinkei Kagaku 45-4
  
  Pages: 669-680
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] 中枢神経系のアポトーシスにおけるミトコンドリアの役割に関する研究2006
- Author(s)
  田熊, 一敞
- Journal Title
  
  日本薬理学雑誌 127(5)(in press)
- NAID
  10018061567
- Data Source
  KAKENHI-PROJECT-15790140
[Journal Article] 中枢神経系のアポトーシスにおけるミトコンドリアの役割に関する研究2006
- Author(s)
  田熊, 一敞
- Journal Title
  
  神経化学 45・4
  
  Pages: 669-680
- NAID
  10018061567
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] Mitochondrial, dysfunction, and apoptosis in neurodegenerative diseases2006
- Author(s)
  Kazuhiro, Takuma
- Journal Title
  
  Nippon Yakurigaku Zasshi 147-5
  
  Pages: 349-354
- NAID
  10018061567
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Journal Article] Mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis in Alzheimer's disease2005
- Author(s)
  TAKUMA, Kazuhiro
- Journal Title
  
  Journal of Pharmacological Sciences 97(3)
  
  Pages: 312-316
- NAID
  10025726364
- Data Source
  KAKENHI-PROJECT-15790140
[Journal Article] ABAD enhances Aβ-induced cell stress via mitochondrial dysfunction2005
- Author(s)
  TAKUMA, Kazuhiro
- Journal Title
  
  The FASEB Journal 19(4)
  
  Pages: 597-598
- Data Source
  KAKENHI-PROJECT-15790140
[Journal Article] Mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis in Alzheimer's disease2005
- Author(s)
  TAKUMA, Kazuhiro
- Journal Title
  
  Journal of Pharmacological Sciences 97(3)(in press)
- NAID
  10025726364
- Data Source
  KAKENHI-PROJECT-15790140
[Journal Article] グリア細胞の遅発性アポトーシス2005
- Author(s)
  田熊, 一敞
- Journal Title
  
  Clinical Neuroscience 23(2)
  
  Pages: 181-183
- Data Source
  KAKENHI-PROJECT-15790140
[Journal Article] ABAD enhances Aβ-induced cell stress via mitochondrial dysfunction2005
- Author(s)
  TAKUMA, Kazuhiro
- Journal Title
  
  The FASEB Journal 19(4)(in press)
- Data Source
  KAKENHI-PROJECT-15790140
[Journal Article] Astorocyte apoptosis: implications for neuroprotection2004
- Author(s)
  TAKUMA, Kazuhiro
- Journal Title
  
  Progress in Neurobiology 72(2)
  
  Pages: 111-127
- Data Source
  KAKENHI-PROJECT-15790140
[Journal Article] 脳とプロテアーゼ2004
- Author(s)
  田熊, 一敞
- Journal Title
  
  脳21 7(2)
  
