Yamamoto Kazuhiro 山本一博

… Alternative Names

YAMAMOTO Kazuhiro 山本一博

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Researcher Number	90303966
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立循環器病研究センター, 病院, 病院長
Affiliation (based on the past Project Information) *help	2011 – 2023: 鳥取大学, 医学部, 教授 2013: 鳥取大学, 医学系研究科, 教授 2007 – 2010: 大阪大学, 臨床医工学融合研究教育センター, 特任教授(常勤) 2005: Osaka University, Center for Advanced Medical Engineering and Information, Specially Appointed Associate Professor, 臨床医工学融合研究教育センター, 特任助教授 2004: Osaka University, School of Medicine, Assistant Professor, 医学研究科, 助手 … More 2003 – 2004: 大阪大学, 医学系研究科, 助手 1999: Osaka University Graduate School of Medicine, Assistant Professor, 医学系研究科, 助手 1998: 大阪大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine / Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine / Medical systems / Basic Section 53020:Cardiology-related / Medical systems / Eating habits / Circulatory organs internal medicine / Rehabilitation science/Welfare engineering
Keywords	Principal Investigator 心不全 / カルニチン / うつ / 横隔膜 / ダイナペニア / フレイル / 循環器・高血圧 / エゴ / 患者教育 / ego … More / Remodeling / Cardiac Hypertrophy / Heart Failure / リモデリング / 心筋肥大 / 拡張不全 … More Except Principal Investigator 心不全 / ASK1 / レニン・アンジオテンシン系 / 拡張不全 / 拡張機能 / 超音波 / 連携パス / 学習 / 効率性 / 情報共有 / 介護 / 医療 / 地域連携 / 検査・診断システム / 高齢者心不全 / 低容量運動負荷心エコー図検査 / 心エコー図検査 / 左室駆出率が保持された心不全 / 左房機能 / 大動脈弁狭窄症 / 味覚 / 味覚異常 / ポリファーマシ / 味覚障害 / ポリファーマシー / apoptosis / reactive oxygen species / heart failure / 心不全モデル動物 / 細胞死 / 遺伝子治療 / アポトーシス / 活性酸素種 / Ultrasound / Remodeling / Cardiac Hypertrophy / Heart Failure / 細胞外マトリックス / 組織性状診断 / renin-angiotensin system / fibrosis / hypertrophy / hypertension / isolated diastolic heart failure / 線維化 / 心肥大 / 高血圧 / HFpEF / 呼吸筋 / 腎血流ドプラ / 機能的腎予備力 / 腎予備力 / 心腎連関 / 内因性ステロイド / 食塩感受性 Less

Exploratory research to elucidate the molecular mechanisms by which depression makes heart failure more severe and to reconstruct heart failure treatment strategies.Principal Investigator
- Principal Investigator
  
  山本一博
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tottori University
Study for the development of learning programme for heart failure community collaboration.
- Principal Investigator
  
  KINUGASA Yoshiharu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tottori University
Investigation about nteraction among carnitine deficiency, dynapenia and diaphragm muscle dysfunction for the effective nutritional intervention in heart failurePrincipal Investigator
- Principal Investigator
  
  Yamamoto Kazuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tottori University
clinical characteristics and prognosis of taste disorders in heart failure patients
- Principal Investigator
  
  KINUGASA YOSHIHARU
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Tottori University
Utility of low-dose exercise echocardiography for predicting outcome in the patient with HFpEF
- Principal Investigator
  
  Haruki Nobuhiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  Tottori University
investigation about relation between patient's ego and achievement of patient education in heart failure: in pursuit of efficient patient educationPrincipal Investigator
- Principal Investigator
  
  Yamamoto Kazuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Tottori University
Effect of inspiratory muscle training in patients with heart failure with preserved ejection fraction
- Principal Investigator
  
  Kinugasa Yoshiharu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Tottori University
Effects of L-carnitine on cardiac and skeletal muscle function in patients with heart failure and preserved ejection fractionPrincipal Investigator
- Principal Investigator
  
  Yamamoto Kazuhiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Tottori University
The mechanism of cardio-renal interaction in heart failure-the approach from functional renal reserve-
- Principal Investigator
  
  MANO Toshiaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
The role of salt sensitivity in the development of heart failure with preserved ejection fraction and the relation of intrinsic steroids
- Principal Investigator
  
  SAKATA Yasushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
new method to evaluate diastolicfunction using echocardiography
- Principal Investigator
  
  SAKATA Yasushi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  Osaka University
Elucidation of a role of ASK1 in the pathogenesis of heart failure and its application to therapeutics
- Principal Investigator
  
