KAIFU Tomonori 海部知則

… Alternative Names

KAIFU TomonoriI 海部知則

海部知則カイフトモノリ

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Researcher Number	90343037
Other IDs	https://orcid.org/0000-0002-2614-1472
Affiliation (Current)	2025: 東北医科薬科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 東北医科薬科大学, 医学部, 講師 2016: 東北医科薬科大学, 医学部, 講師 2016: 東京理科大学, 生命医科学研究所, 助教 2015: 東京理科大学, 研究推進機構生命医科学研究所, 助教 2012 – 2014: 東京理科大学, 生命医科学研究所, 助教 2010 – 2011: 東京大学, 医科学研究所, 助教 2003 – 2004: 東北大学, 加齢医学研究所, 助手
Review Section/Research Field	Principal Investigator Basic Section 42040:Laboratory animal science-related / Laboratory animal science / Laboratory animal science / Neurochemistry/Neuropharmacology Except Principal Investigator Laboratory animal science / Basic Section 49070:Immunology-related / Immunology
Keywords	Principal Investigator C型レクチン受容体 / 自己免疫疾患 / 樹状細胞 / アシアロ糖鎖 / DCIR / Ｃ型レクチン受容体 / 恒常性維持 / 糖鎖 / 自然免疫 / 免疫制御 … More / 糖鎖リガンド / 糖鎖認識受容体 / 疾患動物モデル / 遺伝子改変マウス / リガンド / 骨代謝 / サイトカイン / 活性化シグナル / グリア細胞 / ミエリン形成 / オリゴデンドロサイト / DAP12 … More Except Principal Investigator サイトカイン / immunoregulation / GVHD / transplantation / autoimmunity / allergy / PIR / Ig-like receptor / 遺伝子改変マウス / C型レクチン / 炎症性疾患 / 抗体 / 糖鎖 / DCIR / gene targeting / Allergy / IgLR / MHC class I / dendritic cell / Th2 response / PIR-B / C型レクチン受容体 / 実験動物 / 免疫学 / C1qTNF / CTRP / IL-1 / 間接リウマチ / 関節リウマチ / Th17細胞 / 自己免疫疾患 / 疾患モデル動物 Less

自然免疫受容体DCIRを標的とした自己免疫、炎症性疾患治療の試み
- Principal Investigator
  
  Chung Soo・hyun
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tokyo University of Science
The project that elucidates the mechanism of immunological homeostasis by modification of terminal sugar structurePrincipal Investigator
- Principal Investigator
  
  海部知則
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Regulation immune responses by the interaction between DCIR and its ligandPrincipal Investigator
- Principal Investigator
  
  KAIFU Tomonori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
The physiological functions of a C-type lectin receptor and the relation with diseasesPrincipal Investigator
- Principal Investigator
  
  KAIFU Tomonori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tohoku Medical and Pharmaceutical University
  Tokyo University of Science
Establishment of an IL-1-related gene-manipulated mouse library and dissection of the gene-targeted mice, aiming at identifying new therapeutic targets for diseases
- Principal Investigator
  
  Iwakura Yoichiro
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo University of Science
創薬標的の探索を目指したIL-1関連遺伝子改変マウスライブラリーの作製研究
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo University of Science
Establishing a new animal model for ankylosing spondylolysis using DCIR deficient micePrincipal Investigator
- Principal Investigator
  
  KAIFU Tomonori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo University of Science
  The University of Tokyo
Establishment of an IL-1-related gene-manipulated mice library, aiming at uncovering pathophysiology of disease from a view point of systems biology
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
免疫系シグナル伝達分子DAP12によるオリゴデンドロサイト機能制御の解析Principal Investigator
- Principal Investigator
  
  海部知則
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tohoku University
IMMUNE REGULATION BY IMMUNOGLOBULIN-LIKE RECEPTORS
- Principal Investigator
  
  TAKAI Toshiyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  Tohoku University

