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OSAWA Haruhiko  大澤 春彦

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OOSAWA Haruhiko  大澤 春彦

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Researcher Number 90294800
Other IDs
External Links
Affiliation (Current) 2025: 愛媛大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2016 – 2024: 愛媛大学, 医学系研究科, 教授
2011 – 2016: 愛媛大学, 医学(系)研究科(研究院), 教授
2015: 愛媛大学, 大学院医学研究科, 教授
2015: 愛媛大学, 大学院医学系研究科, 教授
2013: 愛媛大学, 大学院医学系研究科, 教授 … More
2008 – 2012: Ehime University, 大学院・医学系研究科, 教授
2009: 愛媛大学, 医学部, 教授
2007 – 2008: 愛媛大学, 大学院・医学系研究科, 准教授
2006: Ehime University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授
2006: 愛媛大学, 大学院医学系研究科, 助教授
1999 – 2005: 愛媛大学, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Metabolomics / Basic Section 54040:Metabolism and endocrinology-related / Metabolomics / Biological Sciences
Except Principal Investigator
Laboratory medicine / Metabolomics / Basic Section 52010:General internal medicine-related / Metabolomics / Biological Sciences / Basic Section 58030:Hygiene and public health-related: excluding laboratory approach … More / Basic Section 52030:Psychiatry-related / Internal medicine of the bio-information integration and related fields / Epidemiology and preventive medicine / Hygiene and public health / Collagenous pathology/Allergology / Public health/Health science Less
Keywords
Principal Investigator
インスリン抵抗性 / レジスチン / 遺伝子発現 / 2型糖尿病 / SNP / 遺伝子 / 糖尿病 / 環境因子 / エピジェネティクス / 脂肪細胞 … More / diabetes / プロモーター / 転写因子 / PDE3B / promoter / insulin resistance / 分化 / RNA / cytokine / gene expression / monocytes / adipocytes / resistin / サイトカイン / 単球 / Insulin resistance / Differentiation / Adipocytes / PPAR_γ / Transcription factor / Promoter / PPARγ / gene / adipocyte / transcription / adipocyte differentiation / Phosphodiesterase / PDE / インスリン / 転写 / 脂肪分化 / ホスホジェステラーゼ / メタボリックシンドローム / アディポサイトカイン / FOXC2 / 肥満 … More
Except Principal Investigator
糖尿病 / レジスチン / SNP / インスリン抵抗性 / PDE3B / インスリン / 遺伝子 / ハプロタイプ / 2型糖尿病 / 脂肪細胞 / 環境因子 / 一般住民 / 一塩基多型 / 生活習慣病 / 高感度ELISA / GLUT4 / Diabetes / insulin / 14-3-3β / 相互作用 / insulin resistance / 多型 / 感受性遺伝子 / Insulin / Akt / 家族性地中海熱 / インフラマソーム / 自己炎症疾患 / GAD抗体 / HLA / resistin / 動脈硬化 / 死亡リスク / 生命予後 / 心拍変動 / 血清コルチゾール / 疫学研究 / 社会心理学的因子 / 循環器疾患 / 自律神経系機能 / コホート研究 / 脈拍変動 / 心理生理学的バイオマーカー / 予防医学 / 身体的老化マーカー / メタボローム解析 / 白血球 / NTproBNP / 心不全 / 心不全スクリーニング / 超高感度ELISA / ろ紙血 / 自己採取サンプル / 尿 / 唾液 / 受診勧奨 / オンライン診療 / 歯周病 / メタボリック症候群 / スクリーニング / 在宅 / 高感度測定系 / 遺伝疫学 / mental disorders / population based study / nitric oxide / モデルマウス / 集団ベース解析 / DDAH / 多型解析 / アミノ基転移酵素 / 精神神経疾患 / 集団ベース研究 / 遺伝子関連解析 / DDAH1 / AGXT2 / 一酸化窒素 / 認知症 / 高血圧 / AGXT2遺伝子 / メチルアルギニン / 一酸化炭素 / 難病 / コンパニオン診断 / インフラマソーム病 / 遺伝学 / 糖尿病新規発症 / メチル化 / 一塩基多型(SNP) / 頸動脈肥厚 / 血圧 / 就寝時血圧 / 起床時血圧 / 健診時血圧 / 睡眠呼吸障害 / 睡眠の質 / 頚動脈壁肥厚 / interaction / phosphorylation / adipocytes / 燐酸化 / Myofibroblasts / Retinopathy / 形質転換 / 平滑筋様細胞 / 糖尿病網膜症 / 筋線維芽細胞 / 筋繊維芽細胞 / 網膜症 / retrovirus expression system / glucose transporter / glucose transport / insulin action / レトロウィルス発現系 / 糖輸送担体 / グルコース輸送 / インスリン作用 / Haplotype / Polymorphisms / Susceptibility gene / Adipocytes / Serine phosphorylation / Interaction / Phosbodiesterase 3B / 14-3-3 β / セリン燐酸化 / phosphodiesterase 3B / transcription / adipocytokine / polymorphism / susceptibility genes / diabetes / PDE / 疾患感受性 / 転写因子 / 転写 / アディポサイトカイン / PI 3-K / adenovirus / PKCλ / PKB / PI3-K / アデノウイルス / microRNA / 1型糖尿病関連因子 / 1型糖尿病 / トルコ共和国 / トルコ / クリオピリン関連周期熱症候群 / 無細胞蛋白質合成システム / 分類 / DNA array / SNPs / Th1 / M1/M2 / マクロファージ / 免疫 / DNAメチル化 / 遺伝子発現 / DNA メチル化 / モノクロナール抗体 / ELISA / モノクローナル抗体 / 長期縦断研究 / 動脈硬化性疾患 / ゲノム / 長期縦断疫学研究 / インスリン応答性エレメント / プロモーター / 転写調節 / ヒトレジスチン / ベータセルリン / AMPキナーゼ / HNF-4α / adiponectin receptors / hepatic lipid content / UCP1 / CYP2C9 / Resistin / UCP2 / TCF7L2 / AMPK / HNF4α / CPT1A / HHEX遺伝子 / TCF7L2遺伝子 / 関連解析 / cumulative risk / KCNQ1遺伝子 / ゲノムワイド関連解析 / 遺伝因子 / 予測モデル / 候補遺伝子 / GWAS / KCNQ1 Less
  • Research Projects

    (37 results)
  • Research Products

    (134 results)
  • Co-Researchers

    (59 People)
  •  メタボローム解析による一般住民の血中老化バイオマーカーの探索と予防医学への応用

    • Principal Investigator
      高田 康徳
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Ehime University
  •  SNP配列特異的エンハンサーRNAを統合したレジスチン遺伝子発現調節機構の解明Principal Investigator

    • Principal Investigator
      大澤 春彦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Ehime University
  •  レジスチンを標的としたプロモーターSNP・白血球特異的遺伝子発現相乗効果の解明

    • Principal Investigator
      川村 良一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Ehime University
  •  A prospective study on the effect of sociopsychological biomarkers on incident diabetes and cardiovascular disease.

    • Principal Investigator
      斉藤 功
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
    • Research Institution
      Oita University
  •  Clinical laboratory test using samples self-collected at home by ultra-high sensitivity ELISA for online medical consultation

    • Principal Investigator
      Takata Yasunori
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Ehime University
  •  Allele-specific effects of promoter SNPs in regulation of the human resistin gene expressionPrincipal Investigator

    • Principal Investigator
      Osawa Haruhiko
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Ehime University
  •  Gene-environment interaction mechanisms targeting the type 2 diabetes susceptibility gene resistin

    • Principal Investigator
      Kawamura Ryoichi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Ehime University
  •  Population based study of mental disorders by nitric oxide system variants.

