AMANO Mutsuki 天野睦紀

Researcher Number	90304170
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2022: 名古屋大学, 医学系研究科, 准教授 2011 – 2016: 名古屋大学, 医学(系)研究科(研究院), 准教授 2014: 名古屋大学, 大学院医学系研究科, 准教授 2012: 名古屋大学, 大学院・医学系研究科, 准教授 2010 – 2011: Nagoya University, 医学系研究科, 准教授 … More 2007 – 2009: Nagoya University, Graduate School of Medicine, Associate Professor 2005 – 2006: 名古屋大学, 大学院医学系研究科, 講師 2002 – 2005: 名古屋大学, 大学院・医学系研究科, 講師 2003: Nagoya University, Graduate School of Medicine, Assistant Professor, 大学院・医学研究科, 講師 2001 – 2002: 名古屋大学, 大学院・医学研究科, 助手 1999 – 2000: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Pathological medical chemistry / Cell biology / Cell biology / General medical chemistry Except Principal Investigator Cell biology / Cardiovascular medicine / Hematology / General surgery / Biological Sciences … More / Basic Section 53020:Cardiology-related / Basic Section 50010:Tumor biology-related / Basic Section 54010:Hematology and medical oncology-related / Neurophysiology / General neuroscience / Complex systems / Surgical dentistry / Neuroscience in general / Cell biology / Neuroscience in general Less
Keywords	Principal Investigator Rho / シグナル伝達 / Rho-kinase / リン酸化 / 細胞骨格 / キナーゼ / プロテオーム / ミオシン / CRMP-2 / STEF … More / ARHGAP9 / PAR-3 / eNOS / Rac / 細胞内シグナル伝達 / 細胞遊走 / Rhoファミリー / 極性形成 / 形態形成 / MBS / Rho-キナーゼ / 細胞内情報伝達 / 基質 / プロテインキナーゼ / sienal transduction / SNP / プロテオミクス / 高血圧 / 精神疾患 / 冠攣縮 / 循環器 / 酵素 / 細胞接着 / 微小管 / 細胞極性 / endophllin / エンドサイトーシス / 蛋白質 / 癌 / 遺伝子 / 軸索 / 神経細胞 / NKA / Na^+K^+-ATPase / RNAi / veast two-hybrid / GEX-3 / GEX-2 / GEX3 / GEX2 / 神経発生 / 培養細胞 / 線虫 / 細胞質分裂 / 細胞運動 / 成長円錐 / LPA / アクチン / calponin … More Except Principal Investigator リン酸化 / CRMP-2 / Rho-kinase / IQGAP1 / Rho / キナーゼ / シグナル伝達 / 細胞極性 / Rho-キナーゼ / 心不全 / Rhoファミリー / eNOS / Rho-GEF / 軸索 / カドヘリン / Rac / 細胞間接着 / 神経科学 / エフェクター / Rho GTPase / フォルミン / 脂質メディエーター / RhoA / Rho-kinesis / Phosphorylation / IQGAP / Rho ファミリー / 脳・神経 / プロテオーム / 極性 / 遊走 / エンドサイトーシス / Numb / 微小管 / 細胞骨格 / 神経 / 樹状突起 / 成長円錐 / Cdc42 / 低分子量G蛋白質 / 心筋細胞 / 治療標的 / リン酸化蛋白質 / 骨肉腫幹細胞 / 乳がん / 脳腫瘍 / リン酸化シグナル / がん幹細胞 / 12-リポキシゲナーぜ / 血栓形成 / 血栓症 / ALOX / small GTPase / アラキドン酸 / 学習 / プロテオミクス解析 / 遺伝子発現 / シナプス可塑性 / 神経活動 / 学習・記憶 / 情動行動 / ニューロモジュレーター / リン酸化プロテオミクス解析 / 細胞内シグナル / 神経化学 / 発生・分化 / 遺伝学 / 進化 / AUTS2 / 遺伝子 / Auts2 / Ptf1a / 自閉症スペクトラム障害 / 性分化 / 脳 / 個性 / アラキドン酸リポキシゲナーゼ / 血管老化 / リポキシゲナーゼ / 細胞内輸送 / midkine / autologous vein graft / inhibition of intimal hyperplasia / statin / ミッドカイン / 自家静脈グラフト / 内膜肥厚抑制 / スタチン / contraction / simulation / signal transduction / Rho family / migration / axon / polarily / KIF3A / PAR-3 / APC / GSK-3β / PI3-kinase / PAR複合体 / 神経細胞 / 運命決定 / アクチン / チューブリン / WAVE1 / Sra-1 / コンピューターシミュレーション / Kinesin / Disc1 / ミオシン / Par-3 / 収縮 / シミュレーション / 細胞遊走 / 神経軸索 / METASTASIS / ORAL CANCER / 転移 / 口腔癌 / Cell Polarity / Dendrite / Axon / Growth Cone / cell adhesion / cell migration / cadherin / Small GTPases / 細胞質分裂 / 細胞接着 / 細胞運動 / 低分子量GTPase / 低分子量RhoA / 低分子量Rho / 質量分析 / 細胞内情報伝達 / フィロポディア / 造血 / 分化 / ノックアウト / リンパ球 / knock out / marzinal zone / filopodia / RhoF / 記憶障害 / 情動障害 / 相互作用 / 行動解析 / 遺伝子改変マウス / レット症候群 / 海馬 / プロテオーム解析 / ノックアウトマウス / シナプス / てんかん / 発達障害 / 小胞輸送 / 内膜肥厚 / 軸索伸長 / 極性形成 / CLIP-170 / β-catenin / AF-6 / Fam / 脱ユビキチン化酵素 / プロテアソーム / ユビキチン Less

Signaling of protein phosphorylation in cancer stem cells for therapeutic target molecules
- Principal Investigator
  
  Watanabe Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Fujita Health University
The role of GPCR in cardiac diastolic dysfunction
- Principal Investigator
  
  Takefuji Mikito
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Nagoya University
Activation mechanism of 12-Lypoxigenase in thrombus formation
- Principal Investigator
  
  Katsumi Akira
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Center for Geriatrics and Gerontology
Analysis of substrate recognition and regulatory mechanisms for protein kinases.Principal Investigator
- Principal Investigator
  
  Amano Mutsuki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
The role of protein kinase N in cardiomyocyte
- Principal Investigator
  
  TAKEFUJI MIKITO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Nagoya University
Study on regulatory mechanism of neural activity and emotional behavior by intracellular signals
- Principal Investigator
  
  Kaibuchi Kozo
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Nagoya University
Analysis of genes that affect individuality
- Principal Investigator
  
  Hoshino MIkio
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  National Center of Neurology and Psychiatry
The role of cellular localization of ALOX proteins in vascular aging
- Principal Investigator
  