All 2022 2021 2020 2016 2015 2014 2013 2012 2011 2003 Other

All Journal Article Presentation Book Patent

[Book] Dendritic Cell Immunoreceptor (DCIR): An ITIM-Harboring C-Type Lectin Receptor.2016
- Author(s)
  Tomonori Kaifu and Yoichiro Iwakura.
- Total Pages
  12
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 第1章インターロイキン「IL-18/33/36/37」サイトカイン・増殖因子キーワード事典2015
- Author(s)
  海部知則、岩倉洋一郎
- Total Pages
  3
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 炎症性サイトカインと骨破壊2012
- Author(s)
  海部知則, 岩倉洋一郎
- Publisher
  医学のあゆみ
- Data Source
  KAKENHI-PROJECT-23500489
[Journal Article] The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflammatory cytokine IL-172022
- Author(s)
  MAKUSHEVA Yulia、CHUNG Soo-Hyun、AKITSU Aoi、MAEDA Natsumi、MARUHASHI Takumi、YE Xiao-Qi、KAIFU Tomonori、SAIJO Shinobu、SUN Haiyang、HAN Wei、TANG Ce、IWAKURA Yoichiro
- Journal Title
  
  Exp. Anim.
  
  Volume: 71 Issue: 3 Pages: 288-304
- DOI
  10.1538/expanim.21-0191
- NAID
  130008158392
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21J01492, KAKENHI-PROJECT-21K07063, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-19K06471
[Journal Article] DCIR and its ligand asialo-biantennary N-glycan regulate DC function and osteoclastogenesis2021
- Author(s)
  Kaifu Tomonori、Yabe Rikio、Maruhashi Takumi、Chung Soo-Hyun、Tateno Hiroaki、Fujikado Noriyuki、Hirabayashi Jun、Iwakura Yoichiro
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 218 Issue: 12 Pages: 1-10
- DOI
  10.1084/jem.20210435
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-19K06471
[Journal Article] Analysis of the circulating myeloid‐derived suppressor cells during androgen deprivation therapy for prostate cancer2021
- Author(s)
  Kohada Yuki、Kaiho Yasuhiro、Takeda Kazuya、Kuromoto Akito、Ito Jun、Teishima Jun、Nakamura Yasuhiro、Kaifu Tomonori、Nakamura Akira、Sato Makoto
- Journal Title
  
  IJU Case Reports
  
  Volume: 4 Issue: 6 Pages: 367-370
- DOI
  10.1002/iju5.12351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09719, KAKENHI-PROJECT-19K06471
[Journal Article] Accelerated decline of physical strength in peroxiredoxin-3 knockout mice2016
- Author(s)
  Zhang YG, Wang L, Kaifu T, Li J, Li X, Li L.
- Journal Title
  
  Exp. Biol. Med. (Maywood)
  
  Volume: 241 Issue: 13 Pages: 1395-1400
- DOI
  10.1177/1535370216642039
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430095
[Journal Article] DCIR in the “osteo-immune” system.2015
- Author(s)
  1.Maruhashi T, Kaifu T, and Iwakura Y
- Journal Title
  
  Oncotarget
  
  Volume: 6 Issue: 33 Pages: 34051-2
- DOI
  10.18632/oncotarget.6043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430095
[Journal Article] Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor.2015
- Author(s)
  Seno, A., Maruhashi, T., Kaifu, T., Yabe, R., Fujikado, N., Ma, G., Ikarashi, T., Kakuta, S., and *Iwakura, Y.
- Journal Title
  
  Exp. Anim.
  
  Volume: 未定
- NAID
  130005069862
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor.2015
- Author(s)
  Seno, A., Maruhashi, T., Kaifu, T., Yabe, R., Fujikado, N., Ma, G., Ikarashi, T., Kakuta, S., and Iwakura, Y.
- Journal Title
  
  Exp. Anim.
  
