Sato Toshiya 佐藤俊哉

… Alternative Names

SATOU Toshiya 佐藤俊哉

SATO Toshiya 佐藤俊哉

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Researcher Number	90359703
External Links
Affiliation (Current)	2025: 北里大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 北里大学, 医学部, 教授 2019 – 2022: 北里大学, 医学部, 教授 2014 – 2016: 北里大学, 医学部, 教授 2015: 北里大学, 医学部, 助教 2010 – 2013: 新潟大学, 脳研究所, 助教 2003 – 2006: 新潟大学, 脳研究所, 助手
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related / Basic Section 51030:Pathophysiologic neuroscience-related Except Principal Investigator Neurology / Morphological basic dentistry / Laboratory animal science / Laboratory animal science / Nerve anatomy/Neuropathology
Keywords	Principal Investigator 疾患モデル / TDP-43 / 筋萎縮性側索硬化症 / ALS / 脳神経疾患 / 質量分析 / 翻訳後修飾 / 発生・分化 / 初期胚発生 Except Principal Investigator 神経病態 … More / 脳小血管 / keratin 5 promoter / intraepithelial stoma / stellate reticulum / enamel organ / overexpression / transgenic mice / perlecan / heparan sulfate proteoglycan / ケラチン5プロモータ / ヘバラン硫酸プロテオグリカン / ケラチン5プロモーター / 上皮内基質 / 星状網 / 歯胚エナメル器 / 過剰発現 / トランスジェニックマウス / パールカン / ヘパラン硫酸プロテオグリカン / cryopreservation / ovary / line preservation / mouse / 凍結保存 / 卵巣 / 系統保存 / マウス / 運動機能調節 / ニホンザル / 生殖工学的技術 / 時期特異的ノックダウン / 遺伝子改変マウス / パーキンソン病モデル動物 / 発達期 / 電気生理学的性質 / 時期特異的発現抑制 / 運動調節 / 運動学習 / 学習記憶 / 電気生理学的解析 / 可逆的発現制御マウス / ドーパミン受容体 / 神経活動 / テトラサイクリン制御システム / 遺伝子操作マウス / パーキンソン病 / 大脳基底核回路 / 運動制御 / D2ドーパミン受容体 / D1ドーパミン受容体 / 神経病帯 / 脳循環 / 脳血管 / 筋萎縮性側索硬化症 / サイトカイ / 炎症 / モデルマウス / 微小循環 / TGF-β / 血管性認知症 / 周皮細胞 / 平滑筋細胞 / HTRA1 / 血液脳関門 / CARASIL / Cajal小体 / 核内小体 / SMN / U12 snRNA / TDP-43 / GEM / ALS / 動物モデル / DNAチップ / てんかん外科 / 分子病理 / 皮質形成異常 / 難治てんかん Less

TDP-43 GaroS2領域のリン酸化による機能変化とALS病態との関連解明Principal Investigator
- Principal Investigator
  
  佐藤俊哉
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kitasato University
Exploring primary amino acid structures and post-translational modifications that regulate nuclear import of TDP-43Principal Investigator
- Principal Investigator
  
  Sato Toshiya
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kitasato University
Elucidation of motor control mechanism by D1 / D2 dopamine receptor conditionally expressing mice
- Principal Investigator
  
  SASAOKA Toshikuni
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Niigata University
Autoreguation of TDP-43 in ALS
- Principal Investigator
  
  Nishizawa Masatoyo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Approach to cerebral small vessel disease: lesson from CARASIL.
- Principal Investigator
  
  Onodera Osamu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Establishment of TDP-43 C-terminal deficient mice using zinc finger nuclease and application to the model for amyotrophic lateral sclerosisPrincipal Investigator
- Principal Investigator
  
  SATO TOSHIYA
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kitasato University
  Niigata University
Molecular pathogenesis of ALS: approach from TDP-43 function.
- Principal Investigator
  
