TAGAWA MASATOSHI 田川雅敏

… Alternative Names

Researcher Number	20171572
Other IDs
Affiliation (Current)	2020: 千葉大学, 大学院医学研究院, 特任教授 2020: 千葉県がんセンター(研究所), がん治療開発グループ, 特任研究員
Affiliation (based on the past Project Information) *help	2009 – 2018: Chiba Cancer Center (Research Institute), がん治療開発グループ, 部長 2015: 千葉県がんセンター研究所, 細胞治療開発研究部, 部長 2013: 千葉県がんセンター, 病理研究部, 部長 2011: 千葉県がんセンター, がん治療開発グループ, 部長 2010: 千葉県がんセンター(研究所), がん研究開発グループ, 部長 … More
Review Section/Research Field	Principal Investigator Digestive surgery / Digestive surgery / Biological Sciences Except Principal Investigator Orthopaedic surgery / Gastroenterology / Respiratory organ internal medicine / Biological Sciences / Cerebral neurosurgery / Immunology / Urology … More
Keywords	Principal Investigator 遺伝子治療 / ミッドカイン / VEGF / アデノウイルス / 食道がん / プロモーター / 自殺遺伝子 / 遺伝子 / Gene therapy / サイトカイン … More Except Principal Investigator 遺伝子治療 / gene therapy / アデノウイルス / アポトーシス / 遺伝子 / CD46 / サイトカイン / brain tumor / HSV-TK / 腫瘍プロモーター / 脊柱靱帯骨化症 / 培養脊柱靱帯細胞 / BMP-2 / 免疫学 / リンパ球 / シグナル伝達 / 転写調節 / 膵がん / 抗がん剤 / 細胞死 / CAR / 悪性中皮腫 / IL-2 / IL-12 / 自殺遺伝子 / glioma / ミッドカイン / c-erbB-2 / Midkine / Tumor promoter / DNA結合蛋白 / 脊柱靭帯骨化症 / 後縦靭帯骨化症 / 成因 / IGF-I / TGFβ1 / bFGF / 損傷乗り越えDNA合成 / 突然変異 / がん治療 / 膀胱癌 / ペメトレキセド / アデノウイルスベクター / p53経路 / Rb蛋白 / interleukin-2 / immunity / Brain Neoplasm / サイトカイン遺伝子 / IL-15 / IL-18 / Gene therapy / Transcriptional regulation / bystander effect / ganciclovir / herpes simplex virus-thymidine kinase / 自殺遺伝子治療 / HSV-tk / 樹状細胞 / TNF-α / 免疫遺伝子治療 / 増殖 / 遺伝子発現 / 転写因子 / CD40 / lymphocyte / proliferation / transcription factor / サバイビン / Survivin / グリオーマ / Gene Therapy / 腫瘍融解性ウイルス / E1A / small G-proteins / vaccine / immune therapy / NF-1 / E1 / メラノ-マ抗原 / GM3結合蛋白 / 内在性抗原 / Zn-finger構造 / 人工抗原 / 細胞培養 / 骨芽細胞 / twyマウス / コラーゲン / アルカリフォスファターゼ / 副甲状腺ホルモン(PTH) / 培養脊柱靭帯細胞 / TGF-β / BMP / ALP活性 / TGF-β1 / オステロネクチン / ファイブロネクチン / DNAポリメラーゼζ / 発がん / ノックアウトマウス / 細胞がん化 / DNA修復 / 膵臓がん / ウイルス / 細胞傷害活性 / E1A遺伝子 / MDM-7 / ファイバー・ノブ領域 / インターロイキン24 / MDA-7 / EIA遺伝子 / AdMKE1a / 導入効率 / バルプロ酸Na / AdMKEla / 膵臓癌 / 遺伝子医薬 / オートファジー / cytopathic effect / p53 / アデノイルス / G2/M期 / 細胞周期 / 塩酸ゲムシタビン / Geldanamycin / 肺癌 / Th17 細胞 / 血管新生 / 血管新生因子 / Th17 / 腎臓癌 / CD46蛋白質 / 抗腫瘍効果 / ビスフォスフォネート / siRNA / E1B / メラノーマ抗原 / GM3 / GM3-ラクトン / ゲノムDNAクローニング / ガン抗原 / メラノーマ / メラノーマ関連遺伝子 / シナプス小胞 / シナプトファイシン / 82K蛋白 / モノクロ-ナル抗体 / シナプス後部濃物質 / 免疫組織化学 / 免疫電顕 / 82k蛋白 / シナプトフィシン / 神経細胞 / シナプス複合体 / synaptic vesicle / synaptophysin / 82K protein / monoclonal antibody / postsynaptic density / immunohistochemistry / immunoelectron microscopy / Gene Thetapy / Antitumor Immumty / Major Histocoispastibility Complex / Herpes Sumpley Virus-Thymidine Kinase / 大腸がん / 飲酒 / 葉酸代謝酵素(MTHFR) / Colorectal cancer / Folic acid / MTHFR / Alcohol / 転写制御 / レトロウイルス / Cyotokine / Suicide gene / 乳癌 / c-erbB2 / 腫瘍特異的プロモーター / c-erB2 / RREAST CANCER / SUICIDE GENE THERAPY / TUMOR SPECIFIC PROMOTER / midkine / アデノウィルスベクター / Th1タイプサイトカイン / Colon26 / Colon 26 / Th1サイトカイン / DENDRITIC CELLS / ADENORICUS VECTOR / TH1 TYPE CYTOKINES / COLON 26 / CD40リガンド / Fasリガンド / 肺がん / 肺転移 / 抗原提示 / 樹上細胞 / CD40 ligand / Fas ligand / lung cancer / lung metastasis / antigen presentaion / dendritic cells / 神経芽腫 / NEUROBLASTOMA / IMMUNOGENE THERAPY / SUCIDE GENE THERAPY / 免疫応答 / B細胞抗原レセプター / gene expression / immune response / B cell antigen receptor / レポーターアッセイ / c-erb-B-2 / Reporter assay / 神経前駆細胞 / インターロイキン-2 / Antitamor Immunity / Neural Progenitor Cell / IL-4 / GM-CSF / Glioma / Cytokine / immune gene therapy / neural progenitor cell / Interleukin-2 / in vivo電気穿孔法 / 消化器癌 / p53遺伝子 / 消火器癌 / in vivo electroporation / gastrointestinal cancer / p53 gene / suicide gene / cytokine / 分化 / differentiation / apoptosis / 転写調節領域 / SCIDマウス / Transcription regulatory region / Oncolytic virus / SCID mouse / peptide / CD45 / ウイルス増殖 / シャトルベクター / E3ファイバー領域 / 細胞受容体 / Adenovirus / Pancreatic cancer / カテプシンD / 腫瘍浸潤 / プロテアーゼ / プロテオミクス / 腫瘍マーカー / cathepsin D / invasion / proteases / proteomics / 抑制T細胞 / Vα14α鎖遺伝子 / 多様性欠除 / 自己反応性レパトア / 胸腺非依存性の選択 / 分子生物学 / 免疫系ネットワ-ク / 抑制T細胞リセプター / α鎖遺伝子 / トランスジェニック・マウス / 免疫応答調節 / 抑制T細胞レセプター / V_α遺伝子ゲノム塩基配列 / Antiーsense RNA / 抗原レセプター / 内部抗原 / キメラ・マウス / Suppresser T cell receptor / T cell repertoire / Homogenous TCR usage / Valpha14 TCR gene family / TCRalpha-chain / Self reactive repertoire / Bリンパ球分化・成熟 / 造血幹細胞 / 遺伝子再構成 / 幼若B細胞特異遺伝子 / μ鎖複合体 / 細胞内シグナル伝達 / allelic exclusion / μ鎖結合蛋白分子 / 幼若造血細胞クロ-ン / 分化拘束 / 胎生期胸腺内B前駆細胞 / 胸腺由来未分化造血細胞株 / V遺伝子発現におけるプログラム / μ鎖複合体とシグナル伝達 / B cell differentiation / Signal transduction / mu chain complexes / B cell specific genes / hematopoietic cell clones / hematopoietic cell differentiation / fatal thymus / Abelson murine leukemia virus / 薬物耐性 / CARP / AMPK / ANKRD1 / 耐性 / 薬剤耐性 / 増殖因子 / インシュリン様増殖因子 / 化学療法 / Hippo経路 / 細胞障害活性 / MDM2阻害剤 / MDM2 / FAK / 低分子G蛋白 / AMPK-mTOR / MDM4 / NF2 / Mdm2 / Mdm4 / ユビキチン化 / トランスレーショナルリサーチ / バイオテクノロジー Less

Molecular therapy for esophageal cancer targeting the p53 and the Hippo pathwaysPrincipal InvestigatorOngoing
- Principal Investigator
  
  田川雅敏
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba Cancer Center (Research Institute)
A therapeutic strategy for malignant mesothelioma with reconstituting tumor suppressor pathways which were defective due to the characteristic genetic deletion
- Principal Investigator
  
  Shingyoji Masato
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba Cancer Center (Research Institute)
A novel cancer therapeutics with gene medicine and molecular targeted agents directing the p53 pathways in esophageal carcinomaPrincipal Investigator
- Principal Investigator
  
  Tagawa Masatoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba Cancer Center (Research Institute)
Development of targeted therapy to overcome drug resistance in malignant mesothelioma
- Principal Investigator
  
  SEKINE Ikuo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  University of Tsukuba
  Chiba Cancer Center (Research Institute)
Activation of the p53 pathway by gene medicine and a chemotherapeutic agent produces anti-tumor effects on human mesothelioma cells
- Principal Investigator
  
  MASATO Shingyoji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba Cancer Center (Research Institute)
Combinatory use of replication-competent adenoviruses and chemotherapeutic agents produces anti-tumor effects on human esophageal carcinoma cellsPrincipal Investigator
- Principal Investigator
  
  TAGAWA Masatoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba Cancer Center (Research Institute)
Development of new therapy using novel chimeric oncolytic adenoviruse vector for intractable bladder cancer.
- Principal Investigator
  
  GOTOH Akinobu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Hyogo College of Medicine
INVOLVMENT OF TH17 CELLS IN TUMOR ANGIOGENESIS INDUCED BY INTERACION BETWEEN NON-SMALL CELL LUNG CANCER CELLS AND INTERSTITIAL STROMAL CELLS
- Principal Investigator
  
  NUMASAKI Muneo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Josai University
Anti-tumor effects for solid tumors in digestive tracts were produced by a chimeric type of oncolytic adenoviruses and the carrier cells
- Principal Investigator
  
  KAWAMURA Kiyoko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Chiba Cancer Center (Research Institute)
Mesenchymal stem cells infected with modified adenoviruses as carrier cells that target human gastrointestinal tumorsPrincipal Investigator
- Principal Investigator
  
  TAGAWA Masatoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba Cancer Center (Research Institute)
Conditionally Replicative Adenovirus for Targeting Bladder Cancer.
- Principal Investigator
  
  TERAO Shuji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Hyogo College of Medicine
Therapeutic strategies with chimeric oncolytic adenoviruses and a cell-mediated delivery system for gastrointestinal solid tumors
- Principal Investigator
  
  KAWAMURA Kiyoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Chiba Cancer Center (Research Institute)
改変型細胞融解性ウイルスを搭載する間葉系幹細胞を用いた難治性消化器癌の治療Principal Investigator
- Principal Investigator
  
  田川雅敏
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba Cancer Center (Research Institute)
Multifunctional therapeutic strategy for malignant gliomas targeting cathepsin D
- Principal Investigator
  
  IWADATE Yasuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Chiba University
Gene therapy for gastrointestinal tumors with adenovirus in which the fiber-knob region was replaced
- Principal Investigator
  
  KAWAMURA Kiyoko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Chiba Cancer Center Research Institute
Oncolytic adenovirus modified to increase its infectivity for gastrointestinal cancerPrincipal Investigator
- Principal Investigator
  
  TAGAWA Masatoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba Cancer Research Institute
Development of glioma-specific peptide vaccine targeting small G-proteins
- Principal Investigator
  
  IWADATE Yasuo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Chiba University
Role of novel genes expressed in activated B cells in the regulation of immune responses
- Principal Investigator
  
  O-WANG Jiyang
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  RIKEN
Gene therapy for intractable gastrointestinal tumors with tumor promoter-mediated oncolyitc adenoviruses
- Principal Investigator
  
  KAWAMURA Kiyoko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Chiba Cancer Center Research Institute
不忠実なDNAポリメラーゼ群の突然変異誘発及び発がん過程で果たす役割の解明
- Principal Investigator
  
  王継揚
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba Cancer Center (Research Institute)
Development of multimodal gene therapy for gastrointestinal cancer using in vivo electroporation
- Principal Investigator
  
