Yamamoto Koji 山本晃士

… Alternative Names

YAKMAMOTO Koji 山本晃士

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Researcher Number	90362251
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2015: 埼玉医科大学, 医学部, 教授 2012 – 2014: 名古屋大学, 医学部附属病院, 講師 2005 – 2010: Nagoya University, University Hospital, Assistant Professor, 医学部附属病院, 講師 2003 – 2004: Nagoya University, University Hospital, Research Associate, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Hematology Except Principal Investigator Hematology / General surgery / Laboratory medicine / Hematology
Keywords	Principal Investigator 線溶 / サイトカイン / 脂肪細胞 / ストレス / 血栓症 / Adipocyte / Cytokine / Stress / Fibrinolysis / Thrombosis … More / 糖尿病 / 肥満 / Lone flight thrombosis / Gene expression / Fibrin / エコノミー症候群 / ロングフライト症候群 / 遺伝子発現 / フィブリン / Atherosclerosis / Diabetes / Obesity / 動脈硬化 / 敗血症 / 神経細胞 / 交感神経 / 腎糸球体 / 菌体毒素 / 血栓 / 心筋細胞 / 血管内皮細胞 / 突然死 / PAI-1 / 炎症 / 老化 / 高血圧 … More Except Principal Investigator May-Hegglin anomaly / MYH9 / NMMHCA / PAI-1 / Knock out / thrombosis / platelet / Polymerase chain reaction / GPIb / von Willebrand factor / 免疫順応 / Organ transplantation / Endo-β-galactosidase / Accommodation / Antibody-mediated rejection / Antibody / Antigen / ABO blood group / 臓器移植 / endo-beta-galactosidase / 液性拒絶反応 / 抗体 / 抗原 / ABO血液型 / Knock in mouse / Alport symptom / Knock out mouse / immunostaining / macrothrombocytopenia / 巨大血小板 / Cre-recombinase / ノックイン / ノックインマウス / Alport徴候 / 欠失マウス / 免疫染色解析 / May-Hegglin異常症 / 巨大血小板性血小板減少症 / obese / aged, older / TF / restraint stress / thrombotic diseases / stress / competitive RT-PCR法 / マウス / 血栓傾向 / in situ hybridization法 / 加齢 / 抗TNF-α抗体 / 老齢 / TF(組織因子)発現 / 肥満 / 加齢(老齢) / TF(組織因子) / 拘束ストレス負荷 / 血栓性疾患 / ストレス / homologous recombination / alanie scanning mutagenesis / Platelet / 細胞療法 / 再生医学 / ケモカイン / 造血微小環境 / 脂肪由来間葉系幹細胞 / シグナル伝達 / 凝固 / 補体 / 血管内皮細胞 / 抗原抗体反応 / 異種移植 / ABO血液型不適合移植 / PS mRNA / エストラディオール(E2) / HepG2細胞 / ルシフェラーゼ・レポーター解析 / プロモーター / 遺伝子欠失 / PROS1遺伝子 / プロテインS(PS)欠損症 Less

Elucidation of mechanisms under prothrombotic state with agingPrincipal Investigator
- Principal Investigator
  
  Yamamoto Koji
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Saitama Medical University
  Nagoya University
Dynamic analysis of antigen, antibody, complement, inflammation and coagulation related to rejection, accommodation and tolerance
- Principal Investigator
  
  KOBAYASHI Takaaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Nagoya University
Cell therapy using adipose tissue-derived mesenchymal stem cells for primary myelofibrosis
- Principal Investigator
  
  NAKAYAMA Takayuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Elucidation of molecular pathogenesis and control of thrombosis in metabolic syndromePrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Koji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Elucidation of Molecular basis of inherited and acquired protein S deficiency as a thrombosis risk factor
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Analysis and regulation of aberrant expression of sties-responsive prothrombotic genes in a model of myocardial and cerebral infarctionPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Koji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Antigen removal in grafts and induction of accommodation for overcoming ABO incompatibility
- Principal Investigator
  
  KOBAYAHSI Takaaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nagoya University
Molecular mechanisms of thrombosis in mouse model induced by age and stress
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Analysis on thrombotic tendency in obesity and diabetes by use of model mousePrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Koji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Molecular mechanisms of thrombosis in mouse model induced by age and stress
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
The physiological role of the interaction of VWF-GPIb : Amino acid residues of the platelet GPIb to bind VWF and the generation of knock-in mice mutated at Lys599 to A1a.
- Principal Investigator
  