  Volume: 64 Pages: 109-119
- NAID
  130005069862
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] DDCIR is important for bone homeostasis by regulating IFN-γ production in T cells.2015
- Author(s)
  Maruhashi T*, Kaifu T*, Yabe R, Seno A, Chung SH, Fujikado N, and Iwakura Y
- Journal Title
  
  J. Immunol.
  
  Volume: 194 Issue: 12 Pages: 5681-91
- DOI
  10.4049/jimmunol.1500273
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430095, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor2014
- Author(s)
  Seno A, Maruhashi T, Kaifu T, Yabe R, Fujikado N, Ma G, Ikarashi T, Kakuta S, Iwakura Y
- Journal Title
  
  Experimental Animals
  
  Volume: Epub
- NAID
  130005069862
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26430095
[Journal Article] Generation of a Tlx1(CreER-Venus) knock-in mouse strain for the study of spleen development.2014
- Author(s)
  Nakahara R, Kawai Y, Oda A, Nishimura M, Murakami A, Azuma T, Kaifu T, Goitsuka, R.
- Journal Title
  
  Genesis.
  
  Volume: 52 Issue: 11 Pages: 916-923
- DOI
  10.1002/dvg.22829
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PUBLICLY-25111513, KAKENHI-PROJECT-25292194, KAKENHI-PROJECT-26430095, KAKENHI-PROJECT-26660259
[Journal Article] B7-H6/NKp30 interaction: a mechanism of alerting NK cells against tumors2011
- Author(s)
  Kaifu T, Escalière B, Gastinel LN, Vivier E, Baratin M
- Journal Title
  
  Cell. Mol. Life. Sci
  
  Volume: 68(21) Pages: 3531-9
- Data Source
  KAKENHI-PROJECT-23500489
[Journal Article] B7-H6/NKp30 interaction: a mechanism of alerting NK cells against tumors2011
- Author(s)
  Kaifu T, Escalière B, Gastinel LN, Vivier E, Baratin M
- Journal Title
  
  Cell. Mol. Life. Sci.
  
  Volume: 68 Pages: 3531-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500489
[Journal Article] Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice.2003
- Author(s)
  Kaifu, T.^* et al.
- Journal Title
  
  J.Clin.Invest. 111(3)
  
  Pages: 323-332
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207014
[Journal Article] Signaling via immunoglobulin Fc receptors induces oligodendrocyte precursor cell differentiation.2003
- Author(s)
  Nakahara, J., Tan-Takeuchi, K., Seiwa, C, Gotoh, M., Kaifu, T., Ujike, A., Inui, M., Yagi, T., Aiso, S., Takai, T., Asou, H.
- Journal Title
  
  Dev.Cell 4(6)
  
  Pages: 841-852
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207014
[Journal Article] Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice.2003
- Author(s)
  Kaifu, T.*, Nakahara, J.*, Inui, M.*, Mishima, K., Momiyama, T., Kaji, M., Sugahara, A., Koito, H., Ujike-Asai, A., Nakamura, A., Kanazawa, K., Tan-Takeuchi, K., Iwasaki, K., Yokoyama, W.M., Kudo, A., Fujiwara, M., Asou, H., Takai, T.(*equal contributor)
- Journal Title
  
  J.Clin.Invest. 111(3)
  
