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MASAMUNE ATSUSHI  正宗 淳

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MASAMUNE Atsushi  正宗 淳

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Researcher Number 90312579
Other IDs
Affiliation (Current) 2025: 東北大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2018 – 2025: 東北大学, 医学系研究科, 教授
2016 – 2017: 東北大学, 医学系研究科, 准教授
2011 – 2016: 東北大学, 医学(系)研究科(研究院), 准教授
2014: 東北大学, 大学院医学系研究科, 准教授
2013 – 2014: 東北大学, 医学系研究科, 准教授 … More
2012: 東北大学, 大学院・医学系研究科, 准教授
2007 – 2011: Tohoku University, TOHOKU UNIVERSITY HOSPITAL, Assistant Professor
2005 – 2006: TOHOKU UNIVERSITY, HOSPITAL, RESEARCH ASSOCIATE, 病院, 助手
2004 – 2006: 東北大学, 病院・助手
2004: 東北大学, 大学病院, 助手
2003: 東北大学, 医学部附属病院, 助手
2001 – 2002: Tohoku University, Graduate School of Medicine, Research Associate, 大学院・医学系研究科, 助手
2001: 東北大学, 大学院医学系研究科, 助手
2000: 東北大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related / Gastroenterology / Medium-sized Section 53:Organ-based internal medicine and related fields
Except Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related / Basic Section 47060:Clinical pharmacy-related / Gastroenterology / Applied pharmacology
Keywords
Principal Investigator
膵癌 / 膵線維化 / 膵星細胞 / 酸化ストレス / 慢性膵炎 / galectin / 上皮間葉転換 / マイクロRNA / 膵炎 / シグナル伝達 … More / MAP kinase / 活性硫黄 / 活性イオウ / 膵癌早期診断 / 細胞老化 / iPS細胞 / 遺伝性膵炎 / 膵癌モデルマウス / Keap1 / Nrf2 / KPCマウス / Chronic pancreatitis / Pancreatic fibrosis / Pancreatic stellate cells / 自然免疫 / 細胞内シグナル伝達 / toll-like receptor / desmoplastic reaction / polyphenol / glycoconjugates / pancreatic fibrosis / pancreatic stellate cells / pancreatic cancer / カテキン / endothelin-1 / PAR-2 / トリプシン / ポリフェノール / 糖鎖 / 癌幹細胞 / 膵臓癌 / stemness / 幹細胞 / アンギオテンシン受容体拮抗剤 / 遺伝子 / 薬剤耐性 / interleukin-33 / 放射線治療 / 線維化 / PPAR / MAP kinases / アルコール / 急性膵炎 / Rho / 遺伝子治療 / セラミド / スフィンゴ脂質 / IL-8 / アポトーシス … More
Except Principal Investigator
膵癌 / 慢性膵炎 / 酸化ストレス / 膵星細胞 / 線維化 / 膵がん / 膵炎 / 急性膵炎 / 薬物送達 / 細胞外基質 / 三次元培養法 / 栄養 / ICAM-1 / PDTC / NF-κB / 間質 / 腫瘍微小環境 / 三次元培養 / 膵臓がん / 次世代シークエンサー / マイクロRNA / 遺伝子解析 / 線維化障壁 / 薬剤送達 / 難治固形腫瘍 / 内外分泌相関 / 早期慢性膵炎 / 立体培養 / 膵臓星状細胞(PSC) / 膵臓星状細胞 / 線維芽細胞 / ウェアラブル端末 / 身体活動量 / サルコペニア / 身体活動 / 骨格筋量 / 膵癌間質 / Keap1 / 胆管癌 / N-accetyl cysteme(NAC) / therapy / severe acute pancreatitis / NLS- 1κBα / recombinant adenoiviral vector / 遺伝子治療 / アデノウィルスベクター / 組み換えアデノウイル / NLS / NFκB / Iκβα / 組み替えアデノウィルス / NLS-IkBα / NF-kB / N-acetyl cysteine(NAC) / 治療 / 組み換えアデノウィルス / NLS-IκBα / 重症急性膵炎 / ミトコンドリア / miR-197 / PSC-CM / 細胞内代謝 / microbiome / 膵癌モデルマウス / 新規モデル / ナノバイオ / がん / 細胞・組織 / 腫瘍 / ナノ薬理学 / 組織・細胞 / SNP / 膵炎関連遺伝子 / 次世代シークエンス / 膵線維化 / 糖尿病 / 変異 / 国際情報交換 / 膵臓学 / 胆道学 / CDCP1 / EMT / cancer stem cell / microRNA / 質量分析 / 細胞内シグナル / Toll-like recetor / Toll-like recepto / CD14 / 遺伝子多型 / 小胞体ストレス / シグナル伝達 / アルコール / スプライシング / トリプシン / スプラシング / ナノテクノロジー / 膵外分泌 / 遺伝子 / SPINK1 / 遺伝子変異 / CDE膵炎 / TCA膵炎 / Macrophage migration inhibitory factor(MIF) / サイトカイン / MIF Less
  • Research Projects

    (34 results)
  • Research Products

    (250 results)
  • Co-Researchers

    (21 People)
  •  次世代放射光で「視る」膵癌多様性と治療応用Principal Investigator

    • Principal Investigator
      正宗 淳
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  Overcoming fibrotic barriers to nanomedicine delivery in pancreatic cancer

    • Principal Investigator
      狩野 光伸
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Okayama University
  •  Development of therapeutic strategies to overcome fibrotic barriers to nanomedicine in pancreatic cancer via targeting of extracellular matrix signaling

    • Principal Investigator
      田中 啓祥
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Okayama University
  •  ストレス応答機構制御による腫瘍免疫賦活療法の開発

    • Principal Investigator
      濱田 晋
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  硫黄生物学から紐解く膵癌難治化機構の解明と治療応用Principal Investigator

    • Principal Investigator
      正宗 淳
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  Development of biomarkers for early diagnosis of chronic pancreatitis

    • Principal Investigator
      Kikuta Kazuhiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  Development of novel therapy for pancreatic cancer targeting Nrf2-dependent reprogramming

    • Principal Investigator
      Hamada Shin
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  Development of hybrid PET probe for early detection of pancreatic cancerPrincipal Investigator

    • Principal Investigator
      Masamune Atsushi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Tohoku University
  •  Development of novel therapy for pancreatic cancer based on the regulation of oxidative stress responsesPrincipal Investigator

    • Principal Investigator
      Masamune Atsushi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  An investigation on the physical activity of patients with chronic pancreatitis

    • Principal Investigator
      KIKUTA Kazuhiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  Establishing a 3D model of fibrosis in pancreatic cancer and analysis of interaction between tumor cells and stellate cells

    • Principal Investigator
      Kano Mitsunobu
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Okayama University
  •  Role of oxidative stress response in cholangiocarcinoma

    • Principal Investigator
      Hamada Shin
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Analysis of immune suppressing mechanism of pancreatic cancer stroma

    • Principal Investigator
      Shimosegawa Tooru
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Establishment of hereditary pancreatitis patient-derived iPS cellsPrincipal Investigator

    • Principal Investigator
      Masamune Atsushi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Role of oxidative stress response in pancreatic diseases and therapeutic applicationPrincipal Investigator

    • Principal Investigator
      Masamune Atsushi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Investigation of intractability of pancreatic cancer by using 3D culture of pancreatic stellate cells

    • Principal Investigator
      Mitsunobu Kano
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Okayama University
  •  Analysis of selection pressure in pancreatic carcinogenesis

    • Principal Investigator
      Shimosegawa Tooru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Identification of Warburg effect inducer in pancreatic cancer

    • Principal Investigator
      Hamada Shin
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Analysis of pancreatitis-associated gene variation by next-generation sequencing

    • Principal Investigator
      SHIMOSEGAWA Tooru
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  The prevention of pancreatic diseases targeting for the pancreatic stem/progenitor cell niche

    • Principal Investigator
      KIKUTA Kazuhiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Novel therapeutic strategy targeting pancreatic cancer stem cell-niche

    • Principal Investigator
      SHIMOSEGAWA Tooru
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Stellate cell-mediated regulation of stemness maintenance in pancreatic cancer stem cellsPrincipal Investigator

    • Principal Investigator
      MASAMUNE Atsushi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Analysis of pancreatitis-associated genetic disorders by whole exome sequencing

    • Principal Investigator
      SHIMOSEGAWA Tooru
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  質量分析による膵液中変異蛋白の網羅的解析と膵疾患早期診断法の確立

    • Principal Investigator
      下瀬川 徹
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Elucidation of the pathogenesis of alcoholic pancreatitis and development of its prevention

    • Principal Investigator
      SATOH Akihiko
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Elucidation of the micro-RNA-mediated regulation of pancreatic stellate cell activation and its therapeutic applications.Principal Investigator

    • Principal Investigator
      MASAMUNE Atsushi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  血中変異PSTI蛋白マススクリーニングによる早期慢性膵炎診断法の開発

    • Principal Investigator
      下瀬川 徹
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Activation of pancreatic stellate cells mediated by Toll-like receptorPrincipal Investigator

    • Principal Investigator
      MASAMUNE Atsushi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  ナノテクノロジーを用いた慢性膵炎診断法の開発と膵導管細胞障害原因遺伝子の検討

    • Principal Investigator
      下瀬川 徹
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Development of new therapy targetting pancreatic cancer-stellate cell interactionPrincipal Investigator

    • Principal Investigator
      MASAMUNE Atsushi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      TOHOKU UNIVERSITY
  •  MIFを分子標的とした重症急性膵炎の治療法の開発

    • Principal Investigator
      SHIMOSEGAWA Tooru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  膵星細胞の活性化機構の解明と膵星細胞をターゲットにした新しい膵炎治療法の開発Principal Investigator

    • Principal Investigator
      正宗 淳
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  スフィンゴ脂質をターゲットにした新しい膵癌治療法の開発Principal Investigator

    • Principal Investigator
      正宗 淳
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Development of a novel therapy for severe acute pancreatitis by a specific inhibiiton of NF-κB- -Basic analysis using recombinant NLS-I k Bαadenoviral vector-

    • Principal Investigator
      SHIMOSEGAWA Tooru
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      TOHOKU UNIVERSITY

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Targeting ROCK2 improves macromolecular permeability in a 3D fibrotic pancreatic cancer microenvironment model2024

    • Author(s)
      Tanaka Hiroyoshi Y.、Nakazawa Takuya、Miyazaki Takuya、Cabral Horacio、Masamune Atsushi、Kano Mitsunobu R.
    • Journal Title

      Journal of Controlled Release

      Volume: 369 Pages: 283-295

    • DOI

      10.1016/j.jconrel.2024.03.041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K06279, KAKENHI-PROJECT-23K27344
  • [Journal Article] 慢性膵炎における簡易型自記式食事歴法質問票の有用性の検討2023

    • Author(s)
      菊田和宏、松本諒太郎、滝川哲也、濱田晋、正宗淳
    • Journal Title

      消化と吸収

      Volume: 45 Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Journal Article] Therapeutic Strategies to Overcome Fibrotic Barriers to Nanomedicine in the Pancreatic Tumor Microenvironment2023