  NISHIZAWA Masatoyo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Molecular pathogenesis of cerebral small vessel disease.
- Principal Investigator
  
  ONODERA Osamu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Analysis of TDP-43 functions and modeling for ALS using conditional knockout micePrincipal Investigator
- Principal Investigator
  
  SATO Toshiya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Establish system of mouse ovary cryopreservation as the novel method of line preservation.
- Principal Investigator
  
  YOKOYAMA Minesuke
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Niigata University
The role of basement membrane type heparan sulfate proteoglycan, perlecan, in epithelial morphogenesis -transgenic mice overexpressing perlecan in the epithelial cells-
- Principal Investigator
  
  IDA Hiroko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Niigata University
難治てんかん原性病巣としての「皮質形成異常」の分子病理学的診断基準の確立
- Principal Investigator
  
  高橋均
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University

All 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2006 2005 Other

All Journal Article Presentation

[Journal Article] Importance of the Q/N-rich segment for protein stability and activity of endogenous mouse TDP-432022
- Author(s)
  Sato T, Oda K, Sakai S, Kato R, Yamamori S, Itakura M, Kodera Y, Nishizawa M, Sasaoka T, Onodera O, Yokoyama M
- Journal Title
  
  Scientific Reports,
  
  Volume: 12 Issue: 1 Pages: 14923-14923
- DOI
  10.1038/s41598-022-19153-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19K07848
[Journal Article] Importance of the Q/N-rich Segment for Protein Stability and Activity of Endogenous Mouse TDP-432021
- Author(s)
  Toshiya Sato
- Journal Title
  
  Research Square
  
  Volume: －
- DOI
  10.21203/rs.3.rs-1113360/v1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07848, KAKENHI-PROJECT-16H06276
[Journal Article] Characteristic features and progression of abnormalities on MRI for CARASIL2015
- Author(s)
  Hiroaki Nozaki, Yumi Sekine, Toshio Fukutake, Yoshinori Nishimoto, Yutaka Shimoe, Akiko Shirata, Sohei Yanagawa, Mikio Hirayama, Masato Tamura, Masatoyo Nishizawa, and Osamu Onodera
- Journal Title
  
  Neurology
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293200
[Journal Article] Expression pattern of immediate early genes in the cerebellum of D1R KO, D2R KO, and wild type mice under vestibular-controlled activity2015
- Author(s)
  Nakamura T, Sato A, Kitsukawa T, Sasaoka T, Yamamori T.
- Journal Title
  
  Front Cell Dev Biol.
  
  Volume: 3 Pages: 1-15
- DOI
  10.3389/fcell.2015.00038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25430009, KAKENHI-PROJECT-26290029, KAKENHI-ORGANIZER-22123001
[Journal Article] 統合失調症モデルマウスの行動解析方法の試み2015
- Author(s)
  笹岡俊邦,佐藤朝子,中村徹,大久保直,佐藤俊哉,藤澤信義,前田宜俊,小田佳奈子,酒井清子,神保幸弘,馬川恵梨子,木津川尚史,籾山俊彦,山森哲雄
- Journal Title
  
  日本生物学的精神医学会誌
  
  Volume: 26 Pages: 87-94
- NAID
  130005395590
- Open Access
- Data Source
  KAKENHI-PROJECT-26290029
[Journal Article] Dopamine D1 receptor-mediated transmission maintains information flow through the cortico-striato-entopeduncular direct pathway to release movements.2015
- Author(s)
  Chiken S, Sato A, Ohta C, Kurokawa M, Arai S, Maeshima J, Sunayama-Morita T, Sasaoka T, Nambu A
- Journal Title
  
  Cerebral Cortex
  
  Volume: 25 Issue: 12 Pages: 4885-4897
- DOI
  10.1093/cercor/bhv209
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PROJECT-25430021, KAKENHI-PROJECT-25440173, KAKENHI-PROJECT-26290029, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05873, KAKENHI-PROJECT-26250009
[Journal Article] TDP-43の生理的機能とALS病態における意義2015
- Author(s)
  佐藤俊哉
- Journal Title
  