  Pages: 189-194
- Data Source
  KAKENHI-PROJECT-15790140
[Presentation] ヒト染色体3q29領域欠失を導入した自閉スペクトラム症モデルマウスの社会行動異常はオキシトシンの投与により回復する2023
- Author(s)
  竹本智哉, 馬場優志, 北川航平, 永安一樹, 勢力薫, 早田敦子, 笠井淳司, 吾郷由希夫, 田熊一敞, 橋本亮太, 橋本均, 中澤敬信
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06594
[Presentation] 誕生日タグづけ法を用いた胎仔期バルプロ酸暴露による大脳皮質細胞分布異常の全脳解析2023
- Author(s)
  瀬尾慧, 笠井淳司, 植野寛貴, 中井悠花, 島崎雄人, 田沼将人, 馬場優志, 吉永怜史, 大久保仁, 勢力薫, 田熊一敞, 久保健一郎, 橋本均
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06594
[Presentation] 発達期大脳皮質体性感覚野ニューロンにおいて間歇的低酸素負荷がシナプス活動に与える影響2023
- Author(s)
  豊田博紀，早田敦子，片桐綾乃，山田雅治，田熊一敞，加藤隆史
- Organizer
  第100回　日本生理学会
- Data Source
  KAKENHI-PROJECT-21K19594
[Presentation] Intranasal oxytocin administration suppresses social contact-induced neural activity in a POGZ-Q1038R mutant mouse model of autism spectrum disorder2022
- Author(s)
  Kitagawa K, Baba M, Takemoto T, Tanuma M, Hayashida M, Yamaguchi S, Ago Y, Seiriki K, Hayata-Takano A, Takuma K, Kasai A, Hashimoto H, Nakazawa T
- Organizer
  Neuroscience 2022 (The 51st Annual Meeting of the Society for Neuroscience)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06594
[Presentation] 鎮痛作用を示さない低用量μオピオイド受容体アゴニストは自閉スペクトラム症モデルマウスの社会性行動障害を改善する2022
- Author(s)
  吾郷由希夫, 内藤恵, 川瀬啓生, 樋口桃子, 山川英訓, 大波壮一郎, 小川公一, 中邨篤史, 河内貴弘, 今戸瑛二, 田原孟, 浅野智志, 古武弥一郎, 田熊一敞, 橋本均
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-21K06594
[Presentation] 間歇的低酸素負荷が発達期の大脳皮質体性感覚野ニューロンの神経活動に及ぼす影響2022
- Author(s)
  豊田博紀，早田敦子，片桐綾乃，山田雅治，田熊一敞，加藤隆史
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K19594
[Presentation] マウス胎生期のバルプロ酸曝露は脊髄でのミクログリアの増殖とアロディニアを引き起こす2022
- Author(s)
  吾郷由希夫, 今戸瑛二, Samnang Sun, 中村庸輝, 中島一恵, 森岡徳光, 田熊一敞, 木口倫一, 浅野智志
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-21K06594
[Presentation] ASDモデルマウスの社会性行動と前頭前皮質の機能異常2022
- Author(s)
  笠井淳司, 彌永祐輔, 植野寛貴, 中井悠花, 原雄大, 三浦大樹, 田沼将人, 林田美鈴, 横山玲, 大久保仁, 勢力薫, 早田敦子, 山口瞬, 北岡志保, 古屋敷智之, 吾郷由希夫, 中澤敬信, 田熊一敞, 橋本均
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06594
[Presentation] TRPV1アンタゴニストAMG517は胎生期バルプロ酸投与誘発の自閉症モデルマウスにおいて痛覚感受性の異常と社会性行動障害を改善する2022
- Author(s)
  田原孟, 今戸瑛二, 川瀬啓生, 樋口桃子, 山川英訓, 小川公一, 古武弥一郎, 田熊一敞, 橋本均, 浅野智志, 吾郷由希夫
- Organizer
  第96回日本薬理学会年会 (JPW2022)
- Data Source
  KAKENHI-PROJECT-21K06594
[Presentation] 神経発達障害モデルマウスにおける機械的アロディニアの発症とミクログリアの関与2022
- Author(s)
  今戸瑛二, Samnang Sun, Abawa Abrar, 浅野智志, 中村庸輝, 中島一恵, 森岡徳光, 津賀一弘, 入舩正浩, 田熊一敞, 木口倫一, 吾郷由希夫
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06594
[Presentation] 胎生期バルプロ酸投与マウスは熱刺激およびカプサイシン誘発痛の増大と機械的アロディニアを示す2021
- Author(s)
  今戸瑛二, 浅野智志, 中村庸輝, 中島一恵, 森岡徳光, 津賀一弘, 入舩正浩, 田熊一敞, 吾郷由希夫
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06594
[Presentation] ヒト染色体3q29領域欠失を導入した自閉スペクトラム症モデルマウスの社会性行動異常はオキシトシンの投与により回復する2021
- Author(s)
  竹本智哉, 馬場優志, 北川航平, 永安一樹, 勢力薫, 早田敦子, 笠井淳司, 吾郷由希夫, 田熊一敞, 橋本均, 中澤敬信
- Organizer
  第140回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06594
[Presentation] Effects of intranasal oxytocin on autism-like behavioral abnormalities in valproic acid-induced mouse model of autism2018
- Author(s)
  Yuta Hara, Yukio Ago, Momoko Higuchi, Shigeru Hasebe, Takanobu Nakazawa, Hitoshi Hashimoto, Toshio Matsuda, Kazuhiro Takuma
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] Selective serotonin reuptake inhibitors with affinity for σ1 receptors exert anti-anhedonic effect in picrotoxin-induced model of anxiety/depression2017
