Morita Akinori 森田明典

… Alternative Names

MORITA Akinori 森田明典

Less

Researcher Number	90334234
Other IDs
External Links
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 徳島大学, 大学院医歯薬学研究部(医学域), 教授 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(医学系), 教授 2015: 徳島大学, 大学院医歯薬学研究部, 教授 2013 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 准教授 2012: 広島大学, 原爆放射線医科学研究所, 助教 … More 2009 – 2010: Tokyo University of Science, 理工学部, 助教 2007: Tokyo University of Science, 理工学部, 助教 2006: 東京理科大学, 理工学部, 助手 2005: 東京大学, 大学院医学系研究科, 助手 2002 – 2005: 東京大学, 大学院・医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related / Radiation science Except Principal Investigator Basic Section 52040:Radiological sciences-related / Radiation science / Radiation science / Biological Sciences
Keywords	Principal Investigator 放射線防護剤 / アポトーシス / p53 / 分子標的創薬 / p53阻害剤 / DNA損傷 / オルトバナジン酸ナトリウム / 抗炎症剤 / 正常組織防護 / 細胞死 … More / p53制御剤 / 放射線併用抗腫瘍薬 / 抗炎症作用 / 有機合成 / 放射線治療 / p53調節剤 / 金属錯体 / 亜鉛キレート化剤 / オルトパナジン酸ナトリウム / カスパーゼ / カスペース / ミトコンドリア / p41誘導阻害剤 / p41特異的抗体 / p41 / 放射線誘発アポトーシス … More Except Principal Investigator p53 / JNK / DNA-PK / SAPK / シグナル伝達 / 細胞死 / c-myc / オルトバナジン酸ナトリウム / 血管内皮 / wortmannin / Heat sensitization / U937細胞 / p41 / XRCC4 / Wortmannin / 温熱 / MOLT-4細胞 / p41タンパク / 放射線誘発細胞死 / 妊孕性 / 放射線雄性不妊 / 遅発性放射線腸管障害 / 5-クロロ-8-キノリノール / 放射線腸管障害 / 血管内皮損傷 / 放射線骨髄障害 / 炎症 / 遅発性腸管障害 / バナデート / U937 cells / apoptosis / cell death / hyperthermia / 温熱療法 / セラミド / リン酸化特異抗体 / Akt / 温熱高感受性 / 細胞死、アポトーシス / p53 null / Apoptosis / Cell death / U937 Cells / Hyperthermia / 細胞応答シグナル / 放射線療法 / 応答特異抗体 / DNA array / アポトーシス / MOLT-4 / 放射線感受性 / 感受性 / c-Myc / 放射線 / 放射線誘発アポトーシス Less

Mechanism of action of sodium orthovanadate to inhibit radiation-induced male infertility
- Principal Investigator
  
  西山祐一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  The University of Tokushima
Development of Combination Radiation Therapy Drugs to Improve Cancer Control Rates by Regulating DNA Damage Response MoleculesPrincipal Investigator
- Principal Investigator
  
  森田明典
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  The University of Tokushima
A novel radioprotective mechanism of sodium orthovanadate and its application to radiotherapy
- Principal Investigator
  
  NISHIYAMA Yuichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  The University of Tokushima
Development of radioprotectors that selectively protect normal tissuesPrincipal Investigator
- Principal Investigator
  
  MORITA Akinori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  The University of Tokushima
Development of novel radioprotectors that target p53Principal Investigator
- Principal Investigator
  
  MORITA Akinori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  The University of Tokushima
Development of novel kind of radioprotectors that relieve the damage of normal tissues in radiation injuryPrincipal Investigator
- Principal Investigator
  
  MORITA Akinori
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Radiation science
- Research Institution
  The University of Tokushima
  Hiroshima University
Development of novel kind of p53 inhibitorsthat target the zincbinding site of p53Principal Investigator
- Principal Investigator
  
  MORITA Akinori
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Tokyo University of Science
効果的なp53阻害剤の開発Principal Investigator
- Principal Investigator
  
  森田明典
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Tokyo University of Science
細胞応答シグナルを利用する新放射線療法の開発
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  International University of Health and Welfare
オルトバナジン酸ナトリウムによる放射線誘発アポトーシス抑制機講の解明Principal Investigator
- Principal Investigator
  
  森田明典
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  The University of Tokyo
応答特異抗体とDNA arrayによる放射線感受性予測システムの構築
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  International University of Health and Welfare
  The University of Tokyo
放射線誘発アポトーシスにおけるp41機能の研究Principal Investigator
- Principal Investigator
  
  森田明典
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  The University of Tokyo
Clarification of response mechanism in U937 cells against heat treatment
- Principal Investigator
  
  SUZUKI Norio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  International University of Health and Welfare
  The University of Tokyo
放射線細胞応答メカニズムと感受性予測
- Principal Investigator
  
  SUZUKI Norio
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  International University of Health and Welfare
  The University of Tokyo

[Journal Article] Molecular Mechanisms of Acute Radiation Intestinal Injury and Its Control2024
- Author(s)
  Akinori Morita, Yuichi Nishiyama, Takuma Sakai, Yuichi Higashi
- Journal Title
  
  Radiation Environment and Medicine
  
  Volume: 13 Issue: 1 Pages: 10-18
- DOI
  10.51083/radiatenvironmed.13.1_10
- ISSN
  2423-9097, 2432-163X
- Year and Date
  2024-02-28
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07644, KAKENHI-PROJECT-23K27550
[Journal Article] 急性放射線腸管障害の分子機構とその制御2023
- Author(s)
  森田明典、西山祐一、坂井卓磨、東優一
- Journal Title
  
  放射線生物研究
  
  Volume: 58 Pages: 93-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K27550
[Journal Article] 急性放射線腸管障害の分子機構とその制御2023
- Author(s)
  森田明典、西山祐一、坂井卓磨、東優一
- Journal Title
  
