Kose Shingo 小瀬真吾

… Alternative Names

KOSE Shingo 小瀬真吾

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Researcher Number	90333278
Other IDs
External Links
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 開拓研究所, 専任研究員
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人理化学研究所, 開拓研究所, 専任研究員 2018 – 2023: 国立研究開発法人理化学研究所, 開拓研究本部, 専任研究員 2015 – 2016: 国立研究開発法人理化学研究所, 今本細胞核機能研究室, 専任研究員 2007 – 2014: RIKEN, 今本細胞核機能研究室, Senior Staff Scientist 2007: The Institute of Physical and Chemical Research, 今本細胞核機能研究室, 専任研究員 … More 2004 – 2006: RIKEN, Cellular Dynamics Laboratory, Research Scientist, 今本細胞核機能研究室, 研究員 2002 – 2003: RIKEN, Cellular Dynamics Laboratory, Research Scientist, 細胞核機能研究室, 研究員 2002: 理化学研究所, 細胞核機能研究室, 研究員 2001 – 2002: 国立遺伝学研究所, 構造遺伝学研究センター, 助手 2001: 国立遺伝学研究所, 構造遺伝研究センター, 助手 Less
Review Section/Research Field	Principal Investigator Cell biology / Biological Sciences / Basic Section 44010:Cell biology-related / Basic Section 43010:Molecular biology-related / Cell biology Except Principal Investigator Cell biology / Basic Section 44010:Cell biology-related / Cell biology / Gastroenterology / Biological Sciences
Keywords	Principal Investigator 分子シャペロン / importin / 核内移行 / 核-細胞質間輸送 / 熱ショック / 核-細胞質間分子輸送 / 熱ショック蛋白質 / 核外移行 / 核膜孔 / ストレス応答 … More / Hikeshi / 熱ショックストレス / 熱ストレス / Importin / 分化 / 核ー細胞質間輸送 / タンパク質恒常性維持 / ストレス顆粒 / HSF1 / HSP70 / 転写制御 / 熱ストレス応答 / Hsp70 / ストレス / 熱ショック応答 / 核内輸送 / Importin β / 核-細胞質間たんぱく質輸送 / 核-細胞質問輸送 / 核-細胞質間蛋白質輸送 / β-カテニン / 核膜孔複合体 / 核蛋白質輸送担体 … More Except Principal Investigator 核膜孔複合体 / 低分子量GTPase Ran / importin β / 核-細胞質間輸送 / セミインタクト細胞 / 核ー細胞質間輸送 / タンパク質毒性ストレス / HSF1 / Hikeshi / 分子シャペロンHsp70 / 熱ストレス / nuclear transport / 輸送担体 / β-catenin / CAS / importinβ / 核膜 / 転写因子HSF1 / 熱ショックタンパク質 / プロテオスタシス / 分子シャペロンHsp70　HSF1 / タンパク質の恒常性 / ノックアウトマウス / グルコース飢餓 / 蛍光相互相関法 / 神経遺伝性疾患 / 熱ショックストレス / タンパク質恒常性 / 核－細胞質間輸送 / Mitotic chromosome / Importin / Nucleocvtoplasmic transport / Live imaging / Cell Cycle / Small GTPase Ran / Nuclear Envelope / Nuclear Pore Complex / Lap2α / LBR(Lamin B receptor) / emerin / B-type lamin / A-type lamin / 核内膜 / インシュレーター / CDKインヒビター / 細胞核 / マルチ遺伝子発現システム / Photobleach / 染色体 / インポーチン / 核内膜タンパク質 / 生細胞イメージング / 細胞周期 / 70kDa heat-shock cognate protein / semi-intact cells / nuclear pore comlex / single molecule imaging / 核膜孔複合体構成因子 / 核局在化シグナル / β-カテニン / Importinβ / 分子シャペロンhsc70 / 1分子イメージング / 70kDa heat-shock cognate protein (hsc70) / nuclear pore complex / importin α / small GTPase Ran / リサイクリング / hsc70 / NTF2 / p10 / 核外輸送担体CAS / 核内輸送担体importinβ / 70kDa熱ショックタンパク質(hsc70) / 核膜孔複合体(nuclcar pore complex) / importinα / 核一細胞質間輸送 / 質量分析法 / 安定同位体標識 / 輸送再構成系 / インポーティン / 脂肪性肝炎 / アルコール性肝炎 / 非アルコール肝炎(NASH) / マウスアルコール肝炎(ASH) / 線維化 / アポトーシス / c-Met / Sp1 / 非アルコール脂肪性肝炎 / 小胞体ストレス / 架橋反応 / トランスグルタミナーゼ / アルコール脂肪性肝炎 / Sp1, c-Met,アポトーシス / 核-細胞質間輸送因子 / 分裂期染色体 / 細胞分裂期 / 核膜前駆体小胞 / LBR / Emerin / 細胞分裂 / リアルタイムイ蛍光メージング / 紡錘体 / 膜貫通型核膜因子 / 核ラミナ Less

Hikeshiが制御する分子シャペロンHSP70核内輸送の活性化機構Principal Investigator
- Principal Investigator
  
  小瀬真吾
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Institute of Physical and Chemical Research
Nuclear function and stress response of HSP70 regulated by nucleocytoplasmic transport carrier HikeshiPrincipal Investigator
- Principal Investigator
  
  Kose Shingo
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Institute of Physical and Chemical Research
Analysis of function of Hikeshi affecting cellular homeostasis
- Principal Investigator
  
  Imamoto Naoko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Institute of Physical and Chemical Research
Analysis of molecular mechanism and physiological functions of the stress-responsive nucleocytoplasmic transport mediated by HikeshiPrincipal Investigator
- Principal Investigator
  
