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KANEHIRA Masahiko  兼平 雅彦

ORCIDConnect your ORCID iD *help
Researcher Number 90374941
Other IDs
Affiliation (Current) 2025: 山梨大学, 大学院総合研究部, 准教授
Affiliation (based on the past Project Information) *help 2019 – 2023: 山梨大学, 大学院総合研究部, 准教授
2013 – 2021: 東北大学, 大学病院, 助教
2017: 東北大学, 東北大学病院, 助教
2017: 東北大学, 大学病院, 講師
2016: 東北大学, 加齢医学研究所, 助教 … More
2014: 東北大学, 大学院医学研究科, 助教
2012: 東北大学, 医学(系)研究科(研究院), 助手
2012: 東北大学, 大学院・医学系研究科, 非常勤講 師
2011 – 2012: 東北大学, 医学(系)研究科(研究院), 非常勤講師
2010: Tohoku University, 大学院・医学系・研究科, 非常勤講師
2010: 東北大学, 大学院・医学系研究科, 非常勤講師
2009: Tohoku University, 加齢医学研究所, 技術補佐員
2008: 東北大学, 加齢医学研究所, 技術補佐
2006 – 2007: 東北大学, 加齢医学研究所, 教育研究支援者
2006 – 2007: TOHOKU UNIVERSITY, INSTITUTE OF DEVELOPMENT, AGING AND CANCER, RESEARCHER, 加齢医学研究所, 研究員
2005: 東北大学, 加齢医学研究所, 講師(研究機関研究員) Less
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine / Basic Section 55040:Respiratory surgery-related / Basic Section 53030:Respiratory medicine-related / Hematology
Except Principal Investigator
Respiratory organ internal medicine / Basic Section 55040:Respiratory surgery-related / Basic Section 53030:Respiratory medicine-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 58010:Medical management and medical sociology-related / Science education
Keywords
Principal Investigator
細胞老化 / 間葉系幹細胞 / リゾホスファチジン酸 / 肺幹細胞 / 骨髄由来間葉系幹細胞 / 免疫逃避 / 免疫チェックポイント / 肺移植 / 呼吸器疾患 / COPD … More / オルガノイド / 呼吸器 / 加齢 / 慢性閉塞性肺疾患 / オートタキシン / 骨髄腫細胞 / 多発性骨髄腫 / stemness / リゾリン脂質 / 発生・分化 / 癌 / 癌幹細胞 / 肺癌 / 再生医療 / マウス肺障害モデル / アデノウイルスベクター / ブレオマイシン / 肝細胞増殖因子(HGF) / 組織修復 / ファイバー改変アデノウイルス / プレオマイシン肺障害 / 肝細胞増殖因子 / 肺線維症 / 細胞治療 / 遺伝子治療 … More
Except Principal Investigator
間葉系幹細胞 / 肺移植 / STC1 / 間質性肺炎 / 肺線維症 / 代謝 / 翻訳後修飾 / メタボローム / エピゲノム / ミトコンドリア / マクロファージ / 医学教育 / 成長因子 / 治療 / 易炎症性 / STAT3 / 炎症 / 加齢肺 / マイクロアレイ / 慢性拒絶反応 / マウス / 高齢 / RNAシークエンス / 加齢 / 肺水腫 / RNAシーケンス / 高齢ドナー / 虚血・再灌流傷害 / 肺換気 / 組織代謝 / 持続換気保存 / 肺保存 / 臓器保存 / lung preservation / lung transplantation / シミュレータ / 獣医 / 医療技術 / ウエットラボ / トレーニング / 外科手術 / 医療技術トレーニング / EPAs / EPAs / アウトカム基盤型教育 / wet lab  トレーニング / ウエットラボトレーニング / 摘出臓器シミュレータ / サージカルトレーニング / wet lab トレーニング / 拒絶反応 / 免疫抑制療法 / Type 1 regulatory T細胞 / CLAD / Lymphoid neogenesis / CTLA4-Ig / Type 1 regulatory T 細胞 / 慢性移植肺機能不全 / 吸入療法 / 新型コロナウイルス感染症 / 肺障害 / 脱共役呼吸 / SMAD7 / SOCS1 / 抗炎症作用 / 抗線維化作用 / 抗酸化作用 / Stanniocalcin-1 / 前駆細胞 / SASP / 老化 / 障害ストレス応答 / ERストレス / 酸化ストレス / エピジェネティクス / 動物福祉 / 評価方法 / Visual Analog Scale / 倫理観 / 初期研修医 / 外科手技 / non-technical skills / Wet Lab / intracellular signaling / molecular targeting drugs / oncogene addiction / tumorigenesis / anti-apoptotic / bronchiolar epithelial cell / lung adenocarcinoma / EGF receptor / 細胞内シグナル伝達 / 分子標的薬 / がん遺伝子依存 / 発癌 / 不死化 / 細気管支上皮細胞 / 肺腺癌 / EGF受容体 / アメリカ合衆国 / ワルブルグ効果 / 国際情報交換 / TGF-BETA / 液性因子 / 骨髄間葉系幹細胞 / 過酸化ストレス / 小胞体ストレス / 特発性肺線維症 / II型肺胞上皮細胞 / STAM1遺伝子 / DNAメチル化 / 加齢変化 / CCSP / SP-C / GFPトランスジェニックマウス / トランスジェニックマウス / 肺幹細胞 Less
  • Research Projects

