NAMBA Hiroki 難波宏樹

… Alternative Names

Researcher Number	60198405
Other IDs
Affiliation (Current)	2021: 浜松医科大学, 医学部, 特命研究教授
Affiliation (based on the past Project Information) *help	2010 – 2019: 浜松医科大学, 医学部, 教授 2017: 浜松医科大学, 医学部附属病院, 教授 1999 – 2008: 浜松医科大学, 医学部, 教授 2004: Hamamatsu University School of Medicine, Neurosurgery, Professor, 医学部, 教授
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Cerebral neurosurgery / Neurosurgery Except Principal Investigator Neurosurgery / Cerebral neurosurgery / Gastroenterology / Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related / Thoracic surgery / Surgical dentistry / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator gene therapy / ganciclovir / bystander effect / herpes simplex virus-thymidine kinase / brain tumor / glioma / medulloblastoma / 脳腫瘍学 / neural stem cell / mesenchymal stem cell … More Except Principal Investigator 自殺遺伝子療法 / PET / CYP2C9 / NSAID / 胃粘膜傷害 / 遺伝子多型 / 悪性グリオーマ / パーキンソン病 / ドパミン / ドパミン受容体 / 磁気 / 電気インピーダンス / 脳循環 / 脳虚血 / magnetic field / electrical impedance / DNA microarray / medulloblastoma / 視床下核 / 自殺遺伝子幹細胞療法 / 脳腫瘍学 / 脳腫瘍 / 遺伝子治療 / 個別化療法 / H2S / 低用量アスピリン / H. pylori / SLCO1B1 / Aspirin / UGT1A6 / アスピリン / 抗血小板薬 / クロピドグレル / 人工多能性幹細胞 / 移動能 / iPS細胞 / bystander効果 / mesenchymal stem cell / 呼気試験 / ナプロキセン / 13C / 呼気テスト / NSAIDS / Naproxen / 13CO2 / Prostaglandin / 脳深部刺激術 / 内側前縦束 / ラットパーキンソン病モデル / 視床下核刺激 / 淡蒼球刺激 / cerebral circulation / cerebral ischemia / ミトコンドリア / 神経細胞 / ^<11>C-Pyruvate / 興奮性神経細胞死 / ラット / サル / 一過性局所脳虚血 / Pyruvate / Rhodamine / mitochondria / ^<11>C-pyruvate / excitotoxicity / ischemia-reperfusion / rat / monkey / 虚血性脊髄障害 / 神経幹細胞移植 / 神経再生治療 / ラット対麻痺モデル / 脊髄虚血 / ischemic spinal cord injury / neuronal stem cell implantation / spinal reproduction / paraplegia model of rat / 局所脳循環 / 非侵襲 / cerebral blood flow / less invasive / tetra-polar circuit method / 髄芽腫 / 腫瘍形成機構 / 癌遺伝子 / 発生関連遺伝子 / 幹細胞 / 定量的RT-PCR / developmentally regulated / biological property / oncogenesis / differentiation / proliferation / cancer stem cell / siRNA / molecular mechanisms / oncogene / developmentally regulated gene / stem cell / semi-quantitative RT-PCT / パーキンソン氏病 / サルモデル / 脳深部電気刺激術 / 分子イメージング研究 / MPTPサルモデル / 脳深部電気刺激 / 分子イメージング / MPTP全身投与サルモデル / HSVｔｋ/GCV　ｓｙｓｔｅｍ / ＰｉｇｇｙＢａｃ　system / エピソーマルベクター / HSVtk/GCV system / 間葉系幹細胞 / 脂肪由来骨髄間葉系幹細胞 / 脳神経外科学 / HSVtk遺伝子 / 頭蓋内腫瘍 / 硬さ / 弾性率 / MRI / MRE / エラストグラフィー / 脳神経外科 / MR Elastography / intracranial tumors / stiffness / consisitency / meningioma / pituitary adenoma / vestibular schwannoma / glioma / shear stiffness / tumor consistency / meningiomas / pituitary adenomas / vestibular shwannoma / gliomas / 淡蒼球 / 視床下核脳深部刺激 / 淡蒼球脳深部刺激 / 細胞治療 / HSVtk / TERT / 製剤化 / 遺伝子導入 / 歯髄幹細胞 / bystander effect / Muse-tk細胞 / 抗腫瘍効果 / 転移性脳腫瘍 Less