  MATSUSHITA Tadashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 Other

All Journal Article Presentation Book Patent Other

[Book] 血液専門医テキスト改訂第２版2015
- Author(s)
  山本晃士
- Total Pages
  584
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-24591421
[Book] 新・血栓止血血管学2015
- Author(s)
  山本晃士
- Total Pages
  251
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-24591421
[Book] 基本薬の選び方と使い方のコツ「貧血治療薬（鉄剤）」2013
- Author(s)
  山本晃士、大花正也、水野成人、羽白高、田中清、加藤徹、野出孝一、辻井悟、石井均、平塚いづみ、山田祐一郎、鳥居洋太、入谷修司、尾崎紀夫、小林孝文、中村道三、阪口正和、青山武、増山理、横田良司、他
- Total Pages
  342
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-24591421
[Book] 別冊日本臨床　血液症候群（第２版）III－その他の血液疾患を含めて－「先天性プロテインＣ欠乏症・異常症」2013
- Author(s)
  山本晃士、辻肇、鈴木宏冶、高木夕希、岡本貴行、高橋幸博、一瀬白帝、尾崎司、大山陽子、平瀬主税、田中宏和、井山諭、平山泰生、亀田拓郎、久冨木庸子、北中明、高松泰、小松則夫、田中淳司、佐藤勉、他
- Total Pages
  767
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-24591421
[Journal Article] Long acting recombinant coagulation factor IX albumin fusion protein (rIX-FP) in hemophilia B: Results of a phase 3 trial.2016
- Author(s)
  Santagostino E, Martinowitz U, Lissitchkov T, Pan-Petesch B, Hanabusa H, Oldenburg J, Boggio L, Negrier C, Pabinger I, von Depka-Prondzinski M, Altisent C, Castaman G, Yamamoto K, Álvarez-Román M-T, Voigt C, Blackman N, Jacobs I, for the PROLONG-9FP Investigators Study Group.
- Journal Title
  
  Blood
  
  Volume: in press Issue: 14 Pages: 1761-1769
- DOI
  10.1182/blood-2015-09-669234
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591421
[Journal Article] Functional Difference between Membrane-Bound and Soluble Human Thrombomodulin.2015
- Author(s)
  Miwa Y, Yazaki S, Iwamoto M, Suzuki S, Iwasaki K, Haneda M, Yamamoto K, Maruyama S, Onishi A, Kobayashi T.
- Journal Title
  
  Transplantation
  
  Volume: 99 Issue: 4 Pages: 702-709
- DOI
  10.1097/tp.0000000000000571
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293335, KAKENHI-PROJECT-25461942, KAKENHI-PROJECT-24591421
[Journal Article] 日本輸血・細胞治療学会による学会認定・アフェレーシスナース制度の導入．2015
- Author(s)
  池田和眞、井関徹、奥山美樹、山本晃士、金森平和、松﨑浩史、室井一男、大戸斉
- Journal Title
  
  日本輸血細胞治療学会誌
  
  Volume: 61 Pages: 567-570
- NAID
  130005125959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591421
[Journal Article] 加齢と血栓傾向．2015
- Author(s)
  山本晃士
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 26 Pages: 265-271
- NAID
  130005078051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591421
[Journal Article] Angiotensin II receptor blocker ameliorates stress-induced adipose tissue inflammation and insulin resistance.2014
- Author(s)
  Hayashi M, Takeshita K, Uchida Y, Yamamoto K, Kikuchi R, Nakayama T, Nomura E, Cheng XW, Matsushita T, Nakamura S, Murohara T.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 12 Pages: e116163-e116163
- DOI
  10.1371/journal.pone.0116163
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25461336, KAKENHI-PROJECT-25461445, KAKENHI-PROJECT-26461435, KAKENHI-PROJECT-26860367
[Journal Article] Recovery of flow-mediated vasodilatation after repetitive measurements is involved in early vascular impairment: comparison with indices of vascular tone.2014
- Author(s)
  Inaba H, Takeshita K, Uchida Y, Hayashi M, Okumura T, Hirashiki A, Yoshikawa D, Ishii H, Yamamoto K, Nakayama T, Hirayama M, Matsumoto H, Matsushita T, Murohara T
- Journal Title
  
  PLOS one
  
  Volume: 9(1) Issue: 1 Pages: 1-9
- DOI
  10.1371/journal.pone.0083977
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591382, KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25461336, KAKENHI-PROJECT-26461435
[Journal Article] Fibrinogen concentrate administration attributes to significant reductions of blood loss and transfusion requirements in thoracic aneurysm repair.2014
- Author(s)
  Yamamoto K, Usui A, Takamatsu J.
- Journal Title
  
  J Cardiovasc Surg
  
  Volume: 9 Issue: 1 Pages: 90-90
- DOI
  10.1186/1749-8090-9-90
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591421
[Journal Article] Comparison of the efficacy of ribavirin plus peginterferon alfa-2b for chronic hepatitis C infection in patients with and without coagulation disorders.2013
- Author(s)
  Honda T, Katano Y, Kuzuya T, Hayashi K, Ishigami M, Itoh A, Hirooka Y, Nakano I, Ishikawa T, Toyoda H, Kumada T, Yamamoto K, Matsushita T, Kojima T, Takamatsu J, Goto H
- Journal Title
  
  J Med Virol.
  
