HABUCHI Hiroko 羽渕弘子

… Alternative Names

羽渕弘子ハブチヒロコ

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Researcher Number	90329821
External Links
Affiliation (Current)	2025: 愛知医科大学, 愛知医科大学, 客員研究員
Affiliation (based on the past Project Information) *help	2016 – 2019: 愛知医科大学, 公私立大学の部局等, 客員研究員 2014: 愛知医科大学, 公私立大学の部局等, その他 2008 – 2010: Aichi Medical University, 客員研究員 2006: AICHI MEDICAL UNIVERSITY, INSTITUTION FOR MOLECULAR SCIENCE OF MEDICINE, VISITING RESEARCHER, 分子医科学研究所, 客員研究員 2001 – 2006: 愛知医科大学, 分子医科学研究所, 講師
Review Section/Research Field	Principal Investigator Structural biochemistry / Functional biochemistry / Structural biochemistry Except Principal Investigator Pain science / Biological Sciences / Functional biochemistry
Keywords	Principal Investigator 細胞増殖因子 / ヘパラン硫酸 / heparan sulfate / プロテオグリカン / growth factor / proteoglycan / heparan sulfate-O-sulfotransferases / glycosaminoglycan / 硫酸化オリゴ糖 / ノックアウトマウス … More / ヘパラン硫酸-O-硫酸転移酵素 / グリコサミノグリカン / マスト細胞 / extracellular matrix / mast cell / knockout mice / heparan sulfate 6-sulfotransferase / heparin / 肥満細胞 / ヘパラン硫酸-6-硫酸転移酵 / ヘパラン硫酸6-硫酸転移酵素 / 細胞外マトリックス / ヘパラン硫酸6_硝酸転移酵 / ヘパリン / recombinant enzymes / sulfated oligosaccharides / modified heparin / growth factors / リコンビナント酵素 / 修飾ヘパリン / isoforms / sulfated oligosaccharide / knockout mouse / 分子生物学 / 生化学 / アイソフォーム / シグナル伝達 / 酵素 / プロテアーゼ / 糖鎖生物学 / 遺伝子改変マウス / 硫酸転移酵素 / 糖鎖生物 … More Except Principal Investigator プロテオグリカン / コンドロイチン硫酸 / マクロファージ / 高硫酸化プロテオグリカン / 疼痛 / Fat pad / 膝関節炎 / P2X7、P2X4 / 骨髄由来肥満細胞 / アピラーゼ / ATP / PAR2 / トリプターゼ / 痛み / 肥満細胞 / モノヨード酢酸 / 変形性関節炎 / Mutant mouse / Glycosaminoglycans / Proteoglycans / Chondroitin sulfate / Concentration gradient / Morphogen / Cell growth factors / Heparan sulfate / 細胞外マトリックス / コンドロイチン / 形態形成因子(モルフォゲン) / 遺伝子欠損マウス / グリコサミノグリカン / 濃度勾配 / 形態形成因子 / 細胞増殖因子 / ヘパラン硫酸 / 神経細胞突起形成 / 肝星細胞 / GlaNAc4S-6ST / 骨密度 / MMP / デコリン / 肝繊維化 / GalNAc4S-6ST / デルマタン硫酸 Less

Study on the role of proteoglycans of mast cells and macrophages in the control of inflammation and pain
- Principal Investigator
  
  Habuchi Osami
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Aichi Medical University
Study on the physiological and pathological function of highly-sufated chondroitin/dermatan sulfate
- Principal Investigator
  
  HABUCHI Osami
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Aichi Medical University
Regulatory mechanisms for the activity of heparin-binding ligands through heparan sulfate proteoglycan with the specific sufation patternsPrincipal Investigator
- Principal Investigator
  
  HABUCHI Hiroko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Aichi Medical University
STUDY ON THE BIOLOBICAL AND PHYSIOLOGICAL FUNCTION OF 6-O-SULFATION IN HEPARANSULFATE/HEPARINPrincipal Investigator
- Principal Investigator
  
  HABUCHI Hiroko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  INSTITUTE FOR MOLECULAR SCIENCE OF MEDICINE, AICHI MEDICAL UNIVERSITY
STUDY ON THE INHIBITOR FOR HEPARAN SULFATE-ACTIVE DOMAINSPrincipal Investigator
- Principal Investigator
  
  HABUCHI Hiroko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  INSTITUTE FOR MOLECULAR SCIENCE OF MEDICINE, AICHI MEDCAL UNIVERSITY
Spatio-temporal regulation of morphogenesis by heparan sulfate chains
- Principal Investigator
  
  KIMATA Koji
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Aichi Medical University
STUDY ON THE BIOLOGICAL FUNCTIONS OF SPECIFIC HEPARAN SULFATE STRUCTURES GENERATED BY HEPARAN SULFATE 6-O-SULFOTRANSFERASESPrincipal Investigator
- Principal Investigator
  
  HABUCHI Hiroko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  INSTITUTE FOR MOLECULAR SCIENCE OF MEDICINE, AICHI MEDICAL UNIVERSITY