    (19 results)
  • Research Products

    (39 results)
  • Co-Researchers

    (38 People)
  •  免疫逃避機構を応用した新たな肺移植の戦略Principal Investigator

    • Principal Investigator
      兼平 雅彦
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      University of Yamanashi
  •  Development of pro-inflammatory treatment by cross-sectional control of aging lung metabolism and epigenetics

    • Principal Investigator
      大河内 眞也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Tohoku University
  •  The new method for long-term hypothermic lung preservation with continuous ventilation

    • Principal Investigator
      Matsuda Yasushi
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Fujita Health University
  •  Why is prognosis of lung transplant recipient from elderly donors poor? –Elucidation of mechanisms and establishment of therapeutic intervention strategy-

    • Principal Investigator
      Okada Yoshinori
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Tohoku University
  •  Elucidation of the pathophysiology of pulmonary fibrosis and development of new treatments by applying metabolome analysis

    • Principal Investigator
      Ohkouchi Shinya
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Tohoku University
  •  Analysis of a relationship between age-related respiratory diseases and lysophosphatidic acidsPrincipal Investigator

    • Principal Investigator
      Kanehira Masahiko
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      University of Yamanashi
      Tohoku University
  •  A novel immunosuppresive therapy by Type 1 regulatory T cells after lung transplantation

    • Principal Investigator
      Hisashi Oishi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Tohoku University
  •  Ex vivo wet lab training system by veterinarian and surgeon

    • Principal Investigator
      Masafumi Noda
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58010:Medical management and medical sociology-related
    • Research Institution
      Tohoku University
  •  A new therapeutic strategy for multiple myeloma by targeting senescence of bone marrow microenvironmentPrincipal Investigator

    • Principal Investigator
      Kanehira Masahiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tohoku University
  •  倫理観育成とノンテクニカルスキル教育に着目した外科実習プログラムの構築と評価

    • Principal Investigator
      壹岐 裕子
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Science education
    • Research Institution
      Tohoku University
  •  Differantial Mechanism of Lung Cells induced by Mesenchymal Stem Cells and the Treatment of Intractable Respiratory Diseases

    • Principal Investigator
      Ohkouchi Shinya
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Tohoku University
  •  Production of human induced bronchiolar progenitors

    • Principal Investigator
      KIKUCHI Toshiaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Niigata University
  •  New Therapy for Intractable Pulmonary Fibrosis using Humoral Factors released from Mesenchymal Stem Cells

    • Principal Investigator
      OHKOUCHI Shinya
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Tohoku University
  •  Clarification of physiological function of lysophosphatidic acid in maintenance of lung stem cells and application for respiratory diseases.Principal Investigator

    • Principal Investigator
      KANEHIRA Masahiko
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Tohoku University
  •  Establishment of new strategy for targeting lung cancer stem cells by using bone marrow-derived mesenchymal stem cellsPrincipal Investigator

    • Principal Investigator
      KANEHIRA Masahiko
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Tohoku University
  •  Decrease of type II pneumocyte function by aging in the process oflung fibrosis : multi-aspect evaluation of STAM1 gene

    • Principal Investigator
      NUKIWA Toshihiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Tohoku University
  •  肺幹細胞の効率的分離法の開発と肺幹細胞の解析

    • Principal Investigator
      西條 康夫
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Tohoku University
  •  HGF導入骨髄由来間葉系幹細胞を用いた肺組織障害に対する新規治療法の開発Principal Investigator

    • Principal Investigator
      兼平 雅彦
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Tohoku University
  •  Activation mutations in EGF receptor kinase have the advantages of cell physiology in the bronchiolar region : Implication of anti-apoptotic signals and lung tumorigenesis and metastasis.

