SAITO MASAO 齋藤正夫

… Alternative Names

SAITOH Masao 齋藤正夫

齊藤正夫サイトウマサオ

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Researcher Number	90345041
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 山梨大学, 大学院総合研究部, 教授 2014 – 2016: 山梨大学, 総合研究部, 教授 2014: 山梨大学, 大学院総合研究部, 教授 2013: 山梨大学, 医学工学総合研究部, 教授 2012: 山梨大学, 大学院・医学工学総合研究部, 准教授 … More 2009 – 2010: University of Yamanashi, 大学院・医学工学総合研究部, 准教授 2009: 山梨大学, 大学院・医学系研究科, 准教授 2007 – 2008: The University of Tokyo, 大学院・医学系研究科, Research Associate 2007: 大学院, 医学系研究科, 助教 2006: 東京大学, 大学院医学系研究科, 助手 2003 – 2005: 東京大学, 大学院・医学系研究科, 助手 2004: The Universty of Tokyo, Graduate School of Medicine, Assistant of Professor, 大学院医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology / Basic Section 57020:Oral pathobiological science-related / Functional basic dentistry Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Neurosurgery / Biological Sciences
Keywords	Principal Investigator EMT / TGF-β / 上皮間葉転換 / がん細胞 / Snail / ZEB1 / 浸潤 / TGF-beta / SIP1 / がん細胞分化 … More / 癌細胞分化 / CTC / 口腔癌 / がん / 上皮間葉移行 / E-cadherin / 細胞分化 / 転移 / 癌細胞 / 癌細胞の悪性化 / 循環内腫瘍細胞 / Epithelial-Mesenchymal Transtion / 転写因子 / Snai1 / シグナル伝達機構 / 分子マーカー / 悪性形質 / シグナル伝達 / 癌微小環境 / Ras / アイソフォームスイッチ / FGF-2 / 筋線維芽細胞 / 実験腫瘍学 / bHLH型転写因子 / ユビキチン / Arkadia / zinc finger型転写因子 / 翻訳制御 / IRES / Fox / c-Ski / Smad7 … More Except Principal Investigator 口腔扁平上皮癌 / 転写因子 / 浸潤 / TGF-β / 上皮間葉移行 / シスプラチン / 浸潤様式 / Smad / グリオーマ / 浸潤能 / 上皮間葉転換 / 血管新生 / シグナル伝達 / 耐性化 / 高浸潤能 / 病理組織切片 / PTK7 / 感受性 / 口腔がん / ATP7B / 脳神経疾患 / 薬剤抵抗性 / ベバシズマブ / 膠芽腫 / ZEB / angiogenesis / transcription factor / ubiquitination / anti-oncogene / oncogene / signal transduction / がんの浸潤・転移 / シグナルクロストーク / Wntシグナル / Smurf1 / 受容体 / c-myc / ユビチキン化 / BMP / ユビキチン化 / 癌抑制遺伝子 / 癌遺伝子 / マウス頭蓋内モデル / 免疫染色 / ＺＥＢ１／２ / 悪性グリオーマ / Smad7 / DDS / 乳がん / 膵臓がん / がん朝細胞 / 脳腫瘍 / 胃がん / シグナル伝逹 / 転移 / がん幹細胞 / 分子標的治療 Less

高浸潤性口腔癌におけるシスプラチン耐性化機序の解明と多面的な治療法の開発
- Principal Investigator
  
  吉澤邦夫
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  University of Yamanashi
Molecular mechanisms of differentiation of invasive cells to circulating tumor cellsPrincipal Investigator
- Principal Investigator
  
  齋藤正夫
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  University of Yamanashi
難治性口腔癌におけるPTK7発現の浸潤機構の解明と新たな臨床応用
- Principal Investigator
  
  吉澤邦夫
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  University of Yamanashi
Acquisition of susceptibility by suppressing the expression of the cisplatin efflux transporter gene (ATP7B) in oral cancer
- Principal Investigator
  
  Yoshizawa Kunio
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  University of Yamanashi
Functional analysis of cancer-associated EMT in circulating tumor cells and oral cancer cellsPrincipal Investigator
- Principal Investigator
  
  Saitoh Masao
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  University of Yamanashi
Analysis of Epithelial mesenchimal trannsion in glioma
- Principal Investigator
  
  KAWATAKI Tomoyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  University of Yamanashi
Preliminary investigation of optimal cell culture condition of circulating tumor cellsPrincipal Investigator
- Principal Investigator
  
  SAITOH Masao
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  University of Yamanashi
Identification of novel EMT molecular markers in oral cancerPrincipal Investigator
- Principal Investigator
  