  MATSUBARA Hisairo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
B細胞の抗体産生とアポトーシスを制御する新規遺伝子in vivoにおける機能
- Principal Investigator
  
  王継揚
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba Cancer Center (Research Institute)
Functional analysis of novel genes involved in the regulation of B cell activation and death
- Principal Investigator
  
  OH Keiyou
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Chiba Cancer Center Research Institute
Suicide gene therapy for intractable gastrointestinal cancer with tumor specific promoters
- Principal Investigator
  
  KAWAMURA Kiyoko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Chiba Cancer Center Research Institute
Gene therapy for gastrointestinal tumors using antigen presenting cells activated with gene transferPrincipal Investigator
- Principal Investigator
  
  TAGAWA Masatoshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba Cancer Center Research Institute
Cytokine gene therapy for brain tumors using neural progenitor cells
- Principal Investigator
  
  IWADATE Yasuo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Chiba University
DNA複製エラーを惹起するDNAポリメラーゼ・ゼータが発がん過程で果たす役割
- Principal Investigator
  
  OH Keiyou
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba Cancer Center (Research Institute)
遺伝子導入によって活性化された樹状細胞による抗原提示能の強化に基づいた抗腫瘍効果Principal Investigator
- Principal Investigator
  
  田川雅敏
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba Cancer Center (Research Institute)
SUICIDEAND IMMUNE GENE THERAPY USING TUMOR SPECIFIC PROMOTOR FOR BREAST CANCER
- Principal Investigator
  
  MATSUBARA Hisahiro, 宮内基博
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  CHIBA UNIVERSITY
  Chiba Cancer Center (Research Institute)
THERAPEUTIC EFFECT OF DENDRITIC CELLS TRANSDUCED WITH TH1-TYPE-CYTOKINE-GENES BY RECOMBINANT ADENOVIRUS VECTOR ON GASTROINTESTINAL TUMOR GROWTH
- Principal Investigator
  
  GUNJI Yoshio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  CHIBA UNIVERSITY
Forced expression of the TNF-family gene in lung cancer cells produced therapeutic effects, stimulating antigen-presentation processes.
- Principal Investigator
  
  KOSHIKAWA Nobuko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Chiba Cancer Center Research Institute
GENE THERAPY FOR NEUROBLASTOMA
- Principal Investigator
  
  YOSHIDA Hideo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  CHIBA UNIVERSITY
腫瘍で高発現を示す遺伝子のプロモーター領域を応用した自殺遺伝子治療Principal Investigator
- Principal Investigator
  
  田川雅敏
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Chiba Cancer Center (Research Institute)
Therapeutic effects of cytokine gene therapy and suicide gene therapy for gastrointestinal tumors
- Principal Investigator
  
  KAWAMURA Kiyoko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Chiba Cancer Center Research Institute
Suicide gene therapy for gastrointestinal tumors using tumor-specific promotersPrincipal Investigator
- Principal Investigator
  
  TAGAWA Masatoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba Cancer Center Research Institute
Bystander effect-mediated suicide gene therapy of experimental brain tumor by genetically engineered tumor cells in rat
- Principal Investigator
  
  NAMBA Hiroki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hamamatsu University School of Medicine
腫瘍において高発現をみる遺伝子のプロモーターを用いた自殺遺伝子治療の基礎的検討Principal Investigator
- Principal Investigator
  
  田川雅敏
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Chiba Cancer Center (Research Institute)
アルコール代謝ならびに葉酸代謝酵素の遺伝的多型と大腸がんに関する疫学的研究
- Principal Investigator
  
  MURATA Motoi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Chiba Cancer Center Research Institute
Immune gene therapy for gastrointestinal cancer by activation Th1-type helper T cells.Principal Investigator
- Principal Investigator
  
  TAGAWA Masatoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba Cancer Center Research Institute
Basic Research for The Immuno-genetherapy of Brain Tumors
- Principal Investigator
  
  IWADATE Yasuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  CHIBA UNIVERSITY
SCIDマウスを用いたサイトカイン遺伝子治療のin vivoモデルの確立Principal Investigator
- Principal Investigator
  
  田川雅敏
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
脊柱靱帯骨化症の発生に関与する骨増殖因子の解明と臨床応用のための基礎的研究
- Principal Investigator
  
  後藤澄雄
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Chiba University
ヒト腫瘍細胞・TILを用いたサイトカイン遺伝子治療のin vivoモデルの確立Principal Investigator
- Principal Investigator
  
  田川雅敏
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
脊柱靱帯骨化症の発生に関与する骨増殖因子の解明と臨床応用のための基礎的研究
- Principal Investigator
  
  後藤澄雄
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Chiba University
脊柱靱帯骨化症の発生に関与する骨増殖因子の解明と臨床応用のための基礎的研究
- Principal Investigator
  
  後藤澄雄
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Chiba University
脊柱靭帯骨化症の発生に関与する骨増殖促進因子の解明と臨床応用のための基礎的研究
- Principal Investigator
  
  後藤澄雄
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Chiba University
脊柱靭帯骨化症の発症に関与せる骨増殖促進因子の解明と臨床応用のための基礎的研究
- Principal Investigator
  
  後藤澄雄
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Chiba University
Expression and localization of the synapse specific proteins in central nervous system of the postnatal rat.
- Principal Investigator
  
  KADOTA Tomoko
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  神経解剖学
- Research Institution
  Chiba University, School of Medicine
腫瘍抗原の分子免疫学的研究
- Principal Investigator
  
  谷口克
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
Analysis of lymphoid cell differentiation
- Principal Investigator
  
  TAKEMORI Toshitada
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  National Institute of Health
  Chiba University
腫瘍抗原の分子免疫学的研究
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
腫瘍抗原の分子免疫学的研究
- Principal Investigator
  
  谷口克
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
Molecualr mechanisms of cell-cell interactions and T cell repertoire formation.
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1986 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  Chiba University

[Book] Midkine: From embryogenesis to pathogenesis and therapy.2012
- Author(s)
  Tagawa, M., Kawamura, K., Yu, L., Tada, Y., Hiroshima, K. and Shimada, H.
- Total Pages
  319
- Publisher
  Springer-Verlag Gmbh
- Data Source
  KAKENHI-PROJECT-23591951
[Book] Mesotheliomas-synonyms and definition, epidemiology, etiology, pathogenesis, cyto-histopathological features, clinic, diagnosis, treatment, prognosis.2012
- Author(s)
  Fukamachi, T., Saito, H., Tagawa, M. and Kobayashi, H.
- Total Pages
  244
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23591951
[Book] Cellular and genetic practices for translational medicine.2011
- Author(s)
  Tagawa, M., その他
- Total Pages
  260
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-23591951
[Book] Type III interferon family-mediated anti-tumor responses through multiple mechanisms. In : Cellular and genetic practices for translational medicine. ed. by Jong-Young Kwak and Jin-Yeong Han2011
- Author(s)
  Tagawa, M., Tada, Y., Hiroshima, K. and Shimada, H.
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-23591951
[Book] Cancer Gene Therapy2010
- Author(s)
  Masatoshi Tagawa
- Total Pages
  249
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-20591585
[Book] Cancer Gene Therapy2010
- Author(s)
  Tagawa, M.
- Total Pages
  249
- Publisher
  Research Signpost, Kerala, India.
- Data Source
  KAKENHI-PROJECT-20591585
[Journal Article] A p53-stabilizing agent, CP-31398, induces p21 expression with increased G2/M phase through the YY1 transcription factor in esophageal carcinoma defective of the p53 pathway.2019
- Author(s)
  Zhong, B., Shingyoji, M., Hanazono, M., Nguyen, T.T.T., Morinaga, T., Tada, Y., Hiroshima, K., Shimada, H. and Tagawa, M.
- Journal Title
  
  Am. J. Cancer Res.
  
  Volume: ９ Pages: 79-93
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10617
[Journal Article] Heat shock protein 90 inhibitors augment endogenous wild-type p53 expression but down-regulate the adenovirally-induced expression by inhibiting a proteasome activity2018
- Author(s)
  Chai Kuan、Ning Xuerao、Nguyen Thao Thi Thanh、Zhong Boya、Morinaga Takao、Li Zhihan、Shingyoji Masato、Tada Yuji、Tatsumi Koichiro、Shimada Hideaki、Hiroshima Kenzo、Yamaguchi Naoto、Tagawa Masatoshi
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 26130-26143
- DOI
  10.18632/oncotarget.25452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10520, KAKENHI-PROJECT-16K09598
[Journal Article] Augmented expression of cardiac ankyrin repeat protein is induced by pemetrexed and a possible marker for the pemetrexed resistance in mesothelioma cells2017
- Author(s)
  Qin Yiyang、Sekine Ikuo、Fan Mengmeng、Takiguchi Yuichi、Tada Yuji、Shingyoji Masato、Hanazono Michiko、Yamaguchi Naoto、Tagawa Masatoshi
- Journal Title
  
  Cancer Cell Int
  
  Volume: 17 Pages: 1-11
- DOI
  10.1186/s12935-017-0493-8
- NAID
  120006401860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09598, KAKENHI-PROJECT-17K09647, KAKENHI-PROJECT-15K07922, KAKENHI-PROJECT-26461183
[Journal Article] Cytotoxicity of replication-competent adenoviruses powered by an exogenous regulatory region is not linearly correlated with the viral infectivity/gene expression or with the E1A-activating ability but is associated with the p53 genotypes2017
- Author(s)
  Yamauchi Suguru、Zhong Boya、Kawamura Kiyoko、Yang Shan、Kubo Shuji、Shingyoji Masato、Sekine Ikuo、Tada Yuji、Tatsumi Koichiro、Shimada Hideaki、Hiroshima Kenzo、Tagawa Masatoshi
- Journal Title
  
  BMC Cancer
  
  Volume: 17 Pages: 622-622
- DOI
  10.1186/s12885-017-3621-x
- NAID
  120006347288
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10617
[Journal Article] Metformin produces growth inhibitory effects in combination with nutlin-3a on malignant mesothelioma through a cross-talk between mTOR and p53 pathways2017
- Author(s)
  Shimazu Kengo、Tada Yuji、Morinaga Takao、Shingyoji Masato、Sekine Ikuo、Shimada Hideaki、Hiroshima Kenzo、Namiki Takao、Tatsumi Koichiro、Tagawa Masatoshi
- Journal Title
  
  BMC Cancer
  
  Volume: 17 Pages: 309-309
- DOI
  10.1186/s12885-017-3300-y
- NAID
  120006224641
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09598
[Journal Article] Panel of autoantibodies against multiple tumor-associated antigens for detecting gastric cancer.2017
- Author(s)
  Hoshino, I., Nagata, M., Takiguchi, N., Nabeya, Y., Ikeda, A., Yokoi, S., Kuwajima, A., Tagawa, M., Matsushita, K., Yajima, S., Shimada, H.
- Journal Title
  
  Cancer Science
  
  Volume: 108 Pages: 308-315
- DOI
  10.1111/cas.13158
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462000, KAKENHI-PROJECT-26462002, KAKENHI-PROJECT-15K10117, KAKENHI-PROJECT-16K10520, KAKENHI-PROJECT-26460951
[Journal Article] An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced.2017
- Author(s)
  Morinaga Takao、Nguyen Thao Thi Thanh、Zhong Boya、Hanazono Michiko、Shingyoji Masato、Sekine Ikuo、Tada Yuji、Tatsumi Koichiro、Shimada Hideaki、Hiroshima Kenzo、Tagawa Masatoshi
- Journal Title
  
  Virology Journal
  
  Volume: 14 Pages: 219-219
- DOI
  10.1186/s12985-017-0888-0
- NAID
  120006368231
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10617, KAKENHI-PROJECT-16K21639
[Journal Article] Clinical significance of serum autoantibodies against Ras-ｌike GTPases, RalA, in patients with esophageal squamous cell carcinoma.2016
- Author(s)
  Nanami, T., Shimada, H., Yajima, S., Oshima, Y., Matsushita, K., Nomura, F., Nagata, M., Tagawa, M., Otsuka, S., Kuwajima, A. and Kaneko, H
- Journal Title
  
  Esophagus
  
  Volume: 13 Pages: 167-172
- DOI
  10.1007/s10388-015-0510-8
- NAID
  40020807867
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462000, KAKENHI-PROJECT-16K10519, KAKENHI-PROJECT-16K10520
[Journal Article] An intrapleural administration of zoledronic acid for inoperable malignant mesothelioma patients: a phase I clinical study protocol.2016
- Author(s)
  Tada, Y., Hiroshima, K., Shimada, H., Shingyoji, M., Suzuki, T., Umezawa, H., Sekine, I., Takiguchi, Y., Tatsumi, K. and Tagawa, M.: An intrapleural administration of zoledronic acid for inoperable malignant mesothelioma patients: a phase I clinical study protocol
- Journal Title
  
