IWATA Takeshi 岩田岳

… Alternative Names

岩田岳イワタタケシ

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Researcher Number	90374157
Other IDs	https://orcid.org/0000-0003-1447-0081
Affiliation (Current)	2025: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 分子細胞生物学研究部, 名誉部長
Affiliation (based on the past Project Information) *help	2013 – 2020: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 分子細胞生物学研究部, 部長 2017: 独立行政法人国立病院機構, 東京医療センター臨床研究センター, 部長 2015: 国立病院機構東京医療センター, 臨床研究センター・分子細胞生物学研究部, 部長 2011: 東京医療センター臨床研究センター, 分子細胞生物学研究部, 部長 2011: 独立行政法人国立病院機構東京医療センター(臨床研究センター), 分子細胞生物学研究部, 部長 … More 2011: 独立行政法人国立病院機構東京医療センター(臨床研究センター), 分子細胞生物学研究部, 部長 2010: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 分子細胞生物学研究部, 部長 2009: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 部長 2008: 東京医療センター(臨床研究センター), 分子細胞生物学研究部, 部長 2007: 国立病院機構, 東京医療センター(臨床研究センター)・分子細胞生物学研究部, 部長 2007: National Institute of Sensory Organs, Institution, department, title of position : Division of Molecular and Cellular Biology, Department manager 2005: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 視覚研究部, 細胞・分子生物学研究室長 2005: National Hospital Organization Tokyo Medical Center, National Institute of Sensory Organs, Laboratory Head, 視覚研究部門, 室長 2004: 独立行政法人国立病院機構東京医療センター, 臨床研究センター, 室長 Less
Review Section/Research Field	Principal Investigator Ophthalmology / Surgery related to the biological and sensory functions and related fields Except Principal Investigator Ophthalmology
Keywords	Principal Investigator 眼生化学・分子生物学 / 眼科学 / 外科系臨床医学 / 医歯薬学 / Rab8 / カニクイザル / ドルーゼン / 疾患モデル動物 / 遺伝子改変 / ノックアウト … More / 霊長類 / オプチニュリン / 緑内障 / 生化学・分子生物学 / CRISPR/Cas9 / intra ocular pressure / gene mutation / quartz crystal balance / protein interaction / retinal ganglion cells / optineurin / glaucoma / アストロサイト / 正常眼圧力緑内障 / 小胞体 / タンパク質相互作用 / 網膜 / 神経節細胞 / 細胞オルガネラ / 水晶発振子 / 分子間相互作用 / 眼性化学・分子生物学 / トランスジェニックマウス / Vav3 / Vav2 / WDR36 … More Except Principal Investigator WDR36 / ERM family / Rab8 / 毛様体 / 緑内障 / 遺伝子 / アデノ随伴ウイルス / 細胞増殖 / 傷害 / 変性モデル / 再生 / グリア細胞 / 網膜 / Oculara ciliary body / Ocular ciliary body / Glaucoma / 眼圧調整機構 / 原発開放隅角緑内障 / neuroscience / protein / gene / 神経科学 / 蛋白質 / aqueous humor / intraocular pressure / glaucoma / intra ocular pressure / moesin / radixin / ezrin / ocular ciliary body / 房水 / 眼圧 / クンパク質 Less

Construction of Cynomologus Monkey Model for Hereditary Retinal Diseases : Diseases Mechanisms and TherapeuticPrincipal Investigator
- Principal Investigator
  
  Iwata Takeshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Development of disease monkey model for hereditary retinal disease by gene editingPrincipal Investigator
- Principal Investigator
  
  Iwata Takeshi
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Induction of Muller glia-derived retinal regeneration by expressing regeneration promoting genes
- Principal Investigator
  
  Okamoto Akiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Primate model to study drusen formation and development of therapeuticsPrincipal Investigator
- Principal Investigator
  
  IWATA Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Development of cynomolgus monkey with hereditary retinal diseasesPrincipal Investigator
- Principal Investigator
  
  IWATA Takeshi
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Development and pathological characterization of genetically modified macaque monkey with eye disease.Principal Investigator
- Principal Investigator
  
  IWATA Takeshi
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
The elucidation of glaucoma pathophysiology by the investigation of Rab8 and ERM family interaction in the ocular ciliary body
- Principal Investigator
  
  Kimura Itaru
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Characterization of mouse models for glaucomaPrincipal Investigator
- Principal Investigator
  
  IWATA Takeshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構東京医療センター(臨床研究センター)
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
T hestudyofinteractionbetweenRab8andERMfamily i ntheocularciliarybody
- Principal Investigator
  
  KIMURA Itaru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構東京医療センター(臨床研究センター)
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
原発開放隅角緑内障の原因遺伝子(Myocilin)の機能解析
- Principal Investigator
  
  MINAMI Masayoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Functional analysis of primary open-angle glaucoma associated WDR36 gene.
- Principal Investigator
  
  MINAMI Masayoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Analysis of glaucoma-related protein interactionPrincipal Investigator
- Principal Investigator
  
  IWATA Takeshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  National Hospital Organization Tokyo Medical Center

[Book] Advances in Vision Research Volume II, Essentials in Ophthalmology2018
- Author(s)
  Gyan Prakash and Takeshi Iwata (Eds)
- Total Pages
  468
- Publisher
  Springer Nature
- ISBN
  9789811308833
- Data Source
  KAKENHI-PROJECT-17H06276
[Book] 遺伝子医学 MOOK2018
- Author(s)
  須賀晶子、吉武和敏、岩田岳（編集：松本直道、難波栄二、古川洋一）
- Total Pages
  216
- Publisher
  オミックス解析による遺伝性網脈絡膜疾患の病因・病態機序の解明、臨床応用に向けた疾患シークエンス解析
- ISBN
  9784944157280
- Data Source
  KAKENHI-PROJECT-17H06276
[Book] Advances in Vision Research, Volume I2017
- Author(s)
  Prakash, Gyan, Iwata, Takeshi (Eds.)
- Total Pages
  523
- Publisher
  Springer
- ISBN
  9784431565116
- Data Source
  KAKENHI-PROJECT-17H06276
[Book] RETINA Medicine2014
- Author(s)
  赤堀正和、岩田岳
- Total Pages
  5
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-25670742
[Book] Animal Models for Eye Diseases, Handbook of Laboratory Animal Science III2014
- Author(s)
  Iwata T, (Editor: Hau J and Schapiro SJ)
- Total Pages
  23
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-25670742
[Book] 緑内障の遺伝子とその機能解析、緑内障の病態と疫学、高齢者の視覚障害とそのケア2013
- Author(s)
  岩田岳(編集:小口芳久)
- Publisher
  公益財団法人長寿科学振興財団
- Data Source
  KAKENHI-PROJECT-25670742
[Book] 全エクソーム解析による遺伝性網脈絡膜疾患の原因遺伝子探索、エクソーム解析‐成果と将来-(編集 : 松本直道)、医学のあゆみ2013
- Author(s)
  岩田岳、古野正朗、池尾一穂
- Total Pages
  245
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-25670742
[Book] Optineurinと正常眼圧緑内障、Digestシリーズ(編集 : 本庶佑)、Medical Science Digest2013
- Author(s)
  岩田岳
- Total Pages
  39
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-25670742
[Book] 眼科と補体、補体への招待2011
- Author(s)
  岩田岳
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-21390471
[Book] 実験医学2011
- Author(s)
  岩田岳
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21390471
[Book] 視力・色覚を司る黄斑の生理機能と黄斑変性の分子メカニズム、視覚・聴覚のNeuro science、実験医学2011
- Author(s)
  岩田岳
- Total Pages
  12
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21390471
[Book] 視力・資格を司る黄斑の生理機能と黄斑変性の分子メカニズム、実験医学2011
- Author(s)
  岩田岳
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21390471
[Book] 眼科と補体、補体への2011
- Author(s)
  岩田岳
- Total Pages
  5
- Publisher
  メディカルビュー社(招待)
- Data Source
  KAKENHI-PROJECT-21390471
[Book] 補体への招待2011
- Author(s)
  岩田岳
- Total Pages
  5
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-21390471
[Book] 緑内障遺伝子改変動物の基礎、眼薬理2009
- Author(s)
  岩田岳
- Data Source
  KAKENHI-PROJECT-21390471
[Book] 打倒!加齢黄斑変性2006
- Author(s)
  岩田岳
- Total Pages
  170
- Publisher
  メディカル・ビュー
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591779
[Book] インベーダー法を用いた緑内障の遺伝子解析2004
- Author(s)
  岩田岳, 真島行彦
- Total Pages
  7
- Publisher
  Bio Medical Quick Review Net 株式会社メディカルデゥ
- Data Source
  KAKENHI-PROJECT-16591779
[Journal Article] Spatial Functional Characteristics of East Asian Patients With Occult Macular Dystrophy (Miyake Disease); EAOMD Report No. 22021
- Author(s)
  Yang L, Joo K, Tsunoda K, Kondo M, Fujinami-Yokokawa Y, Arno G, Pontikos N, Liu X, Nakamura N, Kurihara T, Tsubota K, Iwata T, Li H, Zou X, Wu S, Sun Z, Ahn SJ, Kim MS, Mun YS, Park KH, Robson AG, Miyake Y, Woo SJ, Sui R, Fujinami K; East Asia Inherited Retinal Disease Society Study Group
- Journal Title
  
  Am J Ophthalmol
  
  Volume: 221 Pages: 169-180
- DOI
  10.1016/j.ajo.2020.07.025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02954, KAKENHI-PROJECT-18K16943, KAKENHI-PROJECT-22KJ2665, KAKENHI-PROJECT-17H06276
[Journal Article] Correction to: Clinical and genetic characteristics of 14 patients from 13 Japanese families with RPGR-associated retinal disorder: report of eight novel variants.2020
- Author(s)
  Mawatari G, Fujinami K, Liu X, Yang L, Fujinami-Yokokawa Y, Komori S, Ueno S, Terasaki H, Katagiri S, Hayashi T, Kuniyoshi K, Miyake Y, Tsunoda K, Yoshitake K, Iwata T, Nao-I N; JEGC study group.
- Journal Title
  