  放射線生物研究
  
  Volume: 58 Pages: 93-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07644
[Journal Article] Isorhamnetin Promotes 53BP1 Recruitment through the Enhancement of ATM Phosphorylation and Protects Mice from Radiation Gastrointestinal Syndrome2021
- Author(s)
  Nishiyama Yuichi、Morita Akinori、Tatsuta Shogo、Kanamaru Misaki、Sakaue Masahiro、Ueda Kenta、Shono Manami、Fujita Rie、Wang Bing、Hosoi Yoshio、Aoki Shin、Sugai Takeshi
- Journal Title
  
  Genes
  
  Volume: 12 Issue: 10 Pages: 1514-1514
- DOI
  10.3390/genes12101514
- NAID
  120007164907
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03604, KAKENHI-PROJECT-20K05712, KAKENHI-PROJECT-21K07644
[Journal Article] A Novel RNA Synthesis Inhibitor, STK160830, Has Negligible DNA-Intercalating Activity for Triggering A p53 Response, and Can Inhibit p53-Dependent Apoptosis2021
- Author(s)
  Morita Akinori、Ochi Shintaro、Satoh Hidetoshi、Ujita Shohei、Matsushita Yosuke、Tada Kasumi、Toyoda Mihiro、Nishiyama Yuichi、Mizuno Kosuke、Deguchi Yuichi、Suzuki Keiji、Tanaka Yoshimasa、Ueda Hiroshi、Inaba Toshiya、Hosoi Yoshio、Aoki Shin
- Journal Title
  
  Life
  
  Volume: 11 Issue: 10 Pages: 1087-1087
- DOI
  10.3390/life11101087
- NAID
  120007164908
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03604, KAKENHI-PROJECT-21H02948, KAKENHI-PROJECT-20K05712, KAKENHI-PROJECT-21K07644
[Journal Article] Evaluation of sodium orthovanadate as a radioprotective agent under total-body irradiation and partial-body irradiation conditions in mice2021
- Author(s)
  Nishiyama Yuichi、Morita Akinori、Wang Bing、Sakai Takuma、Ramadhani Dwi、Satoh Hidetoshi、Tanaka Kaoru、Sasatani Megumi、Ochi Shintaro、Tominaga Masahide、Ikushima Hitoshi、Ueno Junji、Nenoi Mitsuru、Aoki Shin
- Journal Title
  
  International Journal of Radiation Biology
  
  Volume: 97 Issue: 9 Pages: 1241-1251
- DOI
  10.1080/09553002.2021.1941377
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03604, KAKENHI-PROJECT-20K05712, KAKENHI-PROJECT-21K07644
[Journal Article] Protective Effects of p53 Regulatory Agents against High-LET Radiation-Induced Injury in Mice2020
- Author(s)
  A. Morita, B. Wang, K. Tanaka, T. Katsube, M. Murakami, T. Shimokawa, Y. Nishiyama, S. Ochi, H. Satoh, M. Nenoi and S. Aoki
- Journal Title
  
  Frontiers in Public Health
  
  Volume: 8
- DOI
  10.3389/fpubh.2020.601124
- NAID
  120006937553
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05712, KAKENHI-PROJECT-19H03604, KAKENHI-PROJECT-18F18412
[Journal Article] p53制御による放射線感受性修飾にもとづく防護剤開発2019
- Author(s)
  西山祐一、森田明典
- Journal Title
  
  放射線生物研究
  
  Volume: 54 Pages: 237-250
- NAID
  40022150181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03604
[Journal Article] Development of p53-targeting drugs that increase radioresistance in normal tissues2019
- Author(s)
  Ochi Shintaro、Nishiyama Yuichi、Morita Akinori
- Journal Title
  
  J. Med. Invest.
  
  Volume: 66 Issue: 3.4 Pages: 219-223
- DOI
  10.2152/jmi.66.219
- NAID
  130007732965
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03604
[Journal Article] Development of p53-targeting drugs that increase radioresistance in normal tissues.2019
- Author(s)
  S. Ochi, Y. Nishiyama, and A. Morita.
- Journal Title
  
  The Journal of Medical Investigation
  
  Volume: in press
- NAID
  130007732965
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10396
[Journal Article] A chemical modulator of p53 transactivation that acts as a radioprotective agonist.2018
- Author(s)
  Akinori Morita, Ippei Takahashi, Megumi Sasatani, Shin Aoki, Bing Wang, Shinya Ariyasu, Kaoru Tanaka, Tetsuji Yamaguchi, Akiko Sawa, Yurie Nishi, Tatsuro Teraoka, Shohei Ujita, Yosuke Kawate, Chihiro Yanagawa, Keiji Tanimoto, Atsushi Enomoto, Mitsuru Nenoi, Kenji Kamiya, Yasushi Nagata, Yoshio Hosoi and Toshiya Inaba
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 17 Issue: 2 Pages: 432-442
- DOI
  10.1158/1535-7163.mct-16-0554
- NAID
  120006552353
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10396, KAKENHI-PROJECT-17K00553, KAKENHI-PROJECT-17K08225, KAKENHI-PROJECT-17K10434, KAKENHI-PROJECT-26293271, KAKENHI-PROJECT-15K11252, KAKENHI-PROJECT-20K20310
[Journal Article] Bisdemethoxycurcumin enhances X-ray-induced apoptosis possibly through p53/Bcl-2 pathway.2017
- Author(s)
  A. Enomoto, J. Yamada, A. Morita, and K. Miyagawa.
- Journal Title
  
  Mutat. Res.
  