  Pages: 323-332
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207014
[Patent] 樹状細胞免疫受容体活性化剤、樹状細胞免疫受容体活性化方法、破骨細胞形成抑制剤、破骨細胞形成抑制方法、樹状細胞分化・増殖阻害剤、樹状細胞分化・増殖阻害方法2014
- Inventor(s)
  岩倉洋一郎、海部知則、矢部力朗
- Industrial Property Rights Holder
  岩倉洋一郎、海部知則、矢部力朗
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-24220011
[Patent] 樹状細胞免疫受容体活性化剤、樹状細胞免疫受容体活性化方法、破骨細胞形成抑制剤、破骨細胞形成抑制方法、樹状細胞分化・増殖阻害剤、樹状細胞分化・増殖阻害方法。2014
- Inventor(s)
  岩倉洋一郎、海部知則、矢部力朗
- Industrial Property Rights Holder
  岩倉洋一郎、海部知則、矢部力朗
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-14
- Overseas
- Data Source
  KAKENHI-PROJECT-26430095
[Presentation] タイラーマウス脳脊髄炎ウイルス受容体に関与する糖脂質・糖タンパク質の解析2021
- Author(s)
  武田和也、姫田敏樹、海部知則、大原義朗、中村晃
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06471
[Presentation] タイラーマウス脳脊髄炎ウイルス受容体機能に関与する糖脂質の解析2021
- Author(s)
  武田和也、海部知則、中村晃
- Organizer
  第33回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06471
[Presentation] 進行非小細胞肺がん患者における抗PD-1治療の対する末梢血免疫細胞動態と臨床効果2021
- Author(s)
  吉村成央、大類孝、武田和也、海部知則、中村晃、跡部百合、佐々木高信、菅原崇史、田畑俊治
- Organizer
  第61回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K06471
[Presentation] Analysis of sialylated glycolipids and N-glycans between Theiler’s murine encephalomyelitis virus binding and non-binding cell.2021
- Author(s)
  Kazuya T, Kaifu T, Nakamura A.
- Organizer
  第50回日本免疫学会・学術集会
- Data Source
  KAKENHI-PROJECT-19K06471
[Presentation] Interaction of DCIR and asialo-N-glycan ameliorates experimental autoimmune encephalomyelitis by regulating DC function.2021
- Author(s)
  Kaifu T, Chung S-H, Nakamura A, Iwakura Y
- Organizer
  第50回日本免疫学会・学術集会
- Data Source
  KAKENHI-PROJECT-19K06471
[Presentation] Gタンパク質共役受容体の機能不全による中枢神経系自己免疫疾患の増悪化機序の解析2021
- Author(s)
  澤邊敦哉、中村晃、後飯塚僚、海部知則
- Organizer
  第195回日仏生物学会例会
- Data Source
  KAKENHI-PROJECT-19K06471
[Presentation] 自己免疫疾患におけるGタンパク質共役型受容体の機能解析2021
- Author(s)
  澤邊敦哉、中村晃、後飯塚僚、海部知則
- Organizer
  第85回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06471
[Presentation] C型レクチン受容体欠損による中枢神経系自己免疫疾患自然発症機序の解明2020
- Author(s)
  海部知則、武田和也、岩倉洋一郎、中村晃
- Organizer
  第67回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-19K06471
[Presentation] DCIR－糖鎖間相互作用による骨代謝制御機構2016
- Author(s)
  矢部力朗、海部知則、丸橋拓海、西城忍、舘野浩章、平林淳、岩倉洋一郎
- Organizer
  第35回日本糖質年会
- Place of Presentation
  高知市文化プラザかるぽーと
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] DCIR maintains bone homeostasis by regulating IFN-γ production in T cells.2015
- Author(s)
  Tomonori Kaifu, Takumi Maruhashi, Rikio Yabe, Soo-hyun Chung, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura.
- Organizer
  Third Annual Meeting of the International Cytokine & Interferon Society (ICIS).
- Place of Presentation
  Bamberg, Germany
- Year and Date
  2015-08-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] DCIR maintains bone homeostasis by regulating IFN-g; production in T cells.2015
- Author(s)
  Tomonori Kaifu, Takumi Maruhashi, Rikio Yabe, Soo-hyun Chung,N, Yoichiro Iwakura.
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] DCIR maintains bone homeostasis by regulating IFN-γ production in T cells2015
- Author(s)
  Tomonori Kaifu, Takumi Maruhashi, Rikio Yabe, Soo-hyun Chung,N, Yoichiro Iwakura.
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター・札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26430095
[Presentation] DCIR maintains bone homeostasis by regulating IFN-γ production in T cells2015
- Author(s)
  Tomonori Kaifu, Takumi Maruhashi, Rikio Yabe, Soo-hyun Chung, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
- Organizer
  International Immunology Society
- Place of Presentation
  Bamberg・Germany
- Year and Date
  2015-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430095
[Presentation] 東京理科大学生命医科学研究所実験動物研究部門における遺伝子改変マウス供給について2015
- Author(s)
  久保幸子、海部知則、岩倉洋一郎.
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都テルサ・京都
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26430095
[Presentation] C型レクチン受容体DCIR欠損マウスで認められた関節強直と骨量増加の病態解析2015
- Author(s)
  海部知則、丸橋拓海、矢部力朗、鄭琇絢、妹尾彬正、藤門範行、岩倉洋一郎
- Organizer
  日本リウマチ学会第2回JCRベーシックリサーチカンファレンス
- Place of Presentation
  東京大学
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] 東京理科大学生命医科学研究所実験動物研究部門における遺伝子改変マウス供給について.2015
- Author(s)
  久保幸子、海部知則、岩倉洋一郎
- Organizer
  第62回日本実験動物学会
- Place of Presentation