  KATSUMI Akira
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  National Center for Geriatrics and Gerontology
  Hamamatsu University School of Medicine
Novel molecular mechanism of Rho related kinase modifying heart failure condition and development of therapeutic drug
- Principal Investigator
  
  TAKEFUJI MIKITO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Nagoya University
Elucidation of phosphorylation signal regulating the cell polarity
- Principal Investigator
  
  Kaibuchi Kozo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
RhoF promotes murine marginal zone B cell development
- Principal Investigator
  
  KATSUMI Akira
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Hamamatsu University School of Medicine
Multidimensional analyses of the CDKL5, a causative gene for neurodevelopment disorders, by proteomic and LOF approaches
- Principal Investigator
  
  Tanaka Teruyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  The University of Tokyo
Involvement of small GTPase Rho family signaling pathways in diseases.Principal Investigator
- Principal Investigator
  
  AMANO Mutsuki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University
細胞増殖・分化に関わる蛋白質リン酸化酵素の新規基質スクリーニング法の開発Principal Investigator
- Principal Investigator
  
  天野睦紀
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
MOLECULAR MECHANISMS UNDERLYING CELL POLARIZATION IN MIGRATING CELLS AND NEURONS
- Principal Investigator
  
  KAIBUCHI Kozo
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
Analysis of disease-related genes involved in Rho family small GTPase signalingPrincipal Investigator
- Principal Investigator
  
  AMANO Mutsuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University
Analysis of disease susceptibility genes on Rho family signaling moleculesPrincipal Investigator
- Principal Investigator
  
  AMANO Mutsuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Rhoキナーゼの新しい展開
- Principal Investigator
  
  KOMORI Kimihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Nagoya University
Effects of statin on vascular diseases-inhibitory mechanism on intimal hyperplasia
- Principal Investigator
  
  KOBAYASHI Masayoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nagoya University
微小管ダイナミクスと細胞極性・遊走の制御機構Principal Investigator
- Principal Investigator
  
  天野睦紀
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
細胞間接着及び細胞遊走制御系の解析Principal Investigator
- Principal Investigator
  
  天野睦紀
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
細胞間接着制御系の網羅的解析Principal Investigator
- Principal Investigator
  
  天野睦紀
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
細胞の極性・遊走を制御する分子機構の解明
- Principal Investigator
  
  貝淵弘三
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
Molecular mechanism underlying cell polarity and cell migration
- Principal Investigator
  
  KAIBUCHI Kozo
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Nagoya University
細胞間接着制御系の網羅的解析
- Principal Investigator
  
  深田正紀
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Isolation of cell lines with high potentials for lymphatic metastasis from active Rho-Kinase-transfected oral carcinoma and clarification of their machanism of metastasis
- Principal Investigator
  
  KOMORI Takahide
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kobe University
形態を制御する細胞内骨格制御系の網羅的解析Principal Investigator
- Principal Investigator
  
  天野睦紀
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Rhoファミリー及びそのエフェクター分子を介する細胞骨格分子の制御機構Principal Investigator
- Principal Investigator
  
  天野睦紀
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
低分子量G蛋白質とその標的蛋白質による血管構築の分子機構
- Principal Investigator
  
  貝淵弘三
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
CRMP-2による神経軸索・樹状突起の運命決定機構の解明
- Principal Investigator
  
  稲垣直之
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
形態を制御する細胞内骨格制御系の網羅的解析Principal Investigator
- Principal Investigator
  
  天野睦紀
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
蛋白質分解による細胞間接着の制御メカニズムの解析
- Principal Investigator
  
  KAIBUCHI Kozo
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nara Institute of Science and Technology
低分子量G蛋白質とその標的蛋白質による血管構築の分子機構
- Principal Investigator
  
  貝淵弘三
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nara Institute of Science and Technology
低分子量GTP結合蛋白質Rhoを介する細胞骨格の制御機構Principal Investigator
- Principal Investigator
  
  天野睦紀
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Nara Institute of Science and Technology
Regulation of Cytoskeletons and Cell Adhesions by the Rho Family GTPases.
- Principal Investigator
  
  KAIBUCHI Kozo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
  Nara Institute of Science and Technology
ANALYSIS OF MOLECULAR MECHANISMS FOR NEURAL NETWOEK FORMATION BY RHO FAMILY
- Principal Investigator
  
  NAOYUKI Inagaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  NARA INSTITUTE OF SCIENCE AND TECHNOLOGY

[Journal Article] Dynamic subcellular localization and transcription activity of the SRF cofactor MKL2 in the striatum are regulated by MAPK2021
- Author(s)
  Ariza Anthony、Funahashi Yasuhiro、Kozawa Sachi、Omar Faruk Md.、Nagai Taku、Amano Mutsuki、Kaibuchi Kozo
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: - Issue: 6 Pages: 1774-1788
- DOI
  10.1111/jnc.15303
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05209, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-17K07383, KAKENHI-PROJECT-18K14849
[Journal Article] Dopamine Receptor Dop1R2 Stabilizes Appetitive Olfactory Memory through the Raf/MAPK Pathway in Drosophila2020
- Author(s)
  Sun Huan、Nishioka Tomoki、Hiramatsu Shun、Kondo Shu、Amano Mutsuki、Kaibuchi Kozo、Ichinose Toshiharu、Tanimoto Hiromu
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 40 Issue: 14 Pages: 2935-2942
- DOI
  10.1523/jneurosci.1572-19.2020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16265, KAKENHI-PROJECT-17H01378, KAKENHI-PROJECT-20H03246, KAKENHI-PROJECT-17K07383
[Journal Article] Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility.2020
- Author(s)
  Hayase Y, Amano S, Hashizume K, Tominaga T, Miyamoto H, Kanno Y, Ueno-Inoue Y, Inoue T, Yamada M, Ogata S, Balan S, Hayashi K, Miura Y, Tokudome K, Ohno Y, Nishijo T, Momiyama T, Yanagawa Y, Takizawa A, Mashimo T, Serikawa T, Sekine A, Nakagawa E, Takeshita E, Yoshikawa T, Waga C, Inoue K, Goto YI, Nabeshima Y, et al.
- Journal Title
  
  Acta Neuropathol Commun.
  