- Author(s)
  吾郷由希夫, 長谷部茂, 樋口桃子, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] メタンフェタミン退薬時の社会的刺激による多動反応と前頭前野セロトニン、ドパミン神経系の活性化2017
- Author(s)
  梅原千晶, 吾郷由希夫, 田中辰典, 長谷部茂, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎パブリックホール
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] 自閉症モデルマウスにおける前頭前皮質ドパミン神経系の異常～ADHD治療薬による行動異常の改善2016
- Author(s)
  吾郷由希夫, 原雄大, 前田優子, 長谷部茂, 橋本均, 松田敏夫, 田熊一敞
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  ソウル市, 韓国
- Year and Date
  2016-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] ドパミン神経賦活薬の慢性投与は胎仔期バルプロ酸曝露マウスの自閉症様行動を改善する2016
- Author(s)
  長谷部茂, 原雄大, 樋口桃子, 吾郷由希夫, 中澤敬信, 橋本均, 松田敏夫, 田熊一敞
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡国際会議場 (福岡県福岡市)
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] Continuous activation of dopaminergic system improves autism-related behavioral abnormalities in mice prenatally exposed to valproic acid2016
- Author(s)
  Hasebe S, Hara Y, Higuchi M, Ago Y, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Organizer
  The 46th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] 雌性マウスを用いた意欲・報酬探索行動評価試験2016
- Author(s)
  川瀬啓生, 吾郷由希夫, 長谷部茂, 岡智史, 田熊一敞, 松田敏夫, 橋本均
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] マウスエンカウンター試験を用いた覚せい剤精神病のストレス再燃の解析2016
- Author(s)
  田中辰典, 吾郷由希夫, 梅原千晶, 尾中勇祐, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 雌性マウスを用いた意欲・報酬探索行動評価試験2016
- Author(s)
  川瀬啓生, 吾郷由希夫, 長谷部茂, 岡智史, 田熊一敞, 松田敏夫, 橋本均
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館 (広島県広島市)
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] 精神的ストレスによる覚せい剤精神病の再燃現象におけるセロトニン受容体の関与2016
- Author(s)
  田中辰典, 吾郷由希夫, 梅原千晶, 長谷部茂, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  第13回GPCR研究会
- Place of Presentation
  日本科学未来館
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] メタンフェタミン反復投与マウスの精神的ストレスによる多動反応の神経化学的基盤2015
- Author(s)
  田中辰典, 吾郷由希夫, 梅原千晶, 尾中勇祐, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  第128回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 雌選択性試験：マウス間相互作用を基盤とした新規うつ様行動評価系2015
- Author(s)
  長谷部茂, 岡智史, 尾中勇祐, 橋本均, 松田敏夫, 吾郷由希夫, 田熊一敞
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] Development of a novel method for assessing motivation in male mice2015
- Author(s)
  Hasebe S, Ago Y, Oka S, Onaka Y, Hashimoto H, Matsuda T, Takuma K
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  大宮ソニックシティ
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] エンカウンター刺激を利用した新規マウス意欲評価試験の開発2015
- Author(s)
  長谷部茂, 吾郷由希夫, 岡智史, 渡部雄二, 尾中勇祐, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  第128回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 雌雄エンカウンター刺激を用いた新規マウス意欲評価系2015
- Author(s)
  長谷部茂, 吾郷由希夫, 岡智史, 尾中勇祐, 橋本均, 松田敏夫, 田熊一敞
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] マウス活動期における拘束ストレスは抗不安様作用を示す2015
- Author(s)
  田中辰典, 太田友樹, 大住康晃, 長谷部茂, 尾中勇祐, 橋本均, 松田敏夫, 田熊一敞, 吾郷由希夫
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 抗うつ薬による長期隔離飼育マウスのエンカウンター誘発多動反応抑制の作用機序2014
- Author(s)
  岡智史, 長谷部茂, 西山早紀, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第64回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 長期隔離飼育マウスのうつ病モデルマウスとしての薬理学的有用性2014
- Author(s)
  西山早紀, 長谷部茂, 吾郷由希夫, 岡　智史, 田熊一敞, 松田敏夫
- Organizer