  Volume: 85(2) Issue: 2 Pages: 228-234
- DOI
  10.1002/jmv.23444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-23590970, KAKENHI-PROJECT-23592689, KAKENHI-PROJECT-24591421
[Journal Article] フィブリノゲン製剤等の適正使用に対する提言についての意見．2013
- Author(s)
  山本晃士
- Journal Title
  
  日本輸血・細胞治療学会誌
  
  Volume: 59 Pages: 752-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591421
[Journal Article] Stress Augments Insulin Resistance and Prothrombotic State : Role of Visceral Adipose-Derived Monocyte Chemoattractant Protein-12012
- Author(s)
  Uchida Y
- Journal Title
  
  Diabetes
  
  Volume: (In press) Issue: 6 Pages: 1552-61
- DOI
  10.2337/db11-0828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591059, KAKENHI-PROJECT-23591382, KAKENHI-PROJECT-24591421
[Journal Article] 産科大量出血の病態と輸血治療．2012
- Author(s)
  山本晃士
- Journal Title
  
  日本輸血・細胞治療学会誌
  
  Volume: 58 Pages: 745-752
- NAID
  10031147621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591421
[Journal Article] Production of cloned pigs expressing human thrombomodulin in endothelial cells2012
- Author(s)
  Yazaki S, Iwamoto M, Onishi A, Miwa Y, Hashimoto M, Oishi T, Suzuki S, Fuchimoto D, Sembon S, Furusawa T, Liu D, Nagasaka T, Kuzuya T, Ogawa H, Yamamoto K, Iwasaki K, Haneda M, Maruyama S, Kobayashi T.
- Journal Title
  
  Xenotransplantation
  
  Volume: 19 Issue: 2 Pages: 82-91
- DOI
  10.1111/j.1399-3089.2012.00696.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380168, KAKENHI-PROJECT-22591403, KAKENHI-PROJECT-24591421
[Journal Article] 生体肝移植レシピエント術中の凝固系管理～輸血量を減らす工夫～．2012
- Author(s)
  山本晃士
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 2 Pages: 13-19
- Data Source
  KAKENHI-PROJECT-24591421
[Journal Article] Donor screening algorithm for exclusion of thrombophilia during evaluation of living donor liver transplantation.2011
- Author(s)
  Ogawa H, Fujimoio Y, Yamamoto K, Hata T, Nagai S, Kamei H, Arikawa T, Nakamura T, Kiuchi T.
- Journal Title
  
  Clinical Transplantation
  
  Volume: 印刷中(未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Pitavastatin-induced angiogenesis and arteriogenesis is mediated by Notch1 in a murine hindlimb ischemia model without induction of VEGF2011
- Author(s)
  Kikuchi R, Takeshita K, Kondo M, Uchida Y, Cheng XW, Nakayama T, Yamamoto K, Matsushita T, Liao J, Murohara T
- Journal Title
  
  Laboratory Investigation 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Donor screening algorithm for exclusion of thrombophilia during evaluation of living donor liver transplantation.2011
- Author(s)
  Ogawa H, Fujimoto Y, Yamamoto K, Hata T, Nagai S, Kamei H, Arikawa T, Nakamura T, Kiuchi T.
- Journal Title
  
  Clinical Transplantation 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Adipose tissue-derived mesenchymal stem cells facilitate hematopoiesis in vitro and in vivo : advantages over bone marrow-derived mesenchymal stem cells.2010
- Author(s)
  Nakao N, Nakayama T, Yahata T, Muguruma Y, Saito S, Miyata Y, Yamamoto K, Naoe T.
- Journal Title
  
  American Journal of Pathology 177
  
  Pages: 547-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Adipose Tissue-Derived Mesenchymal Stem Cells Facilitate Hematopoiesis In Vitro and In Vivo.2010
- Author(s)
  中尾典彦、中山享之、八幡崇、六車ゆかり、齋藤繁紀、宮田泰彦、山本晃士、直江知樹
- Journal Title
  
  The American Journal of Pathology 177(2)
  
  Pages: 547-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591118
[Journal Article] A novel splice site mutation in intron C of PROS1 leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.2010
- Author(s)
  Okada H, Kunishima S, Hamaguchi M, Takagi A, Yamamoto K, Takamatsu J, Matsushita T, Saito H, Kojima T, Yamazaki T.
- Journal Title
  