  SpringerPlus
  
  Volume: 5 Pages: 195-202
- DOI
  10.1186/s40064-016-1893-2
- NAID
  120005753018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461183
[Journal Article] Combination of a third generation bisphosphonate and replication-competent adenoviruses augments the cytotoxicity on mesothelioma2016
- Author(s)
  Jiang, Y., Zhong, B., Kawamura, K., Morinaga, T., Shingyoji, M., Sekine, I., Tada, Y., Tatsumi, K., Shimada, H., Hiroshima, K. and Tagawa, M.
- Journal Title
  
  BMC Cancer
  
  Volume: 16 Pages: 455-455
- DOI
  10.1186/s12885-016-2483-y
- NAID
  120005829742
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462000, KAKENHI-PROJECT-16K09598, KAKENHI-PROJECT-26461183
[Journal Article] NY-ESO-1 autoantibody as a tumor-specific biomarker for esophageal cancer: screening in 1969 patients with various cancers.2016
- Author(s)
  Oshima Y, Shimada H, Yajima S, Nanami T, Matsushita K, Nomura F, Kainuma O, Takiguchi N, Soda H, Ueda T, Iizasa T, Yamamoto N, Yamamoto H, Nagata M, Yokoi S, Tagawa M, Ohtsuka S, Kuwajima A, Murakami A, Kaneko H
- Journal Title
  
  J. Gastroenterol.
  
  Volume: Epub ahead of print Pages: 30-34
- DOI
  10.1007/s00535-015-1078-8
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591961, KAKENHI-PROJECT-26462029, KAKENHI-PROJECT-26460951, KAKENHI-PROJECT-26462000
[Journal Article] Cytotoxic effects of replication-competent adenoviruses on human esophageal carcinoma are enhanced by forced p53 expression.2015
- Author(s)
  Yang, S., Kawamura, K., Okamoto, S., Yamauchi, S., Shingyoji, M., Sekine, I., Kobayashi, H., Tada, Y., Tatsumi, K., Hiroshima, K., Shimada, H. and Tagawa, M.
- Journal Title
  
  BMC Cancer
  
  Volume: 15 Pages: 464-464
- DOI
  10.1186/s12885-015-1482-8
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462000
[Journal Article] Fas ligand DNA enhances a vaccination effect by coadministered DNA encoding a tumor antigen through augmenting production of antibody against the tumor antigen.2015
- Author(s)
  Zhong, B., Ma, G., Sato, A., Shimozato, O., Liu, H., Li, Q., Shingyoji, M., Tada, Y., Tatsumi, K., Shimada, H., Hiroshima, K. and Tagawa, M.
- Journal Title
  
  J Immunol Res
  
  Volume: 2015 Pages: 743828-743828
- DOI
  10.1155/2015/743828
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591185
[Journal Article] Molecular-targeted therapy for malignant mesothelioma2015
- Author(s)
  Tada, Y., Suzuki, T., Shimada, H., Hiroshima, K., Tatsumi, K. and Tagawa, M
- Journal Title
  
  Pleura
  
  Volume: 1 Pages: 1-11
- DOI
  10.1177/2373997515600403
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461183
[Journal Article] A clinical protocol to inhibit the HGF/c-Met pathway for malignant mesothelioma with an intrapleural injection of adenoviruses expressing the NK4 gene.2015
- Author(s)
  Tada, Y., Hiroshima, K., Shimada, H., Morishita, N., Shirakawa, T., Matsumoto, K., Shingyoji, M., Sekine, I., Tatsumi, K. and Tagawa, M.
- Journal Title
  
  SpringerPlus
  
  Volume: 4 Pages: 358-358
- DOI
  10.1186/s40064-015-1123-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461183, KAKENHI-PROJECT-15K14473
[Journal Article] Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions2014
- Author(s)
  Okamoto, S., Jiang, Y., Kawamura, K., Shingyoji, M., Tada, Y., Sekine, I., Takiguchi, Y., Tatsumi, K., Kobayashi, H., Shimada, H., Hiroshima, K. and Tagawa, M.
- Journal Title
  
  Cell Death ＆ Disease
  
  Volume: ５
- DOI
  10.1038/cddis.2014.475
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591185, KAKENHI-PROJECT-26860622
[Journal Article] Mesenchymal stem cells are efficiently transduced with adenoviruses bearing type 35-derived fibers and the transduced cells with the IL-28A gene produces cytotoxicity to lung carcinoma cells co-cultured.2014
- Author(s)
  Suzuki, T., Kawamura, K., Li, Q, Okamoto, S., Tada, Y., Tatsumi, K., Shimada, H., Hiroshima, K., Yamaguchi, N. and Tagawa, M.
- Journal Title
  
  BMC Cancer
  
  Volume: 14 Pages: 713-713
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462000
[Journal Article] Combination of adenoviruses expressing melanoma differentiation-associated gene-7 and chemotherapeutic agents produces enhanced cytotoxicity on esophageal carcinoma.2014
- Author(s)
  Ma, G., Kawamura, K., Yang, S., Okamoto, S., Li, Q., Namba, M., Shingyoji, M., Tada, Y., Tatsumi, K., Hiroshima, K., Shimada, H. and Tagawa, M.
- Journal Title
  
  Cancer Gene Ther.
  
  Volume: 21 Pages: 31-37
- DOI
  10.1038/cgt.2013.79
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-26462000
[Journal Article] Gene therapy for malignant mesothelioma : Current prospects and challenges2013
- Author(s)
  Tagawa, M., Tada, Y., Shimada, H. and Hiroshima, K.
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 20 Pages: 150-156
- DOI
  10.1038/cgt.2013.1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591951
[Journal Article] Fiber-substituted conditionally replicating adenovirus Ad5F35 induces oncolysis of human bladder cancer cells in in vitro analysis.2013
- Author(s)
  Gotoh A, Nagaya H, Kanno T, Tagawa M, Nishizaki T.
- Journal Title
  
  Urology
  
  Volume: 81
- DOI
  10.1016/j.urology.2012.12.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-23592354
[Journal Article] Heat-shock protein 90 inhibitors synergistically enhance melanoma differentiation-associated gene-7-mediated cell killing of human pancreatic carcinoma.2013
- Author(s)
  Zhang, M., Kawamura, K., Jiang, Y., Shingyoji, M., Ma, G., Li, Q., Hu, J., Qi, Y., Liu, H., Zhang, F., Kang, S., Shan, B., Wang, S., Chada, S. and Tagawa, M.
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 20 Pages: 663-670
- DOI
  10.1038/cgt.2013.6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591185
[Journal Article] Enhanced antitumor efficacy of fiber-modified, midkine promoter-regulated oncolytic adenovirus in human malignant mesothelioma.2013
- Author(s)
  Takagi-Kimura, M., Yamano, T., Tamamoto, A., Okamura, N., Okamura, H., Hashimoto-Tamaoki, T., Tagawa, M., Kasahara, N. and Kubo, S.
- Journal Title
  
  Cancer Science
  
  Volume: 104 Pages: 1433-1439
- DOI
  10.1111/cas.12267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-25460484
[Journal Article] CD90 is a diagnostic marker to differentiate between malignant pleural mesothelioma and lung carcinoma with immunohistochemistry.2013
- Author(s)
  Kawamura, K., Hiroshima, K., Suzuki, T., Chai, K., Yamaguchi, N., Shingyoji, M., Yusa, T., Tada, Y., Takiguchi, Y., Tatsumi, K., Shimada, H. and Tagawa, M.
- Journal Title
  
  Am. J. Clin. Pathol.
  
  Volume: 140 Pages: 544-549
- DOI
  10.1309/ajcpm2z4ngiipbge
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-24591185
[Journal Article] Fiber-substituted conditionally replicating adenovirus Ad5F35 induces oncolysis of human bladder cancer cells in in vitro analysis2013
- Author(s)
  Gotoh A, Nagaya H, Kanno T, Tagawa M, Nishizaki T
- Journal Title
  
  Urology
  
  Volume: 81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592354
[Journal Article] Interferon-beta produces synergistic combinatory anti-tumor effects with cisplatin or pemetrexed on mesothelioma cells.2013
- Author(s)
  Li Q, Kawamura K, Yang S, Okamoto S, Kobayashi H, Tada Y, Sekine I, Takiguchi Y, Shingyouji M, Tatsumi K, Shimada H, Hiroshima K, Tagawa M
- Journal Title
  
  PLoS ONE
  
  Volume: 8(8)
- DOI
  10.1371/journal.pone.0072709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-24591185
[Journal Article] Zoledronic acid produces combinatory anti-tumor effects with cisplatin on mesothelioma by increasing p53 expression levels.2013
- Author(s)
  Okamoto, S., Jiang, Y., Kawamura, K., Shingyoji, M., Fukamachi, T., Tada, Y., Takiguchi, Y., Tatsumi, K., Shimada, H., Hiroshima, K., Kobayashi, H. and Tagawa, M.
- Journal Title
  
  PLoS one
  
  Volume: 8
- DOI
  10.1371/journal.pone.0060297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591185, KAKENHI-PROJECT-24591961
[Journal Article] Fiber-substituted conditionally replicating adenovirus for oncolysis of human renal carcinoma cells2012
- Author(s)
  Nagaya, H., Tagawa, M., Hiwasa, K., Terao, S., Kanno, T., Nishizaki, T. and Gotoh, A.
- Journal Title
  
  Anticancer Res.
  
  Volume: 32 Pages: 2985-2990
- URL
  http://ar.iiarjournals.org/content/32/7/2985.abstract
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591951
[Journal Article] Antitumor effect of chondroitin sulfate-coated ternary GMCSF plasmid complex for ovarian cancer2012
- Author(s)
  Katsuyuki Hamada, 他
- Journal Title
  
  The Journal of Gene Medicine
  
  Volume: 14 Pages: 120-127
- DOI
  10.1002/jgm.1647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500430, KAKENHI-PROJECT-23240133, KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-23592453, KAKENHI-PROJECT-23700564
[Journal Article] E1B-55kD-defective adenoviruses activate p53 in mesothelioma and enhance cytotoxicity of anti-cancer agents.2012
- Author(s)
  Yamanaka, M, Tada, Y, Kawamura, K, Li, Q, Okamoto, S, Chai, K, Yokoi, S, Liang, M, Fukamachi, T, Kobayashi, H, Yamaguchi, N, Kitamura, A, Shimada, H, Hiroshima, K, Takiguchi, Y, et al.
- Journal Title
  
  J. Thorac. Oncol.
  
  Volume: 7 Pages: 1850-1857
- DOI
  10.1097/jto.0b013e3182725fa4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-24591185
[Journal Article] Fiber-substituted conditionally replicating adenovirus for oncolysis of human renal carcinoma cells.2012
- Author(s)
  Nagaya H, Tagawa M, Hiwasa K, Terao S, Kanno T, Nishizaki T Gotoh A.
- Journal Title
  
  Anticancer Res
  
  Volume: 32 Pages: 2985-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592354
[Journal Article] Impact of serum biomarkers on esophageal squamous cell carcinoma.2012
- Author(s)
  Shimada H, Yajima S, Oshima Y, Hiwasa T, Tagawa M, Matsushita K, Nomura F
- Journal Title
  
  Esophagus
  
  Volume: 9(3) Pages: 131-140
- DOI
  10.1007/s10388-012-0332-x
- NAID
  40019427695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591416, KAKENHI-PROJECT-23591948, KAKENHI-PROJECT-23591951
[Journal Article] Interaction and cross-resistance of cisplatin and pemetrexedin malignant pleural mesothelioma cell lines.2012
- Author(s)
  Kitazono-Saitoh M, Takiguchi Y, Sakaida E, Sekine I, Tanabe N, et al
- Journal Title
  
  Oncol. Rep.
  
  Volume: 28(1) Pages: 33-40
- DOI
  10.3892/or.2012.1799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590850, KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-24591185
[Journal Article] Zoledronic Acid Produces Antitumor Effects on Mesothelioma Through Apoptosis and S-Phase Arrest in p53-Independent and Ras prenylation-Independent Manners.2012
- Author(s)
  Okamoto, S., Kawamura, K., Li, Q., Yamanaka, M., Yang, S., Fukamachi, T., Tada, Y., Tatsumi, T., Shimada, H., Hiroshima, K., Kobayashi, H. and Tagawa, M.
- Journal Title
  
  Journal of thoracic oncology
  
  Volume: 7 Pages: 873-882
- DOI
  10.1097/jto.0b013e31824c7d43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591185, KAKENHI-PROJECT-24591961
[Journal Article] Upregulated p53 expression activates apoptotic pathways in wild-type p53-bearing mesothelioma and enhances cytotoxicity of cisplatin and pemetrexed.2012
- Author(s)
  Li, Q., Kawamura, K., Okamoto, S., Yamanaka, M., Yang, S., Yamauchi, S., Fukamachi, T., Kobayashi, H., Tada, Y., Takiguchi, Y., Tatsumi, K., Shimada, H., Hiroshima, K. and Tagawa, M.
- Journal Title
  
  Cancer Gene Ther.
  