  第64回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 精神刺激薬反復投与マウスのマウス間相互作用の異常2014
- Author(s)
  田中辰典, 吾郷由希夫, 井本絵実奈, 田熊一敞, 松田敏夫
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 隔離飼育マウスのエンカウンター誘発多動に対する抗うつ薬の多動抑制メカニズム2014
- Author(s)
  長谷部茂, 西山早紀, 岡智史, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 長期隔離飼育マウスのエンカウンター刺激による多動発現におけるAMPA受容体の関与2014
- Author(s)
  荒木良太, 吾郷由希夫, 矢部武士, 田熊一敞, 松田敏夫
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2014
- Place of Presentation
  近畿大学（東大阪）
- Year and Date
  2014-08-30
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 過密飼育環境の夜間負荷による発育期マウス精神機能の変化2014
- Author(s)
  田中辰典, 吾郷由希夫, 井本絵実奈, 北本真理, 太田友樹, 田熊一敞, 松田敏夫
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] 長期隔離飼育マウスのエンカウンター誘発多動反応の薬理学的プロファイル2014
- Author(s)
  長谷部茂, 吾郷由希夫, 西山早紀, 岡智史, 中森大貴, 田熊一敞, 松田敏夫
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] Neurochemical and behavioral responses of psychiatric disorder model mice to social encounter2013
- Author(s)
  Kazuhiro Takuma, Shigeru Hasebe, Tatsunori Tanaka, Saki Nishiyama, Yuko Maeda, Ryota Araki, Yukio Ago, Toshio Matsuda
- Organizer
  The 43rd annual meeting of the Society for Neuroscience (Neuroscience 2013)
- Place of Presentation
  San Diego Convention Center （San Diego, USA）
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 精神疾患モデルマウスにおけるエンカウター刺激による前頭葉モノアミン神経変化と行動異常発現へのAMPA受容体の関与2013
- Author(s)
  西山早紀、荒木良太、吾郷由希夫、田中辰典、田熊一敞、松田敏夫
- Organizer
  第63回日本薬学会近畿支部総会・大会
- Place of Presentation
  同志社女子大学(京都)
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] PACAP 遺伝子欠損マウスの異常行動に対する自発運動の作用2013
- Author(s)
  中川光, 福山留以, 山口浩史, 新谷紀人, 橋本均, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] 精神疾患モデルへのエンカウンター刺激による長期隔離マウス行動異常発現におけるAMPA受容体の役割2013
- Author(s)
  西山早紀、荒木良太、吾郷由希夫、田中辰典、長谷部茂、田熊一敞、松田敏夫
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都ガーデンパレス(京都)
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 精神障害モデルマウスにおける個体間相互作用応答性の異常2013
- Author(s)
  田中辰典、長谷部茂、吾郷由希夫、荒木良太、西山早紀、井本絵実奈、田熊一敞、松田敏夫
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  沖縄コンベンションセンター(沖縄)
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] レボドパ誘発ジスキネジア形成過程における神経型一酸化窒素合成酵素の役割2012
- Author(s)
  田熊一敞, 田中辰典, 高橋剛士, 太田友樹, 平松直樹, 吾郷由希夫, 松田敏夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] 発育期環境要因のマウス精神機能発達に対する作用2012
- Author(s)
  田中辰典, 吾郷由希夫, 井本絵実奈, 北本真理, 田熊一敞, 松田敏夫
- Organizer
  第62回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] PACAP 欠損マウスの学習記憶障害に対する豊かな環境飼育の影響2012
- Author(s)
  福山留以, 竹本光佑, 中川光, 新谷紀人, 橋本均, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第121回日本薬理学会近畿部会
- Place of Presentation
  徳島
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] 幼若期環境強化によるPACAP 遺伝子欠損マウス学習記憶障害の発現抑制2012
- Author(s)
  中川光, 竹本光佑, 福山留以, 新谷紀人, 橋本均, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  生体機能と創薬シンポジウム2012
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] 6-Hydroxydopamine 神経障害ラットにおけるL-DOPA 誘発ジスキネジアの形成に対する神経型一酸化窒素合成酵素阻害薬7-nitroindazole の改善効果2012
- Author(s)
  太田友樹, 田熊一敞, 高橋剛士, 吾郷由希夫, 松田敏夫
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] Receptor for advanced glycation endproducts : a potential target for amyloid-β peptide-mediated neuropathology.2011
- Author(s)
  Kazuhiro Takuma
- Organizer
  第84回日本薬理学会年会シンポジウム
- Place of Presentation
  大会中止のため誌上開催(招待講演)
- Year and Date