  北里医学
  
  Volume: 45 Pages: 79-85
- NAID
  40020708358
- Data Source
  KAKENHI-PROJECT-25461271
[Journal Article] Lack of dopaminergic inputs elongates the primary cilia of striatal neurons.2014
- Author(s)
  2.Miyoshi K, Kasahara K, Murakami S, Takeshima M, Kumamoto N, Sato A, Miyazaki I, Matsuzaki S, Sasaoka T, Katayama T, Asanuma M.
- Journal Title
  
  PLoS One
  
  Volume: 9(5) Issue: 5 Pages: e97918-e97918
- DOI
  10.1371/journal.pone.0097918
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591705, KAKENHI-PROJECT-24591681, KAKENHI-PROJECT-24659431, KAKENHI-PROJECT-25461279, KAKENHI-PROJECT-26290029
[Journal Article] Direct motor impairments of dopamine D1 and D2 receptor knockout mice revealed by three types of motor behavior2014
- Author(s)
  Nakamura T, Sato A, Kitsukawa T, Momiyama T, Yamamori T & Sasaoka T
- Journal Title
  
  Frontiers in Inregrative Neuroscience
  
  Volume: 8 Pages: 1-11
- DOI
  10.3389/fnint.2014.00056
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500464, KAKENHI-PROJECT-25430009, KAKENHI-PROJECT-26290029
[Journal Article] GABAergic synaptic transmission onto striatal cholinergic interneurons in dopamine D2 receptor knock-out mice.2014
- Author(s)
  Sato A, Sasaoka T, Nishijo T, Momiyama T.
- Journal Title
  
  Neuroscience
  
  Volume: 263 Pages: 138-147
- DOI
  10.1016/j.neuroscience.2014.01.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500464, KAKENHI-PROJECT-26290029
[Journal Article] Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.2013
- Author(s)
  Ishihara T, Ariizumi Y, Shiga A, et al ;
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 22 Issue: 20 Pages: 4136-4147
- DOI
  10.1093/hmg/ddt262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07914, KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-24790875, KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065
[Journal Article] FTLD/ALS as TDP-43proteinopathies2010
- Author(s)
  Ishihara T, Ariizumi Y, Shiga A,Yokoseki A, Sato T, Toyoshima Y,Kakita A,Takahashi H, Nishizawa M,Onodera O
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 50(11) Pages: 1022-4
- NAID
  130004504601
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] A case of amyotrophiclateral sclerosis/frontotemporallobar degeneration with apraxia ofeyelid opening2010
- Author(s)
  Yajima R, Kasuga K, Sato T, Ikeuchi T,Nishizawa M
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 50(9) Pages: 645-50
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] 開眼失行を呈した筋萎縮性側索硬化症1前頭側頭葉変性症の1例2010
- Author(s)
  矢島隆二, 春日健作, 佐藤朋江, 池内健, 西澤正豊
- Journal Title
  
  臨床神経学
  
  Volume: 50 Pages: 645-650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] Animal models for polyglutamine diseases- Relationship between morphological changes and neuronal dysfunction.2006
- Author(s)
  Toshiya Sato
- Journal Title
  
  J.Clin.Exp.Med. 219-4
  
  Pages: 253-256
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300133
[Journal Article] ポリグルタミン病の動物モデル-形態変化と機能障害の関連2006
- Author(s)
  佐藤俊哉
- Journal Title
  
  医学のあゆみ 219・4
  
  Pages: 253-256
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300133
[Journal Article] p53 prevents maturation of T cell development to the immature CD4-CD8+ stage in Bcl11b-/- mice.2005
- Author(s)
  Okazuka, K., Wakabayashi, Y., Kashihara, M., Inoue, J., Sato, T., Yokoyama, M., Aizawa, S., Aizawa, Y., Mishima, Y., Kominami, R.
- Journal Title
  