  Volume: 815 Pages: 1-5
- DOI
  10.1016/j.mrgentox.2016.12.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461880, KAKENHI-PROJECT-16K10396, KAKENHI-PROJECT-15H04902
[Journal Article] 正常組織の耐容線量を高める放射線防護剤の開発2017
- Author(s)
  森田明典, 氏田将平
- Journal Title
  
  四国医学雑誌
  
  Volume: 73 Pages: 249-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10396
[Journal Article] Checkpoint kinase 2 is dispensable for regulation of the p53 response but is required for G2/M arrest and cell survival in cells with p53 defects under heat stress2017
- Author(s)
  Furusawa Yukihiro、Yamanouchi Yuka、Iizumi Takashi、Zhao Qing-Li、Mitsuhashi Yohei、Morita Akinori、Enomoto Atushi、Tabuchi Yoshiaki、Kondo Takashi
- Journal Title
  
  Apoptosis
  
  Volume: 22 Issue: 10 Pages: 1225-1234
- DOI
  10.1007/s10495-017-1402-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10396, KAKENHI-PROJECT-17K10434, KAKENHI-PROJECT-15H04904
[Journal Article] Effects of chronic restraint-induced stress on radiation-induced chromosomal aberrations in mouse splenocytes.2016
- Author(s)
  T. Katsube, B. Wang, K. Tanaka, Y. Ninomiya, G. Vares, T. Kawagoshi, N. Shiomi, Y. Kubota, Q. Liu, A. Morita, T. Nakajima, and M. Nenoi
- Journal Title
  
  Mutation Research/Genetic Toxicology and Environmental Mutagenesis
  
  Volume: 813 Pages: 18-26
- DOI
  10.1016/j.mrgentox.2016.11.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10396, KAKENHI-PLANNED-15H05944
[Journal Article] Chronic restraint-induced stress has little modifying effect on radiation hematopoietic toxicity in mice.2015
- Author(s)
  Bing Wang, Kaoru Tanaka, Takanori Katsube, Yasuharu Ninomiya, Guillaume Vares, Qiang Liu, Akinori Morita, Tetsuo Nakajima, Mitsuru Nenoi
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 56 Issue: 5 Pages: 760-767
- DOI
  10.1093/jrr/rrv030
- NAID
  120006959730
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25340041, KAKENHI-PROJECT-24689050
[Journal Article] Design and synthesis of 8-hydroxyquinoline-based radioprotective agents.2014
- Author(s)
  S. Ariyasu, A. Sawa, A. Morita, K. Hanaya, M. Hoshi, I. Takahashi, B. Wang, and S. Aoki.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22 Issue: 15 Pages: 3891-3905
- DOI
  10.1016/j.bmc.2014.06.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24689050, KAKENHI-PROJECT-26460156
[Journal Article] AS-2, a novel inhibitor of p53-dependent apoptosis, prevents apoptotic mitochondrial dysfunction in a transcription-independent manner and protects mice from a lethal dose of ionizing radiation.2014
- Author(s)
  A. Morita, S. Ariyasu, B. Wang, T. Asanuma, T. Onoda, A. Sawa, K. Tanaka, I. Takahashi, S. Togami, M. Nenoi, T. Inaba and S. Aoki.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 450 Issue: 4 Pages: 1498-1504
- DOI
  10.1016/j.bbrc.2014.07.037
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24689050, KAKENHI-PROJECT-25340041
[Journal Article] Sodium orthovanadate (vanadate), a potent mitigator of radiation-induced damage to the hematopoietic system in mice.2013
- Author(s)
  B. Wang, K. Tanaka, A. Morita, Y. Ninomiya, K. Maruyama, K. Fujita, Y. Hosoi, and M. Nenoi.
- Journal Title
  
  Journal of Radiation Research
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24689050
[Journal Article] Evaluation of Zinc (II) chelators for inhibiting p53-mediated apoptosis.2013
- Author(s)
  A. Morita, S. Ariyasu, S. Ohya, I. Takahashi, B. Wang, K. Tanaka, T. Uchida, H. Okazaki, K. Hanaya, A. Enomoto, M. Nenoi, M. Ikekita, S. Aoki, and Y. Hosoi
- Journal Title
  
  Oncotarget
  
  Volume: 4 Pages: 2439-2450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24689050
[Journal Article] Inhibition of DNA-dependent protein kinase promotes ultrasound -induced cell death including apoptosis in human leukemia cells2012
- Author(s)
  Furusawa Y, Fujiwara Y, Hassan MA, Tabuchi Y, Morita A, Enomoto A,and Kondo T
- Journal Title
  
  Cancer Lett
  
  Volume: 322 Issue: 1 Pages: 107-112
- DOI
  10.1016/j.canlet.2012.02.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390229, KAKENHI-PROJECT-23390386, KAKENHI-PROJECT-23650303, KAKENHI-PROJECT-23650304, KAKENHI-PROJECT-24689050
[Journal Article] Cycloheximide suppresses radiation-induced apoptosis in MOLT-4 cells with Arg72 variant of p53 through translational inhibition of p53 accumulation.2011
- Author(s)
  A.Ito, A.Morita, S.Ohya, S.Yamamoto, A.Enomoto, M.Ikekita.
- Journal Title
  
  J.Radiat.Res. Article first published online
- NAID
  10028111380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791218
[Journal Article] バナデート:p53に作用する新しいタイプの放射線防護剤2010
- Author(s)
  森田明典, 他
- Journal Title
  
  RADIOISOTOPES
  
  Volume: 59巻 Pages: 459-462
- NAID
  10026799933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791218
[Journal Article] 科学教養講座「バナデート:アポトーシスを抑える新しいタイプの放射線防護剤」2010
- Author(s)
  森田明典、大谷聡一郎
- Journal Title
  
  理大科学フォーラム 27(12)
  
  Pages: 28-33
- NAID
  40017411562
- Data Source
  KAKENHI-PROJECT-21791218
[Journal Article] Design and synthesis of a fluorescent probe for Zn2+, 5,7-bis(N,N-dimethylaminosulfonyl)-8-hydroxyquinoline-pendant 1,4,7,10-tetraazacyclododecane and Zn2+-dependent hydrolytic and Zn2+-independent photochemical reactivation of its benzenesulfonyl-caged derivative.2010
- Author(s)
  R.Ohshima, M. Kitamura, A. Morita, M.Shiro, Y.Yamada, M.Ikekita, E.Kimura, S.Aoki.
- Journal Title
  
  Inorganie Chem. 49
  
  Pages: 888-899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791218
[Journal Article] バナデート:p53依存性アポトーシス制御による新しいタイプの放射線防護剤2010
- Author(s)
  田中薫、王冰、森田明典、池北雅彦
- Journal Title
  
  放射線科学 53(11)
  
  Pages: 15-19
- NAID
  40019063787
- Data Source
  KAKENHI-PROJECT-21791218
[Journal Article] バナデート:アポトーシスを抑える新しいタイプの放射線防護剤2010
- Author(s)
  森田明典、大谷聡一郎
- Journal Title
  