  Kose Shingo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Institute of Physical and Chemical Research
Analysis of Function and Mechanism of nuclear transport carrier Hikeshi
- Principal Investigator
  
  Imamoto Naoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Institute of Physical and Chemical Research
Mechanism and function of a novel stress-induced nuclear import pathwayPrincipal Investigator
- Principal Investigator
  
  KOSE Shingo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  The Institute of Physical and Chemical Research
核ー細胞質間輸送システムの統合的解析に向けた基盤作り
- Principal Investigator
  
  今本尚子
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  The Institute of Physical and Chemical Research
Importin βファミリー分子が創りだす細胞内分子流通システムとその機能解析Principal Investigator
- Principal Investigator
  
  小瀬真吾
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Studies on a role of a crosslinking enzyme, transglutaminase in pathogenesis of liver diseases
- Principal Investigator
  
  KOJIMA Soichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The Institute of Physical and Chemical Research
Identification and analysis of nucleocytoplasmic transport pathway using our novel assay systemPrincipal Investigator
- Principal Investigator
  
  KOSE Shingo
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  The Institute of Physical and Chemical Research
核膜サブドメインを形成する分子基盤と形成機構の解析
- Principal Investigator
  
  今本尚子
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
細胞の増殖と停止・分化における核ー細胞質間タンパク質輸送機構の役割Principal Investigator
- Principal Investigator
  
  小瀬真吾
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  The Institute of Physical and Chemical Research
Role of Nuclear Pore Complexes on Nuclear Organization
- Principal Investigator
  
  IMAMAOTO Naoko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  The Institute of Physical and Chemical Research
核-細胞質間蛋白質輸送の制御:輸送経路のインタープレイと刺激応答に伴う変化Principal Investigator
- Principal Investigator
  
  小瀬真吾
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Importin β核蛋白質輸送担体分子の核膜孔通過における制御機構の解析Principal Investigator
- Principal Investigator
  
  小瀬真吾
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Analysis of nuclear pore translocation mechanism : single molecule analysis and biochemical approach
- Principal Investigator
  
  IMAMOTO Naoko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  RIKEN
核-細胞質間蛋白質輸送の制御機構における熱ショック蛋白質hsc70の機能解析Principal Investigator
- Principal Investigator
  
  小瀬真吾
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
輸送担体importin βの核膜孔通過における熱ショック蛋白質hsc70の機能Principal Investigator
- Principal Investigator
  
  小瀬真吾
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  National Institute of Genetics
Analysis of transport mechanism and regulation through the recycling of transport factors.
- Principal Investigator
  
  IMAMOTO Naoko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  RIKEN
  National Institute of Genetics

[Book] Thermal Stress and Nuclear Transport. “Thermal Biology”2022
- Author(s)
  Shingo Kose, Yutaka Ogawa, Naoko Imamoto.
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-18H02442
[Book] Methods Mol. Biol.2015
- Author(s)
  Kose, S., Funakoshi, T., Imamoto, N
- Total Pages
  12
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-26251021
[Book] Reconstitution of nucleocytoplasmic transport using digitonin-permeabilized cells.2015
- Author(s)
  Kose S, Funakoshi T, *Imamoto N.
- Publisher
  Methods Mol. Biol1262:
- Data Source
  KAKENHI-PROJECT-26251021
[Book] 生化学2015
- Author(s)
  小瀬真吾
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PROJECT-26440109
[Book] Analysis of nucleocytoplasmic transport in digitonin-per meabilized cells under different cellular conditions.2014
- Author(s)
  Furuta M, Kose S, Kehlenbach RH, *Imamoto N.
- Publisher
  Methods Cell Biol.22:
- Data Source
  KAKENHI-PROJECT-26251021
[Book] 実験医学2012
- Author(s)
  小瀬真吾、今本尚子
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23570242
[Book] 細胞質から核へのタンパク質輸送2008
- Author(s)
  小瀬真吾、今本尚子
- Publisher
  (株)シーエムシー出版
- Data Source
  KAKENHI-PROJECT-20770166
[Book] 化合物で乗り物タンパク質を発見2008
- Author(s)
  小瀬真吾
- Publisher
  (株)オーム社
- Data Source
  KAKENHI-PROJECT-20770166
[Book] 機能性 DDS キャリアの製剤設計2008
- Author(s)
  小瀬真吾, 他
- Total Pages
  6
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-19038027
[Journal Article] Lack of Hikeshi activates HSF1 activity under normal conditions and disturbs the heat shock response2022
- Author(s)
  Shingo Kose、Kenichiro Imai、 Ai Watanabe、Akira Nakai、Yutaka Suzuki、Naoko Imamoto
- Journal Title
  
  Life Science Alliance
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02442
[Journal Article] Lack of Hikeshi activates HSF1 activity under normal conditions and disturbs the heat-shock response.2022
- Author(s)
  Kose, S., Imai, K., Watanabe, A., Nakai, A., Suzuki, Y., Imamoto, N.
- Journal Title
  
  Life Sci. Alliance
  
  Volume: 5 Issue: 9 Pages: e202101241-e202101241
- DOI
  10.26508/lsa.202101241
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06500, KAKENHI-PROJECT-21H02697, KAKENHI-PROJECT-21H02482
[Journal Article] Extensive cargo identification reveals distinct biological roles of the 12 Importin2017
- Author(s)
  Kimura, M., Morinaka, Y., Imai, K., Kose, S, Horton, P, Imamoto, N
- Journal Title
  
  eLife
  
  Volume: 2017 Pages: 21184-21184
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26251021
[Journal Article] Extensive cargo identification reveals distinct biological roles of the 12 Importin pathways2017
- Author(s)
  Kimura, M., Morinaka, Y., Imai, K., Kose, S, Horton, P, Imamoto, N
- Journal Title
  
  eLife
  
  Volume: 6
- DOI
  10.7554/elife.21184
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-15H05929, KAKENHI-PROJECT-26440109, KAKENHI-PROJECT-15K07064
[Journal Article] Leukoencephalopathy and early death associated with an Ashkenazi-Jewish founder mutation in the Hikeshi gene2016
- Author(s)
  Edvardson,S., Kose,S., Jalas, C., Fattal-Valevski,A., Watanabe, A., Ogawa, Y., Mamada, H., Fedick, A.M., Ben-Shachar, S., Treff, N.R., Shaag, A.,Bale, S., Gärtner, J., Imamoto, N., Elpeleg, O.
- Journal Title
  