  Human Genome Varriation
  
  Volume: 7 Issue: 1 Pages: 1-3
- DOI
  10.1038/s41439-019-0086-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09989, KAKENHI-PROJECT-17H06276
[Journal Article] Novel mutations in malonyl-CoA-acyl carrier protein transacylase provoke autosomal recessive optic neuropathy.2020
- Author(s)
  Li H, Yuan S, Minegishi Y, Suga A, Yoshitake K, Sheng X, Ye J, Smith S, Bunkoczi G, Yamamoto M, Iwata T
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 29 Issue: 3 Pages: 444-458
- DOI
  10.1093/hmg/ddz311
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09432, KAKENHI-PROJECT-17H06276
[Journal Article] Clinical Course and Electron Microscopic Findings in Lymphocytes of Patients with DRAM2-Associated Retinopathy2020
- Author(s)
  Kuniyoshi Kazuki、Hayashi Takaaki、Kameya Shuhei、Katagiri Satoshi、Mizobuchi Kei、Tachibana Toshiaki、Kubota Daiki、Sakuramoto Hiroyuki、Tsunoda Kazushige、Fujinami Kaoru、Yoshitake Kazutoshi、Iwata Takeshi、Nakano Tadashi、Kusaka Shunji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 4 Pages: 1331-1331
- DOI
  10.3390/ijms21041331
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11434, KAKENHI-PROJECT-19K09940, KAKENHI-PROJECT-17H06276
[Journal Article] Genetic variants associated with the onset and progression of primary open-angle glaucoma2020
- Author(s)
  Mabuchi F, Mabuchi N, Sakurada Y, Yoneyama S, Kashiwagi K, Iijima H, Yamagata Z, Takamoto M, Aihara M, Iwata T, Hashimoto K, Sato K, Shiga Y, Nishiguchi KM, Nakazawa T, Akiyama M, Kawase K, Ozaki M, Araie M, Japan Glaucoma Society Omics Group (JGS-OG)
- Journal Title
  
  American Journal of Ophthalmology
  
  Volume: 212 Pages: 135-140
- DOI
  10.1016/j.ajo.2020.03.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09400, KAKENHI-PROJECT-17K11478, KAKENHI-PROJECT-20K09786, KAKENHI-PROJECT-17H06276
[Journal Article] Novel homozygous CLN3 missense variant in isolated retinal dystrophy: A case report and electron microscopic findings2020
- Author(s)
  Mizobuchi Kei、Hayashi Takaaki、Yoshitake Kazutoshi、Fujinami Kaoru、Tachibana Toshiaki、Tsunoda Kazushige、Iwata Takeshi、Nakano Tadashi
- Journal Title
  
  Molecular Genetics & Genomic Medicine
  
  Volume: 8 Issue: 8
- DOI
  10.1002/mgg3.1308
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06276
[Journal Article] Heterozygous GGC repeat expansion of NOTCH2NLC in a patient with neuronal intranuclear inclusion disease and progressive retinal dystrophy2020
- Author(s)
  Hayashi Takaaki、Katagiri Satoshi、Mizobuchi Kei、Yoshitake Kazutoshi、Kameya Shuhei、Matsuura Tomokazu、Iwata Takeshi、Nakano Tadashi
- Journal Title
  
  Ophthalmic Genetics
  
  Volume: 41 Issue: 1 Pages: 93-95
- DOI
  10.1080/13816810.2020.1723119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11434, KAKENHI-PROJECT-19K09940, KAKENHI-PROJECT-17H06276
[Journal Article] The Serine Protease HTRA-1 Is a Biomarker for ROP and Mediates Retinal Neovascularization2020
- Author(s)
  Owen Leah A.、Shirer Kinsey、Collazo Samuel A.、Szczotka Kathryn、Baker Shawna、Wood Blair、Carroll Lara、Haaland Benjamin、Iwata Takeshi、Katikaneni Lakshmi D.、DeAngelis Margaret M.
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 13 Pages: 605918-605918
- DOI
  10.3389/fnmol.2020.605918
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Journal Article] Clinical and genetic characteristics of 10 Japanese patients with PROM1-associated retinal disorder: A report of the phenotype spectrum and a literature review in the Japanese population.2020
- Author(s)
  Fujinami K, Oishi A, Yang L, Arno G, Pontikos N, Yoshitake K, Fujinami-Yokokawa Y, Liu X, Hayashi T, Katagiri S, Mizobuchi K, Mizota A, Shinoda K, Nakamura N, Kurihara T, Tsubota K, Miyake Y, Iwata T, Tsujikawa A, Tsunoda K; Japan Eye Genetics Consortium study group.
- Journal Title
  
  Am J Med Genet C Semin Med Genet.
  
  Volume: 184 Issue: 3 Pages: 656-674
- DOI
  10.1002/ajmg.c.31826
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11430, KAKENHI-PROJECT-19K09929, KAKENHI-PROJECT-18K16943, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-18K09424
[Journal Article] Progress of macular atrophy during 30 months’ follow-up in a patient with spinocerebellar ataxia type1 (SCA1)2020
- Author(s)
  Hirose Ayane、Katagiri Satoshi、Hayashi Takaaki、Matsuura Tomokazu、Nagai Norihiro、Fujinami Kaoru、Iwata Takeshi、Tsunoda Kazushige
- Journal Title
  
  Documenta Ophthalmologica
  
  Volume: 142 Issue: 1 Pages: 87-98
- DOI
  10.1007/s10633-020-09782-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06276
[Journal Article] Genetic defects of CHM and visual acuity outcome in 24 choroideremia patients from 16 Japanese families2020
- Author(s)
  Hayashi Takaaki、Kameya Shuhei、Mizobuchi Kei、Kubota Daiki、Kikuchi Sachiko、Yoshitake Kazutoshi、Mizota Atsushi、Murakami Akira、Iwata Takeshi、Nakano Tadashi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 15883-15883
- DOI
  10.1038/s41598-020-72623-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09940, KAKENHI-PROJECT-17H06276
[Journal Article] Novel mutations in the RS1 gene in Japanese patients with X-linked congenital retinoschisis2019
- Author(s)
  Kondo Hiroyuki、Oku Kazuma、Katagiri Satoshi、Hayashi Takaaki、Nakano Tadashi、et al.
- Journal Title
  
  Human Genome Variation
  
  Volume: 6 Issue: 1 Pages: 3-3
- DOI
  10.1038/s41439-018-0034-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11434, KAKENHI-PROJECT-17K19721, KAKENHI-PROJECT-18H02954, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16H06269, KAKENHI-PROJECT-16KK0193, KAKENHI-PROJECT-19K09989, KAKENHI-PROJECT-17K11441
[Journal Article] Novel biallelic loss-of-function KCNV2 variants in cone dystrophy with supernormal rod responses.2019
- Author(s)
  Kutsuma T, Katagiri S, Hayashi T, Yoshitake K, Iejima D, Gekka T, Kohzaki K, Mizobuchi K, Baba Y, Terauchi R, Matsuura T, Ueno S, Iwata T, Nakano T.
- Journal Title
  
  Doc Ophthalmol.
  
  Volume: 138(3) Issue: 3 Pages: 229-239
- DOI
  10.1007/s10633-019-09679-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-17K11434
[Journal Article] Three cases of acute-onset bilateral photophobia2019
- Author(s)
  Ueno Shinji、Inooka Daiki、Meinert Monika、Ito Yasuki、Tsunoda Kazushige、Fujinami Kaoru、Iwata Takeshi、Ohde Hisao、Terasaki Hiroko
- Journal Title
  
  Japanese Journal of Ophthalmology
  
  Volume: 63 Issue: 2 Pages: 172-180
- DOI
  10.1007/s10384-018-00649-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11320, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16H06269, KAKENHI-PROJECT-16KK0193, KAKENHI-PROJECT-19K09989
[Journal Article] Clinical findings of end-stage retinitis pigmentosa with a homozygous PDE6A variant (p.R653X)2019
- Author(s)
  Mizobuchi Kei、Katagiri Satoshi、Hayashi Takaaki、Yoshitake Kazutoshi、Fujinami Kaoru、Kuniyoshi Kazuki、Mishima Reimi、Tsunoda Kazushige、Iwata Takeshi、Nakano Tadashi
- Journal Title
  
  American Journal of Ophthalmology Case Reports
  
  Volume: 13 Pages: 110-115
- DOI
  10.1016/j.ajoc.2018.12.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11434, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16H06269, KAKENHI-PROJECT-16KK0193
[Journal Article] High-Resolution Retinal Imaging Reveals Preserved Cone Photoreceptor Density and Choroidal Thickness in Female Carriers of Choroideremia.2019
- Author(s)
  Suzuki K, Gocho K, Akeo K, Kikuchi S, Kubota D, Katagiri S, Fujinami K, Tsunoda K, Iwata T, Yamaki K, Igarashi T, Nakano T, Takahashi H, Hayashi T, Kameya S.
- Journal Title
  
  Ophthalmic Surg Lasers Imaging Retina.
  
  Volume: 50(2) Issue: 2 Pages: 76-85
- DOI
  10.3928/23258160-20190129-03
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16H06269, KAKENHI-PROJECT-16KK0193, KAKENHI-PROJECT-17K11434
[Journal Article] Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma2018
- Author(s)
  Shiga Yukihiro、Kashiwagi Kenji、Nakazawa Toru、Kubo Michiaki、Japan Glaucoma Society Omics Group (JGS-OG)、NEIGHBORHOOD Consortium
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 27 Issue: 8 Pages: 1486-1496
- DOI
  10.1093/hmg/ddy053
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11478, KAKENHI-PROJECT-17K11482, KAKENHI-PUBLICLY-16H01566, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K08146, KAKENHI-PROJECT-18K09400, KAKENHI-PROJECT-17H03596
[Journal Article] Autosomal dominant retinitis pigmentosa with macular involvement associated with a disease haplotype that included a novel PRPH2 variant (p.Cys250Gly)2018
- Author(s)
  Katagiri Satoshi、Hayashi Takaaki、Mizobuchi Kei、Yoshitake Kazutoshi、Iwata Takeshi、Nakano Tadashi
- Journal Title
  
  Ophthalmic Genetics
  
  Volume: 39 Issue: 3 Pages: 357-365
- DOI
  10.1080/13816810.2018.1459737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11434, KAKENHI-PROJECT-17H06276
[Journal Article] LRRTM4-C538Y novel gene mutation is associated with hereditary macular degeneration with novel dysfunction of ON-type bipolar cells.2018
- Author(s)
  Kawamura Y, Suga A, Fujimaki T, Yoshitake K, Tsunoda K, Murakami A, Iwata T.
- Journal Title
  
  J Hum Genet.
  