  SAITOH Masao
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  University of Yamanashi
Expression of ZEBs in gliomas is associated with invasive properties and histopathological grade
- Principal Investigator
  
  KAWATAKI Tomoyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  University of Yamanashi
Investigation into mechanisms of cancer aggressiveness by epithelial cells undergoing EMTPrincipal Investigator
- Principal Investigator
  
  SAITOH Masao
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  University of Yamanashi
Roles of TGF-β signaling in cancer progressionPrincipal Investigator
- Principal Investigator
  
  SAITOH Masao
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  The University of Tokyo
Molecular analyses of TGF-β-induced Epithelial-Mesenchymal Transition in oral cancer cellsPrincipal Investigator
- Principal Investigator
  
  SAITOH Masao
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  The University of Tokyo
Establishment of New Strategies for Treatment of Cancer Using TGF-beta Signaling
- Principal Investigator
  
  MIYAZONO Kohei
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
TGF-βシグナルの翻訳制御機構と顎・口腔癌における異常の解析Principal Investigator
- Principal Investigator
  
  齋藤正夫
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  The University of Tokyo
顎・口腔領域疾患におけるTGF-βファミリー因子の作用機構の解明Principal Investigator
- Principal Investigator
  
  齋藤正夫
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokyo
Mechanisms of TGF-β signaling and its abnormalities in human cancer
- Principal Investigator
  
  MIYAZONO Kohei
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

[Book] Regulation of Signal Transduction in Human Cell Research2017
- Author(s)
  Masao Saitoh
- Publisher
  Springer社
- Data Source
  KAKENHI-PROJECT-15H05018
[Journal Article] The Snail signaling branch downstream of the TGF-β/Smad3 pathway mediates Rho activation and subsequent stress fiber formation2024
- Author(s)
  Motizuki Mitsuyoshi、Yokoyama Takashi、Saitoh Masao、Miyazawa Keiji
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 1 Pages: 105580-105580
- DOI
  10.1016/j.jbc.2023.105580
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21385, KAKENHI-PROJECT-23K24518
[Journal Article] ndole-derived compound SIS3 targets a subset of activated Smad complexes.2023
- Author(s)
  toh Y, Sawaguchi T, Fu H, Omata C, Saitoh M, Miyazawa K.
- Journal Title
  
  J Biochem.
  
  Volume: 173 Issue: 4 Pages: 283-291
- DOI
  10.1093/jb/mvac104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21385, KAKENHI-PROJECT-23K24518
[Journal Article] Smad2Δexon3 and Smad3 have distinct properties in signal transmission leading to TGF-β-induced cell motility.2023
- Author(s)
  Yokoyama T, Kuga T, Itoh Y, Otake S, Omata C, Saitoh M, Miyazawa K.
- Journal Title
  
  J Biol Chem.
  
  Volume: 299 Issue: 2 Pages: 102820-102820
- DOI
  10.1016/j.jbc.2022.102820
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21385, KAKENHI-PROJECT-23K24518
[Journal Article] Transcriptional regulation of EMT transcription factors in cancer2023
- Author(s)
  Saitoh Masao
- Journal Title
  
  Seminars in Cancer Biology
  
  Volume: 97 Pages: 21-29
- DOI
  10.1016/j.semcancer.2023.10.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24518
[Journal Article] High expression of protein tyrosine kinase 7 in oral squamous cell carcinoma: Clinicopathological correlation and prognosis relevance2022
- Author(s)
  Kimura Yujiro、Yoshizawa Kunio、Hotta‐Osada Asami、Moroi Akinori、Ishii Hiroki、Sakurai Daiju、Saitoh Masao、Oishi Naoki、Kondo Tetsuo、Ueki Koichiro
- Journal Title
  
  Clinical and Experimental Dental Research
  
  Volume: 8 Issue: 2 Pages: 506-512
- DOI
  10.1002/cre2.553
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21884, KAKENHI-PROJECT-18H02969, KAKENHI-PROJECT-21K06883, KAKENHI-PROJECT-21K10066
[Journal Article] Ets family proteins regulate the EMT transcription factors Snail and ZEB in cancer cells2022
- Author(s)
  Ichikawa Mai Koizumi、Endo Kaori、Itoh Yuka、Osada Asami Hotta、Kimura Yujiro、Ueki Koichiro、Yoshizawa Kunio、Miyazawa Keiji、Saitoh Masao
- Journal Title
  
  FEBS Open Bio
  
  Volume: - Issue: 7 Pages: 1353-1364
- DOI
  10.1002/2211-5463.13415
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21884, KAKENHI-PROJECT-18H02969, KAKENHI-PROJECT-20K18691, KAKENHI-PROJECT-21K10066, KAKENHI-PROJECT-23K24518
[Journal Article] Direct and indirect roles of GRWD1 in the inactivation of p53 in cancer.2022
- Author(s)
  2. Ichikawa MK, Saitoh M
- Journal Title
  
  J Biochem.
  