  Volume: 8 Issue: 1 Pages: 206-206
- DOI
  10.1186/s40478-020-01082-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-20K06667, KAKENHI-PROJECT-20K06886, KAKENHI-PROJECT-18KK0307, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-17K07063, KAKENHI-PROJECT-17K07126, KAKENHI-PROJECT-18K07577, KAKENHI-PLANNED-16H06528, KAKENHI-PLANNED-16H06532, KAKENHI-PROJECT-18H02538
[Journal Article] ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk2020
- Author(s)
  Mariko Sekiguchi, Akiko Kodama,... Emiko Shishido,... Daisuke Mori, Norio Ozaki
- Journal Title
  
  Translational psychiatry
  
  Volume: 10 Issue: 1 Pages: 1-15
- DOI
  10.1038/s41398-020-00917-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08072, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20K07965, KAKENHI-PROJECT-20K21832, KAKENHI-PROJECT-18K14816, KAKENHI-PROJECT-20K16488, KAKENHI-PROJECT-20K16625, KAKENHI-PROJECT-19H05467, KAKENHI-PUBLICLY-19H05210, KAKENHI-PUBLICLY-20H04841, KAKENHI-PROJECT-18H04040, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-17K07383, KAKENHI-PROJECT-18K15512, KAKENHI-PROJECT-19K16111, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-18KT0022
[Journal Article] Protein kinases phosphorylate long disordered regions in intrinsically disordered proteins2019
- Author(s)
  Koike Ryotaro、Amano Mutsuki、Kaibuchi Kozo、Ota Motonori
- Journal Title
  
  Protein Science
  
  Volume: 29 Issue: 2 Pages: 564-571
- DOI
  10.1002/pro.3789
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12217, KAKENHI-PUBLICLY-19H05390, KAKENHI-PROJECT-18H03331, KAKENHI-PROJECT-17K07383
[Journal Article] Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of Its Interaction With Actin.2019
- Author(s)
  Sakaguchi T, Takefuji M, Wettschureck N, Hamaguchi T, Amano M, Kato K, Tsuda T, Eguchi S, Ishihama S, Mori Y, Yura Y, Yoshida T, Unno K, Okumura T, Ishii H, Shimizu Y, Bando YK, Ohashi K, Ouchi N, Enomoto A, Offermanns S, Kaibuchi K, Murohara T.
- Journal Title
  
  Circulation.
  
  Volume: 140 Issue: 21 Pages: 1737-1752
- DOI
  10.1161/circulationaha.119.041019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19541, KAKENHI-PROJECT-17H04175, KAKENHI-PROJECT-19H03651, KAKENHI-PROJECT-17K09571, KAKENHI-PROJECT-18H02805, KAKENHI-PROJECT-17K09573, KAKENHI-PROJECT-17K07383
[Journal Article] Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs2019
- Author(s)
  Nakamura Mari、Shiozawa Seiji、Tsuboi Daisuke、Amano Mutsuki、Watanabe Hirotaka、Maeda Sumihiro、Kimura Taeko、Yoshimatsu Sho、Kisa Fumihiko、Karch Celeste M.、Miyasaka Tomohiro、Takashima Akihiko、Sahara Naruhiko、Hisanaga Shin-ichi、Ikeuchi Takeshi、Kaibuchi Kozo、Okano Hideyuki
- Journal Title
  
  Stem Cell Reports
  
  Volume: 13 Issue: 4 Pages: 684-699
- DOI
  10.1016/j.stemcr.2019.08.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06472, KAKENHI-PROJECT-19K06896, KAKENHI-PUBLICLY-19H05437, KAKENHI-PROJECT-19J12871, KAKENHI-PROJECT-17K08668, KAKENHI-PROJECT-17K07383, KAKENHI-PLANNED-18H05414
[Journal Article] Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors2019
- Author(s)
  Funahashi Yasuhiro、Ariza Anthony、Emi Ryosuke、Xu Yifan、Shan Wei、Suzuki Ko、Kozawa Sachi、Ahammad Rijwan Uddin、Wu Mengya、Takano Tetsuya、Yura Yoshimitsu、Kuroda Keisuke、Nagai Taku、Amano Mutsuki、Yamada Kiyofumi、Kaibuchi Kozo
- Journal Title
  
  Cell Reports
  
  Volume: 29 Issue: 10 Pages: 3235-3252.e9
- DOI
  10.1016/j.celrep.2019.10.116
- NAID
  130007812598
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14816, KAKENHI-PROJECT-18K14849, KAKENHI-PUBLICLY-19H05209, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17J09461, KAKENHI-PROJECT-17K07383
[Journal Article] In Vivo Identification of Protein Kinase Substrates by Kinase-Oriented Substrate Screening (KIOSS)2019
- Author(s)
  Nishioka Tomoki、Amano Mutsuki、Funahashi Yasuhiro、Tsuboi Daisuke、Yamahashi Yukie、Kaibuchi Kozo
- Journal Title
  
  Current Protocols in Chemical Biology
  
  Volume: 11 Issue: 1
- DOI
  10.1002/cpch.60
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05561, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-16K18393
[Journal Article] Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons2018
- Author(s)
  Zhang XJ, Nagai T, Ahammad RU, Kuroda K, Nakamuta S, Nakano T, Yukinawa N, Funahashi Y, Yamahashi Y, Amano M, Yoshimoto J, Yamada K, and Kaibuchi K.
- Journal Title
  
  Neurochemistry International
  
  Volume: 122 Pages: 8-18
- DOI
  10.1016/j.neuint.2018.10.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07383, KAKENHI-PUBLICLY-17H05561, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-17J10615, KAKENHI-PROJECT-15K06772, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-16K18393, KAKENHI-PROJECT-18K14816
[Journal Article] Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology2018
- Author(s)
  Fujita Kyota、Chen Xigui、Homma Hidenori、Tagawa Kazuhiko、Amano Mutsuki、Saito Ayumu、Imoto Seiya、Akatsu Hiroyasu、Hashizume Yoshio、Kaibuchi Kozo、Miyano Satoru、Okazawa Hitoshi
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 433-433
- DOI
  10.1038/s41467-018-02821-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07383, KAKENHI-PROJECT-17K08725, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-17H05561, KAKENHI-PUBLICLY-17H05693, KAKENHI-PROJECT-16H02655, KAKENHI-PROJECT-16H06277
[Journal Article] Comprehensive analysis of kinase-oriented phospho-signalling pathways2018
- Author(s)
  Amano Mutsuki、Nishioka Tomoki、Tsuboi Daisuke、Kuroda Keisuke、Funahashi Yasuhiro、Yamahashi Yukie、Kaibuchi Kozo
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 165 Issue: 4 Pages: 301-307
- DOI
  10.1093/jb/mvy115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14816, KAKENHI-PUBLICLY-17H05561, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-15K06772, KAKENHI-PROJECT-16K18393, KAKENHI-PROJECT-19K16370, KAKENHI-PROJECT-17K07383
[Journal Article] Discovery of long-range inhibitory signaling to ensure single axon formation2017
- Author(s)
  Takano Tetsuya、Wu Mengya、Nakamuta Shinichi、Naoki Honda、Ishizawa Naruki、Namba Takashi、Watanabe Takashi、Xu Chundi、Hamaguchi Tomonari、Yura Yoshimitsu、Amano Mutsuki、Hahn Klaus M.、Kaibuchi Kozo
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 33-33
- DOI
  10.1038/s41467-017-00044-2
- NAID
  120006325188
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07383, KAKENHI-PROJECT-16K16147, KAKENHI-PUBLICLY-17H05561, KAKENHI-PUBLICLY-17H05693, KAKENHI-PROJECT-15J03173, KAKENHI-PROJECT-17J09461, KAKENHI-PROJECT-17H01380
[Journal Article] A FRET Biosensor for ROCK Based on a Consensus Substrate Sequence Identified by KISS Technology2017
- Author(s)
  Chunjie Li, Ayako Imanishi, Naoki Komatsu, Kenta Terai, Mutsuki Amano, Kozo Kaibuchi and Michiyuki Matsuda
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 42 Issue: 1 Pages: 1-13
- DOI
  10.1247/csf.16016
- NAID
  130005308480
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K21109, KAKENHI-PROJECT-17H01380
[Journal Article] Discovery of Long-Range Inhibitory Signaling to Ensure Single Axon Formation2017
- Author(s)
  Takano T, Wu M, Nakamuta S, Naoki H, Ishizawa N, Namba T, Watanabe T, Xu C, Hamaguchi T, Yura Y, Amano M, Hahn KM, Kaibuchi K
- Journal Title
  