    • Author(s)
      Tanaka Hiroyoshi Y.、Nakazawa Takuya、Enomoto Atsushi、Masamune Atsushi、Kano Mitsunobu R.
    • Journal Title

      Cancers

      Volume: 15 Issue: 3 Pages: 724-724

    • DOI

      10.3390/cancers15030724

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16989, KAKENHI-PROJECT-23K24312
  • [Journal Article] Severity of acute pancreatitis in patients with inflammatory bowel disease in the era of biologics: A propensity-score-matched analysis using a nationwide database in Japan2023

    • Author(s)
      Moroi R, Tarasawa K, Ikeda M, Matsumoto R, Shimoyama Y, Naito T, Takikawa T, Shiga H, Hamada S, Kakuta Y, Kikuta K, Fushimi K, Fujimori K, Kinouchi Y, Masamune A
    • Journal Title

      JGH Open

      Volume: 7 Issue: 1 Pages: 40-47

    • DOI

      10.1002/jgh3.12849

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Journal Article] 慢性膵炎における飲酒量と生活習慣の関連2023

    • Author(s)
      菊田和宏、松本諒太郎、滝川哲也、正宗淳
    • Journal Title

      アルコール医学生物学

      Volume: 42 Pages: 54-59

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Journal Article] アルコール性慢性膵炎における飲酒・喫煙と併存疾患の現況2022

    • Author(s)
      菊田和宏, 正宗淳.
    • Journal Title

      アルコールと医学生物学

      Volume: 41 Pages: 32-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Journal Article] Acute Pancreatitis in Japan: Comparison of Before and After Revision of the Clinical Guidelines.2022

    • Author(s)
      Ikeda M, Hamada S, Kikuta K, Takikawa T, Yoshida N, Matsumoto R, Tanaka Y, Kataoka F, Sasaki A, Tarasawa K, Fujimori K, Fushimi K, Masamune A.
    • Journal Title

      Pancreas

      Volume: 51(3) Issue: 3 Pages: 261-268

    • DOI

      10.1097/mpa.0000000000002009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10550, KAKENHI-PROJECT-21K07930
  • [Journal Article] HIF-1 and NRF2; Key molecules for malignant phenotypes of pancreatic cancer.2022

    • Author(s)
      Hamada S, Matsumoto R, Masamune A.
    • Journal Title

      Cancers (Basel).

      Volume: 14 Issue: 2 Pages: 411-411

    • DOI

      10.3390/cancers14020411

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03631
  • [Journal Article] 高齢者慢性膵炎における疼痛管理の実態2022

    • Author(s)
      菊田和宏, 濱田晋, 正宗淳.
    • Journal Title

      胆膵の病態生理

      Volume: 38 Pages: 17-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Journal Article] The revised diagnostic criteria and prospects of chronic pancreatitis2021

    • Author(s)
      菊田 和宏、正宗 淳
    • Journal Title

      Nippon Shokakibyo Gakkai Zasshi

      Volume: 118 Issue: 12 Pages: 1089-1097

    • DOI

      10.11405/nisshoshi.118.1089

    • NAID

      130008127627

    • ISSN
      0446-6586, 1349-7693
    • Year and Date
      2021-12-10
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Journal Article] Nrf2 Activation Sensitizes K-Ras Mutant Pancreatic Cancer Cells to Glutaminase Inhibition2021

    • Author(s)
      Hamada S, Matsumoto R, Tanaka Y, Taguchi K, Yamamoto M, Masamune A.
    • Journal Title

      Int J Mol Sci.

      Volume: 22 Issue: 4 Pages: 1870-1870

    • DOI

      10.3390/ijms22041870

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08300, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H03631
  • [Journal Article] Nrf2 expression in pancreatic stellate cells promotes progression of cancer.2021

    • Author(s)
      Tanaka Y, Hamada S, Matsumoto R, Taguchi K, Yamamoto M, Masamune A.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol.

      Volume: 321 Issue: 4 Pages: G378-G388

    • DOI

      10.1152/ajpgi.00120.2021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03631
  • [Journal Article] Nuclear factor erythroid 2-related factor 2 depletion sensitizes pancreatic cancer cells to gemcitabine via aldehyde dehydrogenase 3a1 repression.2021

    • Author(s)
      Matsumoto R, Hamada S, Tanaka Y, Taguchi K, Yamamoto M, Masamune A.
    • Journal Title

      J Pharmacol Exp Ther.

      Volume: 379 Issue: 1 Pages: 33-40

    • DOI

      10.1124/jpet.121.000744

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03631
  • [Journal Article] Keap1 deletion accelerates mutant K-ras/p53-driven cholangiocarcinoma.2020

    • Author(s)
      Nabeshima T, Hamada S, Taguchi K, Tanaka Y, Matsumoto R, Yamamoto M, Masamune A.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol.

      Volume: 318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09452
  • [Journal Article] Heterotypic 3D pancreatic cancer model with tunable proportion of fibrotic elements2020

    • Author(s)
      Tanaka Hiroyoshi Y.、Kurihara Tsuyoshi、Nakazawa Takuya、Matsusaki Michiya、Masamune Atsushi、Kano Mitsunobu R.
    • Journal Title

      Biomaterials

      Volume: 251 Pages: 120077-120077

    • DOI

      10.1016/j.biomaterials.2020.120077

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16989, KAKENHI-PROJECT-18H02797
  • [Journal Article] Keap1 deletion accelerates mutant K-ras/p53-driven cholangiocarcinoma.2020

    • Author(s)
      Nabeshima T, Hamada S, Taguchi K, Tanaka Y, Matsumoto R, Yamamoto M, Masamune A.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol.

      Volume: 318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03631
  • [Journal Article] Employment of patients with chronic pancreatitis in Japan2020

    • Author(s)
      菊田和宏、濱田晋、粂潔、正宗淳
    • Journal Title

      Suizo

      Volume: 35 Issue: 2 Pages: 187-192

    • DOI

      10.2958/suizo.35.187

    • NAID

      130007871552

    • ISSN
      0913-0071, 1881-2805
    • Year and Date
      2020-04-30
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Journal Article] Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis.2019

    • Author(s)
      Lasher D, Szabo A, Masamune A, Chen JM, Xiao X, Whitcomb DC, Barmada MM, Ewers M, Ruffert C, Paliwal S, Issarapu P, Bhaskar S, Mani KR, Chandak GR, Laumen H, Masson E, Kume K, Hamada S, Nakano E, Seltsam K, Bugert P, Muller T, Groneberg DA, Shimosegawa T, Rosendahl J, Ferec C, Lowe ME, Witt H, Sahin-Toth M.
    • Journal Title

      Am J Gastroenterol.

      Volume: - Issue: 6 Pages: 974-983

    • DOI

      10.14309/ajg.0000000000000051

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15421
  • [Journal Article] Pancreatic stellate cells derived from human pancreatic cancer demonstrate aberrant SPARC-dependent ECM remodeling in 3D engineered fibrotic tissue of clinically relevant thickness2019

    • Author(s)
      Tanaka Hiroyoshi Y.、Kitahara Kentaro、Sasaki Naoki、Nakao Natsumi、Sato Kae、Narita Hirokazu、Shimoda Hiroshi、Matsusaki Michiya、Nishihara Hiroshi、Masamune Atsushi、Kano Mitsunobu R.
    • Journal Title

      Biomaterials

      Volume: 192 Pages: 355-367

    • DOI

      10.1016/j.biomaterials.2018.11.023

    • NAID

      120006900803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H02099, KAKENHI-PROJECT-18H02797
  • [Journal Article] Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma2018

    • Author(s)
      Hamada Shin、Shimosegawa Tooru、Taguchi Keiko、Nabeshima Tatsuhide、Yamamoto Masayuki、Masamune Atsushi
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 314 Issue: 1 Pages: G65-G74

    • DOI

      10.1152/ajpgi.00228.2017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04804
  • [Journal Article] Elucidating the link between collagen and pancreatic cancer: what’s next?2018

    • Author(s)
      Hamada Shin、Masamune Atsushi
    • Journal Title

      Expert Rev Gastroenterol Hepatol.

      Volume: 12 Issue: 4 Pages: 315-317

    • DOI

      10.1080/17474124.2018.1448268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09452
  • [Journal Article] Exosomes derived from pancreatic cancer cells induce activation and profibrogenic activities in pancreatic stellate cells2018

    • Author(s)
      Masamune Atsushi、Yoshida Naoki、Hamada Shin、Takikawa Tetsuya、Nabeshima Tatsuhide、Shimosegawa Tooru
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 495 Issue: 1 Pages: 71-77

    • DOI

      10.1016/j.bbrc.2017.10.141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04804
  • [Journal Article] Nrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis2017

    • Author(s)
      Hamada Shin、Taguchi Keiko、Masamune Atsushi、Yamamoto Masayuki、Shimosegawa Tooru
    • Journal Title

      Carcinogenesis

      Volume: 38 Issue: 6 Pages: 661-670

    • DOI

      10.1093/carcin/bgx043

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04804
  • [Journal Article] Exosomes Derived From Pancreatic Stellate Cells: MicroRNA Signature and Effects on Pancreatic Cancer Cells.2017

    • Author(s)
      Takikawa T, Masamune A, Yoshida N, Hamada S, Kogure T, Shimosegawa T.
    • Journal Title

      Pancreas.

      Volume: 46 Issue: 1 Pages: 19-27

    • DOI

      10.1097/mpa.0000000000000722

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04804, KAKENHI-PROJECT-26293171, KAKENHI-PROJECT-26461029
  • [Journal Article] Kindlin-2 in pancreatic stellate cells promotes the progression of pancreatic cancer.2017

    • Author(s)
      Yoshida N, Masamune A, Hamada S, Kikuta K, Takikawa T, Motoi F, Unno M, Shimosegawa T.
    • Journal Title

      Cancer Lett.

      Volume: 390 Pages: 103-114

    • DOI

      10.1016/j.canlet.2017.01.008

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04804, KAKENHI-PROJECT-26293171
  • [Journal Article] IL-6/STAT3 Plays a Regulatory Role in the Interaction Between Pancreatic Stellate Cells and Cancer Cells.2016

    • Author(s)
      Hamada S, Masamune A, Yoshida N, Takikawa T, Shimosegawa T.
    • Journal Title

      Dig Dis Sci.

      Volume: Epub ahead of print

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04804
  • [Journal Article] IL-6/STAT3 Plays a Regulatory Role in the Interaction Between Pancreatic Stellate Cells and Cancer Cells.2016

    • Author(s)
      Hamada S, Masamune A, Yoshida N, Takikawa T, Shimosegawa T.
    • Journal Title

      Dig Dis Sci.

      Volume: Epub ahead of print

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293171
  • [Journal Article] IL-6/STAT3 Plays a Regulatory Role in the Interaction Between Pancreatic Stellate Cells and Cancer Cells.2016

    • Author(s)
      Hamada S, Masamune A, Yoshida N, Takikawa T, Shimosegawa T.
    • Journal Title

      Dig Dis Sci.