  Volume: 63(8) Issue: 8 Pages: 893-900
- DOI
  10.1038/s10038-018-0465-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06276
[Journal Article] KUS121, an ATP regulator, mitigates chorioretinal pathologies in animalmodels of age-related macular degeneration.2018
- Author(s)
  Muraoka, Y., Yoshimura, N., et al.
- Journal Title
  
  Heliyon
  
  Volume: 4 Issue: 5 Pages: e00624-e00624
- DOI
  10.1016/j.heliyon.2018.e00624
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249082, KAKENHI-PROJECT-17K08146, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16K11285, KAKENHI-PROJECT-16H05151
[Journal Article] Early Patterns of Macular Degeneration in ABCA4-Associated Retinopathy.2018
- Author(s)
  Khan KN, Kasilian M, Mahroo OAR, Tanna P, Kalitzeos A, Robson AG, Tsunoda K, Iwata T, Moore AT, Fujinami K, Michaelides M.
- Journal Title
  
  Ophthalmology
  
  Volume: 125(5) Issue: 5 Pages: 735-746
- DOI
  10.1016/j.ophtha.2017.11.020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16H06269, KAKENHI-PROJECT-16KK0193
[Journal Article] Early onset flecked retinal dystrophy associated with new compound heterozygous RPE65 variants.2018
- Author(s)
  Katagiri S, Hosono K, Hayashi T, Kurata K, Mizobuchi K, Matsuura T, Yoshitake K, Iwata T, Nakano T, Hotta Y.
- Journal Title
  
  Mol Vis.
  
  Volume: 24 Pages: 286-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06276
[Journal Article] POSTERIOR STAPHYLOMAS IN EYES WITH RETINITIS PIGMENTOSA WITHOUT HIGH MYOPIA2018
- Author(s)
  Xu Xian、Fang Yuxin、Yokoi Tae、Shinohara Kosei、Hirakata Akito、Iwata Takeshi、Tsunoda Kazushige、Jonas Jost B.、Ohno-Matsui Kyoko
- Journal Title
  
  Retina
  
  Volume: ー Issue: 7 Pages: 1-1
- DOI
  10.1097/iae.0000000000002180
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16920, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-19H03808
[Journal Article] CHANGES OF CONE PHOTORECEPTOR MOSAIC IN AUTOSOMAL RECESSIVE BESTROPHINOPATHY.2018
- Author(s)
  Nakanishi A, Ueno S, Hayashi T, Katagiri S, Ito Y, Kominami T, Fujinami K, Tsunoda K, Iwata T, Terasaki H.
- Journal Title
  
  Retina.
  
  Volume: 218 Issue: 1 Pages: 1782-1787
- DOI
  10.1097/iae.0000000000002363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06276
[Journal Article] Optineurin E50K triggers BDNF deficiency-mediated mitochondrial dysfunction in retinal photoreceptor cell line.2018
- Author(s)
  Shim MS, Kim KY, Noh M, Ko JY, Ahn S, An MA, Iwata T, Perkins GA, Weinreb RN, Ju WK.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 503(4) Issue: 4 Pages: 2690-2697
- DOI
  10.1016/j.bbrc.2018.08.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06276
[Journal Article] Compound heterozygous splice site variants in the SCLT1 gene highlight an additional candidate locus for Senior-Loken syndrome.2018
- Author(s)
  Katagiri S, Hayashi T, Yoshitake K, Murai N, Matsui Z, Kubo H, Satoh H, Matsufuji S, Takamura T, Yokoo T, Omori Y, Furukawa T, Iwata T, Nakano T.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Pages: 16733-16733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06276
[Journal Article] Effect of Timolol on Optineurin Aggregation in Transformed Induced Pluripotent Stem Cells Derived From Patient With Familial Glaucoma.2018
- Author(s)
  Inagaki S, Kawase K, Funato M, Seki J, Kawase C, Ohuchi K, Kameyama T, Ando S, Sato A, Morozumi W, Nakamura S, Shimazawa M, Iejima D, Iwata T, Yamamoto T, Kaneko H, Hara H.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 59(6) Issue: 6 Pages: 2293-2304
- DOI
  10.1167/iovs.17-22975
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-17J10192
[Journal Article] Development of genotyping method for functionally relevant variants of cytochromes P450 in cynomolgus macaques.2018
- Author(s)
  Uno Y, Osada N, Sakurai S, Shimozawa N, Iwata T, Ikeo K, Yamazaki H.
- Journal Title
  
  J Vet Pharmacol Ther.
  
  Volume: 41 Issue: 1
- DOI
  10.1111/jvp.12443
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08146, KAKENHI-PROJECT-17H06276
[Journal Article] Purinergic dysregulation causes hypertensive glaucoma-like optic neuropathy.2017
- Author(s)
  Shinozaki Y, Kashiwagi K, Namekata K, Takeda A, Ohno N, Robaye B, Harada T, Iwata T, *Koizumi S
- Journal Title
  
  JCI Insight
  
  Volume: 2 Issue: 19
- DOI
  10.1172/jci.insight.93456
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08635, KAKENHI-PLANNED-25117003, KAKENHI-PROJECT-17H00738, KAKENHI-PROJECT-15H04999, KAKENHI-PROJECT-16H04669, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16K18390
[Journal Article] Genetic Variant Near PLXDC2 Influences the Risk of Primary Open-angle Glaucoma by Increasing Intraocular Pressure in the Japanese Population.2017
- Author(s)
  Mabuchi F, Mabuchi N, Takamoto M, Sakurada Y, Yoneyama S, Kashiwagi K, Iijima H, Yamagata Z, Aihara M, Iwata T, Araie M. Japan Glaucoma Society Omics Group (JGS-OG).
- Journal Title
  
  J Glaucoma
  
  Volume: 26(11) Issue: 11 Pages: 963-966
- DOI
  10.1097/ijg.0000000000000790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-15K10861
[Journal Article] Additive effects of genetic variants associated with intraocular pressure in primary open-angle glaucoma.2017
- Author(s)
  Mabuchi F, Mabuchi N, Sakurada Y, Yoneyama S, Kashiwagi K, Iijima H, Yamagata Z, Takamoto M, Aihara M, Iwata T, Kawase K, Shiga Y, Nishiguchi KM, Nakazawa T, Ozaki M, Araie M; Japan Glaucoma Society Omics Group (JGS-OG).
- Journal Title
  
  PLoS One.
  
  Volume: 12(8) Issue: 8 Pages: e0183709-e0183709
- DOI
  10.1371/journal.pone.0183709
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-15K10861
[Journal Article] In vivo imaging of a cone mosaic in a patient with achromatopsia associated with a GNAT2 variant.2017
- Author(s)
  Ueno S, Nakanishi A, Kominami T, Ito Y, Hayashi T, Yoshitake K, Kawamura Y, Tsunoda K, Iwata T, Terasaki H.
- Journal Title
  
  Jpn J Ophthalmol
  
  Volume: 61 Issue: 1 Pages: 92-98
- DOI
  10.1007/s10384-016-0484-7
- NAID
  210000179265
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-25462738, KAKENHI-PROJECT-17K11434, KAKENHI-PROJECT-15H04994
[Journal Article] Heterozygous deletion of the OPA1 gene in patients with dominant optic atrophy.2017
- Author(s)
  Hayashi T, Sasano H, Katagiri S, Tsunoda K, Kameya S, Nakazawa M, Iwata T, Tsuneoka H.
- Journal Title
  
  Jpn J Ophthalmol.
  
  Volume: 61 Issue: 5 Pages: 483-488
- DOI
  10.1007/s10384-017-0522-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-26462674
[Journal Article] Missense variants in the X-linked gene PRPS1 cause retinal degeneration in females2017
- Author(s)
  Fiorentino Alessia、Fujinami Kaoru、(Hayashi Takaaki)、Iwata Takeshi、Parker Matthew、Webster Andrew R.、Michaelides Michel、Hardcastle Alison J.、for the 100,000 Genomes Project, the Japan Eye Genetic Consortium and the UK Inherited Retinal Dystrophy Consortium
- Journal Title
  
  Human Mutation
  
  Volume: 39 Issue: 1 Pages: 80-91
- DOI
  10.1002/humu.23349
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11434, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16H06269
[Journal Article] Parafoveal Photoreceptor Abnormalities in Asymptomatic Patients With RP1L1 Mutations in Families With Occult Macular Dystrophy.2017
- Author(s)
  Kato Y, Hanazono G, Fujinami K, Hatase T, Kawamura Y, Iwata T, Miyake Y, Tsunoda K.
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 58(14) Issue: 14 Pages: 6020-6029
- DOI
  10.1167/iovs.17-21969
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16H06269, KAKENHI-PROJECT-26462674
[Journal Article] Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS72017
- Author(s)
  Shiga Yukihiro、Kashiwagi Kenji、Nakazawa Toru、for the Japan Glaucoma Society Omics Group (JGS-OG)
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 12 Pages: e0186678-e0186678
- DOI
  10.1371/journal.pone.0186678
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11478, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16K10488
[Journal Article] Case of cone dystrophy with normal fundus appearance associated with biallelic POC1B variants2017
- Author(s)
  Kominami Azusa、Ueno Shinji、Kominami Taro、Nakanishi Ayami、Ito Yasuki、Fujinami Kaoru、Tsunoda Kazushige、Hayashi Takaaki、Kikuchi Sachiko、Kameya Shuhei、Iwata Takeshi、Terasaki Hiroko
- Journal Title
  
  Ophthalmic Genetics
  
  Volume: 39 Issue: 2 Pages: 255-262
- DOI
  10.1080/13816810.2017.1408846
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11265, KAKENHI-PROJECT-17K11434, KAKENHI-PROJECT-15H04994, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16H06269
[Journal Article] Identification of novel mutations in the LRR-cap domain of C21orf2 in Japanese patients with retinitis pigmentosa and cone-rod dystrophy.2016
- Author(s)
  Suga A, Mizota A, Kato M, Kuniyoshi K, Yoshitake K, Sultan W, Yamazaki M, Shimomura Y, Ikeo K, Tsunoda K, Iwata T.
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 57 Issue: 10 Pages: 4255-4263
- DOI
  10.1167/iovs.16-19450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-15K10914
[Journal Article] Novel RP1L1 variants and genotype-photoreceptor microstructural phenotype associations in cohort of Japanese patients with occult macular dystrophy.2016
- Author(s)
  Fujinami K, Kameya S, Kikuchi S, Ueno S, Kondo M, Hayashi T, Shinoda K, Machida S, Kuniyoshi K, Kawamura Y, Akahori M, Yoshitake K, Katagiri S, Nakanishi A, Sakuramoto H, Ozawa Y, Tsubota K, Yamaki K, Mizota A, Terasaki H, Miyake Y, Iwata T, Tsunoda K.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 57 Issue: 11 Pages: 4837-4846
- DOI
  10.1167/iovs.16-19670
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04994, KAKENHI-PROJECT-16H06269, KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-25462738, KAKENHI-PROJECT-26462683, KAKENHI-PROJECT-15K10903
[Journal Article] Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration.2016
- Author(s)
  Shim MS, Takihara Y, Kim KY, Iwata T, Yue BY, Inatani M, Weinreb R, Perkin GA, Ju WK
- Journal Title
  