  Biochem.Biophys.Res.Commun., 328
  
  Pages: 545-549
- Data Source
  KAKENHI-PROJECT-17300133
[Presentation] ALS原因遺伝子産物TDP-43の解析2022
- Author(s)
  佐藤俊哉
- Organizer
  2021年度脳研究所共同利用共同研究（笹岡班）合同セミナー
- Data Source
  KAKENHI-PROJECT-19K07848
[Presentation] 筋萎縮性側索硬化症モデルの作成と解析2020
- Author(s)
  佐藤俊哉
- Organizer
  2020年度脳研究所共同利用共同研究（笹岡班）合同セミナー
- Data Source
  KAKENHI-PROJECT-19K07848
[Presentation] TDP-43細胞内局在スイッチ制御による筋萎縮性側索硬化症モデルの作成2019
- Author(s)
  佐藤俊哉
- Organizer
  2019年度脳研究所共同利用共同研究（笹岡班）合同セミナー
- Data Source
  KAKENHI-PROJECT-19K07848
[Presentation] Dopamine D1 receptor-mediated transmission maintains information flow through the cortico-striato-entopeduncular direct pathway to release movements2017
- Author(s)
  笹岡俊邦，佐藤朝子，知見聡美，大久保直，前島純，新井慧，砂山智子，小田佳奈子，酒井清子，前田宜俊，神保幸弘，中尾聡宏，佐藤俊哉，藤澤信義，南部篤
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  静岡県浜松市浜松アクトシティコングレスセンター
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] Ｄ１/Ｄ２ドーパミン受容体コンディショナル発現マウスによる運動制御機構の解明2017
- Author(s)
  笹岡俊邦, 佐藤朝子, 知見聡美, 大久保直, 阿部学, 川村名子, 中尾聡宏, 小田佳奈子, 酒井清子, 前田宜俊, 神保幸弘, 佐藤俊哉, 藤澤信義, 崎村建司, 南部篤
- Organizer
  平成28年度先端モデル動物支援プラットフォーム成果発表会
- Place of Presentation
  滋賀県大津市琵琶湖ホテル
- Year and Date
  2017-02-06
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] Ｄ１ドーパミン受容体を介する神経伝達は運動情報の伝達と運動の発現に不可欠である2016
- Author(s)
  笹岡俊邦, 佐藤朝子, 知見聡美, 大久保直, 前島純, 新井慧, 砂山智子, 小田佳奈子, 酒井清子, 前田宜俊, 神保幸弘, 馬川恵梨子,佐藤俊哉, 藤澤信義, 横山峯介, 南部篤
- Organizer
  第57回新潟生化学懇話会
- Place of Presentation
  新潟県新潟市新潟大学医歯学総合病院新潟医療人育成センター
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] ドーパミン受容体サブタイプD1R、D2R 遺伝子欠損マウスは３種類の行動解析課題でそれぞれ異なる表現型を示す2016
- Author(s)
  )中村徹,佐藤朝子,木津川尚史,籾山俊彦,山森哲雄, 笹岡俊邦
- Organizer
  第57回新潟生化学懇話会
- Place of Presentation
  新潟県新潟市新潟大学医歯学総合病院新潟医療人育成センター
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] Ｄ１ドーパミン受容体を介する神経伝達は運動情報の伝達と運動の発現に不可欠である2016
- Author(s)
  笹岡俊邦, 佐藤朝子, 知見聡美, 大久保直, 前島純, 新井慧, 砂山智子, 小田佳奈子, 酒井清子, 前田宜俊, 神保幸弘, 中尾聡宏, 佐藤俊哉, 藤澤信義, 横山峯介, 南部篤
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] Depletion of TDP-43 induces mitochondrial fragmentation.2015
- Author(s)
  Gaku Ito, Akihide Koyama, Atsushi Shiga, Sachiko Hirokawa, Yasuko Toyoshima, Akiyoshi Kakita, Masatoyo Nihizawa, Osamu Onodera.
- Organizer
  Neuroscience 2015
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] 初期胚の体外培養がマウスの産仔数および個体の臓器重量に及ぼす影響2015
- Author(s)
  小田佳奈子、佐藤俊哉、前田宜俊、酒井清子、神保幸弘、藤澤信義、横山峯介、笹岡俊邦
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都テルサ (京都府京都市)
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] D1ドーパミン受容体を介するシグナルによる運動量の維持2015
- Author(s)
  笹岡俊邦、佐藤朝子、知見聡美、大久保直、前島純、新井慧、砂山-森田智子、小田佳奈子、酒井清子、前田宜俊、神保幸弘、馬川恵梨子、佐藤俊哉、藤澤信義、横山峯介、南部篤
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド (兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] D１ドーパミン受容体の発現の減少はマウスの運動量の低下を誘導する2015
- Author(s)
  笹岡俊邦、佐藤朝子、大久保直、藤澤信義、佐藤俊哉、小田佳奈子、前田宜俊、田中稔、山本美丘、酒井清子、神保幸弘、千葉さおり、馬川恵梨子、横山峯介
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都テルサ (京都府京都市)
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] Primary cilia of striatal neurons are elongated by absence of dopaminergic inputs.2015
- Author(s)
  Miyoshi K, Kasahara K, Miyazaki I, Matsuzaki S, Sato A, Sasaoka T, Asanuma M, Katayama T.