  J. Med. Genet.
  
  Volume: 53 Issue: 2 Pages: 132-137
- DOI
  10.1136/jmedgenet-2015-103232
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440109, KAKENHI-INTERNATIONAL-15K21744
[Journal Article] Leukoencephalopathy and early death associated with an Ashkenazi-Jewish founder mutation in the Hikeshi gene.2016
- Author(s)
  Edvardson, S., Kose, S., Jalas, C., Fattal-Valevski, A., Watanabe, A., Ogawa, Y., Mamada, H., Fedick, A.M., Ben-Shachar, S., Treff, N.R., Shaag, A., Bale, S., Gartner, J., Imamoto, N., Elpeleg, O.
- Journal Title
  
  J Med Genet
  
  Volume: 53 Pages: 132-137
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26251021
[Journal Article] Leukoencephalopathy and early death associated with an Ashkenazi-Jewish founder mutation in the Hikeshi gene.2016
- Author(s)
  Edvardson, S., Kose, S., Jalas, C., Fattal-Valevski, A., Watanabe, A., Ogawa, Y., Mamada, H., Fedick, A.M., Ben-Shachar, S., Treff, N.R., Shaag, A., Bale, S., Gärtner, J., Imamoto, N., Elpeleg, O.
- Journal Title
  
  J. Med. Genet.
  
  Volume: 53 Pages: 132-137
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26251021
[Journal Article] Molecular mechanism by which acyclic retinoid induces nuclear localization of transglutaminase 2 in human hepatocellular carcinoma cells2015
- Author(s)
  Shrestha, R., Tatsukawa, H., Shrestha, R., Ishibashi, N., Matsuura, T., Kagechika, H., Kose, S., Hitomi, K., Imamoto, N., Kojima S.
- Journal Title
  
  Cell Death. Dis.
  
  Volume: 6 Issue: 12 Pages: e2002-e2002
- DOI
  10.1038/cddis.2015.339
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440109
[Journal Article] Structural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70.2015
- Author(s)
  Song J, *Kose S, Watanabe A, Son SY, Choi S, Hong H, Yamashita E, Park I Y, *Imamoto N, *Lee S J.
- Journal Title
  
  Acta Cryst. D Biol. Crystallogr.
  
  Volume: 71(Pt3) Pages: 473-483
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26251021
[Journal Article] Structural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70s.2015
- Author(s)
  Song, J., Kose, S., Watanabe, A., Son, S.Y., Choi, S., Hong, H., Yamashita, E., Park, I.Y., Imamoto, N., Lee, S.J.
- Journal Title
  
  Acta Crystallogr. D Biol. Crystallogr.
  
  Volume: 71 Pages: 473-483
- Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26251021
[Journal Article] Molecular mechanism by which acyclic retinoid induces nuclear localization of transglutaminase 2 in human hepatocellular carcinoma cells.2015
- Author(s)
  Shrestha, R., Tatsukawa, H., Shrestha, R., Ishibashi, N., Matsuura, T., Kagechika, H., Kose, S., Hitomi, K., Imamoto, N., Kojima, S.
- Journal Title
  
  Cell Death Disease
  
  Volume: 6
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26251021
[Journal Article] Reconstitution of nucleocytoplasmic transport using digitonin-permeabilized cells2015
- Author(s)
  Kose, S., Funakoshi, T., Imamoto, N.
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 1262 Pages: 291-303
- DOI
  10.1007/978-1-4939-2253-6_18
- ISBN
  9781493922529, 9781493922536
- Data Source
  KAKENHI-PROJECT-26440109
[Journal Article] Structural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70s.2015
- Author(s)
  Song J, Kose S, Watanabe A, Son SY, Choi S, Hong H, Yamashita E, Park IY, Imamoto N, Lee SJ.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr.
  
  Volume: 71 Issue: 3 Pages: 473-483
- DOI
  10.1107/s1399004714026881
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22121006, KAKENHI-PROJECT-26440109
[Journal Article] The Schizosaccharomyces pombe Hikeshi/Opi10 protein has similar biochemical functions to its human homolog but acts in different physiological contexts.2014
- Author(s)
  Oda, Y., Kimura, M., Kose, S., Fasken, M.B., Corbett, A.H., Imamoto, N.
- Journal Title
  
  FEBS Lett.
  
  Volume: 印刷中 Issue: 10 Pages: 304-4
- DOI
  10.1016/j.febslet.2014.04.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570242, KAKENHI-PROJECT-26440109
[Journal Article] Nucleocytoplasmic transport under stress conditions and its role in HSP70 chaperone systems.2014
- Author(s)
  Kose S, *Imamoto N.
- Journal Title
  
  BBA-General Subjects
  
  Volume: 1840 Pages: 2953-2960
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26251021
[Journal Article] The Schizosaccharomyces pombe Hikeshi/Opi10 protein has similar biochemical functions to its human homolog but acts in different physiological contexts.2014
- Author(s)
  Oda Y, Kimura M, Kose S, Fasken MB, Corbett AH, *Imamoto N.
- Journal Title
  
  FEBS Lett.
  