  Volume: 19 Pages: 218-228
- DOI
  10.1038/cgt.2011.86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590879, KAKENHI-PROJECT-22590850, KAKENHI-PROJECT-22591416, KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-24591185
[Journal Article] Fiber-substituted conditionally replicating adenovirus for oncolysis of human renal carcinoma cells.2012
- Author(s)
  Nagaya, H., Tagawa, M., Hiwasa, K., Terao, S., Kanno, T., Nishizaki, T. and Gotoh, A.
- Journal Title
  
  Anticancer Res.
  
  Volume: 32 Pages: 2985-2990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591951
[Journal Article] Expression of a murine homolog of apoptosis-inducing human IL-24/MDA-7 in murine tumors fails to induce apoptosis or produce anti-tumor effects.2012
- Author(s)
  Nagakawa H, Shimozato O, 他9名
- Journal Title
  
  Cell Immunol.
  
  Volume: 275 Pages: 90-97
- DOI
  10.1016/j.cellimm.2012.02.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790397, KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-23591978, KAKENHI-PROJECT-24590496
[Journal Article] A possible anti-cancer agent, type III interferon, activates cell death pathways and produces anti-tumor effects (Article ID 479013)2011
- Author(s)
  Tagawa, M., Kawamura, K., Li, Q., Tada, Y., Hiroshima, K. and Shimada, H.
- Journal Title
  
  Clin. Dev. Immunol.
  
  Volume: 2011 Pages: 1-6
- DOI
  10.1155/2011/479013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590879, KAKENHI-PROJECT-23591951
[Journal Article] Antitumor activity of type III interferon alone or in combination with type I interferon against human non-small-cell lung cancer2011
- Author(s)
  Fujie, H., Tanaka, T., Tagawa, M., Kaijun, N., Watanabe, M., Suzuki, T., Nakayama, K. and Numasaki, M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 1977-1990
- NAID
  120005518441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591951
[Journal Article] Adenoviruses-mediated transduction of human oesophageal carcinoma cells with the interferon-1 genes produced anti-tumour effects2011
- Author(s)
  Li Q, Kawamura K, Okamoto S, Fujie H, Numasaki M, Namba M, Nagata M, Shimada H, Kobayashi H, Tagawa M
- Journal Title
  
  British Journal of Cancer
  
  Volume: 105 Pages: 1302-1312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590869
[Journal Article] Type III interferon alone or in combination with type I interferon inhibits the growth of human non-small cell lung cancer in vitro and in vivo.2011
- Author(s)
  Hitomi Fujie, Toshiaki Tanaka, Saori Ishiyama, Masatoshi Tagawa, Katsutoshi Nakayama, Takashi Suzuki, Muneo Numasaki.
- Journal Title
  
  Cancer Science
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590869
[Journal Article] A Distinct Regulatory Role of the Th17 Cytokines IL-17A and IL-17F in Chemokine Secretion from Lung Microvascular Endothelial Cells.2011
- Author(s)
  Hitomi Fujie, Saori Ishiyama, Masatoshi Tagawa, Niu Kaijun, Haruki Kitazawa, Yoshihisa Tomioka, Muneo Numasaki.
- Journal Title
  
  Inflammation
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590869
[Journal Article] Adenoviruses-mediated transduction of human esophageal carcinoma cells with the interferon-genes produced anti-tumor effects2011
- Author(s)
  Li, Q., Kawamura, K., Okamoto, S., Fujie, H., Numasaki, M., Namba, M., Nagata, M., Shimada, H., Kobayashi, H. and Tagawa, M.
- Journal Title
  
  Br. J. Cancer.
  
  Volume: 105 Pages: 1302-1132
- DOI
  10.1038/bjc.2011.379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590879, KAKENHI-PROJECT-22590869, KAKENHI-PROJECT-23591951
[Journal Article] Antitumor activity of type III interferon alone or in combination with type I interferon against human non-small cell lung cancer2011
- Author(s)
  Fujie H, Tanaka T, Tagawa M, Kaijun N, Watanabe M, Suzuki T, Nakayama K, Numasaki M
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 1977-1990
- NAID
  120005518441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590869
[Journal Article] Antitumor activity of type III interferon alone or in combination with type I interferon against human non-small-cell lung cancer.2011
- Author(s)
  Fujie H、 Tanaka T、Tagawa M、 Kaijun N、 Watanabe M、 Suzuki T、 Nakayama K、 Numasaki M
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 1977-1990
- DOI
  10.1111/j.1349-7006.2011.02079.x
- NAID
  120005518441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590869, KAKENHI-PROJECT-23591951
[Journal Article] Tumor specific low pH environment enhance the cytotoxicity of lovastatin and cantharidin2010
- Author(s)
  Fukamachi, T., Chiba, Y., Wang, X., Saito, H., Tagawa, M. and Kobayashi, H.
- Journal Title
  
  Cancer Lett
  
  Volume: 297 Pages: 182-189
- DOI
  10.1016/j.canlet.2010.05.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590879
[Journal Article] Interferon-lambda induces G1 phase arrest or apoptosis in oesophageal carcinoma cells and produces anti-tumour effects in combination with anti-cancer agents2010
- Author(s)
  Li Q、 Kawamura K、 Ma G、 Iwata F、 Numasaki M、 Suzuki N、 Shimada H、Tagawa M
- Journal Title
  
  Eur. J. Cancer
  
  Volume: 46 Pages: 180-190
- DOI
  10.1016/j.ejca.2009.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590869
[Journal Article] Interferon-λ induces G1 phase arrest or apoptosis in esophageal carcinoma cells and produces anti-tumor effects in combination with anti-cancer agents.2010
- Author(s)
  Li Q., Kawamura K., Ma G., Iwata F., Numasaki M., Suzuki N., Shimada H., Tagawa M.
- Journal Title
  
  Eur.J.Cancer 46
  
  Pages: 180-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591585
[Journal Article] Combinatory cytotoxic effects produced by E1B-55kDa-deleted adenoviruses and chemotherapeutic agents are dependent on the agents in esophageal carcinoma2010
- Author(s)
  Ma, G., Kawamura, K., Li, Q., Okamoto, S., Suzuki, N., Kobayashi, H., Liang, M., Tada, Y., Tatsumi, K., Hiroshima, K., Shimada, H. and Tagawa, M.
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 17 Pages: 803-813
- DOI
  10.1038/cgt.2010.37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590879
[Journal Article] Combinatory cytotoxic effects produced by E1B-55kDa-deleted adenoviruses and chemotherapeutic agents are dependent on the agents in esophageal carcinoma.2010
- Author(s)
  Ma G., Kawamura K., Li Q., Okamoto S., Suzuki N., Kobayashi H., Liang M., Tada Y., Tatsumi K., Hiroshima K., Shimada H., Tagawa M.
- Journal Title
  
  Cancer Gene Ther. 17
  
  Pages: 803-813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591585
[Journal Article] Cytotoxicity of adenoviruses expressing the wild-type p53 gene to esophageal carcinoma cells is linked with the CAR expression level and indirectly with the endogenous p53 status2009
- Author(s)
  Ma, G., Kawamura, K., Li, Q., Suzuki, N., Liang, M., Namba, M., Shimada, H. and Tagawa, M.
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 16 Pages: 832-840
- DOI
  10.1038/cgt.2009.21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590879
[Journal Article] Cytotoxicity of adenoviruses expressing the wild-type p53 gene to esophageal carcinoma cells is linked with the CAR expression level and indirectly with the endogenous p53 status.2009
- Author(s)
  Ma G., Kawamura K., Li Q., Suzuki N., Liang M., Namba M., Shimada H., Tagawa M.
- Journal Title
  
  Cancer Gene Ther. 16
  
  Pages: 832-840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591585
[Journal Article] Cancer therapy with local oncolysis and topical cytokine secretion2008
- Author(s)
  Tagawa, M., Kawamura, K., Ueyama, T., Nakamura, M., Tada, Y., Ma, G., Li, Q., Suzuki, N., Shimada, H., Kuriyama, T. and Ochiai, T
- Journal Title
  
  Front. Biosci 13
  
  Pages: 2578-2587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590798
[Journal Article] IL-27-mediated activation of natural killer cells and inflammation produced antitumor effects for human oesophageal carcinoma cells.2008
- Author(s)
  Liu L., Wang S., Shan B., Shao L., Sato A., Kawamura K., Li Q., Ma G., Tagawa M.
- Journal Title
  
  Scand.J.Immunol. 68
  
  Pages: 22-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591585
[Journal Article] Transcriptional regulatory regions of the survivin gene activate an exogenous suicide gene human tumors and enhance the sensitivity to a prodrug.2007
- Author(s)
  Kawamura K., Yu L., Tomizawa M., Shimozato 0., Ma G., Li Q., Sato A., Yang Y., Suzuki T., Abdel-Azizi N.M., Tagawa M.
- Journal Title
  
  Anticancer Res.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590692
[Journal Article] Adenovirus type 5 substituted with type 11 or type 35 fiber structure increases its infectivity to huma cells and enable dualgene transfer in CD46-dependent and -independent manners2007
- Author(s)
  Yu, L., Shimozato, O., Li, Q., Kawamura, K., Ma, G., Namba, M., Ogawa, T., Kaiho, I. And Tagawa, M
- Journal Title
  
  Antican
- Data Source
  KAKENHI-PROJECT-19590798
[Journal Article] The effects of FasL on inflammation and tumor survival are dependent on its2007
- Author(s)
  Wada A., Tada Y, Kawamura K., Takiguchi Y, Tatsumi K., Kuriyama T., Takenouchi T., O-Wang J., Tagawa M.
- Journal Title
  
  Cancer Gene Ther.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590692
[Journal Article] Transcriptional regulatory regions of the survivin gene activate an exogenous suicide gene in human tumors and enhance the sensitivity to a prodrug2007
- Author(s)
  Kawamura, K., Yu, L., Tomizawa, M., Shimozato, O., Ma, G., Li, Q., Sato, A., Yang, Y., Suzuki, T., Abdel-Azizi, N. M., Tagawa, M
- Journal Title
  
  Anticancer Res 27
  
  Pages: 89-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590798
[Journal Article] Virology-and immunology-based gene therapy for cancer2006
- Author(s)
  Tagawa, M
- Journal Title
  
  Anticancer Res. 55
  
  Pages: 1420-1425
- Data Source
  KAKENHI-PROJECT-17590692
[Journal Article] Virology- and immunology-based gene therapy for cancer.2006
- Author(s)
  Tagawa, M
- Journal Title
  
  Cancer Immunol. Immunother. 55
  
  Pages: 1420-1425
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590692
[Journal Article] Role of DNA polymerase θ in tolerance of endogenous and exogenous DNA damage in mouse B cells.2006
- Author(s)
  Ukai A., Maruyama T., Mochizuki S., Ouchida R., Masuda K., Kawamura K., Tagawa M., Kinoshita K., Sakamoto A., Tokuhisa T., O-Wang J.
- Journal Title
  
  Genes to Cells
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590692
[Journal Article] Up-regulated expression of the uridine phosphorylase gene in human gastric tumors is correlated with a favorable prognosis.2006
- Author(s)
  Kawamura K., Takiguchi N., Wada A., Takenobu H., Kimura H., Soda H., Nagata M., Asano T., Tagawa M
- Journal Title
  
  Anticancer Res.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590692
[Journal Article] Virology- and immunology-based gene therapy for cancer.2006
- Author(s)
  Tagawa, Masatoshi
- Journal Title
  
  Cancer Immunol.Immunother. 55
  
  Pages: 1420-1425
- Data Source
  KAKENHI-PROJECT-18591493
[Journal Article] Virology-and immunology-based gene therapy for cancer.2006
- Author(s)
  Tagawa M., Kawamura K., Shimozato 0., Ma G., Li Q., Suzuki N., Shimada H., Ochiai T.
- Journal Title
  
  Cancer Immunol. Immunother.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590692
[Journal Article] DNA polymerase θ contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.2005
- Author(s)
  Masuda K., Ouchida R., Takeuchi A., Saito T., Koseki H., Kawamura K., Tagawa M., Tokuhisa T., Azuma T., O-Wang J.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590692
[Journal Article] Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals.2005
- Author(s)
  Chiyo M, Tagawa M et al.
- Journal Title
  