  京都テルサ
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] C型レクチン受容体DCIR欠損マウスで認められた関節強直と骨量増加の病態解析2015
- Author(s)
  海部知則、丸橋拓海、矢部力朗、鄭琇絢、妹尾彬正、藤門範行、岩倉洋一郎
- Organizer
  日本リウマチ学会第2回JCRベーシックリサーチカンファレンス
- Place of Presentation
  東京大学・東京
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26430095
[Presentation] 抑制性C型レクチン受容体DCIRによる骨代謝制御機構2014
- Author(s)
  海部知則
- Organizer
  IGMセミナー
- Place of Presentation
  北海道大学遺伝子病制御研究所、北海道
- Year and Date
  2014-06-18
- Invited
- Data Source
  KAKENHI-PROJECT-26430095
[Presentation] 抑制性C型レクチン受容体DCIRによる骨代謝制御機構2014
- Author(s)
  海部知則
- Organizer
  北海道大学　遺伝子病制御研究所　IGMセミナー
- Place of Presentation
  北海道大学、北海道
- Year and Date
  2014-06-18
- Invited
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] 抑制型Ｃ型レクチン受容体Dendritic Cell ImmunoReceptor (DCIR)とIFN-ｇによる骨代謝制御2014
- Author(s)
  海部知則
- Organizer
  第181回日仏生物学会例会
- Place of Presentation
  京都産業大学むすびわざ館、京都府
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] 抑制型Ｃ型レクチン受容体Dendritic Cell ImmunoReceptor (DCIR)とIFN-γによる骨代謝制御2014
- Author(s)
  海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎
- Organizer
  第181回日仏生物学会例会
- Place of Presentation
  京都産業大学むすびわざ館、京都
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-26430095
[Presentation] IFN-γ is an osteoblatogenic factor for increasing the bone volume in DCIR-deficient mice.2014
- Author(s)
  海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館、京都
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-26430095
[Presentation] DCIR 欠損マウスを用いたC型レクチン受容体による骨代謝制御機構の解明2013
- Author(s)
  海部知則, 丸橋拓海, 馬光宇, 矢部力朗, 妹尾彬正, 岩倉洋一郎
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR欠損マウスを用いたC型レクチン受容体による骨代謝制御機構の解明.2013
- Author(s)
  海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎.
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば国際会議場
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] Dendritic Cell ImmunoReceptor (DCIR) is a negative regulator in balancing bone metabolism2013
- Author(s)
  Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Yoichiro Iwakura
- Organizer
  International Immunology Society
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR欠損マウスを用いたC型レクチン受容体による骨代謝制御機構の解明2013
- Author(s)
  海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば国際会議場
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] 東京理科大学生命医科学研究所実験動物学研究部門における遺伝子改変マウスの供給について2013
- Author(s)
  久保幸子, 海部知則, 立石麻理子, 角田茂, 岩倉洋一郎
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] Dendritic Cell ImmunoReceptor (DCIR) is a negative regulator in balancing bone metabolism.2013
- Author(s)
  Kaifu T., Maruhashi T, Ma G, Yabe R, Seno A, Iwakura Y.
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] 東京理科大学生命医科学研究所実験動物学研究部門における遺伝子改変マウスの供給について2013
- Author(s)
  久保幸子、海部知則、立石麻理子、角田茂、岩倉洋一郎
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば国際会議場
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR is a negative regulator in osteoclastogenesis2012
- Author(s)
  Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
- Organizer
  The 15 th Congress of Asia Pacific League of Association for Rheumatology
- Place of Presentation
  Dead Sea, Jordan
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR is a negative regulator in osteoclastogenesis2012
- Author(s)
  Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
- Organizer
  The 15th Congress of Asia Pacific League of Association for Rheumatology
- Place of Presentation
  Dead Sea, Jordan
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] 新たな強直性脊椎炎モデル：DCIR欠損マウスの解析2012
- Author(s)
  丸橋拓海、海部知則、藤門範行、岩倉洋一郎
- Organizer
  第59回日本実験動物学会総会
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] Dendritic Cell ImmunoReceptor (DCIR) negatively regulates osteoclastogeneis2012
- Author(s)
  Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
- Organizer
  第41回日本免疫学会総会・学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] 新たな強直性脊椎炎モデル:DCIR 欠損マウスの解析2012
- Author(s)
  丸橋拓海, 海部知則, 藤門範行, 岩倉洋一郎
- Organizer
  第59回日本実験動物学会総会
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] Dendritic Cell ImmunoReceptor (DCIR) negatively regulates osteoclastogenesis2012
- Author(s)
  Kaifu, T.
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] Dendritic immunoreceptor (DCIR) is a negative regulator in osteoclastogenesis2012