  2011-02-15
- Data Source
  KAKENHI-PROJECT-20590083
[Presentation] 糖化最終産物受容体を介するアミロイド神経毒性発現とその薬物標的としての可能性2011
- Author(s)
  田熊一敞, 松田敏夫, 山田清文
- Organizer
  第84回日本薬理学会年会シンポジウム
- Place of Presentation
  大会中止のため誌上開催
- Year and Date
  2011-02-15
- Data Source
  KAKENHI-PROJECT-20590083
[Presentation] 選択的Na+/Ca2+交換系阻害はMPTP誘発パーキンソン病マウスモデルの黒質・線条体ドパミン障害を軽減する2011
- Author(s)
  田熊一敞, ら
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川(招待講演)
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] 神経型一酸化窒素合成酵素阻害剤7-nitroindazole は6-hydroxydopamine 神経障害ラットにおいてL-DOPA 誘発ジスキネジアの形成を抑制する2011
- Author(s)
  太田友樹, 田熊一敞, 高橋剛士, 吾郷由希夫, 松田敏夫
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] Mitochondria-mediated neurotoxicity in Alzheimer's disease.2010
- Author(s)
  田熊一敞, 松田敏夫
- Organizer
  第37回日本トキシコロジー学会学術年会シンポジウム
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20590083
[Presentation] Mitochondria-mediated neurotoxicity in Alzheimer's disease.2010
- Author(s)
  Kazuhiro Takuma
- Organizer
  第37回日本トキシコロジー学会学術年会シンポジウム
- Place of Presentation
  沖縄県沖縄コンベンションセンター(招待講演)
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20590083
[Presentation] ミトコンドリア障害と神経系のアポトーシス～アルツハイマー病解明へのアプローチ～2009
- Author(s)
  田熊一敞, 片岡駿介, 吾郷由希夫, 松田敏夫
- Organizer
  第82回日本薬理学会年会シンポジウム
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590083
[Presentation] ミトコンドリア障害と神経系のアポトーシス〜アルツハイマー病解明へのアプローチ〜2009
- Author(s)
  田熊, 一敞(一浩)
- Organizer
  第82回日本薬理学会年会シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590083
[Presentation] Role of receptor for advanced glycation endproducts in neuronal amyloid β-peptide membrane transport2008
- Author(s)
  Kazuhiro Takuma, Emiko Fukuzaki, Yoko Funatsu, David M.Stern, 山田清文, Shi Du Yan
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease (ICAD2008)
- Place of Presentation
  McCormick Place, Chicago, IL, USA.
- Year and Date
  2008-07-30
- Data Source
  KAKENHI-PROJECT-20590083
[Presentation] マウス培養神経細胞の細胞内Aβ移行におけるRAGEの役割2008
- Author(s)
  田熊, 一敞
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18590050
[Presentation] Role of receptor for advanced glycation end products on neuronal membrane transport of amyloid β-peptide2008
- Author(s)
  Kazuhiro, Takuma
- Organizer
  The 128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Presentation] マウス培養神経細胞の細胞内Aβ移行におけるRAGEの役割2008
- Author(s)
  田熊, 一敞
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Presentation] Role of receptor for advanced glycation endproducts inneuronal amyloid β-peptide membrane transport2008
- Author(s)
  TAKUMA, Kazuhiro
- Organizer
  The Alzheimer's Association 2008 International Conference on Alzheimer's Disease (ICAD2008)
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2008-07-30
- Data Source
  KAKENHI-PROJECT-20590083
[Presentation] Alzheimer病におけるミトコンドリア機能破綻の分子機序2007
- Author(s)
  田熊, 一敞
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2007-03-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Presentation] Mitochondria] dysfunction and neuronal apoptosis in Alzheimer's disease2007
- Author(s)
  Kazuhiro, Takuma
- Organizer
  The 80th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Nagoya
- Year and Date
  2007-03-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Presentation] 覚せい剤による依存・精神病性障害と認知機能障害における組織プラスミノーゲン活性化因子の関与(シンポジウム「アルコール・薬物依存の基礎研究の動向」).2007