  Thrombosis Research
  
  Volume: 125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation.2010
- Author(s)
  Miyawaki Y, Suzuki A, Fujimori Y, Takagi A, Murate T, Suzuki N, Katsumi A, Naoe T, Yamamoto K, Matsushita T, Takamatsu J, Kojima T.
- Journal Title
  
  International Journal of Hematology
  
  Volume: 92 Pages: 405-408
- NAID
  10026712691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Adipose tissue-derived mesenchymal stem cells facilitate hematopoiesis in vitro and in vivo : advantages over bone marrow-derived mesenchymal stem cells.2010
- Author(s)
  Nakao N, Nakayama T, Yahata T, Muguruma Y, Saito S, Miyata Y, Yamamoto K, Naoe T.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 177 Pages: 547-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] PAI-1の臨床的意義.2010
- Author(s)
  山本晃士
- Journal Title
  
  日本医事新報
  
  Volume: 4488 Pages: 81-83
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] PAI-1の臨床的意義2010
- Author(s)
  山本晃士
- Journal Title
  
  日本医事新報 4488
  
  Pages: 81-83
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] A novel splice site mutation in intron C of PROS1 leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.2010
- Author(s)
  Okada H, Kunishima S, Hamaguchi M, Takagi A, Yamamoto K, Takamatsu J, Matsushita T, Saito H, Kojima T, Yamazaki T.
- Journal Title
  
  Thrombosis Research 125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] メタボリックシンドロームと血栓症.2010
- Author(s)
  山本晃士
- Journal Title
  
  最新医学「血栓症」
  
  Volume: 65 Pages: 1130-1136
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] メタボリックシンドロームと血栓症2010
- Author(s)
  山本晃士
- Journal Title
  
  最新医学「血栓症」 65
  
  Pages: 1130-1136
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation.2010
- Author(s)
  Miyawaki Y, Suzuki A, Fujimori Y, Takagi A, Murate T, Suzuki N, Katsumi A, Naoe T, Yamamoto K, Matsushita T, Takamatsu J, Kojima T.
- Journal Title
  
  International Journal of Hematology 92
  
  Pages: 405-408
- NAID
  10026712691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Stress-induced PAI-1 expression is suppressed by pitavastatin in vivo.2009
- Author(s)
  Yamamoto K, Takeshita K, Kojima T, Takamatsu J.
- Journal Title
  
  International Journal of Hematology 89
  
  Pages: 553-554
- NAID
  10025161609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] A novel cholesterol absorption inhibitor, ezetimibe, decreases adipose-derived and vascular PAI-1 expression in vivo.2009
- Author(s)
  Yamamoto K, Shibayama S, Takeshita K, Kojima T, Takamatsu J.
- Journal Title
  
  Thrombosis Research 124
  
  Pages: 644-645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] γ-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice.2009
- Author(s)
  Aoyama T, Takeshita K, Kikuchi R, Yamamoto K, Cheng XW, Liao JK, Murohara T.
- Journal Title
  
  Biochem. Bioph. Res. Co. 383
  
  Pages: 216-221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged to Alanine scanning mutagenesis.2008
- Author(s)
  Nakayama T, Matsushita T, Kojima T, Yamamoto K, Sadler EJ, Naoe T, Saito H.
- Journal Title
  
  International Journal of Hematology 87
  
  Pages: 363-370
- NAID
  10025158532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis2008
- Author(s)
  T Nakayama, T Matsushita, K Yamamoto, N Mutsuga, T Kojima, A Katsumi, N Nakao, JE Sadler, T Naoe, H Saito
- Journal Title
  
  Int J Hematol 87(4)
  
  Pages: 363-370
- NAID
  10025158532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] PM-1 and metabolic syndrome2008
- Author(s)
  Yamamoto, K
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis Volume19, number1
  
  Pages: 55-63
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591053
[Journal Article] PAI-1と生活習慣病2008
- Author(s)
  山本晃士
- Journal Title
  
  日本血栓止血学会誌 19
  
  Pages: 55-63
- NAID
  10026115571
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591053
[Journal Article] L1503R is a member of group I mutation and has dominant-negative effect on secretion of full-length VWF multimers: an analysis of two patients with type 2A von Willebrand disease.2008
- Author(s)
  T Kashiwagi, T Mstsushita, Y Ito, K Hirashima, N Sanda, Y Fujimori, T Yamada, K Okumura, A Takagi, T Murate, A Katsumi, J Takamatsu, K Yamamoto, T Naoe, T Kojima
- Journal Title
  
  Haemophilia 14(3)
  