      Volume: Epub ahead of print

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461029
  • [Journal Article] Targeted Next-Generation Sequencing Effectively Analyzed the Cystic Fibrosis Transmembrane Conductance Regulator Gene in Pancreatitis.2015

    • Author(s)
      Nakano E, Masamune A, Niihori T, Kume K, Hamada S, Aoki Y, Matsubara Y, Shimosegawa T.
    • Journal Title

      Dig Dis Sci.

      Volume: [Epub ahead of print]

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670363
  • [Journal Article] 全国調査からみた急性膵炎における耐糖能障害2014

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Journal Title

      消化と吸収

      Volume: 36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] The zinc transporter LIV-1 is a novel regulator of stemness in pancreatic cancer cells2014

    • Author(s)
      Unno J, Masamune A, Hamada S, Shimosegawa T.
    • Journal Title

      Scand J Gastroenterol

      Volume: 49 Issue: 2 Pages: 215-221

    • DOI

      10.3109/00365521.2013.865075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] Sudden disappearance of the blood flow in a case of pancreatic acinar cell carcinoma2014

    • Author(s)
      Kanno A, Masamune A, Hamada S, Kikuta K, Kume K, Hirota M, Shima K, Okada T, Motoi F, Fujishima F, Ishida K, Unno M, Shimosegawa T
    • Journal Title

      Intern Med

      Volume: 53 Pages: 2589-2593

    • NAID

      130004713252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] 我が国の急性膵炎の予後2014

    • Author(s)
      菊田和宏、正宗淳、濱田晋、下瀬川徹
    • Journal Title

      膵臓

      Volume: 29 Pages: 151-156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] 慢性膵炎の膵内外分泌機能と臨床像-全国調査から2014

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Journal Title

      胆と膵

      Volume: 35 Pages: 343-347

    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] The usefulness of endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of pancreatic neuroendocrine tumors based on the World Health Organization classification2014

    • Author(s)
      Unno J, Kanno A, Masamune A, Kasajima A, Fujishima F, Ishida K, Hamada S, Kume K, Kikuta K, Hirota M, Motoi F, Unno M, Shimosegawa T
    • Journal Title

      Scand J Gastroenterol

      Volume: 49 Issue: 11 Pages: 1367-1374

    • DOI

      10.3109/00365521.2014.934909

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] 我が国の急性膵炎の予後:全国調査から2014

    • Author(s)
      菊田和宏、正宗淳、濱田晋、下瀬川徹
    • Journal Title

      膵臓

      Volume: 29

    • NAID

      130004496059

    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] The seventh nationwide epidemiological survey for chronic pancreatitis in Japan: clinical significance of smoking habit in Japanese patients2014

    • Author(s)
      Hirota M, Shimosegawa T, Masamune A, Kikuta K, Kume K, Hamada S, Kanno A, Kimura K, Tsuji I, Kuriyama S; Research Committee of Intractable Pancreatic Diseases
    • Journal Title

      Pancreatology

      Volume: 14 Issue: 6 Pages: 490-496

    • DOI

      10.1016/j.pan.2014.08.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] 膵星細胞と膵島細胞の相関2014

    • Author(s)
      菊田和宏、正宗淳、濱田晋、滝川哲也、中野絵里子、下瀬川徹、
    • Journal Title

      胆と膵

      Volume: 35 Pages: 339-342

    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] Inflammation and pancreatic cancer: disease promoter and new therapeutic target.2014

    • Author(s)
      Hamada S, Masamune A, Shimosegawa T.
    • Journal Title

      J Gastroenterol.

      Volume: 49 Issue: 4 Pages: 605-617

    • DOI

      10.1007/s00535-013-0915-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390194, KAKENHI-PROJECT-23591008
  • [Journal Article] 高齢者急性膵炎の臨床的特徴2014

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Journal Title

      消化器内科

      Volume: 58 Pages: 95-101

    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] Bismuth classification is associated with the requirement for multiple biliary drainage in preoperative patients with malignant perihilar biliary stricture2014

    • Author(s)
      Miura S, Kanno A, Masamune A, Hamada S, Takikawa T, Nakano E, Yoshida N, Hongo S, Kikuta K, Kume K, Hirota M, Yoshida H, Katayose Y, Unno M, Shimosegawa T
    • Journal Title

      Surg Endosc

      Volume: in press Issue: 7 Pages: 1862-1870

    • DOI

      10.1007/s00464-014-3878-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] 全国調査から見たアルコール性急性膵炎の疫学的特徴2014

    • Author(s)
      菊田和宏、正宗淳、粂潔、下瀬川徹
    • Journal Title

      アルコールと医学生物学

      Volume: 32

    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] CUB-domain containing protein 1 represses the epithelial phenotype of pancreatic cancer cells2014

    • Author(s)
      Miura S, Hamada S, Masamune A, Satoh K, Shimosegawa T
    • Journal Title

      Exp Cell Res

      Volume: 321(2) Issue: 2 Pages: 209-218

    • DOI

      10.1016/j.yexcr.2013.12.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390194, KAKENHI-PROJECT-23591008, KAKENHI-PROJECT-24591022
  • [Journal Article] Alteration of the microRNA expression profile during the activation of pancreatic stellate cells2014

    • Author(s)
      Masamune A, Nakano E, Hamada S, Takikawa T, Yoshida N, Shimosegawa T.
    • Journal Title

      Scand J Gastroenterol

      Volume: 49 Issue: 3 Pages: 323-331

    • DOI

      10.3109/00365521.2013.876447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] 慢性膵炎に伴う線維化機構2014

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Journal Title

      胆と膵

      Volume: 35 Pages: 1035-1039

    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] MiR-365 induces gemcitabine resistance in pancreatic cancer cells by targeting the adaptor protein SHC1 and pro-apoptotic regulator BAX2014

    • Author(s)
      Hamada S, Masamune A, Miura S, Satoh K, Shimosegawa T
    • Journal Title

      Cell Signal

      Volume: 26(2) Issue: 2 Pages: 179-185

    • DOI

      10.1016/j.cellsig.2013.11.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390194, KAKENHI-PROJECT-23591008, KAKENHI-PROJECT-24591022, KAKENHI-PROJECT-24790674, KAKENHI-PROJECT-25670591
  • [Journal Article] 慢性膵炎の膵内外分泌機能と臨床像 - 全国調査から2014

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Journal Title

      胆と膵

      Volume: 35 Pages: 343-347

    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] Nationwide epidemiological survey of acute pancreatitis in Japan2014

    • Author(s)
      Hamada S, Masamune A, Kikuta K, Hirota M, Tsuji I, Shimosegawa T; Research Committee of Intractable Diseases of the pancreas
    • Journal Title

      Pancreas

      Volume: 43 Issue: 8 Pages: 1244-1248

    • DOI

      10.1097/mpa.0000000000000200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] CONUTによる急性膵炎の栄養評価2013

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Journal Title

      消化と吸収

      Volume: 35 Pages: 193-196

    • NAID

      10031169262

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] Connexins Regulate Cell Functions in Pancreatic Stellate Cells.2013

    • Author(s)
      Masamune A, Suzuki N, Kikuta K, Ariga H, Hayashi S, Takikawa T, Kume K, Hamada S, Hirota M, Kanno A, Egawa S, Unno M, Shimosegawa T.
    • Journal Title

      Pancreas

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] The angiotensin II type I receptor blocker olmesartan inhibits the growth of pancreatic cancer by targeting stellate cell activities in mice.2013

    • Author(s)
      Masamune A, Hamada S, Kikuta K, Takikawa T, Miura S, Nakano E, Shimosegawa T.
    • Journal Title

      Scand J Gastroenterol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] miR-197 induces epithelialmesenchymal transition in pancreatic cancer cells by targeting p120 catenin. J Cell Physiol2013

    • Author(s)
      Hamada S, et al
    • Journal Title

      J Cell Physiol

      Volume: 228(6) Issue: 6 Pages: 1255-63

    • DOI

      10.1002/jcp.24280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390253, KAKENHI-PROJECT-23390194, KAKENHI-PROJECT-23591008, KAKENHI-PROJECT-24591003, KAKENHI-PROJECT-24591022, KAKENHI-PROJECT-24790674, KAKENHI-PROJECT-25461020
  • [Journal Article] Identification of novel missense CTRC variants in Japanese patients with chronic pancreatitis2013

    • Author(s)
      Masamune A, Nakano E, Kume K, Kakuta Y, Ariga H, Shimosegawa T
    • Journal Title

      Gut

      Volume: 62 Issue: 4 Pages: 653-654

    • DOI

      10.1136/gutjnl-2012-303860

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008, KAKENHI-PROJECT-23659392
  • [Journal Article] Transforming growth factor-α activates pancreatic stellate cells and may be involved in matrix metalloproteinase-1 upregulation2013

    • Author(s)
      Tahara H, Sato K, Yamazaki Y, Ohyama T, Horiguchi N, Hashizume H, Kakizaki S, Takagi H, Ozaki I, Arai H, Hirato J, Jesenofsky R, Masamune A, Mori M
    • Journal Title

      Lab Invest

      Volume: 93 Issue: 6 Pages: 720-732

    • DOI

      10.1038/labinvest.2013.59

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] Variants in CPA1 are strongly associated with early onset chronic pancreatitis2013

    • Author(s)
      Witt H, Beer S, Rosendahl J, Chen JM, Chandak GR, Masamune A, Bence M, Szmola R, Oracz G, Macek M Jr, Bhatia E, Steigenberger S, Lasher D, Bühler F, Delaporte C, Tebbing J, Ludwig M, Pilsak C, Saum K, Bugert P, Masson E, Paliwal S, Bhaskar S, Sobczynska-Tomaszewska A, Bak D, Balascak I, Choudhuri G, Nageshwar Reddy D, Rao GV, Thomas V, Kume K, Nakano E, Kakuta Y, Shimosegawa T, Durko L, Szabó A, Schnúr A, Hegyi P, Rakonczay Z Jr, Pfützer R, Schneider A, Groneberg DA, Braun M, Schmidt H, Witt U, Friess H, Algül H, Landt O, Schuelke M, Krüger R, Wiedenmann B, Schmidt F, Zimmer KP, Kovacs P, Stumvoll M, Blüher M, Müller T, Janecke A, Teich N, Grützmann R, Schulz HU, Mössner J, Keim V, Löhr M, Férec C, Sahin-Tóth M.
    • Journal Title

      Nature Genet

      Volume: 45 Issue: 10 Pages: 1216-1220

    • DOI

      10.1038/ng.2730

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] Pancreatic stellate cells reduce insulin expression and induce apoptosis in pancreatic β-cells2013

    • Author(s)
      Kikuta K, Masamune A, Hamada S, Takikawa T, Nakano E, Shimosegawa T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] miR-210 regulates the interaction between pancreatic cancer cells and stellate cells2013