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際展示場 (兵庫県神戸市)
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] ドーパミンD1受容体を介する神経伝達は大脳基底核の直接路の情報伝達と運動の発現に不可欠である2015
- Author(s)
  笹岡俊邦, 佐藤朝子, 知見聡美, 大久保直, 前島純, 新井慧, 砂山智子, 小田佳奈子, 酒井清子, 前田宜俊, 神保幸弘, 馬川恵梨子, 佐藤俊哉, 藤澤信義, 横山峯介, 南部篤
- Organizer
  第32回生殖工学研究会
- Place of Presentation
  実験動物中央研究所 (神奈川県川崎市)
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] Characteristic brain MRI features in HTRA1 mutation heterozygotes.2015
- Author(s)
  Masahiro Uemura, Hiroaki Nozaki, Yumi Sekine, Ikuko Mizuta, Tomoko Noda, Kazuhide Miyazaki, Muichi Kaito, Yoshinori Nishimoto,　Yutaka Shimoe, Akiko Shirata, Kiyomi Yamane, Sohei Yanagawa, Mikio Hirayama, Masato Tamura, Toshiki Mizuno, Masatoyo　Nishizawa, and Osamu Onodera.
- Organizer
  9th International Congress on Vascular Dementia; ICVD 2015
- Place of Presentation
  Ljubljana, Slovenija
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293200
[Presentation] D１ドーパミン受容体の発現の減少はマウスの運動量の低下を誘導する2015
- Author(s)
  笹岡俊邦, 佐藤朝子, 大久保直, 藤澤信義, 佐藤俊哉, 小田佳奈子, 前田宜俊,田中稔, 山本美丘, 酒井清子, 神保幸弘, 千葉さおり, 馬川恵梨子, 横山峯介
- Organizer
  平成27年度日本生化学会関東支部例会第56回新潟生化学懇話会
- Place of Presentation
  新潟日報メディアシップ6F (新潟県新潟市)
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] 神経変性疾患モデルの開発を成功に導くために2015
- Author(s)
  佐藤俊哉．
- Organizer
  東海医学会例会
- Place of Presentation
  東海大学医学部（神奈川県・伊勢原市）
- Year and Date
  2015-02-12
- Invited
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] Overexpression of intrinsic TDP-43 by disruption of the autoregulation in vivo.2015
- Author(s)
  Akihiro Sugai, Taisuke Kato, Masatoyo Nishizawa, Osamu Onodera.
- Organizer
  EMBO | EMBL Symposia Mechanisms of Neurodegeneration
- Place of Presentation
  Heidelberg (Germany)
- Year and Date
  2015-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] D1 dopamine receptor-mediated signal is required to maintain normal motor activity.2015
- Author(s)
  Sasaoka T, Sato A, Chiken S, Maeshima J, Arai S, Sunayama-Morita T, Oda K, Maeda Y, Sakai S, Jinbo Y, Umakawa E, Sato T, Okubo T, Fujisawa N, Yokoyama M, Nambu A.
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際展示場 (兵庫県神戸市)
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] 初期胚の体外培養がマウスの個体発生に及ぼす影響.2014
- Author(s)
  小田佳奈子,佐藤俊哉,前田宜俊,酒井清子,藤澤信義,横山峯介,笹岡俊邦
- Organizer
  第44回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学脳研究所（新潟県・新潟市）
- Year and Date
  2014-08-01
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] 人工ヌクレアーゼ技術による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用2014
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，西澤正豊，小野寺理，横山峯介，笹岡俊邦．
- Organizer
  第55回新潟生化学懇話会
- Place of Presentation
  長岡技術科学大学（新潟県・長岡市）
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] 人工ヌクレアーゼ技術による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用2014
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，西澤正豊，小野寺理，横山峯介，笹岡俊邦
- Organizer
  第44回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学脳研究所（新潟県・新潟市）
- Year and Date
  2014-08-01
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] 神経変性疾患モデルの開発を志して2014
- Author(s)
  佐藤俊哉．
- Organizer
  第31回動物生殖工学研究会
- Place of Presentation
  北里本館（東京都・港区）
- Year and Date
  2014-12-06
- Invited