  Int.J.Cancer 115
  
  Pages: 437-442
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Expression of the fetal-oncogenic fibroblast growth factor-8/17/18 subfamily in human hematopoietic tumors.2005
- Author(s)
  Nezu, M., Tomonaga, T., Sakai, C., Ishii, A., Itoga, S., Nishimura, M., Matsuo, Y., Tagawa, M., Nomura, F.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 335
  
  Pages: 843-849
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells.2005
- Author(s)
  Yu L., Takenobu H., Shimozato 0., Kawamura K., Nimura Y., Seki N., Uzawa K., Tanzawa H., Shimada H., Ochiai T., Tagawa M.
- Journal Title
  
  Oncol. Rep.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590692
[Journal Article] Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals.2005
- Author(s)
  Chiyo, M., Shimozato, O., Yu, L., Kawamura, K., Iizasa, T., Fujisawa, T., Tagawa, M.
- Journal Title
  
  Int.J.Cancer 115
  
  Pages: 437-442
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Up-regulation of the error-prone DNA polymerase x promotes pleiotropic genetic- alterations and tumorigenesis.2005
- Author(s)
  Bavoux, C., Leopoldino, A.M., Bergoglio, V., O-Wang, J., Ogi, T., Bieth, A., Pena, S.D.J., Poupon, M., Helleday, T., Tagawa, M., Machado, C.R., Hoffmann, J., Cazaux, C.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 325-330
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Up-regulation of the error-prone DNA polymerase K promotes pleiotropic genetic alterations and tumorigenesis.2005
- Author(s)
  Bavoux C, Tagawa M et al.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 325-330
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Expression of the fetal-oncogenic fibroblast growth factor-8/17/18 subfamily in human hematopoietic tumors.2005
- Author(s)
  Nezu M, Tagawa M et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun 333
  
  Pages: 843-849
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells.2005
- Author(s)
  Yu, L., Takenobu, H., Shimozato, O., Kawamura, K., Nimura, Y., Seki, N., Ugai, K., Tanzawa, H., Shimada, H., Ochiai, T., Tagawa, M
- Journal Title
  
  Oncol.Rep. 14
  
  Pages: 831-835
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.2005
- Author(s)
  Wada, A., Tada, Y., Shimozato, 0., Takiguchi, Y., Tatsumi, K., Kuriyama, T., Tagawa, M.
- Journal Title
  
  Anticancer Res. 25
  
  Pages: 299-304
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Recombinant Sendai virus vector induces complete remission of established brain tumors through efficient interleukin -2 gene transfer in vaccinated rats.2005
- Author(s)
  Iwadate, Y., Inoue, M., Saegusa, T., Tokusumi, Y., Kinoh, H., Hasegawa, M., Tagawa, M., Yamaura, A., Shimada, H.
- Journal Title
  
  Clin.Cancer Res. 11
  
  Pages: 3821-3827
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells.2005
- Author(s)
  Yu L, Tagawa M et al.
- Journal Title
  
  Oncol.Rep. 14
  
  Pages: 831-835
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] recombinant Sendai virus vector indeces complete remission of established brain tumors trough efficient interleukin-2 gene transfer in vaccinated rats.2005
- Author(s)
  Iwadata Y, Tagawa M etal.
- Journal Title
  
  Clin. Cancer Res. 11
  
  Pages: 3821-3827
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Up-regulation of the error-prone DNA polymerase κ promotes pleiotropic genetic alterations and tumorigenesis.2005
- Author(s)
  Bavoux C, Tagawa M et al.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 325-330
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Recombinant Sendai virus vector induces complete remission of established brain tumors through efficient interleukin-2 gene transfer in vaccinated rats.2005
- Author(s)
  Iwadate Y, Tagawa M et al.
- Journal Title
  
  Clin.Cancer Res. 11
  
  Pages: 3821-3827
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Expression of the fetal-oncogenic fibroblast groeth factor-8/17/18 subfamily in human hematopoietic tumors.2005
- Author(s)
  Nezu M, Tagawa M et al.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 335
  
  Pages: 843-849
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.2005
- Author(s)
  Wada A, Tagawa M et al.
- Journal Title
  
  Anticancer Res 25
  
  Pages: 299-304
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals.2005
- Author(s)
  Chiyo M, Tagawa M et al.
- Journal Title
  
  Int. J Cancer 115
  
  Pages: 437-442
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells.2005
- Author(s)
  Yu L, Tagawa M et al.
- Journal Title
  
  Oncol,Rep. 14
  
  Pages: 831-835
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals.2005
- Author(s)
  Chiyo M., Shimozato 0., Yu L., Kawamura K., Iizasa T., Fujisawa T., Tagawa M.
- Journal Title
  
  Int. J. Cancer
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590692
[Journal Article] The secretion form of the p40 subunit of interleukin (IL)-12 inhibits IL-23 functions and abrogates IL-23-mediated antitumor effects.2005
- Author(s)
  Shimozato O., Ugai S., Chiyo M., Takenobu H., Nagakawa H., Wada A., Kawa mura K., Yamamoto H., Tagawa, M.
- Journal Title
  
  Immunology
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590692
[Journal Article] Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.2005
- Author(s)
  Wada A, Tagawa M et al.
- Journal Title
  
  Anticancer Res. 25
  
  Pages: 299-304
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Expression of interleukin-21 and -23 in human esophageal tumors produced antitumor effects in nude mice.2004
- Author(s)
  Shan, B., Yu, L., Shimozato, O., Li, Q., Tagawa, M.
- Journal Title
  
  Anticancer Res. 24
  
  Pages: 79-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Antitumor effects produced by tranduction of dendritic cells-derived heterodimeric cytokine genes in murne colon carcinoma cells.2004
- Author(s)
  Chiyo M, Tagawa M et al.
- Journal Title
  
  Anticancer Res. 24
  
  Pages: 3763-3768
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Expression of interleukin-21 and -23 in human esphageal tumors produced antitumor sffects in nude mice.2004
- Author(s)
  Shan B, Tagawa M et al.
- Journal Title
  
  Anticaner Res. 24
  
  Pages: 79-82
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Midkine promoter-based conditinally replicative adenovirus for malignant glioma the rapy.2004
- Author(s)
  Kohno S, Tagawa M et al.
- Journal Title
  
  Oncol Rep. 12
  
  Pages: 73-78
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Midkine promoter can mediate transcriptional activation of a fused suicide gene in a broader range of human breast cancer compared with c-erdB-2 promoter.2004
- Author(s)
  Yu L, Tagawa M et al.
- Journal Title
  
  Oncology 66
  
  Pages: 143-146
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Elevated expression of DNA polymerase x expression in human lung cancer is associated with p53 inactivation: Negative regulation of POLKpromoter activity by p53.2004
- Author(s)
  Wang, Y.Q., Seimiya, M., Kawamura, K., Yu, L., Ogi, T., Takenaga, K., Shishikura, T., Nakagawara, A., Sakiyama, S., Tagawa, M., O-Wang, J.
- Journal Title
  
  Int.J.Oncol. 25
  
  Pages: 161-165
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Expression of CD40 ligand in CD40-positive murine tumors activates transcription of the interleukin-23 subunit genes and produces antitumor responses.2004
- Author(s)
  Wada, A., Tada, Y., Shimozato, O., Takiguchi, Y., Tatsumi, K., Kuriyama, T., Tagawa, M.
- Journal Title
  
  Anticancer Res. 24
  
  Pages: 2713-2716
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] DNA polymerase θ is preferentially expressed in lymphoid tissues and upregulated in human cancers.2004
- Author(s)
  Kawamura, K., Bahar, R., Seimiya, M., Chiyo, M., Wada, A., Okada, S., Hatano, M., Tokuhisa, T., Kimura, H., Watanabe, S., Honda, I., Sakiyama, S., Tagawa, M., O-Wang, J.
- Journal Title
  
  Int.J.Cancer 109
  
  Pages: 9-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] Expression of the interleukin-21 and -23 in human esophageal tumors Produced antitumor effects in nude mice.2004
- Author(s)
  Shan B., Yu L., Shimozato O., Li Q., Tagawa M.
- Journal Title
  
  Anticancer Res 24
  
  Pages: 79-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370377
[Journal Article] A Cox-2 promoter-based replication-selective adenovital vector to target the Cox-2-expressing human bladder cancer cells.2004
- Author(s)
  shirakawa T, Tagawa M et al.
- Journal Title
  
  Clin. Cancer Res. 10
  
  Pages: 4342-4348
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Midkine promoter-driven suicide gene expression and-mediated adenovirus replication produced cytotoxic effects to immortalized and tumour cells.2004
- Author(s)
  Yu, L., Hamada, K., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S., Tagawa, M.
- Journal Title
  
  Eur.J.Cancer 40
  
  Pages: 1787-1794
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] Insertion of an exogenous promoter in the E1A regulatory region of adenovirus does not disturb viral replication despite reduced E1 A transcription.2004
- Author(s)
  Yu, L., Hamada, K., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S., Tagawa, M.
- Journal Title
  
  Cancer Lett. 203
  
  Pages: 51-57
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] Expression of the interleukin-21 and -23 in human esophageal tumors produced Antitumor effects in nude mice.2004
- Author(s)
  Shan B., Yu L., Shimozato O., Li Q., Tagawa M.
- Journal Title
  
  Anticancer Res 24
  
  Pages: 79-82
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370377
[Journal Article] Expression of interleukin-22 in murine carcinoma cells did not influence tumor growth in vivo but did improve the survival of inoculated hosts.2004
- Author(s)
  Nagakawa, H., Shimozato, O., Yu, L., Takiguchi, Y., Tatsumi, K., Kuriyama, T., Tagawa, M.
- Journal Title
  
  Scand.J.Immunol. 60
  
  Pages: 449-454
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Midkine promoter-driven suicide gene expression and -mediated adenovirus replication produced cytotoxic effects to immortalized and tumour cells.2004
- Author(s)
  Yu, L., Hamada, K., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S., Tagawa, M.
- Journal Title
  
  Eur.J.Cancer 40
  
  Pages: 1787-1794
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Midkine promoter can mediate transcriptional activation of a fused suicide gene in a broader range of human breast cancer compared with c-erbB-2 promoter.2004
- Author(s)
  Yu, L., Yamamoto, N., Kadomatsu, K., Muramatsu, T., Matsubara, S., Sakiyama S., Tagawa, M.
- Journal Title
  
  Oncology 66
  
  Pages: 143-146
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] A Cox-2 promoter-based replication-selective adenoviral vector to target the Cox-2-expressing human bladder cancer cells.2004
- Author(s)
  Shirakawa, T., Hamada, K., Zhang, Z., Okada, H., Tagawa, M., Kamidono, S., Kawabata, M., Gotoh, A.
- Journal Title
  
  Cancer Res. 10
  
  Pages: 4342-4348
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Correlation between interleukin 6 production and tumor proliferation in non-small cell lung cancer.2004
- Author(s)
  Yamaji, H., Iizasa, T., Koh, E., Suzuki, M., Otsuji, M., Chang, H., Motohashi, S., Yokoi, S., Hiroshima, K., Tagawa, M., Nakayama, T., Fujisawa T.
- Journal Title
  
  Cancer Immunol.Immunother. 53
  
  Pages: 786-792
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Expression of interleukin-22 in murine carcinoma cells did not influence tumor groeth in vivo but did improve the survival of inoculated hosts.2004
- Author(s)
  Nagakawa H, Tagawa M et al.
- Journal Title
  
  Scand. J. Immunol. 60
  
  Pages: 449-454
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Impaired lymphocyte development and function in Clast5/Stra13/DEC1 transgenic mice.2004
- Author(s)
  Seimiya, M., Wada, A., Kawamura, K., Sakamoto, A., Ohkubo, Y., Okada, S., Hatano, M., Tokuhisa, T., Watanabe, T., Saisho, H., Tagawa, M., O-Wang, J.
- Journal Title
  
  Eur.J.Immunol. 34
  
  Pages: 1322-1332
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Insertion of an exogenous promoter in the E1A regulatory region of adenovirus does not disturb viral replication despite reduced E1A transcription.2004
- Author(s)
  Yu, L., Hamada, K., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S., Tagawa, M.
- Journal Title
  
  Cancer Lett. 203
  
  Pages: 51-57
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Midkine promoter-driven suicide gene expression and -mediated adenovirus replication produced cytotoxic effects to immortalizad and tumour calls2004
- Author(s)
  Yu L, Tagawa M et al.
- Journal Title
  
  Eur.J.Cancer 40
  
  Pages: 1787-1794
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Insertion of an exogenous progenous promoter in the E1A regulatory of adenovirus dose not disturb viral replication despote reduced E1A transcription.2004
- Author(s)
  Yu L, Tagawa M et al.
- Journal Title
  