    • Principal Investigator
      NUKIWA Toshihiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      TOHOKU UNIVERSITY

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 2007 2006 Other

All Journal Article Presentation Patent Other

  • [Journal Article] Effect of CTLA4-Ig on Obliterative Bronchiolitis in a Mouse Intrapulmonary Tracheal Transplantation Model2021

    • Author(s)
      Suzuki Yamato、Oishi Hisashi、Kanehira Masahiko、Matsuda Yasushi、Hirama Takashi、Noda Masafumi、Okada Yoshinori
    • Journal Title

      ATCS

      Volume: 27 Issue: 6 Pages: 355-365

    • DOI

      10.5761/atcs.oa.20-00398

    • NAID

      130008131277

    • ISSN
      1341-1098, 2186-1005
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08167, KAKENHI-PROJECT-19K09040, KAKENHI-PROJECT-21K16529
  • [Journal Article] Targeting stanniocalcin‐1‐expressing tumor cells elicits efficient antitumor effects in a mouse model of human lung cancer2021

    • Author(s)
      Abe Kotaro、Kanehira Masahiko、Ohkouchi Shinya、Kumata Sakiko、Suzuki Yamato、Oishi Hisashi、Noda Masafumi、Sakurada Akira、Miyauchi Eisaku、Fujiwara Tohru、Harigae Hideo、Okada Yoshinori
    • Journal Title

      Cancer Medicine

      Volume: 10 Issue: 9 Pages: 3085-3100

    • DOI

      10.1002/cam4.3852

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08167, KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-18K08136, KAKENHI-PROJECT-19K17624, KAKENHI-PROJECT-21K08385
  • [Journal Article] Effect of CTLA4-Ig on obliterative bronchiolitis in a mouse intrapulmonary tracheal transplantation model2021

    • Author(s)
      Yamato Suzuki, Hisashi Oishi, Masahiko Kanehira, Yasushi Matsuda, Takashi Hirama, Masafumi Noda, Yoshinori Okada.
    • Journal Title

      Annals of Thoracic and Cardiovascular Surgery

      Volume: In press

    • NAID

      130008131277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08777
  • [Journal Article] Bone marrow mesenchymal stromal cells protect allograft lung transplants from acute rejection via the PD-L1/IL-17A axis2018

    • Author(s)
      Ishibashi Naoya、Watanabe Tatsuaki、Kanehira Masahiko、Watanabe Yui、Hoshikawa Yasushi、Notsuda Hirotsugu、Noda Masafumi、Sakurada Akira、Ohkouchi Shinya、Kondo Takashi、Okada Yoshinori
    • Journal Title

      Surgical Today

      Volume: 48 Issue: 7 Pages: 726-734

    • DOI

      10.1007/s00595-018-1643-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09205, KAKENHI-PROJECT-18K08136, KAKENHI-PROJECT-18K08167
  • [Journal Article] Muse Cells and Ischemia-Reperfusion Lung Injury.2018

    • Author(s)
      Yabuki H, Watanabe T, Oishi H, Katahira M, Kanehira M, Okada Y.
    • Journal Title

      Adv Exp Med Biol.

      Volume: 1103 Pages: 293-303

    • DOI

      10.1007/978-4-431-56847-6_16

    • ISBN
      9784431568452, 9784431568476
    • Data Source
      KAKENHI-PROJECT-18K08167
  • [Journal Article] 研修医に対する動物を用いた外科手技トレーニングと動物倫理2017

    • Author(s)
      壹岐裕子、野田雅史、工藤克昌、末田輝子、兼平雅彦、伊藤拓哉、松田安史、岡田克典、海野倫明
    • Journal Title

      胸部外科

      Volume: 70 Pages: 329-333

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12367
  • [Journal Article] Animal ethics and welfare education in wet-lab training can foster residents’ ethical values toward life2017

    • Author(s)
      Iki Y, Ito T, Kudo K, Noda M, Kanehira M, Sueta T, Miyoshi I, Kagaya Y, Okada Y, Unno M
    • Journal Title

      Exp. Anim.

