TOKUYAMA tsutomu 徳山勤

… Alternative Names

TOKUYAMA Tsutomu 徳山勤

Less

Researcher Number	90313957
Affiliation (based on the past Project Information) *help	2011 – 2018: 浜松医科大学, 医学部附属病院, 講師 2008: 浜松医科大学, 医学部・附属病院, 講師 2008: 浜松医科大学, 医学部附属病院, 講師 2007: 浜松医科大学, 医学部付属病院, 助教 2006: Hamamatsu University School of Medicine, University Hospital, Associate Professor, 医学部附属病院, 講師 … More 2001 – 2005: 浜松医科大学, 医学部附属病院, 助手 2004: Hamamatsu University School of Medicine, Neurosurgery, Assistant, 医学部附属病院, 助手 2002: 浜松医科大学, 医学部付属病院, 助手 Less
Review Section/Research Field	Principal Investigator Cerebral neurosurgery Except Principal Investigator Neurosurgery / Cerebral neurosurgery / Thoracic surgery / Cerebral neurosurgery
Keywords	Principal Investigator 移動能 / 悪性グリオーマ / 人工多能性幹細胞 Except Principal Investigator medulloblastoma / DNA microarray / developmentally regulated gene / oncogenesis / glioma / bystander effect / ganciclovir … More / gene therapy / 悪性転化 / グリオブラストーマ / 低悪性度グリオーマ / semi-quantitative RT-PCT / stem cell / oncogene / molecular mechanisms / siRNA / cancer stem cell / proliferation / differentiation / biological property / developmentally regulated / 定量的RT-PCR / 幹細胞 / 発生関連遺伝子 / 癌遺伝子 / 腫瘍形成機構 / 髄芽腫 / paraplegia model of rat / spinal reproduction / neuronal stem cell implantation / ischemic spinal cord injury / 脊髄虚血 / ラット対麻痺モデル / 神経再生治療 / 神経幹細胞移植 / 虚血性脊髄障害 / Molecular Mechanisms / Oncogenesis / Subtractive suppression hybridization / differentially expressed gene / subtractive cloning / development / cerebellum / differentially expressed genes / subtractive Cloning / hedgehog signal / wnt signal / 遊走能 / チミジンキナーゼ / ガンシクロビル / 多能性幹細胞 / 悪性グリオーマ / 遺伝子治療 / viral thymidine kinase / migration / stem cells / mesenchvmal stem cell / brain tumor / mesenchymal stem cell / neural stem cell / herpes simplex virus-thymidine kinase / 脳腫瘍学 Less

Exome analysis of glioma malignant transformation mutation and development of differentiation method by blood secretory vesicle analysis
- Principal Investigator
  
  Minoshima Shinsei
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Genetically-engineered multilineage-differentiating stress-enduring cells as cellular vehicles against malignant gliomas
- Principal Investigator
  
  Namba Hiroki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Malignant glioma tropism of induced pluripotent stem cellPrincipal Investigator
- Principal Investigator
  
  TOKUYAMA tsutomu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Use of mesenchymal stem cells as a vector for glioma gene therapy
- Principal Investigator
  
  NAMBA Hiroki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Role of developmental regulated genes in biological properties of medulloblastoma
- Principal Investigator
  
  YOKOTA Naoki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Spinal Reproduction with Neuronal Stem Cell Implantation for Ischernic Spinal Cord Injury
- Principal Investigator
  
  TERADA Hitoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Hamamatsu University School of Medicine
Analyses of Molecular Mechanisms underlying Medulloblastoma Oncogenesis
- Principal Investigator
  
  NAMBA Hiroki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine

All 2015 2011 2008 2007 2006

All Journal Article Presentation

[Journal Article] Potent tumor tropism of induced pluripotent stem cells and induced pluripotent stem cell-derived neural stem cells in the mouse intracerebral glioma model2015
- Author(s)
  Yamazoe T, Koizumi S, Yamasaki T, Amano S, Tokuyama T, Namba H
- Journal Title
  
  Int J Oncoｌ
  
  Volume: 46 Issue: 1 Pages: 147-152
- DOI
  10.3892/ijo.2014.2702
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293306
[Journal Article] Interferon-β and temozolomide combination therapy for temozolomide monotherapy-refractory malignant gliomas2015
- Author(s)
  Kawaji H, Tokuyama T, Yamasaki T, Amano S, Sakai N, Namba H
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 3 Pages: 909-913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293306
[Journal Article] Migration of mouse-induced pluripotent stem cells to glioma-conditioned medium is mediated by tumor-associated specific growth factors2011
- Author(s)
  Koizumi S, Gu C, Amano S, Yamamoto S, Ihara H, Tokuyama T, Namba H
- Journal Title
  
  Oncol Lett
  
  Volume: 2(2) Pages: 283-288
- Data Source
  KAKENHI-PROJECT-23592119
[Journal Article] Synovial chondromatosis of the temporomandibular joint with intracranial extension2008
- Author(s)
  Yokota N, Inenaga C, Tokuyama T, Nishizawa S, Miura K, Namba H
- Journal Title
  