  OTSU Kinya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Ultrasound imaging of extracellular matrix remodeling for assessing congestive heart failure
- Principal Investigator
  
  MASUYAMA Tohru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Hyogo College of Medicine
  Osaka University
Gene expression profiling in hypertrophied heart as the determinant of phenotype of heart failurePrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Kazuhiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Examination of the mechanism of the transition to isolated diastolic heart failure
- Principal Investigator
  
  MASUYAMA Tohru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University

[Journal Article] Mitochondrial Responses to Sublethal Doxorubicin in H9c2 Cardiomyocytes: The Role of Phosphorylated CaMKII2024
- Author(s)
  Priyono Agung Kurniawan、Miake Junichiro、Sawano Tatsuya、Ichihara Yoshinori、Nagata Keiko、Okamura Akihiro、Tomomori Takuya、Takami Aiko、Notsu Tomomi、Yamamoto Kazuhiro、Imamura Takeshi
- Journal Title
  
  Yonago Acta Medica
  
  Volume: 67 Issue: 1 Pages: 41-51
- DOI
  10.33160/yam.2024.02.005
- ISSN
  0513-5710, 1346-8049
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20662, KAKENHI-PROJECT-23K07507, KAKENHI-PROJECT-23K10826
[Journal Article] Association of carnitine insufficiency with sarcopenia and dynapenia in patients with heart failure2023
- Author(s)
  Kinugasa Y, Sota T, Nakamura K, Hirai M, Kato M, Yamamoto K.
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 23 Issue: 7 Pages: 524-530
- DOI
  10.1111/ggi.14621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07507
[Journal Article] Simple Score to Predict Treatment Response to Low-Dose Tolvaptan in Patients with Heart Failure2022
- Author(s)
  Takami A, Kinugasa Y, Kamitani H, Nakamura K, Hirai M, Yanagihara K, Matsubara K, Kato M, Yamamoto K.
- Journal Title
  
  Int. Heart J.
  
  Volume: 63 Issue: 2 Pages: 247-254
- DOI
  10.1536/ihj.21-558
- NAID
  130008161343
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2022-03-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08582
[Journal Article] Impact of body mass index and ablation procedures on atrial fibrillation recurrence in Japanese patients2022
- Author(s)
  Takami A, Miake J, Kato M, Ogura K, Okamura A, Tomomoti T, Tsujimoto D, Kawatani S, Kato M, Yamamoto K.
- Journal Title
  
  J Asian Pacific Society Cardiol
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08582
[Journal Article] HFpEFの理解はいまどこまで進んでいるか？2022
- Author(s)
  山本　一博
- Journal Title
  
  Heart View
  
  Volume: 26 Pages: 38-43
- Data Source
  KAKENHI-PROJECT-19K08582
[Journal Article] Differences in needs for community collaboration for heart failure between medical and nursing care staff.2021
- Author(s)
  Kinugasa Y, Fukuki M, Hirota Y, Ishiga N, Kato M, Mizuta E, Mura E, Nozaka Y, Omodani H, Tanaka H, Tanaka Y, Watanabe I, Yamamoto K, Adachi T.
- Journal Title
  
  Heart Vessels.
  
  Volume: (online ahead of print) Issue: 6 Pages: 969-975
- DOI
  10.1007/s00380-021-01988-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08403
[Journal Article] Trimethylamine N-oxide and Outcomes in Patients Hospitalized with Acute Heart Failure and Preserved Ejection Fraction.2021
- Author(s)
  Kinugasa Y, Nakamura K, Kamitani H, Hirai M, Yanagihara K, Kato M, Yamamoto K.
- Journal Title
  
  ESC Heart Fail
  
  Volume: in press Issue: 3 Pages: 2103-2110
- DOI
  10.1002/ehf2.13290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08582
[Journal Article] Home-based inspiratory muscle training in patients with heart failure and preserved ejection fraction-a preliminary study-2020
- Author(s)
  Kinugasa Y, Sota T, Ishiga N, Nakamura K, Kamitani H, Hirai M, Yanagihara K, Kato M, Yamamoto K.
- Journal Title
  