- Author(s)
  Kaifu, T
- Organizer
  Basic and Clinical Review Course, The 15th Congress of Asia Pacific League of Associations for Rheumatology (APLAR 2012)
- Place of Presentation
  Dead Sea, Jordan
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] DCIR欠損マウスは強直性脊椎炎様の病態を示す2011
- Author(s)
  Maruhashi Takumi, Kaifu Tomonori, Ma guangyu, Seno Akimasa, Fujikado Noriyuki, Iwakura Yoichiro
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] Experimental autoimmune encephalomyelitis is aggravated in DCIR knockout mice2011
- Author(s)
  妹尾彬正, 海部知則, 藤門範行, 岩倉洋一郎
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIRリガンドの探索2011
- Author(s)
  矢部力朗、丸橋拓海、妹尾彬正、馬光宇、海部知則、舘野浩章、平林淳、岩倉洋一郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR, a C-type lectin receptor, is a new negative regulator in osteoclastogenesis2011
- Author(s)
  Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
- Organizer
  9th Joint Meeting of the ICS and ISICR
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR リガンドの探索2011
- Author(s)
  矢部力朗, 丸橋拓海, 妹尾彬正, 馬光宇, 海部知則, 舘野浩章, 平林淳, 岩倉洋一郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR, a C-type lectin receptor, is a new negative regulator in osteoclastogenesis2011
- Author(s)
  Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR 欠損マウスは強直性脊椎炎様の病態を示す2011
- Author(s)
  Maruhashi Takumi, Kaifu Tomonori, Ma guangyu, Seno Akimasa, Fujikado Noriyuki, Iwakura Yoichiro
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR deficient mice develop ankylosing spondylitis-like pathology in humans2011
- Author(s)
  Takumi Maruhashi, Noriyuki Fujikado, Tomonori Kaifu, Yoichiro Iwakura
- Organizer
  9th Joint Meeting of the ICS and ISICR
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR, a C-type lectin receptor, is a new negative regulator in osteoclas togenesis2011
- Author(s)
  Tomonori Kaifu
- Organizer
  9^<th> Joint Meeting of the ICS and ISICR
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] DCIR: A new therapeutic target for autoimmune disorders2011
- Author(s)
  Rikio Yabe, Guangyu Ma, Noriyuki Fujikado, Tomonori Kaifu, Takumi Maruhashi, Akimasa Seno and Yoichiro Iwakura
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR, a C-type lectin receptor, is a new negative regulator in osteoclas togenesis2011
- Author(s)
  Tomonori Kaifu
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ,千葉
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] DCIR : A new therapeutic target for autoimmune disorders2011
- Author(s)
  Rikio Yabe, Guangyu Ma, Noriyuki Fujikado, Tomonori Kaifu, Takumi Maruhashi, Akimasa Seno and Yoichiro Iwakura
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] DCIR欠損マウスで認められた骨量増加メカニズムの解明
- Author(s)
  海部知則
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌コンベンションセンター、北海道
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] Dendritic Cell ImmunoReceptor (DCIR) is a negative regulator in balancing bone metabolism
- Author(s)
  Kaifu T., Maruhashi T, Ma G, Yabe R, Seno A, Iwakura Y
- Organizer
  International Immunology Society
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-23500489
[Presentation] 抑制性C型レクチン受容体DCIRによるIFN-ｇを介した骨代謝制御機構
- Author(s)
  海部知則
- Organizer
  第79回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  北海道大学医学部学友会館フラテホール、北海道
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] IFN-γ is an osteoblatogenic factor for increasing the bone volume in DCIR-deficient mice.
- Author(s)
  海部知則
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館、京都府
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24220011
[Presentation] DCIR欠損マウスで認められた骨量増加メカニズムの解明
- Author(s)
  海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌コンベンションセンター、北海道
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26430095
[Presentation] 抑制性C型レクチン受容体DCIRによるIFN-γを介した骨代謝制御機構.
- Author(s)
  海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎
- Organizer
  第79回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  北海道大学医学部学友会館フラテホール、北海道
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-26430095
[Presentation] 東京理科大学生命医科学研究所実験動物研究部門における遺伝子改変マウス供給について.
- Author(s)
  久保幸子、海部知則、立石麻理子、岩倉洋一郎
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌コンベンションセンター、北海道
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26430095