    • Author(s)
      Takikawa T, Masamune A, Hamada S, Nakano E, Yoshida N, Shimosegawa T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 437 Issue: 3 Pages: 433-439

    • DOI

      10.1016/j.bbrc.2013.06.097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] Pancreatic stellate cells reduce insulin expression and induce apoptosis in pancreaticβ-cells2013

    • Author(s)
      Kikuta K, Masamune A, Hamada S, Takikawa T, Nakano E, Shimosegawa T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 433 Issue: 3 Pages: 292-7

    • DOI

      10.1016/j.bbrc.2013.02.095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008, KAKENHI-PROJECT-24591003
  • [Journal Article] Connexins regulate cell functions in pancreatic stellate cells2013

    • Author(s)
      Masamune A, Suzuki N, Kikuta K, Ariga H, Hayashi S, Takikawa T, Kume K, Hamada S, Hirota M, Kanno A, Egawa S, Unno M, Shimosegawa T.
    • Journal Title

      Pancreas

      Volume: 42 Issue: 2 Pages: 308-316

    • DOI

      10.1097/mpa.0b013e31825c51d6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] Alteration of pancreatic cancer cell functions by tumor-stromal cell interaction2013

    • Author(s)
      Hamada S, Masamune A, Shimosegawa T
    • Journal Title

      Front Physiol

      Volume: 4 Pages: 318-318

    • DOI

      10.3389/fphys.2013.00318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] Identification ofnovel missense CTRC variants in Japanese patients with chronic pancreatitis2013

    • Author(s)
      Masamune A, Nakano E, Kume K, Kakuta Y, Ariga H, Shimosegawa T
    • Journal Title

      Gut

      Volume: 62 Pages: 653-654

    • Data Source
      KAKENHI-PROJECT-23659392
  • [Journal Article] Novel therapeutic strategies targeting tumor-stromal interactions in pancreatic cancer2013

    • Author(s)
      Hamada S, Masamune A, Shimosegawa T
    • Journal Title

      Front Physiol

      Volume: 4 Pages: 331-331

    • DOI

      10.3389/fphys.2013.00331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] Pancreatic stellate cells - Multi-functional cells in the pancreas2013

    • Author(s)
      Masamune A, Shimosegawa T
    • Journal Title

      Pancreatology

      Volume: 13 Issue: 2 Pages: 102-105

    • DOI

      10.1016/j.pan.2012.12.058

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] The angiotensin II type I receptor blocker olmesartan inhibits the growth of pancreatic cancer by targeting stellate cell activities in mice2013

    • Author(s)
      Masamune A, Hamada S, Kikuta K, Takikawa T, Miura S, Nakano E, Shimosegawa T.
    • Journal Title

      Scand J Gastroenterol

      Volume: 48 Issue: 5 Pages: 602-609

    • DOI

      10.3109/00365521.2013.777776

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008, KAKENHI-PROJECT-24591003
  • [Journal Article] Pancreati duct drainage using EUS-guided rendezvous technique for stenotic pancreaticojejunostomy2013

    • Author(s)
      Takikawa T, Kanno A, Masamune A, Hamada S, Nakano E, Miura S, Ariga H, Unno J, Kume K, Kikuta K, Hirota M, Yoshida H, Katayose Y, Unno M, Shimosegawa T
    • Journal Title

      World J Gastroenterol

      Volume: 19 Issue: 31 Pages: 5182-5186

    • DOI

      10.3748/wjg.v19.i31.5182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003, KAKENHI-PROJECT-25461020
  • [Journal Article] PRSS1 c.623G>C (p.G208A) variant is associated with pancreatitis in Japan2013

    • Author(s)
      Masamune A, Nakano E, Kume K, Kakuta Y, Shimosegawa T
    • Journal Title

      Gut

      Volume: (In press) Issue: 2 Pages: 366-366

    • DOI

      10.1136/gutjnl-2013-304925

    • Data Source
      KAKENHI-PROJECT-23659392
  • [Journal Article] Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells2012

    • Author(s)
      Hamada S, Masamune A, Takikawa T, Suzuki N, Kikuta K, Hirota M, Hamada H, Kobune M, Satoh K, Shimosegawa T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 421(2) Issue: 2 Pages: 349-354

    • DOI

      10.1016/j.bbrc.2012.04.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390194, KAKENHI-PROJECT-23591008, KAKENHI-PROJECT-24591003
  • [Journal Article] 急性膵炎の成因と疫学2012

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Journal Title

      消化器外科

      Volume: 35 Pages: 1725-1730

    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] Regulators of epithelial mesenchymal transition in pancreatic cancer2012

    • Author(s)
      Hamada S, Satoh K, Masamune A, Shimosegawa T
    • Journal Title

      Front Physiol

      Volume: 3 Pages: 254-254

    • DOI

      10.3389/fphys.2012.00254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] Research Committee on Intractable Diseases of Pancreas. Nationwide epidemiological survey of autoimmune pancreatitis in Japan2012

    • Author(s)
      Kanno A, Nishimori I, Masamune A, Kikuta K, Hirota M, Kuriyama S, Tsuji I, Shimosegawa T
    • Journal Title

      Pancreas

      Volume: 41 Issue: 6 Pages: 835-9

    • DOI

      10.1097/mpa.0b013e3182480c99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23651022, KAKENHI-PROJECT-24591003
  • [Journal Article] Distinct clinical features of two patients that progressed from the early phase of chronic pancreatitis to the advanced phase.2012

    • Author(s)
      Hirota M, Shimosegawa T, Kanno A, Kikuta K, Kume K, Hamada S, Unno J, Masamune A.
    • Journal Title

      Tohoku J Exp Med

      Volume: 228 Pages: 173-180

    • NAID

      10031127345

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] StellaTUM : current consensus and discussion on pancreatic stellate cell research2012

    • Author(s)
      Erkan M, Adler G, Apte MV, Bachem MG, Buchholz M, Detlefsen S, Esposito I, Friess H, Gress TM, Habisch HJ, Hwang RF, Jaster R, Kleeff J, Klöppel G, Kordes C, Logsdon CD, Masamune A, Michalski CW, Oh J, Phillips PA, Pinzani M, Reiser-Erkan C, Tsukamoto H, Wilson J.
    • Journal Title

      Gut.

      Volume: 61 Issue: 2 Pages: 172-178

    • DOI

      10.1136/gutjnl-2011-301220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Journal Article] [Case report; Multiple gastrointestinal stromal tumors associated with neurofibromatosis type I preoperatively diagnosed by endoscopic ultrasound-guided fine-needle aspiration: report of a case and review of literature].2012

    • Author(s)
      Miura S, Kume K, Hamada S, Kanno A, Unno J, Kikuta K, Hirota M, Masamune A, Shimosegawa T.
    • Journal Title

      Nihon Naika Gakkai Zasshi

      Volume: 101 Pages: 3510-3512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] Early detection of low enhanced pancreatic parenchyma by contrast-enhanced computed tomography predicts poor prognosis of patients with acute pancreatitis.2012

    • Author(s)
      Hirota M, Satoh K, Kikuta K, Masamune A, Kume K, Hamada S, Satoh A, Kanno A, Unno J, Ito H, Ariga H, Shimosegawa T.
    • Journal Title

      Pancreas

      Volume: 41 Issue: 7 Pages: 1099-1104

    • DOI

      10.1097/mpa.0b013e318249a904

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] Diagnosis of autoimmune pancreatitis by EUS-FNA by using a 22-gauge needle based on the International Consensus Diagnostic Criteria.2012

    • Author(s)
      Kanno A, Ishida K, Hamada S, Fujishima F, Unno J, Kume K, Kikuta K, Hirota M, Masamune A, Satoh K, Notohara K, Shimosegawa T.
    • Journal Title

      Gastrointest Endosc

      Volume: 76 Issue: 3 Pages: 594-602

    • DOI

      10.1016/j.gie.2012.05.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] Do genetic variants in the SPINK1 gene affect the level of serum PSTI?2012

    • Author(s)
      Kume K, Masamune A, Ariga H, Hayashi S, Takikawa T, Miura S, Suzuki N, Kikuta K, Hamada S, Hirota M, Kanno A, Shimosegawa T.
    • Journal Title

      J Gastroenterol

      Volume: 47 Issue: 11 Pages: 1267-1274

    • DOI

      10.1007/s00535-012-0590-3

    • NAID

      10031126959

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Journal Article] MiR-126 acts as a tumor suppressor in pancreatic cancer cells via the regulation of ADAM92012

    • Author(s)
      Hamada S, Satoh K, Fujibuchi W, Hirota M, Kanno A, Unno J, Masamune A, Kikuta K, Kume K, Shimosegawa T
    • Journal Title

      Mol Cancer Res

      Volume: 10(1) Issue: 1 Pages: 3-10

    • DOI

      10.1158/1541-7786.mcr-11-0272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790626, KAKENHI-PROJECT-23390194
  • [Journal Article] Calcium-binding protein S100P is a novel diagnostic marker of cholangiocarcinoma.2011

    • Author(s)
      Hamada S, Satoh K, Hirota M, Kanno A, Ishida K, Umino J, Ito H, Kikuta K, Kume K, Masamune A, Katayose Y, Unno M, Shimosegawa T.
    • Journal Title

      Cancer Sci. 102

      Pages: 150-156

    • NAID

      10029288859

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Pancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling.2011

    • Author(s)
      Mantoni TS, Lunardi S, Al-Assar O, Masamune A, Brunner TB.
    • Journal Title

      Cancer Res. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Genetic background is different between sentinel and recurrent acute pancreatitis.2011

    • Author(s)
      Masamune A, Ariga H, Kume K, Kakuta Y, Satoh K, Satoh A, Shimosegawa T
    • Journal Title

      J Gastroenterol Hepatol. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Evaluation of MSX2 mRNA in brush cytology specimens distinguished pancreatic carcinoma from chronic pancreatitis.2011

    • Author(s)
      Satoh K, Hamada S, Kanno A, Ishida K, Ito H, Hirota M, Masamune A, Egawa S, Unno M, Shimosegawa T.
    • Journal Title

      Cancer Sci. 102

      Pages: 157-161

    • NAID

      10029288885

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Genetic background is different between sentinel and recurrent acutepancreatitis.2011

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Gastroenterol Hepatol

      Volume: Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Genetic background is different between sentinel and recurrent acute pancreatitis.2011

    • Author(s)
      Masamune A, Ariga H, Kume K, Kakuta Y, Satoh K, Satoh A, Shimosegawa T.
    • Journal Title

      J Gastroenterol Hepatol. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Genetic background is different between sentinel and recurrent acute pancreatitis.2011

    • Author(s)
      正宗 淳
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 26 Issue: 6 Pages: 729-738

    • DOI

      10.1111/j.1440-1746.2011.06691.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659392
  • [Journal Article] The homeobox gene MSX2 determines chemosensitivity of pancreatic cancer cells via the regulation of transporter gene ABCG2.2011