  Volume: - Issue: 6 Pages: 601-603
- DOI
  10.1093/jb/mvac010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02969, KAKENHI-PROJECT-21K10066, KAKENHI-PROJECT-23K24518
[Journal Article] Epithelial-Mesenchymal Transition by Synergy between Transforming Growth Factor-β and growth factors in Cancer Progression2022
- Author(s)
  6. Saitoh M
- Journal Title
  
  Diagnostics
  
  Volume: - Issue: 9 Pages: 2125-2125
- DOI
  10.3390/diagnostics12092125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24518
[Journal Article] Loss of intercellular bridges in the depth of invasion measurement area is a novel negative prognostic factor for oral squamous cell carcinoma: A retrospective study2022
- Author(s)
  Yoshizawa Kunio、Kimura Yujiro、Moroi Akinori、Ishii Hiroki、Sakurai Daiju、Saitoh Masao、Oishi Naoki、Kondo Tetsuo、Toyoura Masahiro、Ueki Koichiro
- Journal Title
  
  Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
  
  Volume: - Issue: 1 Pages: 84-92
- DOI
  10.1016/j.oooo.2022.02.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21884, KAKENHI-PROJECT-18H02969, KAKENHI-PROJECT-21K06883, KAKENHI-PROJECT-21K10066
[Journal Article] EHF suppresses cancer progression by inhibiting ETS1-mediated ZEB expression2021
- Author(s)
  Kaname Sakamoto, Kaori Endo, Kei Sakamoto, Kou Kayamori, Shogo Ehata, Jiro Ichikawa, Takashi Ando, Ryosuke Nakamura, Yujiro Kimura, Kunio Yoshizawa, Keisuke Masuyama, Tomoyuki Kawataki, Kunio Miyake, Hiroki Ishii, Tomonori Kawasaki, Keiji Miyazawa, and Masao Saitoh
- Journal Title
  
  oncogenesis
  
  Volume: 10 Issue: 3 Pages: 1-15
- DOI
  10.1038/s41389-021-00313-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02969, KAKENHI-PROJECT-18K09807, KAKENHI-PROJECT-20K21884, KAKENHI-PROJECT-21K06910
[Journal Article] Role of platelet C-type lectin-like receptor 2 in promoting lung metastasis in osteosarcoma2020
- Author(s)
  Jiro Ichikawa, Takashi Ando, Tomonori Kawasaki, Tomoyuki Sasaki, Toshiaki Shirai, Nagaharu Tsukiji, Yujiro Kimura, Kaoru Aoki, Keiko Hayakawa, Katsue Suzuki-Inoue, Masao Saitoh, and Hirotaka Haro
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02969
[Journal Article] Addiction of mesenchymal phenotypes on the FGF/FGFR axis in oral squamous cell carcinoma cells2019
- Author(s)
  Osada Asami Hotta、Endo Kaori、Kimura Yujiro、Sakamoto Kei、Nakamura Ryosuke、Sakamoto Kaname、Ueki Koichiro、Yoshizawa Kunio、Miyazawa Keiji、Saitoh Masao
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 11 Pages: e0217451-e0217451
- DOI
  10.1371/journal.pone.0217451
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09807, KAKENHI-PROJECT-18H02969
[Journal Article] A comparative analysis of Smad-responsive motifs identifies multiple regulatory inputs for TGF-β transcriptional activation.2019
- Author(s)
  Itoh Y, Koinuma D, Omata C, Ogami T, Motizuki M, Yaguchi SI, Itoh T, Miyake K, Tsutsumi S, Aburatani H, Saitoh M, Miyazono K, Miyazawa K.
- Journal Title
  
  J Biol Chem.
  