  Nature Communications
  
  Volume: 印刷中
- NAID
  120006325188
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25251021
[Journal Article] Focused Proteomics Revealed a Novel Rho-kinase Signaling Pathway in the Heart2016
- Author(s)
  Yura Y, Amano M, Takefuji M, Bando T, Suzuki K, Kato K, Hamaguchi T, Hasanuzzaman Shohag M, Takano T, Funahashi Y, Nakamuta S, Kuroda K, Nishioka T, Murohara T, Kaibuchi K
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 41 Issue: 2 Pages: 105-120
- DOI
  10.1247/csf.16011
- NAID
  130005405432
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25251021, KAKENHI-PUBLICLY-15H01209, KAKENHI-PROJECT-15K06772, KAKENHI-PROJECT-16K18393
[Journal Article] Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo2016
- Author(s)
  Nagai T, Nakamuta S, Kuroda K, Nakauchi S, Nishioka T, Takano T, Zhang X, Tsuboi D, Funahashi Y, Nakano T, Yoshimoto J, Kobayashi K, Uchigashima M, Watanabe M, Miura M, Nishi A, Kobayashi K, Yamada K, Amano M, Kaibuchi K
- Journal Title
  
  Neuron
  
  Volume: 89 (3) Issue: 3 Pages: 550-65
- DOI
  10.1016/j.neuron.2015.12.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06732, KAKENHI-PROJECT-15K06772, KAKENHI-PUBLICLY-15H01283, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-25560436, KAKENHI-PROJECT-25251021, KAKENHI-PROJECT-24220007
[Journal Article] Kinase-interacting substrate screening is a novel method to identify kinase substrates.2015
- Author(s)
  Amano, M., Hamaguchi, T., Shohag, M. H., Kozawa, K., Kato, K., Zhang, X., Yura, Y., Matsuura, Y., Kataoka, C., Nishioka, T., and Kaibuchi, K.
- Journal Title
  
  J Cell Biol
  
  Volume: 209 Issue: 6 Pages: 895-912
- DOI
  10.1083/jcb.201412008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01209, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25251021
[Journal Article] Developing novel methods to search for substrates of protein kinases such as Rho-kinase.2015
- Author(s)
  Nishioka, T., Shohag, M.H., Amano, M., and Kaibuchi, K.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590357
[Journal Article] Phosphoproteomic Analysis Using the WW and FHA Domains as Biological Filters2015
- Author(s)
  Hasanuzzaman Shohag, M., Nishioka, T., Uddin Ahammad, R., Nakamuta, S., Yura, Y., Hamaguchi, T., Kaibuchi, K., and Amano, M.
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 40 Issue: 2 Pages: 95-104
- DOI
  10.1247/csf.15004
- NAID
  130005094036
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01209, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25251021
[Journal Article] <i>In vivo</i> Screening for Substrates of Protein Kinase A Using a Combination of Proteomic Approaches and Pharmacological Modulation of Kinase Activity2015
- Author(s)
  Hamaguchi, T., Nakamuta, S., Funahashi, Y., Takano, T., Nishioka, T., Shohag, M.H., Yura, Y., Kaibuchi, K., and Amano, M.
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 40 Issue: 1 Pages: 1-12
- DOI
  10.1247/csf.14014
- NAID
  130004712922
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23590357, KAKENHI-PUBLICLY-25113513, KAKENHI-PROJECT-25251021, KAKENHI-PROJECT-221S0003
[Journal Article] Developing novel methods to search for substrates of protein kinases such as Rho-kinase2015
- Author(s)
  Nishioka T, Shohag MH, Amano M, Kaibuchi K
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: - Issue: 10 Pages: 1663-1666
- DOI
  10.1016/j.bbapap.2015.03.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25251021, KAKENHI-PUBLICLY-15H01209, KAKENHI-PROJECT-221S0003
[Journal Article] Preferential targeting of p39-activated Cdk5 to Rac1-induced lamellipodia.2014
- Author(s)
  Ito, Y., Asada, A., Kobayashi, H., Takano, T., Sharma, G., Saito, T., Ohta, Y., Amano, M., Kaibuchi, K., and Hisanaga, S.
- Journal Title
  
  Molecular and Cellular Neurosciences
  
  Volume: 61 Pages: 34-45
- DOI
  10.1016/j.mcn.2014.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590357, KAKENHI-PROJECT-25290024, KAKENHI-PLANNED-26117004
[Journal Article] The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration2012
- Author(s)
  Kato, K.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 23 Issue: 13 Pages: 2593-604
- DOI
  10.1091/mbc.e11-11-0958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23590357, KAKENHI-PROJECT-23790247, KAKENHI-PROJECT-24570216, KAKENHI-PUBLICLY-23123507, KAKENHI-PUBLICLY-24113715
[Journal Article] Proteomic Screening for Rho-kinase Substrates by Combining Kinase and Phosphatase Inhibitors with 14-3-3zeta Affinity Chromatography.2012
- Author(s)
  Nishioka T., Nakayama M., Amano M. & Kaibuchi K.
- Journal Title
  
  Cell Struct Funct
  
  Volume: 37 Pages: 39-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006
[Journal Article] Proteomic Screening for Rho-kinase Substrates by Combining Kinase and Phosphatase Inhibitors with 14-3-3zeta Affinity Chromatography.2012
- Author(s)
  Nishioka, T., Nakayama, M., Amano, M., and Kaibuchi, K.
- Journal Title
  
  Cell structure and function
  
  Volume: 37 Pages: 39-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590357
[Journal Article] Distinct distribution and localization of Rho-kinase in mouse epithelial, muscle and neural tissues.2012
- Author(s)
  Iizuka, M., Kimura, K., Wang, S., Kato, K., Amano, M., Kaibuchi, K., and Mizoguchi, A.
- Journal Title
  