  理大科学フォーラム
  
  Volume: 27巻 Pages: 28-33
- Data Source
  KAKENHI-PROJECT-21791218
[Journal Article] バナデート:p53に作用する新しいタイプの放射線防護剤2010
- Author(s)
  森田明典、山元真一、池北雅彦、王冰、田中薫
- Journal Title
  
  RADIOISOTOPES 59
  
  Pages: 459-462
- NAID
  10026799933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791218
[Journal Article] バナデート:p53依存性アポトーシス制御による新しいタイプの放射線防護剤2010
- Author(s)
  田中薫、王冰、森田明典、池北雅彦
- Journal Title
  
  放射線科学
  
  Volume: 53巻11号 Pages: 15-19
- NAID
  40019063787
- Data Source
  KAKENHI-PROJECT-21791218
[Journal Article] Sodium orthovanadate inhibits p53-mediated apoptosis2010
- Author(s)
  Morita, A., et al.
- Journal Title
  
  Cancer Research VOL.70
  
  Pages: 257-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791218
[Journal Article] Edaravone, a known free radical scavenger, enhances X-ray-induced apoptosis at low concentrations.2010
- Author(s)
  N.Sasano, A.Enomoto, Y.Hosoi, Y.Katsumura, Y.Matsumoto, A.Morita, K.Shiraishi, K.Miyagawa, H.Igaki, K.Nakagawa.
- Journal Title
  
  Cancer lett. 293
  
  Pages: 53-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791218
[Journal Article] Sodium orthovanadate inhibits p53-mediated apoptosis.2010
- Author(s)
  A.Morita, S.Yamamoto, B.Wang, K.Tanaka, N.Suzuki, S.Aoki, A.Ito, T.Nanao, S.Ohya, M.Yoshino, J.Zhu, A.Enomoto, Y.Matsumoto, O.Funatsu, Y.Hosoi, M.Ikekita.
- Journal Title
  
  Caneer Res. 70
  
  Pages: 257-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791218
[Journal Article] Sodium orthovanadate suppresses DNA damage-induced caspase activation and apoptosis by inactivating p532006
- Author(s)
  Morita, A., et al.
- Journal Title
  
  Cell Death and Differentiation 13
  
  Pages: 499-511
- NAID
  130006999522
- Data Source
  KAKENHI-PROJECT-18790876
[Journal Article] Sodium orthovanadate suppresses DNA damage-induced caspase activation and apoptosis by inactivating p532006
- Author(s)
  Morita, A., et al.
- Journal Title
  
  Cell Death and Differentiation 13
  
  Pages: 499-511
- NAID
  130006999522
- Data Source
  KAKENHI-PROJECT-16790723
[Journal Article] アポトーシスシグナリングと放射線防護2005
- Author(s)
  森田明典他
- Journal Title
  
  放射線生物研究 40(4)
  
  Pages: 360-384
- NAID
  40007088108
- Data Source
  KAKENHI-PROJECT-16790723
[Journal Article] Sodium orthovanadate suppresses DNA damage-induced caspase activation and apoptosis by inactivating p53..2005
- Author(s)
  Morita, A.
- Journal Title
  