  Volume: 294 Issue: 42 Pages: 15466-15479
- DOI
  10.1074/jbc.ra119.009877
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06626, KAKENHI-PROJECT-18H02969, KAKENHI-PROJECT-17K19589
[Journal Article] Expression of ZEBs in gliomas is associated with invasive properties and histopathological grade2018
- Author(s)
  Keiko Suzuki, Tomoyuki Kawataki, Kaori Endo, Keiji Miyazawa, Hiroyuki Kinouchi1 Masao Saitoh
- Journal Title
  
  Oncology letter
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05018
[Journal Article] Expression of ZEBs in gliomas is associated with invasive properties and histopathological grade2018
- Author(s)
  Suzuki Keiko, Kawataki Tomoyuki, Endo Kaori, Miyazawa Keiji, Kinouchi Hiroyuki, Saitoh Masao.
- Journal Title
  
  ONCOLOGY LETTERS
  
  Volume: 16 Pages: 1758-1764
- DOI
  10.3892/ol.2018.8852
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10860
[Journal Article] The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target GPNMB2017
- Author(s)
  Yukari Okita, Minori Kimura, Rudy Xie, Chen Chen, Larina Tzu-Wei Shen, Yurika Kojima, Hiroyuki Suzuki, Masafumi Muratani, Masato Saitoh, Kentaro Semba, Carl-Henrik Heldin, and Mitsuyasu Kato
- Journal Title
  
  Science Signaling
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05018
[Journal Article] Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells2017
- Author(s)
  Sinh ND, Endo K, Miyazawa K, Saitoh M
- Journal Title
  
  Cancer Science
  
  Volume: 108 Issue: 5 Pages: 952-960
- DOI
  10.1111/cas.13214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05018
[Journal Article] Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependently on ERK1/2 activity, in breast cancer cells2017
- Author(s)
  Nguyen Duy Sinh, Kaori Endo, Keiji Miyazawa, Masao Saitoh
- Journal Title
  
  Cancer science
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05018
[Journal Article] The potential role of regulator of G-protein signaling 16 in cell motility mediated by δEF1 family proteins.2016
- Author(s)
  Hoshi Y, Endo K, Shirakihara T, Fukagawa A, Miyazawa K, Saitoh M.
- Journal Title
  
  FEBS Lett.
  
  Volume: 590 Issue: 2 Pages: 270-278
- DOI
  10.1002/1873-3468.12042
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05018
[Journal Article] Maid is a negative regulator of transforming growth factor-β-induced cell migration.2015
- Author(s)
  Motizuki M, Saitoh M, Miyazawa K.
- Journal Title
  
  J Biochem.
  
  Volume: 158 Issue: 5 Pages: 435-444
- DOI
  10.1093/jb/mvv054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05018
[Journal Article] STAT3 integrates cooperative Ras and TGF-β signals that induce Snail expression2015
- Author(s)
  Masao Saitoh, Kaori Endo, Satoshi Furuya, Munetaka Minami, Akira Fukasawa, Takeshi Imamura, Keiji Miyazawa
- Journal Title
  
  Oncogene
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390419
[Journal Article] The epithelial-mesenchymal transition is regulated at the post-transcriptional levels by TGF-β signaling during tumor progression2015
- Author(s)
  Masao Saitoh
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中 Issue: 5 Pages: 481-488
- DOI
  10.1111/cas.12630
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390419
[Journal Article] Oligodendrocyte transcription factor 1 (Olig1) is a Smad cofactor involved in cell motility induced by transforming growth factor-β2013
- Author(s)
  Motizuki M, Isogaya K, Miyake K, Ikushima H, Kubota T, Miyazono K, Saitoh M, Miyazawa K.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288 Issue: 26 Pages: 18911-18922
- DOI
  10.1074/jbc.m113.480996
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-24390419, KAKENHI-PROJECT-25860852
[Journal Article] Identification of integrin α3 as a molecular marker of cells undergoing epithelial-mesenchymal transition and of cancer cells with aggressive phenotypes.2013
- Author(s)
  Shirakihara T, Kawasaki T, Fukagawa A, Semba K, Sakai R, Miyazono K, Miyazawa K, Saitoh M.
- Journal Title
  
  Cancer Science
  
  Volume: 104 Issue: 9 Pages: 1189-1197
- DOI
  10.1111/cas.12220
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-23300353, KAKENHI-PROJECT-24390419, KAKENHI-PROJECT-25830096
[Journal Article] Basolateral BMP signaling in polarized epithelial cells2013
- Author(s)
  Saitoh M, Shirakihara T, Fukasawa A, Horiguchi K, Sakamoto K, Sugiya H, Beppu H, Fujita Y, Morita I, Miyazono K, Miyazawa K.
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 5 Pages: 1-10
- DOI
  10.1371/journal.pone.0062659
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-22390059, KAKENHI-PROJECT-24390419, KAKENHI-PROJECT-24580433
[Journal Article] Basolateral BMP signaling in polarized epithelial cells2013
- Author(s)
  M Saitoh, et al
- Journal Title
  