[Book] Chapter 41, Carbohydrate (Chondroitin 6) Sulfotransferase 3; Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 7 (CHST3,7) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.)2014
- Author(s)
  Habuchi O
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-23570175
[Book] Chapter 42, Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.)2014
- Author(s)
  Habuchi O
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-23570175
[Book] Chapter 44, Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.),2014
- Author(s)
  Habuchi O
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-23570175
[Book] Chapter 43, Carbohydrate (Chondroitin 4) Sulfotransferase 11-13 (CHST11-13) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.)2014
- Author(s)
  Habuchi O
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-23570175
[Book] Prog Mol Biol Transl Sci.(93)(Mice deficient in heparan sulfate 6-O-sulfotransferase-1.)2010
- Author(s)
  Habuchi H, Kimata K.
- Publisher
  Elsevier Inc.
- Data Source
  KAKENHI-PROJECT-20570113
[Book] Prog Mol Biol Tansl. Sci. Mice deficient in heparan sulfate 6-O-sulfotransferase-1.2010
- Author(s)
  Habuchi H, Kimata K
- Publisher
  Elsevier Inc
- Data Source
  KAKENHI-PROJECT-20570113
[Book] COMPREHENSIVE GLYCOSCIENCE.Chapter 3 Knockout Mice and Proteoglycans2007
- Author(s)
  Kimata, K., Habuchi, O., Habuchi, H., Watanabe,H.
- Publisher
  Elsevier(In press)
- Data Source
  KAKENHI-PROJECT-17570099
[Book] ヘパラン硫酸の微細構造に秘められた機能2007
- Author(s)
  小林孝, 羽渕弘子, 木全弘治
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Book] ヘパラン硫酸プロテオグリカンと形態形成in The Lung2007
- Author(s)
  羽渕弘子, 羽渕脩躬, 木全弘治
- Publisher
  メディカルレビュー社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Book] Knockout mice and Proteoglycans in COMPRIHENSIVE GLYCOSCIENCE.2007
- Author(s)
  Kimata K, Habuchi O, Habuchi H, Watanabe H
- Publisher
  Elsevier(In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Book] The lung ヘパラン硫酸プロテオグリカンと形態形成2007
- Author(s)
  羽渕弘子, 羽渕脩躬, 木全弘治
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17570099
[Book] Determination of substrate specificity of sulfotransferases and glycosyltransferases (proteoglycans) in Methods Enzymol.2006
- Author(s)
  Habuchi H, Habuchi O, Uchimura K, Kimata K, Muramatsu T
- Publisher
  Academic Press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Book] 第1章基礎編3.糖鎖の細胞生物グリコサミノグリカンの硫酸化と疾患.In 遺伝子医学 MOOK3 糖鎖と病気(谷口直之,editor)2006
- Author(s)
  羽渕脩躬, 羽渕弘子, 木全弘治
- Publisher
  株式会社メディドゥ
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Book] Methods Enzymol. Vol.416 chapter14, etermination of substrate specificity of sulfotransferases and glycosyltransferases(proteoglycans).2006
- Author(s)
  Habuchi, H., Habuchi, O., Uchimura, K., Kimata, K., Muramatsu,T.
- Total Pages
  19
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-17570099
[Book] 未来を拓く糖鎖科学 9.6 形態形成におけるヘパラン硫酸プロテオグリカンの機能.2005
- Author(s)
  羽渕弘子, 木全弘治
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-17570099
[Book] 遺伝子医学MOOK3 糖鎖と病気第1章糖鎖の細胞生物学 4)グリコサミノグリカンの硫酸化と疾患.2005
- Author(s)
  羽渕脩躬, 羽渕弘子, 木全弘治.
- Publisher
  メディドウ
- Data Source
  KAKENHI-PROJECT-17570099
[Book] 第1章基礎編 3.糖鎖の細胞生物学 4)グリコサミノグリカンの硫酸化と疾患.遺伝子医学MOOK3 糖鎖と病気.2005
- Author(s)
  羽渕脩躬, 羽渕弘子, 木全弘治.
- Publisher
  株式会社メディドゥ
- Data Source
  KAKENHI-PROJECT-14082206
[Book] 糖鎖機能解析 9発生・分化・形態形成9.6形態形成におけるヘパラン硫酸プロテオグリカンの機能.In未来を拓く糖鎖科学2005
- Author(s)
  羽渕弘子, 木全弘治
- Publisher
  金芳堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Book] 4.糖鎖機能解析 9 発生・分化・形態形成 9.6 形態形成におけるヘパラン硫酸プロテオグリカンの機能.未来を拓く糖鎖科学.2005
- Author(s)
  羽渕弘子, 木全弘治.
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Mice deficient in N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase exhibit enhanced liver fibrosis and delayed recovery from fibrosis in carbon tetrachloride-treated mice.2016
- Author(s)
  Habuchi H, Ushida T, Habuchi O.
- Journal Title
  
  Heliyon2
  
  Volume: 2 Issue: 8 Pages: e00138-e00138
- DOI
  10.1016/j.heliyon.2016.e00138
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08999
[Journal Article] Chondroitin sulfate-E mediates estrogen-induced osteoanabolism.2015
- Author(s)
  Koike T, Mikami T, Shida M, Habuchi O, Kitagawa H.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 8994-8994
- DOI
  10.1038/srep08994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23570175, KAKENHI-PROJECT-24590132, KAKENHI-PROJECT-25293014, KAKENHI-PLANNED-23110003
[Journal Article] Sulfated Glycosaminoglycans Control the Extracellular Trafficking and the Activity of the Metalloprotease Inhibitor TIMP-3.2014
- Author(s)
  Troeberg L, Lazenbatt C, Anower-E-Khuda MF, Freeman C, Federov O, Habuchi H, Habuchi O, Kimata K, Nagase H.
- Journal Title
  
  Chem Biol.
  