  Cell Death Diff 13
  
  Pages: 499-511
- NAID
  130006999522
- Data Source
  KAKENHI-PROJECT-16659325
[Presentation] 急性放射線誘発消化管症候群の分子機構とその制御2024
- Author(s)
  森田明典
- Organizer
  第24回菅原・大西記念癌治療増感シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K27550
[Presentation] 急性放射線性腸炎における直腸上皮幹細胞の動態2023
- Author(s)
  シャラミラゴシュ、森田明典、西山祐一、東優一、園山雄一郎
- Organizer
  日本放射線影響学会第66回大会
- Data Source
  KAKENHI-PROJECT-23K27550
[Presentation] 炎症誘発性プラットフォームを標的とする放射線防護剤の開発2023
- Author(s)
  森田明典、谷本大河、東優一、西山祐一、昌子紡己、村田貴嗣、小向杏佳、金井昭教、國井大誓、坂井卓磨、貞富凌、王冰、下川卓志、中田健也、武村直紀、齊藤達哉、稲葉俊哉、椎名勇
- Organizer
  第60回日本放射線腫瘍学会生物部会学術大会
- Data Source
  KAKENHI-PROJECT-23K27550
[Presentation] 炎症誘発性プラットフォームを標的とする放射線防護剤の開発2023
- Author(s)
  森田明典、谷本大河、東優一、西山祐一、昌子紡己、村田貴嗣、小向杏佳、金井昭教、國井大誓、坂井卓磨、貞富凌、王冰、下川卓志、中田健也、武村直紀、齊藤達哉、稲葉俊哉、椎名勇
- Organizer
  第60回日本放射線腫瘍学会生物部会学術大会
- Data Source
  KAKENHI-PROJECT-21K07644
[Presentation] 急性放射線性腸炎における直腸上皮幹細胞の動態2023
- Author(s)
  シャラミラゴシュ、森田明典、西山祐一、東優一、園山雄一郎
- Organizer
  日本放射線影響学会第66回大会
- Data Source
  KAKENHI-PROJECT-21K07644
[Presentation] A novel immunomodulatory compound that prevents sub-total body irradiation-induced intestinal death2021
- Author(s)
  Taiga Tanimoto, Akinori Morita, Yuichi Nishiyama, Takatsugu Murata, Anjyu Sakai, Akinori Kanai, Yuichi Higashi, Taisei Kunii, Takuma Sakai, Ryo Sadatomi, Bing Wang, Takashi Shimokawa, Kenya Nakata, Naoki Takemura, Tatsuya Saitoh, Toshiya Inaba, Isamu Shiina
- Organizer
  The 64th Annual Meeting of the Japan Radiation Research Society
- Data Source
  KAKENHI-PROJECT-21K07644
[Presentation] 抗炎症作用を有する新規化合物の放射線防護剤としての活性評価2021
- Author(s)
  谷本大河, 森田明典, 西山祐一, 村田貴嗣, 酒井杏樹, 金井昭教, 東優一, 越智進太郎, 國井大誓, 坂井卓磨, 貞富凌, 王冰, 下川卓志, 中田健也, 齊藤達哉, 稲葉俊哉, 椎名勇
- Organizer
  第58回生物部会学術大会・第49回放射線による制癌シンポジウム
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] p53を標的とした放射線防護剤の粒子線治療における役割2021
- Author(s)
  森田明典、王冰、田中薫、勝部孝則、村上正弘、下川卓志、西山祐一、越智進太郎、佐藤秀哉、根井充、青木伸
- Organizer
  第58回日本放射線腫瘍学会生物部会学術大会・第49回放射線による制癌シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K07644
[Presentation] A novel immunomodulatory compound that prevents sub-total body irradiation-induced intestinal death2021
- Author(s)
  Taiga Tanimoto, Akinori Morita, Yuichi Nishiyama, Takatsugu Murata, Anjyu Sakai, Akinori Kanai, Yuichi Higashi, Taisei Kunii, Takuma Sakai, Ryo Sadatomi, Bing Wang, Takashi Shimokawa, Kenya Nakata, Naoki Takemura, Tatsuya Saitoh, Toshiya Inaba and Isamu Shiina
- Organizer
  The 64th Annual Meeting of the Japan Radiation Research Society
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] 抗炎症作用を有する新規化合物の放射線防護剤としての活性評価2021
- Author(s)
  谷本大河、森田明典、西山祐一、村田貴嗣、酒井杏樹、金井昭教、東優一、越智進太郎、國井大誓、坂井卓磨、貞富凌、王冰、下川卓志、中田健也、齊藤達哉、稲葉俊哉、椎名勇
- Organizer
  第58回日本放射線腫瘍学会生物部会学術大会・第49回放射線による制癌シンポジウム
- Data Source
  KAKENHI-PROJECT-21K07644
[Presentation] Expression analysis of genes associated with the radioprotective effect of p53 modulator 5CHQ on acute intestinal radiation injury2021
- Author(s)
  Takuma Sakai, Akinori Morita, Akinori Kanai, Bing Wang, Atsushi Enomoto, Shohei Ujita, Shin Aoki, Hidetoshi Sato, Masahiro Sakaue, Yuichi Nishiyama, Toshiya Inaba
- Organizer
  The 5th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] p53を標的とした放射線防護剤の粒子線治療における役割2021
- Author(s)
  森田明典, 王冰, 田中薫, 勝部孝則, 村上正弘, 下川卓志, 西山祐一, 越智進太郎, 佐藤秀哉, 根井充, 青木伸
- Organizer
  第58回生物部会学術大会・第49回放射線による制癌シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] 抗炎症作用を有する新規化合物の腸炎制御剤としての活性評価2021
- Author(s)
  東優一, 森田明典, 西山祐一, 村田貴嗣, 酒井杏樹, 金井昭教, 谷本大河, 坂井卓磨, 中田健也, 武村直紀, 齊藤達哉, 稲葉俊哉, 椎名勇
- Organizer
  第29回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] 抗炎症作用を有する新規化合物の腸炎制御剤としての活性評価2021
- Author(s)
  東優一、森田明典、西山祐一、村田貴嗣、酒井杏樹、金井昭教、谷本大河、坂井卓磨、中田健也、武村直紀、齊藤達哉、稲葉俊哉、椎名勇
- Organizer
  第29回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07644
[Presentation] 放射線防護活性を有する 2-Oxopyrrole 類の設計・合成及び活性評価2019
- Author(s)
  佐藤秀哉, 越智進太郎, 水野皓介, 松下洋輔, 出口雄一, 鈴木啓司, 田中義正, 植田弘師, 稲葉俊哉, 細井義夫, 森田明典, 青木伸
- Organizer
  日本薬学会第139年回
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] Mechanism of action of p53-regulating anti-cell death compound discovered by chemical library screening.2019
- Author(s)
  Ochi Shintaro, Satoh Hidetoshi, Ujita Shohei, Tada kasumi, Yosuke Matsushita, MiIzuno Kosuke, Deguchi Yuichi, Suzuki Keiji, Tanaka Yoshimasa, Ueda Hiroshi, Inaba Toshiya, Hosoi Yoshio, Aoki Shin and Akinori Morita
- Organizer
  he 62th Annual Meeting of the Japan Radiation Research Society
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] p53阻害剤バナデートは亜全身照射後のマウス腸管障害を促進する2019
- Author(s)
  坂井卓磨, 西山祐一, 森田明典, 王冰, ラマダニードゥウィー, 佐藤秀哉, 川端凌矢, 田中薫, 笹谷めぐみ, 越智進太郎, 根井充, 青木伸
- Organizer
  第57回日本放射線腫瘍学会生物部会学術大会
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] Evaluation of the radioprotective effects of flavonoids.2019
- Author(s)
  Akinori Morita, Tatsuta Shogo, Sakaue Masahiro, Fujita Ria, Hanaya Kengo, Sugai Takeshi, Yuichi Nishiyama, Ochi Shintaro, Sakai Takuma, Wang Bing and Aoki Shin
- Organizer
  The 62th Annual Meeting of the Japan Radiation Research Society
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] The p53 inhibitor sodium orthovanadate is not effective in relieving acute gastrointestinal syndrome of subtotal-body irradiated mice.2019
- Author(s)
  Yuichi Nishiyama, Akinori Morita, Sakai Takuma, Ramadhani Dwi, Satoh Hidetoshi, Kawabata Ryoya, Tanaka Kaoru, Sasatani Megumi, Ochi Shintaro, Nenoi Mitsuru and Aoki Shin
- Organizer
  The 62th Annual Meeting of the Japan Radiation Research Society
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] p53制御による重粒子放射線防護効果2019
- Author(s)
  森田明典, 王冰, 田中薫, 勝部孝則, 村上正弘, 西山祐一, 越智進太郎, 寺岡達朗, 佐藤秀哉, 川端凌矢, 下川卓志, 根井充, 青木伸
- Organizer
  第57回日本放射線腫瘍学会生物部会学術大会
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] The radioprotector 5CHQ upregulates gene expression of radioprotective humoral factors in acute radiation-injured murine intestinal epithelium.2019
- Author(s)
  Sakai Takuma, Akinori Morita, Kanai Akinori, Wang Bing, Enomoto Atsushi, Ujita Shohei, Aoki Shin, Sato HIdetoshi, Kawabata Junya, Sakaue Masahito, Yuichi Nishiyama and Inaba Toshiya
- Organizer