      Volume: 66 Issue: 4 Pages: 313-320

    • DOI

      10.1538/expanim.17-0026

    • NAID

      130006187189

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08855, KAKENHI-PROJECT-17K07129, KAKENHI-PROJECT-16K15635, KAKENHI-PROJECT-15K09465
  • [Journal Article] Animal Ethics and Welfare Education in Wet-Lab Training can Foster Residents' Ethical Values toward Life2017

    • Author(s)
      Yuko Iki, Takuya Ito, Katsuyoshi Kudo, Masafumi Noda, Masahiko Kanehira, Teruko Sueta, Ichiro Miyoshi, Yutaka Kagaya, Yoshinori Okada, Michiaki Unno
    • Journal Title

      Experimental Animals

      Volume: 66

    • NAID

      130006187189

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12367
  • [Journal Article] Mesenchymal stem cells attenuate ischemia-reperfusion injury after prolonged cold ischemia in a mouse model of lung transplantation: a preliminary study.2017

    • Author(s)
      Watanabe T, Hoshikawa Y, Ishibashi N, Suzuki H, Notsuda H, Watanabe Y, Noda M, Kanehira M, Ohkouchi S, Kondo T, Okada Y.
    • Journal Title

      Surg Today

      Volume: 47 Issue: 4 Pages: 425-425

    • DOI

      10.1007/s00595-016-1391-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09205, KAKENHI-PROJECT-15K09465
  • [Journal Article] An Lysophosphatidic Acid Receptors 1 and 3 Axis Governs Cellular Senescence of Mesenchymal Stromal Cells and Promotes Growth and Vascularization of Multiple Myeloma.2017

    • Author(s)
      Kanehira M, Fujiwara T, Nakajima S, Okitsu Y, Onishi Y, Fukuhara N, Ichinohasama R, Okada Y, Harigae H.
    • Journal Title

      Stem Cells.

      Volume: 35 Issue: 3 Pages: 739-753

    • DOI

      10.1002/stem.2499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08609, KAKENHI-PROJECT-15K09447, KAKENHI-PROJECT-15K09465, KAKENHI-PROJECT-16K09819
  • [Journal Article] Mesenchymal Stem Cells Correct Inappropriate Epithelial-mesenchyme Relation in Pulmonary Fibrosis Using Stanniocalcin-1.2015

    • Author(s)
      Ono M, Ohkouchi S, Kanehira M, Tode N, Kobayashi M, Ebina M, Nukiwa T, Irokawa T, Ogawa H, Akaike T, Okada Y, Kurosawa H, Kikuchi T, Ichinose M.
    • Journal Title

      Mol Ther

      Volume: 23 Issue: 3 Pages: 549-560

    • DOI

      10.1038/mt.2014.217

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22240066, KAKENHI-PROJECT-23390219, KAKENHI-PROJECT-24591149, KAKENHI-PROJECT-24659399, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26670207, KAKENHI-PROJECT-15K09205
  • [Journal Article] Human marrow stromal cells downsize the stem cell fraction of lung cancers by fibroblast growth factor 10.2014

    • Author(s)
      Kanehira M, Kikuchi T, Santoso A, Tode N, Hirano T, Ohkouchi S, Tamada T, Sugiura H, Harigae H, Ichinose M.
    • Journal Title

      Mol Cell Biol

      Volume: 34 Issue: 15 Pages: 2848-56

    • DOI

      10.1128/mcb.00871-13

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23390219, KAKENHI-PROJECT-24591149, KAKENHI-PROJECT-24591150, KAKENHI-PROJECT-24659399, KAKENHI-PROJECT-26293195
  • [Journal Article] Targeting lysophosphatidic acid signaling retards culture-associated senescence of human marrow stromal cells2012

    • Author(s)
      Kanehira M, Kikuchi T, Ohkouchi S, Shibahara T, Tode N, Santoso A, Daito H, Ohta H, Tamada T, Nukiwa T
    • Journal Title

      PLoS One

      Volume: 7 Issue: 2 Pages: e32185-e32185

    • DOI

      10.1371/journal.pone.0032185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249052, KAKENHI-PROJECT-21590980, KAKENHI-PROJECT-23390219, KAKENHI-PROJECT-23790895, KAKENHI-PROJECT-24659399
  • [Journal Article] Mesenchymal stromal cells protect cancer cells from ROS-induced apoptosis and enhance the Warburg effect by secreting STC12012