  Volume: 21 Issue: 10 Pages: 1300-1309
- DOI
  10.1016/j.chembiol.2014.07.014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23570148, KAKENHI-PROJECT-23570175
[Journal Article] Involvement of heparan sulfate 6-O-sulfation in regulation of energy metabolism and alteration of thyroid hormone levels in male mice.2013
- Author(s)
  Nagai N, Habuchi H, Sugaya N, Nakamura M, Imamura T, Watanabe H, Kimata K.
- Journal Title
  
  Glycobiology
  
  Volume: 23 Issue: 8 Pages: 980-992
- DOI
  10.1093/glycob/cwt037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590296, KAKENHI-PROJECT-23570148, KAKENHI-PROJECT-23570175, KAKENHI-PROJECT-23659556, KAKENHI-PROJECT-25293096
[Journal Article] Heparan sulfate 6-O-sulfotransferase isoform-d ependent regulatory effects of heparin on the activities of various proteases in mast cells a nd the biosynthesis of 6-O-sulfated heparin.2013
- Author(s)
  Anower-E-Khuda MF, Habuchi H, Nagai N, Habuchi O, Yokochi T, Kimata K.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288 Issue: 6 Pages: 3705-3717
- DOI
  10.1074/jbc.m112.416651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590296, KAKENHI-PROJECT-23570148, KAKENHI-PROJECT-23570175
[Journal Article] Glycosaminoglycans in blood of hereditary multiple exostoses patients: Half reduction of heparan sulfate to chondroitin sulfate ratio and the possible diagnostic application.2013
- Author(s)
  Anower-E-Khuda MF, Matsumoto K, Habuchi H, Morita H, Yokochi T, Shimizu K, Kimata K.
- Journal Title
  
  Glycobiology
  
  Volume: 23 Issue: 7 Pages: 865-876
- DOI
  10.1093/glycob/cwt024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570148, KAKENHI-PROJECT-23570175
[Journal Article] A sulfated carbohydrate epitope inhibits axon regeneration after injury2012
- Author(s)
  Brown JM, Xia J, Zhuang B, Cho KS, Rogers CJ, Gama CI, Rawat M, Tully SE, Uetani N, Mason DE, Tremblay ML, Peters EC, Habuchi O, Chen DF, Hsieh-Wilson LC
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 109 Issue: 13 Pages: 4768-4773
- DOI
  10.1073/pnas.1121318109
- Data Source
  KAKENHI-PROJECT-23570175
[Journal Article] Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin2012
- Author(s)
  Md. Ferdous Anower-E-Khuda, Hiroko Habuchi, Naoko Nagai, Osami Habuchi, Takashi Yokochi, and Koji Kimata
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Pages: 3705-3717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570175
[Journal Article] Heparan Sulfate 6-O-sulfotransferase 1 (HS6ST1), a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism2011
- Author(s)
  Tornberg J, Sykiotis G.P., Habuchi H, Pitteloud N, Bulow H.E., et al
- Journal Title
  
  Proc.Natl.Acad.Sci accepted
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Functional analysis of chick heparan sulfate 6-O-sulfotransferases in limb bud development2010
- Author(s)
  Kobayashi T, Habuchi H., et al
- Journal Title
  
  Dev Growth Differ. 52
  
  Pages: 146-156
- NAID
  10027563610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Heparan sulfate 2-O-sulfotransferase is required for triglyceride-rich lipoprotein clearance2010
- Author(s)
  Stanford KI, Habuchi H., et al
- Journal Title
  
  J Biol Chem. 285
  
  Pages: 286-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Mice deficient in N-acetylgalactosamine 4-sulfate 6-O--sulfotransferase are unable to synthesize chondroitin/dermatan sulfate containing N-acetylgalactosamine 4,6-bissulfate residues and exhibit decreased protease activity in bone marrow-derived mast cells2010
- Author(s)
  Ohtake-Niimi S, Kondo S, Ito T, Kakehi S, Ohta T, Habuchi H, Kimata K, Habuchi O.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 20793-20805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Mice deficient in N-acetylgalactosamine 4-sulfate 6-o-sulfotransferase are unable to synthesize chondroitin/dermatan sulfate containing N-acetylgalactosamine 4, 6-bissulfate residues and exhibit decreased protease activity in bone marrow-derived mast cells.--2010
- Author(s)
  Ohtake-Niimi Habuchi H, Habuchi O, et al
- Journal Title
  
  J.Biol.Chem.
  
  Volume: vol.285 Pages: 20793-20805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Preparation of chondroitin sulfate libraries containing disulfated disaccharide units and inhibition of thrombin by these chondroitin sulfates.2010
- Author(s)
  Numakura Habuchi H, Habuchi O, et al
- Journal Title
  
  Glycoconj J.
  