  Pages: 556-563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Skewed X chromosome inactivation in fraternal female twins results in moderately severe and mild haemophilia B2008
- Author(s)
  K Okumura, Y Fujimori, A Takagi, T Murate, M Ozeki, K Yamamoto, A Katsumi, T Matsushita, T Naoe, and T Kojima
- Journal Title
  
  Haemophilia 14(5)
  
  Pages: 1088-1093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Pitavastatin attenuates the upregulation of tissue factor in restraint-stressed mice.2007
- Author(s)
  Yamamoto K, Kojima T, Takeshita K, Matsushita T, Takamatsu J
- Journal Title
  
  Thrombosis Research 120
  
  Pages: 143-144
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591407
[Journal Article] Intrarenal administration of recombinant human soluble thrombomodulin ameliorates ischaemic acute renal failure.2007
- Author(s)
  Ozaki T, Anas C, Maruyama S, Yamamoto T, Yasuda K, Morita Y, Ito Y, Gotoh M, Yuzawa Y, Matsuo S.
- Journal Title
  
  Nephrol Dial Transplant 23
  
  Pages: 110-119
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591407
[Journal Article] Pitavastatin attenuates the upregulation of tissue factor in restraint-stressed mice2007
- Author(s)
  Yamamoto, K, Kojima, T. Takeshita, K. Matsushita, T. Takamatsu, J
- Journal Title
  
  Thrombosis Research Volume120, number1
  
  Pages: 143-144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591053
[Journal Article] Intravenous immunoglobulin therapy for acquired coagulation inhibitors.2007
- Author(s)
  Yamamoto K, Takamatsu J, Saito H.
- Journal Title
  
  International Journal of Hematology 85
  
  Pages: 287-293
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591053
[Journal Article] Pitavastatin attenuates the upregulation of tissue factor in restraint-stressed mice.2007
- Author(s)
  Yamamoto, K, Kojima, T, Takeshita, K, Matsushita, T, Takamatsu, J
- Journal Title
  
  Thrombosis Rsearch 120
  
  Pages: 143-144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591407
[Journal Article] Intrarenal administration of recombinant human soluble thrombomodulin ameliorates ischaemic acute renal failure2007
- Author(s)
  Ozaki, T, Anas, C, Maruyama, S, Yamamoto, T, Yasuda, K, Morita, Y, Ito, Y, Gotoh, M, Yuzawa, Y, Matsuo, S
- Journal Title
  
  Nephrol Dial Transplant 23
  
  Pages: 110-119
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591407
[Journal Article] Pitavastatin attenuates the upregulation of tissue factor in restraint-stressed mice.2007
- Author(s)
  Yamamoto K, Kojima T, Takeshita K, Matsushita T, Takamatsu J.
- Journal Title
  
  Thrombosis Research 120
  
  Pages: 143-144
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591053
[Journal Article] Intravenous immunoglobulin therapy for acquired coagulation inhibitors2007
- Author(s)
  Yamamoto, K, Takamatsu, J, Saito, H
- Journal Title
  
  International Journal of Hematology Volume85, number4
  
  Pages: 287-293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591053
[Journal Article] Molecular basis of antithrombin deficiency in four Japanese patients with antithrombin gene abnormalities including two novel mutations2007
- Author(s)
  M Kyotani, K Okumura, A Takagi, T Murate, K Yamamoto, T Matsushita, M Sugimura, N Kanayama, T Kobayashi, H Saito, T Kojima
- Journal Title
  
  Am J Hematol 82(2)
  
  Pages: 702-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Obesity enhances the induction of plasminogen activator inhibitor-1 by restraint stress : a possible mechanism of stress-induced renal fibrin deposition in obese mice.2005
- Author(s)
  K.Yamamoto, et al.
- Journal Title
  
  J.thromb.Haemost. 3
  
  Pages: 1495-1502
- Data Source
  KAKENHI-PROJECT-17590490
[Journal Article] Obesity enhances the induction of plasminogen activator inhibitor-1 by restraint stress : a possible mechanism of stress-induced renal fibrin deposition in obese mice.2005
- Author(s)
  Yamamoto K, Kojima T, Adachi T, Hayashi M, Matsushita T, Takamatsu J, Loskutoff DJ, Saito H.
- Journal Title
  
  Journal of Thrombosis and Haemostasis 3巻・7号
  
  Pages: 1495-1502
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590934
[Journal Article] Obesity enhances the induction of plasminogen activator inhibitor-1 by restraint stress : a possible mechanism of stress-induced renal fibrin deposition. In obese mice.2005
- Author(s)
  Yamamoto K, Kojima T, Adachi T, Hayashi M, Matsushita T, Takamatsu J, Loskutoff DJ, Saito H.
- Journal Title
  