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] 人工ヌクレアーゼ技術による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用2014
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，西澤正豊，小野寺理，横山峯介，笹岡俊邦
- Organizer
  第55回新潟生化学懇話会
- Place of Presentation
  長岡技術科学大学（新潟県・長岡市）
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] MRI Features of Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy.2013
- Author(s)
  Hiroaki Nozaki, Yumi Sekine, Toshio Fukutake, Yoshinori Nishimoto, Mamoru Shibata, Akiko Shirata, Kiyomi Yamane, Yutaka Shimoe, Sohei Yanagawa, Mikio Hirayama, Imaharu Nakano, Norihiro Suzuki, Masatoyo Nishizawa, Osamu Onodera.
- Organizer
  The 8th International Congress on Vascular Dementia
- Place of Presentation
  アテネギリシャ
- Data Source
  KAKENHI-PROJECT-25293200
[Presentation] TDP-43 is autoregulated by multiple excisions of introns in exon6 and reservation of mRNA in nucleus by TDP-432013
- Author(s)
  Akihide Koyama, Akihiro Sugai, Taisuke Kato, Takuya Konno, Tomohiko Ishihara, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  24th International Symposium on ALS/MND
- Place of Presentation
  Milan　イタリア
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Alternative splicing or polyadenylation, which is the major mechanism for auto-regulation of TDP-43?2013
- Author(s)
  Akihiro Sugai, Akihide Koyama, Taisuke Kato, Takuya Konno, Tomohiko Ishihara, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  RNA Metabolism in Neurological Disease:8th Brain Research Conference
- Place of Presentation
  SanDiego アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Zinc Finger Nucleaseを用いたTDP-43遺伝子改変マウスの作成2012
- Author(s)
  佐藤俊哉
- Organizer
  第42回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター(新潟県)
- Year and Date
  2012-08-04
- Data Source
  KAKENHI-PROJECT-22590925
[Presentation] Tardbp欠損マウスのmRNA選択的スプライシングと組織特異的な多様性Tardbp alternatively spliced mRNA andtissue-specific variation inheterozygous Tardbp-deficient mice2011
- Author(s)
  廣川祥子,佐藤俊哉,石原知彦,藤野赳至,近藤千草,横山峯介,崎村健司,西澤正豊,小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Tardbp欠損マウスのmRNA選択的スプライシングと組織特異的な多様性Tar dbp alternatively spliced mRNA and tissue-specific variation in heterozy gous Tardbp-deficient mice2011
- Author(s)
  廣川祥子, 佐藤俊哉, 石原知彦, 藤野赳至, 近藤千草, 横山峯介, 崎村健司, 西澤正豊, 小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] 人工制限酵素による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，笹岡俊邦，西澤正豊，小野寺理，横山峯介．
- Organizer
  第43回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター（新潟県）
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] Zinc Finger Nucleaseを用いたTDP-43遺伝子改変マウスの作成
- Author(s)
  佐藤俊哉
- Organizer
  第42回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター（新潟県）
- Data Source
  KAKENHI-PROJECT-22590925
[Presentation] TDP-43 C-terminal deficient mice exhibit a loss-of-function phenotype with up-regulated Tardbp mRNA.
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，西澤正豊，笹岡俊邦，小野寺理，横山峯介．
- Organizer
  第5回新潟大学脳研究所共同研究拠点国際シンポジウム
- Place of Presentation
  新潟大学脳研究所（新潟県・新潟市）
- Year and Date
  2015-03-05 – 2015-03-06
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] 人工制限酵素による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，笹岡俊邦，西澤正豊，小野寺理，横山峯介．