  The 62th Annual Meeting of the Japan Radiation Research Society
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] p53制御剤による重粒子放射線防護効果2018
- Author(s)
  森田明典, 王冰, 田中薫, 勝部孝則, 村上正弘, 西山祐一, 越智進太郎, 寺岡達朗, ラマダニードゥウィー, 下川卓史, 根井充, 青木伸
- Organizer
  日本放射線影響学会第61回大会
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] 細胞死制御剤による重粒子放射線防護効果2018
- Author(s)
  森田明典, 王冰, 田中薫, 勝部孝則, 村上正弘, ラマダニードゥウィー, 下川卓志, 根井充, 越智進太郎, 西山祐一, 寺岡達朗, 青木伸
- Organizer
  第56回日本放射線腫瘍学会生物部会学術大会
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] 化合物ライブラリーから選抜されたp53依存性細胞死抑制剤の作用機構解析2018
- Author(s)
  越智進太郎, 佐藤秀哉, 氏田将平, 多田佳寿美, 松下洋輔, 水野皓介, 出口雄一, 鈴木啓司, 田中義正, 植田弘師, 稲葉俊哉, 細井義夫, 青木伸, 森田明典
- Organizer
  日本放射線影響学会第61回大会
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] p53調節剤5CHQの類縁体探索から見出された5QXの放射線防護活性評価2018
- Author(s)
  西山祐一, 國井大誓, 笹谷めぐみ, 寺岡達朗, 坂井卓磨, 西山祐一, 神谷研二, 王冰, 青木伸, 森田明典
- Organizer
  日本放射線影響学会第61回大会
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] 放射線防護剤5-chloro-8-quinolinolによる照射後のp53標的遺伝子発現変化の網羅的解析2018
- Author(s)
  氏田将平, 榎本敦, 川手耀介, 寺岡達朗, 青木伸, 森田明典
- Organizer
  第256回徳島医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] 細胞死制御剤による重粒子放射線防護効果のマウス個体レベルでの検討2018
- Author(s)
  森田明典, 王冰, 新井ひろみ, 田中薫, 勝部孝則, 村上正弘, ラマダニードゥウィー, 下川卓志, 根井充, 越智進太郎
- Organizer
  H29年度HIMAC共同利用研究成果発表会
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] Protective effects of p53-regulating agents against high-LET radiation-induced injury in mice2018
- Author(s)
  Yuichi Nishiyama, Akinori Morita, Wang Bing, Tanaka Kaoru, Katsube Takanori, Murakami Masahiro, Ochi Shintaro, Teraoka Tatsuro, Dwindling Ramadhani, Shimokawa Takashi, Neon Mitsuru and Aoki Shin
- Organizer
  2nd Technological Competency as Caring in the Health Sciences 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] 放射線防護剤5CHQの遺伝子発現調節作用の網羅的解析2018
- Author(s)
  坂井卓磨, 氏田将平, 榎本敦, 川手耀介, 西山祐一, 寺岡達朗, 青木伸, 王冰, 金井昭教, 稲葉俊哉, 森田明典
- Organizer
  日本放射線影響学会第61回大会
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] 医療応用を目指した正常組織の放射線防護2017
- Author(s)
  森田　明典
- Organizer
  第58回原子爆弾後障害研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] 5-クロロ-8-キノリノール誘導体の放射線防護活性評価2017
- Author(s)
  山川知晃, 寺岡達朗, 森田明典, 氏田将平, 青木伸
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] キノリノール骨格を持った放射線防護剤の設計，合成および活性評価2017
- Author(s)
  寺岡達朗, 西友里恵, 大和田勇人, 森田明典, 氏田将平, 山川知晃, 青木伸
- Organizer
  第61回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] ケミカルライブラリーから選抜されたp53制御性放射線防護剤の作用機構解析2017
- Author(s)
  越智進太郎, 氏田将平, 多田佳寿美, 松下洋輔, 水野皓介, 佐藤秀哉, 青木伸, 出口雄一, 鈴木啓司, 田中義正, 植田弘師, 稲葉俊哉, 細井義夫, 森田明典
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] Requirement of the 8-hydroxyl group in the 5-chloro-8-quinolinol for its action as a radioprotective agonist.2017
- Author(s)
  S. Ujita, A. Morita, S. Aoki, Y. Nishi, T. Teraoka, M. Sasatani, B. Wang, I. Takahashi, K. Tanaka, T. Yamakawa, M. Nenoi, K. Kamiya, and T. Inaba
- Organizer
  The 1st International Symposium of the network-type Joint Usage/ Research Center for Radiation Disaster Medical Science
- Place of Presentation
  広島大学広仁会館（広島県広島市）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] 亜鉛酵素研究・機械学習・ランダムスクリーニングに基づくp53制御性放射線防護剤の設計・合成・活性評価2017
- Author(s)
  青木伸, 寺岡達朗, 西友里恵, 佐藤秀哉, 水野皓介, 嵯峨裕, 氏田将平, 山川知晃, 越智進太郎, 大和田勇人, 王冰, 森田明典
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] 放射線防護剤5CHQによる照射後の遺伝子発現変化の網羅的解析2017
- Author(s)
  氏田将平, 榎本敦, 森田明典
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] 正常組織の耐容線量を高める放射線防護剤の開発2017
- Author(s)
  森田明典
- Organizer
  第255回徳島医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] p53 を標的とする放射線防護剤5-chloro-8-quinolinol の作用機構解析2016
- Author(s)
  氏田将平, 森田明典, 青木伸, 西友里恵, 寺岡達郎, 王冰, 笹谷めぐみ, 田中薫, 山川知晃, 根井充, 神谷研二, 稲葉俊哉
- Organizer
  日本放射線影響学会第59回大会
- Place of Presentation
  JMSアステールプラザ（広島県広島市）
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] A chemical modulator of p53 transactivation that acts as a radioprotective agonist.2016
- Author(s)
  A. Morita, I. Takahashi, S. Aoki, B. Wang, S. Ariyasu, M. Sasatani, K. Tanaka, T. Yamaguchi, K. Tanimoto, M. Nenoi, K. Kamiya, Y. Nagata, Y. Hosoi, and T. Inaba.
- Organizer
  4th international postgraduate conference on pharmaceutical sciences (iPoPs 2016)
- Place of Presentation
  東京理科大学　野田キャンパス（千葉県野田市）
- Year and Date
  2016-02-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] p53 標的創薬による放射線防護2016
- Author(s)
  森田明典, 高橋一平, 笹谷めぐみ, 青木伸, 王冰, 有安真也, 田中薫, 山口哲司, 谷本圭司, 根井充, 神谷研二, 永田靖, 細井義夫, 稲葉俊哉
- Organizer
  日本放射線影響学会第59回大会
- Place of Presentation
  JMSアステールプラザ（広島県広島市）
- Data Source
  KAKENHI-PROJECT-16K10396
[Presentation] p53標的創薬による放射線防護剤の開発2015
- Author(s)
  森田明典．
- Organizer
  放医研不定期講演会
- Place of Presentation
  放射線医学総合研究所（千葉県千葉市）
- Year and Date
  2015-02-13
- Invited
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] KH-3, a novel chemical modulator of p53, enhances p21 induction and protects mice from gastrointestinal death by abdominal irradiation.2015
- Author(s)
  A. Morita, I. Takahashi, S. Aoki, B. Wang, S. Ariyasu, M. Sasatani, K. Tanaka, T. Yamaguchi, K. Tanimoto, K. Kamiya, Y. Hosoi, Y. Nagata and T. Inaba.
- Organizer
  15th International Congress of Radiation Research.
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2015-05-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] がん放射線治療の副作用低減を目的とするp53標的放射線防護剤の開発．2015
- Author(s)
  青木　伸，森田　明典，王　冰，有安　真也，西　友里恵，寺岡　達朗，氏田　将平，福井　大智，田中　薫，田中　智博．
- Organizer
  第9回バイオ関連化学シンポジウム．
- Place of Presentation
  熊本大学工学部　黒髪南地区キャンパス（熊本県熊本市）
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] A potent mitigator of radiation-induced damage to the hematopoietic system in mice.2014
- Author(s)
  B. Wang, K. Tanaka, A. Morita and M. Nenoi.
- Organizer
  The 7th National Congress of Radiation Medicine and Protection and The 20th Anniversary Tournament of The Radiological Hygiene Commission, Chinese Society of Preventive Medicine．
- Place of Presentation
  長城酒店（中国重慶市）
- Year and Date
  2014-10-15
- Invited
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] KH-3, A Transcriptional Modulator of p53, Protects Mice From Radiation-Induced Gastrointestinal Syndrome.2014
- Author(s)