  Journal of Thrombosis and Haemostasis Volume 3 - number 7
  
  Pages: 1495-1502
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590934
[Journal Article] Aging and plasminogen activator inhibitor-1 (PAI-1) regulation : implication in the pathogenesis of thrombotic disorders in the elderly.2005
- Author(s)
  K.Yamamoto, et al.
- Journal Title
  
  Cardiovas.Res. 66
  
  Pages: 276-285
- Data Source
  KAKENHI-PROJECT-17590490
[Patent] 血液凝固第VII 因子プロモーターの活性化剤及びその利用2007
- Inventor(s)
  本多隆、高松純樹、豊田秀徳、山本晃士、後藤秀実、小嶋哲人
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Filing Date
  2007-08-27
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 貯血式自己血における前置・低位胎盤症例の最適な自己血貯血量．2016
- Author(s)
  酒井あゆみ、松永茂剛、舘　明子、阿南昌弘、江良澄子、小野義久、髙井　泰、斉藤正博、山本晃士、関　博之、前田平生
- Organizer
  第29回日本自己血輸血学会学術総会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] Qualified apheresis nurse certification by the Japan Society of Transfusion Medicine and Cell Therapy to promote safety and efficiency in apheresis through encouraging learning.2015
- Author(s)
  Ikeda K, Iseki T, Yamamoto K, Okuyama Y, Kanamori H, Matsuzaki K, Muroi K, Ohto H.
- Organizer
  The 25th Regional Congress of the International Society of Blood Transfusion
- Place of Presentation
  ロンドン（イギリス）
- Year and Date
  2015-06-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] 産科DICによる大量出血の病態と止血治療．2015
- Author(s)
  山本晃士
- Organizer
  第119回日本産科麻酔学会学術集会
- Place of Presentation
  都市センターホテル（東京都千代田区）
- Year and Date
  2015-11-28
- Invited
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] Accelerated activation of the coagulation pathway during cardiopulmonary bypass in aortic replacement surgery: a suggested hemostatic therapy for critical intraoperative coagulopathy.2015
- Author(s)
  Yamamoto K
- Organizer
  Pioneer Century Science World Congress of Cardiothoracic-Renal Disease-2015
- Place of Presentation
  ワルシャワ（ポーランド）
- Year and Date
  2015-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] Efficacy and safety results of a phase III pivotal clinical study of recombinant fusion protein linking coagulation factor IX with albumin (RIX-FP) in previously treated patients with hemophilia B.2015
- Author(s)
  Santagostino E, Martinowitz U, Lissitchkov T, Pan-Petesch B, Hanabusa H, Oldenburg J, Boggio L, Negrier C, Pabinger-Fasching I, von Depka-Prondzinski M, Altisent C, Castaman G, Yamamoto K, Román MA, Voigt C, Jacobs I, PROLONG-9FP Investigators.
- Organizer
  XXV Congress, International Society of Thrombosis and Haemostasis
- Place of Presentation
  トロント（カナダ）
- Year and Date
  2015-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] 外科領域の止血不全における線溶亢進と第XIII因子の重要性．2015
- Author(s)
  山本晃士
- Organizer
  第9回日本血栓止血学会SSCシンポジウム
- Place of Presentation
  野村コンファレンスプラザ日本橋（東京都中央区）
- Year and Date
  2015-02-28
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] 大量出血時の止血検査と輸血療法．2014
- Author(s)
  山本晃士
- Organizer
  第21回日本輸血・細胞治療学会秋季シンポジウム
- Place of Presentation
  ひめぎんホール（愛媛県松山市）
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] 大量出血におけるクリオプレシピテートおよびフィブリノゲン製剤の投与効果．2013
- Author(s)
  山本晃士
- Organizer
  第61回日本輸血・細胞治療学会総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] 産科大量出血の病態と輸血治療．2012
- Author(s)
  山本晃士
- Organizer
  第48回日本周産期・新生児医学会
- Place of Presentation
  大宮ソニックシティ（埼玉県さいたま市）
- Invited
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] 重症患者に対するアルブミン製剤投与の医学的意義．2012
- Author(s)
  山本晃士
- Organizer
  第38回日本熱傷学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Invited
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] 先天性凝固第VII 因子欠損症の分子病態解析2008
- Author(s)
  田中亮子、中島大輔、鈴木敦夫、宮脇由理、藤森祐多、山田貴之、奥村薫、勝見章、山本晃士、松下正、高松純樹、高木明、村手隆、小嶋哲人
- Organizer
  第31回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 先天性プロテインC欠損症7家系における遺伝子解析2007
- Author(s)
  田中亮子、中島大輔、柏木隆宏、三田直美、藤森祐多、山田貴之、奥村薫、勝見章、松下正、山本晃士、高松純樹、高木明、村手隆、小嶋哲人
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  志摩
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] A pathological role of PAI-1 in metabolic syndrome2007
- Author(s)
  Yamamoto, K
- Organizer
  39th Japanese Society of Atherosclerosis
- Place of Presentation
  Osaka
- Year and Date
  2007-07-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591053
[Presentation] Beneficial Fffect of Human DAF and Thrombomodulin Expression in Pig Endothelial Cells on Coagulation Control2007
- Author(s)
  Miwa, Y, Kobayashi, T, Yamamoto, K, Nagasaka, T, DaGe, Liu, Kuzuya, T, Onishi, A, Kadomatsu, K, Uchida, K, Nakao, A
- Organizer
  American Transplant Congress 2007
- Place of Presentation
  San Francisco (USA)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591407
[Presentation] Significance of human DAF and thrombomodulin gene transfer for coagulation control in pig to human xenotransplantation2007
- Author(s)