  Cell structure and function
  
  Volume: 37 Pages: 155-175
- NAID
  130004137587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590357
[Journal Article] The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration.2012
- Author(s)
  Kato K., Yazawa T., Taki K., Mori K., Wang S., Nishioka T., Hamaguchi T., Itoh T., Takenawa T., Kataoka C., Matsuura Y., Amano M., Murohara T. & Kaibuchi K.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 23 Pages: 2593-2604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006
[Journal Article] A proteomic approach for comprehensively screening substrates of protein kinases such as Rho-kinase.2010
- Author(s)
  Amano, M., Tsumura, Y., Taki, K., Harada, H., Mori, K., Nishioka, T., Kato, K., Suzuki, T., Nishioka, Y., Iwamatsu, A., Kaibuchi, K.
- Journal Title
  
  PLoS ONE 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590308
[Journal Article] Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity.2010
- Author(s)
  Amano M., Nakayama M. & Kaibuchi K.
- Journal Title
  
  Cytoskeleton (Hoboken)
  
  Volume: 67 Pages: 545-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006
[Journal Article] A proteomic approach for comprehensively screening substrates of protein kinases such as Rho-kinase2010
- Author(s)
  Amano, M., et al.
- Journal Title
  
  PLoS One 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20058012
[Journal Article] Rho-kinase/ROCK : A key regulator of the cytoskeleton and cell polarity.2010
- Author(s)
  Amano, M., Nakayama, M., Kaibuchi, K.
- Journal Title
  
  Cytoskeleton 67
  
  Pages: 545-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590308
[Journal Article] A proteomic approach for comprehensively screening substrates of protein kinases such as Rho-kinase2010
- Author(s)
  Amano, M., et al.
- Journal Title
  
  PLoS One 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006
[Journal Article] A proteomic approach for comprehensively screening substrates of protein kinases such as Rho-kinase.2010
- Author(s)
  Amano, M., Tsumura, Y., Taki, K., Harada, H., Mori, K., Nishioka, T., Kato, K., Suzuki, T., Nishioka, Y., Iwamatsu, A., Kaibuchi, K.
- Journal Title
  
  PLoS ONE 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006
[Journal Article] Mutation of ARHGAP9 in patients with coronary spastic angina.2010
- Author(s)
  Takefuji, M., Asano, H., Mori, K., Amano, M., Kato, K., Watanabe, T., Morita, Y., Katsumi, A., Itoh, T., Takenawa, T., Hirashiki, A., Izawa, H., Nagata, K., Hirayama, H., Takatsu, F., Naoe, T., Yokota, M., Kaibuchi, K.
- Journal Title
  
  Journal of Human Genetics 55
  
  Pages: 42-49
- NAID
  10030733231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590308
[Journal Article] Rho-kinase/ROCK : A key regulator of the cytoskeleton and cell polarity2010
- Author(s)
  Amano M., et al
- Journal Title
  
  Cytoskeleton
  
  Volume: 67 Pages: 545-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006
[Journal Article] Rho-kinase/ROCK : A key regulator of the cytoskeleton and cell polarity2010
- Author(s)
  Amano M, et al.
- Journal Title
  
  Cytoskleleton
  
  Volume: 67 Pages: 545-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590308
[Journal Article] A proteomic approach for comprehensively screening substrates of protein kinases such as Rho-kinase2010
- Author(s)
  Amano, M., et al.
- Journal Title
  
  PLoS One 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590308
[Journal Article] A proteomic approach for comprehensively screening substrates of protein kinases such as Rho-kinase.2010
- Author(s)
  Amano M., Tsumura Y., Taki K., Harada H., Mori K., Nishioka T., Kato K., Suzuki T., Nishioka Y., Iwamatsu A. & Kaibuchi K.
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006
[Journal Article] Rho-kinase Contributes to Sustained RhoA Activation through Phosphorylation of p190A RhoGAP.2009
- Author(s)
  Mori, K., Amano, M., Takefuji, M., Kato, K., Morita, Y., Nishioka, T., Matsuura, Y., Murohara, T., Kaibuchi, K.
- Journal Title
  
  The Journal of Biological Chemistry 284
  
  Pages: 5067-5076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590308
[Journal Article] Rho-kinase Contributes to Sustained RhoA Activation through Phosphorylation of p190A RhoGAP.2009
- Author(s)
  Mori, K., Amano, M., Takefuji, M., Kato, K., Morita, Y., Nishioka, T., Matsuura, Y., Murohara, T., Kaibuchi, K.
- Journal Title
  
  The Journal of Biological Chemistry 284
  
  Pages: 5067-5076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006
[Journal Article] Rho-kinase Contributes to Sustained RhoA Activation through Phosphorylation of p190A RhoGAP2009
- Author(s)
  Mori K., Amano M., Takefuji M., Kato K., Morita Y., Nishioka T., Matsuura Y., Murohara T. & Kaibuchi K.
- Journal Title
  
  J Biol Chem
  
  Volume: 284 Pages: 5067-5076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006
[Journal Article] Prognostic implication and biological roles of RhoH in acute myeloid leukaemia.2008
- Author(s)
  Iwasaki, T., Katsumi, A., Kiyoi, H., Tanizaki, R., Ishikawa, Y., Ozeki, K., Kobayashi, M., Abe, A., Matsushita, T., Watanabe, T., Amano, M., Kojima, T., Kaibuchi, K., Naoe, T.
- Journal Title
  
  European Journal of Haematology 81
  
  Pages: 454-460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590308
[Journal Article] Hydrophilic statin suppresses vein graft intimal hyperplasia via endothelial cell-tropic Rho-kinase inhibition2005
- Author(s)
  Yamanouchi D
- Journal Title
  
  J Vase Surg 42
  
  Pages: 757-764
- Data Source
  KAKENHI-PROJECT-17659382
[Journal Article] Hydrophilic statin suppresses vein graft intimal hyperplasia via endothelial cell-tropic Rho-kinase inhibition.2005
- Author(s)
  Yamanouchi D
- Journal Title
  
  JOURNAL OF VASCULAR SURGERY 42
  
  Pages: 757-764
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591326
[Journal Article] Hydrophilic statin suppresses vein graft intimal hyperplasia via endothelial celltropic Rho-kinase inhibition2005
- Author(s)
  Yamanouchi D
- Journal Title
  