  I. Takahashi, A. Morita, S. Aoki, B. Wang, M. Sasatani, S. Ariyasu, K. Kenji, Y. Hosoi, Y. Nagata and T. Inaba.
- Organizer
  56th Annual Meeting of American Society for Radiation Oncology
- Place of Presentation
  Moscone Center (San Francisco, U.S.A.)
- Year and Date
  2014-09-14
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] 8-キノリノール誘導体AS-2のp53依存性アポトーシス抑制機構．2014
- Author(s)
  浅沼哲雄, 森田明典, 小野田貴祥, 有安真也, 王冰, 澤晶子, 田中薫, 高橋一平, 根井充, 稲葉俊哉, 青木伸．
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2014-10-02
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] 新規放射線防護剤候補化合物の活性評価．2014
- Author(s)
  小野田貴祥, 森田明典, 浅沼哲雄, 有安真也, 澤晶子, 王冰, 田中薫, 根井充, 青木伸．
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2014-10-02
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] A potent mitigator of radiation-induced damage to the hematopoietic system in mice.2014
- Author(s)
  B. Wang, K. Tanaka, A. Morita and M. Nenoi.
- Organizer
  First China International Symposium of Protective Agents Against Injury Induced by Ionizing Radiation.
- Place of Presentation
  中国医学科学院放射線医学研究所（中国天津市）
- Year and Date
  2014-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] 新規アポトーシス抑制剤KH-3の放射線防護活性評価．2014
- Author(s)
  森田明典, 高橋一平, 青木伸, 王冰, 有安真也, 笹谷めぐみ, 田中薫, 谷本圭司, 神谷研二, 細井義夫, 永田靖, 稲葉俊哉．
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2014-10-01
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] p53を標的とする新規放射線防護剤の開発2012
- Author(s)
  森田明典
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  東北大学川内北キャンパス(宮城県)
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] p53転写非依存性アポトーシス誘導経路に作用する8・キノリノール誘導体KH-13の作用機構解析2012
- Author(s)
  森田明典
- Organizer
  第50回日本放射線腫瘍学会生物部会学術大会
- Place of Presentation
  健康文化村カルチャーリゾートフェストーネ(沖縄県)
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] 放射線誘発アポトーシスの分子機構とそれを利用した防護剤に関する研究2010
- Author(s)
  森田明典
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都テルサ(京都府)(日本放射線影響学会奨励賞受賞講演)
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] p53転写非依存性アポトーシス誘導経路に特異的に作用する亜鉛キレート化剤の作用機構解析2010
- Author(s)
  内田孝俊、森田明典, 他
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都テルサ(京都府)
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] 亜鉛イオン(II)との錯体生成によって活性化されるアポトーシス誘導剤の設計と合成2010
- Author(s)
  青木伸、中村有香里、塚本雅登、高澤涼子、森田明典, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山県
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] 放射線誘発アポトーシスの分子機構とそれを利用した防護剤に関する研究(日本放射線影響学会奨励賞受賞講演)2010
- Author(s)
  森田明典
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都テルサ(京都府)
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] Vanadate : a novel type of radioprotectox acts by inhibiting both transcription-dependent and transcription-independent p53 apoptotic pathways2010
- Author(s)
  Akinori Morita
- Organizer
  5th TUS International Collaboration Workshop
- Place of Presentation
  Hotel Metropolitan Edmont(東京都)
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] バナデート:p53転写依存性・非依存性両経路に作用する新しいタイプの放射線防護剤2010
- Author(s)
  森田明典
- Organizer
  放医研研究会講演会
- Place of Presentation
  放射線医学総合研究所(千葉県)
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] Vanadate : anovel type of radioprotector acts by inhibiting both transcription-dependent and transcription-independent p53 apoptotic pathways.2010
- Author(s)
  Akinori Morita.
- Organizer
  5th TUS International Collaboration Workshop
- Place of Presentation
  Hotel Metropolitan Edmont(東京都)
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] タンパク質合成阻害剤シクロヘキシミドを用いたMOLT-4細胞におけるp53依存性放射線誘発アポトーシス経路の解析2010
- Author(s)
  伊藤あずさ、森田明典, 他
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都テルサ(京都府)
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] p53分子内の亜鉛イオン結合部位を標的とする新規阻害剤の開発2010
- Author(s)
  大谷聡一郎、森田明典, 他
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都テルサ(京都府)
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] オルトバナジン酸ナトリウム(バナデート)は、マウスにおいて全身照射後の障害に対して有効な緩和剤(Mitigator)である2010
- Author(s)
  王冰、田中薫、森田明典, 他
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都テルサ(京都府).
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] オルトバナジン酸ナトリウムによるp53転写非依存性アポトーシス抑制機構および放射線防護効果2010
- Author(s)
  森田明典, 他
- Organizer
  日本放射線影響学会第52回大会
- Place of Presentation
  広島市南区民文化センター(広島県)
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] オルトバナジン酸ナトリウム(バナデート)は、マウスにおいて全身照射後の障害に対して有効な緩和剤(Mitigator)である2010
- Author(s)
  王冰、田中薫、森田明典, 他
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都テルサ(京都府)
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] オルトバナジン酸ナトリウムによるp53転写非依存性アポトーシス抑制機構および放射線防護効果2009
- Author(s)
  森田明典, 他
- Organizer
  日本放射線影響学会第52回大会
- Place of Presentation
  広島市南区民文化センター
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-21791218
[Presentation] オルトバナジン酸ナトリウムによるp53転写非依存性アポトーシス抑制機構2007
- Author(s)
  森田明典, 他
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-18790876
[Presentation] p53制御による放射線防護
- Author(s)
  森田明典
- Organizer
  放医研不定期講演会
- Place of Presentation
  放射線医学総合研究所（千葉県千葉市）
- Invited
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] 放射線治療の副作用を低減させる薬剤の設計と合成
- Author(s)
  青木伸, 有安真也, 森田明典, 澤晶子, 高橋一平, 王冰, 星美里, 内田孝俊, 大谷聡一郎, 細井義夫
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  アステールプラザ（広島県広島市）
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] The Mechanism of A Novel Radioprotector, 8-Quinolinol Derivative KH-3.
- Author(s)
  I. Takahashi, A. Morita, S. Aoki, B. Wang, Y. Hosoi, Y. Kaneyasu, M. Kenjo, T. Kimura, Y. Murakami, and Y. Nagata
- Organizer
  55th Annual Meeting of American Society for Radiation Oncology
- Place of Presentation
  Georgia World Congress Center（Atlanta, U.S.A.）
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] 新規アポトーシス抑制剤KH-3の作用機構解析
- Author(s)
  高橋一平, 森田明典, 青木伸, 花屋賢悟, 有安真也, 王冰, 田中薫, 笹谷めぐみ, 谷本圭司, 細井義夫, 永田靖, 稲葉俊哉
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  ホテルクラウンパレス青森（青森県青森市）
- Data Source
  KAKENHI-PROJECT-24689050
[Presentation] p53を標的とする放射線防護剤の設計と合成
- Author(s)
  有安真也, 森田明典, 高橋一平, 王冰, 澤晶子, 星美里, 内田孝俊, 大谷聡一郎, 細井義夫, 青木伸
- Organizer
  第7回バイオ関連化学シンボジウム
- Place of Presentation
  名古屋大学東山キャンパス（愛知県名古屋市）
- Data Source
  KAKENHI-PROJECT-24689050