  Scientific Reports
  
  Volume: 22 Issue: 1 Pages: 33830-33830
- DOI
  10.1038/srep33830
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05486, KAKENHI-PROJECT-26293377
[Journal Article] Significance of Optineurin Mutations in Glaucoma and Other Diseases.2016
- Author(s)
  Minegishi Y, Nakayama M, Iejima D, Iwata T.
- Journal Title
  
  Prog Ret Eye Res
  
  Volume: 55 Pages: 149-181
- DOI
  10.1016/j.preteyeres.2016.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293377
[Journal Article] Novel mutations in the gene for α-subunit of retinal cone cyclic nucleotide-gated channels in a Japanese patient with congenital achromatopsia.2016
- Author(s)
  Kuniyoshi K, Muraki-Oda S, Ueyama H, Toyoda F, Sakuramoto H, Ogita H, Irifune M, Yamamoto S, Nakao A, Tsunoda K, Iwata T, Ohji M, Shimomura Y.
- Journal Title
  
  Jpn J Ophthalmol
  
  Volume: 60 Issue: 3 Pages: 187-197
- DOI
  10.1007/s10384-016-0424-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460295, KAKENHI-PROJECT-26462674, KAKENHI-PROJECT-25462711, KAKENHI-PROJECT-25462712, KAKENHI-PROJECT-26293377
[Journal Article] Clinical and genetic findings of autosomal recessive bestrophinopathy in Japanese cohort.2016
- Author(s)
  Nakanishi A, Ueno S, Hayashi T, Katagiri S, Kominami T, Ito Y, Gekka T, Masuda Y, Tsuneoka H, Shinoda K, Hirakata A, Inoue M, Fujinami K, Tsunoda K, Iwata T, Terasaki H.
- Journal Title
  
  Am J Ophthalmol.
  
  Volume: 168 Pages: 86-94
- DOI
  10.1016/j.ajo.2016.04.023
- NAID
  120005868242
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04994, KAKENHI-PROJECT-16H06269, KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-25462738
[Journal Article] Electroretinographic evaluations of retinal function before, just after, and after intravitreal injections.2016
- Author(s)
  Yagura K, Shinoda K, Matsumoto S, Terauchi G, Kawashima M, Watanabe E, Matsumoto H, Iwata T, Mizota A, Miyake Y.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 31104-31104
- DOI
  10.1038/srep31104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293377
[Journal Article] RPE65 mutations in two Japanese families with Leber congenital amaurosis.2016
- Author(s)
  Katagiri S, Hayashi T, Yoshitake K, Akahori M, Ikeo K, Gekka T, Tsuneoka H, Iwata T
- Journal Title
  
  Ophthalmic Genetics
  
  Volume: 37 Issue: 2 Pages: 161-169
- DOI
  10.3109/13816810.2014.991931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-25462738
[Journal Article] New truncation mutation of the NR2E3 gene in a Japanese patient with enhanced S-cone syndrome.2016
- Author(s)
  Kuniyoshi K, Hayashi T, Sakuramoto H, Mishima H, Tsuneoka H, Tsunoda K, Iwata T, Shimomura Y.
- Journal Title
  
  Jpn J Ophthalmol
  
  Volume: 60 Issue: 6 Pages: 476-485
- DOI
  10.1007/s10384-016-0470-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-25462738
[Journal Article] CCT2 https://www-kofu.jsps.go.jp/kofu1/images/bt_add_small.gifMutations Evoke Leber Congenital Amaurosis due to Chaperone Complex Instability.2016
- Author(s)
  Minegishi Y, Sheng X, Yoshitake K, Sergeev Y, Iejima D, Shibagaki Y, Monma N, Ikeo K, Furuno M, Zhuang W, Liu Y, Rong W, Hattori A, Iwata T.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 33742-33742
- DOI
  10.1038/srep33742
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-15K08502
[Journal Article] High-Temperature Requirement A Serine Peptidase 1 Gene is Transcriptionally Regulated by Insertion/Deletion Nucleotides Located at the 3 Prime End of Age-Related Maculopathy Susceptibility 2 Gene in Patients with Age-Related Macular Degeneration.2015
- Author(s)
  Iejima D, Itabashi T, Kawamura Y, Noda T, Yuasa S, Fukuda K, Oka C, Iwata T.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 290 Issue: 5 Pages: 2784-2797
- DOI
  10.1074/jbc.m114.593384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-26670408, KAKENHI-PROJECT-26670762
[Journal Article] Congenital Achromatopsia and Macular Atrophy Caused by a Novel Recessive PDE6C Mutation (p.E591K).2015
- Author(s)
  Katagiri S, Hayashi T, Yoshitake K, Sergeev Y, Akahori M, Furuno M, Nishino J, Ikeo K, Tsunoda K, Tsuneoka H, Iwata T.
- Journal Title
  
  Ophthalmic Genet.
  
  Volume: Jun;36(2) Issue: 2 Pages: 137-44
- DOI
  10.3109/13816810.2014.991932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462674, KAKENHI-PROJECT-15K15641, KAKENHI-PROJECT-26293377
[Journal Article] Mutation analysis of BEST1 in Japanese patients with Best’s vitelliform macular dystrophy2015
- Author(s)
  Katagiri S，Hayashi T，Ohkuma Y，Sekiryu T，Takeuchi T，Gekka T，et al.
- Journal Title
  
  Br J Ophthalmol
  
  Volume: 99 Issue: 11 Pages: 1577-1582
- DOI
  10.1136/bjophthalmol-2015-306830
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462738, KAKENHI-PROJECT-26462683, KAKENHI-PROJECT-25462724, KAKENHI-PROJECT-15K15641, KAKENHI-PROJECT-26293377
[Journal Article] Association of Retinal Artery and Other Inner Retinal Structures With Distribution of Tapetal-like Reflex in Oguchi's Disease.2015
- Author(s)
  Kato Y, Tsunoda K, Fujinami K, Iwata T, Saga M, Oguchi Y.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: Apr;56(4) Issue: 4 Pages: 2162-72
- DOI
  10.1167/iovs.14-16198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462674, KAKENHI-PROJECT-15K15641, KAKENHI-PROJECT-26293377
[Journal Article] Novel nonsense and splice site mutations in CRB1 gene in two Japanese patients with early-onset retinal dystrophy Documenta Ophthalmologica.2015
- Author(s)
  Kuniyoshi K, Ikeo K, Sakuramoto H, Furuno M, Yoshitake K, Hatsukawa Y, Nakao A, Kusaka S, Shimomura Y, Iwata T.
- Journal Title
  
  Documenta Ophthalmologica
  
  Volume: 130 Issue: 1 Pages: 49-55
- DOI
  10.1007/s10633-014-9464-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-26462674, KAKENHI-PROJECT-26670762
[Journal Article] Reduced rod electroretinograms in carrier parents of two Japanese siblings with autosomal recessive retinitis pigmentosa associated with PDE6B gene mutations.2015
- Author(s)
  Kuniyoshi K, Sakuramoto H, Yoshitake K, Ikeo K, Furuno M, Tsunoda K, Kusaka S, Shimomura Y, Iwata T.
- Journal Title
  
  Doc Ophthalmol.
  
  Volume: Aug;131(1) Issue: 1 Pages: 71-9
- DOI
  10.1007/s10633-015-9497-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462674, KAKENHI-PROJECT-15K15641, KAKENHI-PROJECT-26293377
[Journal Article] HTRA1 Overexpression Induces the Exudative Form of Age-related Macular Degeneration.2015
- Author(s)
  Iejima D, Nakayama M, Iwata T
- Journal Title
  
  Nova Science Publishers
  
  Volume: 10 Pages: 193-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15641
[Journal Article] Pathologic Changes of Cone Photoreceptors in Eyes With Occult Macular Dystrophy.2015
- Author(s)
  Nakanishi A, Ueno S, Kawano K, Ito Y, Kominami T, Yasuda S, Kondo M, Tsunoda K, Iwata T, Terasaki H.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: Nov;56(12) Issue: 12 Pages: 7243-9
- DOI
  10.1167/iovs.15-16742
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462674, KAKENHI-PROJECT-26462683, KAKENHI-PROJECT-26861444, KAKENHI-PROJECT-15H04994, KAKENHI-PROJECT-25462709, KAKENHI-PROJECT-25462710, KAKENHI-PROJECT-15K15641, KAKENHI-PROJECT-26293377
[Journal Article] HTRA1 Overexpression Induces the Exudative Form of Age-Related Macular Degeneration. Age-Related Macular Degeneration: Prevalence, Risk Factors and Clinical Management.2015
- Author(s)
  Iejima D, Nakayama M, Iwata T.
- Journal Title
  
  J Stem Cells.
  
  Volume: 10 Pages: 193-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293377
[Journal Article] Author Response: Postnatal Overexpression of the Human ARMS2 Gene Does Not Induce Abnormalities in Retina and Choroid in Transgenic Mouse Models.2015
- Author(s)
  Iwata T.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 56 Issue: 2 Pages: 1389-1389
- DOI
  10.1167/iovs.14-16174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15641, KAKENHI-PROJECT-26293377
[Journal Article] Novel C8orf37 mutations in patients with early-onset retinal dystrophy, macular atrophy, cataracts, and high myopia.2014
- Author(s)
  Katagiri S, Hayashi T, Yoshitake K, Akahori M, Ikeo K, Gekka T, Tsuneoka H, Iwata T.
- Journal Title
  
  Ophthalmic Genetics
  
  Volume: 12 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293377
[Journal Article] Binocular interaction of visually evoked cortical potentials elicited by dichoptic binocular stimulation.2014
- Author(s)
  Matsumoto CS, Nakagomi R, Matsumoto H, Minoda H, Shinoda K, Iwata T, Mizota A.
- Journal Title
  
  J Vis.
  