- Author(s)
  山田清文, 永井拓, 溝口博之, 鍋島俊隆, 田熊一敞
- Organizer
  第42回日本アルコール・薬物医学会, 第19回日本アルコール精神医学会, 第10回ニコチン・薬物依存研究フォーラム平成19年度合同学術総会.
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 脳グリア細胞遅発性アポトーシスの分子メカニズム2006
- Author(s)
  田熊, 一敞
- Organizer
  第49回日本神経化学会大会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2006-09-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Presentation] Molecular mechanism of delayed apoptosis in astrocytes2006
- Author(s)
  Kazuhiro, Takuma
- Organizer
  The 49th Annual Meeting of the Japanese Society of Neurochemistry
- Place of Presentation
  Nagoya
- Year and Date
  2006-09-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590050
[Presentation] Encounter stimulation-induced hyperactivity of social isolation-reared mice is attenuated by antidepressants
- Author(s)
  Hasebe S, Ago Y, Nishiyama S, Oka S, Nakamori D, Takuma K, Matsuda T
- Organizer
  The 44th Annual Meeting of the Society for Neuroscience (Neuroscience 2014)
- Place of Presentation
  Walter E. Washington Convention Center (Washington, D.C., USA)
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 夜間拘束ストレスの抗不安様作用
- Author(s)
  田中辰典, 太田友樹, 長谷部茂, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸（神戸）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] Rearing in overcrowded conditions in the night-time induces anxiolytic-like effects in adolescent mice
- Author(s)
  Tanaka T, Ago Y, Ota Y, Imoto E, Kitamoto M, Takuma K, Matsuda T
- Organizer
  The 44th Annual Meeting of the Society for Neuroscience (Neuroscience 2014)
- Place of Presentation
  Walter E. Washington Convention Center (Washington, D.C., USA)
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 精神刺激薬反復投与マウスのエンカウンター刺激による多動
- Author(s)
  田中辰典, 吾郷由希夫, 井本絵実奈, 田熊一敞, 松田敏夫
- Organizer
  第36回日本生物学的精神医学会・第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良県文化会館（奈良）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 夜間拘束ストレスはマウスの不安様行動を減少させる
- Author(s)
  太田友樹, 田中辰典, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第36回日本生物学的精神医学会・第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良県文化会館（奈良）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 長期隔離飼育マウスのエンカウンター異常反応の神経薬理学的解析
- Author(s)
  長谷部茂, 吾郷由希夫, 西山早紀, 岡智史, 田熊一敞, 松田敏夫
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫医療大学（神戸）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 長期隔離飼育マウスのエンカウンター誘発多動反応のADHD治療薬による抑制
- Author(s)
  長谷部茂, 西山早紀, 岡智史, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸（神戸）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] Social crowding in the night-time reduces an anxiety-like behavior and increases social interaction in adolescent mice
- Author(s)
  Ota Y, Ago Y, Tanaka T, Kitamoto M, Imoto E, Takuma K, Matsuda T
- Organizer
  The 8th Soul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists
- Place of Presentation
  大阪大学（吹田）
- Year and Date
  2014-06-10 – 2014-06-11
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 長期隔離飼育マウスのエンカウンター誘発多動反応に対する抗うつ薬の作用
- Author(s)
  長谷部茂, 吾郷由希夫, 西山早紀, 岡智史, 中森大貴, 田熊一敞, 松田敏夫
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] マウス間相互作用を基盤とした新規意欲評価系
- Author(s)
  吾郷由希夫, 長谷部茂, 西山早紀, 岡智史, 尾中勇祐, 田熊一敞, 松田敏夫
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460099