    • Principal Investigator
      Ueno Shuichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Ehime University
  •  The influence of resistin SNPs on glucose intolerance in general population

    • Principal Investigator
      Takata Yasunori
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Ehime University
  •  Acceleration of the definition of "inflammasome disease" based on molecular mechanism of diseases

    • Principal Investigator
      MASUMOTO Junya
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Internal medicine of the bio-information integration and related fields
    • Research Institution
      Ehime University
  •  Classification of diabetes based on high sensitivity anti-GAD antibody and HLA

    • Principal Investigator
      Hiroshi Onuma
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Tokyo Women's Medical University
      Ehime University
  •  Regulation of human resistin gene expression by SNPs determining epigenetics and environmental factorsPrincipal Investigator

    • Principal Investigator
      Osawa Haruhiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  A prospective study in order to identify inflammatory attack triggers in autoinflammatory diseases

    • Principal Investigator
      Masumoto Junya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Ehime University
  •  A comparative study of intrinsic factor activating inflammasome between Turkey and Japan

    • Principal Investigator
      Masumoto Junya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene and public health
    • Research Institution
      Ehime University
  •  Elucidation of the mechanisms of the association between resistin and type 1 diabetes. – The establishment of novel laboratory procedure for prediction of insulin dependent diabetes mellitus -

    • Principal Investigator
      TAKATA YASUNORI
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Ehime University
  •  HLA and classification of diabetes

    • Principal Investigator
      Onuma Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Ehime University
  •  Regulation of the human resistin gene expression by SNPs, epigenetics, and environmental factorsPrincipal Investigator

    • Principal Investigator
      OSAWA HARUHIKO
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  Impact of Sleep Disordered Breathing and Home and Office Blood Pressure on Carotid Arterial Wall Thickness: the Toon Health Study

    • Principal Investigator
      Eguchi Eri
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Epidemiology and preventive medicine
    • Research Institution
      Okayama University
      Ehime University
  •  The influence of resistin related immune-system on the pathophysiology of diabetes

    • Principal Investigator
      TAKATA Yasunori
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Ehime University
  •  Establishment of anti human monoclonal antibody clones using cell-free protein translation system and development of automatic measurement system of human resistin.

    • Principal Investigator
      NISHIDA Wataru
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Ehime University
  •  Regulation of human resistin gene expression integrating the DNA methylation

    • Principal Investigator
      ONUMA Hiroshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  Epigenetic models of insulin resistance targeting the human resistin genePrincipal Investigator

    • Principal Investigator
      OSAWA Haruhiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  Longitudinal genetic epidemiological study for cardiovascular diseases based on Japanese general population participated in medical check-up process of Ehime University Anti-aging doc.

    • Principal Investigator
      TABARA Yasuharu
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Public health/Health science
    • Research Institution
      Kyoto University
      Ehime University
  •  Application of Resistin SNP to Order-made Medicine of Metabolic SyndromePrincipal Investigator

    • Principal Investigator
      OSAWA Haruhiko, 牧野 英一
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  Regulation of human resistin gene expression by insulin through functional SNP

    • Principal Investigator
      ONUMA Hiroshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  Identification and clinical application of susceptibility genes for diabetes mellitus.

    • Principal Investigator
      KASUGA Masato
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Identification of transcription activators of resistin gene with type 2 diabetes susceptibility promoter SNPPrincipal Investigator

    • Principal Investigator
      OSAWA Haruhiko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  The cloning and characterization of the 50 kDa protein which is associated with PDE3B and phosphorylated by insulin

    • Principal Investigator
      MAKINO Hideichi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  脂肪細胞褐色化転換転写因子"FOXC2"による脂肪細胞形質決定因子の体系的同定Principal Investigator

    • Principal Investigator
      大澤 春彦
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Ehime University
  •  Identification of novel factors regulating "insulin-responsiveness" by retrovirus expression system.

    • Principal Investigator
      HASHIRAMOTO Mitsuru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      EHIME UNIVERSITY
  •  Molecular mechanism of proliferation of myofibroblasts in diabetic retinopathy

    • Principal Investigator
      NISHIDA Wataru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  The analysis of a newly identified molecule which interacts with phosphodiesterase3B insulin-dependently

    • Principal Investigator
      ONUMA Hiroshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  Whole genome association study on type 2 diabetes susceptibility genes using microsatellite markers and DNA pool

    • Principal Investigator
      MAKINO Hideichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  Identification of novel adipocyte-specific factors regulating PDE3B gene transcription different from PPAR_γPrincipal Investigator

    • Principal Investigator
      OSAWA Haruhiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University
  •  Identification of diabetes-related genes

    • Principal Investigator
      HIDEICHI Hideichi
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Ehime University
  •  Analysis of insulin-induced PDE kinase activation by gene transfer using adenovirus vector

    • Principal Investigator
      MAKINO Hideichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University School of Medicine
  •  Identification of Activating Factors for Phosphodiesterase 3B Gene TranscriptionPrincipal Investigator

    • Principal Investigator
      HARUHIKO Osawa
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Ehime University School of Medicine

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All Journal Article Presentation Book

  • [Book] 検査ONE POINTインスリン抵抗性の評価検査2012

    • Author(s)
      西田 亙, 大澤 春彦
    • Publisher
      SRL宝函
    • Data Source
      KAKENHI-PROJECT-22590530
  • [Book] 血糖自己測定の指導法,糖尿病最新の治療2010~20122010

    • Author(s)
      西田亙, 大澤春彦
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-22590530
  • [Book] 血糖自己測定の指導法, 糖尿病最新の治療2010

    • Author(s)
      西田亙, 大澤春彦
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-22590530
  • [Book] 新時代の糖尿病学22008

    • Author(s)
      大澤春彦、牧野英一
    • Total Pages
      655
    • Publisher
      日本臨床
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Book] 糖尿病学 基礎と臨床, レジスチン2007

    • Author(s)
      大澤春彦, 他
    • Total Pages
      1400
    • Publisher
      西村書店
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] ヒトの血中レジスチン調節機構の解明 SNP,epigenetics,遺伝子・環境因子相互作用と体質2024

    • Author(s)
      大澤 春彦
    • Journal Title

      日本体質医学会雑誌

      Volume: 1 Pages: 55-61

    • Data Source
      KAKENHI-PROJECT-23K07970
  • [Journal Article] Pulse rate variability and health-related quality of life assessment with the Short Form-8 Japanese version in the general Japanese population2024

    • Author(s)
      Saito Isao、Maruyama Koutatsu、Yamauchi Kanako、Funakoshi Yayoi、Kato Tadahiro、Kawamura Ryoichi、Takata Yasunori、Osawa Haruhiko
    • Journal Title

      Scientific Reports

      Volume: 14 Issue: 1 Pages: 4157-4157

    • DOI

      10.1038/s41598-024-54748-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K21520
  • [Journal Article] Positive association between serum resistin and smoking was strongest in homozygotes of the G-A haplotype at c.-420 C>G and c.-358 G>A in RETN promoter: the Toon Genome Study2023

    • Author(s)
      Hadate Toshimi、Kawamura Ryoichi、Tabara Yasuharu、Maruyama Koutatsu、Takakado Misaki、Ikeda Yosuke、Ohashi Jun、Takata Yasunori、Saito Isao、Osawa Haruhiko
    • Journal Title

