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Kakiuchi Chihiro  垣内 千尋

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KAKIUCHI Chihiro  垣内 千尋

垣内 千尋  カキウチ チヒロ

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Researcher Number 90342766
Other IDs
Affiliation (Current) 2025: 順天堂大学, 医学部, 先任准教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 順天堂大学, 医学部, 先任准教授
2021 – 2022: 順天堂大学, 医学部, 准教授
2012 – 2017: 東京大学, 医学部附属病院, 准教授
2011: 独立行政法人理化学研究所, 客員研究員
2003 – 2006: 独立行政法人理化学研究所, 精神疾患動態研究チーム, 研究員
2002: 理化学研究所, 精神疾患動態研究チーム, 研究員
Review Section/Research Field
Principal Investigator
Psychiatric science / Basic Section 52030:Psychiatry-related / Psychiatric science
Except Principal Investigator
Psychiatric science / Basic Section 52030:Psychiatry-related
Keywords
Principal Investigator
WFS1 / 統合失調症 / 双極性障害 / 双極症 / 小胞体ストレス / リンパ芽球 / XBP1 / DNAマイクロアレイ / WFS1 neuron / 気分安定薬 … More / リチウム / 網羅的mRNA発現解析 / mRNA発現 / 一卵性双生児不一致例 / ゲノム解析 / アドレノメジュリン / 小胞体ストレス応答 / GRP94 / GRP78 / AMPA型グルタミン酸受容体 / リンパ芽球様細胞 / 双生児不一致例 / 培養リンパ芽球 / 双生児 / DNA microarray / 不一致例 / 一卵性双生児 / バルプロ酸 / 小胞体ストレス反応 / 一卵性双生児疾患不一致例 … More
Except Principal Investigator
次世代シーケンサー / 遺伝統計 / 体細胞変異 / 双極症 / 双極性障害 / エクソーム / 一卵性双生児 / 多発家系 / 候補遺伝子 / 発達障害 / 精神疾患 / 神経画像 / 環境 / 遺伝 / 統合失調症 / 双生児 / 精神生理学 Less
  • Research Projects

    (10 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (11 People)
  •  The role of WFS1 in bipolar disorderPrincipal Investigator

    • Principal Investigator
      垣内 千尋
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Juntendo University
  •  Comprehensive investigation of rare germline and somatic mutations in bipolar disorder by large-scale sequencing analysis.

    • Principal Investigator
      Takata Atsushi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  The role of WFS1 for action mechanism of mood stabilizersPrincipal Investigator

    • Principal Investigator
      垣内 千尋
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Juntendo University
  •  Gene expression analysis in monozygotic twins discordant for schizophrenia and control twinsPrincipal Investigator

    • Principal Investigator
      Kakiuchi Chihiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      The University of Tokyo
  •  Search for the candidate genes for mental and developmental disorders by analyzing family and discordant twin samples

    • Principal Investigator
      Tochigi Mamoru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Teikyo University
  •  Genetic analysis of adrenomedullin in schizophreniaPrincipal Investigator

    • Principal Investigator
      KAKIUCHI Chihiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      The University of Tokyo
  •  Elucidating gene X environment interaction in the pathophysiology of schizophrenia using twin research

    • Principal Investigator
      KASAI Kiyoto
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Psychiatric science
    • Research Institution
      The University of Tokyo
  •  双極性障害における小胞体ストレス応答とAMPA型グルタミン酸受容体輸送の関連Principal Investigator

    • Principal Investigator
      垣内 千尋
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Psychiatric science
    • Research Institution
      The Institute of Physical and Chemical Research
  •  一卵性双生児統合失調症不一致例培養リンパ芽球の網羅的遺伝子発現探索Principal Investigator

    • Principal Investigator
      垣内 千尋
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Psychiatric science
    • Research Institution
      The Institute of Physical and Chemical Research
  •  一卵性双生児のリンパ芽球を用いた躁うつ病候補遺伝子の網羅的探索研究Principal Investigator

    • Principal Investigator
      垣内 千尋
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Psychiatric science
    • Research Institution
      The Institute of Physical and Chemical Research

All 2006 2005 Other

All Journal Article Presentation

  • [Journal Article] XBP1 induces WFS1 through an endoplasmic reticulum stress response element-like motif in SH-SY5Y cells2006

    • Author(s)
      Kakiuchi C, Ishiwata M, Hayashi A, Kato T
    • Journal Title

      Journal of Neurochemstry 97

      Pages: 545-555

    • Data Source
      KAKENHI-PROJECT-17689035
  • [Journal Article] Functional polymorphisms of HSPA5 : possible association with bipolar disorder2005

    • Author(s)
      Chihiro Kakiuchi et al.
    • Journal Title

      Biochem Biophys Res Commun 336(4)

      Pages: 1136-1143

    • Data Source
      KAKENHI-PROJECT-17689035
  • [Journal Article] XBP1 induces WFS1 through endoplasmic reticulum stress response element (ERSE)-like motif in SH-SY5Y cells

    • Author(s)
      Chihiro Kakiuchi et al.
    • Journal Title

      Journal of neurochemistry (in press)

    • Data Source
      KAKENHI-PROJECT-17689035
  • [Presentation] Evaluating detected rare variants of glycine cleavage system genes in schizophrenia with metabolomics profilings

    • Author(s)
      Yoshikawa A, Nishimura F, Tochigi M, Kawamura Y, Umekage T, Kato K, Sasaki T, Ohashi Y, Iwamoto K, Kasai K, Kakiuchi C
    • Organizer
      XXII World Congress on Psychiatric Genetics
    • Place of Presentation
      Copenhagen
    • Year and Date
      2014-10-12 – 2014-10-16
    • Data Source
      KAKENHI-PROJECT-26461725
  • [Presentation] Targeted re-sequencing of SLITRK1 in Japanese patients with Tourette syndrome using next-generation sequencing

    • Author(s)
      Inai A, Kuwabara H, Nishimura F, Kato K, Yousuke E, Shimada T, Furukawa M, Sasaki T, Tochigi M, Kakiuchi C, Kasai K, Kano Y
    • Organizer
      XXII World Congress on Psychiatric Genetics
    • Place of Presentation
      Copenhagen
    • Year and Date
      2014-10-12 – 2014-10-16
    • Data Source
      KAKENHI-PROJECT-26461725
  • [Presentation] 統合失調症病態におけるNMDA受容体スイッチング制御因子の遺伝学的検討

    • Author(s)
      吉川茜、西村文親、稲井彩、西岡将基、江里口洋介、高屋淳彦、栃木衛、河村代志也、梅景正、加藤佳代子、佐々木司、笠井清登、垣内千尋
    • Organizer
      第36回日本生物学的精神医学会年会
    • Place of Presentation
      奈良
    • Year and Date
      2014-09-29 – 2014-10-01
    • Data Source
      KAKENHI-PROJECT-26461725
  • 1.  KASAI Kiyoto (80322056)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  KATO Tadafumi (30214381)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  ABE Osamu (50302716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  Tochigi Mamoru (40456116)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  Takata Atsushi (90643693)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  桑原 斉 (50456117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  窪田 美恵 (90344035)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  SASAKI Tsukasa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 9.  IKEBUCHI Emi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  AKAHANE Akihisa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Nishimura Fumichika
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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