  Volume: vol.27 Pages: 479-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Functional analysis of chick heparan sulfate 6-O-sulfotransferases in limb bud development.2010
- Author(s)
  Kobayashi T, Habuchi H, Nogami K, Ashikari-Hada S, Tamura K, Ide H, Kimata K.
- Journal Title
  
  Dev Growth Differ. 52
  
  Pages: 146-156
- NAID
  10027563610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Preparation of chondroitin sulfate libraries containing disulfated disaccharide units and inhibition of thrombin by these chondroitin sulfates.2010
- Author(s)
  Numakura M, Kusakabe N, Ishige K, Ohtake-Niimi S, Habuchi H, Habuchi O.
- Journal Title
  
  Glycoconj J. 27
  
  Pages: 479-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Heparan sulfate 2-O-sulfotransferase is required for triglyceride-rich lipoprotein clearance.2010
- Author(s)
  Stanford KI, Wang L, Castagnola J, Habuchi H, Esko JD, et al
- Journal Title
  
  J Biol Chem. 285
  
  Pages: 286-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Specific inhibition of FGF-2 signaling with 2-O-sulfated oligosaccharides of heparan sulfate2009
- Author(s)
  Ashikari-Hada S., Habuchi H., et al
- Journal Title
  
  Glycobiology (in press)
  
  Pages: 11-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Specific inhibition of FGF-2 signaling with 2-O-sulfated octasaccharides of heparan sulfate2009
- Author(s)
  Ashikari-Hada S, Habuchi H, Sugaya N, Kobayashi T, Kimata K.
- Journal Title
  
  Glycobiology 19
  
  Pages: 644-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Specific inhibition of FGF-2 signaling with 2-O-sulfated octasaccharides of heparan sulfate2009
- Author(s)
  Ashikari-Hada S, Habuchi H., et al
- Journal Title
  
  Glycobiology 19
  
  Pages: 644-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] 6-O-sulfation of heparan sulfate differentially regulates various fibroblast growth factor-dependent signalings in culture.2008
- Author(s)
  Sugaya N, Habuchi H, Nagai N, Ashikari-Hada S, Kimata K.
- Journal Title
  
  J Biol Chem. 283
  
  Pages: 10366-10376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] 6-O-sulfation of Heparan Sulfate Differentially Regulates various Fibroblast Growth Factor-depend2008
- Author(s)
  Sugaya N., Habuchi H., Kimata K., et al
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 10366-10376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] ヘパラン硫酸プロテオグリカンの器官形成と疾患における役割2008
- Author(s)
  羽渕弘子木全弘治
- Journal Title
  
  生体の科学 59
  
  Pages: 83-91
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] ヘパラン硫酸プロテオグリカンの器官形成と疾患における役割2008
- Author(s)
  羽渕弘子、木全弘治
- Journal Title
  
  生体の科学 59
  
  Pages: 83-91
- Data Source
  KAKENHI-PROJECT-20570113
[Journal Article] Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation and late embryonic lethality.2007
- Author(s)
  Habuchi H, Nagai N, Sugaya N, Atsumi F, Stevens RL, Kimata K.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 15578-15588
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation and late embryonic lethality.2007
- Author(s)
  Habuchi H
- Journal Title
  
  J. Biol. Chem. 282巻・21号
  
  Pages: 15578-15588
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Mice deficient in heparan sukfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation and late embryonic lethelity2007
- Author(s)
  Habuchi, H., Nagai, N., Sugaya, N., Atsumi, F., Stevens, RL, Kimata, K
- Journal Title
  
  J. Biol. Chem 282
  
  Pages: 15578-15588
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Essential role of heparan sulfate 2-O-sulfotransferase in chick limb bud patterning and development.2007
- Author(s)
  Kobayashi T, Habuchi H, Tamura K, Ide H, Kimata K
- Journal Title
  
  J Biol Chem 282
  
  Pages: 19589-19597
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Knockout Mice and Proteoglycans. Comprehensive Glycoscience, - From Chemistry to Systems Biology (Ed.-in-Chief, J P Kamerling ; Subject Ed., A.Suzuki)2007
- Author(s)
  Kimata K, Habuchi O, Habuchi H, Watanabe H
- Journal Title
  
  Elsevier Vol 4
  
  Pages: 33-33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Essential role of heparan sulfate 2-O-sulfotransferase in chick limb bud patterning and development.2007
- Author(s)
  Kobayashi T, Habuchi H, Tamura K, Ide H, Kimata K.
- Journal Title
  
  J.Biol.Chem. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Regulation of heparan sulfate 6-O-sulfation by beta-secretase activity2007
- Author(s)
  Nagai, N., Habuchi, H., Kitazume, S., Toyoda, H., Hashimoto, Y., Kimata, K.
- Journal Title
  
  J. Biol. Chem 282
  
  Pages: 14942-14951
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Characterization of Anti-heparan sulfate phage-display antibodies AO4B08 and HS4E42007
- Author(s)
  Kurup S, Wijnhoven T.J.M., Jenniskens G.J., Kimata K., Habuchi H., Li J-P., Lindahl U., van Kuppervelt T.H., Spillmann D.
- Journal Title
  
  J.Biol.Chem. (in pres)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Regulation of heparan sulfate 6-0-sulfation by beta-secretase activity2007
- Author(s)
  Nagai, N., Habuchi, H., Kitazume, S., Toyoda, H., Hashimoto, Y., Kimata, K.
- Journal Title
  
  J.Biol.Chem. (In press)
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Regulation of heparan sulfate 6-O-sulfation by beta-secretase activity.2007
- Author(s)
  Nagai N, Habuchi H, Kitazume S, Toyoda H, Hashimoto Y, Kimata K.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 14942-14951
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Mice deficient in heparan sukfate 6-0-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation and late embryonic lethelity2007
- Author(s)
  Habuchi, H., Nagai, N., Sugaya, N., Atsumi, F., Stevens, RL, Kimata,K
- Journal Title
  