    • Author(s)
      Ohkouchi S, Block GJ, Katsha AM, Kanehira M, Ebina M, Kikuchi T, Saijo Y, Nukiwa T, Prockop DJ
    • Journal Title

      Mol Ther

      Volume: 20(2) Issue: 2 Pages: 417-23

    • DOI

      10.1038/mt.2011.259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590980, KAKENHI-PROJECT-23790895, KAKENHI-PROJECT-24659399
  • [Journal Article] Targeting lysophosphatidic acid signaling retards2012

    • Author(s)
      Kanehira M, Kikuchi T et al.
    • Journal Title

      PLoS ONE

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790895
  • [Journal Article] Mesenchymal Stromal Cells Promote Tumor Growth Through the Enhancement of Neovascularization2011

    • Author(s)
      Suzuki K, Saijo Y, at all
    • Journal Title

      Molecular Medicine

      Volume: Vul.17 Issue: 7-8 Pages: 579-587

    • DOI

      10.2119/molmed.2010.00157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659160, KAKENHI-PROJECT-23790895
  • [Journal Article] Serial OX40 engagement on CD4+ T cells and natural killer T cells causes allergic airway inflammation2010

    • Author(s)
      Damayanti T, Kikuchi T, Zaini J, Daito H, Kanehira M, Kohu K, Ishii N, Satake M, Sugamura K, Nukiwa T.
    • Journal Title

      Am J Respir Crit Care Med. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390223
  • [Journal Article] Suppression of surfactant protein A by an epidermal growth factor receptor tyrosine kinase inhibitor exacerbates lung inflammation2008

    • Author(s)
      Inoue A, Xin H, Suzuki T, Kanehira M, Kuroki Y, Fukuhara T, Kikuchi T, Maemondo M, Nukiwa T, Saijo Y.
    • Journal Title

      Cancer Sci. 99(8)

      Pages: 1679-1684

    • NAID

      10024010194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390223
  • [Journal Article] Targeted delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells2007

    • Author(s)
      Xin H, Kanehira M, Saijo Y, et. al.
    • Journal Title

      Stem Cells 25

      Pages: 1618-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659236
  • [Journal Article] Targeted delivery of NK4 to multiple lung tumors by bone marrow-derived mesenchymal stem cells2007

    • Author(s)
      Kanehira M, Xin H, Saijo Y, et. al.
    • Journal Title

      Cancer Gene Therapy 14

      Pages: 894-903

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659236
  • [Journal Article] Targeted-Delivery of CX3CL1 to Multiple Lung Tumors by Mesenchymal Stem Cells.2007

    • Author(s)
      Xin H, Kanehira M, Mizuguchi H, Hayakawa T, Kikuchi T, et al.
    • Journal Title

      Stem Cells (in press)

    • Data Source
      KAKENHI-PROJECT-17790520
  • [Journal Article] Novel mast cell lines with enhanced proliferative and degranulative abilities established from temperature-sensitive SV40 large T antigen transgenic mice.2006

    • Author(s)
      Kanehira M, Kaifu T, Maya K, Kaji M, Nakamura A, et al.
    • Journal Title

      J Biochem (Tokyo) 140

      Pages: 211-220

    • NAID

      10018842937

    • Data Source
      KAKENHI-PROJECT-17790520
  • [Journal Article] Dendritic cells modified to express fractalkine/CX3CL1 in the treatment of preexisting tumors.2006

    • Author(s)
      Nukiwa M, Andarini S, Zaini J, Xin H, Kanehira M, et al.
    • Journal Title

      Eur J Immunol. 36

      Pages: 1019-1027

    • Data Source
      KAKENHI-PROJECT-17790520
  • [Patent] リゾリン脂質シグナル制御による幹細胞の維持増殖培養法2012

    • Inventor(s)
      菊地利明、兼平雅彦 、貫和敏博
    • Industrial Property Rights Holder
      菊地利明、兼平雅彦 、貫和敏博
    • Filing Date
      2012-01-06
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23790895
  • [Patent] リゾリン脂質シグナル制御による幹細胞の維持増殖培養法2012

    • Inventor(s)
      菊地利明、兼平雅彦、貫和敏博
    • Industrial Property Rights Holder
      国立大学法人 東北大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-12-17
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23790895
  • [Patent] リゾリン脂質シグナル制御による幹細胞の維持増殖培養法2012