  Y. Miwa, K. Yamamoto, A. Katayama, T. Nagasaka, A. Onishi, M. Iwamoto, K. Kadomatsu, K. Uchida, A. Nakao, T. Kobayashi
- Organizer
  CTS-IPITA-IXA2007 Joint Conference
- Place of Presentation
  Minneapolis (USA)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591407
[Presentation] Molecular basis of antithrombin deficiency in four Japanese patients with pregnancy-associated thrombosis : antithrombin gene abnormalities including two novel mutations2007
- Author(s)
  K. Okumura, Y. Fujimori, T. Kashiwagi, N. Sanda, T. Yamada, A. Takagi, T. Murate, T. Iwasaki, A. Katsumi, K. Yamamoto, T. Matsushita, T. Naoe, H. Saito, T. Kojima
- Organizer
  XXIInd Congress of ISTH, Geneva
- Place of Presentation
  Switzerland
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Beneficial Fffect of Human DAF and Thrombomodulin Expression in Pig Endothelial Cells on Coagulation Control.2007
- Author(s)
  Miwa Y, Kobayashi T, Yamamoto K, Nagasaka T, Dace Liu, Kuzuya T, Onishi A, Kadomatsu K, Uchida K, Nakao A
- Organizer
  American Transplant Congress 2007
- Place of Presentation
  San Francisco (USA)
- Data Source
  KAKENHI-PROJECT-18591407
[Presentation] The protein S thrombin sensitive region contributes regulation of warfarin treated des-γ-carboxylated protein S secretion: a study of a novel splice site mutation of protein S gene and its molecular consequences2007
- Author(s)
  H. Okada, S. Kunishima, M. Hamaguchi, A. Takagi, K. Yamamoto, J. Takamatsu, T. Matsushita, H. Saito, T. Kojima, T. Yamazak
- Organizer
  XXIInd Congress of ISTH
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2007-07-19
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Significance of human DAF and thrombomodulin gene transfer for coagulation control in pig to human xenotransplantation2007
- Author(s)
  Y. Miwa, K. Yamamoto, A. Katayama, T. Nagasaka, A. Onishi, M. Iwamoto, K. Kadomatsu, K. Uchida, A. Nakao, T. Kobayashi
- Organizer
  CTS-IPITA-IXA 2007 Joint Conference
- Place of Presentation
  Minneapolis (USA)
- Data Source
  KAKENHI-PROJECT-18591407
[Presentation] メタボリックシンドロームにおけるPAI-1の病態学的意義2007
- Author(s)
  山本晃士
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪府
- Year and Date
  2007-07-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591053
[Presentation] Beneficial Fffect of Human DAF and Thrombomodulin Expression in Pig Endothelial Cells on Coagulation Control.2007
- Author(s)
  Miwa Y, Kobayashi T, Yamamoto K, Nagasaka T, DaGe Liu, Kuzuya T, Onishi A, Kadomatsu K, Uchida K, Nakao A
- Organizer
  American Transplant Congress 2007
- Place of Presentation
  San Francisco(USA)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591407
[Presentation] Significance of human DAF and thrombomodulin gene transfer for coagulation control in pig to human xenotransplantation2007
- Author(s)
  Y. Miwa, K. Yamamoto, A. Katayama, T. Nagasaka, A. Onishi, M. Iwamoto, K. Kadomatsu, K. Uchida, A. Nakao, T. Kobayashi
- Organizer
  CTS-IPITA-IXA 2007 Joint Conference
- Place of Presentation
  Minneapolis(USA)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591407
[Presentation] Four novel causative mutations identified in the PROS1 gene of Japanese deep vein thrombosis patients with protein S deficiency2007
- Author(s)
  N. Sanda, Y. Fujimori, T. Kashiwagi, T. Yamada, K. Okumura, A. Takagi, T. Murate, T. Iwasaki, A. Katsumi, K. Yamamoto, T. Matsushita, T. Naoe, H. Saito, T. Kojima
- Organizer
  XXIInd Congress of ISTH
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 胸部大動脈瘤手術中におけるトロンビン／フィブリン生成とフィブリノゲン値への影響－弁置換術症例との比較－．
- Author(s)
  山本晃士、佐藤秀雄、澤村成史
- Organizer
  第62回日本輸血・細胞治療学会総会
- Place of Presentation
  奈良県新公会堂（奈良県奈良市）
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] 術中大量出血におけるフィブリノゲンの重要性．
- Author(s)
  山本晃士
- Organizer
  第37回日本血栓止血学会総会シンポジウム
- Place of Presentation
  大阪国際交流センター（大阪府大阪市）
- Year and Date
  2014-05-29 – 2014-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] 心臓血管外科手術中に起こるDICの病因と病態－実症例における解析－．
- Author(s)
  山本晃士、佐藤秀雄、澤村成史
- Organizer
  第37回日本血栓止血学会総会
- Place of Presentation
  大阪国際交流センター（大阪府大阪市）
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] Irbesartan ameliorates stress-induced prothrombotic state.
- Author(s)
  Takeshita K, Yamamoto K, Hayashi M, Matsushita T, Murohara T.
- Organizer
  22th International Congress of Fibrinolysis and Proteolysis
- Place of Presentation
  マルセイユ（フランス）
- Year and Date
  2014-07-06 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] 新鮮凍結血漿の使用指針を見直す．
- Author(s)
  山本晃士
- Organizer
  第62回日本輸血・細胞治療学会総会シンポジウム
- Place of Presentation
  奈良県新公会堂（奈良県奈良市）
- Year and Date
  2014-05-05 – 2014-05-17
- Invited
- Data Source
  KAKENHI-PROJECT-24591421
[Presentation] 大量出血時におけるフィブリノゲン製剤の適応と効果．
- Author(s)
  山本晃士
- Organizer
  第20回日本輸血・細胞治療学会秋季シンポジウム
- Place of Presentation
  札幌コンベンションセンター（札幌市）
- Invited
- Data Source
  KAKENHI-PROJECT-24591421
[]