  J. Biol. Chem. (In press)
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Characterization of Anti-heparan sulfate phage-display antibodies AO4B08 and HS4E42007
- Author(s)
  Kurup S, Wijnhoven T.J.M., Jenniskens G.J., Kimata K., Habuchi H., Li J-P., Lindahl U., van Kuppervelt T.H., Spillmann D
- Journal Title
  
  J. Biol. Chem (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Essential role of heparan sulfate 2-O-sulfotransferase in chick limb bud patterning and development.2007
- Author(s)
  Kobayashi T, Habuchi H, Tamura, K, Ide H, Kimata K
- Journal Title
  
  J. Biol. Chem (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Versican/PG-M Regulates Chondrogenesis as an Extracellular Matrix Molecule Crucial for Mesenchymal Condensation.2006
- Author(s)
  Kamiya N, Habuchi H, Kimata K et al.
- Journal Title
  
  J.Biol.Chem. 281
  
  Pages: 2390-2400
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Specific and flexible roles of heparan sulfate modifications in Drosophila FGG signaling.2006
- Author(s)
  Kamimura K, Koyama T, Habuchi H, Ueda R, Masu M, Kimata K, Nakato H.
- Journal Title
  
  J.Cell Biol. 174
  
  Pages: 773-778
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Versican/PG-M regulates chondrogenesis as an extracellular matrix molecule crucial for mesenchymal condensation.2006
- Author(s)
  Kamiya N, Watanabe H, Habuchi H, Takagi H, Shinomura T, Shimizu K, Kimata K
- Journal Title
  
  . J Biol Chem. 281
  
  Pages: 2390-2400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Versican/PG-M regulates chondrogenesis as an extracellular matrix molecule crucial for mesenchymal condensation2006
- Author(s)
  Kamiya, N., Watanabe, H., Habuchi, H., Takagi, H., Shinomura, T., Shimizu, K., Kimata,K.
- Journal Title
  
  J.Biol.Chem. 281
  
  Pages: 2390-2400
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Versican/PG-M regulates chondrogenesis as an extracellular matrix molecule crucial for mesenchymal condensation.2006
- Author(s)
  Kamiya N, Watanabe H, Habuchi H, Takagi H, Shinomura T, Shimizu K, Kimata K.
- Journal Title
  
  J.Biol.Chem. 281
  
  Pages: 2390-2400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Specific and flexible roles of heparan sulfate modification in Drosophila FGF signaling2006
- Author(s)
  Kamimura, K., Koyama, T., Habuchi, H., Ueda, R., Masu, M., Kimata, K., Nakato,H.
- Journal Title
  
  J.Cell Biol. 174
  
  Pages: 773-778
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling.2006
- Author(s)
  Kamimura K, Koyama T, Habuchi H, Ueda R, Masu M, Kimata K, Nakato H
- Journal Title
  
  J Cell Biol 174
  
  Pages: 773-778
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Versican/PG-M regulates chondrogenesis as an extracellular matrix molecule crucial for mesenchymal condensation2006
- Author(s)
  Kamiya, N., Watanabe, H., Habuchi.H., Takagi, H., Shinomura, T., Shimizu, K., Kimata, K.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 2390-2400
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Heparin regulates vascular endothelial growth factor165-dependent mitogenic activity, tube formation, and its receptor phosphorylation of human endothelial cells. Comparison of the effects of heparin and modified heparins.2005
- Author(s)
  S.Ashikari-Hada, H.Habuchi, et al.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 31508-31515
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Heparin regulates vascular endothelial growth factor165 -dependent mitogenic activity, tube formation, and its receptor phosphorylation of human endothelial cells2005
- Author(s)
  Ashikari-Hada S, Habuchi H, Kariya Y, Kimata K
- Journal Title
  
  J. Biol. Chem 280
  
  Pages: 31508-31515
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Heparin regulates vascular endothelial growth factor 165-dependent mitogenic activity, tube formation, and its receptor phosphorylation of human endothelial cells.2005
- Author(s)
  Ashikari-Hada S, Habuchi H, Kariya Y, Kimata K.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 31508-3151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Heparin regulates vascular endothelial growth factor165-dependent mitogenic activity, tube formation, and its receptor phosphorylation of human endothelial cells.2005
- Author(s)
  Ashikari-Hade S, Habuchi H, Kimata K
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 31508-31515
- Data Source
  KAKENHI-PROJECT-17570099
[Journal Article] Heparin regulates vascular endothelial growth factorl65-dependent mitogenic activity, tube formation, and its receptor phosphorylation of human endothelial cells. Comparison of the effects of heparin and modified heparins.2005
- Author(s)
  Ashikari-Hada S, Habuchi H, Kariya Y, Kimata K
- Journal Title
  
  J Biol Chem 174
  
  Pages: 31508-31515
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] In vivo hyaluronan synthesis bu expression of mammalian hyaluronan synthase gene in drosophila.2004
- Author(s)
  Takeo S, Fujise M, Akiyama T, Habuchi H, Nakato H, et al.
- Journal Title
  
  J Biol Chem 279, 18
  
  Pages: 18920-18925
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Sulfation pattern in glycosaminoglycan : does it have a code?2004
- Author(s)
  Habuchi H, Habuchi O, Kimata K
- Journal Title
  