1. AGO Yukio (50403027)

# of Collaborated Projects: 5 results

# of Collaborated Products: 62 results
2. MATSUDA Toshio (00107103)

# of Collaborated Projects: 4 results

# of Collaborated Products: 56 results
3. NAGAI Taku (10377426)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
4. 松崎伸介 (60403193)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YAMADA Kiyofumi (30303639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
6. MIZOGUCHI Hiroyuki (70402568)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
7. HASHIMOTO Hitoshi (30240849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
8. MORI Koichi (20098487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 長谷部茂 (30754725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 豊澤悟 (30243249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 廣瀬勝俊 (00824898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 鵜澤成一 (30345285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 阿部真土 (40448105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 廣瀬由美子 (60528785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 宇佐美悠 (80444579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 松井崇浩 (50747037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 高村明孝 (80514398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 雑賀史浩 (10644099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 長井克仁 (00351271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 加藤隆史 (50367520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. 豊田博紀 (00432451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. 片桐綾乃 (40731899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. 永瀬久光 (40141395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 中西剛 (50303988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 松丸大輔 (50624152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 石田慶士 (90908310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. HARA Yuta

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
28. MAEDA Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. NAKAZAWA Takanobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
30. 橋本亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
31. 高崎一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 高野敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

takuma kazuhiro 田熊 一敞

TAKUMA Kazuhiro 田熊 一敞

田熊 一敞 タクマ カズヒロ

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Basic research on suppressing the pathogenesis of autism spectrum disorder by targeting oxytocin neural networkPrincipal Investigator

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Clarification of the molecular pathogenesis of autism spectrum disorders through the analysis regarding sex differencesPrincipal Investigator

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Neurochemical study for cognitive behavioral therapy in mouse models of neuropsychiatric and neurodevelopmental disordersPrincipal Investigator

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Molecular Analysis of cognitive impairment associated with postmenopausal memory loss and Alzheimer's diseasePrincipal Investigator

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Molecular mechanisms of mitochondrial dysfunction and neurotoxicity induced by Aβ-ARAD interactionPrincipal Investigator

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takuma kazuhiro 田熊一敞

TAKUMA Kazuhiro 田熊一敞

田熊一敞タクマカズヒロ