  Volume: 14(11) Issue: 11 Pages: 1-9
- DOI
  10.1167/14.11.4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462735, KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-26670762
[Journal Article] Lack of association of LOXL1 gene variants in Japanese patients with central retinal vein occlusion without clinically detectable pseudoexfoliation material deposits.2014
- Author(s)
  Tanito M, Hara K, Akahori M, Harata A, Itabashi T, Takai Y, Kaidzu S, Ohira A, Iwata T.
- Journal Title
  
  Acta Ophthalmologica
  
  Volume: 印刷確定 Issue: 3
- DOI
  10.1111/aos.12534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462744, KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-26670762
[Journal Article] RHO mutations (p.W126L and p.A346P) in two Japanese families with autosomal dominant retinitis pigmentosa2014
- Author(s)
  Katagiri S, Hayashi T, Akahori M, Itabashi T, Nishio J, Yoshitake K, Furuno M, Ikeo K, Okada T, Tsuneoka H, Iwata T
- Journal Title
  
  J Ophthalmol
  
  Volume: 2014 Pages: 210947-210947
- DOI
  10.1155/2014/210947
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462738, KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-26670762
[Journal Article] Heterozygote Wdr36-deficient mice do not develop glaucoma.2014
- Author(s)
  Gallenberger M, Kroeber M, Koch M, März L, Fuchshofer R, Iwata T, Braunger BM, Tamm ER.
- Journal Title
  
  Experimental Eye Research
  
  Volume: 128 Pages: 83-91
- DOI
  10.1016/j.exer.2014.09.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-26670762
[Journal Article] Plasma Proteome Analysis On Cynomolgus Monkey (Macaca fascicularis) Pedigrees With Early Onset Drusen Formation.2014
- Author(s)
  Kobayashi H, Okamoto H, Murakami A, Iwata T
- Journal Title
  
  Journal of Experimental Animals
  
  Volume: 印刷中
- NAID
  130004677825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Retinal angiomatous proliferation associated with risk alleles of ARMS2/HTRA1 gene polymorphisms in Japanese patients.2014
- Author(s)
  Ohkuma Y, Hayashi T, Sakai T, Watanabe A, Yamada H, Akahori M, Itabashi T, Iwata T, Noda T, Tsuneoka H
- Journal Title
  
  Journal of Clinical Ophthalmology
  
  Volume: 8 Pages: 143-148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] RPE65 mutations in two Japanese families with Leber congenital amaurosis.2014
- Author(s)
  Katagiri S, Hayashi T, Yoshitake K, Akahori M, Ikeo K, Gekka T, Tsuneoka H, Iwata T.
- Journal Title
  
  Ophthalmic Genetics
  
  Volume: 12 Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670762
[Journal Article] Longitudinal clinical course of three Japanese patients with Leber congenital amaurosis/severe early childhood onset retinal dystrophy with RDH12 mutation.2014
- Author(s)
  Kuniyoshi K, Sakuramoto H, Yoshitake K, Abe K, Ikeo K, Furuno M, Tsunoda K, Kusaka S, Shimomura Y, Iwata T
- Journal Title
  
  Documenta Ophthalmologica
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Overexpression of HtrA1 and exposure to mainstream cigarette smoke leads to choroidal neovascularization and subretinal deposits in aged mice2014
- Author(s)
  Mao Nakayama, Daisuke Iejima, Masakazu Akahori, Junzo Kamei, Asako Goto, Takeshi Iwata
- Journal Title
  
  IOVS (investigative ophthalmology＆visual science)
  
  Volume: 55 Issue: 10 Pages: 6514-6523
- DOI
  10.1167/iovs.14-14453
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592664, KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-26670762
[Journal Article] RPE65 mutations in two Japanese families with Leber congenital amaurosis.2014
- Author(s)
  Katagiri S, Hayashi T, Yoshitake K, Akahori M, Ikeo K, Gekka T, Tsuneoka H, Iwata T.
- Journal Title
  
  Ophthalmic Genetics
  
  Volume: 12 Pages: 1-9
- Data Source
  KAKENHI-PROJECT-26293377
[Journal Article] Pattern visual evoked potentials elicited by organic electroluminescence screen.2014
- Author(s)
  Matsumoto CS, Shinoda K, Matsumoto H, Funada H, Sasaki K, Minoda H, Iwata T, Mizota A.
- Journal Title
  
  Biomed Res Int.
  
  Volume: 606951 Pages: 1-6
- DOI
  10.1155/2014/606951
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462735, KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-26670762
[Journal Article] What monitor can replace cathode ray tube for visual stimulation to elicit multifocal electroretinograms?2014
- Author(s)
  Matsumoto CS, Shinoda K, Matsumoto H, Seki K, Nagasaka E, Iwata T, Mizota A
- Journal Title
  
  Journal of Vision
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Autosomal recessive cone-rod dystrophy associated with compound heterozygous mutations in the EYS gene.2014
- Author(s)
  Katagiri S, Akahori M, Hayashi T, Yoshitake K, Gekka T, Ideo K, Tsuneoka H, Iwata T
- Journal Title
  
  Documenta Ophthalmologica
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Novel C8orf37 mutations in patients with early-onset retinal dystrophy, macular atrophy, cataracts, and high myopia.2014
- Author(s)
  Katagiri S, Hayashi T, Yoshitake K, Akahori M, Ikeo K, Gekka T, Tsuneoka H, Iwata T.
- Journal Title
  
  Ophthalmic Genetics
  
  Volume: 12 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670762
[Journal Article] Whole exome analysis identifies frequent CNGA1 mutations in Japanese population with autosomal recessive retinitis pigmentosa2014
- Author(s)
  Katagiri S, Akahori M, Sergeev Y, Yoshitake K, Ikeo K, Furuno M, Hayashi T, Kondo M, Ueno S, Tsunoda K, Shinoda K, Kuniyoshi K, Tsurusaki Y, Matsumoto N, Tsuneoka H, Iwata T.
- Journal Title
  
  Plos One
  
  Volume: 9（9） Issue: 9 Pages: e108721-e108721
- DOI
  10.1371/journal.pone.0108721
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118007, KAKENHI-PROJECT-24249019, KAKENHI-PROJECT-25462744, KAKENHI-PROJECT-25860915, KAKENHI-PROJECT-26293377, KAKENHI-PROJECT-26462674, KAKENHI-PROJECT-26670762
[Journal Article] Long-term observation over ten years of four cases of cone dystrophy with supernormal rod electroretinogram2013
- Author(s)
  Nakamura N, Tsunoda K, Fujinami K, Shinoda K, Tomita K, Hatase T, Usui T, Akahori M, Iwata T, Miyake Y
- Journal Title
  
  Nihon Ganka Gakkai Zasshi
  
  Volume: 117 Pages: 629-40
- NAID
  10031189436
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Whole-exome sequencing identifies a novel ALMS1 mutation (p.Q2051X) in two Japanese brothers with Alstrom Syndrome.2013
- Author(s)
  Katagiri S, Yoshitake K, Akahori M, Hayashi T, Furuno M, Nishino J, Ikeo K, Tsuneoka H, Iwata T
- Journal Title
  
  Molecular Vision
  
  Volume: 19 Pages: 2393-2406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Two siblings with late-onset cone-rod dystrophy and no visible macular degeneration.2013
- Author(s)
  Sakuramoto H, Kuniyoshi K, Tsunoda K, Akahori M, Iwata T, Shimomura Y
- Journal Title
  
  Journal of Clinical Ophthalmology
  
  Volume: 7 Pages: 1703-1711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] 日米の眼研究の架け橋　Jin H. Kinoshita先生を偲んで　（編集：堀田喜裕）2013
- Author(s)
  岩田岳（編集：堀田喜裕）
- Journal Title
  
  あたらしい眼科
  
  Volume: 30 Pages: 1417-1418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma.2013
- Author(s)
  Minegishi Y, Iejima D, Kobayashi H, Chi Z-L, Kawase K, Yamamoto T, Seki T, Yuasa S, Fukuda K, Iwata T
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 22 Pages: 3559-3567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Two siblings with late-onset cone-rod dystrophy and no visible macular degeneration2013
- Author(s)
  Sakuramoto H, Kuniyoshi K, Tsunoda K, Akahori M, Iwata T, Shimomura Y
- Journal Title
  
  Journal of Clinical Ophthalmology
  
  Volume: 7 Pages: 1703-11
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Molecular characteristics of four Japanese cases with KCNV2 retinopathy : report of novel disease-causing variants2013
- Author(s)
  Fujinami K, Tsunoda K, Nakamura N, Kato Y, Noda T, Shinoda K, Tomita K, Hatase T, Usui T, Akahori M, Itabashi T, Iwata T, Ozawa Y, Tsubota K, Miyake Y.
- Journal Title
  
  Molecular Vision
  
  Volume: 19 Pages: 1580-90
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma2013
- Author(s)
  Minegishi Y, Iejima D, Kobayashi H, Chi Z-L, Kawase K, Yamamoto T, Seki T, Yuasa S, Fukuda K, Iwata T
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 22 Pages: 3559-67
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Molecular characteristics of four Japanese cases with KCNV2 retinopathy: report of novel disease-causing variants.2013
- Author(s)
  Fujinami K, Tsunoda K, Nakamura N, Kato Y, Noda T, Shinoda K, Tomita K, Hatase T, Usui T, Akahori M, Itabashi T, Iwata T, Ozawa Y, Tsubota K, Miyake Y
- Journal Title
  
  Molecular Vision
  
  Volume: 19 Pages: 1580-1590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Whole-exome sequencing identifies a novel ALMS1 mutation (p.Q2051X) in two Japanese brothers with Alstrom Syndrome2013
- Author(s)
  Katagiri S, Yoshitake K, Akahori M, Hayashi T, Furuno M, Nishino J, Ikeo K, Tsuneoka H, Iwata T
- Journal Title
  
  Molecular Vision
  
  Volume: 19 Pages: 2393-406
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] [Long-term observation over ten years of four cases of cone dystrophy with supernormal rod electroretinogram].2013
- Author(s)
  Nakamura N, Tsunoda K, Fujinami K, Shinoda K, Tomita K, Hatase T, Usui T, Akahori M, Iwata T, Miyake Y
- Journal Title
  
  Nihon Ganka Gakkai Zasshi
  
  Volume: 117 Pages: 629-640
- NAID
  10031189436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670742
[Journal Article] Processing of optineurin in neuronal cells2011
- Author(s)
  Shen X, Ying H, Qiu Y, Park J-S, Shyam R, Chi Z-L, Iwata T, Yue BYJT.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 286 Pages: 3618-29
- Data Source
  KAKENHI-PROJECT-21390471
[Journal Article] Analysis of LOXL1 gene variants in Japanese patients with branch retinal vein occlusion2011
- Author(s)
  Hara K, Akahori M, Tanito M, Kaidzu S, Ohira A, Iwata T.
- Journal Title
  
  Molecular Vision
  
  Volume: 17 Pages: 3309-13
- Data Source
  KAKENHI-PROJECT-21390471
[Journal Article] Mutant WDR36 directly affects axon growth of retinal ganglion cells leading to progressive retinal degeneration in mice2010
- Author(s)
  Chi ZL, Yasumoto F, Sergeev Y, Minami M, Obazawa M, Kimura I, Takada Y, Iwata T
- Journal Title
  