  JOURNAL OF VASCULAR SURGERY 42
  
  Pages: 757-764
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591326
[Presentation] Phosphorylation of Npas4 by MAPK regulates reward-related gene expression and behaviors2020
- Author(s)
  Yasuhiro Funahashi, Anthony Ariza, Ryosuke Emi, Yifan Xu, Shan Wei, Ko Suzuki, Sachi Kozawa, Rijwan Uddin Ahammad, Mengya Wu, Tetsuya Takano, Yoshimitsu Yura, Keisuke Kuroda, Taku Nagai, Mutsuki Amano, Kiyofumi Yamada、 Kozo Kaibuchi
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] Phosphoproteomics of NMDA pathway leads to Rho-Kinase mediated synaptic plasticity through Shank3 phosphorylation.2020
- Author(s)
  Rijwan Uddin Ahammad, Yasuhiro Funahashi, Xinjian Zhang, Emran Hossen, Md. Omar Faruk, Md Hasanuzzaman Shohag, Yifan Xu, Huanhuan Wang, Shinichi Nakamuta, Keisuke Kuroda, Daisuke Tsuboi, Tomoki Nishioka, Mutsuki Amano, Kozo Kaibuchi
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] MAPKによるNpas4リン酸化は報酬関連の遺伝子発現と行動を制御する2020
- Author(s)
  船橋靖広、Anthony Ariza, 恵美亮佑、伊許凡、偉単、鈴木航、小澤祥、Rijwan Uddin Ahammad、呉夢雅、高野哲也、由良義光、黒田啓介、永井拓、天野睦紀、山田清文、貝淵弘三
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] インタラクトームを基盤としたタンパク質キナーゼの基質探索2019
- Author(s)
  天野睦紀、貝淵弘三
- Organizer
  日本プロテオーム学会2019年大会・第70回日本電気泳動学会総会　合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07383
[Presentation] Phosphoproteomics of NMDA pathway leads to Rho-Kinase mediated synaptic plasticity through Shank3 phosphorylation.2019
- Author(s)
  Rijwan Uddin Ahammad, Yasuhiro Funahashi, Emran Hossen, Md. Omar Faruk, Md Hasanuzzaman Shohag, Sachi Kozawa, Hiroki Kato, Shinichi Nakamuta, Tomoki Nishioka, Daisuke Tsuboi, Mutsuki Amano, Kozo Kaibuchi
- Organizer
  第71回日本細胞生物学会大会・第19回日本タンパク質科学学会年会　合同年次大会
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] KANPHOS (Kinase-Associated Phospho-Signaling) Platform - A comprehensive database for kinase-associated neural phosphorylation signaling"2019
- Author(s)
  Keisuke Kuroda, Mutsuki Amano, Junichiro Yoshimoto, Taku Nagai, Takayuki Kannon, Tomoki Nishioka, Shiro Usui, Kozo Kaibuchi
- Organizer
  Neuro2019 (第42回日本神経科学学会・第62回日本神経化学会大会合同大会)
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] Discovery of a key missing signaling between RhoA/Rho-kinase and Ras during LTP2019
- Author(s)
  Mengya Wu, Yasuhiro Funahashi, Tetsuya Takano, Daisuke Tsuboi, Rijwan Uddin Ahammad, Mutsuki Amano, Kozo Kaibuchi
- Organizer
  2019 ISN-ASN meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] Discovery of a key missing signaling between RhoA/Rho-kinase and Ras during LTP2019
- Author(s)
  Mengya Wu, Yasuhiro Funahashi, Tetsuya Takano, Daisuke Tsuboi, Rijwan Uddin Ahammad, Mutsuki Amano, Kozo Kaibuchi
- Organizer
  Neuro2019 (第42回日本神経科学学会・第62回日本神経化学会大会合同大会)
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] An interactome-based proteomic approach for comprehensive substrate screening of protein kinases2019
- Author(s)
  Mutsuki Amano, Kozo Kaibuchi
- Organizer
  日本プロテオーム学会2019年大会・第70回日本電気泳動学会総会　合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] KANPHOS Platform: A comprehensive database for kinase-associated neural phosphorylation signaling2019
- Author(s)
  天野睦紀、西岡朋生、吉本潤一郎、観音隆幸、臼井支朗、貝淵弘三
- Organizer
  第71回日本細胞生物学会大会・第19回日本タンパク質科学学会年会　合同年次大会
- Data Source
  KAKENHI-PROJECT-17K07383
[Presentation] Phosphorylation of Npas4 by MAPK regulates reward-related gene expression and behaviors2019
- Author(s)
  Yasuhiro Funahashi, Anthony Ariza, Ryosuke Emi, Yifan Xu, Shan Wei, Ko Suzuki, Sachi Kozawa, Tetsuya Takano, Yoshimitsu Yura, Keisuke Kuroda, Taku Nagai, Mutsuki Amano, Kiyofumi Yamada, Kozo Kaibuchi
- Organizer
  Neuro2019 (第42回日本神経科学学会・第62回日本神経化学会大会合同大会)
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] KANPHOS Platform: A comprehensive database for kinase-associated neural phosphorylation signaling2019
- Author(s)
  Mutsuki Amano, Tomoki Nishioka, Junichiro Yoshimoto, Takayuki Kannon, Shiro Usui, Kozo Kaibuchi
- Organizer
  第71回日本細胞生物学会大会・第19回日本タンパク質科学学会年会　合同年次大会
- Data Source
  KAKENHI-PROJECT-17H01380
[Presentation] KANPHOS Platform:S comprehesive database for kinase-associated eural phosphorylation signaling2018
- Author(s)
  天野睦紀
- Organizer
  第70回日本細胞生物学会　第51回日本発生生物学会合同大会
- Data Source
  KAKENHI-PROJECT-17K07383
[Presentation] KANPHOS Platform: A comprehensive database for kinase-associated neural phosphorylation signaling2018
- Author(s)
  Mutsuki Amano
- Organizer
  WCP2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07383
[Presentation] Arachidonate 12-lipoxygenase binds to active RhoA through Daam12017
- Author(s)
  Moe Murata, Akira Katsumi, Katsuhiro Kato, Asami Matsuda, Tomoki Nishioka, Mutsuki Amano, Tadashi Matsushita, Hitoshi Kiyoi, Mitsuo Maruyama, Tetsuhito Kojima, Kozo Kaibuchi
- Organizer
  第39回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09451
[Presentation] Arachidonate 12-lipoxygenase binds to active RhoA through Daam12017
- Author(s)
  Moe Murata, Akira Katsumi, Katsuhiro Kato, Asami Matsuda, Tomoki Nishioka, Mutsuki Amano, Tadashi Matsushita, Hitoshi Kiyoi, Mitsuo Maruyama, Tetsuhito Kojima, Kozo Kaibuchi
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09451
[Presentation] KANPHOS (Kinase-Associated Phospho-Signaling) Platform ―新規リン酸化DBプラットフォーム―2017
- Author(s)
  天野睦紀、西岡朋生、黒田啓介、吉本潤一郎、観音隆幸、臼井支朗、貝淵弘三
- Organizer
  第69回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-17K07383
[Presentation] リン酸化プロテオミクスによるニューロモジュレーターシグナルの解明2017
- Author(s)
  天野睦紀
- Organizer
  第39回神経組織培養研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07383
[Presentation] 血球特異的Rho ファミリー蛋白RhoH はT cell activation GTPase activating protein(TAGAP) を介してRac を不活性化する2015
- Author(s)
  松田亜沙実、勝見章、天野睦紀、永田泰之、大西一功、清井仁、直江知樹
- Organizer
  第74 回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K09451
[Presentation] 血球特異的なRhoファミリー蛋白RhoHによるRacの不活性化機構はT細胞活性化GAP(TAGAP)を介する2015
- Author(s)
  松田亜沙実、勝見　章、天野睦紀、永田泰之、小野孝明、大西一功、丸山光生、貝淵弘三、清井　仁、直江知樹
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  ANAクラウンプラザホテル金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K09451
[Presentation] Rho H, a hematopoietic cell specific Rho protein, Deactivates Rac through T cell activation GTPase activating protein (TAGAP)2015
- Author(s)
  Asami Matsuda , Akira Katsumi , Mutsuki Amano , Yasuyuki Nagata , Takaaki Ono , Mitsuo Maruyama , Hiroshi Kiyoi, Tomoki Naoe, Kozo Kaibuchi
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K09451
[Presentation] Functional studies of the CDKL5, a causative gene of neurodevelopmental disorder, by interactome screening and loss-of-function analysis2013
- Author(s)
  Kosuke Okuda, Aya Watanabe, Shizuka Kobayashi, Toshiya Manabe, Keizo Takao, Tsuyoshi Miyakawa, Masahiro Fukaya, Hiroyuki Sakagami, Tomoki Nishioka, Mutsuki Amano, Kozo Kaibuchi, Masashi Mizuguchi, Teruyuki Tanaka
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23500381
[Presentation] 神経関連キナーゼの基質の網羅的解析2013
- Author(s)
  天野睦紀
- Organizer
  第13回日本蛋白質科学学会年会
- Place of Presentation
  とりぎん文化会館（鳥取市）
- Data Source
  KAKENHI-PROJECT-23590357
[Presentation] 神経関連キナーゼの基質の網羅的解析2013
- Author(s)
  天野　睦紀
- Organizer
  第13回日本蛋白質科学学会年会
- Place of Presentation
  とりぎん文化会館　（鳥取市）
- Data Source
  KAKENHI-PROJECT-25251021
[Presentation] タンパク質相互作用を利用したキナーゼ基質の網羅的解析2011
- Author(s)
  天野睦紀
- Organizer
  第2回神経科学と構造生物学の融合
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-23590357
[Presentation] 蛋白質相互作用を利用したキナーゼ基質の網羅的解析2011
- Author(s)
  天野睦紀
- Organizer
  日本プロテオーム学会2011年大会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-23590357
[Presentation] A proteomic approach for comprehensively screening substrates of proteinkinases2010