1. IWAKURA Yoichiro (10089120)

# of Collaborated Projects: 5 results

# of Collaborated Products: 45 results
2. SAIJO Shinobu (60396877)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. CE Tang (00572166)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KAKUTA Shigeru (80345032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. FUJIKADO Noriyuki (90447334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KUSAKA Toshimasa (60466836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MA GUANGYU (60572162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKAI Toshiyuki (20187917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 島津朋之 (20616437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中村晃 (20344723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. Chung Soo・hyun (40712443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 中村保宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAIFU Tomonori 海部 知則

KAIFU TomonoriI 海部 知則

海部 知則 カイフ トモノリ

Research Projects

Research Products

Co-Researchers

自然免疫受容体DCIRを標的とした自己免疫、炎症性疾患治療の試み

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

The project that elucidates the mechanism of immunological homeostasis by modification of terminal sugar structurePrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Regulation immune responses by the interaction between DCIR and its ligandPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

The physiological functions of a C-type lectin receptor and the relation with diseasesPrincipal Investigator

Principal Investigator

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Research Institution

Establishment of an IL-1-related gene-manipulated mouse library and dissection of the gene-targeted mice, aiming at identifying new therapeutic targets for diseases

Principal Investigator

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Research Institution

創薬標的の探索を目指したIL-1関連遺伝子改変マウスライブラリーの作製研究

Principal Investigator

Project Period (FY)

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Research Institution

Establishing a new animal model for ankylosing spondylolysis using DCIR deficient micePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Establishment of an IL-1-related gene-manipulated mice library, aiming at uncovering pathophysiology of disease from a view point of systems biology

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

免疫系シグナル伝達分子DAP12によるオリゴデンドロサイト機能制御の解析Principal Investigator

Principal Investigator

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Research Field

Research Institution

IMMUNE REGULATION BY IMMUNOGLOBULIN-LIKE RECEPTORS

Principal Investigator

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Research Institution

[Book] Dendritic Cell Immunoreceptor (DCIR): An ITIM-Harboring C-Type Lectin Receptor.2016

Author(s)

Total Pages

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Data Source

[Book] 第1章 インターロイキン「IL-18/33/36/37」 サイトカイン・増殖因子キーワード事典2015

Author(s)

Total Pages

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Data Source

[Book] 炎症性サイトカインと骨破壊2012

Author(s)

Publisher

Data Source

KAIFU Tomonori 海部知則

KAIFU TomonoriI 海部知則

海部知則カイフトモノリ

[Book] 第1章インターロイキン「IL-18/33/36/37」サイトカイン・増殖因子キーワード事典2015