  Hum Mol Genet
  
  Volume: 19 Pages: 3806-3815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592253
[Journal Article] Mutant WDR36 directly affects axon growth of retinal ganglion cells leading to progressive retinal degeneration in mice.2010
- Author(s)
  Chi ZL, Yasumoto F, Sergeev Y, Minami M, Obazawa M, Kimura I, Takada Y, Iwata T
- Journal Title
  
  Hum Mol Genet
  
  Volume: 19 Issue: 19 Pages: 3806-3815
- DOI
  10.1093/hmg/ddq299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592253, KAKENHI-PROJECT-22700450
[Journal Article] Mutant WDR36 directly affects axon growth of retinal ganglion cells leading to progressive retinal degeneration in mice2010
- Author(s)
  Chi Z-L, Yasumoto F, Sergeev Y, Minami M, Obazawa M, Kimura I, Takada Y, and Iwata T.
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 19 Pages: 3806-3815
- Data Source
  KAKENHI-PROJECT-21390471
[Journal Article] Vav2 and Vav3 as candidate disease gene for spontaneous glaucoma in mice and human2010
- Author(s)
  Fujikawa K, Iwata T, Inoue K, Akahori M, Kadotani H, Fukaya M, Watanabe M, Chang Q, Barnett EM, and Swat W.
- Journal Title
  
  PLOS One
  
  Volume: 5
- NAID
  120001896679
- Data Source
  KAKENHI-PROJECT-21390471
[Journal Article] Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice2010
- Author(s)
  Chi Z-L, Akahori, A, Obazawa M, Minami M, Noda T, Nakaya N, Tomarev S, Kawase K, Yamamoto T, Noda S, Sasaoka M, Shimazaki A, Takada Y, and Iwata T.
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 19 Pages: 2605-2615
- Data Source
  KAKENHI-PROJECT-21390471
[Journal Article] 緑内障遺伝子改変動物の基礎2009
- Author(s)
  岩田岳
- Journal Title
  
  眼薬理
- NAID
  10027119510
- Data Source
  KAKENHI-PROJECT-21390471
[Journal Article] LOXL1 variants in elderly Japanese patients with exfoliation syndrome/glaucoma, primary open angle glaucoma, normal tension glaucoma, and cataract2008
- Author(s)
  Tanito M, Minami M, Akahori M, Kaidzu S, Takai Y, Ohira A, Iwata T. (Tanito, Minami, Akahoriは同程度に貢献)
- Journal Title
  
  Molecular Vision 14
  
  Pages: 1898-1905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592069
[Journal Article] HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration.2007
- Author(s)
  Yoshida T, DeWan A, Zhang H, Sakamoto R, Okamato H, Minami M, Obazawa M, Mizota A, Tanaka M, Saito Y, Takagi I, Hoh J, Iwata T.
- Journal Title
  
  Molesular Vision(perr-reviewed journal) 13
  
  Pages: 545-548
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591948
[Journal Article] HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration.2007
- Author(s)
  Yoshida T, DeWan A, Zhang H, Sakamoto R, Okamoto H, Minami M, Obazawa M, Mizota A, Tanaka M, Saito Y, Takagi I, Hoh J, Iwata T.
- Journal Title
  
  Molecular Vision 13
  
  Pages: 545-548
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591948
[Journal Article] HTRAl promoter polymorphism predisposes Japanese to age-related macular degeneration.2007
- Author(s)
  Yoshida T, DeWan A, Zhang H, Sakamoto R, Oka moto H, Minami M, Obazawa M, Mizota A, Tanaka M, Saito Y, Takagi I, Hoh J, Iwata T.
- Journal Title
  
  Molecular Vision 13
  
  Pages: 545-548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591948
[Journal Article] HIRAI promoter polymorphism predisposes Japanese to age-related macular degeneration.2006
- Author(s)
  Yoshida T, DeWan A, Zhang H, Sakamoto R, Okamoto H, Minami M, Obazawa M, Mizota A, Tanaka M, Saito Y, Takagi I, Hoh J, Iwata T.
- Journal Title
  
  Molecular Vision 13
  
  Pages: 545-548
- Data Source
  KAKENHI-PROJECT-18591948
[Journal Article] Complement factor H polymorphisms in Japanese population with age-related macular degeneration2006
- Author(s)
  Okamoto H, Umeda S, Obazawa M, Minami M, Noda T, Mizota A, Honda M, Tanaka M, Koyama R, Takagi I, Sakamoto Y, Saito Y, Miyake Y, Iwata T.
- Journal Title
  
  Molecular Vision 6
  
  Pages: 156-158
- Data Source
  KAKENHI-PROJECT-18591948
[Journal Article] Early onset macular degeneration with drusen in a cynomolgus monkey (Macaca fascicularis) pedigree caused by a novel gene mutation.2005
- Author(s)
  Umeda S, Iwata T et al.
- Journal Title
  
  Invest Ophthal Vis Sci 46
  
  Pages: 683-691
- Data Source
  KAKENHI-PROJECT-16591779
[Journal Article] Novel MYOC Gene Mutation, Phe369Leu, in Japanese Patients with Primary Open-Angle Glaucoma Detected by Denaturing High-Performance Liquid Chromatography.2004
- Author(s)
  Ishikawa K, Iwata T et al.
- Journal Title
  
  J Glaucoma 13
  
  Pages: 466-471
- Data Source
  KAKENHI-PROJECT-16591779
[Journal Article] Variants in Optineurin Gene and their Association with Tumor Necrosis Factor-alpha (-857C>T) Polymorphisms in Japanese Patients with Glaucoma.2004
- Author(s)
  Funayama T, Iwata T et al.
- Journal Title
  
  Invest Ophthal Vis Sci 45
  
  Pages: 4359-4367
- Data Source
  KAKENHI-PROJECT-16591779
[Journal Article] Purification, Molecular Cloning, and Expression of a Novel Growth Promotive Factor for Retinal Pigment Epithelial Cells. REF-1/TFPI-22004
- Author(s)
  Tanaka Y, Iwata T et al.
- Journal Title
  
  Invest Ophthal Vis Sci 45
  
  Pages: 245-252
- Data Source
  KAKENHI-PROJECT-16591779
[Journal Article] The MICA5.1 allele is not associated with susceptibility to effects of ultraviolet-B radiation on induction of contact hypersensitivity.2004
- Author(s)
  Niizeki H, Iwata T et al.
- Journal Title
  
  J Dermatol Sci 35
  
  Pages: 221-223
- NAID
  10016184929
- Data Source
  KAKENHI-PROJECT-16591779
[Journal Article] Comparable Analysis of Porcine Optineurin and Myocilin Expression in Trabecular Meshwork Cells and Astrocytes from Optic Nerve Head.2004
- Author(s)
  Obazawa M, Iwata T et al.
- Journal Title
  