  Neurol Med Chir 48
  
  Pages: 266-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390394
[Journal Article] Genetically engineered neural stem cells migrate and suppress glioma cell growth at distant intracranial sites2007
- Author(s)
  Li S, Gao Y, Tokuyama T, Yamamoto J, Yokota N, Yamamoto S, Terakawa S, Kitagawa M, Namba H
- Journal Title
  
  Cancer Lett 251
  
  Pages: 220-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390394
[Journal Article] Monitoring of singlet oxygen is useful for predicting the photodynamic effects in the treatment for experimental glioma2006
- Author(s)
  Yamamoto J, Yamamoto S, Hirano T, Li S, Koide M, Kohno E, Okada M, Inenaga C, Tokuyama T, Yokota N, Terakawa S, Namba H
- Journal Title
  
  Clin Cancer Res 12
  
  Pages: 7132-7139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390394
[Presentation] 単純ヘルペスウイルスチミジンキナーゼ導入iPS細胞を用いたグリオーマ治療2011
- Author(s)
  山添知宏、小泉慎一郎、徳山勤、酒井直人、山崎友裕、起本由美子、金子新、中内啓光、難波宏樹
- Organizer
  第12回日本分子脳神経外科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23592119
[Presentation] 自殺遺伝子導入人工多能性幹細胞のglioma治療への応用2011
- Author(s)
  小泉慎一郎、山添知宏、徳山勤、酒井直人、山﨑友裕、起本由美子、金子新、中内啓光、難波宏樹
- Organizer
  第70日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23592119
[Presentation] modulates migration and tropism of mesenchymal stem cells2008
- Author(s)
  難波宏樹、高芸、李少一、谷春雨、徳山勤、横田尚樹
- Organizer
  第14回日本遺伝子治療学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390394
[Presentation] Bystander effect between mesenchymal stem cells and brain tumor cells in the HSV-TK/GCV system is not species specific2007
- Author(s)
  難波宏樹、李少一、高芸、徳山勤、横田尚樹
- Organizer
  第13回日本遺伝子治療学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390394
[Presentation] 間葉系幹細胞をベクターとして用いる脳腫瘍の遺伝子治療2007
- Author(s)
  難波宏樹、徳山勤、横田尚樹、李少一
- Organizer
  第66回日本脳神経外科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390394
[Presentation] Use of genetically engineered mesenchymal stem cells for treatment of experimental gliomas2006
- Author(s)
  難波宏樹、李少一、徳山勤、山本淳考、横田尚樹
- Organizer
  第12回日本遺伝子治療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390394

1. NAMBA Hiroki (60198405)

# of Collaborated Projects: 6 results

# of Collaborated Products: 12 results
2. YOKOTA Naoki (00273186)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. NISHIKAWA Shigeru (40135257)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KOIDE Masayo (40324347)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAKAMURA Satoki (20377740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OHNISHI Kazunori (80252170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. DEZAWA MARI (50272323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OHTA Seiji (80283365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TERADA Hitoshi (80334978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAZUI Teruhisa (20094203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Minoshima Shinsei (90181966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 天野慎士 (70464138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. GAO Yun (60402343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 大坪正史 (10327653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 足立直樹 (70300853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TOKUYAMA tsutomu 徳山 勤

TOKUYAMA Tsutomu 徳山 勤

Research Projects

Research Products

Co-Researchers

Exome analysis of glioma malignant transformation mutation and development of differentiation method by blood secretory vesicle analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetically-engineered multilineage-differentiating stress-enduring cells as cellular vehicles against malignant gliomas

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Malignant glioma tropism of induced pluripotent stem cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Use of mesenchymal stem cells as a vector for glioma gene therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of developmental regulated genes in biological properties of medulloblastoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Spinal Reproduction with Neuronal Stem Cell Implantation for Ischernic Spinal Cord Injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of Molecular Mechanisms underlying Medulloblastoma Oncogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Potent tumor tropism of induced pluripotent stem cells and induced pluripotent stem cell-derived neural stem cells in the mouse intracerebral glioma model2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interferon-β and temozolomide combination therapy for temozolomide monotherapy-refractory malignant gliomas2015

Author(s)

Journal Title

Data Source

[Journal Article] Migration of mouse-induced pluripotent stem cells to glioma-conditioned medium is mediated by tumor-associated specific growth factors2011

Author(s)

Journal Title

Data Source

[Journal Article] Synovial chondromatosis of the temporomandibular joint with intracranial extension2008

Author(s)

Journal Title

Data Source

[Journal Article] Genetically engineered neural stem cells migrate and suppress glioma cell growth at distant intracranial sites2007

Author(s)

Journal Title

Data Source

[Journal Article] Monitoring of singlet oxygen is useful for predicting the photodynamic effects in the treatment for experimental glioma2006

Author(s)

Journal Title

Data Source

[Presentation] 単純ヘルペスウイルスチミジンキナーゼ導入iPS細胞を用いたグリオーマ治療2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 自殺遺伝子導入人工多能性幹細胞のglioma治療への応用2011

Author(s)

Organizer

TOKUYAMA tsutomu 徳山勤

TOKUYAMA Tsutomu 徳山勤