  Volume: 588 Pages: 1899-1905
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26251021
[Journal Article] Analysis of nucleocytoplasmic transport in digitonin-permeabilized cells under different cellular conditions2014
- Author(s)
  Furuta, M., Kose, S., Kehlenbach, R.H., Imamoto, N.
- Journal Title
  
  Methods Cell Biol.
  
  Volume: 122 Pages: 331-352
- DOI
  10.1016/b978-0-12-417160-2.00015-1
- Data Source
  KAKENHI-PROJECT-26440109
[Journal Article] Nucleocytoplasmic transport under stress conditions and its role in HSP70 chaperone systems2014
- Author(s)
  Kose, S., Imamoto, N.
- Journal Title
  
  Biochim. Biophys. Acta.
  
  Volume: 1840 Issue: 9 Pages: 2953-2960
- DOI
  10.1016/j.bbagen.2014.04.022
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26440109
[Journal Article] Identification of cargo proteins specific for the nucleocytoplasmic transport carrier transportin by combination of an in vitro transport system and stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteomics.2013
- Author(s)
  Kimura Makoto
- Journal Title
  
  Molecular & Cellular Proteomics
  
  Volume: 12 Issue: 1 Pages: 145-157
- DOI
  10.1074/mcp.m112.019414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J08344, KAKENHI-PROJECT-23570164, KAKENHI-PROJECT-23570242
[Journal Article] Identification of cargo proteins specific for importin-β with importin-α applying a stable isotope labeling by amino acids in cell culture (SILAC)-based in vitro transport system.2013
- Author(s)
  Kimura M, Okumura N, Kose S, Takao T, Imamoto N,
- Journal Title
  
  J.Biol. Chem.
  
  Volume: 288 Issue: 34 Pages: 24540-24549
- DOI
  10.1074/jbc.m113.489286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570164, KAKENHI-PROJECT-23570242
[Journal Article] Hikeshi, a nuclear import carrier for Hsp70s, protects cells from heat-shock induced nuclear damage2012
- Author(s)
  Kose, S., Furuta, M., Imamoto, N.
- Journal Title
  
  Cell
  
  Volume: 149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570242
[Journal Article] Heat-shock stress activates a novel nuclear import pathway mediated by Hikeshi2012
- Author(s)
  Imamoto, N., and Kose, S.
- Journal Title
  
  Nucleus
  
  Volume: 3 Issue: 5 Pages: 422-428
- DOI
  10.4161/nucl.21713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570242
[Journal Article] Hikeshi, a nuclear import carrier for Hsp70s, protects cells from heat-shock induced nuclear damage2012
- Author(s)
  Kose, S., Furuta, M., and Imamoto, N.
- Journal Title
  
  Cell
  
  Volume: 27, 149 Issue: 3 Pages: 578-589
- DOI
  10.1016/j.cell.2012.02.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570242
[Journal Article] A live imaging system for visualizing nuclear pore complex (NPC) formation during interphase in mammalian cells.2010
- Author(s)
  Iino, H., Maeshima, K., Nakatomi, R., Kose, S., Hashikawa, T., Tachibana, T., Imamoto, N.
- Journal Title
  
  Genes Cells (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770166
[Journal Article] Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport.2009
- Author(s)
  Kosako, H., Yamaguchi, N., Aranami, C., Ushiyama, M., Kose, S., Imamoto, N., Taniguchi, H., Nishida, E., Hattori, S.
- Journal Title
  
  Nat. Struct. Mol. Biol. 16
  
  Pages: 1026-1035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770166
[Journal Article] Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain.2008
- Author(s)
  Hatayama, M., Tomizawa, T., Sakai-Kato, K., Bouvagnet, P., Kose, S., Imamoto, N., Yokoyama, S., Utsunomiya-Tate, N., Mikoshiba, K., Kigawa, T., Aruga J.
- Journal Title
  
  Hum. Mol. Genet. 17
  
  Pages: 3459-3473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770166
[Journal Article] The 70-kD heat shock cognate protein(hsc70) facilitates the nuclear export of the import receptors2005
- Author(s)
  Shingo Kose, Maiko Furuta, Makiko Koike, Yoshihiro Yoneda, Naoko Imamoto
- Journal Title
  
  J.Cell Biol. 171
  
  Pages: 19-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370090
[Journal Article] The 70-kD heat shock cognate protein (hsc70) facilitates the nuclear export of the import receptors.2005
- Author(s)
  Shingo Kose
- Journal Title
  
  J. Cell Biol. 171
  
  Pages: 19-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370090
[Journal Article] The 70-kD heat shock cognate protein (hsc70) facilitates the nuclear export of the import receptors2005
- Author(s)
  Shingo Kose
- Journal Title
  
  Journal of Cell Biology 171(1)
  
  Pages: 19-25
- Data Source
  KAKENHI-PROJECT-17028054
[Journal Article] Dissociation of heterochromatin protein 1 from lamin B receptor induced by human polyomavirus agnoprotein : role nuclear egress of viral particles2005
- Author(s)
  Yuki Okada, Tadaki Suzuki, Yuji Sunden, Yasuko Orba, Shingo Kose, Noko Imamoto, Hidehiro Takahashi, Shinya Tanaka, William W.Hall, Kazuo Nagashima, Hirofumi Sawa
- Journal Title
  
  EMBO Rep. 6
  
  Pages: 452-457
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370090
[Journal Article] Nuclear pore complex and nucleocytoplasmic transport2004
- Author(s)
  Shingo Kose, Naoko Imamoto
- Journal Title
  
  PROTEIN, NUCLEIC ACID AND ENZYME Vol.49
  
  Pages: 907-909
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370090
[Journal Article] 核膜孔複合体と核-細胞質問輸送2004
- Author(s)
  小瀬真吾
- Journal Title
  