- Author(s)
  Amano M.
- Organizer
  HUPO 2010
- Place of Presentation
  Sydney, Australia
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] A proteomic approach for comprehensively screening substrates of proteinkinases2010
- Author(s)
  Amano M.
- Organizer
  Neuro 2010
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] 蛋白質問相互作用を利用したキナーゼの新規基質のスクリーニング2010
- Author(s)
  天野睦紀
- Organizer
  第35回日本医用マススペクトル学会
- Place of Presentation
  名古屋
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] A proteomic approach for comprehensively screening substrates of protein kinases.2010
- Author(s)
  天野睦紀
- Organizer
  Neuro 2010
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] Roles of Rho/Rho-kinase in Cellular functions and Diseases2009
- Author(s)
  Mutsuki Amano
- Organizer
  10th International Symposium on Mechanisms of Vasodilation
- Place of Presentation
  Matsushima, Japan
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] 蛋白質間相互作用を利用したキナーゼ基質の網羅的解析2009
- Author(s)
  天野睦紀
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] 蛋白質間相互作用を利用したキナーゼ基質の網羅的解析2009
- Author(s)
  天野睦紀
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20058012
[Presentation] Rho-kinaseによるRhoの持続的活性化と血管平滑筋収縮2009
- Author(s)
  天野睦紀
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20058012
[Presentation] Screening of Protein kinase Substrates by an Interactome Approach.2009
- Author(s)
  天野睦紀
- Organizer
  Tsuruoka Proteomics Meeting 2009
- Place of Presentation
  Tsuruoka, Japan
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] Rho-kinaseによるRhoの持続的活性化と血管平滑筋収縮2009
- Author(s)
  天野睦紀
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] Screening of Protein kinase Substrates by an Interactome Approach2009
- Author(s)
  天野睦紀
- Organizer
  Tsuruoka Proteomics Meeting 2009
- Place of Presentation
  鶴岡
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20058012
[Presentation] 蛋白質間相互作用を利用したキナーゼ基質の網羅的解析2009
- Author(s)
  天野睦紀
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20058012
[Presentation] Roles of Rho/Rho-kinase in Cellular functions and Diseases.2009
- Author(s)
  天野睦紀
- Organizer
  10th International Symposium on Mechanisms of Vasodilation
- Place of Presentation
  Matsushima, Japan
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] 蛋白質間相互作用を利用したキナーゼ基質の網羅的解析2009
- Author(s)
  天野睦紀
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] 蛋白質間相互作用を利用したキナーゼ基質の網羅的解析2009
- Author(s)
  天野睦紀
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] Rho-kinasebによるRhoの持続的活性化と血管平滑筋収縮2009
- Author(s)
  天野睦紀
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] Rho-kinase and Rho family GTPase signaling2008
- Author(s)
  Mutsuki Amano
- Organizer
  FASEB Suramer Research Conferences
- Place of Presentation
  Vermont, USA
- Data Source
  KAKENHI-PROJECT-20227006
[Presentation] Rho-kinase and Rho family GTPase signaling.2008
- Author(s)
  天野睦紀
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Vermont, USA
- Year and Date
  2008-07-14
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] Rho-kinase and Rho family GTPase signaling2008
- Author(s)
  Mutsuki Amano
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Vermont, USA
- Data Source
  KAKENHI-PROJECT-20590308
[Presentation] Rho-kinase and Rho family GTPase signaling2008
- Author(s)
  Mutsuki Amano
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Vermont, USA
- Data Source
  KAKENHI-PROJECT-20058012
[Presentation] Rho family signaling and Rho-kinaw2007
- Author(s)
  Amano, M., Kaibuchi, K
- Organizer
  The 80th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Nagoya
- Year and Date
  2007-08-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590261
[Presentation] RhoファミリーシグナリングとRho-kinase2007
- Author(s)
  天野睦紀、貝淵弘三
- Organizer
  第11回Molecular Cardiovascular Conference
- Place of Presentation
  キロロ
- Year and Date
  2007-09-15
- Data Source
  KAKENHI-PROJECT-18590261
[Presentation] Rho family signaling and Rho-kin2007
- Author(s)
  Amano, M., Kaibuchi, K
- Organizer
  The 11th Molecular Cardiovascular Conference
- Place of Presentation
  Eiroro
- Year and Date
  2007-09-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590261
[Presentation] RhoファミリーシグナリングとRho-kinase2007
- Author(s)
  天野睦紀、貝淵弘三
- Organizer
  第80回日本薬理学会
- Place of Presentation
  名古屋
- Year and Date
  2007-03-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590261
[Presentation] RhoファミリーシグナリングとRho-kinase2007
- Author(s)
  天野睦紀、貝淵弘三
- Organizer
  第11回Molecular Cardiovascular Confbrence
- Place of Presentation
  キロロ
- Year and Date
  2007-09-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590261
[Presentation] Roles of Rho-kinase in cellular functions2006
- Author(s)
  Amano, M and Kaibuchi, K
- Organizer
  2006 FASEB Summer Research Confbrence
- Place of Presentation
  Snowmass, USA
- Year and Date
  2006-08-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590261
[Presentation] Roles of Rho-kinase in cellular functions2006
- Author(s)
  Amano, M., Kaibuchi, K
- Organizer
  2006 FASEB Summer Research Conference
- Place of Presentation
  Snowmass, USA
- Year and Date
  2006-08-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590261
[Presentation] Protein phosphorylation remains a black box in signal transduction: Developing a new method to search for substrates of polarity kinases including Rho-kinase
- Author(s)
  Mutsuki Amano
- Organizer
  The 4th Asia Pacific Protein Association (APPA) Conference
- Place of Presentation
  Jeju, Korea
- Year and Date
  2014-05-17 – 2014-05-20
- Invited
- Data Source
  KAKENHI-PROJECT-25251021
[Presentation] リン酸化プロテオミクスによるモノアミンシグナルの解明
- Author(s)
  天野睦紀
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場、愛知県、名古屋市
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-23590357
[Presentation] Systematic Substrate Screening of Protein Kinases using a Functional Proteomic Approach
- Author(s)
  Mutsuki Amano
- Organizer
  8th International Conference Inhibitors of Protein Kinases (IPK2014)
- Place of Presentation
  Warsaw, Poland
- Year and Date
  2014-09-21 – 2014-09-25
- Data Source
  KAKENHI-PROJECT-23590357
[Presentation] Systematic Substrate Screening of Protein kinases in brain by a proteomic approach
- Author(s)
  天野睦紀
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590357
[Presentation] Systematic Substrate Screening of Protein Kinases using a Functional Proteomic Approach
- Author(s)
  Mutsuki Amano
- Organizer
  8th International Conference Inhibitors of Protein Kinases (IPK2014)
- Place of Presentation
  Warsaw, Poland
- Year and Date
  2014-09-21 – 2014-09-25
- Data Source
  KAKENHI-PROJECT-25251021
[Presentation] Protein phosphorylation remains a black box in signal transduction: Developing a new method to search for substrates of polarity kinases including Rho-kinase
- Author(s)
  Mutsuki Amano
- Organizer
  The 4th Asia Pacific Protein Association (APPA) Conference
- Place of Presentation
  Jeju, Korea
- Year and Date
  2014-05-17 – 2014-05-20
- Data Source
  KAKENHI-PROJECT-23590357
[Presentation] 神経関連キナーゼの基質の網羅的解析
- Author(s)
  天野睦紀
- Organizer
  第２７回日本医用マススペクトル学会東海支部講演会
- Place of Presentation
  名古屋大学医学部附属病院（名古屋市）
- Invited
- Data Source
  KAKENHI-PROJECT-23590357
[Presentation] 神経関連キナーゼの基質の網羅的解析
- Author(s)
  天野　睦紀
- Organizer
  第２７回日本医用マススペクトル学会東海支部講演会
- Place of Presentation
  名古屋大学医学部　（名古屋市）
- Invited
- Data Source
  KAKENHI-PROJECT-25251021
[Presentation] 神経関連キナーゼの基質の網羅的解析
- Author(s)
  天野睦紀
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590357