悪性グリオーマ治療の製剤化に向けたHSVtk遺伝子導入細胞株の構築Ongoing
- Principal Investigator
  
  池野正史
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Aichi Medical University
単純ヘルペスチミジンキナーゼ遺伝子導入Muse細胞を用いた肺癌脳転移新規治療戦略Ongoing
- Principal Investigator
  
  鮫島哲朗
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hamamatsu University School of Medicine
Positron emmission tomography study of dopamine release by subthalamic nucleus and pallidal stimulation in Parkinson's diseae model rats.
- Principal Investigator
  
  杉山憲嗣
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hamamatsu University School of Medicine
自殺遺伝子幹細胞療法による口腔扁平上皮癌新規治療戦略
- Principal Investigator
  
  山崎佳寿美
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hamamatsu University School of Medicine
HSVtk遺伝子導入Muse細胞を用いた膠芽腫治療戦略と生体モニタリングの開発
- Principal Investigator
  
  山崎友裕
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Development of suicide gene stem cell therapy by non-viral gene transfer method and application to glioma therapy
- Principal Investigator
  
  sameshima tetsuro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Treatment study to brain tumor Using mesenchymal stem cell
- Principal Investigator
  
  Amano Shinji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Shear stiffness of intracranial tumors using MRE
- Principal Investigator
  
  Sakai Naoto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
[13C]-naproxen breath test can predict the gastric mucosal injury induced by naproxen
- Principal Investigator
  
  FURUTA TAKAHISA
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hamamatsu University School of Medicine
A study of dopamine release in Parkinson'disease-deep brain stimulation model rat by using PET scan
- Principal Investigator
  
  Sugiyama Kenji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Genetically-engineered multilineage-differentiating stress-enduring cells as cellular vehicles against malignant gliomasPrincipal Investigator
- Principal Investigator
  
  Namba Hiroki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Suicide gene theraphy for malignant glioma using induced pluripotent stem cells
- Principal Investigator
  
  Amano Shinji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Effects of parameters of the Deep brain stimulation on the therapeutic efficacy in MPTP treated monkey, a PET study
- Principal Investigator
  
  ASAKAWA Tetsuya
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Development of genomics-based prophylaxis strategy for gastric mucosal injury induced by anti-platelet agents
- Principal Investigator
  
  FURUTA TAKAHISA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hamamatsu University School of Medicine
Malignant glioma tropism of induced pluripotent stem cell
- Principal Investigator
  
  TOKUYAMA tsutomu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Development of genomics-based prophylaxis strategy for NSIAD ulcer
- Principal Investigator
  
  FURUTA Takahisa
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hamamatsu University School of Medicine
Use of mesenchymal stem cells as a vector for glioma gene therapyPrincipal Investigator
- Principal Investigator
  
  NAMBA Hiroki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Role of developmental regulated genes in biological properties of medulloblastoma
- Principal Investigator
  
  YOKOTA Naoki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Spinal Reproduction with Neuronal Stem Cell Implantation for Ischernic Spinal Cord Injury
- Principal Investigator
  
  TERADA Hitoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Hamamatsu University School of Medicine
Development of new-designed device ("simultaneous transcranial measurement system of multiple electrical pulse impedances using multi-polar circuit method") to measure local cerebral blood flow
- Principal Investigator
  
  NISHIZAWA Shigeru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
The study for imaging, in vivo, brain mitochondrial. dysfunction using positron emission tomography
- Principal Investigator
  
  YAMAMOTO Seiji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Analyses of Molecular Mechanisms underlying Medulloblastoma OncogenesisPrincipal Investigator
- Principal Investigator
  
  NAMBA Hiroki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Development of New System for Cerebral Blood Flow Measurement Using Tetrapolar Circuit Method
- Principal Investigator
  
  NISIZAWA Shigeru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
Bystander effect-mediated suicide gene therapy of experimental brain tumor by genetically engineered tumor cells in ratPrincipal Investigator
- Principal Investigator
  
  NAMBA Hiroki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine

All 2019 2018 2017 2016 2015 2013 2012 2011 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Can the Latest Computerized Technologies Revolutionize Conventional Assessment Tools and Therapies for a Neurological Disease? The Example of Parkinson’s Disease2019
- Author(s)
  Asakawa T*, Sugiyama K, Nozaki T, Sameshima T, Kobayashi S, Wang L, Hong Z, Chen S, Li C, Namba
- Journal Title
  