    • Author(s)
      Hamada S, Satoh K, Hirota M, Kanno A, Umino J, Ito H, Masamune A, Kikuta K, Kume K, Shimosegawa T.
    • Journal Title

      J Cell Physiol. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Genetic background is different between sentinel and recurrent acute pancreatitis.2011

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659185
  • [Journal Article] 急性膵炎・慢性膵炎に関連する遺伝子多型2011

    • Author(s)
      正宗 淳
    • Journal Title

      肝・胆・膵

      Volume: 62 Pages: 967-975

    • Data Source
      KAKENHI-PROJECT-23659392
  • [Journal Article] The evaluation of MSX2 mRNA expression level in biliary brush cytological specimens.2011

    • Author(s)
      Ito H, Satoh K, Hamada S, Hirota M, Kanno A, Ishida K, Unno J, Masamune A, Katayose Y, Unno M, Shimosegawa T.
    • Journal Title

      Anticancer Res. 31

      Pages: 1011-1017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Effects of ethanol and its metabolites on human pancreatic stellate cells.2010

    • Author(s)
      Masamune A, et al.
    • Journal Title

      Dig Dis Sci

      Volume: 55 Pages: 204-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] -651C/T promoter polymorphism in the CD14 gene is associated with severity of acute pancreatitis in Japan.2010

    • Author(s)
      Masamune A, Kume K, Kikuta K, Watanabe T, Hirota M, Satoh K, Kanno A, Suzuki N, Kakuta Y, Shimosegawa T
    • Journal Title

      J Gastroenterol. 45

      Pages: 225-233

    • NAID

      10027214689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells.2010

    • Author(s)
      Kikuta K, Masamune A, Watanabe T, Ariga H, Itoh H, Hamada S, Satoh K, Egawa S, Unno M, Shimosegawa T
    • Journal Title

      Biochem Biophys Res Commun. 403

      Pages: 380-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] -651C/T promoter polymorphism in the CD14 gene is associated with severity of acute pancreatitis in Japan.2010

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Gastroenterol

      Volume: 45 Pages: 225-233

    • NAID

      10027214689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659185
  • [Journal Article] Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells.2010

    • Author(s)
      Kikuta K, Masamune A, Watanabe T, Ariga H, Itoh H, Hamada S, Satoh K, Egawa S, Unno M, Shimosegawa T.
    • Journal Title

      Biochem Biophys Res Commun. 403

      Pages: 380-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Effects of ethanol and its metabolites on human pancreatic stellate cells.2010

    • Author(s)
      Masamune A, Satoh A, Watanabe T, Kikuta K, Satoh M, Suzuki N, Satoh K, Shimosegawa T
    • Journal Title

      Dig Dis Sci. 55

      Pages: 204-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Nuclear expression of interleukin-33 in pancreatic stellate cells.2010

    • Author(s)
      Masamune A, Watanabe T, Kikuta K, Satoh K, Kanno A, Shimosegawa T.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol. 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] -651C/T promoter polymorphism in the CD14 gene is associated with severity of acute pancreatitis in Japan2010

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Gastroenterol 45

      Pages: 225-233

    • NAID

      10027214689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659185
  • [Journal Article] Effects of ethanol and its metabolites on human pancreatic stellate cells.2010

    • Author(s)
      Masamune A, Satoh A, Watanabe T, Kikuta K, Satoh M, Suzuki N, Satoh K, Shimosegawa T.
    • Journal Title

      Dig Dis Sci. 55

      Pages: 204-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] -651C/T promoter polymorphism in the CD14 gene is associated with severity of acute pancreatitis in Japan.2010

    • Author(s)
      Masamune A, Kume K, Kikuta K, Watanabe T, Hirota M, Satoh K, Kanno A, Suzuki N, Kakuta Y, Shimosegawa T.
    • Journal Title

      J Gastroenterol. 45

      Pages: 225-233

    • NAID

      10027214689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Nuclear expression of interleukin-33 in pancreatic stellate cells.2010

    • Author(s)
      Masamune A, Watanabe T, Kikuta K, Satoh K, Kanno A, Shimosegawa T
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol. 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Nuclear expression of interleukin-33 in pancreatic stellate cells.2010

    • Author(s)
      Masamune A, et al.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] A loss-of-function p.G191R variant in the anionic trypsinogen (PRSS2) gene in Japanese patients with pancreatic disorders.2009

    • Author(s)
      Kume K, Masamune A, Takagi Y, Kikuta K, Watanabe T, Satoh K, Satoh A, Hirota M, Hamada S, Shimosegawa T
    • Journal Title

      Gut 58

      Pages: 820-824

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Bone marrow contributes to the population of pancreatic stellate cells in mice.2009

    • Author(s)
      Watanabe T, Masamune A, Kikuta K, Hirota M, Kume K, Satoh K, Shimosegawa T.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol. 297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis2009

    • Author(s)
      Masamune A, et al.
    • Journal Title

      Clin Gastroenterol Hepatol 11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] A loss-of-function p.G191R variant in the anionic trypsinogen (PRSS2) gene in Japanese patients with pancreatic disorders.2009

    • Author(s)
      Kume K, Masamune A, Takagi Y, Kikuta K, Watanabe T, Satoh K, Satoh A, Hirota M, Hamada S, Shimosegawa T.
    • Journal Title

      Gut 58

      Pages: 820-824

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Ellagic acid inhibits pancreatic fibrosis in male Wistar Bonn/Kobori rats.2009

    • Author(s)
      Suzuki N, Masamune A, Kikuta K, Watanabe T, Satoh K, Shimosegawa T
    • Journal Title

      Dig Dis Sci. 54

      Pages: 802-810

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Signal transduction in pancreatic stellate cells2009

    • Author(s)
      Masamune A, et.al.
    • Journal Title

      J Gastroentetol 44

      Pages: 249-260

    • NAID

      10025173977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Signal transduction in pancreatic stellate cells.2009

    • Author(s)
      正宗淳, 下瀬川徹
    • Journal Title

      J Gastroenterol. 44

      Pages: 249-260

    • NAID

      10025173977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis.2009

    • Author(s)
      Masamune A, Watanabe T, Kikuta K, Shimosegawa T
    • Journal Title

      Clin Gastroenterol Hepatol. 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Fibrinogen induces cytokine and collagen production in pancreatic stellate cells.2009

    • Author(s)
      Masamune A, Kikuta K, Watanabe T, Satoh K, Hirota M, Hamada S, Shimosegawa T
    • Journal Title

      Gut 58

      Pages: 550-559

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Fibrinogen induces cytokine and collagen production in pancreatic stellate cells.2009

    • Author(s)
      Masamune A, Kikuta K, Watanabe T, Satoh K, Hirota M, Hamada S, Shimosegawa T.
    • Journal Title

      Gut 58

      Pages: 550-559

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Effects of ethanol and its metabolites on human pancreatic stellate cells2009

    • Author(s)
      Masamune A, et.al.
    • Journal Title

      Dig Dis Sci (Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Signal transduction in pancreatic stellate cells.2009

    • Author(s)
      Masamune A, Shimosegawa T.
    • Journal Title

      J Gastroenterol. 44

      Pages: 249-260

    • NAID

      10025173977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis.2009

    • Author(s)
      Masamune A, Watanabe T, Kikuta K, Shimosegawa T.
    • Journal Title

      Clin Gastroenterol Hepatol. 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] LIV-1 enhances the aggressive phenotype through the induction of epithelial to mesenchymal transition in human pancreatic carcinoma cells.2009

    • Author(s)
      Unno J, Satoh K, Hirota M, Kanno A, Hamada S, Ito H, Masamune A, Tsukamoto N, Motoi F, Egawa S, Unno M, Horii A, Shimosegawa T.
    • Journal Title

      Int J Oncol. 35

      Pages: 813-821

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Signal transduction in pancreatic stellate cells.2009

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Gastroenterol 44

      Pages: 249-260

    • NAID

      10025173977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Bone marrow contributes to the population of pancreatic stellate cells in mice.2009

    • Author(s)
      Watanabe T, Masamune A, Kikuta K, Hirota M, Kume K, Satoh K, Shimosegawa T
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol. 297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Bone marrow contributes to the population of pancreatic stellate cells in mice.2009

    • Author(s)
      Watanabe T, Masamune A, et al.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Ellagic acid inhibits pancreatic fibrosis in male Wistar Bonn/Kobori rats.2009

    • Author(s)
      Suzuki N, Masamune A, Kikuta K, Watanabe T, Satoh K, Shimosegawa T.
    • Journal Title

      Dig Dis Sci. 54

      Pages: 802-810

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Fibrinogen induces cytokine and collagen production in pancrea tic stellate cells2009

    • Author(s)
      Masamune A, et.al.
    • Journal Title

      Gut 58

      Pages: 550-559

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Pancreatic stellate cells express Toll-like receptors2008

    • Author(s)
      Masamune A. Kikuta K, Watanabe T, Satoh K, Satoh A, Shimosegawa T.
    • Journal Title

      J Gastroenterol 43

    • NAID

      10021268622

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590712
  • [Journal Article] Pancreatic stellate cells express Toll-like receptors.2008

    • Author(s)
      Masamune A, et. al.
    • Journal Title

      J Gastroenterol 43(In press)

    • NAID

      10021268622

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590712
  • [Journal Article] NADPH oxidase plays a crucial role in the activation of pancreatic stellate Cells.2008

    • Author(s)
      Masamune A, et. al.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 294

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590712
  • [Journal Article] アルコールと膵炎-酒を飲みすぎると膵炎になるか2008

    • Author(s)
      正宗淳、下瀬川徹
    • Journal Title

      別刷医学のあゆみ-アルコール医学・医療の最前線

      Pages: 85-90

    • Data Source
      KAKENHI-PROJECT-20590802
  • [Journal Article] Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer2008

    • Author(s)
      Masamune A, et.al.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Stromal SPARC expression and patient survival after chemoradiation for non-resectable pancreatic adenocarcinoma.2008

    • Author(s)
      Mantoni TS, Schendel RR, Rodel F, Niedobitek G, Al-Assar O, Masamune A, Brunner TB.
    • Journal Title

      Cancer Biol Ther. 7

      Pages: 1806-1815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells2008

    • Author(s)
      Masamune A. Watanabe T, Kikuta K, Satoh K, Shimosegawa T.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 294

      Pages: 99-108

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590712
  • [Journal Article] NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells.2008

    • Author(s)
      Masamune A, et. al.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590712
  • [Journal Article] Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer.2008

    • Author(s)
      Masamune A, Kikuta K, Watanabe T, Satoh K, Hirota M, Shimosegawa T.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol. 295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Journal Article] Differential roles of the SPINK1 gene mutations in alcoholic and non-alcoholic chronic pancreatitis.2007

    • Author(s)
      Masamune A, et. al.
    • Journal Title

      J Gastroenterol S17

      Pages: 135-140

    • NAID

      10018540387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659180
  • [Journal Article] N34S mutation in the SPINK1 gene is not associated with alternative splicing.2007