  蛋白質核酸酵素 Vo1.49
  
  Pages: 907-909
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370090
[Journal Article] 核膜孔複合体と核-細胞質間輸送2004
- Author(s)
  小瀬真吾
- Journal Title
  
  蛋白質核酸酵素 46(7)
  
  Pages: 907-909
- Data Source
  KAKENHI-PROJECT-15032258
[Journal Article] 核膜孔複合体と核-細胞質間輸送2004
- Author(s)
  小瀬真吾
- Journal Title
  
  蛋白質核酸酵素 Vol.49・No.7
  
  Pages: 907-909
- Data Source
  KAKENHI-PROJECT-15370090
[Journal Article] β-Catenin shows an overlapping sequence requirement but distinct molecular interaction for its bi-directional passage through nuclear pores2004
- Author(s)
  Makiko Koike, Shingo Kose, Maiko Furuta, Naoko Taniguchi, Fumihiko Yokota, Yoshihiro Yoneda, Naoko Imamoto
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 34038-34047
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370090
[Journal Article] Architecture and Dynamics of Nuclear Pore Complex2004
- Author(s)
  Naoko Imamoto, Maiko Furuta, Makiko Koike, Shingo Kose
- Journal Title
  
  Dynamics of Cell Nucleus
  
  Pages: 195-201
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370090
[Journal Article] Heat-shock induced nuclear retention and recycling inhibition of importin α2004
- Author(s)
  Maiko Furuta, Shingo Kose, Makiko Koike, Takeshi Shimi, Yasushi Hiraoka, Yoshihiro Yoneda, Tokuko Haraguchi, Naoko Imamoto
- Journal Title
  