  Neurologia medico-chirurgica
  
  Volume: 59 Issue: 3 Pages: 69-78
- DOI
  10.2176/nmc.ra.2018-0045
- NAID
  130007612818
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08991, KAKENHI-PROJECT-15K10358, KAKENHI-PROJECT-18K08966
[Journal Article] Fluid-Blood Level and Hematoma Expansion in a Cerebral Amyloid Angiopathy-Associated Intracerebral Hematoma2019
- Author(s)
  Suzuki Ryoichi、Yamasaki Tomohiro、Koizumi Shinichiro、Nozaki Takao、Hiramatsu Hisaya、Sameshima Tetsuro、Sugiyama Kenji、Namba Hiroki
- Journal Title
  
  American Journal of Case Reports
  
  Volume: 20 Pages: 844-850
- DOI
  10.12659/ajcr.915919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08966
[Journal Article] Deep Brain Stimulation for Intractable Obsessive-compulsive Disorder: The International and Japanese Situation/Scenario2018
- Author(s)
  Sugiyama K, Nozaki T, Asakawa T, Sameshima T, Koizumi S, Hiramatsu H, Namba H.
- Journal Title
  
  Neurologia medico-chirurgica
  
  Volume: 58 Issue: 9 Pages: 369-376
- DOI
  10.2176/nmc.st.2018-0115
- NAID
  130007484382
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08966, KAKENHI-PROJECT-18K08991, KAKENHI-PROJECT-15K10358
[Journal Article] Effect of Subthalamic Deep Brain Stimulation on Upper Limb Dexterity in Patients with Parkinson Disease2018
- Author(s)
  Nozaki T, Asakawa T, Sugiyama K, Koda Y, Shimoda A, Mizushima T, Sameshima T, Namba H.
- Journal Title
  
  World Neurosurg
  
  Volume: 115
- DOI
  10.1016/j.wneu.2018.04.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08966, KAKENHI-PROJECT-18K08991, KAKENHI-PROJECT-15K10358
[Journal Article] Current behavioral assessments of movement disorders in children2018
- Author(s)
  Asakawa T, Sugiyama K, Nozaki T, Sameshima T, Kobayashi S, Wang L, Hong Z, Chen SJ, Li CD, Ding D, Namba H.
- Journal Title
  
  CNS Neurosci Ther
  
  Volume: 24 Pages: 863-875
- DOI
  10.1111/cns.13036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08966, KAKENHI-PROJECT-18K08991, KAKENHI-PROJECT-15K10358
[Journal Article] The efficacy of resection of an intradural extramedullary foramen magnum cavernous malformation presenting with repeated subarachnoid hemorrhage2017
- Author(s)
  Oishi T, Sakai N, Sameshima T, Kawaji H, Namba H
- Journal Title
  
  J Med Case Reports
  
  Volume: 11 Pages: 63-63
- DOI
  10.1186/s13256-017-1220-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293306
[Journal Article] Shear Stiffness of 4 Common Intracranial Tumors Measured Using MR Elastography: Comparison with Intraoperative Consistency Grading2017
- Author(s)
  Sakai N, Takehara Y, Yamashita S, Oishi N, Kawaji H, Sameshima T, Baba S, Sakahara H, Namba H
- Journal Title
  
  AJNR Am J Neuroradiol
  
  Volume: 36 Pages: 1851-1859
- DOI
  10.3174/ajnr.a4832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293306
[Journal Article] Human behavioral assessments in current research of Parkinson's disease2016
- Author(s)
  Asakawa T*, Fang H, Sugiyama K, Nozaki T, Hong Z, Yang Y, Hua F, Ding G, Chao D, Fenoy AJ, Villarreal SJ, Onoe H, Suzuki K, Mori N, Namba H, Xia Y*.
- Journal Title
  
  Neurosci Biobehav Rev
  
  Volume: 65 Pages: 741-72
- DOI
  10.1016/j.neubiorev.2016.03.016
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10358, KAKENHI-PROJECT-26293264, KAKENHI-PROJECT-26462201
[Journal Article] Animal behavioral assessments in current research of Parkinson's disease2016
- Author(s)
  Asakawa T, Fang H, Sugiyama K, Nozaki T, Kobayashi S, Hong Z, Suzuki K, Mori N, Yang Y, Hua F, Ding G, Wen G, Namba H, Xia Y.
- Journal Title
  
