TAKEUCHI Yusuke 竹内有輔

Researcher Number	90336214
Affiliation (based on the past Project Information) *help	2004: 東北大, 薬学研究科(研究院), 助教授 2003: 東北大学, 大学院・薬学研究科, 助教授 2001: Kumamoto University School of Medicine, Pharmacology, Instructor, 医学部, 助手
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology Except Principal Investigator General pharmacology
Keywords	Principal Investigator 可変領域 / NG108-15細胞 / δアイソフォーム / 線条体 / カルモデュリン依存性プロテインキナーゼII / Ca^<2+> Except Principal Investigator long-term potentiation / CaMキナーゼII / scaffold protein / vanadium compound … More / calpain / brain edema / nitric oxide / calmodulin antagonist / myocardial ischemia / brain ischemia / ニトロチロシン / Forkhead transcription factor / Fasリガンド / プロテインキナーゼ / 虚血耐性 / 脳梗塞 / 遅発性神経細胞死 / Akt / バナジウム / 中大脳動脈閉塞モデル / カルモデュリン / 神経細胞死 / 脳保護薬 / バナジウム化合物 / カルパイン / 一酸化窒素 / 脳浮腫 / カルモデュリン阻害剤 / 心筋虚血 / 脳虚血 / cell model / brain-derived neurotrophic factor / NG108--15 cell / nuclear localization signal / dopamine D2 receptor / Ca^<2+> signaling / gene expression / CaM kivases / CaMキナーゼIIサブタイプ / 細胞モデル / Ca^<2+>シグナル / 脳由来神経栄養因子 / NG108-15細胞 / 異所性遺伝子発現 / 核移行シグナル / ドーパミンD2受容体 / CaMキナーゼ / SAPI02 / NE-dlg / CaM kinase II / NMDA receptor / postsynaptic density / excitatory synapse / カリウムチャネル / PDZドメイン / クラスタリング分子 / シナプス可塑性 / シナプス / scafold protein / 興奮性シナプス / 海馬 / ドーパミン受容体 / SAP102 / PSD-95 / NMDA受容体 Less

カルシウム・カルモデュリン依存性プロインキナーゼIIの細胞内局在決定機構の解析Principal Investigator
- Principal Investigator
  
  竹内有輔
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tohoku University
Drug development by signal transduction therapy in the ischemic brain injury.
- Principal Investigator
  
  FUKUNAGA Kohji
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
Establishment of cell models on transfection of functional protein and the study on brain signal transduction
- Principal Investigator
  
  MIYAMOTO Eishichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kumamoto University
Neuropharmacological studies of clustering molecules expressing in the excitatory synapses
- Principal Investigator
  
  FUKUNAGA Kohji
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kumamoto University

All 2005 2004 2003 2002

All Journal Article

[Journal Article] Cytoprotective effect of 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e) on ischemia/reperfusion-induced injury in the rat heart involves inhibition of fodrin breakdown and protein tyrosine nitration.2005
- Author(s)
  M.Hashimoto, Y.Takada, Y.Takeuchi, J.Kasahara, H.Hisa, Y.Shirasaki, K.Fukunaga
- Journal Title
  
  J.Pharmacol.Sci. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Differential subcellular distributions of Ca^<2+>/Calmodulin-Dependent Protein kinase II subunits.2004
- Author(s)
  Y.Takeuchi
- Journal Title
  
  J.Neurosci.Res. 75
  
  Pages: 480-490
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Dopamine D2 receptor activates extracellular signal-regulated kinase through the specific region in the third cytoplasmic loop.2004
- Author(s)
  Takeuchi, Y.
- Journal Title
  
  J.Neurochem. 89
  
  Pages: 1498-1507
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Different effects of five dopamine receptor subtypes on NF-κB activity in NG108-15 cells and mouse brain.2004
- Author(s)
  Y.Takeuchi
- Journal Title
  
  J.Neurochem. 88
  
  Pages: 41-50
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Differential subcellular distributions of Ca^<2+>/Calmodulin-Dependent Protein kinase II subunits.2004
- Author(s)
  Y.Takeuchi, K.Nomura, K.Fukunaga
- Journal Title
  
  J.Neurosci.Res. 75
  
  Pages: 480-490
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Different effects of five dopamine receptor subtypes on NF-κB activity in NG108-15 cells and mouse brain.2004
- Author(s)
  Y.Takeuchi, K.Fukunaga
- Journal Title
  