  Cancer Lett. 203
  
  Pages: 51-57
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Antitumor effects produced by tranduction of dendritic cells-derived heterodimeric cytokine genes in murine colon carcinoma cells.2004
- Author(s)
  Chiyo, M., Shimozato, O., Iizasa, T., Fujisawa, T., Tagawa, M.
- Journal Title
  
  Anticancer Res. 24
  
  Pages: 3763-3768
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Elevated expression of DNA polymerase κ expression in human lung cancer is associated with p53 inactivation : Negative regulation of POLK promoter activity by p53.2004
- Author(s)
  Wang, Y.Q., Seimiya, M., Kawamura, K., Yu, L., Ogi, T., Takenaga, K., Shishikura, T., Nakagawara, A., Sakiyama, S., Tagawa, M., O-Wang, J.
- Journal Title
  
  Int.J.Oncol. 25
  
  Pages: 161-165
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] Midkine promoter can mediate transcriptional activation of a fused suicide gene in a broader range of human breast cancer compared with c-erbB-2 promoter.2004
- Author(s)
  Yu, L., Yamamoto, N., Kadomatsu, K., Muramatsu, T., Matsubara, S., Sakiyama S., Tagawa, M.
- Journal Title
  
  Oncology 66
  
  Pages: 143-146
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Correlation between interleukin 6 production and tumor proliferation in non-small cell ling2004
- Author(s)
  Yamaji H, Tagawa M et al.
- Journal Title
  
  Cancer Immunol. Immunother. 53
  
  Pages: 786-792
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Midkine promoter-based conditionally replicative adenovirus for malignant glioma therapy.2004
- Author(s)
  Kohno, S., Nakagawa, K., Hamada, K., Harada, H., Yamasaki, K., Hashimoto, K., Tagawa, M., Nagato, S., Furukawa, K., Ohnishi, T.
- Journal Title
  
  Oncol Rep. 12
  
  Pages: 73-78
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591381
[Journal Article] Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts.2003
- Author(s)
  Ugai S, Shimozato O, Kawamura K, Wang YQ, Yamaguchi T, Saisho H, Sakiyama S., Tagawa M.
- Journal Title
  
  Cancer Gene Ther. 10
  
  Pages: 187-192
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370377
[Journal Article] Regulatory regions of growth-related genes can activate an exogenous gene of the α-fetoprotein promoter to a comparable degree in human hepatocellular carcinoma cells.2003
- Author(s)
  Tomizawa, M., Saisho, H., Tagawa, M.
- Journal Title
  
  Anticancer Res. 23
  
  Pages: 3273-3277
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] Stage-specific expression of Clast6/E3/LAPTM5 during B cell differentiation : elevated expression in human B lymphomas.2003
- Author(s)
  Seimiya, M., O-Wang, J., Bahar, R., Kawamura, K., Wang, Y., Saisho, H., Tagawa, M.
- Journal Title
  
  Int.J.Oncol. 22
  
  Pages: 301-304
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] Fas ligand-expressing tumors induce tumor-specific protective mmunity in the inoculated hosts but vaccination with the apoptotic tumors suppresses antitumor immunity.2003
- Author(s)
  Tada, Y., O-Wang, J., Wada, A., Takiguchi, Y., Tatsumi, K., Kuriyama, T., Sakiyama, S., Tagawa, M.
- Journal Title
  
  Cancer Gene Ther. 10
  
  Pages: 134-140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] Cell growth- and P53-dependent transcriptional activity of the midkine promoter confers suicide gene expression in tumor cells.2003
- Author(s)
  Yu, L., Ugai, S., O-Wang, J., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S., Sakiyama, S., Tagawa, M.
- Journal Title
  
  Oncol.Rep. 10
  
  Pages: 1301-1305
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma.2003
- Author(s)
  Shimada H, Nabeya Y, Tagawa M, Okazumi S, Matsubara H, Ochiai T., et al.
- Journal Title
  
  Cancer Sci. 94・7
  
  Pages: 628-632
- NAID
  10011688973
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370377
[Journal Article] Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts.2003
- Author(s)
  Ugai, S., Shimozato, O., Kawamura, K., Wang, Y-Q., Yamaguchi, T., Saisho, H., Sakiyama, S, Tagawa, M.
- Journal Title
  
  Cancer Gene Ther. 10
  
  Pages: 187-192
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma.2003
- Author(s)
  Shimada H, Nabeya Y, Tagawa M, Okazumi S, Matsubara H, Ochiai T., et al.
- Journal Title
  
  Cancer Sci 94
  
  Pages: 628-632
- NAID
  10011688973
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370377
[Journal Article] Down-regulated expression of CCAAT/enhancer binding protein α and β genes in human hepatocellular carcinoma : a possible prognostic marker.2003
- Author(s)
  Tomizawa, M., Watanabe, K., Saisho, H., Nakagawara, A., Tagawa, M.
- Journal Title
  
  Anticancer Res. 23
  
  Pages: 351-354
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590706
[Journal Article] Cytotoxicity of adenoviruses expressing the wild-type p53 gene to esophageal carcinoma cells is linked with the CAR expression level and indirectly with the endogenous
- Author(s)
  Ma, G., Kawamura, K., Li, Q., Suzuki, N., Liang, M., Namba, M., Shimada, H. and Tagawa, M
- Journal Title
  
  Cancer Gene Ther (in press)
  