      Journal of Human Genetics

      Volume: 68 Issue: 11 Pages: 745-750

    • DOI

      10.1038/s10038-023-01176-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08910
  • [Journal Article] Association of a SNP in the IAPP gene and hyperglycemia on β-cell dysfunction in type 2 diabetes: the Toon Genome Study.2021

    • Author(s)
      Kawamura R, Tabara Y, Takata Y, Maruyama K, Takakado M, Hadate T, Matsushita Y, Sano M, Makino H, Saito I, Kanatsuka A, and Osawa H.
    • Journal Title

      Diabetol Int

      Volume: 13 Issue: 1 Pages: 201-208

    • DOI

      10.1007/s13340-021-00523-4

    • NAID

      40022802956

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07868
  • [Journal Article] Simple and non-invasive screening method for diabetes based on myoinositol levels in urine samples collected at home2020

    • Author(s)
      Takakado Misaki、Takata Yasunori、Yamagata Fumio、Yaguchi Michiko、Hiasa Go、Sato Sumiko、Funada Jun-ichi、Kawazu Shoji、Osawa Haruhiko
    • Journal Title

      BMJ Open Diabetes Research & Care

      Volume: 8 Issue: 1 Pages: e000984-e000984

    • DOI

      10.1136/bmjdrc-2019-000984

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08985
  • [Journal Article] Ratios of serum eicosapentaenoic acid to arachidonic acid and docosahexaenoic acid to arachidonic acid were inversely associated with serum resistin levels: The Hisayama Study2019

    • Author(s)
      Higashioka Mayu、Hirakawa Yoichiro、Kawamura Ryoichi、Honda Takanori、Hata Jun、Yoshida Daigo、Takata Yasunori、Kitazono Takanari、Osawa Haruhiko、Ninomiya Toshiharu
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 11 Issue: 2 Pages: 482-489

    • DOI

      10.1111/jdi.13129

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K17925, KAKENHI-PROJECT-17K08985, KAKENHI-PROJECT-17K09113
  • [Journal Article] Variants in the BACH2 and CLEC16A gene might be associated with susceptibility to insulin‐triggered type1 diabetes2019

    • Author(s)
      Onuma Hiroshi、Kawamura Ryoichi、Tabara Yasuharu、Yamashita Masakatsu、Ohashi Jun、Kawasaki Eiji、Imagawa Akihisa、Yamada Yuya、Chujo Daisuke、Takahashi Kenji、Suehiro Tadashi、Takata Yasunori、Osawa Haruhiko、Makino Hideichi
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 10 Issue: 6 Pages: 1447-1453

    • DOI

      10.1111/jdi.13057

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H05036, KAKENHI-PROJECT-17K08985
  • [Journal Article] An inverse association between serum resistin levels and n-3 polyunsaturated fatty acids intake was strongest in the SNP-420 G/G genotype in the Japanese cohort: The Toon Genome Study.2018

    • Author(s)
      Noumi Y. Kawamura R. Tabara Y. Maruyama K. Takata Y. Nishida W. Okamoto A. Nishimiya T. Onuma H. Saito I. Tanigawa T. Osawa H.
    • Journal Title

      Clin Endocrinol

      Volume: 88 Issue: 1 Pages: 51-57

    • DOI

      10.1111/cen.13500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04123, KAKENHI-PROJECT-17K08985, KAKENHI-PROJECT-16K09754
  • [Journal Article] Association Between Heart Rate Variability and Home Blood Pressure: The Toon Health Study.2018

    • Author(s)
      Saito I, Takata Y, Maruyama K, Eguchi E, Kato T, Shirahama R, Tomooka K, Kawamura R, Sano M, Tabara Y, Osawa H, Tanigawa T.
    • Journal Title

      Am J Hypertens.

      Volume: 31 Issue: 10 Pages: 1120-1126

    • DOI

      10.1093/ajh/hpy100

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08985, KAKENHI-PROJECT-16K09072
  • [Journal Article] IAPP/amylin deposition, which is correlated with expressions of ASC and IL-1β in β-cells of Langerhans’ islets, directly initiates NLRP3 inflammasome activation2018

    • Author(s)
      Morikawa S, Kaneko N, Okumura C, Taguchi H, Kurata M, Yamamoto T, Osawa H, Nakanishi A, Zako T, Masumoto J.
    • Journal Title

      International Journal of Immunopathology and Pharmacology

      Volume: 32 Pages: 205873841878874-205873841878874

    • DOI

      10.1177/2058738418788749

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04656, KAKENHI-PROJECT-17K19685, KAKENHI-PROJECT-18H00464
  • [Journal Article] DIHSと劇症1型糖尿病2016

    • Author(s)
      大沼 裕, 牧野 英一, 大澤春彦
    • Journal Title

      日本体質医学会雑誌

      Volume: 78 Pages: 1-6

    • NAID

      40020795429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460690
  • [Journal Article] 1型糖尿病発症と薬剤 DIHSと1型糖尿病2015

    • Author(s)
      牧野 英一, 大沼 裕, 大澤春彦
    • Journal Title

      月刊糖尿病

      Volume: 7 Pages: 39-47

    • Data Source
      KAKENHI-PROJECT-25460690
  • [Journal Article] Relatively lower central aortic pressure in patients with impaired insulin sensitivity and resistance: the Toon Health Study2012

    • Author(s)
      Tabara Y, Saito I, Nishida W, Kohara K, Sakurai S, Kawamura R, Onuma H, Takata Y, Osawa H, Miki T, Tanigawa T
    • Journal Title

      J Hypertens

      Volume: 29 Pages: 1948-1954

    • Data Source
      KAKENHI-PROJECT-22590530
  • [Journal Article] 血中レジスチン規定因子としての SNP の意義2012

    • Author(s)
      大沼裕, 大澤春彦
    • Journal Title

      愛媛医学

      Volume: 31巻 4号 Pages: 161-165

    • Data Source
      KAKENHI-PROJECT-22590985
  • [Journal Article] Association of hematological parameters with insulin resistance, insulin sensitivity, and asymptomatic cerebrovascular damage: The J-SHIP Toon Health Study2012

    • Author(s)
      Tabara Y, Igase M, Saito I, Nishida W, Kohara K, Sakurai S, Kawamura R, Okada Y, Hitsumoto S, Onuma H, Nagai T, Takata Y, Uetani E, Takita R, Kido T, Ochi N, Osawa H, Tanigawa T, Miki T
    • Journal Title

      Clin Hemorheol Microcirc

      Volume: in press Issue: 3 Pages: 297-311

    • DOI

      10.3233/ch-2012-1634

    • NAID

      120005366009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390185, KAKENHI-PROJECT-23390188, KAKENHI-PROJECT-23590796, KAKENHI-PROJECT-23659382, KAKENHI-PROJECT-25670353
  • [Journal Article] 検査ONE POINTインスリン抵抗性の評価検査2012

    • Author(s)
      西田亙, 大澤春彦
    • Journal Title

      SRL宝函

      Volume: 32 Pages: 43-46

    • Data Source
      KAKENHI-PROJECT-22590530
  • [Journal Article] 遺伝子-遺伝子相互作用2011

    • Author(s)
      大沼裕、大澤春彦
    • Journal Title

      プラクティス

      Volume: 別冊 Pages: 134-136

    • Data Source
      KAKENHI-PROJECT-22590985
  • [Journal Article] 生活習慣病における遺伝因子-2型糖尿病を中心に-2011