- Organizer
  第4回新潟大学脳研究所共同研究拠点国際シンポジウム
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター（新潟県）
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] GFβ1過剰発現マウスでは脳小血管壁細胞の異常をきたす
- Author(s)
  関根有美、加藤泰介、野崎洋明、廣川祥子、佐藤俊哉、志賀篤、笹岡敏邦、西澤正豊、小野寺理
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡市　福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25293200
[Presentation] Endogenous TDP-43 over-expression model with disrupted auto-regulation
- Author(s)
  Akihiro Sugai, Taisuke Kato, Akihide Koyama, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  10th Annual Meeting of the Oligonucleotide Therapeutics Society.
- Place of Presentation
  Hilton San Diego Resort & Spa, San Diego, California
- Year and Date
  2014-10-12 – 2014-10-15
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Update in amyotrophic lateral sclerosis
- Author(s)
  Osamu Onodera, Masatoyo Nishizawa, Hitoshi Takahashi
- Organizer
  The XVIII International Congress of Neuropathology. ICN 2014
- Place of Presentation
  Rio de Janeiro, Brazil
- Year and Date
  2014-09-14 – 2014-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] 人工ヌクレアーゼ技術による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，西澤正豊，小野寺理，横山峯介，笹岡俊邦．
- Organizer
  第44回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学脳研究所（新潟県・新潟市）
- Year and Date
  2014-07-31 – 2014-08-02
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] 人工制限酵素による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，廣川祥子，永田史也，前田宜俊，藤澤信義，西澤正豊，小野寺理，横山峯介．
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] Ｄ１ドーパミン受容体の発現抑制によりマウスの自発運動量が低下する
- Author(s)
  笹岡俊邦、佐藤朝子、新井慧、前島純、大久保直、藤澤信義、佐藤俊哉、小田佳奈子、前田宜俊、田中稔、山本美丘、酒井清子、神保幸弘、千葉さおり、横山峯介
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] 初期胚の体外培養がマウスの個体発生に及ぼす影響.
- Author(s)
  小田佳奈子,佐藤俊哉,前田宜俊,酒井清子,藤澤信義,横山峯介,笹岡俊邦.
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] 人工制限酵素による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，笹岡俊邦，横山峯介．
- Organizer
  第2回新潟大学医学系基礎・臨床研究交流会
- Place of Presentation
  新潟大学医学部大講義室（新潟県）
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] Analysis of the physiological function of TDP-43 using the C-terminal deficient mice established by zinc finger nuclease
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，西澤正豊，笹岡俊邦，小野寺理，横山峯介．
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場（神戸）
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] 人工制限酵素による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用
- Author(s)
  佐藤俊哉
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-22590925
[Presentation] Effect of in vitro culture of an early embryo on development of a mouse.
- Author(s)
  Kanako Oda, Toshiya Sato,Yoshitaka Maeda, Seiko Sakai, Yukihiro Jimbo Nobuyoshi Fujisawa, Minesuke Yokoyama, Toshikuni Sasaoka.
- Organizer
  第5回新潟大学脳研究所共同研究拠点国際シンポジウム,BRI International Symposium,2015.
- Place of Presentation
  新潟大学脳研究所（新潟県・新潟市）
- Year and Date
  2015-03-05 – 2015-03-06
- Data Source
  KAKENHI-PROJECT-26290029
[Presentation] 新潟大学脳研究所動物実験施設の改修工事　－その3　施設運用開始と問題点－
- Author(s)
  前田宜俊,小田佳奈子,酒井清子,永田史也,神保幸弘,田中稔,山本美丘,千葉さおり,佐藤俊哉,藤澤信義,横山峯介,笹岡俊邦
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26290029