  J Card Fail
  
  Volume: 26 Issue: 11 Pages: 1022-1023
- DOI
  10.1016/j.cardfail.2020.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08582
[Journal Article] L-carnitine supplementation in heart failure patients with preserved ejection fraction; a pilot study.2020
- Author(s)
  Kinugasa Y, Sota T, Ishiga N, Nakamura K, Kamitani H, Hirai M, Yanagihara K, Kato M, Yamamoto K.
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 20 Issue: 12 Pages: 1244-1245
- DOI
  10.1111/ggi.14060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08582
[Journal Article] Ultrasonographic assessment of organs other than the heart in patients with heart failure.2019
- Author(s)
  Yamamoto K, Kinugasa Y, Sugihara S, Mukai-Yatagai N, Kato M.
- Journal Title
  
  J Med Ultrasonics
  
  Volume: 46 Issue: 4 Pages: 389-397
- DOI
  10.1007/s10396-019-00953-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08582
[Journal Article] Dynapenia and diaphragm muscle dysfunction in patients with heart failure2018
- Author(s)
  Kinugasa Y, Miyagi M, Sota T, Yamada K, Ishisugi T, Hirai M, Yanagihara K, Haruki N, Matsubara K, Kato M, Yamamoto K
- Journal Title
  
  Eur J Prev Cardiol
  
  Volume: 25 Issue: 16 Pages: 1785-1786
- DOI
  10.1177/2047487318793212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09435
[Journal Article] Sex differences in surrogate decision-maker preferences for life-sustaining treatments of Japanese patients with heart failure2018
- Author(s)
  Nakamura K, Kinugasa Y, Sugihara S, Hirai M, Yanagihara K, Haruki N, Matsubara K, Kato M, Yamamoto K
- Journal Title
  
  ESC Heart Fail
  
  Volume: 5 Issue: 6 Pages: 1165-1172
- DOI
  10.1002/ehf2.12352
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09435
[Journal Article] Diaphragm muscle dysfunction in patients with heart failure2018
- Author(s)
  Miyagi M, Kinugasa Y, Sota T, Yamada K, Ishisugi T, Hirai M, Yanagihara K, Haruki N, Matsubara K, Kato M, Yamamoto K
- Journal Title
  
  J Card Fail
  
  Volume: 24 Issue: 4 Pages: 209-216
- DOI
  10.1016/j.cardfail.2017.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09435
[Journal Article] Monitoring Changes in Ejection Fraction in Patients With Heart Failure and Mid-Range Ejection Fraction2018
- Author(s)
  Kato M, Yamamoto K
- Journal Title
  
  Circ J
  
  Volume: 82 Issue: 8 Pages: 1991-1993
- DOI
  10.1253/circj.CJ-18-0663
- NAID
  130007419324
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2018-07-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09435
[Journal Article] The challenge of frailty and sarcopenia in heart failure with preserved ejection fraction.2017
- Author(s)
  Kinugasa Y, Yamamoto K.
- Journal Title
  
  Heart.
  
  Volume: 3 Issue: 3 Pages: 184-189
- DOI
  10.1136/heartjnl-2016-309995
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350566, KAKENHI-PROJECT-16K09435
[Journal Article] Pharmacological treatment of heart failure with preserved ejection fraction.2017
- Author(s)
  Yamamoto K
- Journal Title
  
  Yonago Acta Med
  
  Volume: 60 Pages: 71-76
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09435
[Journal Article] Carnitine insufficiency is associated with adverse outcomes in patients with heart failure with preserved ejection fraction.2016
- Author(s)
  Kinugasa Y, Sugihara S, Yamada K, Miyagi M, Matsubara K, Kato M, Yamamoto K.
- Journal Title
  
  J Aging Res Clin Practice
  
  Volume: ５ Pages: 187-193
- DOI
  10.14283/jarcp.2016.116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09435
[Journal Article] Child ego state is associated with high prevalence of repeated hospitalizations in patients with heart failure.2016
- Author(s)
  Yanagihara K, Kinugasa Y, Shirota K, Inoue Y, Ishii H, Tsunoda F, Iwata M, Sugihara S, Takeda S, Hirai M, Mimura A, Kato M, Yamamoto K
- Journal Title
  
  ESC Heart Fail
  
  Volume: ３ Issue: 1 Pages: 18-25
- DOI
  10.1002/ehf2.12060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] Inspiratory muscle weakness is associated with exercise intolerance in patients with heart failure with preserved ejection fraction: A preliminary study2016
- Author(s)
  山田健作
- Journal Title
  
  J Card Fail
  
  Volume: 22 Issue: 1 Pages: 38-47
- DOI
  10.1016/j.cardfail.2015.10.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350566, KAKENHI-PROJECT-25461058
[Journal Article] Beta–blocker Therapy in Heart Failure with Preserved Ejection Fraction: Importance of Dose and Duration2015
- Author(s)
  Yamamoto K
- Journal Title
  