1. KAIBUCHI Kozo (00169377)

# of Collaborated Projects: 18 results

# of Collaborated Products: 32 results
2. NAOYUKI Inagaki (20223216)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. QUADOTA Hiroshi (10294282)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. WATANABE Takashi (10402562)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. NISHIOKA Tomoki (70435105)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
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# of Collaborated Products: 5 results
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8. KOMORI Kimihiro (40225587)

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9. YAMAMOTO Kiyohito (10298359)

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10. KOBAYASHI Masayoshi (60329381)

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11. ARIMURA Nariko (20420375)

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12. MARUYAMA Mitsuo (00212225)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
13. MUROHARA Toyoaki (90299503)

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14. 黒田啓介 (80631431)

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15. MORI Daisuke (00381997)

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16. TSUBOI Daisuke (80584672)

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17. Tanaka Teruyuki (10246647)

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18. MATSUSHITA Tadashi (30314008)

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19. KOMORI Takahide (50251294)

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20. FUJIOKA Manabu (70362788)

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22. KURODA Shinya (50273850)

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23. TAYA Shinichiro (60362232)

# of Collaborated Projects: 1 results

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24. KATONO Yuki (30378088)

# of Collaborated Projects: 1 results

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25. Hoshino MIkio (70301273)

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26. 深田正紀 (00335027)

# of Collaborated Projects: 1 results

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27. 水口雅 (20209753)

# of Collaborated Projects: 1 results

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28. 中牟田信一 (20647474)

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29. 井上高良 (20370984)

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30. 菅野康太 (80722470)

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31. 永井拓 (10377426)

# of Collaborated Projects: 1 results

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32. 船橋靖広 (00749913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
33. 柳久乃 (40868949)

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34. 下野洋平 (90594630)

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35. 榎本篤 (20432255)

# of Collaborated Projects: 1 results

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36. 奥尚久

# of Collaborated Projects: 1 results

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37. Ryotaro Koike

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. OUCHI NORIYUKI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. OHASHI Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. SHIOZAWA Seiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. UCHIGASHIMA Motokazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 市之瀬敏晴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 関根章博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 東島恵美子(宍戸恵美子)

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AMANO Mutsuki 天野 睦紀

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Analysis of substrate recognition and regulatory mechanisms for protein kinases.Principal Investigator

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Involvement of small GTPase Rho family signaling pathways in diseases.Principal Investigator

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細胞増殖・分化に関わる蛋白質リン酸化酵素の新規基質スクリーニング法の開発Principal Investigator

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AMANO Mutsuki 天野睦紀