  Genes Cells 9
  
  Pages: 429-441
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370090
[Presentation] Hikeshiによる分子シャペロンHSP70の核移行とその機能2023
- Author(s)
  小瀬真吾、渡邊愛、今本尚子
- Organizer
  第17回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-19K06500
[Presentation] Hikeshiによる分子シャペロンHSP70の核輸送とその機能：転写活性制御と核タンパク質恒常性維持における役割2023
- Author(s)
  小瀬真吾、渡邊愛、今本尚子
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06500
[Presentation] HSP70核輸送運搬体分子Hikeshiが制御するストレス顆粒形成の解析2023
- Author(s)
  小瀬真吾、渡邊愛、今本尚子
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06500
[Presentation] HSP70核移行運搬体分子Hikeshiが制御する細胞ストレス応答とその役割2023
- Author(s)
  小瀬真吾、渡邊愛、今本尚子
- Organizer
  第75回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-19K06500
[Presentation] HikeshiによるHSP70核輸送：温度依存性、転写制御・核タンパク質恒常性機維持における役割2022
- Author(s)
  小瀬真吾、渡邊愛、今本尚子
- Organizer
  Biothermology Workshop 2022
- Invited
- Data Source
  KAKENHI-PROJECT-19K06500
[Presentation] Hikeshiによる分子シャペロンHSP70の核輸送が適切なHSF1転写制御とタンパク質恒常性維持に重要である2022
- Author(s)
  小瀬真吾、渡邊愛、今本尚子
- Organizer
  第16回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-19K06500
[Presentation] Hikeshiによる分子シャペロンHSP70核輸送：HSF1転写制御と核タンパク質恒常性機構における役割2022
- Author(s)
  小瀬真吾、渡邊愛、今本尚子
- Organizer
  第74回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-19K06500
[Presentation] Analysis of physiological functions of Hikeshi, a nuclear import factor of HSP702021
- Author(s)
  Shingo Kose, Naoko Imamoto
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06500
[Presentation] Analysis of physiological functions of Hikeshi, a nuclear import factor of HSP702021
- Author(s)
  Shingo Kose, Naoko Imamoto
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02442
[Presentation] Functional Analysis of Nuclear Transport Factor Hikeshi2020
- Author(s)
  今本尚子、小瀬真吾
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06500
[Presentation] 熱ショックタンパク質Hsp70の核内輸送を担うHikeshiの機能　細胞質の温度センシング機構の解明」2019
- Author(s)
  今本尚子、小瀬真吾、小川泰
- Organizer
  新学術領域研究「温度生物学」 2019年　冬の班会議
- Data Source
  KAKENHI-PROJECT-18H02442
[Presentation] 細胞核・細胞質の温度センシング機構の解明2019
- Author(s)
  今本尚子、小瀬真吾、小川泰
- Organizer
  新学術領域研究「温度生物学」 2019年　夏の班会議
- Data Source
  KAKENHI-PROJECT-18H02442
[Presentation] Hikeshiによる分子シャペロンHSP70核輸送とその機能2019
- Author(s)
  小瀬真吾
- Organizer
  第14回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-18H02442
[Presentation] Hikeshiが担うHsp70の核内機能の解析2019
- Author(s)
  今本尚子、小瀬真吾
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02442
[Presentation] Hikeshiによる分子シャペロンHSP70核輸送とその機能2019
- Author(s)
  小瀬真吾、今本尚子
- Organizer
  第14回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-19K06500
[Presentation] Hikeshiによる分子シャペロンHSP70核輸送：その分子メカニズムと細胞機能2019
- Author(s)
  小瀬真吾、渡邊愛、今本尚子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06500
[Presentation] 分子シャペロンHSP70の核内輸送運搬体Hikeshi：その輸送機構と生理機能について2018
- Author(s)
  小瀬真吾
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02442
[Presentation] Hikeshiノックアウト細胞における遺伝子発現変化とストレス応答の解析2017
- Author(s)
  小瀬真吾、渡邊愛、高木昌俊、儘田博志、今本尚子
- Organizer
  第34回染色体ワークショップ・第15回核ダイナミクス研究会合同開催
- Place of Presentation
  かずさアカデミアホール(千葉県木更津市)
- Year and Date
  2017-01-11
- Data Source
  KAKENHI-PROJECT-26440109
[Presentation] 細胞質から核への蛋白質輸送を担う12種類にimportinβファミリー輸送因子の基質の大規模同定2017
- Author(s)
  木村誠、森中祐理子、今井賢一郎、小瀬真吾、Paul Horton、今本尚子
- Organizer
  第34回染色体ワークショップ・第15回核ダイナミクス研究会
- Place of Presentation
  かずさアカデミアホール（千葉県木更津市）
- Year and Date
  2017-01-11
- Data Source
  KAKENHI-PROJECT-26251021
[Presentation] 核-細胞質間タンパク質運搬体分子Hikeshi: 熱ストレス時に活性化する分子シャペロンHSP70輸送機構とその生理機能2016
- Author(s)
  小瀬真吾、今本尚子
- Organizer
  第89回日本生化学会大会　シンポジウム「温度生物学の新展開」
- Place of Presentation
  東北大学川内キャンパス(宮城県仙台市)
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-26440109
[Presentation] Analysis of a stress activated nuclear import carrier, Hikeshi, using knockout mice.2016
- Author(s)
  儘田　博志、小林　健太郎、小瀬　真吾、今本　尚子
- Organizer
  第33回染色体ワークショップ・第14回核ダイナミクス研究会
- Place of Presentation
  松島一の坊（宮城郡松島町）
- Year and Date
  2016-01-14
- Data Source
  KAKENHI-PROJECT-26251021
[Presentation] 核―細胞質タンパク質運搬体分子Hikeshi:熱ストレス時に活性化する分子シャペロンHsp70輸送機構とその生理機能2016
- Author(s)
  小瀬真吾、今本尚子
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-26251021
[Presentation] 核-細胞質間輸送運搬体Hikeshiの機能：熱ストレス応答時における遺伝子発現変化の網羅的解析2016
- Author(s)
  小瀬真吾、高木昌俊、儘田博志、今本尚子
- Organizer
  第33回染色体ワークショップ・第14回核ダイナミクス研究会合同開催
- Place of Presentation
  宮城県宮城郡(松島一の坊)
- Year and Date
  2016-01-12
- Data Source
  KAKENHI-PROJECT-26440109
[Presentation] SILAC法と蛋白質核輸送再構成系によるimportin-βファミリー輸送因子の輸送基質の大規模同定2015
- Author(s)
  木村誠、小瀬真吾、今本尚子
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会・合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26251021
[Presentation] HSP70輸送分子Hikeshi：その構造と機能2015
- Author(s)
  小瀬真吾、Jinsue Song、渡邊愛、Soo Jae Lee、今本尚子
- Organizer
  第67回日本細胞生物学会大会
- Place of Presentation
  東京都江戸川区(タワーホール船堀)
- Year and Date
  2015-07-01
- Data Source
  KAKENHI-PROJECT-26440109
[Presentation] 熱ストレス依存的HSP70運搬体分子Hikeshi：その機能と遺伝性疾患2015
- Author(s)
  小瀬真吾、渡邊愛、今本尚子
- Organizer
  第38回日本分子生物学会年会/第88回日本生化学会大会合同大会
- Place of Presentation
  神戸市(神戸ポートアイランド)
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26440109
[Presentation] 分子シャペロンHSP70運搬体分子Hikeshiの輸送機構とその機能解析2014
- Author(s)
  小瀬真吾
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良市、日本
- Year and Date
  2014-06-11
- Data Source
  KAKENHI-PROJECT-26251021
[Presentation] HSP70分子シャペロンシステムにおける核-細胞質間運搬体分子Hikeshiの機能解析2014
- Author(s)
  小瀬真吾
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都市、日本
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26251021
[Presentation] Hikeshiによる熱ストレス依存的HSP70核内移行2014
- Author(s)
  小瀬真吾
- Organizer
  理研シンポジウム「細胞システムの動態と論理 VI」
- Place of Presentation
  和光市(理化学研究所)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 分子シャペロンHSP70運搬体分子Hikeshiの輸送機構とその機能解析2014
- Author(s)
  小瀬真吾、亀高愛、渡邊愛、本橋詳子、今本尚子
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良市(奈良県新公会堂)
- Year and Date
  2014-06-11
- Data Source
  KAKENHI-PROJECT-26440109
[Presentation] HSP70分子シャペロンシステムにおける核-細胞質間運搬体分子Hikeshiの機能解析2014
- Author(s)
  小瀬真吾、渡邊愛、儘田博志、高木昌俊、今本尚子
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都市(国立京都国際会館)
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26440109
[Presentation] 熱ストレス時に誘導される分子シャペロンHsp70のHikeshi依存的核内移行( Thermal stress-induced nuclear import of Hsp70 mediated)2013
- Author(s)
  小瀬真吾, 亀高愛, 本橋詳子, 渡邊愛, 今本尚子(理研・今本細胞核機能研究室)( Hikeshi Shingo Kose, Ai Kametaka, Shoko Motohashi, Ai Watanabe, Shoko Motohashi, Naoko Imamoto(Cellular Dynamics Laboratory, RIKEN))
- Organizer
  第36回日本分子生物学会年会. (The 36th Annual Meeting of the Molecular Biology Society of Japan)
- Place of Presentation
  神戸市(神戸ポートアイランド)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 核-細胞質間運搬体分子Hikeshi と分子シャペロンHsp70 の相互作用とその機能解析(Analysis of the interaction betweennuclear import carrier, Hikeshi, andmolecular chaperone Hsp70 and its cellular functionShingo Kose)2013
- Author(s)
  小瀬真吾, 渡邊愛, 亀高愛, 本橋詳子, 今本尚子. (理研・今本細胞核機能研究室) (Ai Watanabe, Ai Kametaka,Shoko Motohashi, Naoko Imamoto. (Cellular Dynamics Lab., RIKEN))
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜市(パシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] ストレス応答時の核-細胞質間タンパク質輸送:運搬体分子Hikeshiと分子シャペロンHsp70の分子間相互作用解析2013