  Journal of Cardiology
  
  Volume: 79 Issue: 3 Pages: 189-194
- DOI
  10.1016/j.jjcc.2015.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] Risk Factors for Progression of Degenerative Aortic Valve Disease in the Japanese　– The Japanese Aortic Stenosis Study (JASS) Prospective Analysis –2015
- Author(s)
  Yamamoto K, Yamamoto H, Takeuchi M, Kisanuki A, Akasaka T, Ohte N, Hirano Y, Yoshida K, Nakatani S, Takeda Y, Sozu T, Masuyama T.
- Journal Title
  
  Circ J
  
  Volume: 79 Issue: 9 Pages: 2050-2057
- DOI
  10.1253/circj.CJ-15-0499
- NAID
  130005095298
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461111, KAKENHI-PROJECT-25461058
[Journal Article] A double-blind placebo-controlled study of the effects of olprinone, a specific phosphodiesterase-III inhibitor, for preventing postoperative atrial fibrillation in patients undergoing pulmonary resection for lung cancer2015
- Author(s)
  Nojiri T, Yamamoto K, Maeda H, Takeuchi Y, Ose N, Susaki Y, Inoue M, Okumura M
- Journal Title
  
  Chest
  
  Volume: １４８ Issue: 5 Pages: 1285-1292
- DOI
  10.1378/chest.15-0852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] Depletion of Uric Acid Due to SLC22A12 (URAT1) Loss-of-Function Mutation Causes Endothelial Dysfunction in Hypouricemia2015
- Author(s)
  Sugihara S, Hisatome I, Kuwabara M, Niwa K, Maharani N, Kato M, Ogino K, Hamada T, Ninomiya H, Higashi Y, Ichida K, Yamamoto K
- Journal Title
  
  Circ J
  
  Volume: 79 Issue: 5 Pages: 1125-1132
- DOI
  10.1253/circj.CJ-14-1267
- NAID
  130005066259
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461057, KAKENHI-PROJECT-25461058, KAKENHI-PROJECT-25670762
[Journal Article] Commonly Encountered in Clinical Practice but Only a Minority in Clinical Trials2015
- Author(s)
  Yamamoto K
- Journal Title
  
  Int. Heart J.
  
  Volume: 56 Issue: 2 Pages: 135-136
- DOI
  10.1536/ihj.15-020
- NAID
  130004941302
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] “The Third Man” in Heart Failure　– Heart Failure With Reduce Ejection Fraction Evolved From Heart Failure With Preserved Ejection Fraction –2015
- Author(s)
  Yamamoto K
- Journal Title
  
  Circ J
  
  Volume: 79 Issue: 10 Pages: 2108-2109
- DOI
  10.1253/circj.CJ-15-0857
- NAID
  130005099871
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] Clinical Scenario 1 Is Associated With Winter Onset of Acute Heart Failure2014
- Author(s)
  Hirai M, Kato M, Kinugasa Y, Sugihara S, Yanagihara K, Yamada K, Watanabe T, Yamamoto K.
- Journal Title
  
  Circ J
  
  Volume: 79 Issue: 1 Pages: 129-135
- DOI
  10.1253/circj.CJ-14-0710
- NAID
  130004704030
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] Glucocorticoids induce cardiac fibrosis via mineralocorticoid receptor in oxidative stress: contribution of elongation factor eleven-nineteen lysine-rich leukemia (ELL)2014
- Author(s)
  Omori Y, Mano T, Ohtani T, Sakata Y, Takeda Y, Tamaki S, Tsukamoto Y, Miwa T, Yamamoto K, Komuro I.
- Journal Title
  
  Yonago Acta medica
  
  Volume: 57 Pages: 109-116
- NAID
  120005482531
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] Relation of risk factors with response to carvedilol in heart failure with preserved ejection fraction - A report from the Japanese Diastolic Heart Failure Study (J-DHF)-2014
- Author(s)
  Yamamoto K, Origasa H, Suzuki Y, Takahashi T, Shinozaki T, Watanabe T, Sakata Y, Izumi C, Taira K, Hori M.
- Journal Title
  
  J Cardiol
  
  Volume: 63 Issue: 6 Pages: 424-431
- DOI
  10.1016/j.jjcc.2013.10.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] Endovascular Aortic Repair Increases Vascular Stiffness and Alters Cardiac Structure and Function2014
- Author(s)
  Takeda Y, Sakata Y, Ohtani T, Tamaki S, Omori Y, Tsukamoto Y, Aizawa Y, Shimamura K, Shirakawa Y, Kuratani T, Sawa Y, Yamamoto K, Mano T, Komuro I.
- Journal Title
  