  Glycoconj J. 21, 1-2
  
  Pages: 47-52
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Stem domains of heparan sulfate 6-O-sulfotransferase are required for Golgi localization, oligomer formation and enzyme activity.2004
- Author(s)
  Nagai N, Habuchi H.Esko JD, Kimata K.
- Journal Title
  
  J Cell Sci. 117
  
  Pages: 3331-3341
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Sulfation pattern in glycosaminoglycan : does it have a code?2004
- Author(s)
  Habuchi H, Habuchi O, Kimata K
- Journal Title
  
  Glycoconj J. 21,1-2
  
  Pages: 47-52
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Distinctive expression patterns of heparan sulfate O-sulfotransferases and regional differences in heparan sulfate structure in chick limb buds2004
- Author(s)
  Nogami K, Suzuki H, Habuchi H, Ishiguro N, Iwata H, Kimata K.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 8219-8229
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Characterization of growth factor-binding structures in heparin/heparan sulfte using an octasaccharide library.2004
- Author(s)
  S.Ashikari-Hada, H.Habuchi, et al.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 12346-12354
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Characterization of growth factor-binding structures in heparin/heparan sulfate using an octasaccharide library.2004
- Author(s)
  Ashikari-Hada S, Habuchi H, Kariya Y, Itoh N, Reddi AH, Kimata K.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 12346-12354
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Stem domains of heparan sulfate 6-O-sulfotransferase are required for Golgi localization, oligomer formation and enzyme activity.2004
- Author(s)
  Nagai N, Habuchi H, Esko JD, Kimata K.
- Journal Title
  
  J.Cell Sci. 117
  
  Pages: 3331-3341
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] In vivo hyaluronan synthesis upon expression of the mammalian hyaluronan synthase gene in Drosophila.2004
- Author(s)
  Takeo S, Fujise M, Akiyama T, Habuchi H, Itano N, Matsuo T, Aigaki T, Kimata K, Nakato H.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 18920-18925
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Distinctive expression patterns of heparan sulfate O-sulfotransferases and regional differences in heparan sulfate structure in chick limb buds.2004
- Author(s)
  Nogami K, Suzuki H, Habuchi H, Ishiguro N, Iwata H, Kimata K.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 8219-8229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Distinctive expression patterns of heparan sulfate O-sulfotransferases and regional differences in heparan sulfate.2004
- Author(s)
  Nogami k, Habuchi H, Kimata K I et al.
- Journal Title
  
  J Biol Chem 279, 9
  
  Pages: 8219-8229
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Stem domains of heparan sulfate 6-O-sulfotransferase are required for Golgi localization oligomer formation and enzyme activity2004
- Author(s)
  Nagai N, Habuchi H, Esko JD, Kimata K.
- Journal Title
  
  J Cell Sci. 117
  
  Pages: 3331-3341
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Sulfation pattern in glycosaminoglycan : Does it have a code?2004
- Author(s)
  H.Habuchi, O.Habuchi, et al.
- Journal Title
  
  Glycoconj J 21
  
  Pages: 47-52
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Sulfation pattern in glycosaminoglycan : does it have a code?2004
- Author(s)
  Habuchi H, Habuchi O, Kimata K.
- Journal Title
  
  Glycoconj.J. 21
  
  Pages: 47-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] In vivo hyaluronan synthesis upon expression of the mammalian hyaluronan synthase gene in Drosophila.2004
- Author(s)
  Takeo S, Fujise M, Akiyama T, Habuchi H, Itano N, Kimata K, Nakato H.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 18920-18925
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Stem domains of heparan sulfate 6-O-sulfotransferase are required for Golgi localization, oligomer formation and enzyme activity.2004
- Author(s)
  N.Nagai, H.Habuchi, et al.
- Journal Title
  
  J Cell Sci 117
  
  Pages: 3331-3341
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Characterization of growth factor-binding structures in heparin/heparan sulfate using an octasaccharide library.2004
- Author(s)
  Ashikari-Hada S, Habuchi H.Kimata K.et al.
- Journal Title
  
  J Biol Chem 279, 13
  
  Pages: 12346-12354
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Characterization of growth factor-binding structures in heparin/heparan sulfate using an octasaccharide library2004
- Author(s)
  Ashikari-Hada S, Habuchi H, Kariya Y, Itoh N, Reddi AH, Kimata K
- Journal Title
  
  J Biol Chem 279
  
  Pages: 12346-12354
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Heparan sulfate 6-O-sulfotransferase is essential for muscle development in zebrafish.2003
- Author(s)
  Bink RJ, Habuchi H, Lele Z, Dolk E, Joore J, Rauch GJ, Geisler R, Kimata K, Zivkovic D.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 31118-31127
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Biosynthesis of heparan sulphate with diverse structures And functions : two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties2003
- Author(s)
  Habuchi H, Miyake G, Nogami K, Kuroiwa A, Matsuda Y Kusche-Gullberg M, Habuchi O, Tanaka M, Kimata K.
- Journal Title
  
  Biochem.J. 371
  
  Pages: 31-42
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Substrate specificities of mouse heparan sulphate glucosaminyl 6-O-suiphotransferases.2003
- Author(s)
  Smeds E, Habuchi H, Do AT, Hjertson E, Grundberg H, Kimata K, Lindahi U, Kusche-Gullberg M.
- Journal Title
  
  Biochem.J. 372
  
  Pages: 24371-24376
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Molecular diversity and biological functions of proteoglycan sulfotransferase2003
- Author(s)
  Habuchi O, Habuchi H, Kimata K.
- Journal Title
  