  Neuroscience & Biobehavioral Reviews
  
  Volume: Jun 29 Pages: 1-20
- DOI
  10.1016/j.neubiorev.2016.06.036
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293264, KAKENHI-PROJECT-15K10358, KAKENHI-PROJECT-26462201
[Journal Article] Shear Stiffness of 4 Common Intracranial Tumors Measured Using MR Elastography: Comparison with Intraoperative Consistency Grading2016
- Author(s)
  N.Sakai, Y.Takehara, S. Yamashita、N. Ohishi, H. Kawaji, T. Sameshima, S. Baba, H. Sakahara, H. Namba
- Journal Title
  
  AJNR Am J Neuroradiol
  
  Volume: 37 Pages: 1851-1859
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10359
[Journal Article] Use of genetically engineered stem cells for glioma therapy2016
- Author(s)
  Namba H, Kawaji H, Yamasaki T
- Journal Title
  
  Oncol Lett
  
  Volume: 11 Pages: 9-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293306
[Journal Article] Potent tumor tropism of induced pluripotent stem cells and induced pluripotent stem cell-derived neural stem cells in the mouse intracerebral glioma model2015
- Author(s)
  Yamazoe T, Koizumi S, Yamasaki T, Amano S, Tokuyama T, Namba H
- Journal Title
  
  Int J Oncoｌ
  
  Volume: 46 Pages: 147-152
- DOI
  10.3892/ijo.2014.2702
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293306
[Journal Article] The Present Indication and Future of Deep Brain Stimulation2015
- Author(s)
  Sugiyama K*, Nozaki T, Asakawa T, Koizumi S, Saito O , Namba H
- Journal Title
  
  Neurologia medico-chirurgica
  
  Volume: 55 Issue: 5 Pages: 416-421
- DOI
  10.2176/nmc.ra.2014-0394
- NAID
  130005069874
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10358, KAKENHI-PROJECT-26462201, KAKENHI-PROJECT-24592157
[Journal Article] Interferon-β and temozolomide combination therapy for temozolomide monotherapy-refractory malignant gliomas2015
- Author(s)
  Kawaji H, Tokuyama T, Yamasaki T, Amano S, Sakai N, Namba H
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 3 Pages: 909-913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293306
[Journal Article] Neuroprotective Effect of Neuroserpin in Oxy-gen-Glucose Deprivation-and Reoxygenation-Treated Rat Astrocytes In Vitro2015
- Author(s)
  Wang L, Zhang Y, Asakawa T*, Li W, Han S, Li Q, Xiao B, Namba H, Lu C, Dong Q
- Journal Title
  
  PLOS ONE
  
  Volume: 10
- DOI
  10.1371/journal.pone.0123932
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10358, KAKENHI-PROJECT-24592157
[Journal Article] Behavioral Performance at Early (4 Weeks) and Later (6 Months) Stages in Rats With Unilateral Medial Forebrain Bundle and Striatal 6-Hydroxydopamine Lesions2013
- Author(s)
  14． Wei SUN, Kenji SUGIYAMA, Tetsuya ASAKAWA, Tae ITO-YAMASHITA, Hiroki NAMBA
- Journal Title
  
  Neurologia medico-chirurgica
  
  Volume: 53 Issue: 1 Pages: 7-11
- DOI
  10.2176/nmc.53.7
- NAID
  10031138763
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592157
[Journal Article] Chaihu-Shugan-San Administration Ameliorates Perimenopausal Anxiety and Depression in Rats2013
- Author(s)
  Shujiao Chen,Tetsuya Asakawa, Shanshan Ding, Linghong Liao, Lingyuan Zhang, Jianying Shen, Jie Yu, Kenji Sugiyama, Hiroki Namba, Candong Li
- Journal Title
  
  PLOS ONE.
  
  Volume: 8
- DOI
  10.1371/journal.pone.0072428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592157
[Journal Article] The food reaching test : a sensitive test of behavioral improvements by deep brain stimulation in MPTP-treated monkey2012
- Author(s)
  Tetsuya Asakawa
- Journal Title
  
  Neurosci Res
  
  Volume: 74 Pages: 122-128
- DOI
  10.1016/j.neures.2012.07.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500379, KAKENHI-PROJECT-24592157, KAKENHI-PROJECT-24790269
[Journal Article] Peripheral stimulation in treating Parkinson's disease: Is it a realistic idea or a romantic whimsicality?2012
- Author(s)
  Asakawa T, Fang H, Hong Z, Sugiyama K, Nozaki T, Namba H
- Journal Title
  
  Intractable Rare Dis Res.
  