  Circ J
  
  Volume: 78 Issue: 2 Pages: 322-328
- DOI
  10.1253/circj.CJ-13-0877
- NAID
  130003382224
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] Multidisciplinary intensive education in the hospital improves outcomes for hospitalized heart failure patients in a Japanese rural setting2014
- Author(s)
  Kinugasa Y, Kato M, Sugihara S, Yanagihara K, Yamada K, Hirai M, Yamamoto K.
- Journal Title
  
  BMC Health Serv Res
  
  Volume: 14 Issue: 1 Pages: 315-315
- DOI
  10.1186/1472-6963-14-351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction.2013
- Author(s)
  Tamaki S, Komuro I (19人中19番目）
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 7 Pages: e68893-e68893
- DOI
  10.1371/journal.pone.0068893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229010, KAKENHI-PLANNED-23106003, KAKENHI-PROJECT-23591042
[Journal Article] Discharge use of carvedilol is associated with higher survival in Japanese elderly patients with heart failure regardless of left ventricular ejection fraction2013
- Author(s)
  Yanagihara K, Kinugasa Y, Sugihara S, Hirai M, Yamada K, Ishida K, Kato M, Yamamoto K
- Journal Title
  
  J Cardiovasc Pharmacol
  
  Volume: 62 Issue: 5 Pages: 485-90
- DOI
  10.1097/fjc.0000000000000006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] The main target for inhibiting mineralocorticoid receptor-mediated signaling pathway in cardiovascular diseases2013
- Author(s)
  Yamamoto K
- Journal Title
  
  Hypertens Res
  
  Volume: 36 Issue: 7 Pages: 580-2
- DOI
  10.1038/hr.2013.42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461058
[Journal Article] L-Carnitine prevents the development of ventricular fibrosis and heart failure with preserved ejection fraction in hypertensive heart disease2012
- Author(s)
  Omori Y, Ohtani T, Sakata Y, Mano T, Takeda Y, Tamaki S, Tsukamoto Y, Kamimura D, Aizawa Y, Miwa T, Komuro I, Soga T, Yamamoto K.
- Journal Title
  
  J Hypertens
  
  Volume: 30 Issue: 9 Pages: 1834-44
- DOI
  10.1097/hjh.0b013e3283569c5a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591042
[Journal Article] Ca2+ entry mode of Na+/Ca2+ exchanger as a new therapeutic target for heart failure with preserved ejection fraction2011
- Author(s)
  Kamimura D, Ohtani T, Sakata Y, Mano T, Takeda Y, Tamaki S, Omori Y, Tsukamoto Y, Furutani K, Komiyama Y, Yoshika M, Takahashi H, Matsuda T, Baba A, Umemura S, Miwa T, Komuro I, Yamamoto K
- Journal Title
  
  European Heart Journal
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590893
[Journal Article] Ca2+ Entry Mode of Na+/ Ca2+ Exchanger as A New Therapeutic Target for Heart Failure with Preserved Ejection Fraction2011
- Author(s)
  Kamimura D, Ohtani T, Sakata Y, Mano T, Tkaeda Y, Tamaki S, Omori Y, Tshkamoto Y, Furutani K, Komiyama Y, Yoshika M, Takahashi H, Matsuda T, Baba A, Umemura S, Miwa T, Komuro I, Yamamoto K.
- Journal Title
  
  Eur Heart J
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590893
[Journal Article] Heart Failure with Preserved Ejection Fraction2009
- Author(s)
  Yamamoto K, Sakata Y, et al
- Journal Title
  
  Circ J 73
  
  Pages: 404-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590893
[Journal Article] Beneficial effects of bisoprolol on the survival of hypertensive diastolic heart failure model rats2008
- Author(s)
  Nishio M, Sakata Y, Mano T, Ohtani T, Takeda Y, Miwa T, Hori M, Masuyama T, Kondo T, Yamamoto K
- Journal Title
  
  Eur J Heart Fail
  
  Pages: 446-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500420
[Journal Article] Difference of Clinical Characteristics between Hypertensive Patients with and without Diastolic Heart Failure : Role of Diastolic Dysfunction and Renal Insufficiency2008
- Author(s)
  Nishio M, Sakata Y, Mano T, Ohtani T, Takeda Y, Hori M, Yamamoto K
- Journal Title
  