    • Author(s)
      大澤春彦
    • Journal Title

      日本体質医学会雑誌

      Volume: 73 Pages: 41-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591141
  • [Journal Article] Relatively lower central aortic pressure in patients with impaired insulin sensitivity and resistance: the Toon Health Study2011

    • Author(s)
      Tabara Y, Saito I, Nishida W, Kohara K, Sakurai S, Kawamura R, Onuma H, Takata Y, Osawa H, Miki T, Tanigawa T
    • Journal Title

      J Hypertens

      Volume: 29 Issue: 10 Pages: 1948-54

    • DOI

      10.1097/hjh.0b013e32834abd06

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390185, KAKENHI-PROJECT-22390134
  • [Journal Article] ヒトにおけるレジスチンの意義2011

    • Author(s)
      大沼裕、大澤春彦
    • Journal Title

      実験医学

      Volume: 29 Pages: 715-721

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591141
  • [Journal Article] Genotype risk score of common susceptible variants for prediction of type 2 diabetes mellitus in Japanese: the Shimanami Health Promoting Program (J-SHIPP study). Development of type 2 diabetes mellitus and genotype risk score2011

    • Author(s)
      Tabara Y, Osawa H, Kawamoto R, Onuma H, Shimizu I, Makino H, Kohara K, Miki T
    • Journal Title

      Metabolism

      Volume: 60(11) Issue: 11 Pages: 1634-40

    • DOI

      10.1016/j.metabol.2011.03.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390185, KAKENHI-PROJECT-22659143, KAKENHI-PROJECT-23390188
  • [Journal Article] Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus.2010

    • Author(s)
      Okamoto, K., Yasuda, K. (16番目), Osawa, H. (17), Nanjo, K. (18), Kadowaki, T. (19), Kasuga, M. (20), ほか19名
    • Journal Title

      Am J Hum Genet 86(1)

      Pages: 54-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] A at single nucleotide polymorphism-358 is required for G at -420 to confer the highest plasma resistin in the general Japanese population2010

    • Author(s)
      Onuma H, Tabara Y, Kawamura R, Tanaka T, Ohashi J, Nishida W, Takata Y, Ochi M, Yamada K, Kawamoto R, Kohara K, Miki T, Makino H, Osawa H
    • Journal Title

      PLoS One

      Volume: 5 Issue: 3 Pages: e9718-e9718

    • DOI

      10.1371/journal.pone.0009718

    • Data Source
      KAKENHI-PROJECT-20390185
  • [Journal Article] The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population2010

    • Author(s)
      Onuma H, Tabara Y, Kawamoto R, Shimizu I, Kawamura R, Takata Y, Nishida W, Ohashi J, Miki T, Kohara K, Makino H, Osawa H
    • Journal Title

      J Hum Genet

      Volume: 55 Issue: 9 Pages: 600-604

    • DOI

      10.1038/jhg.2010.75

    • NAID

      10030736734

    • Data Source
      KAKENHI-PROJECT-20390185
  • [Journal Article] Is rs34861192 or rs1862513 a more promising variant for determining plasma resistin in an aged Japanese population?2010

    • Author(s)
      Osawa H, et al.
    • Journal Title

      Diabetologia.

      Volume: 53 Pages: 795-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Journal Article] レジスチンの臨床的意義2010

    • Author(s)
      大沼裕, 大澤春彦
    • Journal Title

      Annual Review 糖尿病・代謝・内分泌 2010巻

      Pages: 138-144

    • Data Source
      KAKENHI-PROJECT-21591141
  • [Journal Article] Is rs34861192 or rs1862513 a more promising variant for determining plasma resistin in an aged Japanese population?2010

    • Author(s)
      Osawa, H., Tabara, Y., Ohashi, J., Kawamura, R., Onuma, H., and Makino, H.
    • Journal Title

      Diabetologia

      Volume: 53 Pages: 795-797

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591141
  • [Journal Article] レジスチン2010

    • Author(s)
      大沼裕, 大澤春彦
    • Journal Title

      日本臨末 増刊号2 肥満症 68巻

      Pages: 100-104

    • NAID

      40020522158

    • Data Source
      KAKENHI-PROJECT-21591141
  • [Journal Article] Is rs34861192 or rs1862513 a more promising variant for determining plasma resistin in an aged Japanese population?2010

    • Author(s)
      Osawa H, Tabara Y, Ohashi J, Kawamura R, Onuma H, Makino H
    • Journal Title

      Diabetologia.

      Volume: 53 Issue: 4 Pages: 795-797

    • DOI

      10.1007/s00125-010-1665-4

    • Data Source
      KAKENHI-PROJECT-20390185
  • [Journal Article] レジスチン2010

    • Author(s)
      大沼裕, 大澤春彦
    • Journal Title

      日本臨床

      Volume: 68(増刊号2) Pages: 100-104

    • NAID

      40020522158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591141
  • [Journal Article] A at single nucleotide polymorphism-358 is required for G at-420 to confer the highest plasma resistin in the general Japanese population2010

    • Author(s)
      Onuma, H., Tabara, Y., Kawamura, R., Tanaka, T., Ohashi, J., Nishida, W., Takata, Y., Ochi, M., Yamada, K., Kawamoto, R., Kohara, K., Miki, T., Makino, H., and Osawa, H.
    • Journal Title

      PLoS ONE

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591141
  • [Journal Article] レジスチンの臨床的意義2010

    • Author(s)
      大沼裕, 大澤春彦
    • Journal Title

      Annual Review糖尿病・代謝・内分泌

      Pages: 138-144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591141
  • [Journal Article] The PPARγPro12Ala Pro/Pro and resistin SNP-420G/G genotypes are synergistically associated with plasma resistin in the Japanese general population.2009

    • Author(s)
      Osawa, H., Makino, H. (11番目), ほか10名
    • Journal Title

      Clin Endocrinol 71

      Pages: 341-345

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] The PPAR γ Pro12Ala Pro/Pro and resistin SNP-420G/G genotypes are synergistically associated with plasma resistin in the Japanese general population.2009

    • Author(s)
      Osawa H, et al
    • Journal Title

      Clin Endocrinol 71

      Pages: 341-345

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening.2009

    • Author(s)
      Tabara, Y., Osawa, H. (2番目), Makino, H. (8人中8番目), ほか5名
    • Journal Title

      Diabetes 58(2)

      Pages: 493-498

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Construction of a prediction model for type 2 diabetes mellitus in the Japanese population based on 11 genes with strong evidence of the association.2009

    • Author(s)
      Miyake, K., Yasuda, K. (4番目), Osawa, H. (6番目), Makino, H. (32番目), Nanjo, K. (33), Kadowaki, T. (34), Kasuga, M. (35人中35番目), ほか28名
    • Journal Title

      J Hum Genet 54(4)

      Pages: 236-41

    • NAID

      10030730081

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening.2009

    • Author(s)
      Tabara Y, Osawa H, Kawamoto R, Onuma H, Shimizu I, Miki T, Kohara K, Makino H.
    • Journal Title

      Diabetes. 58

      Pages: 493-498

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Journal Article] Reduced high-molecular-weight adiponectin and elevated high-sensitivity C-reactive protein are synergistic risk factors for metabolic syndrome in a large-scale middle-aged to elderly population: the Shimanami Health Promoting Program Study2008