  J.Neurochem. 88
  
  Pages: 41-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Different activation of NF-κB by stimulation of dopamine D2L and D2S receptors through calcineurin activation.2004
- Author(s)
  Y.Takeuchi
- Journal Title
  
  J.Neurochem 90
  
  Pages: 155-163
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Up-regulation of endothelial nitric oxide synthase via phosphatidylinositol 3-kinase pathway contributes to ischemic tolerance in the CA1 subfield of gerbil hippocampus.2004
- Author(s)
  A.Hashiguchi, S.Yano, M.Morioka, J.Hamada, Y.Ushio, Y.Takeuchi, K.Fukunaga
- Journal Title
  
  J.Cereb.Blood Flow & Metab. 24
  
  Pages: 271-279
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Different activation of NF-κB by stimulation of dopamine D2L and D2S receptors through calcineurin activation.2004
- Author(s)
  Y.Takeuchi, K.Fukunaga
- Journal Title
  
  J.Neurochem. 90
  
  Pages: 155-163
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Different effects of five dopamine receptor subtypes on NF-κB activity in NG1O8-15 cells and mouse birain.2004
- Author(s)
  Takeuchi, Y.
- Journal Title
  
  J.Neurochem. 88
  
  Pages: 41-50
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Different activation of NF-κB by stimulation of dopamine D2L and D2S receptors through calcineurin activation.2004
- Author(s)
  Takeuchi, Y.
- Journal Title
  
  J.Neurochem. 90
  
  Pages: 155-163
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Dopamine D2 receptor activates extracellular signal-regulated kinase through the specific region in the third cytoplasmic loop.2004
- Author(s)
  Y.Takeuchi, K.Fukunaga
- Journal Title
  
  J.Neurochem. 89
  
  Pages: 1498-1507
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Dopamine D2 receptor activates extracellular signal-regulated kinase through the specific region in the third cytoplasmic loop.2004
- Author(s)
  Y.Takeuchi
- Journal Title
  
  J.Neurochem. 89
  
  Pages: 1498-1507
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Differential subcellular distributions of Ca^<2+>/Calmodulin-Dependent Protein kinase II subunits.2004
- Author(s)
  Takeuchi, Y.
- Journal Title
  
  J.Neurosci.Res. 75
  
  Pages: 480-490
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Involvement of calcium/calmodulin-dependent protein kinase II in the induction of mPer1.2003
- Author(s)
  K.Nomura, Y.Takeuchi, S.Yamaguchi, H.Okamura, K.Fukunaga
- Journal Title
  
  J.Neurosci.Res. 72
  
  Pages: 384-392
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Differential subcellular localiztion of two dopamine D2 receptor isoforms in transfected NG108-15 cells.2003
- Author(s)
  Y.Takeuchi, K.Fukunaga
- Journal Title
  
  J.Neurochem. 85
  
  Pages: 1064-1074
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Differential subcellular localiztion of two dopamine D2 receptor isoforms in transfected NG108-15 cells.2003
- Author(s)
  Y.Takeuchi
- Journal Title
  
  J.Neurochem. 85
  
  Pages: 1064-1074
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Differential regulationof NF-κB, SRE and CRE by dopamine D1 and D2 receptors in transfected NG108-15 cells.2003
- Author(s)
  Y.Takeuchi, Kohji Fukunaga
- Journal Title
  
  J.Neurochem. 85
  
  Pages: 729-739
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Differential regulation of NF-κB, SRE and CRE by dopamine D1 and D2 receptors in transfected NG108-15 cells.2003
- Author(s)
  Y.Takeuchi
- Journal Title
  
  J.Neurochem. 85
  
  Pages: 729-739
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Activation of the rat dopamine D2 receptor promoter by mitogen-activated protein kinase and Ca^<2+>/calmodulin-dependent protein kinase II pathways.2002
- Author(s)
  Y.Takeuchi
- Journal Title
  
  J.Neurochem. 83
  
  Pages: 784-796
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Analysis on the promoter region of exon IV-BDNF in NG108-15 cells.2002
- Author(s)
  Y.Takeuchi
- Journal Title
  
  J.Neurochem. 83
  
  Pages: 67-79
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Activation of Ca^<2+>/calmodulin-dependent protein kinase II and brain-derived neurotrophic factor gene expression by stimulation of dopamine D2 receptor in transfected NG108-15 cells.2002
- Author(s)
  Y.Takeuchi, K.Fukunaga, E.Miyamoto
- Journal Title
  