    • Author(s)
      Masamune A, et. al.
    • Journal Title

      Pancreas 34

      Pages: 423-428

    • NAID

      10024366877

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659180
  • [Journal Article] Differential roles of the SPINK1 gene mutations in alcoholic and nonalcoholic chronic pancreatitis.2007

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Gastroenterol 42

      Pages: 135-140

    • NAID

      10018540387

    • Data Source
      KAKENHI-PROJECT-17659208
  • [Journal Article] Galectin-1 stimulates proliferation and chemokine production of pancreatic stellate cells.2006

    • Author(s)
      Masamune A, et al.
    • Journal Title

      AJP-Gastrointestinal and Liver Physiology 290・4

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Galectin-1 stimulates proliferation and chemokine production of pancreatic stellate cells.2006

    • Author(s)
      Masamune A, et al.
    • Journal Title

      AJP-Gastrointestinal and Liver Physiology Epub

    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Galectin-1 stimulates proliferation and chemokine production of pancreatic stellate cells.2006

    • Author(s)
      Masamune A, et al.
    • Journal Title

      AJP-Gastrointestinal and Liver Physiology 290(4)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Curcumin blocks activation of pancreatic stellate cells2006

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Cell Biochem 97(5)

      Pages: 1080-1080

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Curcumin blocks activation of pancreatic stellate cells2006

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Cell Biochem 97・5

      Pages: 1080-1080

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Curcumin blocks activation of pancreatic stellate cells.2006

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Cell Biochem 97・5

      Pages: 1080-93

    • Data Source
      KAKENHI-PROJECT-18590712
  • [Journal Article] Galectin-l induces chemokine production and proliferation in pancreatic stellate cells.2006

    • Author(s)
      Masamune A, et al.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol. 290・4

    • Data Source
      KAKENHI-PROJECT-18590712
  • [Journal Article] Endothelin-1 stimulates pancreatic stellate cell contraction and migration2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      World J Gastroenterol 11(39)

      Pages: 6144-6144

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Protease-activated receptor-2-mediated proliferation and collagen production of rat pancreatic stellate cells2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Pharmacol Exp Ther 312(2)

      Pages: 651-651

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Green tea polyphenol epigallocatechin-3-gallate blocks PDGF-induced proliferation and migration of pancreatic stellate cells.2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      World J Gastroenterol (In press)

    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Green tea polyphenol epigallocatechin-3-gallate blocks PDGF-induced proliferation and migration of pancreatic stellate cells2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      World J Gastroenterol 11

      Pages: 3368-3368

    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Activation of JAK-STAT pathway is required for platelet-derived growth factor-induced proliferation of pancreatic stellate cells.2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      World J Gastroenterol. (In press)

    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Protease-activated receptor-2-mediated proliferation and collagen production of rat pancreatic stellate cells2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Pharmacol Exp Ther 352

      Pages: 651-651

    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Endothelin-1 stimulates pancreatic stellate cell contraction and migration2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      World J Gastroenterol 11・39

      Pages: 6144-6144

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Curcumin blocks activation of pancreatic stellate cells2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Cell Biochem Epub

      Pages: 1080-1080

    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Endothelin-1 stimulates pancreatic stellate cell contraction and migration2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      World J Gastroenterol 11

      Pages: 6144-6144

    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Protease-activated receptor-2-mediated proliferation and collagen production of rat pancreatic stellate cells2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Pharmacol Exp Ther 312・2

      Pages: 651-651

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Protease-activated receptor-2-mediated proliferation and collagen production of rat pancreatic stellate cells.2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Pharmacol Exp Ther 352

      Pages: 651-658

    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Ellagic acid blocks activation of pancreatic stellate cells2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      Biochem Pharmacol 70

      Pages: 869-869

    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Ellagic acid blocks activation of pancreatic stellate cells2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      Biochem Pharmacol 70・6

      Pages: 869-869

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Ellagic acid blocks activation of pancreatic stellate cells.2005

    • Author(s)
      Masamune A, et al.
    • Journal Title

      Biochem Pharmacol 70(6)

      Pages: 869-869

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] 4-Hydroxy-2,3-nonenal activates activator protein-1 and MAP kinases in rat pancreatic stellate cells.2004

    • Author(s)
      Kikuta K, Masamune A, et al.
    • Journal Title

      World J Gastroenterol 10

      Pages: 2344-2351

    • Data Source
      KAKENHI-PROJECT-16590572
  • [Journal Article] Inhibition of c-Jun N-terminal kinase blocked the activation of rat pancreatic2004

    • Author(s)
      Masamune A, et al.
    • Journal Title

      J Pharmacol Exp Ther 310

      Pages: 520-527

    • Data Source
      KAKENHI-PROJECT-16590572
  • [Presentation] 慢性膵炎における生活習慣改善の意向と生活習慣の実態2023

    • Author(s)
      菊田和宏、松本諒太郎、滝川哲也、濱田晋、正宗淳
    • Organizer
      第40回日本胆膵病態・生理研究会
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] 慢性膵炎における飲酒量と生活習慣の関連に関する検討2023

    • Author(s)
      菊田和宏、松本諒太郎、滝川哲也、正宗淳
    • Organizer
      第42回アルコール医学生物学研究会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] 慢性膵炎患者における食習慣の検討2023

    • Author(s)
      菊田和宏、松本諒太郎、滝川哲也、濱田晋、正宗淳
    • Organizer
      第54回日本消化吸収学会総会
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] 遺伝子型による慢性膵炎臨床像の検討2022

    • Author(s)
      佐々木 滉, 菊田 和宏, 正宗 淳
    • Organizer
      第108回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] 慢性膵炎におけるサルコペニアの臨床的特徴2022

    • Author(s)
      松本諒太郎、菊田和宏、正宗淳
    • Organizer
      第30回日本消化器関連学会週間
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] Assessment of nutrient intake using BDHQ in patients with chronic pancreatitis2022

    • Author(s)
      Kazuhiro Kikuta, Ryotaro Matsumoto, Akira Sasaki, Fumiya Kataoka, Takanori Sano, Mio Ikeda, Tetsuya Takikawa, Shin Miura, Shin Hamada, Kiyoshi Kume, Atsushi Masamune
    • Organizer
      第53回日本膵臓学会大会・第26回国際膵臓学会
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] 慢性膵炎における簡易型自記式食事歴法質問票の有用性の検討2022

    • Author(s)
      菊田和宏, 松本諒太郎, 滝川哲也, 濱田晋, 正宗淳
    • Organizer
      第53回日本消化吸収学会総会
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] 慢性膵炎患者の脂質摂取状況に関する検討2022

    • Author(s)
      菊田和宏、松本諒太郎、佐々木滉、片岡史弥、佐野貴紀、池田未緒、田中裕、吉田直樹、滝川哲也、三浦晋、濱田晋、粂潔、正宗淳
    • Organizer
      第108回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] 高齢者慢性膵炎における疼痛管理の実態2021

    • Author(s)
      菊田和宏、濱田晋、正宗淳
    • Organizer
      第38回日本胆膵病態・生理研究会
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] 全国調査からみた慢性膵炎における膵内外分泌機能と臨床像の相関2021

    • Author(s)
      菊田和宏、濱田晋、正宗淳
    • Organizer
      第107回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] 慢性膵炎患者における筋肉量と身体活動量、栄養摂取量の関連2021

    • Author(s)
      菊田和宏、松本諒太郎、正宗淳
    • Organizer
      第29回日本消化器関連学会週間
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] 全国調査から見たアルコール性慢性膵炎における断酒指導と喫煙状況、併存疾患の現況2021

    • Author(s)
      菊田和宏、濱田晋、正宗淳
    • Organizer
      第52回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] アルコール性慢性膵炎における飲酒・喫煙と併存疾患の現況2021

    • Author(s)
      菊田和宏、正宗淳
    • Organizer
      第41回アルコール医学生物学研究会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07930
  • [Presentation] 全国調査からみた急性膵炎後の被包化壊死の現況2021

    • Author(s)
      菊田和宏、濱田晋、正宗淳
    • Organizer
      第57回日本腹部救急医学会総会
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] 全国調査から見た早期慢性膵炎診断の現況2021

    • Author(s)
      菊田和宏、岡崎和一、正宗淳
    • Organizer
      第51回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] Heterotypic 3D Culture Model of the Pancreatic Cancer Microenvironment with a Tunable Proportion of Fibrotic Elements2020

    • Author(s)
      田中啓祥,正宗 淳,狩野光伸
    • Organizer
      第79回日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02797
  • [Presentation] 全国調査からみた高齢者慢性膵炎における疼痛管理の現況2020

    • Author(s)
      菊田和宏、岡崎和一、正宗淳
    • Organizer
      JDDW2020
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] 全国調査からみた自己免疫性膵炎の現状2020

    • Author(s)
      菊田和宏、岡崎和一、正宗淳
    • Organizer
      第106回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] 全国調査からみた慢性膵炎の現状2020

    • Author(s)
      菊田和宏、岡崎和一、正宗淳
    • Organizer
      第106回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] 膵癌患者における栄養学的指標とサルコペニアに関する検討2020

    • Author(s)
      菊田和宏、濱田晋、正宗淳
    • Organizer
      第51回日本消化吸収学会総会
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] 慢性膵炎患者の社会復帰に関連する因子の検討2019

    • Author(s)
      菊田和宏、濱田晋、正宗淳
    • Organizer
      第50回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] 早期慢性膵炎の前向き予後調査2019

    • Author(s)
      菊田和宏、鍋島立秀、正宗淳
    • Organizer
      第50回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] The Revised Japanese Clinical Diagnostic Criteria for Chronic Pancreatitis2019

    • Author(s)
      Kikuta K, Masamune A
    • Organizer
      APA/JPS 50th Anniversary Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] 当科における膵石症治療の現状と課題2019

    • Author(s)
      菊田和宏、菅野敦、正宗淳
    • Organizer
      第97回 日本消化器内視鏡学会総会
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] 経過観察中の膵石症における糖尿病の現況2019

    • Author(s)
      菊田和宏、菅野敦、粂潔、濱田晋、三浦晋、滝川哲也、本郷星仁、鍋島立秀、田中裕、松本諒太郎、正宗淳
    • Organizer
      第105回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] 保存的に経過観察を行なっている膵石症における糖尿病の現況2018

    • Author(s)
      菊田和宏、菅野敦、粂潔、濱田晋、三浦晋、 滝川哲也、本郷星仁、鍋島立秀、正宗淳
    • Organizer
      第49回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-18K07960
  • [Presentation] Simultaneous activation of K-ras and Nrf2 induce pancreatic atrophy2017

    • Author(s)
      Hamada Shin, Masamune Atsushi, Taguchi Keiko, Yamamoto Masayuki and Shimosegawa Tooru
    • Organizer
      Digestive Disease Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04804
  • [Presentation] Nrf2 knockout suppresses pancreatic carcinogenesis in a mouse model2017

    • Author(s)
      Shin Hamada, Atsushi Masamune, Keiko Taguchi, Masayuki Yamamoto, Tooru Shimosegawa
    • Organizer
      Digestive Disease Week
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2017-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293171
  • [Presentation] Nrf2 knockout suppresses pancreatic carcinogenesis in a mouse model2017