1. KOJIMA Tetsuhito (40161913)

# of Collaborated Projects: 7 results

# of Collaborated Products: 21 results
2. MATSUSHITA Tadashi (30314008)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
3. TAKAGI Akira (30135371)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. KOBAYASHI Takaaki (70314010)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. TAKEDA Shin (20314015)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MARUYAMA Shoichi (10362253)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. ONISHI Akira (30414890)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
8. OGAWA Haruko (10400079)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. HANEDA Masataka (50436995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. KISHIDA Satoshi (20402563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. IWASAKI Kenta (10508881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. NAKAYAMA Takayuki (00456659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. MIWA Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. YAMAMOTO Takayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamamoto Koji 山本 晃士

YAKMAMOTO Koji 山本 晃士

Research Projects

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Co-Researchers

Elucidation of mechanisms under prothrombotic state with agingPrincipal Investigator

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Dynamic analysis of antigen, antibody, complement, inflammation and coagulation related to rejection, accommodation and tolerance

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Cell therapy using adipose tissue-derived mesenchymal stem cells for primary myelofibrosis

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Elucidation of molecular pathogenesis and control of thrombosis in metabolic syndromePrincipal Investigator

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Elucidation of Molecular basis of inherited and acquired protein S deficiency as a thrombosis risk factor

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Analysis and regulation of aberrant expression of sties-responsive prothrombotic genes in a model of myocardial and cerebral infarctionPrincipal Investigator

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Antigen removal in grafts and induction of accommodation for overcoming ABO incompatibility

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Molecular mechanisms of thrombosis in mouse model induced by age and stress

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Analysis on thrombotic tendency in obesity and diabetes by use of model mousePrincipal Investigator

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Molecular mechanisms of thrombosis in mouse model induced by age and stress

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The physiological role of the interaction of VWF-GPIb : Amino acid residues of the platelet GPIb to bind VWF and the generation of knock-in mice mutated at Lys599 to A1a.

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[Book] 血液専門医テキスト改訂第２版2015

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Publisher

Data Source

[Book] 新・血栓止血血管学2015

Author(s)

Total Pages

Publisher

Yamamoto Koji 山本晃士

YAKMAMOTO Koji 山本晃士

[Book] 別冊日本臨床　血液症候群（第２版）III－その他の血液疾患を含めて－「先天性プロテインＣ欠乏症・異常症」2013