  Hypertens Res 31
  
  Pages: 1865-72
- NAID
  10024827442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500420
[Journal Article] Noninvasive Assessment of Diastolic Function in Subjects with Preserved Ejection Fraction : Usefulness of Color Kinetic Imaging2008
- Author(s)
  Takeda Y, Sakata Y, Mano T, Nishio M, Ohtani T, Hori M, Masuyama T, Yamamoto K
- Journal Title
  
  J Card Fail 7
  
  Pages: 569-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500420
[Journal Article] Elevated Cardiac Tissue Level of Aldosterone and Mineralocorticoid Receptor in Diastolic Heart Failure: Beneficial Effects of Mineralocorticoid Receator Blocker.2007
- Author(s)
  Ohtani T, Ohta M, Yamamoto K, Mano T, Sakata Y, et. al.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500420
[Journal Article] Therapeutic effects of angiotensin II type 1 receptor blocker at an advanced stage of hypertensive diastolic heart failure2007
- Author(s)
  Nishio M, Sakata Y, Mano T, Yoshida J, Ohtani T, Takeda Y, Miwa T, Masuyama T, Yamamoto K, Hori M
- Journal Title
  
  J Hypertens 25
  
  Pages: 455-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500420
[Journal Article] Elevated Cardiac Tissue Level of Aldosterone andMineralocorticoid Receptor in Diastolic Heart Failure : Beneficial Effects of Mineralocorticoid Receptor Blocker2007
- Author(s)
  Ohtani T, Ohta M, Yamamoto K, Mano T, Sakata Y, Nishio M, Takeda Y, Yoshida J, Miwa T, Okamoto M, Masuyama T, Nonaka Y, Hori M
- Journal Title
  
  Am J Physiol Heart Circ Physiol 292
  
  Pages: 946-956
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500420
[Journal Article] ACE inhibitor and angiotensin II type I receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure2005
- Author(s)
  Kazuhiro Yamamoto
- Journal Title
  
  J Hypertens 23・2
  
  Pages: 393-400
- Data Source
  KAKENHI-PROJECT-15300184
[Journal Article] ACE inhibitor and angiotensin II type 1 receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure2005
- Author(s)
  Kazuhiro Yamamoto
- Journal Title
  
  J Hypertens 23
  
  Pages: 393-400
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300184
[Journal Article] ACE Inhibitor and angiotensin II type I receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure2005
- Author(s)
  Kazuhiro Yamamoto
- Journal Title
  
  Journal of Hypertension 23(2)
  
  Pages: 393-400
- Data Source
  KAKENHI-PROJECT-15590742
[Journal Article] ACE Inhibitor and angiotensin II type 1 receptor Mocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure.2005
- Author(s)
  Kazuhiro Yamamoto
- Journal Title
  
  Journal of Hypertension 23(2)
  
  Pages: 393-400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590742
[Journal Article] ACE Inhibitor and angiotensin II type 1 receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure2005
- Author(s)
  Kazuhiro Yamamoto
- Journal Title
  
  Journal of Hypertension 23(2)
  
  Pages: 393-400
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590742
[Journal Article] ACE Inhibitor and angiotensin II type 1 receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure.2005
- Author(s)
  Kazuhiro Yamamoto
- Journal Title
  
  Journal of Hypertension 23(2)
  
  Pages: 393-400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300184
[Journal Article] N-Methylethanolamine attenuates cardiac fibrosis and improves diastolic function : inhibition of phospholipase D as a possible mechanism.2004
- Author(s)
  Kazuhiro Yamamoto
- Journal Title
  
  European Heart Journal 25(14)
  
  Pages: 1221-1229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590742
[Journal Article] N-Methylethanolamine attenuates cardiac fibrosis and improves diastolic function : inhibition of phospholipase D as a possible mechanism2004
- Author(s)
  Kazuhiro Yamamoto
- Journal Title
  
  European Heart Journal 25(14)
  
  Pages: 1221-1229
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590742
[Journal Article] N-Methylethanolamine attenuates cardiac fibrosis and improves diastolic function : inhibition of phospholipase D as a possible mechanism2004
- Author(s)
  Kazuhiro Yamamoto
- Journal Title
  
  European Heart Journal 25(14)
  
  Pages: 1221-1229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300184
[Journal Article] N-methylethanolamine attenuates cardiac fibrosis and improves diastolic function : inhibition of phospholipase D as a possible mechanism.2004
- Author(s)
  Kazuhiro Yamamoto
- Journal Title
  