  Volume: 1 Pages: 144-150
- NAID
  130003397547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592157
[Journal Article] Effects of Ghrelin on the Intracellular Calcium Concentration in Rat Aorta Vascular Smooth Muscle Cells.2012
- Author(s)
  Fang H, Hong Z, Zhang J, Shen DF, Gao FF, Sugiyama K, Namba H, Asakawa T
- Journal Title
  
  Cell Physiol Biochem.
  
  Volume: 30 Pages: 1299-1309
- DOI
  10.1159/000343319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592157
[Journal Article] Effect of subthalamic nucleus stimulation during exercise on the mesolimbocortical dopaminergic region inParkinson's disease:a positron emission tomography study2012
- Author(s)
  Nozaki T, Sugiyama K, Yagi S, Yoshikawa E, Kanno T, Asakawa T, Ito T, Terada T, Namba H, Ouchi Y
- Journal Title
  
  J Cereb Blood Flow Metab.
  
  Volume: 33 Pages: 415-421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592157
[Journal Article] Migration of mouse-induced pluripotent stem cells to glioma-conditioned medium is mediated by tumor-associated specific growth factors2011
- Author(s)
  Koizumi S, Gu C, Amano S, Yamamoto S, Ihara H, Tokuyama T, Namba H
- Journal Title
  
  Oncol Lett
  
  Volume: 2(2) Pages: 283-288
- Data Source
  KAKENHI-PROJECT-23592119
[Journal Article] 腹壁内血腫の1例-大腿動脈穿刺によるセルジンガー法のピットフォール2009
- Author(s)
  平松久弥、杉浦康仁、竹田理々子、難波宏樹
- Journal Title
  
  脳神経外科 37
  
  Pages: 167-171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390394
[Journal Article] Multifaceted effects of selective inhibitor of phosphodiesterase III, cilostazol, for cerebral vasospasm aftersubarachnoid hemorrhage in dog model2009
- Author(s)
  Okada M, Namba H
- Journal Title
  
  Cerebrovasc Dis (in press)
- Data Source
  KAKENHI-PROJECT-18390394
[Journal Article] Asymptomatic non-functioning ectopic pituitary adenoma in the suprasellar region : a case report2009
- Author(s)
  Mizutani A, Okada M, Yokota N, Namba H
- Journal Title
  
  Brit J Neurosurg (in press)
- Data Source
  KAKENHI-PROJECT-18390394
[Journal Article] 脳動脈瘤の3D cine PCMRI流体解析とこれを境界条件とした計算流体力学解析の比較2009
- Author(s)
  礒田治夫、大倉靖栄、小杉隆司、山下修平、竹原康雄、竹田浩康、平野勝也、難波宏樹、Marcus T. Alley、oland Banner、Nobert J. Pelc、阪原晴海
- Journal Title
  
  日磁医誌 29
  
  Pages: 33-35
- NAID
  10026287405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390394
[Journal Article] MRによる脳動脈瘤血流解析2008
- Author(s)
  礒田治夫、平野勝也、竹田浩康、大倉靖栄、小杉隆司、山下修平、竹原康雄、難波宏樹、Marcus T. Alley、阪原晴海
- Journal Title
  
  臨床放射線 53
  
  Pages: 797-808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390394
[Journal Article] Synovial chondromatosis of the temporomandibular joint with intracranial extension2008
- Author(s)
  Yokota N, Inenaga C, Tokuyama T, Nishizawa S, Miura K, Namba H
- Journal Title
  
  Neurol Med Chir 48
  
  Pages: 266-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390394
[Journal Article] Genetically engineered neural stem cells migrate and suppress glioma cell growth at distant intracranial sites2007
- Author(s)
  Li S, Gao Y, Tokuyama T, Yamamoto J, Yokota N, Yamamoto S, Terakawa S, Kitagawa M, Namba H
- Journal Title
  
  Cancer Lett 251
  
  Pages: 220-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390394
[Journal Article] Monitoring of singlet oxygen is useful for predicting the photodynamic effects in the treatment for experimental glioma2006
- Author(s)
  Yamamoto J, Yamamoto S, Hirano T, Li S, Koide M, Kohno E, Okada M, Inenaga C, Tokuyama T, Yokota N, Terakawa S, Namba H
- Journal Title
  