  Invest Ophthal Vis Sci 45
  
  Pages: 2652-2659
- Data Source
  KAKENHI-PROJECT-16591779
[Patent] 加齢黄斑変性の診断マーカー、診断キット、診断補助方法、及び、発症リスク判定方法2018
- Inventor(s)
  岩田岳、野田徹、家島大輔
- Industrial Property Rights Holder
  岩田岳、野田徹、家島大輔
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H06276
[Patent] 細胞増殖を伴う糖尿病合併症の検査のための方法、組成物およびキット2009
- Inventor(s)
  岩田岳
- Industrial Property Rights Holder
  東京医療センター
- Industrial Property Number
  2008-257691
- Filing Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390471
[Patent] 老化、および血管障害を伴う疾患の検定のための組成物、キットおよび方法2009
- Inventor(s)
  岩田岳
- Industrial Property Rights Holder
  東京医療センター
- Industrial Property Number
  2008-092245
- Filing Date
  2009-03-31
- Data Source
  KAKENHI-PROJECT-21390471
[Patent] 神経障害の検定のための組成物、キットおよび方法2009
- Inventor(s)
  岩田岳
- Industrial Property Rights Holder
  東京医療センター
- Industrial Property Number
  2008-091522
- Filing Date
  2009-03-31
- Data Source
  KAKENHI-PROJECT-21390471
[Patent] 代謝障害を伴う疾患の検定のための組成物、キットおよび方法2009
- Inventor(s)
  岩田岳
- Industrial Property Rights Holder
  東京医療センター
- Industrial Property Number
  2008-092021
- Filing Date
  2009-03-31
- Data Source
  KAKENHI-PROJECT-21390471
[Patent] 糖尿病性末梢血管障害の検査のための方法、組成物およびキット2009
- Inventor(s)
  岩田岳
- Industrial Property Rights Holder
  東京医療センター
- Industrial Property Number
  2008-257430
- Filing Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390471
[Patent] コラーゲン線維の萎縮による組織障害の検査のための方法、組成物及びキット2009
- Inventor(s)
  岩田岳
- Industrial Property Rights Holder
  東京医療センター
- Industrial Property Number
  2008-257469
- Filing Date
  2009-10-01
- Overseas
- Data Source
  KAKENHI-PROJECT-21390471
[Patent] コラーゲン線維の萎縮による組織障害の検査のための方法、組成物及びキット2008
- Inventor(s)
  岩田岳
- Industrial Property Rights Holder
  東京医療センター
- Industrial Property Number
  2008-257469
- Filing Date
  2008-10-02
- Data Source
  KAKENHI-PROJECT-21390471
[Patent] 代謝障害を伴う疾患の検定のための組成物、キットおよび方法2008
- Inventor(s)
  岩田岳
- Industrial Property Rights Holder
  国立病院機構東京医療センター
- Filing Date
  2008
- Data Source
  KAKENHI-PROJECT-21390471
[Patent] 緑内障のリスクの予測方法2008
- Inventor(s)
  岩田岳
- Industrial Property Rights Holder
  国立病院機構東京医療センター
- Filing Date
  2008
- Data Source
  KAKENHI-PROJECT-21390471
[Patent] 神経障害の検定のための組成物、キットおよび方法2008
- Inventor(s)
  岩田岳
- Industrial Property Rights Holder
  国立病院機構東京医療センター
- Filing Date
  2008
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] Malonyl-CoA-Acyl Carrier Protein Transacylase Provoke Autosomal Recessive Optic Neuropathy2020
- Author(s)
  Takeshi Iwata, Huiping Li, Shiqin Yuan, Yuriko Minegishi, Akiko Suga, Kazutoshi Yoshitake, Xunlun Sheng, Jianping Ye, Stuart Smith, Gabor Bunkoczi, Megumi Yamamoto.
- Organizer
  The Association for Research in Vision and Ophthalmology (ARVO) Virtual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] 遺伝性網膜疾患の症例・ゲノム情報の収集：日本から世界への展開2020
- Author(s)
  岩田岳
- Organizer
  第74回バーチャル・国立病院総合医学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Novel Mutations in Malonyl-CoA-Acyl Carrier Protein Transacylase Provoke Autosomal Recessive Optic Neuropathy2020
- Author(s)
  Takeshi Iwata, Huiping Li, Shiqin Yuan, Yuriko Minegishi, Akiko Suga, Kazutoshi Yoshitake, Xunlun Sheng, Jianping Ye, Stuart Smith, Gabor Bunkoczi, Megumi Yamamoto.
- Organizer
  American Society for Human Genetics (ASHG) Virtual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] GEGC research plans in Africa and the Middle East.2020
- Author(s)
  Takeshi Iwata.
- Organizer
  World Ophthalmology Congress (WOC) Virtual Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] シンポジウム5 網膜視神経細胞死のメカニズム：ゲノム解析から発症分子機序の解明2020
- Author(s)
  岩田岳
- Organizer
  第31回バーチャル日本緑内障学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Establishment of Asian Eye Genetics Consortium (AEGC, http://asiangenetics.) by 20 countries2018
- Author(s)
  Takeshi Iwata
- Organizer
  XIVth Biennial SAARC Academy of Opththalmology (SAO) Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] [KEY NOTE TALK]Neuroprotection of Optineurin E50K Knok-in Mice with Normal Tension Glaucoma by TBK1 Inhibitor Amlexanox2018
- Author(s)
  Takeshi Iwata
- Organizer
  ARVO India 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] ARMS2/HTRA1 as Potential Theraperutic Target for Age-related Macular Degeneration2018
- Author(s)
  Takeshi Iwata
- Organizer
  International Society for Eye Research 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] HTRA1 as Potential Therapeutic Target for Age-Related Macular Degeneration.2018
- Author(s)
  Takeshi Iwata
- Organizer
  APAO 2018
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Asian Eye Genetics Consortium.2018
- Author(s)
  Takeshi Iwata
- Organizer
  APAO 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Age-related Macular Degeneration2018
- Author(s)
  Takeshi Iwata
- Organizer
  ARVO India
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Update on the Global Eye Genetics Consortium2018
- Author(s)
  Takeshi Iwata
- Organizer
  XIVth Biennial SAARC Academy of Opththalmology (SAO) Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Establishment of the Asian Eye Genetics Consortium to Study Eye Diseases Associated with Gene Sequence. Introduction of Network and Finding of Novel Genes Responsible for LCA, Optic Neuropathy, and Others.2018
- Author(s)
  Takeshi Iwata
- Organizer
  APAO 2018
- Invited
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] 緑内障遺伝子解析から個別医療へ2018
- Author(s)
  岩田岳
- Organizer
  第29回日本緑内障学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Asia and the Global Eye Genetics Consortium: A research based consortium for advances in vision research2018
- Author(s)
  Takeshi Iwata
- Organizer
  he Founding Conference of the Global Eye Genetics Consortium （GEGC）Chinese Branch & The First Academic Confernce on Eye Genetics Disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Identifying novel genes for hereditary retinal diseases and development of drug for glaucoma from the Japan Eye Genetics Consortium2018
- Author(s)
  Takeshi Iwata
- Organizer
  XIVth Biennial SAARC Academy of Opththalmology (SAO) Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Mechanisms of transcriptional regulation by ARMS2/HTRA1 haplotype as risk factor for age-rerated macular degeneration2018
- Author(s)
  Takeshi Iwata
- Organizer
  International Symposium on Retinal Degeneration 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Global Eye Genetics Consortium (GEGC)2018
- Author(s)
  Takeshi Iwata
- Organizer
  All India Ophthalmological Society Conference 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Optimized Homology Directed Repair for Treatment of Inherited Retinal Diseases Using the CRISPR/Cas9 System.<Poster Session>2018
- Author(s)
  Takeshi Iwata
- Organizer
  HGM 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Establishment and Activity of the Asian Eye Genetics Consortium (AEGC).<Poster Session>2018
- Author(s)
  Takeshi Iwata
- Organizer
  HGM 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Global Eye Genetics Consortium (GEGC)2018
- Author(s)
  Takeshi Iwata
- Organizer
  Asia-Pacific Academy of Ophthalmology Congress 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Molecular characteristic of macular suscepribility for dysfunction and degeneration2018
- Author(s)
  Takeshi Iwata
- Organizer
  International Society for Eye Research 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] 座長：基礎研究から病態を捉える2018
- Author(s)
  岩田岳
- Organizer
  Retinal Research Forum 2018
- Invited
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Animal Models for Eye Diseases2018
- Author(s)
  Takeshi Iwata
- Organizer
  ARVO India
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Asian Eye Genetics Consortium: International collaboration to accelerate identification of novel disease-causing genes.2017
- Author(s)
  Takeshi Iwata
- Organizer
  ARVO-Asia 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] 新規緑内障遺伝子や発症機序からの薬剤開発2017
- Author(s)
  岩田　岳
- Organizer
  第121回日本眼科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Chracterization and Whole-Genome Analysis of Cynomolgus Monkeys with Hereditary Macular Drusen.2017
- Author(s)
  Akiko Suga, Mao Nakayama, Zai-Long Chi, Atsushi Mizota, Nobuhiro Shimozawa, Kazutoshi Yoshitake, Takeshi Iwata
- Organizer
  ARVO 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10914
[Presentation] 全エクソーム解析による遺伝性網膜疾患の病因・病態機序の解明2017
- Author(s)
  岩田　岳
- Organizer
  第71回日本臨床眼科学会
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Coordinated Strategy for Genetic Eye Research in Asia and the Pasific.2017
- Author(s)
  Takeshi Iwata
- Organizer
  ARVO 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] International network in eye disease-the Asian Eye Genetics Consortium　(AEGC). <Poster Session>2017
- Author(s)
  Takeshi Iwata
- Organizer
  ARVO 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] International Collaborations to Identify Novel Genes Responsible for Hereditary Retinal Diseases in the Asia Population.2017
- Author(s)
  Takeshi Iwata
- Organizer
  APAO Conress2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] 遺伝性網脈絡膜疾患の網羅的解析：オールジャパンからアジアへの展開2017
- Author(s)
  岩田　岳
- Organizer
  バイエルレチナアワード、第121回日本眼科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06276
[Presentation] Genetic factors and molecular mechanisms of early stage AMD : CNV mouse and drusen primate models.2016
- Author(s)
  Iwata T.
- Organizer
  XVⅡ International Symposium of Retinal Degeneration 2016
- Place of Presentation
  Kyoto International Conference Center
- Year and Date
  2016-09-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293377
[Presentation] Characterization and whole genome analysis of cynomolgus monkeys with hereditary macular druse.2016
- Author(s)
  Suga A, Nakayama M, Z.-L. Chi, Himozawa Y, Yoshitake T, Iwata T.
- Organizer
  XXⅡ Biennial Meeting of the International Society for Eye Research
- Place of Presentation
  Keio Plaza Hotel Tokyo
- Year and Date
  2016-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293377
[Presentation] Characterization and whole genome analysis of cynomolgus monkeys with hereditary macular drusen2016
- Author(s)
  Akiko Suga, Mao Nakayama, Zai-Long Chi, Nobuhiro Shimozawa, Kazutoshi Yoshitake, Takeshi Iwata
- Organizer
  XXII Biennial Meeting of the International Society for Eye Research
- Place of Presentation
  京王プラザホテル
- Year and Date
  2016-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10914
[Presentation] Identification of novel mutations in C21ORF2 from Japanese patients with early-onset retinitis pigmentosa.2016
- Author(s)
  Akiko Suga, Mitsuhiro Kato, Kazutoshi Yoshitake, Astushi Mizota, Kazuho Ikeo, Takeshi Iwata
- Organizer
  13th International Congress of Human Genetics (ICHG2016)
- Place of Presentation
  京都国際会館
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10914
[Presentation] 網膜色素変性と錐体杆体ジストロフィーそれぞれの患者から見つかった繊毛遺伝子C21orf2の新規変異2016
- Author(s)
  須賀晶子、溝田淳、加藤光広、国吉一樹、吉武和敏、William Sultan、山崎正志、下村嘉一、池尾一穂、角田和繁、岩田岳
- Organizer
  第9回　Retina Research Meeting (RRM)
- Place of Presentation
  JPタワー　ホール＆カンファレンス
- Data Source
  KAKENHI-PROJECT-15K10914
[Presentation] 加齢黄斑変性感受性遺伝子HtrA1のトランスジェニックマウスの病態と習慣因子(喫煙)の影響2014
- Author(s)
  中山真央、家島大輔、亀井淳三、岩田岳
- Organizer
  Retina Research Meeting (RRM)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] 滲出型加齢黄斑変性感受性遺伝子 ARMS2-HtrA1のプロモーターの解析2014
- Author(s)
  家島大輔,板橋剛,川村雄一,野田徹,湯浅慎介,岡千緒,福田恵一,岩田岳
- Organizer
  Retina Research Meeting (RRM)東京
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] H A novel CYP4V2 mutation (S121Y) in choroideremia like phenotype2013
- Author(s)
  Katagiri S, Hayashi T, Gekka T, Yamada H, Iwata T, Tsuneoka
- Organizer
  The 8th APVRS Congress &第52回日本網膜硝子体学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] Overexpression of HtrA1 and Smoking Evokes Choroidal Neovascularization and Retinal Deposit in Aged Mice2013
- Author(s)
  Nakayama M, Iejima D, Akahori M, Kamei J, Iwata T.
- Organizer
  ARVO Annual Meeting 2013
- Place of Presentation
  Seattle, WA, USA.
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] Alstrom症候群の兄弟例2013
- Author(s)
  片桐聡,林孝彰,月花環,伊藤直子,岩田岳,常岡寛
- Organizer
  第61回日本臨床視覚電気生理学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] Characterization of early-onset drusen forming cynomolgus monkeys2013
- Author(s)
  Iwata T.
- Organizer
  Asia ARVO 2013
- Place of Presentation
  New Delhi,India(2013年10月第6回Retina Research Meeting (RRM)主催(世話人:村上晶、岩田岳、溝田淳、渡辺すみ子)JPタワー東京)
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open angle glaucoma2013
- Author(s)
  Iwata T.
- Organizer
  ISER Sarasota Symposium
- Place of Presentation
  Sarasota, Florida, USA( University of Florida Gainesville, Department of Ophthalmology )
- Invited
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] 緑内障原因遺伝子オプチニューリンと E50K変異によるタンパクの不溶化と病態発症との関連2013
- Author(s)
  峯岸ゆり子、家島大輔、小林宏明、池在龍、川瀬和秀、山本哲也、関倫久、湯浅慎介、福田恵一、岩田岳
- Organizer
  第17回眼科分子生物学研究会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation]2013
- Author(s)
  Iwata T.
- Organizer
  National Eye Institute Audacious GoalMeeting
- Place of Presentation
  Potomac, Maryland, USA
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] Characterization of HtrA1 Promoter in Patients with Exudative Age-Related Macular Degeneration2013
- Author(s)
  Iejima D, Noda T, Mizota A, Iwata T.
- Organizer
  ARVO Annual Meeting 2013
- Place of Presentation
  Seattle, WA, USA
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] Animal models for glaucoma and age-related macular degeneration2013
- Author(s)
  Iwata T.
- Place of Presentation
  Gainesville, Florida, USA
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] Protemic analysis of ciliary body identifies abundant expression of RAB8/ERM,the secretory machinery for aqueous humor production.2013
- Author(s)
  Tanabe K, Kimura I, Okamoto H, Zai-Long Chi, Akahori M, Shimozawa N, Ebihara N, Murakami A, Iwata T
- Organizer
  World Glaucoma Congress
- Place of Presentation
  Vancouver Canada
- Data Source
  KAKENHI-PROJECT-24592663
[Presentation] 網膜疾患におけるExome解析2013
- Author(s)
  赤堀正和、岩田岳
- Organizer
  NGS現場の会(第三回)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] Molecular mechanism of POAG by optineurin E50K mutation2013
- Author(s)
  Iwata T.
- Organizer
  Asia ARVO 2013
- Place of Presentation
  New Delhi,India
- Data Source
  KAKENHI-PROJECT-25670742
[Presentation] 毛様体におけるRab8およびERM familyの発現変化の検討2012
- Author(s)
  田邊和彦，木村至，岡本はる，村上晶，岩田岳
- Organizer
  第23回日本緑内障学会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24592663
[Presentation] Inhibition of drusen formation by Compstatin in cynomolgus monkey with early-onset macular degeneration2011
- Author(s)
  Iwata, et al
- Organizer
  Aegean Conferences
- Place of Presentation
  Rhodes, Greece
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] Dominant mutations in RP1L1 are responsible for occult macular dystrophy (Miyake's Disease)2011
- Author(s)
  Iwata, et al
- Organizer
  ASHG
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] Analysis of colocalization of Rab8 and ERM family in the ocular ciliary body2010
- Author(s)
  Kimura I, Iwata T, et al
- Organizer
  ARVO 2010 Annual meeting
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-21592253
[Presentation] Analysis of Colocalization of Rab8 and ERM Family in the Ocular Ciliary Body2010
- Author(s)
  Kimura I, Okamoto H, Chil Z.-L, Akahori M, Suzuki MT, Iwata T
- Organizer
  Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale USA
- Data Source
  KAKENHI-PROJECT-21592253
[Presentation] Overexpression of mutant OPTN and WDR36 leads to a progressive retinal degeneration in mice2010
- Author(s)
  Chi ZL. Akahori M, Obazawa M, Minami M, Noda T, Nakaya N, Tomarev S, Kawase K, Yamamoto T, Noda S, Sasaoka M, Shimazaki A, Sergeev Y, Takada Y, Iwata T.
- Organizer
  50th American Society for Cell Biology
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] Analysis of Colocalization of Rab8 and ERM Family in the Ocular Body2010
- Author(s)
  I. Kimura, H. Okamoto, Z. L. Chi, M. Akahori, M. T. Suzuki, T. Iwata
- Organizer
  Association for Research in Vision and Ophthalmology
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] CHARACTERIZATION OF GLIA CELLS IN OPTN AND WDR36 TRANSGENIC MICE2010
- Author(s)
  T. Iwata. Z. L. Chi, M. Akahori, Y. Takada, N. Nakaya, S. Tomarev, Y. Sergeev
- Organizer
  19th International Congress for Eye Research
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] 加齢黄斑変性の発症機序とモデル動物を用いた予防・治療法の開発2009
- Author(s)
  岩田岳
- Organizer
  第63回国立病院総合医学会
- Place of Presentation
  仙台国際センター(仙台)
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] 遺伝情報を応用した病態解析とモデル作成2009
- Author(s)
  岩田岳, 他
- Organizer
  第113回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] 「失明に至る眼の疾患に挑む」加齢黄斑変性の霊長類モデル、遺伝子解析からの創薬ターゲット2009
- Author(s)
  岩田岳
- Organizer
  第34回ヒューマンサイエンス総合研究セミナー
- Place of Presentation
  砂防会館(東京)
- Year and Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] Susceptibility genes and animal models of glaucoma2009
- Author(s)
  Takeshi Iwata, et al.
- Organizer
  Asia Association for Research in Vision and Ophthalmology
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] 緑内障遺伝子WDR36トランスジェニックマウスの解析2009
- Author(s)
  池在龍、木村至、岩田岳
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2009-04-16
- Data Source
  KAKENHI-PROJECT-21592253
[Presentation] 毛様体におけるRab8 とERM family の局在についての検討2009
- Author(s)
  木村至、岩田岳
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2009-04-16
- Data Source
  KAKENHI-PROJECT-21592253
[Presentation] Suppression of drusen formation by Compstatin(POT-4), a peptide inhibitor of complement component C3 activation, on cynomolgus monkey with early-onset macular degeneration2009
- Author(s)
  岩田岳
- Organizer
  Aegean Conference
- Place of Presentation
  Crete, Greece
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] Overexpression of Mutated Optineurin and WDR36 Leads to Norm al Tension Glaucoma in Mice2009
- Author(s)
  岩田岳
- Organizer
  Association for Research in Vision and Ophthalmology
- Place of Presentation
  USA, Fort Lauderdale
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] Japanese contribution to the global eye research-past, present and future2009
- Author(s)
  岩田岳
- Organizer
  Asia Association for Research in Vision and Ophthalmology
- Place of Presentation
  Hyderabad, India
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] 緑内障遺伝子WDW36トランスジェニックマウスの解析2009
- Author(s)
  池在龍、安本史恵、皆見政好、尾羽澤実、赤堀正和、木村至、岩田岳
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2009-04-16
- Data Source
  KAKENHI-PROJECT-21592253
[Presentation] 遺伝情報を応用した病態解析とモデル作成2009
- Author(s)
  岩田岳
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム(東京)
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] Overexpression of Mutated Optineurin and WDR36 Leads to Normal Tension Glaucoma in Mice2009
- Author(s)
  Takeshi Iwata, et al.
- Organizer
  Association for Research in Vision and Ophthalmology
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] 毛様体におけるRab8とERM family の局在についての検討2009
- Author(s)
  木村至、岡本はる、池在龍、皆見政好、岩田岳
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2009-04-16
- Data Source
  KAKENHI-PROJECT-21592253
[Presentation] Proteomic analysis of low molecular weight plasma proteins from patients with ocular diseases2009
- Author(s)
  岩田岳
- Organizer
  Asia Association for Research in Vision and Ophthalmology
- Place of Presentation
  Hyderabad, India
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] Susceptibility genes and animal models of glaucoma. Asia Association for Research in Vision and Ophthalmology2009
- Author(s)
  岩田岳
- Organizer
  Asia Association for Research in Vision and Ophthalmology
- Place of Presentation
  Hyderabad, India
- Data Source
  KAKENHI-PROJECT-21390471
[Presentation] Interaction of secreted myocilin and the cell surface proteins on NIH3T3 cells.2007
- Author(s)
  皆見政好、岩田岳
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  アメリカ合衆国フロリダ州
- Year and Date
  2007-05-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591948
[Presentation] Interaction of secreted myocilin and the cell surface proteins on NIH3T3 cells.2007
- Author(s)
  Minami M, Iwata T.
- Organizer
  The Association for Research in Vision Ophthalmology
- Place of Presentation
  FL, USA
- Year and Date
  2007-05-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591948
[Presentation] Interaction of secreted myocilin and the cell surface proteins on N工H3T3 cells.2007
- Author(s)
  皆見政好、岩田岳
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  アメリカ合衆国フロリダ州
- Year and Date
  2007-05-05
- Data Source
  KAKENHI-PROJECT-18591948