1. ONODERA Osamu (20303167)

# of Collaborated Projects: 6 results

# of Collaborated Products: 20 results
2. KAKITA Akiyoshi (80281012)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. NISHIZAWA Masatoyo (80198457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. TOYOSHIMA Yasuko (20334675)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KODERA YOSHIO (60265733)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. FUJISAWA Nobuyoshi (50199311)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
7. ABE Manabu (10334674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUWANO Ryozo (20111734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NOZAKI Hiroaki (20547567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ISHIHARA Tomohiko (70612232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. KOYAMA Akihide (90622209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SASAOKA Toshikuni (50222005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
13. YOKOYAMA Minesuke (40090930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. IDA Hiroko (60293213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MARUYAMA Satoshi (30397161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. CHENG Jun (40207460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SAKU Takashi (40145264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SUZUKI Makoto (50107778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 高橋均 (90206839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 横関明男 (90515719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 前田宜俊 (00754524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
22. 小田佳奈子 (60708212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
23. 大久保直 (10450719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
24. 佐藤朝子 (10465932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
25. 板倉誠 (30398581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. SACHIKO Hirokawa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. NAKAO Satohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
28. NAMBU Atsushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
29. CHIKEN Satomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
30. NAKAMURA Toru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 片山泰一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 籾山俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
33. 木津川尚史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sato Toshiya 佐藤 俊哉

SATOU Toshiya 佐藤 俊哉

SATO Toshiya 佐藤 俊哉

Research Projects

Research Products

Co-Researchers

TDP-43 GaroS2領域のリン酸化による機能変化とALS病態との関連解明Principal Investigator

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Exploring primary amino acid structures and post-translational modifications that regulate nuclear import of TDP-43Principal Investigator

Principal Investigator

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Review Section

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Principal Investigator

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Research Institution

Principal Investigator

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Principal Investigator

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Establishment of TDP-43 C-terminal deficient mice using zinc finger nuclease and application to the model for amyotrophic lateral sclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

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Analysis of TDP-43 functions and modeling for ALS using conditional knockout micePrincipal Investigator

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[Journal Article] Importance of the Q/N-rich segment for protein stability and activity of endogenous mouse TDP-432022

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[Journal Article] Importance of the Q/N-rich Segment for Protein Stability and Activity of Endogenous Mouse TDP-432021

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Sato Toshiya 佐藤俊哉

SATOU Toshiya 佐藤俊哉

SATO Toshiya 佐藤俊哉