- Author(s)
  小瀬真吾1, 亀高愛, 白燦基, 佐甲靖志, 今本尚子1
- Organizer
  第31回染色体ワークショップ・第12回核ダイナミクス研究会
- Place of Presentation
  神奈川県足柄下郡(ホテルおかだ)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] Hikeshi, a novel nuclear import carrier for Hsc70/Hsp70, protects cells from heat-shock induced nuclear damage2012
- Author(s)
  Shingo Kose, Maiko Furuta, Ai Watanabe, Ai Kametaka, Naoko Imamoto.
- Organizer
  第45回日本発生生物学会/第64回日本細胞生物学会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2012-05-31
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 熱ショック応答と核-細胞質間蛋白質輸送:新規運搬体分子"Hikeshi"の機能解析2012
- Author(s)
  小瀬真吾、亀高愛、白燦基、佐甲靖志、今本尚子
- Organizer
  理研シンポジウム「細胞システムの動態と論理 IV」
- Place of Presentation
  和光市(理化学研究所)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] Nuclear import receptor, Hikeshi, for Hsp70s is required for attenuation of heat-shock response and protecting cell damages from stress2012
- Author(s)
  Kose, S., Kametaka, A., Watanabe, A., and Imamoto, N.
- Organizer
  Dynamic Organization of Nuclear Function Meeting, Cold Spring Harbor
- Place of Presentation
  New York, USA
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 「細胞システムの動態と論理IV」熱ショック応答と核-細胞質間蛋白質輸送:新規運搬体分子"Hikeshi"の機能解析.2012
- Author(s)
  小瀬真吾, 亀高愛, 白燦基, 佐甲靖志, 今本尚子
- Organizer
  理研シンポジウム
- Place of Presentation
  和光市(理研) (ポスター)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] Nuclear import receptor, Hikeshi, for Hsp70s is required for attenuation of heat-shock response and protecting cell damages from stress2012
- Author(s)
  Kose, S., Kametaka, A., Watanabe, A., and Imamoto, N.
- Organizer
  Dynamic Organization of Nuclear Function Meeting
- Place of Presentation
  Cold Spring Harbor, New York
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 熱ストレス時に機能する核-細胞質間運搬体分子Hikeshiと分子シャペロンHsp70の機能2012
- Author(s)
  小瀬真吾, 亀高愛, 渡邊愛, 本橋詳子, 今本尚子 (理研・基幹研・今本細胞核機能研究室)
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 熱ショック時における分子シャペロンHsp70sの核内輸送経路とその機能2011
- Author(s)
  小瀬真吾, 今本尚子
- Organizer
  第10回核ダイナミクス研究会
- Place of Presentation
  北海道北広島市(札幌北広島クラッセホテル) (26日口頭)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 熱ショック応答時の核-細胞質間分子輸送：新規輸送経路同定とその機能解析に向けて2011
- Author(s)
  小瀬真吾
- Organizer
  理研シンポジウム「細胞システムの動態と論理 III」(招待講演)
- Place of Presentation
  理化学研究所(埼玉県)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 関東支部例会細胞ストレスと核-細胞質間分子輸送制御:新規運搬体分子の生化学的同定2011
- Author(s)
  小瀬真吾, 今本尚子
- Organizer
  平成23年度日本生化学会
- Place of Presentation
  新宿区(東京理科大) (口頭)
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 「細胞システムの動態と論理III」熱ショック応答時の核-細胞質間分子輸送:新規輸送経路同定とその機能解析に向けて2011
- Author(s)
  小瀬真吾
- Organizer
  理研シンポジウム
- Place of Presentation
  和光市(理研) (口頭)
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 細胞ストレスと核-細胞質間分子輸送制御：Hsp70の新規核内輸送経路とその機能2011
- Author(s)
  小瀬真吾、渡邊愛、今本尚子
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 細胞ストレスと核-細胞質間分子輸送制御：新規運搬体分子の生化学的同定2011
- Author(s)
  小瀬真吾、今本尚子
- Organizer
  日本生化学会関東支部例会(招待講演)
- Place of Presentation
  東京理科大(東京都)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 熱ショック時における分子シャペロンHsp70sの核内輸送経路とその機能2011
- Author(s)
  小瀬真吾、今本尚子
- Organizer
  第10回核ダイナミクス研究会
- Place of Presentation
  札幌北広島クラッセホテル(北海道)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 細胞ストレスと核-細胞質間分子輸送制御:Hsp70の新規核内輸送経路とその機能2011
- Author(s)
  小瀬真吾, 渡邊愛, 今本尚子
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都市(国立京都国際会館) (23日口頭)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] Analysis of nuclear import of molecular chaperone 70kDa heat shock cognate protein(Hsc70)2009
- Author(s)
  小瀬真吾
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20770166
[Presentation] Analysis of nuclear import of molecular chaperone 70kDa heat shock cognate protein (Hsc70)2009
- Author(s)
  小瀬真吾
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20059038
[Presentation] 熱シュック時における分子シャペロンHsc70の核内移行を促進するタンパク質の同定2009
- Author(s)
  小瀬真吾
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20770166
[Presentation] 熱シュック時における分子シャペロンHsc70の核内移行を促進するタンパク質の同定2009
- Author(s)
  小瀬真吾
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20059038
[Presentation] Analysis of nuclear import of molecular chaperone 70kDa heat shock cognate protein (Hsc70)2009
- Author(s)
  Shingo Kose, Naoko Imamoto
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋市
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20770166
[Presentation] 熱ショック時における分子シャペロンHsc70の核内移行を促進するタンパク質の同定Identification of a protein facilitating nuclear import of molecular chaperone Hsc70 under heat shock2009
- Author(s)
  小瀬真吾、今本尚子
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸市
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20770166
[Presentation] 分子シャペロンHsc70の核内移行機構の解析2009
- Author(s)
  小瀬真吾, 他
- Organizer
  バイオアーキテクト第3回ワークショップ
- Place of Presentation
  新潟
- Year and Date
  2009-01-24
- Data Source
  KAKENHI-PROJECT-19038027
[Presentation] 核-細胞質間輸送経路解析系の構築とストレスタンパク質hsc70の核内輸送機構の解析」第7回細胞核ダイナミクス研究会2007
- Author(s)
  小瀬真吾
- Organizer
  第7回細胞核ダイナミクス研究会
- Place of Presentation
  札幌
- Year and Date
  2007-09-26
- Data Source
  KAKENHI-PROJECT-18770182
[Presentation] 細胞分化における核-細胞質間分子輸送システムの変化と機能解析2007
- Author(s)
  小瀬真吾
- Organizer
  第40回発生生物学会、第59回日本細胞生物学会
- Place of Presentation
  福岡
- Year and Date
  2007-05-29
- Data Source
  KAKENHI-PROJECT-18770182
[Presentation] 核-細胞質間輸送システムアッセイ系の構築と、それを利用したストレスタンパク質hsc70の核内輸送機構の解析2007
- Author(s)
  小瀬真吾
- Organizer
  BMB2007(第30回日本分子生物学会年会、第80回日本生化学会大会)
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-18770182
[Presentation] 熱ストレス時に機能する核-細胞質間運搬体分子Hikeshiと分子シャペロンHsp70の機能
- Author(s)
  小瀬真吾、亀高愛、渡邊愛、本橋詳子、今本尚子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡市(福岡国際会議場,マリンメッセ福岡)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] Hikeshiによる熱ストレス依存的HSP70核内移行
- Author(s)
  小瀬真吾
- Organizer
  理研シンポジウム「細胞システムの動態と論理 VI」
- Place of Presentation
  和光市、日本
- Year and Date
  2014-04-03 – 2014-04-04
- Data Source
  KAKENHI-PROJECT-26251021
[Presentation] Hikeshiによる熱ストレス依存的HSP70核内移行
- Author(s)
  小瀬真吾
- Organizer
  理研シンポジウム「細胞システムの動態と論理 VI」
- Place of Presentation
  和光市(理研)
- Year and Date
  2014-04-03 – 2014-04-04
- Data Source
  KAKENHI-PROJECT-26440109
[Presentation] ストレス応答時の核-細胞質間タンパク質輸送：運搬体分子Hikeshiと分子シャペロンHsp70の分子間相互作用解析
- Author(s)
  小瀬真吾、亀高愛、白燦基、佐甲靖志、今本尚子
- Organizer
  第31回染色体ワークショップ・第12回核ダイナミクス研究会
- Place of Presentation
  神奈川県足柄下郡(ホテルおかだ)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] Hikeshi, a novel nuclear import carrier for Hsc70/Hsp70, protects cells from heat-shock induced nuclear damage
- Author(s)
  Shingo Kose, Maiko Furuta, Ai Watanabe, Ai Kametaka, Naoko Imamoto
- Organizer
  第45回日本発生生物学会/第64回日本細胞生物学会合同大会
- Place of Presentation
  神戸市(神戸コンベンションセンター)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 熱ストレス時に誘導される分子シャペロンHsp70のHikeshi依存的核内移行
- Author(s)
  小瀬真吾、亀高愛、本橋詳子、渡邊愛、今本尚子
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸市(神戸ポートアイランド)
- Data Source
  KAKENHI-PROJECT-23570242
[Presentation] 核-細胞質間運搬体分子Hikeshiと分子シャペロンHsp70の相互作用とその機能解析
- Author(s)
  小瀬真吾、渡邊愛、亀高愛、本橋詳子、今本尚子
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜市(パシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-23570242