    • Author(s)
      Tabara Y, Osawa H, Kawamoto R, Tachibana-Iimori R, Yamamoto M, Nakura J, Miki T, Makino H, Kohara K
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 93 Issue: 3 Pages: 715-722

    • DOI

      10.1210/jc.2007-0397

    • Data Source
      KAKENHI-PROJECT-20390185
  • [Journal Article] Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.2008

    • Author(s)
      Yasuda, K., Miyake, K., Osawa, H. (5番目), Makino, H. (44番目), Nanjo, K. (45), Kadowaki, T. (46), Kasuga, M. (47人中47番目), ほか40名
    • Journal Title

      Nature Genetics 40(9)

      Pages: 1092-1097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] The G/G genotype of single nucleotide polymorphism at -1066 of c-Jun N-terminal kinase 1 gene (MAPK8) does not affect type 2 diabetes susceptibility despite the specific binding of AP2a.2008

    • Author(s)
      Osawa, H., Makino, H. (15人中15番目), ほか13名
    • Journal Title

      Clin Endocrinol 69

      Pages: 36-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] レジスチン-ヒトのインスリン抵抗性における意義-2008

    • Author(s)
      大澤春彦、牧野英一
    • Journal Title

      臨床化学 37

      Pages: 258-263

    • NAID

      10025632074

    • Data Source
      KAKENHI-PROJECT-19591055
  • [Journal Article] The G/G genotype of single nucleotide polymorphism at -1066 of c-Jun N-terminal kinase 1 gene (MAPK8) does not affect type 2 diabetes susceptibility despite the specific binding of AP2 α2008

    • Author(s)
      Osawa, H., et. al.
    • Journal Title

      Clin Endocrinol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] No association of INSIG2 gene rs7566605 polymorphism with being overweight in Japanese population2008

    • Author(s)
      Tabara Y, Kawamoto R, Osawa H, Nakura J, Makino H, Miki T, Kohara K
    • Journal Title

      Obesity 16

      Pages: 211-215

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Journal Article] Reduced high-molecular-weight adiponectin and elevated high-sensitivity C-reactive protein are synergistic risk factors for metabolic syndrome in a large-scale middle-aged to elderly population2008

    • Author(s)
      Tabara Y, Osawa H, Kawamoto R, Tachibana R, Yamamoto M, Nakura J, Miki T, Makino H, Kohara K.
    • Journal Title

      J Clin Endocrinol Metab. 93

      Pages: 715-722

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Journal Article] Serum resistin is positively associated with the accumulation of metabolic syndrome factors in type 2 diabetes2008

    • Author(s)
      Osawa, H., et. al.
    • Journal Title

      Clin Endocrinol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] No association between INSIG2 Gene rs7566605 polymorphism and being overweight in Japanese population2008

    • Author(s)
      Tabara Y, Kawamoto R, Osawa H, Nakura J, Makino H, Miki T, Kohara K
    • Journal Title

      Obesity

      Volume: 16 Issue: 1 Pages: 211-215

    • DOI

      10.1038/oby.2007.25

    • Data Source
      KAKENHI-PROJECT-20390185
  • [Journal Article] レジスチン-ヒトのインスリン抵抗性における意義-2008

    • Author(s)
      大澤春彦, 他
    • Journal Title

      臨床化学 37

      Pages: 258-263

    • NAID

      10025632074

    • Data Source
      KAKENHI-PROJECT-19591055
  • [Journal Article] Resistin, glomerular filtration rate, and insulin resistance.2008

    • Author(s)
      Tabara Y, Igase M, Osawa H, Makino H, Miki T, Kohara K.
    • Journal Title

      Hypertension 51(ell)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Journal Article] Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4, 087 Japanese subjects.2008

    • Author(s)
      Miyake, K., Yasuda, K. (4番目), Osawa, H. (5番目), Makino, H. (20番目), Nanjo, K. (21), Kadowaki, T. (22), Kasuga, M. (23人中23番目), ほか16名
    • Journal Title

      J Hum Genet 53(2)

      Pages: 174-180

    • NAID

      10021248002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Resistin, glomerular filtration rate, and insulin resistance2008

    • Author(s)
      Tabara Y, Igase M, Osawa H, Makino H, Miki T, Kohara K
    • Journal Title

      Hypertension

      Volume: 51 Issue: 2

    • DOI

      10.1161/hypertensionaha.107.102046

    • Data Source
      KAKENHI-PROJECT-20390185
  • [Journal Article] Serum resistin is associated with the severity of microangiopathies in type 2 diabetes.2007

    • Author(s)
      Osawa H. et al.
    • Journal Title

      Biochem Biophys Res Commun 355

      Pages: 342-346

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590938
  • [Journal Article] Frequency of the G/G genotype of resistin single nucleotide polymorphism at -420 appears to be increased in younger-onset type 2 diabetes.2007

    • Author(s)
      Ochi, M., Osawa, H., Kadowaki, T. (13番目), Kasuga, M. (15番目), Makino, H. (16人中16番目), ほか11名
    • Journal Title

      Diabetes 56

      Pages: 2834-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Serum resistin is associated with the severity of microangiopathies in type 2 diabetes.2007

    • Author(s)
      Osawa H., et al.
    • Journal Title

      Biochem Biophys Res Commun 355

      Pages: 342-346

    • Data Source
      KAKENHI-PROJECT-17590938
  • [Journal Article] Serum resistin is associated with the severity of microangiopathies in type 2 diabetes.2007

    • Author(s)
      Osawa H..et al.
    • Journal Title

      Biochem Biophys Res Commun 355

      Pages: 342-346

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590938
  • [Journal Article] Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL, and high sensitivity CRP in the Japanese general population2007

    • Author(s)
      Osawa, H., Makino, H. (12人中12番目), ほか10名
    • Journal Title

      Diabetes Care 30

      Pages: 1501-1506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Serum resistin is associated with the severity of microangiopathies in type 2 diabetes.2007

    • Author(s)
      Osawa, H.
    • Journal Title

      Biochem Biophys Res Commun 355

      Pages: 342-346

    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL, and high sensitivity CRP in the Japanese general population2007

    • Author(s)
      Osawa, H., et. al.
    • Journal Title

      Diabetes Care 30

      Pages: 1501-1506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] A newly identified 50 kDa protein which is associated with phosphodiesterase 3B is phosphorylated by insulin in rat adipocytes.2005

    • Author(s)
      Onuma, H., Osawa, H., Makino, H., et al.
    • Journal Title

      Biochem Biophys Res Commun 337

      Pages: 976-982

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590939
  • [Journal Article] A case of fulminant type 1 diabetes associated with high titer of Coxsackie B3 virus antibody2005

    • Author(s)
      Nishida W, Hasebe S, Kawamura R, Hashiramoto M, Onuma H, Osawa H, Makino H
    • Journal Title

      Journal of the Japan Diabetes Society (in press)

    • NAID

      10016604665

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590946
  • [Journal Article] Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes.2005

    • Author(s)
      Osawa H. et al.
    • Journal Title

      Biochem Biophys Res Commun 335

      Pages: 596-602

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590938
  • [Journal Article] Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes.2005

    • Author(s)
      Osawa H..et al.
    • Journal Title

      Biochem Biophys Res Commun 335

      Pages: 596-602

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590938
  • [Journal Article] A newly identified 50 kDa protein which is associated with phosphodiesterase 3B is phosphorylated by insulin in rat adipocytes.2005