  Pages: 53-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590798
[Presentation] 核酸合成酵素非依存的なペメトレキセート耐性はAICARTを介したAMPKの活性化に関与している2018
- Author(s)
  鐘博雅、関根郁夫、滝口裕一、グエン　タオ、盛永敬郎、多田裕司、山口直人、田川雅敏
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10617
[Presentation] Cytotoxicity of Replication-Competent Adenoviruses Defective of E1B55kDa Molecules Is Irrelevant to P53 Expression, but Increases with a P53-Augmenting MDM2 Inhibitor through DNA Damages and Enhanced Viral Propagations in Mesothelioma with the Wild-Type P53 Genotype2018
- Author(s)
  Thao Thi Thanh Nguyen, Takao Morinaga, Boya Zhong, Shuji Kubo, Masato Shingyoji, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
- Organizer
  21st annual meeting of American Society of Gene and Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09598
[Presentation] HSP90阻害剤は内因性p53発現を上昇させるが外因性p53発現をプロテアソーム活性で抑制する2018
- Author(s)
  田川雅敏、盛永敬郎、鐘博雅、Nguyen Thi Thanh Thao、久保秀司、多田裕司、巽浩一郎、島田英昭、廣島健三、山口直人
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10617
[Presentation] An MDM2 inhibitor achieves synergistic cytotoxicity with oncolytic adenoviruses on mesothelioma with the wild-type p53 gene.2018
- Author(s)
  Masatoshi Tagawa, Thao Thi Thanh Nguyen, Takao Morinaga, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
- Organizer
  The 14th international conference of the international mesothelioma interested group
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09598
[Presentation] A role of Wee1 kinase in adenoviruses-induced cell death and viral replication2017
- Author(s)
  盛永敬郎、グエン　タオ、鐘博雅、久保秀司、関根郁夫、多田裕司、巽浩一郎、島田英昭、廣島健三、田川雅敏
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10617
[Presentation] An inhibitor for the MDM2-p53 Interaction Produces Synergistic Cytotoxicity with Oncolytic Adenoviruses on Mesothelioma with Wild-type p53 Genotype2017
- Author(s)
  Masatoshi Tagawa, Thao Thi Thanh Nguyen, Takao Morinaga, Boya Zhong, Michiko Hanazono, Shuji Kubo, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
- Organizer
  20th annual meeting of American Society of Gene and Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09598
[Presentation] 悪性中皮腫におけるペメトレキセド耐性はAMPKの活性化が関与する2017
- Author(s)
  鐘博雅、関根郁夫、滝口裕一、グエン・タオ、盛永敬郎、多田裕司、山口直人、田川雅敏
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-26461183
[Presentation] A MDM2 inhibitor augments cytotoxicity of oncolytic adenoviruses defective of E1B 55kDa molecules through enhancing DNA damages and apoptosis in mesothelioma2017
- Author(s)
  Masatoshi Tagawa, Thao Thi Thanh Nguyen, Takao Morinaga, Boya Zhong, Michiko Hanazono, Shuji Kubo, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
- Organizer
  23rd annual meeting of Japan Society of Gene Therapy
- Data Source
  KAKENHI-PROJECT-16K09598
[Presentation] A Wee1 kinase inhibitor increases apoptosis of replication-competent adenoviruses through induction of mitotic catastrophe and enhancement of viral replications2017
- Author(s)
  Takao Morinaga, Thao Thi Thanh Nguyen, Boya Zhong, Shuji Kubo, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
- Organizer
  23rd annual meeting of Japan Society of Gene Therapy
- Data Source
  KAKENHI-PROJECT-17K10617
[Presentation] Enhanced expression of endogenous p53 contributes to E1B55-defective adenoviruses-induced cell death of mesothelioma deleted in the INK4a/ARF region2016
- Author(s)
  Yuji Tada, Thi Thanh Thao Nguyen, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
- Organizer
  Tenth international meeting on replicating oncolytic virus therapeutics
- Place of Presentation
  Vancouver（Canada）
- Year and Date
  2016-10-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09598
[Presentation] Combination of nutlin-3a and HSP90 inhibitors produces synergistic cytotoxicity on mesothelioma with the wild-type p532016
- Author(s)
  Masatoshi Tagawa, Shinya Okamoto, Takao Morinaga, Masato Shingyoji, Ikuo Sekine, Toshio Suzuki, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
- Organizer
  The 13th international conference of the international mesothelioma interested group
- Place of Presentation
  Birmingham（UK）
- Year and Date
  2016-05-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09598
[Presentation] 細胞周期促進は増殖性アデノウイルスによるアポトーシスを増強する2016
- Author(s)
  盛永敬郎, グエンタオ, チョンボウヤア, 久保秀司, 関根郁夫, 多田裕司, 巽浩一郎, 島田英昭, 廣島健三, 田川雅敏
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26462000
[Presentation] MDM2 and MDM4 inhibitors in combination with adenoviruses up-regulating p53 produce synergistic anti-tumor effects on mesothelioma through augmenting apoptotic processes2016
- Author(s)
  Masatoshi Tagawa, Taka-aki Kozono, Yiyang Qin, Xue Rao Ning, Takao Morinaga, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
- Organizer
  22th annual meeting of Japan Society of Gene Therapy
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京）
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-26462000
[Presentation] Enhanced expression of endogenous p53 contributes to E1B55-defective adenoviruses-induced cell death of mesothelioma deleted in the INK4a/ARF region2016
- Author(s)
  Yuji Tada, Thi Thanh Thao Nguyen, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
- Organizer
  Tenth international meeting on replicating oncolytic virus therapeutics
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2016-10-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461183
[Presentation] E1B-55kDa-defective adenoviruses produced cytotoxicity in combination with MDM2 inhibitors on INK4A/ARF-defective mesothelioma2016
- Author(s)
  Yuji Tada, Thi Thanh Thao Nguyen, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
- Organizer
  2016 ESGCT and ISSCR Congress
- Place of Presentation
  Florence, Italy
- Year and Date
  2016-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461183
[Presentation] MDMX阻害剤の悪性中皮腫に対する細胞傷害活性はp53非依存的であるが、MDM2阻害剤とは相乗的な併用効果を示すA MDMX inhibitor produces cytotoxicity in a p53-independent manner but achieves synergistic actions with MDM2 inhibitors2016
- Author(s)
  田川雅敏、盛永敬郎、チョンボウヤア、グエンタオ、久保秀司、関根郁夫、多田裕司、巽浩一郎、島田英昭、廣島健三
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市神奈川県）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461183
[Presentation] Combination of nutlin-3a and HSP90 inhibitors produces synergistic cytotoxicity on mesothelioma with the wild-type p53.2016
- Author(s)
  Masatoshi Tagawa, Shinya Okamoto, Takao Morinaga, Masato Shingyoji, Ikuo Sekine, Toshio Suzuki, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
- Organizer
  The 13th international conference of the international mesothelioma interested group
- Place of Presentation
  Birmingham, UK
- Year and Date
  2016-05-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461183
[Presentation] Combination of Forced Transduction of P53 and an Agent That Blocks MDM2-p53 Interactions Produces Synergistic Cytotoxicity on Mesothelioma Defective of the INK4A/ARF Region2016
- Author(s)
  Masatoshi Tagawa, Takao Morinaga, Zhihan Li, Thao Thi Thanh Nguyen, Boya Zhong, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
- Organizer
  19th annual meeting of American Society of Gene and Cell Therapy
- Place of Presentation
  Washington DC, USA
- Year and Date
  2016-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461183
[Presentation] MDM2 and MDM4 inhibitors in combination with adenoviruses up-regulating p53 produce synergistic anti-tumor effects on mesothelioma through augmenting apoptotic processes2016
- Author(s)
  Masatoshi Tagawa, Taka-aki Kozono, Yiyang Qin, Xue Rao Ning, Takao Morinaga, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
- Organizer
  22th annual meeting of Japan Society of Gene Therapy
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2016-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461183
[Presentation] Heat shock protein 90 inhibitors augment endogenous p53 in p53 wild-type tumors but suppress Ad-mediated over-expressed exogenous p53 levels.2015
- Author(s)
  Masatoshi Tagawa, Shinya Okamoto, Takao Morinaga, Taka-Aki Kozono, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
- Organizer
  21th annual meeting of Japan Society of Gene Therapy
- Place of Presentation
  大阪市
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-26462000
[Presentation] 悪性中皮腫細胞に対してHSP90 阻害剤はAKT とMDMX 活性を阻害し、Nutlin-3a と相乗的な抗腫瘍効果を示す2015
- Author(s)
  李知瀚、岡本慎也、盛永敬郎、江媛媛、久保秀司、関根郁夫、滝口裕一、多田裕司、巽浩一郎、島田英昭、廣島健三、田川雅敏
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26461183
[Presentation] Cytotoxicity by Adenovirus Replications is Associated with DNA Damages and the Activated P53 Pathways and is Dependent on Reactive Oxygen Species.2015
- Author(s)
  Masatoshi Tagawa, Kiyoko Kawamura, Shinya Okamoto, Yuanyuan Jiang, Zhihan Li, Takao Morinaga, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
- Organizer
  18th annual meeting of American Society of Gene and Cell Therapy
- Place of Presentation
  New Orleans, USA
- Year and Date
  2015-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462000
[Presentation] アデノウイルス製剤を用いた悪性中皮腫に対する遺伝子治療の実施にむけて2014
- Author(s)
  田川雅敏, 多田裕司、新行内雅斗，由佐俊和，島田英昭，廣島健三，巽浩一郎
- Organizer
  第21回石綿・中皮腫研究会
- Place of Presentation
  名古屋市熱田区
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-24591185
[Presentation] Anti-tumor effects of Ad-p53 on INK4A/ARF-defective mesothelioma are influenced positively by small G protein inhibitors but negatively by heat shock protein 90 inhibitors.2013
- Author(s)
  Masatoshi Tagawa, Kuan Chai, Yuanyuan Jiang, Kiyoko Kawamura, Shan Yang, Atsushi Ogino, Naoto Yamaguchi, Kazunori Kato, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima and Shuji Kubo
- Organizer
  16th annual meeting of American Society of Gene and Cell Therapy
- Place of Presentation
  Salt Lake City, USA
- Data Source
  KAKENHI-PROJECT-24591185
[Presentation] Cytotoxicity of replication-competent adenoviruses are enhanced by co-transduced p53 gene.2013
- Author(s)
  Masatoshi Tagawa, Shan Yang, Kiyoko Kawamura, Shinya Okamoto, Shuji Kubo, Yuji Tada, Kenzo Hiroshima, Hideaki Shimada
- Organizer
  21th Annual Congress of the European Society of Gene and Cell Therapy
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-24591185
[Presentation] A Cancer-targeting ligand strongly enhances oncolytic activity of a conditionally replicative adenovirus.2013
- Author(s)
  Yuki Yamamoto, Naoko Goto, Shumpei Ohnami, Masatoshi Tagawa and Kazunori Aoki
- Organizer
  16th annual meeting of American Society of Gene and Cell Therapy
- Place of Presentation
  Salt Lake City, USA
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Updated gene therapy for malignant mesothelioma: Challenges for the intractable caner.2013
- Author(s)
  Masatoshi Tagawa, Yuji Tada, Hideaki Shimada and Kenzo Hiroshima
- Organizer
  19th annual meeting of Japan Society of Gene Therapy
- Place of Presentation
  Okayama, Japan
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Oncolytic effects of a fiber knob substituted adenovirus vector to human lung cancer cells2013
- Author(s)
  Nagaya H, Kanno T, Hiwasa K, Nakagawa Y, Shimomura K, Nakano T, Nishizaki T, Tagawa M, Gotoh A
- Organizer
  第19回日本遺伝子治療学会年次学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23592354
[Presentation] Updated gene therapy for malignant mesothelioma : Challenges for the intractable caner2013
- Author(s)
  Masatoshi Tagawa, その他
- Organizer
  19th annual meeting of Japan Society of Gene Therapy
- Place of Presentation
  Okayama
- Year and Date
  2013-07-06
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Oncolytic effects of a fiber knob substituted adenovirus vector to human lung cancer cells.2013
- Author(s)
  Nagaya H, Kanno T, Hiwasa K, Nakagawa Y, Shimomura K, Nakano T, Nishizaki T, Tagawa M, Gotoh A
- Organizer
  第19回日本遺伝子治療学会年次学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23592354
[Presentation] An HSP90 inhibitor, which blocks p53 degradation, suppresses adenoviruses-mediated p53 production and the apoptosis2013
- Author(s)
  柴寛、荻野敦史、多田裕司、関根郁夫、滝口裕一、巽浩一郎、島田英昭、廣島健三、加藤和則、山口直人、田川雅敏
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Midkine promoter-driven oncolytic adenovirus with Ad35 fiber modification achieves enhanced transduction of human osteosarcoma cells.2013
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Atsuko Tamamoto, Nobutaka Okamura, Masatoshi Tagawa, Noriyuki Kasahara, Haruki Okamura and Tomoko Hashimoto-Tamaoki
- Organizer
  19th annual meeting of Japan Society of Gene Therapy
- Place of Presentation
  Okayama, Japan
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Activation of p53 pathways produces combinatory effects with chemotherapeutic agents on p53 wild-type mesothelioma.2013
- Author(s)
  Masatoshi Tagawa, Kiyoko Kawamura, Shan Yang, Yuanyuan Jiang, Kuan Chai, Naoto Yamaguchi, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada and Kenzo Hiroshima
- Organizer
  19th annual meeting of Japan Society of Gene Therap
- Place of Presentation
  Okayama
- Data Source
  KAKENHI-PROJECT-24591185
[Presentation] Development of doubly regulated oncolytic adenovirus for human malignant mesothelioma.2013
- Author(s)
  Shuji Kubo, Misato Takagi-Kimura, Atsuko Tamamoto, Tomoko Hashimoto-Tamaoki, Noriyuki Kasahara and Masatoshi Tagawa
- Organizer
  16th annual meeting of American Society of Gene and Cell Therapy
- Place of Presentation
  Salt Lake City, USA
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Cytotoxicity of replication-competent adenoviruses in esophageal carcinoma was enhanced by forced p53 expression.2012
- Author(s)
  楊珊、川村希代子、江媛媛、柴　寛、久保秀司、山口直人、多田裕司、滝口裕一、巽浩一郎、島田英昭、廣島健三、田川雅敏
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] A small G protein inhibitor, bisphosphonates, produces synergistic cytotoxicity on wild-type p53-bearing mesothelioma with adenoviruses up-regulating the p53 expression level.2012
- Author(s)
  Masatoshi Tagawa, Kiyoko Kawamura, Shinya Okamoto, Jiang Yuan Yuan, Masato Shingyoji, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima.
- Organizer
  20th Annual Congress of the European Society of Gene and Cell Therapy
- Place of Presentation
  ベルサイユ、フランス
- Data Source
  KAKENHI-PROJECT-24591185
[Presentation] Oncolytic effects of a fiber knob substituted adenovirus vector to human bladder carcinoma cells.2012
- Author(s)
  Nagaya H, Terao S, Hiwasa K, Tagawa M, Gotoh A.
- Organizer
  第18回日本遺伝子治療学会年次学術集会
- Place of Presentation
  ホテル熊本テルサ（熊本）
- Data Source
  KAKENHI-PROJECT-23592354
[Presentation] 腎癌細胞株に対するファイバー改変アデノウイルスベクターによるin vitroでの抗腫瘍効果の検討2012
- Author(s)
  長屋寿雄、寺尾秀治、日和佐一弘、田川雅敏、後藤章暢
- Organizer
  第21回　泌尿器科分子・細胞研究会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23592354
[Presentation] Gene therapy for malignant mesothelioma with restored p53 functions.2012
- Author(s)
  Masatoshi Tagawa, Kiyoko Kawamura, Shan Yang, Yuanyuan Jiang, Kuan Chai, Naoto Yamaguchi, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima.
- Organizer
  Internatinal Socieity for Cell and Gene Therapy of Cancer 2012
- Place of Presentation
  シンガポール
- Invited
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Zoledronic acid, the third generation of bisphosphonates, produces anti-tumor effects on mesothelioma in vitro and in vivo through apoptosis or S phase arrest in p53-independent and Ras prenylation-independent manners.2012
- Author(s)
  Yuji Tada, Quanhai Li, Kiyoko Kawamura, Hiroshi Kobayashi, Ikuo Sekine, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa.
- Organizer
  The11th international conference of the international mesothelioma interested group
- Place of Presentation
  ボストン、米国
- Data Source
  KAKENHI-PROJECT-24591185
[Presentation] Reactivation of p53-mediated pathways induces apoptosis in mesothelioma with wild-type p53 gene and produces combinatory synergistic effects with anti-cancer agents.2012
- Author(s)
  Masatoshi Tagawa, Quanhai Li, Kiyoko Kawamura, Masato Shingyoji, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima.
- Organizer
  The11th international conference of the international mesothelioma interested group
- Place of Presentation
  ボストン、米国
- Data Source
  KAKENHI-PROJECT-24591185
[Presentation] Bisphosphonates induce apoptosis through the suppression of Rab and produce combinatory effects with anti-cancer agents2012
- Author(s)
  田川雅敏, その他
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Analysis of serum anti-galectin-1 antibody in stage I/II gastroenterological carcinomas.2012
- Author(s)
  島田英昭、谷島　聡、小池淳一、田川雅敏、日和佐隆樹、松下一之、野村文夫
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Bisphosphonates induce apoptosis through the suppression of Rab and produce combinatory effects with anti-cancer agents.2012
- Author(s)
  田川雅敏、川村希代子、楊珊、江媛媛、柴　寛、久保秀司、山口直人、多田裕司、滝口裕一、巽浩一郎、島田英昭、廣島健三
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Gene therapy for malignant mesothelioma with restored p53 functions2012
- Author(s)
  Masatoshi Tagawa, その他
- Organizer
  International Society for Cell and Gene Therapy of Cancer2012 Singapore Conference
- Place of Presentation
  Singapore
- Year and Date
  2012-10-05
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Development of doubly regulated oncolytic adenovirus for human malignant mesothelioma.2012
- Author(s)
  久保秀司、山野智基、吉川良恵、森永伴法、玉置知子、田川雅敏、笠原典之
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Up-regulated p53 expression activates apoptotic pathways in wild-type p53-bearing mesothelioma and enhances cytotoxicity of the first-line chemotherapeutic agents2011
- Author(s)
  Masatoshi Tagawa, その他
- Organizer
  19th Annual Congress of the European Society of Gene and Cell Therapy
- Place of Presentation
  Brighton, UK
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Promoter-mediated replication of adenoviruses induces apoptosis-independent cell death in p53-null pancreatic carcinoma cells.2011
- Author(s)
  Tagawa, M., その他
- Organizer
  14th annual meeting of American Society of Gene and Cell Therapy
- Place of Presentation
  シアトル、アメリカ
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] 制限増殖型アデノウイルスは、膵がん細胞においてアポトーシス、オートファジー非依存的な細胞死を誘導する2011
- Author(s)
  山内駿、川村希代子、岡本慎也、楊珊、江媛媛、深町利彦、小林弘、多田裕司、巽浩一郎、島田英昭、廣島健三、田川雅敏
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21590879
[Presentation] Up-regulated p53 expression activates apoptotic pathways in wild-type p53-bearing mesothelioma and enhances cytotoxicity of the first-line chemotherapeutic agents.2011
- Author(s)
  Tagawa, M., その他
- Organizer
  19th Annual Congress of the European Society of Gene and Cell Therapy
- Place of Presentation
  ブライトン、英国
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] Promoter-mediated replication of adenoviruses induces apoptosis-independent cell death in p53-null pancreatic carcinoma cells2011
- Author(s)
  Masatoshi Tagawa, その他
- Organizer
  14th annual meeting of American Society of Gene and Cell Therapy
- Place of Presentation
  Seattle、USA
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23591951
[Presentation] IL-17は血管内皮細胞のフラクタルカインの発現を増強することにより腫瘍の肺転移を抑制する2010
- Author(s)
  藤江瞳, 田川雅敏, 沼崎宗夫
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪府大阪市・大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22590869
[Presentation] インターフェロンラムダ発現型アデノウイルスによる食道がんに対する抗腫瘍効果2010
- Author(s)
  田川雅敏, 川村希代子, 岡本慎也, 楊珊, 深町利彦, 小林弘, 藤江瞳, 沼崎宗夫, 島田英昭
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪府大阪市・大阪国際会議場
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22590869
[Presentation] 悪性中皮腫における細胞融解性アデノウイルス感受性の検討2010
- Author(s)
  川村希代子、岡本慎也、深町利彦、小林弘、楊珊、久保秀司、山中満佳子、多田裕司、巽浩一郎、島田英昭、廣島健三、田川雅敏
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21590879
[Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda produced anti-tumor effects to human esophageal carcinoma in vivo.2010
- Author(s)
  田川雅敏, et al
- Organizer
  13th annual meeting of American Society of Gene and Cell Therapy
- Place of Presentation
  Washington DC
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-20591585
[Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda produced anti-tumor effects to human esophageal carcinoma in vivo.2010
- Author(s)
  Masatoshi Tagawa, Quanhai Li, Kiyoko Kawamura, Shinya Okamoto, Shan Yang, Hiroshi Kobayashi, Muneo Numasaki, Yuji Tada, Kenzo Hiroshima, Hideaki Shimada.
- Organizer
  ASGCT 2010 Clinical Trials Training Course and 13th Annual Meeting
- Place of Presentation
  Mariott Wardman Park Hotel, Washington, DC, USA
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-22590869
[Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda produced anti-tumor effects to human esophageal carcinoma in vivo2010
- Author(s)
  Msatoshi Tagawa 、 Quanhai Li 、 Kiyoko Kawamura 、 Shinya Okamoto 、 Shan Yang 、Hiroshi Kobayashi 、Muneo Numasaki 、Yuji Tada、 Kenzo Hiroshima、 and Hideaki Shimada
- Organizer
  ASGCT 2010 Clinical Trials Training Course and 13th Annual Meeting
- Place of Presentation
  アメリカ
- Data Source
  KAKENHI-PROJECT-22590869
[Presentation] IL-17 は血管内皮細胞のフラクタルカインの発現を増強することにより腫瘍の肺転移を抑制する2010
- Author(s)
  藤江瞳、田川雅敏、沼崎宗夫
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590869
[Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda achieve anti-tumor effects in vivo2010
- Author(s)
  Msatoshi Tagawa 、 Quanhai Li 、 Kiyoko Kawamura、 Shinya Okamoto、 Shan Yang、 Hitomi Fujie 、Muneo Numasaki 、Hideaki Shimada 、and Hiroshi Kobayashi
- Organizer
  第16回日本遺伝子治療学会
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-22590869
[Presentation] インターフェロンラムダ発現型アデノウイルスによる食道がんに対する抗腫瘍効果2010
- Author(s)
  田川雅敏、川村希代子、岡本慎也、楊珊、深町利彦、小林弘、藤江瞳、沼崎宗夫、島田英昭
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590869
[Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda achieve anti-tumor effects in vivo.2010
- Author(s)
  Msatoshi Tagawa, Quanhai Li, Kiyoko Kawamura, Shinya Okamoto, Shan Yang, Hitomi Fujie, Muneo Numasaki, Hideaki Shimada, Hiroshi Kobayashi
- Organizer
  第16回日本遺伝子治療学会
- Place of Presentation
  栃木県宇都宮市・栃木県総合文化センター
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-22590869
[Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda produced anti-tumor effects to human esophageal carcinoma in vivo.2010
- Author(s)
  Tagawa M., et al.
- Organizer
  13th annual meeting of American Society of Gene and Cell Therapy
- Place of Presentation
  Washington DC,USA
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-20591585
[Presentation] インターフェロンーラムダ発現型アデノウイルスによる食道がんに対する抗腫瘍効果2010
- Author(s)
  田川雅敏、他
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20591585
[Presentation] Chimeric adenoviruses with the type 35 fiber-knob structure produce better cytotoxic effects to various human tumors with down-regulated coxsackievirus and adenovirus receptors2009
- Author(s)
  Tagawa, M., et al.
- Organizer
  12th annual meeting of American Society of Gene Therapy
- Place of Presentation
  San Diego、USA
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-20591585
[Presentation] 制限増殖型アデノウイルスに対する腫瘍細胞の感受性を決定する因子の検討2009
- Author(s)
  川村希代子、李全海、武井優輝、山口直人、藤森浩中、多田裕司、山中満佳子、滝口裕一、巽浩一郎、廣島健三、島田英昭、田川雅敏
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21590879
[Presentation] Chimeric adenoviruses with the type 35 fiber-knob structure produce better cytotoxic effects to various human tumors with down-regulated coxsackievirus and adenovirus receptors.2009
- Author(s)
  田川雅敏, et al
- Organizer
  12th annual meeting of American Society of Gene Therapy
- Place of Presentation
  San Diego
- Year and Date
  2009-05-29
- Data Source
  KAKENHI-PROJECT-20591585
[Presentation] Therapeutic efficacy of midkine promoter-based conditionally replicative adenovirus vector for targeting the midkine-expressing human bladder cancer cells.2008
- Author(s)
  Terao S, Shirakawa, T., Acharya, B., Suzuki, T., Hamada, K., Tagawa, M., Tanaka, K., Takenaka, A., Fujisawa, M., Gotoh A
- Organizer
  2008 International Society for Cell and Gene Therapy of Cancer China Conference
- Place of Presentation
  Shijiazhuang, China
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20591871
[Presentation] Type 5 adenoviruses bearing the type 35-derived fiber-knob region enhanced the infectivity and increased the anti-tumor effects to CAR-low expressing tumors.2008
- Author(s)
  田川雅敏, et al
- Organizer
  16th Annual Congress of the European Society of Gene and Cell Therapy
- Place of Presentation
  Brugge, Belgium
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-20591585
[Presentation] アデノウイルスによる腫瘍細胞死に対して影響を与える細胞因子の検討2008
- Author(s)
  川村希代子、馬光宇、李全海、植山太郎、廣島健三、島田英昭、多田裕司、滝口裕一、巽浩一郎,栗山喬之、田川雅敏
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19590798
[Presentation] ヒト膀胱癌細胞に対するミドカインプロモーターを組み込んだ増殖制限型アデノウイルスベクター(ADMKE1a)の有用性の検討2008
- Author(s)
  寺尾秀治,白川利朗,Acharya, B.,鈴木透,乃美昌司,濱田雄行,田川雅敏,田中一志,武中篤,藤澤正人,後藤章暢
- Organizer
  第46回日本癌治療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20591871
[Presentation] A new therapeutic strategy for cancer with replication-competent adenoviruses powered by the midkine promoter.
- Author(s)
  Masatoshi Tagawa, Kiyoko Kawamura, Shinya Okamoto, Yuji Tada, Koichiro Tatsumi, Kenzo Hiroshima, Hideaki Shimada.
- Organizer
  Third Midkine Symposium
- Place of Presentation
  京都市
- Year and Date
  2014-04-21 – 2014-04-23
- Data Source
  KAKENHI-PROJECT-26462000
[Presentation] Transduced p53 enhances cytotoxic effects achieved withoncolytic adenoviruses on pancreatic carcinoma cells.
- Author(s)
  江媛媛、岡本慎也、李知瀚、久保秀司、関根郁夫、滝口裕一、多田祐司、巽浩一郎、島田英昭、廣島健三、田川雅敏
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26462000
[Presentation] Immune response to tumor antigen, RalA, in patients with gastrointestinal cancers.
- Author(s)
  島田英昭、谷島聡、小池淳一、松下一之、野村文夫、日和佐隆樹、田川雅敏
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26462000
[Presentation] Activation of p53 pathways with adenoviruses bearing the p53 gene and an inhibitor for the interaction between Mdm2 and p53 produces synergistic cytotoxicity in mesothelioma.
- Author(s)
  Masatoshi Tagawa, Takaaki Kozono, Shinya Okamoto, Kengo Shimazu, Masato Shingyoji, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima.
- Organizer
  12th international conference of the international mesothelioma interested group
- Place of Presentation
  Cape Town, South Africa
- Year and Date
  2014-10-21 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-24591185
[Presentation] A small molecule that inhibits p53 degradation influences cytotoxicity of Ad-p53 in INK4A/ARF-defective mesothelioma with wild-type p53 gene.
- Author(s)
  Masatoshi Tagawa, Kiyoko Kawamura, Shinya Okamoto, Yuanyuan Jiang, Zhihan Li, Shuji Kubo, Masato Shingyoji, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
- Organizer
  17th annual meeting of American Society of Gene and Cell Therapy
- Place of Presentation
  Washington DC、USA
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591185