1. IMAMOTO Naoko (20202145)

# of Collaborated Projects: 10 results

# of Collaborated Products: 28 results
2. TAKAGI Masatoshi (60324779)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 木村誠 (00290891)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. KOJIMA Soichi (10202061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAMAGUCHI Kanji (50381950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUURA Tomokazu (30199749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOIKE Makiko (30391949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. MAESHIMA Kazuhiro (00392118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MAMADA Hiroshi (90568734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 古田満衣子 (70392107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 谷口直子 (90360586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OGAWA Yutaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. LEE Soo Jae

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. EPELEG Orly

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 奥村宣明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 山下栄樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kose Shingo 小瀬 真吾

KOSE Shingo 小瀬 真吾

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Co-Researchers

Hikeshiが制御する分子シャペロンHSP70核内輸送の活性化機構Principal Investigator

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Nuclear function and stress response of HSP70 regulated by nucleocytoplasmic transport carrier HikeshiPrincipal Investigator

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Analysis of molecular mechanism and physiological functions of the stress-responsive nucleocytoplasmic transport mediated by HikeshiPrincipal Investigator

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Mechanism and function of a novel stress-induced nuclear import pathwayPrincipal Investigator

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Importin βファミリー分子が創りだす細胞内分子流通システムとその機能解析Principal Investigator

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Identification and analysis of nucleocytoplasmic transport pathway using our novel assay systemPrincipal Investigator

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細胞の増殖と停止・分化における核ー細胞質間タンパク質輸送機構の役割Principal Investigator

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核-細胞質間蛋白質輸送の制御:輸送経路のインタープレイと刺激応答に伴う変化Principal Investigator

Principal Investigator

Project Period (FY)

Kose Shingo 小瀬真吾

KOSE Shingo 小瀬真吾