1. SUZUKI Norio (10010050)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. AOKI Shin (00222472)

# of Collaborated Projects: 4 results

# of Collaborated Products: 43 results
3. WANG Bing (10300914)

# of Collaborated Projects: 4 results

# of Collaborated Products: 41 results
4. ENOMOTO Atsushi (20323602)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. MATSUMOTO Yoshihisa (20302672)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NISHIYAMA Yuichi (80730598)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. 下川卓志 (20608137)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. 椎名勇 (40246690)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
9. 笹谷めぐみ (80423052)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 金井昭教 (60549567)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
11. 細井義夫 (50238747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 真板宣夫 (00404046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TOYOSHIMA Megumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. 根井充

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 田渕圭章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 近藤隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Morita Akinori 森田 明典

MORITA Akinori 森田 明典

Research Projects

Research Products

Co-Researchers

Mechanism of action of sodium orthovanadate to inhibit radiation-induced male infertility

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Combination Radiation Therapy Drugs to Improve Cancer Control Rates by Regulating DNA Damage Response MoleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel radioprotective mechanism of sodium orthovanadate and its application to radiotherapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of radioprotectors that selectively protect normal tissuesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel radioprotectors that target p53Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel kind of radioprotectors that relieve the damage of normal tissues in radiation injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel kind of p53 inhibitorsthat target the zincbinding site of p53Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

効果的なp53阻害剤の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞応答シグナルを利用する新放射線療法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

オルトバナジン酸ナトリウムによる放射線誘発アポトーシス抑制機講の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

応答特異抗体とDNA arrayによる放射線感受性予測システムの構築

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

放射線誘発アポトーシスにおけるp41機能の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of response mechanism in U937 cells against heat treatment

Principal Investigator

Project Period (FY)

Morita Akinori 森田明典

MORITA Akinori 森田明典