1. OH Keiyou (80231041)

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2. SHIMADA Hideaki (20292691)

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3. KAWAMURA Kiyoko (80260248)

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4. OCHIAI Takenori (80114255)

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5. TAKENAGA Keizo (80260256)

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6. 後藤澄雄 (10143273)

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7. MATSUBARA Hisahiro (20282486)

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8. TANIGUCHI Masaru (80110310)

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9. GUNJI Yoshio (60241957)

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10. IWADATE Yasuo (70272309)

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11. SAISHO Hiromitsu (10092058)

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13. YAMAURA Akira (40009717)

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14. MASATO Shingyoji (60450433)

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15. GOTOH Akinobu (70283885)

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16. NAMBA Hiroki (60198405)

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17. HIWASA Takaki (30260251)

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18. 小林進 (50234828)

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19. TERAO Shuji (10457103)

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20. FUJISAWA Masato (30243314)

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21. NUMASAKI Muneo (50344677)

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22. HAGIWARA Kouiti (00240705)

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23. NAGAYA Hisao (60464343)

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24. KADOTA Tomoko (00089864)

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25. MURATA Motoi (90260257)

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26. YOKOTA Naoki (00273186)

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27. NISHIZAWA Shigeru (40135257)

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28. KOSHIKAWA Nobuko (90260249)

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29. FUJISAWA Takehiko (80110328)

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30. IIZASA Toshihiko (10272303)

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31. YOSHIDA Hideo (60210712)

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32. KOUCHI Katsunori (40312938)

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33. MATSUNAGA Tadashi (80302561)

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34. SAEKI Naokatsu (30143275)

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35. MIYAZAKI Shin-ichi (40334198)

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36. URASHIMA Tetsuro (80375625)

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37. TOKUHISA Takeshi (20134364)

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38. KANNO Masamoto (40161393)

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39. TAKEMORI Toshitada (60114295)

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40. SHIGEMOTO Kazuhiro (00192104)

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41. SEKINE Ikuo (10508310)

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42. 山縣正庸 (00220244)

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43. 山崎正志 (50281712)

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44. 梶原景正 (00204397)

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46. 磯野可一 (70009489)

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47. OZAKI Toshinori (40260252)

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48. 宮内基博 (70260247)

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49. 岡住慎一 (10272311)

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50. 岩澤俊一郎 (00527913)

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51. 瀧口裕一 (30272321)

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52. TAKIGUCHI Yuuichi

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53. YAMAGUCHI Noritaka

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54. HAMADA Katsuyuki

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55. ITO Tomoko

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56. TADA Yuji

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57. KUBO Shuji

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58. SAKAIDA Emiko

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59. KATSUSHI Kurosu

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60. 名波竜規

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61. 大嶋陽幸

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62. 松下一之

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63. 山口直人

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65. 谷島聡

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66. 田辺信宏

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67. 巽浩一郎

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68. 滝口伸浩

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69. 松本邦夫

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70. 下里修

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71. 盛永敬郎

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TAGAWA MASATOSHI 田川 雅敏

TAGAWA Masatoshi 田川 雅敏

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Molecular therapy for esophageal cancer targeting the p53 and the Hippo pathwaysPrincipal InvestigatorOngoing

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A novel cancer therapeutics with gene medicine and molecular targeted agents directing the p53 pathways in esophageal carcinomaPrincipal Investigator

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Combinatory use of replication-competent adenoviruses and chemotherapeutic agents produces anti-tumor effects on human esophageal carcinoma cellsPrincipal Investigator

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Mesenchymal stem cells infected with modified adenoviruses as carrier cells that target human gastrointestinal tumorsPrincipal Investigator

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改変型細胞融解性ウイルスを搭載する間葉系幹細胞を用いた難治性消化器癌の治療Principal Investigator

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TAGAWA MASATOSHI 田川雅敏

TAGAWA Masatoshi 田川雅敏