    • Author(s)
      Onuma, H., Osawa, H, Makino, H.et al.
    • Journal Title

      Biochem Biophys Res Commun 337

      Pages: 976-982

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590939
  • [Journal Article] A newly identified 50kDa protein which is associated with phosphodiesterase 3B is phosphorylated by insulin in rat adipocytes.2005

    • Author(s)
      Onuma, H., Osawa, H., Makino, H.et al.
    • Journal Title

      Biochem Biophys Res Commun 337

      Pages: 976-982

    • Data Source
      KAKENHI-PROJECT-17590939
  • [Journal Article] 発症時コクサッキーB3ウィルス中和抗体価の上昇がみられた劇症1型糖尿病の1例2005

    • Author(s)
      西田亙, 長谷部晋士, 川村良一, 柱本満, 大沼裕, 大澤春彦, 牧野英一
    • Journal Title

      糖尿病 (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590946
  • [Journal Article] Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes.2005

    • Author(s)
      Osawa, H., et al.
    • Journal Title

      Biochem Biophys Res Commun 335

      Pages: 596-602

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes2005

    • Author(s)
      Osawa H, et al.
    • Journal Title

      Biochem Biophys Res Common 335

      Pages: 596-602

    • Data Source
      KAKENHI-PROJECT-17590938
  • [Journal Article] Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes.2005

    • Author(s)
      Osawa, H et al.
    • Journal Title

      Biochem Biophys Res Commun 335

      Pages: 596-602

    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] 発病時コクサッキーB3ウィルス中和抗体価の上昇がみられた劇症1型糖尿病の1例2005

    • Author(s)
      西田亙, 長谷部晋士, 川村良一, 柱本満, 大沼裕, 大澤春彦, 牧野英一
    • Journal Title

      糖尿病 (In press)

    • Data Source
      KAKENHI-PROJECT-15590946
  • [Journal Article] Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes.2005

    • Author(s)
      Osawa H., et al.
    • Journal Title

      Biochem Biophys Res Commun 335

      Pages: 596-602

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] The G/G Genotype of a resistin single-nucleotide polymorphism at-420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/32004

    • Author(s)
      Osawa H et al.
    • Journal Title

      Am J Hum Genet 75

      Pages: 678-686

    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] The G/G Genotype of a resistin single-nucleotide polymorphism at -420increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3.2004

    • Author(s)
      Osawa, H., et al.
    • Journal Title

      Am J Hum Genet 75

      Pages: 678-686

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] The G/G Genotype of a resistin single-nucleotide polymorphism at-420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3.2004

    • Author(s)
      Osawa H et al.
    • Journal Title

      Am J Hum Genet 75

      Pages: 678-686

    • Data Source
      KAKENHI-PROJECT-16046218
  • [Journal Article] The G/G Genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3.2004

    • Author(s)
      Osawa, H., et al.
    • Journal Title

      Am J Hum Genet 75

      Pages: 678-686

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] Systematic search for single nucleon a polymorphisms in the FOXC2 gene : The absence of evidence for the association of three frequent single nucleotide polymorphisms and four common haplotypes with Japanese type 2 diabetes.2003

    • Author(s)
      Osawa, H., et al.
    • Journal Title

      Diabetes 52

      Pages: 562-567

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] Systematic search for single nucleotide polymorphisms in the FOXC2 gene : The absence of evidence for the association of three frequent single nucleotide polymorphisms and four common haplotypes with Japanese type 2 diabetes.2003

    • Author(s)
      Osawa, H., et al.
    • Journal Title

      Diabetes 52

      Pages: 562-567

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] Systematic search for single nucleotide polymorphisms in the 5' flanking region of the human phosphodiesterase 3B gene : Absence of evidence for major effects of identified polymorphisms on susceptibility to Japanese type 2 diabetes.2003

    • Author(s)
      Osawa, H., et al.
    • Journal Title

      Mol Genet Metab 79

      Pages: 43-51

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] Systematic search for single nucleotide polymorphisms in the 5 flanking region of the human phosphodiesterase 3B gene : Absence of evidence for major effects of identified polymorphisms on susceptibility to Japanese type 2 diabetes.2003

    • Author(s)
      Osawa, H., et al.
    • Journal Title

      Mol Genet Metab 79

      Pages: 43-51

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] Systematic search for single nucleotide polymorphisms in the resistin gene : The absence of evidence for the association of three identified single nucleotide polymorphisms with Japanese type 2 diabetes.2002

    • Author(s)
      Osawa, H., et al.
    • Journal Title

      Diabetes 51

      Pages: 863-866

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] Identification of novel C253Y missense and Y864X nonsense mutations in the insulin receptor gene in type A insulin resistant patients.2001

    • Author(s)
      Osawa, H., et al.
    • Journal Title

      Clin Genet 59

      Pages: 194-197

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] Systematic search for single nucleotide polymorphisms in the insulin gene : Evidence for a high frequency of g.-23T>A in Japanese subjects.2001

    • Author(s)
      Osawa, H.
    • Journal Title

      Biochem Biophys Res Commun 286

      Pages: 451-455

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] Systematic search for single nucleotide polymorphisms in the insulin gene : Evidence for a high frequency of g.-23T>A in Japanese subjects.2001

    • Author(s)
      Osawa, H., et al.
    • Journal Title

      Biochem Biophys Res Commun 286

      Pages: 451-455

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] A systematic search for single nucleotide polymorphisms (SNPs) in the insulin receptor gene : Association of an sSNP with hyperlipidemia in Japanese type 2 diabetic subjects.2001

    • Author(s)
      Osawa, H., et al.
    • Journal Title

      Clin Genet 60

      Pages: 479-481

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12204007
  • [Journal Article] The PPARy Pro12Ala Pro/Pro and resistin SNP-420 G/G genotypes are synergistically associated with plasma resistin in the Japanese general population

    • Author(s)
      Osawa H, et.al.
    • Journal Title

      Clinical Endocrinology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Presentation] 一般住民において血中レジスチンはβカロテン当量と負に関連する【東温スタディ】2023

    • Author(s)
      川村良一、丸山広達、高門美沙季、池田陽介、羽立登志美、斉藤 功、高田康徳、大澤春彦
    • Organizer
      日本糖尿病学会中国四国地方会第61回総会
    • Data Source
      KAKENHI-PROJECT-22K07399
  • [Presentation] NGTでは、レジスチンSNP-420 G/Gと喫煙はインスリン感受性低下と関連する2023

    • Author(s)
      羽立 登志美,川村 良一,田原 康玄,丸山 広達,高門 美沙季,池田 陽介, 斉藤 功,髙田 康徳,大澤 春彦
    • Organizer
      日本糖尿病学会中国四国地方会第61回総会
    • Data Source
      KAKENHI-PROJECT-20K08910
  • [Presentation] 正常型の一般住民においてレジスチンSNPは炎症を伴う腹部肥満及びインスリン抵抗性と関連する【東温ゲノムスタディ】2023

    • Author(s)
      川村良一、田原康玄、丸山広達、高門美沙季、池田陽介、羽立登志美、斉藤 功、高田康徳、大澤春彦
    • Organizer
      第66回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-22K07399
  • [Presentation] SNP-420 C/Gにおいて,Cのメチル化低値と喫煙は,血中レジスチン高値と関連する【東温ゲノムスタディ】2023

    • Author(s)
      羽立 登志美, 川村 良一, 田原 康玄, 丸山 広達, 高門 美沙季, 池田 陽介, 斉藤 功, 高田 康徳, 大澤 春彦
    • Organizer
      第66回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K08910
  • [Presentation] レジスチンSNPハプロタイプと腹部肥満はCRP高値と関連する【東温ゲノムスタディ】2022