  J.Neurochem. 82
  
  Pages: 316-328
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Activation of the rat dopamine D2 receptor promoter by mitogen-activated protein kinase and Ca^<2+>/calmodulin-dependent protein kinase II pathways.2002
- Author(s)
  Y.Takeuchi, E.Miyamoto, K.Fukunaga
- Journal Title
  
  J.Neurochem. 83
  
  Pages: 784-796
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Analysis on the promoter region of exon IV-BDNF in NG108-15 cells.2002
- Author(s)
  Y.Takeuchi, E.Miyamoto, K.Fukunaga
- Journal Title
  
  J.Neurochem. 83
  
  Pages: 67-79
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Differential regulation of pituitary hormone secretion and gene expression by thyrotropin-releasing hormone. A role for mitogen-activated protein kinase signaling cascade in rat pituitary GH3 cells.2002
- Author(s)
  H.Kanasaki, T.Yonehara, H.Yamamoto, Y.Takeuchi, K.Fukunaga, K.Takahashi, K.Miyazaki, E.Miyamoto
- Journal Title
  
  Biol.Reproduction 67
  
  Pages: 107-113
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Ca^<2+>/calmodulin-dependent protein kinase II-dependent long-term potentiation in the rat suprachiasmatic nucleus and its inhibition by melatonin.2002
- Author(s)
  K.Fukunaga, K.Horikawa, S.Shibata, Y.Takeuchi, E.Miyamoto
- Journal Title
  
  J.Neurosci.Res. 70
  
  Pages: 799-807
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Regulation of gonadotropin α subunit gene expression by dopamine D2 receptor agonist in clonal mouse gonadotroph αT3-1 cells.2002
- Author(s)
  H.Kanasaki, T.Yonehara, Y.Yamada, K.Takahashi, K.Hata, R.Fujiwaki, H.Yamamoto, Y.Takeuchi, K.Fukunaga, E.Miyamoto, K.Miyazaki
- Journal Title
  
  Biol.Reproduction 67
  
  Pages: 1218-1224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370035
[Journal Article] Activation of Ca^<2+>/calmodulin-dependent protein kinase II and brain-derived neurotrophic factor gene expression by stimulation of dopamine D2 receptor in transfected NG108-15 cells.2002
- Author(s)
  Y.Takeuchi
- Journal Title
  
  J.Neurochem. 82
  
  Pages: 316-328
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370035

1. KASAHARA Jiro (10295131)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. FUKUNAGA Kohji (90136721)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
3. YAMAMOTO Hideyuki (60191433)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MIYAMOTO Eishichi (50109659)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MORIOKA Motohiro (20295140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. YANO Shigetoshi (60332871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 比佐博彰 (60192712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

TAKEUCHI Yusuke 竹内 有輔

Research Projects

Research Products

Co-Researchers

カルシウム・カルモデュリン依存性プロインキナーゼIIの細胞内局在決定機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Drug development by signal transduction therapy in the ischemic brain injury.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of cell models on transfection of functional protein and the study on brain signal transduction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neuropharmacological studies of clustering molecules expressing in the excitatory synapses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Author(s)

Journal Title

Description

Data Source

[Journal Article] Differential subcellular distributions of Ca^<2+>/Calmodulin-Dependent Protein kinase II subunits.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Dopamine D2 receptor activates extracellular signal-regulated kinase through the specific region in the third cytoplasmic loop.2004

Author(s)

Journal Title

Data Source

[Journal Article] Different effects of five dopamine receptor subtypes on NF-κB activity in NG108-15 cells and mouse brain.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Differential subcellular distributions of Ca^<2+>/Calmodulin-Dependent Protein kinase II subunits.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Different effects of five dopamine receptor subtypes on NF-κB activity in NG108-15 cells and mouse brain.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Different activation of NF-κB by stimulation of dopamine D2L and D2S receptors through calcineurin activation.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Up-regulation of endothelial nitric oxide synthase via phosphatidylinositol 3-kinase pathway contributes to ischemic tolerance in the CA1 subfield of gerbil hippocampus.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Different activation of NF-κB by stimulation of dopamine D2L and D2S receptors through calcineurin activation.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Different effects of five dopamine receptor subtypes on NF-κB activity in NG1O8-15 cells and mouse birain.2004

Author(s)

Journal Title

Data Source

[Journal Article] Different activation of NF-κB by stimulation of dopamine D2L and D2S receptors through calcineurin activation.2004

Author(s)

Journal Title

Data Source

[Journal Article] Dopamine D2 receptor activates extracellular signal-regulated kinase through the specific region in the third cytoplasmic loop.2004

TAKEUCHI Yusuke 竹内有輔