  Eur Heart J 25
  
  Pages: 1221-1229
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300184
[Journal Article] N-methylethanolamine attenuates cardiac fibrosis and improves diastolic function : inhibition of phospholipase D as a possible mechanism2004
- Author(s)
  Kazuhiro Yamamoto
- Journal Title
  
  Eur Heart J 25・14
  
  Pages: 1221-1229
- Data Source
  KAKENHI-PROJECT-15300184
[Presentation] Managing Frailty in HFPEF.2023
- Author(s)
  Yamamoto K.
- Organizer
  European Society of Cardiology Congress 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07507
[Presentation] HFpEFにおける骨格筋の水分バランスと握力低下との関連2023
- Author(s)
  中村研介、平井雅之、衣笠良治、山本一博
- Organizer
  第７１回日本心臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07507
[Presentation] Diastolic function in patients with frailty and dynapenia2021
- Author(s)
  山本　一博
- Organizer
  Echo Seoul & Cardiac Imaging 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08582
[Presentation] Diagnostic components and classification.2020
- Author(s)
  Yamamoto K
- Organizer
  HFA Discoveries operated by Heart Failure Association of European Society of Cardiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08582
[Presentation] The ego states interfere with self-care behavior change in patients with heart failure2019
- Author(s)
  柳原清孝、衣笠良治、國見哲郎、春木伸彦、平井雅之、加藤雅彦、山本一博
- Organizer
  第83回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09435
[Presentation] HFpEF-associated changes related to microcirculation2019
- Author(s)
  Yamamoto K
- Organizer
  Heart Failure Seoul 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08582
[Presentation] 心不全における栄養管理の意義2019
- Author(s)
  衣笠良治、中村研介、神谷裕子、平井雅之、柳原清孝、加藤雅彦、山本一博
- Organizer
  第23回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08582
[Presentation] 左室駆出率の低下した心不全2019
- Author(s)
  山本一博
- Organizer
  第59回日本呼吸器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08582
[Presentation] Ultrasonographic Assessment of Non-Cardiac Organs in the Evaluation of the Severity of Heart Failure2019
- Author(s)
  Yamamoto K
- Organizer
  American Society of Echocardiography 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08582
[Presentation] 心不全の考え方　～病態からガイドラインまで～2019
- Author(s)
  山本一博
- Organizer
  第25回日本心臓リハビリテーション学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08582
[Presentation] 急性冠症候群と心不全患者の性格（エゴ）評価2018
- Author(s)
  國見哲郎、柳原清孝、衣笠良治、春木伸彦、平井雅之、万場みどり、加藤雅彦、山本一博
- Organizer
  第22回日本心不全学会
- Data Source
  KAKENHI-PROJECT-16K09435
[Presentation] 急性冠症候群と心不全患者の性格（エゴ）評価2017
- Author(s)
  國見哲郎、柳原清孝、衣笠良治、春木伸彦、平井雅之、万場みどり、加藤雅彦、山本一博
- Organizer
  第21回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09435
[Presentation] 心筋梗塞患者における性格タイプ別の受療行動の特徴2017
- Author(s)
  石賀奈津子、曽田武史、中山奈都子、衣笠良治、吉持智恵、加藤雅彦、山本一博
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  ANAクラウンプラザホテル金沢（石川県金沢市）
- Year and Date
  2017-03-18
- Data Source
  KAKENHI-PROJECT-16K09435
[Presentation] Change in the Left Kidney Volume is Associated with Worsening Renal Function in Patients with Acute Decompensated Heart Failure2016
- Author(s)
  Sugihara S, Kinugasa Y, Yamada K, Katoh M, Yamamoto K
- Organizer
  第80回日本循環器学会学術集会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] The Assessment of Impaired Sleep Quality in Patients with Chronic Heart Failure2016
- Author(s)
  Kato M, Yamada K, Fujiyama M, Matsuda E, Sugihara S, Matsubara K, Kinugasa Y、Yamamoto K
- Organizer
  第80回日本循環器学会学術集会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] Child Ego State is Associated with High Prevalence of Repeated Hospitalizations in Patients with Heart Failure2016
- Author(s)
  Yanagihara K, Kinugasa Y, Shirota K, Inoue Y, Ishii H, Tsunoda F, Sugihara S, Hirai M, Mimura A, Katoh M, yamamoto K
- Organizer
  第80回日本循環器学会学術集会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-03-20
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] Characteristics of heart failure with preserved ejection fraction2015
- Author(s)
  Yamamoto K
- Organizer
  第19回日本心不全学会学術集会
- Place of Presentation
  グランフロント大阪
- Year and Date
  2015-10-24
- Invited
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] Non-cardiac Factors to Determine the Pathophysiology of Elder HFpEF2015
- Author(s)
  Yamamoto K.
- Organizer
  第７９回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2015-04-26
- Invited
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] 拡張不全の病態と治療―最新の治験―2015
- Author(s)
  山本　一博
- Organizer
  第63回日本心臓病学会学術集会
- Place of Presentation
  パシフィコ横浜国際会議場
- Year and Date
  2015-09-19
- Invited
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] Medical treatment in Japan2015
- Author(s)
  Yamamoto K.
- Organizer
  第７９回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2015-04-25
- Invited
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] L-carnitine Insufficiency is Associated with Post-discharge Outcomes in Patients Hospitalized with Acute Decompensated Heart Failure2015
- Author(s)
  Kinugasa Y, Sugihara S, Yamada K, Katoh M, Yamamoto K
- Organizer
  第７９回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] What exactly is HFpEF and How Do We Diagnose It?2015
- Author(s)
  Yamamoto K
- Organizer
  19th Annual Scientific Meeting of Heart Failure Society of America
- Place of Presentation
  Washington DC, USA
- Year and Date
  2015-09-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] Prevalence and Characteristics of L-carnitine Insufficiency in Patients with Decompensated Heart Failure: Who may be Candidate for L-carnitine Supplementation?2014
- Author(s)
  Kinugasa Y, Katoh M, Yamada K, Hirai M, Yamamoto K
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム、東京、日本
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] HFpEFの病態2014
- Author(s)
  山本　一博
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  横浜国際会議場（横浜市）
- Year and Date
  2014-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] HFpEFへの新規アプローチを考える2014
- Author(s)
  山本　一博
- Organizer
  第14回日本抗加齢医学会総会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2014-06-08
- Invited
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] Noninvasive assessment of ventricular distensibility and its clinical utility2014
- Author(s)
  Yamamoto K
- Organizer
  22th Korean Society of Echocardiography Workshop
- Place of Presentation
  Kyunghee University Hospital, Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] HFpEF as a cause of ADHF; Treatment2013
- Author(s)
  Yamamoto K
- Organizer
  Kinshukai the 1st Cardiovascular Ingternational Symposium
- Place of Presentation
  New Otani Hotel, Osaka, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-25461058
[Presentation] Left atrial dilatation as a predictive factor of beneficial response to carvedilol in patients with HFPEF2013
- Author(s)
  Yamamoto K, Origasa H, Hori M
- Organizer
  ESC Congress 2013
- Place of Presentation
  Amsterdam RAI, Amsterdam, The Netherland
- Data Source
  KAKENHI-PROJECT-25461058