    • Author(s)
      川村良一、田原康玄、高田康徳、丸山広達、高門美沙季、池田陽介、羽立登志美、斉藤 功、大澤春彦
    • Organizer
      日本糖尿病学会中国四国地方会第60回総会
    • Data Source
      KAKENHI-PROJECT-22K07399
  • [Presentation] 喫煙は、境界型または糖尿病において、血中レジスチン高値、及びインスリン抵抗性と関連する2022

    • Author(s)
      羽立登志美、川村良一、田原康玄、丸山広達、高門美沙季、池田陽介、斉藤 功、高田康徳、 大澤春彦
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K08910
  • [Presentation] 正常型の一般住民においてCRP高値かつ過体重は血中レジスチン高値及び5年後の耐糖能悪化と関連する2022

    • Author(s)
      川村良一、田原康玄、高田康徳、丸山広達、高門美沙季、池田陽介、羽立登志美、斎藤功、大澤春彦
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K07868
  • [Presentation] BMI25未満のNGTにおいて、レジスチンのハプロタイプはインスリン抵抗性と関連する【東温ゲノムスタディ】2021

    • Author(s)
      羽立登志美, 川村良一, 田原康玄, 丸山広達, 高門美沙季, 池田陽介, 斉藤功, 髙田康徳, 大澤春彦
    • Organizer
      日本糖尿病学会中国四国地方会第59回総会
    • Data Source
      KAKENHI-PROJECT-20K08910
  • [Presentation] 血中レジスチンはプロモーターSNPと環境因子・白血球数の相互作用によって規定される【東温ゲノムスタディ】2021

    • Author(s)
      川村良一、田原康玄、高田康徳、丸山広達、高門美沙季、池田陽介、羽立登志美、斉藤 功、大澤春彦
    • Organizer
      第6回日本糖尿病・生活習慣病ヒューマンデータ学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K07868
  • [Presentation] 血中レジスチンの変化はSNPハプロタイプと環境因子スコアにより規定される2021

    • Author(s)
      川村良一、田原康玄、高田康徳、丸山広達、高門美沙季、池田陽介、羽立登志美、斉藤 功、大澤春彦
    • Organizer
      日本糖尿病学会中国四国地方会第59回総会
    • Data Source
      KAKENHI-PROJECT-19K07868
  • [Presentation] 血中レジスチンはSNP-420/SNP-358ハプロタイプと環境因子スコアにより規定される【東温ゲノムスタディ】2021

    • Author(s)
      川村良一、高門美沙季、高田康徳、大澤春彦
    • Organizer
      第68回日本臨床検査医学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07868
  • [Presentation] SNP-420/-358 G-Aハプロタイプホモにおいて5年間の身体活動の増加は血中レジスチン低下と最も強く関連する2021

    • Author(s)
      川村良一、田原康玄、高田康徳、丸山広達、高門美沙季、池田陽介、羽立登志美、斉藤 功、大澤春彦
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K07868
  • [Presentation] レジスチンSNP-420、SNP-358の遺伝子型の組合せと喫煙は、レジスチンmRNA及び血中濃度と関連する【東温ゲノムスタディ】2021

    • Author(s)
      羽立登志美、川村良一、高田康徳、田原康玄、丸山広達、高門美沙季、池田陽介、斉藤 功、大澤春彦
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K08910
  • [Presentation] レジスチンSNP-420/SNP-358ハプロタイプと白血球数は相互に血中レジスチン高値と関連する2020

    • Author(s)
      川村良一、田原康玄、高田康徳、丸山広達、高門美沙季、池田陽介、羽立登志美、斉藤功、大澤春彦
    • Organizer
      日本糖尿病学会中国四国地方会第58回総会
    • Data Source
      KAKENHI-PROJECT-19K07868
  • [Presentation] レジスチンSNP-420/-358ハプロタイプと喫煙は相互に血中レジスチンを高める2020

    • Author(s)
      羽立登志美、川村良一、高田康徳、田原康玄、丸山広達、高門美沙季、池田陽介、斉藤 功、大澤春彦
    • Organizer
      日本糖尿病学会中国四国地方会第58回総会
    • Data Source
      KAKENHI-PROJECT-20K08910
  • [Presentation] 血中レジスチンの5年間の変化はSNP-420と環境因子スコアの相互作用により規定される【東温ゲノムスタディ】2020

    • Author(s)
      川村良一、田原康玄、高田康徳、丸山広達、高門美沙季、池田陽介、羽立登志美、西田亙、大沼裕、谷川武、斉藤功、大澤春彦
    • Organizer
      第63回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K07868
  • [Presentation] SNP-420のメチル化率は、C/C型において血中レジスチン及びインスリン抵抗性と負に関連する「東温ゲノムスタディ」2018

    • Author(s)
      羽立登志美, 川村 良一, 田原 康玄, 高田 康徳, 高門 美沙季, 丸山 広達, 西田 亙, 松下 由実, 大沼 裕, 谷川 武, 斉藤 功, 大澤 春彦
    • Organizer
      第61回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-16K09754
  • [Presentation] ヒトにおける血中レジスチン調節機構と体質2017

    • Author(s)
      大澤春彦
    • Organizer
      第67回日本体質医学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09754
  • [Presentation] 糖尿病感受性遺伝子レジスチンSNP-420のメチル化は血中レジスチンと関連する2015

    • Author(s)
      大沼 裕、田原康玄、川本龍一、門田優子、川村良一、高田康徳、西田 亙、小原克彦、牧野英一、三木哲郎、大澤 春彦
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      下関
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25461359
  • [Presentation] The DNA methylation at single nucleotide polymorphism (SNP)-420 in the human resistin gene is inversely associated with plasma resistin in the general Japanese population2015

    • Author(s)
      Hiroshi Onuma, Yasuharu Tabara, Ryoichi Kawamura, Ryuichi Kawamoto, Wataru Nishida, Yasunori Takata, Hideichi Makino, Katsuhiko Kohara, Tetsuro Miki, and Haruhiko Osawa
    • Organizer
      American Diabetes Association 75th scientific sessions
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2015-06-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461359
  • [Presentation] 一般歯科医院における血糖モニタリングの有用性 【愛媛Dental Diabetes スタディ】2012

    • Author(s)
      原瀬忠広,西田亙,重松健司,小林悟,佐古弘文,伊藤史郎,村上始,西田圭,井上洋,藤澤雅人,吉津宏,川村良一,高田康徳,大沼裕,清水恵太,浜川裕之,大澤春彦
    • Organizer
      第55回日本糖尿病学会年次学術
    • Place of Presentation
      神奈川県パシフィコ横浜
    • Year and Date
      2012-05-19
    • Data Source
      KAKENHI-PROJECT-22590530
  • [Presentation] 血中レジスチンは OGTT 正常型かつ 21≦BMI<23 の一般住民において各種インスリン指標と関連する【東温スタディ】2012

    • Author(s)
      西田亙,川村良一,高田康徳,相引真代,芝真希,能美幸信,門田優子,岡本愛,西宮達也,田原康玄,三木哲郎,斉藤功,谷川武,大沼裕,大澤春彦
    • Organizer
      第55回日本糖尿病学会年次学術集会
    • Place of Presentation
      神奈川県パシフィコ横浜
    • Year and Date
      2012-05-19
    • Data Source
      KAKENHI-PROJECT-22590530
  • [Presentation] 2型糖尿病患者入院前後における単球レジスチン遺伝子発現とシトシンメチル化の解析2012