    • Author(s)
      Shin Hamada, Atsushi Masamune, Keiko Taguchi, Masayuki Yamamoto, Tooru Shimosegawa
    • Organizer
      Digestive Disease Week
    • Place of Presentation
      San Diego (USA)
    • Year and Date
      2017-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461029
  • [Presentation] Nrf2 knockout suppresses pancreatic carcinogenesis in a mouse model2017

    • Author(s)
      Shin Hamada, Atsushi Masamune, Keiko Taguchi, Masayuki Yamamoto, Tooru Shimosegawa
    • Organizer
      Digestive Disease Week
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2017-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04804
  • [Presentation] Pancreatic stellate cells and cancer -Why targets stroma ?-2015

    • Author(s)
      Masamune A
    • Organizer
      The 10th International Symposium on Alcoholic liver and Pancreatic Diseases and Cirrhosis (ISALPD/C)
    • Place of Presentation
      Sao Paulo, Brazil
    • Year and Date
      2015-09-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04804
  • [Presentation] Pancreatic cancer and stellate cells -Role of exosomes in the interaction-2015

    • Author(s)
      Masamune A
    • Organizer
      Satellite Symposium on Alcoholism, ASH, NASH, and Pancreatitis
    • Place of Presentation
      Santiago, Chile
    • Year and Date
      2015-09-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04804
  • [Presentation] The nutritional index 'CONUT' is useful for predicting prognosis of acute pancreatitis2013

    • Author(s)
      Kazuhiro Kikuta, Atsushi Masamune, Tooru Shimosegawa
    • Organizer
      米国Digestive Disease Week 2013
    • Place of Presentation
      Orlando, USA
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] CUB-domain containing protein-1 is a novel marker of epithelial-mesenchymal transition2013

    • Author(s)
      Miura S, HamadaS, Masamune A, Shimosegawa T.
    • Organizer
      DDW2013
    • Place of Presentation
      Orland, FL, USA
    • Data Source
      KAKENHI-PROJECT-23390194
  • [Presentation] 全国調査からみた急性膵炎における耐糖能障害2013

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Organizer
      Japan Digestive Disease Week 2013
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] MiR-365 indirectly regulates drug resistance-related molecule Aryl hydrocarbon receptor nuclear translocator expression in pancreatic ductal adenocarcinoma cells.2013

    • Author(s)
      Hamada S, Satoh K, Masamune A, Kanno A, Kikuta K, Kume K, Unno J, Hirota M and Shimosegawa T.
    • Organizer
      DDW2013
    • Place of Presentation
      Orland, FL, USA
    • Data Source
      KAKENHI-PROJECT-23390194
  • [Presentation] 全国調査に基づく慢性膵炎の膵内外分泌機能と臨床像の解析2013

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Organizer
      第44回日本膵臓学会大会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] Pancreatic stellate cells induce β-cell dysfunction and apoptosis; a novel mechanism of diabetes in diseased pancreas-2013

    • Author(s)
      Masamune A, Kikuta K, Hamada S, Nakano E, Shimosegawa T
    • Organizer
      Digestive Disease Week 2013, the American Gastroenterological Association
    • Place of Presentation
      Orlando, FL, USA
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] Pancreatic stellate cells -multi-function cells in the pancreas-2013

    • Author(s)
      Masamune A.
    • Organizer
      17th International Symposium on the Cells of the Hepatic Sinusoid
    • Place of Presentation
      大阪
    • Year and Date
      2013-09-24
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] Role of microRNAs in the interactions between pancreatic stellate cells2013

    • Author(s)
      Takikawa T, Masamune A, Hamada S, Nakano E, Shimosegawa T
    • Organizer
      Digestive Disease Week 2013, the American Gastroenterological Association
    • Place of Presentation
      Orlando, FL, USA
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] Identification of inflammatory signal-stimulating microRNA in pancreatic duct cell carcinoma2013

    • Author(s)
      Hamada S, Satoh K, Masamune A, and Shimosegawa T
    • Organizer
      JSGE-ITC 2013
    • Place of Presentation
      鹿児島
    • Year and Date
      2013-03-23
    • Data Source
      KAKENHI-PROJECT-23390194
  • [Presentation] Prognosis of acute pancreatitis in Japan based on nationwide survey2013

    • Author(s)
      Kazuhiro Kikuta, Atsushi Masamune, Tooru Shimosegawa
    • Organizer
      第44回日本膵臓学会大会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] 次世代シークエンサーを用いた新たな膵炎関連遺伝子CTRC遺伝子変異全症例アルコール性非アルコール性健常対照群の同定2013

    • Author(s)
      粂潔、正宗淳、下瀬川徹
    • Organizer
      第99回日本消化器病学会総会
    • Place of Presentation
      鹿児島
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PROJECT-23659392
  • [Presentation] 浸潤性膵癌特異的oncomiR であるmiR-197 はVDAC1 発現を制御し好気的解糖を促進する2013

    • Author(s)
      濱田晋, 佐藤賢一, 正宗淳, 菅野敦, 菊田和宏, 粂潔, 廣田衛久, 下瀬川徹
    • Organizer
      第44回膵臓学会大会
    • Place of Presentation
      仙台
    • Year and Date
      2013-07-25
    • Data Source
      KAKENHI-PROJECT-23390194
  • [Presentation] ビタミンDは膵星細胞をターゲットとして膵線維化を抑制する2013

    • Author(s)
      正宗淳,下瀬川徹
    • Organizer
      第21回日本消化器関連学会週間
    • Place of Presentation
      東京
    • Year and Date
      2013-10-11
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] Pancreatic stellate cells induceβ-cell dysfunction and apoptosis–a novel mechanism of diabetes in diseased pancreas-2013

    • Author(s)
      Masamune A, Kikuta K, Hamada S, Nakano E, Shimosegawa T.
    • Organizer
      Digestive Disease Week 2013, the American Gastroenterological Association
    • Place of Presentation
      アメリカ合衆国オーランド
    • Year and Date
      2013-05-19
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] Pancreatic stellate cell contributes to the maintenance of cancer stem cell-like phenotype in pancreatic cancer cells2013

    • Author(s)
      Hamada S, Masamune A, Satoh K, Shimosegawa T
    • Organizer
      国際膵臓フォーラム2013
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] 全国調査から見た アルコール性急性膵炎の疫学的特徴2013

    • Author(s)
      菊田和宏、正宗淳、粂潔、下瀬川徹
    • Organizer
      第32回アルコール医学生物学研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] “Fibrosis in Extrahepatic Organ” : Pancreas2013

    • Author(s)
      Masamune A
    • Organizer
      17th International Symposium on the Cells of the Hepatic Sinusoid
    • Place of Presentation
      Osaka, Japan
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] 高齢者急性膵炎の疫学的検討2013

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Organizer
      第99回日本消化器病学会総会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] Identification of invasion-related microRNAs in pancreatic cancer by comprehensive analysis2012

    • Author(s)
      Hamada S, Satoh K, Hirota M, Kanno A, Masamune A, Kikuta K, Kume K, Unno J and Shimosegawa T
    • Organizer
      UEGW 2012 Amsterdam
    • Year and Date
      2012-10-23
    • Data Source
      KAKENHI-PROJECT-23390194
  • [Presentation] 次世代シークエンサーを用いた新たな膵炎関連遺伝子の同定2012

    • Author(s)
      粂潔、正宗淳、下瀬川徹
    • Organizer
      第20回浜名湖シンポジウム
    • Place of Presentation
      浜松
    • Year and Date
      2012-12-22
    • Data Source
      KAKENHI-PROJECT-23659392
  • [Presentation] miR-197は膵癌細胞のEMT誘導因子であり、p120 catenin発現を制御する2012

    • Author(s)
      濱田晋 佐藤賢一 三浦晋 廣田衛久 菅野敦 正宗淳 菊田和宏 粂潔 海野純 江川新一 元井冬彦 海野倫明 下瀬川徹
    • Organizer
      JDDW 2012
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23390194
  • [Presentation] miR-197 は膵癌細胞のEMT 誘導因子であり2012

    • Author(s)
      濱田晋, 佐藤賢一, 三浦晋, 廣田衛久, 菅野敦, 正宗淳, 菊田和宏, 粂潔, 海野純, 江川新一, 元井冬彦, 海野倫明, 下瀬川徹
    • Organizer
      p120 catenin 発現を制御するJDDW 2012
    • Place of Presentation
      神戸
    • Year and Date
      2012-10-10
    • Data Source
      KAKENHI-PROJECT-23390194
  • [Presentation] MicroRNA profiles are altered during the activation in pancreatic stellate cells2012

    • Author(s)
      Masamune A, Suzuki N, Kikuta K, Takikawa T, Ariga H, Shimosegawa T
    • Organizer
      Digestive Diseases Week 2012
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] Identification of invasion-related microRNAs in pancreatic cancer by comprehensive analysis.2012

    • Author(s)
      Shin Hamada, Kennichi Satoh, Morihisa Hirota, Atsushi Kanno, Atsushi Masamune, Kazuhiro Kikuta, Kiyoshi Kume, Jun Unno and Tooru Shimosegawa.
    • Organizer
      UEGW 2012
    • Place of Presentation
      Amsterdam、オランダ
    • Data Source
      KAKENHI-PROJECT-23390194
  • [Presentation] 膵星細胞は膵癌細胞の癌幹細胞様形質を増強する2012

    • Author(s)
      滝川哲也,正宗淳,濱田晋,海野純,鈴木範明,粂潔,菊田和宏,菅野敦,廣田衛久,佐藤賢一,下瀬川徹
    • Organizer
      第20回日本消化器関連学会週間
    • Place of Presentation
      神戸
    • Year and Date
      2012-10-11
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] Geographical differences in the genetics ofpancreatitis2012

    • Author(s)
      Masamune A, Shimosegawa T
    • Organizer
      7th International Symposium on Inherited Diseases of the Pancreas
    • Place of Presentation
      Prague, Czech Republic
    • Year and Date
      2012-06-23
    • Data Source
      KAKENHI-PROJECT-23659392
  • [Presentation] Geographical differences in the genetics of pancreatitis2012

    • Author(s)
      Masamune A
    • Organizer
      7th International Symposium on Inherited Diseases of the Pancreas
    • Place of Presentation
      Prague, Czech Republic
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659392
  • [Presentation] Pancreatic stellate cells -Multi-functional cells in the pancreas-. American Pancreatic Association/International Pancreatic Association2012

    • Author(s)
      Masamune A.
    • Organizer
      2012 Joint Meeting
    • Place of Presentation
      アメリカ合衆国マイアミ
    • Year and Date
      2012-11-01
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] CONUTによる急性膵炎の栄養評価2012

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Organizer
      第54回日本消化器病学会大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] 膵星細胞活性化に伴い広範なmicroRNA発現プロファイルの変化がおこる2012