1. KINUGASA Yoshiharu (60598944)

# of Collaborated Projects: 8 results

# of Collaborated Products: 25 results
2. KATO Masahiko (40362884)

# of Collaborated Projects: 7 results

# of Collaborated Products: 23 results
3. MANO Toshiaki (90379165)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
4. 柳原清孝 (50788180)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
5. SAKATA Yasushi (00397671)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
6. MASUYAMA Tohru (70273670)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. MIWA Takeshi (20174229)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OTSU Kinya (20294051)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 三明淳一朗 (40372677)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. SUGIHARA Shinobu

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
11. HORAI Masayuki

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
12. HORI Masatsugu (20124779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TSUJINO Takeshi (90283887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKAO Shinji (80309450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SHIOZAKI Akira (40103345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NISHIDA Kazuhiko (90362681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Haruki Nobuhiko (70469394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 近藤寛也 (40294102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YAMADA Kensaku

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
20. WATANABE Tomomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. DOI Reiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 小室一成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamamoto Kazuhiro 山本 一博

YAMAMOTO Kazuhiro 山本 一博

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Co-Researchers

Exploratory research to elucidate the molecular mechanisms by which depression makes heart failure more severe and to reconstruct heart failure treatment strategies.Principal Investigator

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Investigation about nteraction among carnitine deficiency, dynapenia and diaphragm muscle dysfunction for the effective nutritional intervention in heart failurePrincipal Investigator

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investigation about relation between patient's ego and achievement of patient education in heart failure: in pursuit of efficient patient educationPrincipal Investigator

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Effects of L-carnitine on cardiac and skeletal muscle function in patients with heart failure and preserved ejection fractionPrincipal Investigator

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Gene expression profiling in hypertrophied heart as the determinant of phenotype of heart failurePrincipal Investigator

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Yamamoto Kazuhiro 山本一博

YAMAMOTO Kazuhiro 山本一博