  蛋白・核酸・酵素 48
  
  Pages: 1010-1018
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Oligosaccharide library-based assessment of heparan sulfate 6-O-sulfotransferase substrate specificity.2003
- Author(s)
  Jemth P, Smeds E, Do AT, Habuchi H, Kimata K, Lindahl U, Kusche-Gullberg M.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 24371-24376
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Substrate specificities of mouse heparan sulphate glucosaminyl 6-O-sulphotransferases2003
- Author(s)
  Smeds E, Habuchi H, Do AT, Hjertson E, Grundberg H, Kimata K, Lindahl U
- Journal Title
  
  Biochem.J 372
  
  Pages: 371-380
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Heparan sulfate 6-o-sulfotransferase is essential for muscle development in zebrafish.2003
- Author(s)
  Bink RJ, Habuchi H, Lele Z, Dolk E, Joore J, Rauch QJ, Geisler R, Wilson SW, den Hertog J, Kimata K, Zivkovic D
- Journal Title
  
  J Biol Chem 278
  
  Pages: 31118-31127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Oligosaccharide library-based assessment of heparan Sulfate 6-O-sulfotransferase substrate specificity.2003
- Author(s)
  Jemth P, Smeds E, Do AT, Habuchi H, Kimata K, Lindahl U, Kusche-Gullberg M.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 24371-24376
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Heparan sulfate 6-O-sulfotransferase is essential for muscle development in zebrafish.2003
- Author(s)
  Bink RJ, Habuchi H, Lele Z, Dolk E, Joore J, Rauch GJ, Geisler R, Wilson SW, den, Hertog J, Kimata K, Zivkovic D.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 31118-31127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Biosynthesis of heparan sulphate with diverse structures and functions : two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression2003
- Author(s)
  Habuchi H, Miyake G, Nogami K, Kusche-Gullberg M, Habuchi O, Tanaka M, Kimata
- Journal Title
  
  Biochem.J 371
  
  Pages: 31-42
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Heparan sulfate is required for bone morphogenetic protein-7signaling.2003
- Author(s)
  Irie A, Habuchi H, Kimata K, Sanai Y.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 308
  
  Pages: 858-865
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Journal Article] Heparan sulfate is required for bone morphogenetic protein-7 signaling.2003
- Author(s)
  Irie A, Habuchi H, Kimata K, Sanai Y.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 308
  
  Pages: 858-865
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Patent] クラミジア感染症処置剤2010
- Inventor(s)
  藪下廣光、羽渕弘子、木全弘治
- Industrial Property Rights Holder
  生化学工業株式会社
- Acquisition Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-20570113
[Patent] ノックアウト動物2009
- Inventor(s)
  木全弘治、羽渕弘子、佐藤尚子
- Industrial Property Rights Holder
  生化学工業株式会社
- Industrial Property Number
  2009-193909
- Filing Date
  2009-08-25
- Data Source
  KAKENHI-PROJECT-20570113
[Patent] 硫酸基転移酵素及びそれをコードするDNA2008
- Inventor(s)
  羽渕弘子、田中雅之、木全弘治
- Industrial Property Rights Holder
  生化学工業株式会社
- Acquisition Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-20570113
[Patent] ヘパラン硫酸6-O-硫酸基転移酵素2006
- Inventor(s)
  羽渕弘子, 羽渕脩躬
- Industrial Property Rights Holder
  生化学工業
- Acquisition Date
  2006-06-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Patent] ノックアウト動物2005
- Inventor(s)
  木全弘治, 羽渕弘子
- Industrial Property Rights Holder
  生化学工業
- Industrial Property Number
  2005-058162
- Filing Date
  2005-03-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Patent] ヘパラン硫酸 2-O-硫酸基転移酵素2005
- Inventor(s)
  小林政, 羽渕弘子, 羽
- Industrial Property Rights Holder
  生化学工業
- Acquisition Date
  2005-04-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Patent] 硫酸基転移酵素阻害剤2004
- Inventor(s)
  木全弘治, 羽渕弘子
- Industrial Property Rights Holder
  生化学工業
- Industrial Property Number
  2005-506231
- Filing Date
  2004-11-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Patent] ノックアウト動物2003
- Inventor(s)
  木全弘治, 羽渕弘子, 佐藤尚子
- Industrial Property Rights Holder
  生化学工業株式会社
- Filing Date
  2003-08-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Patent] 硫酸転移酵素阻害剤2003
- Inventor(s)
  羽渕弘子, 木全弘治
- Industrial Property Rights Holder
  生化学工業株式会社
- Filing Date
  2003-05-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570126
[Presentation] MIA誘起OAマウスへの骨髄由来マスト細胞(BMMC)移入による疼痛発症にはトリプターゼの受容体であるPAR2活性化が関与する2019
- Author(s)
  羽渕弘子、泉仁、團隼兵、牛田享宏、池内昌彦、羽渕脩躬
- Organizer
  第41回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-16K08999
[Presentation] MIA誘起OAマウスへの骨髄由来マスト細胞（BMMC）移入による疼痛発症にはトリプターゼの受容体であるPAR2活性化が関与する2019
- Author(s)
  羽渕弘子、泉仁、團隼兵、牛田享宏、池内昌彦、羽渕脩躬
- Organizer
  第41回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-16K08999
[Presentation] 変形性関節症モデルマウスにおけるマスト細胞の疼痛誘起作用2018
- Author(s)
  羽渕弘子、泉仁、團隼兵、牛田享宏、池内昌彦、羽渕脩躬
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08999
[Presentation] 変形性関節症モデルにおけるマスト細胞の役割2016
- Author(s)
  泉仁、羽渕弘子、羽渕脩躬、池内昌彦、牛田享宏
- Organizer
  第9回運動器疼痛学会
- Place of Presentation
  御茶ノ水ソラシティカンファレンスセンター
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16K08999
[Presentation] 高硫酸化デルマタン硫酸は肝繊維化の回復に寄与2013
- Author(s)
  羽渕弘子、羽渕脩躬
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23570175
[Presentation] Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin.2012
- Author(s)
  Md.Ferdous Anower-E-Khuda, Hiroko Habuchi, Naoko Nagai, Takashi Yokochi, Osami Habuchi, Noriko Sugaya, Koji Kimata
- Organizer
  Gordon Research Conference (Proteoglycans )
- Place of Presentation
  Proctor Academy, Andover, NH, USA
- Data Source
  KAKENHI-PROJECT-23570175
[Presentation] 6-O-sulfation of heparin is essential for storage and activities of proteases in connective tissue mast cells2011
- Author(s)
  Md Ferdous Anower-E-Kuda, Hiroko Habuchi, Naoko Nagai, Takashi Yokochi, Osami Habuchi, Noriko Sugaya, Koji Kimata
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23570175
[Presentation] 二糖二硫酸単位を含むコンドロイチン硫酸ライブラリーの調製とこれらのコンドロイチン硫酸によるトロンビン活性の阻害2010
- Author(s)
  沼倉真理緒、日下部教子、石毛和也、大竹-新美しおり、羽渕弘子、羽渕脩躬
- Organizer
  BMB2010(第83会日本生化学会大会)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20570113
[Presentation] preparation of chondroitin sulfate libraries containing disulfated disaccharide.---2010
- Author(s)
  沼倉、日下部石毛、大竹、羽渕、羽渕
- Organizer
  BMB2010(第83回日本生化学会大会)
- Place of Presentation
  神戸ポートアイランド((兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20570113
[Presentation] 培養マスト細胞におけるヘパリンの2-硫酸化と2-硫酸化ヘパリンの機能2009
- Author(s)
  羽渕弘子, 羽渕脩躬, 木全弘治, ら
- Organizer
  日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20570113
[Presentation] 培養マスト細胞におけるヘパリンの2-硫酸化と2-硫酸化ヘパリンの機能2009
- Author(s)
  羽渕弘子、羽渕脩躬、木全弘治
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20570113