1. MIZOTA Atsushi (10239262)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
2. SHIMOZAWA Nobuhiro (50300786)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
3. MINAMI Masayoshi (70392800)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. KIMURA Itaru (60296663)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. NISHIMURA Toshihide (40366092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Okamoto Akiko (70450400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 西村俊秀 (40663092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. UENO Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
9. HARADA takayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. SUGA Akiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
11. SAKURADA Yoichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 柏木賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. 寺崎浩子

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
14. 行方和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 林孝彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
16. 角田和繁

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
17. 吉村長久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 篠田啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
19. 稲谷大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 赤堀正和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 豊田太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 間渕文彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 米山征吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 伊藤逸毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
25. 中山真央

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 松本直通

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 近藤峰生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 亀谷修平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IWATA Takeshi 岩田 岳

岩田 岳 イワタ タケシ

Research Projects

Research Products

Co-Researchers

Construction of Cynomologus Monkey Model for Hereditary Retinal Diseases : Diseases Mechanisms and TherapeuticPrincipal Investigator

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Development of disease monkey model for hereditary retinal disease by gene editingPrincipal Investigator

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Induction of Muller glia-derived retinal regeneration by expressing regeneration promoting genes

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Primate model to study drusen formation and development of therapeuticsPrincipal Investigator

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Development of cynomolgus monkey with hereditary retinal diseasesPrincipal Investigator

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Development and pathological characterization of genetically modified macaque monkey with eye disease.Principal Investigator

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The elucidation of glaucoma pathophysiology by the investigation of Rab8 and ERM family interaction in the ocular ciliary body

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Characterization of mouse models for glaucomaPrincipal Investigator

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T hestudyofinteractionbetweenRab8andERMfamily i ntheocularciliarybody

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原発開放隅角緑内障の原因遺伝子(Myocilin)の機能解析

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Functional analysis of primary open-angle glaucoma associated WDR36 gene.

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Analysis of glaucoma-related protein interactionPrincipal Investigator

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[Book] Advances in Vision Research Volume II, Essentials in Ophthalmology2018

Author(s)

Total Pages

IWATA Takeshi 岩田岳

岩田岳イワタタケシ