  PLOSONE
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390419
[Journal Article] TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition.2011
- Author(s)
  Shirakihara T, Horiguchi K, Miyazawa K, Ehata S, Shibata T, Morita I, Miyazono K, Saitoh M.
- Journal Title
  
  EMBO J. 30
  
  Pages: 783-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] Transforming Grawth Factor-βsignaling and Epithelial Mesenchymal Transition2011
- Author(s)
  Saitoh.M
- Journal Title
  
  J. Oral Biosci.
  
  Volume: 53 Pages: 57-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] Miyazono K, Miyazawa K Identification of a phosphorylation site in c-Ski as serine 515.2010
- Author(s)
  Nagata M, Nagata S, Yuki K, Isogaya K, Saitoh M
- Journal Title
  
  J.Biochem. 148(4)
  
  Pages: 423-427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] RB1CC1 activates RB1 pathway and inhibits proliferation and cologenic survival in human cancer.2010
- Author(s)
  Chano T, Ikebuchi K, Ochi Y, Tameno H, Tomita Y, Jin Y, Inaji H, Ishitobi M, Teramoto K, Nishimura I, Minami K, Inoue H, Isono T, Saitoh M, Shimada T, Hisa Y, Okabe H.
- Journal Title
  
  PLoS One. 5
  
  Pages: 11404-11404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] Arkadia complexes with clathrin adaptor AP2 and regulates EGF signalling.2010
- Author(s)
  Mizutani A, Saitoh M, Imamura T, Miyazawa K, Miyazono K.
- Journal Title
  
  J.Biochem. 148
  
  Pages: 733-741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] RB1CC1 together with RB1 and p53 predicts long-term survival in japanese breast cancer patients.2010
- Author(s)
  Chano T, Ikebuchi K, Tomita Y, Jin Y, Inaji H, Ishitobi M, Teramoto K, Ochi Y, Tameno H, Nishimura I, Minami K, Inoue H, Isono T, Saitoh M, Shimada T, Hisa Y, Okabe H.
- Journal Title
  
  PLoS One. 5
  
  Pages: 15737-15737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] Forkhead box F1 regulates tumor-promoting properties of cancer-associated fibroblasts in lung cancer2010
- Author(s)
  Saito, R.A., et al.
- Journal Title
  
  Cancer Research 70
  
  Pages: 2644-2654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Thyroid transcription factor-1 inhibits transforming growth factor-β-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells2009
- Author(s)
  Saito, R.A., et al.
- Journal Title
  
  Cancer Research 69
  
  Pages: 2783-2791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Regulation of the stability of cell surface E-cadherin by the proteasome2009
- Author(s)
  Saitoh, M., et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun 381
  
  Pages: 560-565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Regulation of the stability of cell surface E-cadherin by the proteasome.2009
- Author(s)
  Saitoh M, Shirakihara T, Miyazono K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 381
  
  Pages: 560-565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] Thyroid transcription factor-1 inhibits transforming growth factor- β- mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells.2009
- Author(s)
  Saito, R.A., Watabe, T., Horiguchi, K., Kohyama, T., Saitoh, M., Nagase, T., Miyazono, K.
- Journal Title
  
  Cancer Res. 69(7)
  
  Pages: 2783-2791
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Role of Ras signaling in the induction of snail by TGF-b.2009
- Author(s)
  Horiguchi K, Shirakihara T, Nakano A, Imamura T, Miyazono K, Saitoh M.
- Journal Title
  
  J.Biol.Chem 284
  
  Pages: 245-253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] Dp63 -dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma with epithelial-to-mesenchymal transition.2009
- Author(s)
  Higashikawa K, Yoneda1S, Tobiume K, Saitoh M, Taki M, Mitani Y, Shigeishi H, Ono S, Kamata N.
- Journal Title
  
  Int J.Cancer 124
  
  Pages: 2837-2844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] Thyroid transcription factor-1 inhibits transforming growth factor-beta-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells.2009
- Author(s)
  Saito RA, Watabe T, Horiguchi K, Kohyama T, Saitoh M, Nagase T, Miyazono K.
- Journal Title
  
  Cancer Res. 69
  
  Pages: 2783-2791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] TTF-1 inhibits TGF-β-mediated EMT in lung adenocarcinoma cells2009
- Author(s)
  Saito RA., etal
- Journal Title
  