    • Author(s)
      大沼裕、川村良一、門田優子、松下由美、相引真代、芝 真希、能美幸信、高田康徳、西田亙、牧野英一、大澤春彦
    • Organizer
      第55回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590985
  • [Presentation] ヘマトクリットとインスリン抵抗性,インスリン感受性ならびに無症候性脳血管障害との関連2012

    • Author(s)
      田原康玄・大澤春彦・伊賀瀬道也・斉藤 功・西田 亙・小原克彦・櫻井 進 川本龍一・上谷英里・櫃本真一・大沼 裕・多喜田理絵・高田康徳・永井勅久 岡田陽子・城戸知子・越智南美子・谷川武・三木哲郎
    • Organizer
      第55回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Presentation] 血中レジスチンはレジスチン遺伝子のSNP-420、SNP-358により強く規定される一方、2型糖尿病感受性遺伝子のトランス作用によっても影響される2011

    • Author(s)
      大沼裕, 田原康玄, 西田亙, 高田康徳, 大澤春彦, 他
    • Organizer
      第61回日本体質医学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21591141
  • [Presentation] 血中レジスチンはプロモーターSNPによるシス作用、および他遺伝子のトランス作用に規定される2011

    • Author(s)
      大沼 裕、田原 康玄、川村良一、田中 高志、大橋 順、西田 亙、高田 康徳、越智 正昭、山田 一哉、川本 龍一、小原 克彦、三木 哲郎、牧野 英一、大澤 春彦
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      淡路
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-22590985
  • [Presentation] 地域一般住民において血中レジスチンはOGTT 正常型かつ非肥満群のインスリン抵抗性/感受性指数と関連する 東温スタディ2011

    • Author(s)
      西田亙,川村良一,高田康徳,門田優子,星衛かよ子,大森悠史,荒川愛,谷口裕美,西宮達也,松下由美,相引真代,田原康玄,三木哲郎,斉藤功,櫻井進,谷川武,大沼裕,大澤春彦
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      北海道札幌市
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-22590530
  • [Presentation] 一般地域住民においてレジスチンは一塩基多型(SNP)-420及びSNP-358は代謝関連の量的形質とは関連しない2011

    • Author(s)
      大澤春彦, 他
    • Organizer
      弟53回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Presentation] Relatively lower central aortic pressure in subjects with impaired insulin sensitivity and resistance: The Toon Health Study2011

    • Author(s)
      Tabara Y, Saito I, Nishida W, Kohara K, Sakurai S, Kawamura R, Onuma H, Takata Y, Osawa H, Miki T, Tanigawa T
    • Organizer
      Council for High Blood Pressure Research
    • Place of Presentation
      Orlando
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Presentation] 生活習慣病における遺伝因子-2型糖尿病を中心に-2010

    • Author(s)
      大澤春彦
    • Organizer
      第60回日本体質医学会総会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-21591141
  • [Presentation] インスリン投与を契機に 2型から 1 型糖尿病に転換した 6 症例のインスリン遺伝子と膵島関連ペプチドに対する T 細胞反応性の解析2010

    • Author(s)
      西田亙,森山啓明,永田正男,中村舞,今川彰久,花房俊昭,高橋健二,末廣正,山田祐也,中條大輔,川村良一,高田康徳,大沼裕,大澤 春彦,牧野英一
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      ホテルグランビア岡山
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-22590530
  • [Presentation] 血中レジスチンは全ゲノム関連解析(GWAS)で同定された2型糖尿病感受性一塩基多型(SNP)THADAと関連する2010

    • Author(s)
      大澤春彦, 他
    • Organizer
      弟53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Presentation] Relevance of resistin in human insulin resistance2009

    • Author(s)
      Hiroshi Onuma, Haruhiko Osawa et al
    • Organizer
      The 2^<nd> Insulin resistance in metabolic disease forum
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2009-10-31
    • Data Source
      KAKENHI-PROJECT-21591141
  • [Presentation] 一般住民において、PPAR γ Pro12Ala Pro/Pro型とレジスチンSNP-426G/G型は血中レジスチンと相乗的に関連する2009

    • Author(s)
      大澤春彦, 他
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-23
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Presentation] 2型糖尿病においで血中レジスチンはメタボリックシンドローム因子数と正に関連する2008

    • Author(s)
      大澤春彦 他
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Presentation] 2型糖尿病において血中レジスチンはメタボリックシンドローム因子数と正に関連する2008

    • Author(s)
      大澤春彦, 他
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19591055
  • [Presentation] Reduced high-molecular weight adiponectin and elevated hsCRP are synergistic risk factors for metabolic syndrome in a large scale middle-aged to elderly population : The J-SHIPP study2008

    • Author(s)
      Tabara Y, Osawa H, Kawamoto R, Tachibana R, Yamamoto M, Nakura J, Miki T, Makino H, Kohara K
    • Organizer
      22nd Scientific Meeting, the International Society of Hypertension
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Presentation] メタボリックシンドロームに対する高分子量アディポネクチンと高感度CRPとの相乗的相関2008

    • Author(s)
      田原康玄, 大澤春彦, 川本龍一, 名倉 潤, 三木哲郎, 牧野英一, 小原克彦
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Presentation] Resistin, GFR and insulin resistance2008

    • Author(s)
      Tabara Y, Igase M, Osawa H, Makino H, Miki T, Kohara K
    • Organizer
      22nd Scientific Meeting, the International Society of Hypertension
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-20390185
  • [Presentation] 2 型糖尿病において血中レジスチンはメタボリックシンドローム因子数と正に関連する2008

    • Author(s)
      大澤春彦、西田亙、高田康徳、牧野英一, 他
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19591055
  • [Presentation] ヒトのインスリン抵抗性におけるレジスチンの意義2008

    • Author(s)
      大澤春彦、牧野英一, 他
    • Organizer
      第42回糖尿病学の進歩
    • Place of Presentation
      高松
    • Data Source
      KAKENHI-PROJECT-19591055
  • [Presentation] ヒトのインスリン抵抗性におけるレジスチンの意義2008

    • Author(s)
      大沼裕、大澤春彦、牧野英一、他
    • Organizer
      第53回日本臨床医学会中国・四国支部総会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-19599016
  • [Presentation] ヒトのインスリン抵抗性におけるレジスチシの意義2008

    • Author(s)
      大澤 春彦, 他
    • Organizer
      第42回糖尿病学の進歩
    • Place of Presentation
      高松
    • Data Source
      KAKENHI-PROJECT-19591055
  • [Presentation] Serum resistin is associated with multiple factors related to metabolic syndronie in type 2 diabetes.2007

    • Author(s)
      Osawa, H., et. al.
    • Organizer
      American Diabetes Association 67th Scientific Sessions
    • Place of Presentation
      Chicago, IL, USA
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Presentation] 一般住民において、血中レジスチンは、SNP-420により主に規定され、インスリン抵抗性、低HDL、高感度CRPと関連する2007

    • Author(s)
      大澤春彦, 他
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Presentation] 血中レジスチンと糖尿病感受性遺伝子レジスチンSNP-420のメチル化との関連

    • Author(s)
      大沼 裕、田原 康玄、門田 優子、川本 龍一、小原 克彦、三木 哲郎、川村 良一 高田 康徳、西田 亙、牧野 英一、大澤 春彦
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-25461359
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