1. HABUCHI Osami (90024067)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
2. KIMATA Koji (10022641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
3. NAGAI Naoko (00367799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

HABUCHI Hiroko 羽渕 弘子

羽渕 弘子 ハブチ ヒロコ

Research Projects

Research Products

Co-Researchers

Study on the role of proteoglycans of mast cells and macrophages in the control of inflammation and pain

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Study on the physiological and pathological function of highly-sufated chondroitin/dermatan sulfate

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Regulatory mechanisms for the activity of heparin-binding ligands through heparan sulfate proteoglycan with the specific sufation patternsPrincipal Investigator

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STUDY ON THE BIOLOBICAL AND PHYSIOLOGICAL FUNCTION OF 6-O-SULFATION IN HEPARANSULFATE/HEPARINPrincipal Investigator

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STUDY ON THE INHIBITOR FOR HEPARAN SULFATE-ACTIVE DOMAINSPrincipal Investigator

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Spatio-temporal regulation of morphogenesis by heparan sulfate chains

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STUDY ON THE BIOLOGICAL FUNCTIONS OF SPECIFIC HEPARAN SULFATE STRUCTURES GENERATED BY HEPARAN SULFATE 6-O-SULFOTRANSFERASESPrincipal Investigator

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[Book] Chapter 41, Carbohydrate (Chondroitin 6) Sulfotransferase 3; Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 7 (CHST3,7) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.)2014

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[Book] Chapter 42, Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.)2014

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[Book] Chapter 44, Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.),2014

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[Book] Chapter 43, Carbohydrate (Chondroitin 4) Sulfotransferase 11-13 (CHST11-13) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.)2014

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[Book] Prog Mol Biol Transl Sci.(93)(Mice deficient in heparan sulfate 6-O-sulfotransferase-1.)2010

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[Book] Prog Mol Biol Tansl. Sci. Mice deficient in heparan sulfate 6-O-sulfotransferase-1.2010

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[Book] COMPREHENSIVE GLYCOSCIENCE.Chapter 3 Knockout Mice and Proteoglycans2007

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[Book] ヘパラン硫酸の微細構造に秘められた機能2007

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HABUCHI Hiroko 羽渕弘子

羽渕弘子ハブチヒロコ

[Book] 第1章基礎編3.糖鎖の細胞生物グリコサミノグリカンの硫酸化と疾患.In 遺伝子医学 MOOK3 糖鎖と病気(谷口直之,editor)2006

[Book] 遺伝子医学MOOK3 糖鎖と病気第1章糖鎖の細胞生物学 4)グリコサミノグリカンの硫酸化と疾患.2005

[Book] 第1章基礎編 3.糖鎖の細胞生物学 4)グリコサミノグリカンの硫酸化と疾患.遺伝子医学MOOK3 糖鎖と病気.2005