  Cancer Research 69
  
  Pages: 2783-2791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] Pin1 downregulates TGF-beta signaling by inducing degradation of Smad proteins.2009
- Author(s)
  Nakano A, Koinuma D, Miyazawa K, Uchida T, Saitoh M, Kawabata M, Hanai JI, Akiyama H, Abe M, Miyazono K, Matsumoto T, Imamura T.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 6109-6115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] Role of Ras signaling in the induction of snail by transforming growth factor-β.2009
- Author(s)
  Horiguchi, K., Shirakihara, T., Nakano, A., Imamura, T., Miyazono, K., Saitoh, M.
- Journal Title
  
  J. Biol. Chem. 284(1)
  
  Pages: 245-253
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Regulation of the stability of cell surface E-cadherin by the proteasome2009
- Author(s)
  Saitoh M., etal
- Journal Title
  
  Biochemical and Biophysical Research Cmmunication 381
  
  Pages: 560-565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells.2008
- Author(s)
  Fukunaga E, Inoue Y, Komiya S, Horiguchi K, Goto K, Saitoh M, Miyazawa K, Koinuma D, Hanyu A, Imamura T.
- Journal Title
  
  J.Biol.Chem 283
  
  Pages: 35660-35667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390476
[Journal Article] Arkadia induces degradation of SnoN and c-Ski to enhance TGF-βsignaling.2007
- Author(s)
  Nagano, Y., Mavrakis, K.J., Lee, K.L., Fujii, T., Koinuma, D., Sase, H., Yuki, K., Isogaya, K., Saitoh, M., Imamura, T., Episkopou, V., Miyazono, K., Miyazawa, K.
- Journal Title
  
  J. Biol. Chem. 282(28)
  
  Pages: 20492-20501
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Transforming growth factor-n promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC12007
- Author(s)
  Ehata S, Hanyu A, Hayashi M, Aburatani H, Kato Y, Fujime M, Saitoh M, Miyazawa K, Imamura T, Miyazono K
- Journal Title
  
  Can Res. 67
  
  Pages: 9694-9703
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390496
[Journal Article] Differential regulation of epithelial and mesenchymal markers byδEF1 proteins in epithelial mesenchymal transition induced by TGF-β.2007
- Author(s)
  Shirakihara, T., Saitoh, M., Miyazono K.
- Journal Title
  
  Mol. Biol. Cell 18(9)
  
  Pages: 3533-3544
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Transforming growth factor-βpromotes survival of mammary carcinoma cells through induction of anti-apoptotic transcription factor DEC1.2007
- Author(s)
  Ehata, S., Hanyu, A., Hayashi, M., Aburatani, H., Kato, Y., Fujime, M., Saitoh, M., Miyazawa, K., Imamura, T., Miyazono, K.
- Journal Title
  
  Cancer Res. 67(20)
  
  Pages: 9694-9703
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Differential Regulation of Epithelial and Mesenchymal Markers by δEF1 Proteins in Epithelial Mesenchymal Transition Induced by TGF-β2007
- Author(s)
  Shirahirakihara T, Saitoh M, Miyazono K
- Journal Title
  
  Mol. Biol. Cell. 18
  
  Pages: 3533-3544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390496
[Journal Article] Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-β signaling2007
- Author(s)
  Nagano Y, Mavrakis KJ, Lee KL, Fujii T, Koinuma D, Sase H, Yuki K, Isogaya K, Saitoh M, Imamura T, Episkopou V, Miyazono K, Miyazawa K
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 20492-20501
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390496
[Journal Article] Execution of BMP-4- induced apoptosis by p53-dependent ER dysfunction in myeloma and B-cell hybridoma cells.2006
- Author(s)
  Fukuda, N., Saitoh, M., Kobayashi, N., Miyazono, K.
- Journal Title
  
  Oncogene 25(25)
  
  Pages: 3509-3517
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Nuclear and cytoplasmic c-Ski differentially modulate cellular functions.2006
- Author(s)
  Nagata, M., Goto, K., Ehata, S., Kobayashi, N., Saitoh, M., Miyoshi, H., Imamura, T., Miyazawa, K., Miyazono, K.
- Journal Title
  
  Genes Cells 11(11)
  
  Pages: 1267-1280
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] The ALK-5 Inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-β.2005
- Author(s)
  Tojo, M., Hamashima, Y., Hanyu, A., Kajimoto, T., Saitoh, M., Miyazono, K., Node, M., Imamura, T.
- Journal Title
  
  Cancer Sci. 96(11)
  