  Clin Cancer Res 12
  
  Pages: 7132-7139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390394
[Presentation] STN-DBS術後のParkinson病患者における線条体腹側部のドパミントランスポーター増加：ミクログリア活性との関連について2019
- Author(s)
  野崎孝雄、杉山憲嗣、浅川哲也、門脇　慎、難波宏樹、横倉正倫、寺田達弘、尾内泰臣
- Organizer
  第58回日本定位・機能神経外科学会　２０１８／１／２５－２６、東京都
- Data Source
  KAKENHI-PROJECT-18K08966
[Presentation] Deep Brain Stimulation for Parkinson Disease -Comparison of STN- vs GPi-DBS in our institute.2019
- Author(s)
  Sugiyama K, Nozaki T, Asakawa T, Namba H
- Organizer
  Biannunal meeting of World Society for Stereotactic and Functional Neurosurgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08966
[Presentation] パーキンソン病に対する脳深部刺激術－当施設でのSTN-DBS とGPi-DBSの比較－2019
- Author(s)
  杉山憲嗣、野崎孝雄、浅川哲也、門脇　慎、難波宏樹
- Organizer
  第58回日本定位・機能神経外科学会　２０１８／１／２５－２６、東京都
- Data Source
  KAKENHI-PROJECT-18K08966
[Presentation] STN-DBS10年後のDBS効果とドパミン反応性の解離2019
- Author(s)
  杉山憲嗣、野崎孝雄、浅川哲也、門脇慎、難波宏樹
- Organizer
  日本脳神経外科学会第78回学術総会
- Data Source
  KAKENHI-PROJECT-18K08966
[Presentation] Deep Brain Stimulation for Bening Tremurous Parkinsonism2018
- Author(s)
  Kenji Sugiyama, Takao Nozaki, Tetsuya Asakawa, Hiroki Namba
- Organizer
  AASSFN 2018, Taiwan Sun-Moon Lake
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08966
[Presentation] Benign tremurous parkinsonismに対する脳深部刺激術2018
- Author(s)
  杉山憲嗣、野崎孝雄、浅川哲也、門脇　慎、難波宏樹
- Organizer
  第57回日本定位・機能神経外科学会　２０１８／１／１９－２０、奈良市
- Data Source
  KAKENHI-PROJECT-18K08966
[Presentation] 視床下核脳深部刺激術後のParkinson病患者における線条体腹側部のドパミントランスポーター増加：運動症状との関連について2018
- Author(s)
  野崎孝雄、杉山憲嗣、浅川哲也、難波宏樹、横倉正倫、寺田達弘、尾内泰臣
- Organizer
  第57回日本定位・機能神経外科学会　２０１８／１／１９－２０、奈良市
- Data Source
  KAKENHI-PROJECT-18K08966
[Presentation] Dissociation between effect of STN-DBS and dopaminergic responsiveness 10 years after STN-DBS surgery2017
- Author(s)
  Kenji Sugiyama, Takao Nozaki, Tetsuya Asakawa, Hiroshi Kawaji, Tomo Suzuki, Tomoya Ohishi, Hiroki Namba
- Organizer
  17th Quadrennial Meeting of world society for stereotactic and functional neurosurgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462201
[Presentation] 遺伝子導入ミューズ細胞を刺客として用いるグリオーマの遺伝子細胞治療2016
- Author(s)
  難波宏樹、山﨑友裕、小泉慎一郎、釼持博昭、若尾昌平、出澤真理
- Organizer
  第34回日本脳腫瘍学会
- Place of Presentation
  甲府
- Year and Date
  2016-12-04
- Data Source
  KAKENHI-PROJECT-25293306
[Presentation] 悪性グリオーマに対する刺客細胞としての遺伝子導入Muse細胞の応用2016
- Author(s)
  崎友裕、釼持博昭、難波宏樹
- Organizer
  第75回日本癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-25293306
[Presentation] Geneticlly-engineered multilineage-differentiated stess-enduring (MUSE) cells as a cellular assassins against malignant gliomas2016
- Author(s)
  Namba H, Yamasaki T, Wakao S, Dezawa M
- Organizer
  第22回日本遺伝子細胞治療学会学術集会
- Place of Presentation
  東京
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-25293306
[Presentation] HSV遺伝子導入Muse細胞の腫瘍指向性を用いた新規悪性グリオーマ治療戦略2016
- Author(s)
  山崎友裕、難波宏樹
- Organizer
  第75回日本脳神経外科学会総会
- Place of Presentation
  博多
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-25293306
[Presentation] 脳腫瘍治療の最新知見と核医学の役割2015
- Author(s)
  難波宏樹
- Organizer
  第61回関東核医学画像処理研究会
- Place of Presentation
  東京
- Year and Date
  2015-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-25293306
[Presentation] グリオーマの最新治療2015
- Author(s)
  難波宏樹
- Organizer
  横浜サイバーナイフセンター設立10周年記念講演会
- Place of Presentation
  横浜
- Year and Date
  2015-09-04
- Invited
- Data Source
  KAKENHI-PROJECT-25293306
[Presentation] Different Performance between Food Reaching Motors andFinger Precise Motors Ameliorated by STN-DBS in MPTP-treated Monkeys2013
- Author(s)
  Tetsuya Asakawa, Kenji Sugiyama, Takao Nozaki, Hiroki Namba.
- Organizer
  the 16th quadrennial meeting of the World Society of Stereotactic and Functional Neurosurgery (WSSFN)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24592157
[Presentation] Muse細胞をベクターとするグリオーマのHSVtk遺伝子細胞療法2013
- Author(s)
  難波宏樹
- Organizer
  第31回日本脳腫瘍学会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-25293306