    • Author(s)
      正宗 淳、下瀬川徹
    • Organizer
      第98回日本消化器病学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] Pancreatic Stellate Cells Express Inducible Nitric Oxide Synthase2012

    • Author(s)
      Suzuki N, Masamune A, Kikuta K, Takikawa T, Hayashi S, Shimosegawa T.
    • Organizer
      2012 Annual Meeting of the American Gastroenterological Association
    • Place of Presentation
      アメリカ合衆国サンディエゴ
    • Year and Date
      2012-05-20
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] 全国調査をもとにした 急性膵炎の成因と病態、予後に関する疫学的検討2012

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Organizer
      第43回日本膵臓学会大会
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] Pancreatic stellate cells -Multifunctional cells in the pancreas-2012

    • Author(s)
      Masamune A, Shimosegawa T
    • Organizer
      2012 Annual meeting of the American Pancreatic Association/International Pancreatic Association
    • Place of Presentation
      Miami, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] MicroRNA Profiles Are Altered During the Activation in Pancreatic Stellate Cells2012

    • Author(s)
      Masamune A, Suzuki S, Kikuta K, Takikawa T, Hayashi S, Ariga H, Shimosegawa T.
    • Organizer
      2012 Annual Meeting of the American Gastroenterological Association
    • Place of Presentation
      アメリカ合衆国サンディエゴ
    • Year and Date
      2012-05-20
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] 膵星細胞はbeta1-integrinシグナル系を介して膵癌細胞の放射線感受性を減弱させる.2011

    • Author(s)
      正宗 淳、下瀬川徹
    • Organizer
      J-DDW
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23591008
  • [Presentation] Hedgehog signaling pathway mediates activation of pancreatic stellate cells2010

    • Author(s)
      Masamune A, et al.
    • Organizer
      United European Gastroenterology Week
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-10-26
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Presentation] Hedgehog signaling pathway mediates activation of pancreatic stellate cells.2010

    • Author(s)
      正宗淳, 菊田和宏, 渡辺崇, 下瀬川徹
    • Organizer
      United European Gastroenterology Week.
    • Place of Presentation
      Barcelona, Spain.
    • Year and Date
      2010-10-26
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Presentation] Hedgehog signaling pathway mediates activation of pancreatic stellate cells.2010

    • Author(s)
      正宗淳, 菊田和宏, 渡辺崇, 下瀬川徹
    • Organizer
      United European Gastroenterology Week.
    • Place of Presentation
      Barcelona, Spain.
    • Year and Date
      2010-10-26
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Presentation] Advanced glycation end-productsは膵星細胞の増殖を促進する2009

    • Author(s)
      菊田和宏、正宗淳、渡辺崇、下瀬川徹
    • Organizer
      第40回日本消化器病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-31
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Presentation] Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis.2009

    • Author(s)
      Masamune A, et al.
    • Organizer
      Joint meeting of American Pancreatic Association & Japan Pancreas Society
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2009-11-05
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Presentation] Roles of pancreatic stellate cells in pancreatic fibrosis and inflammation.2009

    • Author(s)
      正宗淳, 下瀬川徹
    • Organizer
      AGA-JSGE Joint Meeting.
    • Place of Presentation
      Sapporo.
    • Year and Date
      2009-05-07
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Presentation] Toll-like receptor/CD14遺伝子多型は急性膵炎の重症化に関連する2009

    • Author(s)
      正宗淳、下瀬川徹
    • Organizer
      DDW-Japan 2009
    • Place of Presentation
      京都
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Presentation] Advanced glycation end-productsは膵星細胞の増殖とMCP-1産生を誘導する2009

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Organizer
      第95回日本消化器病学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2009-05-07
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Presentation] 膵線維化の分子機序-最新の知見-2009

    • Author(s)
      正宗淳
    • Organizer
      第4回新都心消化器カンファレンス
    • Place of Presentation
      東京
    • Year and Date
      2009-04-07
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Presentation] Toll-like receptor/CD14遺伝子多型は急性膵炎の重症化に関連する2009

    • Author(s)
      正宗淳、下瀬川徹
    • Organizer
      DDW-Japan 2009
    • Place of Presentation
      京都
    • Year and Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-21659185
  • [Presentation] Advanced glycation end-productsは膵星細胞の増殖とMCP-1産生を誘導する2009

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Organizer
      第95回日本消化器病学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2009-05-07
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Presentation] 膵線維化の分子機序-最新の知見-2009

    • Author(s)
      正宗淳
    • Organizer
      第4回新都心消化器カンファレンス
    • Place of Presentation
      東京
    • Year and Date
      2009-04-07
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Presentation] Advanced glycation end-productsは膵星細胞の増殖を促進する2009

    • Author(s)
      菊田和宏、正宗淳、渡辺崇、下瀬川徹
    • Organizer
      第40回日本消化器病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-31
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Presentation] Roles of pancreatic stellate cells in pancreatic fibrosis and inflammation.2009

    • Author(s)
      正宗淳, 下瀬川徹
    • Organizer
      AGA-JSGE Joint Meeting.
    • Place of Presentation
      Sapporo.
    • Year and Date
      2009-05-07
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Presentation] 膵星細胞からみた膵線維化の分子機序2008

    • Author(s)
      正宗淳
    • Organizer
      DDW-Japan 2008
    • Place of Presentation
      東京
    • Year and Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Presentation] フィブリノゲンはヒト膵星細胞におけるサイトカインとコラーゲン産生を誘導する2008

    • Author(s)
      正宗淳、菊田和宏、渡辺崇、佐藤賢一、下瀬川徹
    • Organizer
      DDW-Japan 2008
    • Place of Presentation
      東京
    • Year and Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Presentation] フィブリノゲンはヒト膵星細胞におけるサイトカインとコラーゲン産生を誘導する2008

    • Author(s)
      正宗淳、菊田和宏、渡辺崇、佐藤賢一、下瀬川徹
    • Organizer
      DDW-Japan 2008
    • Place of Presentation
      東京
    • Year and Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Presentation] フィブリノゲンはヒト膵星細胞のサイトカイン産生とコラーゲン産生を刺激する2008

    • Author(s)
      正宗淳, ほか
    • Organizer
      J-DDW
    • Place of Presentation
      東京
    • Year and Date
      2008-10-02
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Presentation] 膵炎関連遺伝子変異であるSPINK1遺伝子変異は膵癌の危険因子か2008

    • Author(s)
      粂潔、正宗淳、下瀬川徹
    • Organizer
      DDW-Japan 2008
    • Place of Presentation
      東京
    • Year and Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-20590802
  • [Presentation] 膵星細胞からみた膵線維化の分子機序2008

    • Author(s)
      正宗淳
    • Organizer
      DDW-Japan 2008
    • Place of Presentation
      東京
    • Year and Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-20590803
  • [Presentation] Hypoxia induces Collagen production in pancreatic stellate cells2007

    • Author(s)
      Masamune A, Kikuta K. Watanabe T, Shimosegawa T
    • Organizer
      Digestive Disease Week 2007
    • Place of Presentation
      Washington, DC. USA
    • Year and Date
      2007-05-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590712
  • [Presentation] Hypoxia induces collagen production in pancreatic stellate cells.2007

    • Author(s)
      Masamune A, et. al.
    • Organizer
      Digestive Diseases Week
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2007-05-18
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590712
  • [Presentation] 内視鏡下経胃的ネクロセクトミーが有効であった感染性膵壊死の1例

    • Author(s)
      竹内智、菊田和宏、粂潔、菅野敦、中野絵里子、有賀啓之、濱田晋、廣田衛久、正宗淳、下瀬川徹
    • Organizer
      第111回日本内科学会総会
    • Place of Presentation
      東京国際フォーラム (東京)
    • Year and Date
      2014-04-11 – 2014-04-12
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] The impact of diabetes mellitus on clinical outcome of acute pancreatitis in Japan

    • Author(s)
      Kazuhiro Kikuta, Atsushi Masamune, Shin Hamada, Tooru Shimosegawa
    • Organizer
      APA/JPS 45th anniversary meeting
    • Place of Presentation
      Hawaii (USA)
    • Year and Date
      2014-11-05 – 2014-11-09
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] 全国調査からみた急性膵炎における生活習慣病

    • Author(s)
      菊田和宏、正宗淳、下瀬川徹
    • Organizer
      第100回日本消化器病学会総会
    • Place of Presentation
      東京国際フォーラム (東京)
    • Year and Date
      2014-04-23 – 2014-04-24
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] The MiR-365 Increases Gemcitabine Resistance by Regulating Cell Cycle and Apoptosis-related Molecules

    • Author(s)
      Shin Hamada, Atsushi Masamune and Tooru Shimosegawa
    • Organizer
      45th Anniversary Meeting of APA/JPS
    • Place of Presentation
      Kohala coast, HI, USA
    • Year and Date
      2014-11-05 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-26461029
  • [Presentation] miR-197による癌細胞特異的代謝機構の制御

    • Author(s)
      濱田晋 正宗淳 下瀬川徹
    • Organizer
      JDDW2014
    • Place of Presentation
      神戸 神戸国際会議場
    • Year and Date
      2014-10-23 – 2014-10-26
    • Data Source
      KAKENHI-PROJECT-26461029
  • [Presentation] 全国調査から見た慢性膵炎患者における栄養状態の実態

    • Author(s)
      菊田和宏、正宗淳、廣田衛久、下瀬川徹
    • Organizer
      第45回日本膵臓学会大会
    • Place of Presentation
      北九州国際会議場 (小倉)
    • Year and Date
      2014-07-11 – 2014-07-12
    • Data Source
      KAKENHI-PROJECT-24591003
  • [Presentation] 急性膵炎発症早期の造影CTによる膵壊死予測診断能

    • Author(s)
      菊田和宏、正宗淳、濱田晋、廣田衛久、下瀬川徹
    • Organizer
      第56回日本消化器病学会大会
    • Place of Presentation
      神戸国際展示場・ポートピアホテル・神戸国際会議場 (神戸)
    • Year and Date
      2014-10-23 – 2014-10-26
    • Data Source
      KAKENHI-PROJECT-24591003
  • 1.  HAMADA Shin (20451560)
    # of Collaborated Projects: 16 results
    # of Collaborated Products: 65 results
  • 2.  SHIMOSEGAWA Tooru (90226275)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 21 results
  • 3.  KUME Kiyoshi (30431563)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 10 results
  • 4.  SATOH Kennichi (10282055)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 28 results
  • 5.  Mitsunobu Kano (80447383)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 6.  KIKUTA Kazuhiro (80420024)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 67 results
  • 7.  田口 恵子 (20466527)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 8.  SATOH Akihiko (70312569)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 9.  木村 憲治 (90359513)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  児玉 裕三 (80378687)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  長船 健二 (80502947)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  古本 祥三 (00375198)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  赤池 孝章 (20231798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  田中 啓祥 (20781941)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 15.  松本 諒太郎 (40963830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  山本 雅之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 17.  栗山 進一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  たら澤 邦男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  藤森 研司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  西原 広史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  松崎 典弥
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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