  Pages: 791-800
- NAID
  10017091727
- Data Source
  KAKENHI-PROJECT-17016011
[Presentation] グリオーマにおけるZEB1/2の発現と浸潤能および病理学的悪性度との相関2019
- Author(s)
  川瀧智之、鈴木景子、齋藤正夫、宮澤恵二、木内博之
- Organizer
  第19回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-17K10860
[Presentation] A novel point mutation of EHF functions as an EMT promoter via regulating ETS-ZEB pathway2019
- Author(s)
  Kaname Sakamoto, Keiji Miyazawa, and Masao Saitoh
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18H02969
[Presentation] 口腔扁平上皮癌におけるFGFRc isoformの機能解析2018
- Author(s)
  堀田麻実、中村亮介、吉澤邦夫、齋藤正夫
- Organizer
  第55回日本口腔組織培養学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09807
[Presentation] グリオーマにおけるZEB1/2の発現と浸潤能および病理学的悪性度との相関2018
- Author(s)
  川瀧智之、鈴木景子、齋藤正夫、宮澤恵二、木内博之
- Organizer
  第19回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-17K10860
[Presentation] 上皮間葉転換転写因子とグリオーマ浸潤能への関与2017
- Author(s)
  鈴木景子、川瀧智之、宮澤恵二、齋藤正夫、木内博之
- Organizer
  第18回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-17K10860
[Presentation] Expression of ZEBs in gliomas is associated with invasive properties and histopathological grade2017
- Author(s)
  Masao Saitoh
- Organizer
  International EMT meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05018
[Presentation] Stat3 integrates cooperative Ras and TGF-b signals that induce Snail expression2015
- Author(s)
  齋藤正夫
- Organizer
  日本癌学会総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H05018
[Presentation] Stat3 integrates cooperative Ras and TGF-b signals that induce Snail expression2015
- Author(s)
  Masao Saitoh
- Organizer
  the 7Th EMT meeting
- Place of Presentation
  The Pullman Albert Park Melbourne(オーストラリア・メルボルン）
- Year and Date
  2015-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05018
[Presentation] Identification of integrin α3 as a molecular marker of cells undergoing epithelial-mesenchymal transition and of cancer cells with aggressive phenotypes.2013
- Author(s)
  Masao Saitoh
- Organizer
  6th EMT meeting
- Place of Presentation
  Hotel Melia (Alicante, Spain)
- Data Source
  KAKENHI-PROJECT-24390419
[Presentation] FGF-2 accelerates TGF-beta-induced EMT2013
- Author(s)
  Masao Saitoh
- Organizer
  AACR
- Place of Presentation
  Omni SanDiego (アメリカ)
- Year and Date
  2013-01-21
- Data Source
  KAKENHI-PROJECT-24390419
[Presentation] Identification of integrin α3 as a molecular marker of cells undergoing EMT and of cancer cells with aggressive phenotypes2013
- Author(s)
  Masao Saitoh
- Organizer
  FASEB meeting
- Place of Presentation
  The Steamboat Grand Resort (Steamboat SpringsSteamboat, USA)
- Data Source
  KAKENHI-PROJECT-24390419
[Presentation] role of TGF-b superfamily signals in EMT and epithelial cell polarity2013
- Author(s)
  Masao Saitoh
- Organizer
  第８６回生化学会総会
- Place of Presentation
  横浜コンチネンタルホテル（神奈川県横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-24390419
[Presentation] Identification of integrin α3 as a molecular marker of cells undergoing epithelial-mesenchymal transition and of cancer cells with aggressive phenotypes.2013
- Author(s)
  齋藤正夫
- Organizer
  第５５回歯科基礎医学会総会
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-24390419
[Presentation] Roles of TGF-b superfamily signals in EMT and cancer progression2012
- Author(s)
  Masao Saitoh
- Organizer
  日本癌学会総会
- Place of Presentation
  札幌文化会館(北海道)(招待講演)
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24390419
[Presentation] TGF-b誘導性EMTの分子機構2012
- Author(s)
  Masao Saitoh
- Organizer
  歯科基礎医学会総会
- Place of Presentation
  奥羽大学(福島県)
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-24390419
[Presentation] Role of BMP signaling in TGF-b mediated EMT2012
- Author(s)
  Masao Saitoh
- Organizer
  TGF-beta meeting
- Place of Presentation
  Leiden大学(オランダ)
- Year and Date
  2012-08-30
- Data Source
  KAKENHI-PROJECT-24390419
[Presentation] TGF-βswitches isoform of FGF receptors and regulates EMT of cancer-associated epithelial cells2011
- Author(s)
  Masao Saitoh
- Organizer
  Keystone meeting
- Place of Presentation
  Bancouver, Canada
- Year and Date
  2011-01-23
- Data Source
  KAKENHI-PROJECT-20390476
[Presentation] TGF-b signaling & EMT in cancer progression2010
- Author(s)
  齋藤正夫
- Organizer
  日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20390476
[Presentation] TGF-b signaling and EMT in cancer progression2010
- Author(s)
  齋藤正夫
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20390476
[Presentation] FGF-2 accelerates TGF-β-induced EMT and promotes invasion of cancer cells2010
- Author(s)
  Masao Saitoh
- Organizer
  AACR
- Place of Presentation
  Washington, USA
- Year and Date
  2010-03-01
- Data Source
  KAKENHI-PROJECT-20390476
[Presentation] 癌細胞浸潤過程におけるEMTの役割2009
- Author(s)
  齋藤正夫
- Organizer
  歯科基礎医学会総会
- Place of Presentation
  新潟
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PROJECT-20390476
[Presentation] FGF-2 accelerates TGF-β-induced EMT and promotes invasion of cancer cells2009
- Author(s)
  齋藤正夫
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20390476
[Presentation] molecular mechanism of TGF-b-induced EMT2009
- Author(s)
  齋藤正夫
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20390476
[Presentation] Molecular mechanism of TGF-β-induced EMT2009
- Author(s)
  齋藤正夫
- Organizer
  日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20390476
[Presentation] FGF-2 accelerate TGF-b-induced EMT and promotes invasion of cancer cells2009
- Author(s)
  Masao Saitoh, Takuya Shirakihara, Kana Horiguchi, Kohei Miyazono
- Organizer
  第32回日本分子生物学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20390476
[Presentation] Differential Regulation of Epithelial and Mesenchymal Markers by dEF1 Proteins in Epithelial Mesenchymal Transition Induced by TGF-b2007
- Author(s)
  Shirakihara T., Anna Mizutani, Masao Saitoh, Kohei Miyazono
- Organizer
  Epithelial Mesenchymal Transition Conference
- Place of Presentation
  Krakow, Poland
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390496
[Presentation] δEF1associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells
- Author(s)
  Masao Saitoh, Akihiko Fukagawa, Hiroki Ishii, Keiji Miyazawa
- Organizer
  第７３回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24390419
[Presentation] Roles of STAT3 in Snail induction by the synergism between Ras and TGF-β
- Author(s)
  Masao Saitoh, Satoshi Furuya, Keiji Miyazawa
- Organizer
  TGF-beta meeting
- Place of Presentation
  筑波大学（茨城県・つくば市）
- Year and Date
  2015-01-11 – 2015-01-13
- Data Source
  KAKENHI-PROJECT-24390419
[]