[Presentation] Potent in vitro bystander effect and migratory activity in the suicide gene therapy using Muse cells transduced with herpes simplex virus thymidine kinase gene and ganciclovir2013
- Author(s)
  難波宏樹
- Organizer
  第19回日本遺伝子治療学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-25293306
[Presentation] The strategy of “stimulation” in treating Parkinson’s disease.2013
- Author(s)
  Tetsuya Asakawa, Kenji Sugiyama, Takao Nozaki, Hiroki Namba.
- Organizer
  China Neurology Forum (CNF) 2013
- Place of Presentation
  Shanghai China
- Invited
- Data Source
  KAKENHI-PROJECT-24592157
[Presentation] The brain areas activated by effective deep brain stimulation of subthalamic nucleus in MPTP treated monkeys, a H215O-PET study2012
- Author(s)
  浅川哲也，杉山憲嗣、山下たえ、野崎孝雄、尾上浩隆、塚田秀夫、難波宏樹
- Organizer
  第13回日本分子庁外科学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24592157
[Presentation] A potent in vitro bystander effect in the suicide gene therapy using iPS cells transduced with herpes simplex virus thymidine kinase gene and ganciclovir2011
- Author(s)
  難波宏樹、小泉慎一郎、山添知宏、起本由美子、金子新、中内啓光
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-23592119
[Presentation] 自殺遺伝子導入人工多能性幹細胞のglioma治療への応用2011
- Author(s)
  小泉慎一郎、山添知宏、徳山勤、酒井直人、山﨑友裕、起本由美子、金子新、中内啓光、難波宏樹
- Organizer
  第70日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23592119
[Presentation] 単純ヘルペスウイルスチミジンキナーゼ導入iPS細胞を用いたグリオーマ治療2011
- Author(s)
  山添知宏、小泉慎一郎、徳山勤、酒井直人、山崎友裕、起本由美子、金子新、中内啓光、難波宏樹
- Organizer
  第12回日本分子脳神経外科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23592119
[Presentation] p27 modulates migration and tropism of mesenchymal stem cells2008
- Author(s)
  難波宏樹
- Organizer
  第14回日本遺伝子治療学会
- Place of Presentation
  札幌
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-18390394
[Presentation] modulates migration and tropism of mesenchymal stem cells2008
- Author(s)
  難波宏樹、高芸、李少一、谷春雨、徳山勤、横田尚樹
- Organizer
  第14回日本遺伝子治療学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390394
[Presentation] 間葉系幹細胞をベクターとして用いる脳腫瘍の遺伝子治療2007
- Author(s)
  難波宏樹、徳山勤、横田尚樹、李少一
- Organizer
  第66回日本脳神経外科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390394
[Presentation] Bystander effect between mesenchymal stem cells and brain tumor cells in the HSV-TK/GCV system is not species specific2007
- Author(s)
  難波宏樹、李少一、高芸、徳山勤、横田尚樹
- Organizer
  第13回日本遺伝子治療学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390394
[Presentation] Neural stem cell therapy for malignant glioma2007
- Author(s)
  Hiroki Namba
- Organizer
  Congress of Neurological Surgeons Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-18390394
[Presentation] Use of genetically engineered mesenchymal stem cells for treatment of experimental gliomas2006
- Author(s)
  難波宏樹、李少一、徳山勤、山本淳考、横田尚樹
- Organizer
  第12回日本遺伝子治療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390394
[Presentation] パーキンソン氏病サルモデルにおけるSTN-DBS後の脳血流変化のPET研究
- Author(s)
  浅川哲也，杉山憲嗣、山下たえ、野崎孝雄、尾上浩隆、塚田秀夫、難波宏樹
- Organizer
  第34回関東機能的脳外科カンファレンス
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24592157
[Presentation] Stem Cell-based Gene Therapy for Malignant Brain Tumors
- Author(s)
  Hiroki Namba
- Organizer
  International Symposium toward the Future of Advanced Researches in Shizuoka University
- Place of Presentation
  Ｈａｍａｍａｔｓｕ
- Year and Date
  2015-01-27 – 2015-01-28
- Invited
- Data Source
  KAKENHI-PROJECT-25293306
[Presentation] HSVtk遺伝子導入Muse細胞を用いたグリオーマの遺伝子細胞療法
- Author(s)
  難波宏樹
- Organizer
  第32回日本脳腫瘍学会
- Place of Presentation
  舞浜
- Year and Date
  2014-11-30 – 2014-12-02
- Data Source
  KAKENHI-PROJECT-25293306
[Presentation] Potent in vivo bystander effect of the suicide gene therapy to glioblastoma using Muse cells transduced with herpes simplex virus thymidine kinase gene and ganciclovir
- Author(s)
  難波宏樹
- Organizer
  第20回日本遺伝子治療学会
- Place of Presentation
  東京
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25293306

1. TOKUYAMA Tsutomu (90313957)

# of Collaborated Projects: 6 results

# of Collaborated Products: 12 results
2. NISHIZAWA Shigeru (40135257)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. YOKOTA Naoki (00273186)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
4. MAGATA Yasuhiro (20209399)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. FURUTA Takahisa (10303546)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. OGAWA Noriyoshi (80308618)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. Amano Shinji (70464138)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
8. Sugiyama Kenji (00235904)

# of Collaborated Projects: 3 results

# of Collaborated Products: 26 results
9. ASAKAWA Tetsuya (00469917)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. 山崎友裕 (40781050)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. 小泉慎一郎 (10456577)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. WATANABE Hiroshi (50262803)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. SUGIMOTO Mitsushige (80397398)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. MATSUYAMA Yukihiro (20312316)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. TAKEMAE Tadashi (20115356)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. KOIDE Masayo (40324347)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. sameshima tetsuro (00295213)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. 野崎孝雄 (10598494)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
19. NAKAMURA Satoki (20377740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. OHNISHI Kazunori (80252170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. IKUMA Mutsuhiro (00275108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NISHINO Masafumi (10436975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YAMADE Mihoko (10464124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TAKEUCHI Kazuhiko (00419425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. UMEMURA Kazuo (40232912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. DEZAWA MARI (50272323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. TAGAWA Masatoshi (20171572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. YOKOYAMA Tetsuo (20166896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. YAMAMOTO Seiji (60144094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. OHTA Seiji (80283365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. TERADA Hitoshi (80334978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. KAZUI Teruhisa (20094203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. ONOE Hirotaka (80214196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
34. OUCHI Yashuomi (40436978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
35. Sakai Naoto (20550172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
36. 小平知世 (40436960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 大澤恵 (10397391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 杉本健 (20529507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. GAO Yun (60402343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 山崎佳寿美 (90794983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 加藤文度 (60204492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 竹原康雄 (70188217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
43. 山下修平 (90402312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 馬場聡 (10242760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
45. 池野正史 (80298546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 武内恒成 (90206946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. TSUKADA Hideo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. FANG Xin

# of Collaborated Projects: 0 results

# of Collaborated Products: 26 results
49. SHUKURI Miho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 鈴木勝昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
51. 杉山登志郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
52. 出沢真理

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

NAMBA Hiroki 難波 宏樹

NANBA Hiroki 難波 宏樹

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悪性グリオーマ治療の製剤化に向けたHSVtk遺伝子導入細胞株の構築Ongoing

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単純ヘルペスチミジンキナーゼ遺伝子導入Muse細胞を用いた肺癌脳転移新規治療戦略Ongoing

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Genetically-engineered multilineage-differentiating stress-enduring cells as cellular vehicles against malignant gliomasPrincipal Investigator

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NAMBA Hiroki 難波宏樹

NANBA Hiroki 難波宏樹