1. MIYAZAWA Keiji (40209896)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. Yoshizawa Kunio (60452108)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. SAKAMOTO Kei

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MIYAZONO Kohei (90209908)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
5. IMAMURA Takeshi (70264421)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. WATABE Tetsuro (00334235)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. KAWATAKI Tomoyuki (20303406)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. 上木耕一郎 (40313663)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
9. ISHII Hiroki

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. FURUYA Satoshi

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. MAEDA Shingo (60353463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KANO Mitsunobu (80447383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. KOINUMA Daizo (80375071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. EHATA Shogo (90506726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 加藤光保 (20194855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 井上博文 (70321635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 堀田麻実 (00754607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 諸井明徳 (60645141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ENDO Kaori

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. HOSHI Yuta

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. FUKAGAWA Akihiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. KAWASAKI Tomonori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SAKAMOTO Kaname

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NAKAMURA Ryosuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. HOTTA Asami

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 伊藤友香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAITO MASAO 齋藤 正夫

SAITOH Masao 齋藤 正夫

齊藤 正夫 サイトウ マサオ

Research Projects

Research Products

Co-Researchers

高浸潤性口腔癌におけるシスプラチン耐性化機序の解明と多面的な治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of differentiation of invasive cells to circulating tumor cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

難治性口腔癌におけるPTK7発現の浸潤機構の解明と新たな臨床応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Acquisition of susceptibility by suppressing the expression of the cisplatin efflux transporter gene (ATP7B) in oral cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of cancer-associated EMT in circulating tumor cells and oral cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of Epithelial mesenchimal trannsion in glioma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Preliminary investigation of optimal cell culture condition of circulating tumor cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of novel EMT molecular markers in oral cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression of ZEBs in gliomas is associated with invasive properties and histopathological grade

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation into mechanisms of cancer aggressiveness by epithelial cells undergoing EMTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of TGF-β signaling in cancer progressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analyses of TGF-β-induced Epithelial-Mesenchymal Transition in oral cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of New Strategies for Treatment of Cancer Using TGF-beta Signaling

Principal Investigator

SAITO MASAO 齋藤正夫

SAITOH Masao 齋藤正夫

齊藤正夫サイトウマサオ