    • Inventor(s)
      菊地利明、兼平雅彦、貫和敏博
    • Industrial Property Rights Holder
      菊地利明、兼平雅彦、貫和敏博
    • Filing Date
      2012
    • Data Source
      KAKENHI-PROJECT-23790895
  • [Presentation] 肺移植後閉塞性細気管支モデルに対するCTLA4-Igの繊維性閉塞抑制効果の検討-マウス肺内気管移植モデルを用いて-2020

    • Author(s)
      鈴木大和, 大石久,兼平雅彦, 渡辺有為, 野津田泰嗣, 平間崇, 鈴木隆哉, 松田安史, 野田雅史, 舟橋淳一, 桜田晃, 岡田克典
    • Organizer
      第36回日本肺および心肺移植研究会
    • Data Source
      KAKENHI-PROJECT-18K08777
  • [Presentation] ミネラル調節ホルモンStanniocalcin-1を標的とした新たな肺がん治療法の可能性2020

    • Author(s)
      兼平 雅彦、阿部 晧太郎、大河内 眞也、岡田 克典
    • Organizer
      第163回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08167
  • [Presentation] 実験用マウスのDeep Learningを用いた陰部画像からの発情検知システムの開発2020

    • Author(s)
      標智仁、兼平雅彦、神沼修、長友啓明
    • Organizer
      第67回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-18K08167
  • [Presentation] CTLA4-Ig Therapy Attenuates Bronchiolitis Obliterans after Mouse Intrapulmonary Trachial Transplantation Model through Possibility of Effect of LAG3+Tregs2019

    • Author(s)
      Y. Suzuki, H. Oishi, M. Kanehira, Y. Matsuda, T. Sado, M. Noda, J. Funahashi, A. Sakurada, Y. Okada.
    • Organizer
      ISHLT 2019 Annual Meeting and Scientific Sessions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08777
  • [Presentation] CTLA4-Ig attenuates fibrous airway obliteration in a mouse intrapulmonary tracheal transplantation model2019

    • Author(s)
      Yamato Suzuki, Hisashi Oishi, Masahiko Kanehira, Yasushi Matsuda, Tetsu Sado, Masafumi Noda, Jun-ichi Funahashi, Akira Sakurada, Yoshinori Okada
    • Organizer
      The international society for heart and lung transplantation 39th annual meeting and scientific sessions
    • Data Source
      KAKENHI-PROJECT-18K08777
  • [Presentation] マウス肺内気管移植モデルにおけるCTLA4-Igによる気管の線維性閉塞抑制効果の検討2019

    • Author(s)
      2.鈴木大和, 大石 久, 兼平雅彦, 松田安史, 佐渡 哲, 野田雅史, 桜田 晃, 岡田克典
    • Organizer
      第 35回日本肺および心肺移植研究会
    • Data Source
      KAKENHI-PROJECT-18K08777
  • [Presentation] 加齢に伴う呼吸器疾患におけるリゾホスファチジン酸シグナルの関与2019

    • Author(s)
      兼平雅彦、野田雅史、岡田克典
    • Organizer
      第162回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08167
  • [Presentation] マウス肺内気管移植モデルにおけるCTLA4-Igによる気管の線維性閉塞抑制効果の検討2019

    • Author(s)
      鈴木大和、大石 久、兼平雅彦、松田安史、佐渡 哲、野田雅史、舟橋淳一、桜田 晃、岡田克典
    • Organizer
      第35回日本肺および心肺移植研究会
    • Data Source
      KAKENHI-PROJECT-18K08777
  • [Presentation] 骨髄間葉系幹細胞による移植肺拒絶反応抑制効果の検討2018

    • Author(s)
      兼平雅彦,石橋直也,渡邉龍秋, 野田雅史,岡田克典
    • Organizer
      第65回 日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-18K08167
  • [Presentation] 医学教育におけるVisual Analog Scaleの新しい利用方法の提案2016

    • Author(s)
      壹岐裕子、野田雅史、工藤克昌、伊藤拓哉、兼平雅彦、海野倫明
    • Organizer
      日本シミュレーション医療教育学会
    • Place of Presentation
      浜松医科大学
    • Data Source
      KAKENHI-PROJECT-15K12367
  • [Presentation] The Enhancement Of Stanniocalcin-1 (STC1) Secretion Increases The Ability Of Mesenchymal Stem Cells (MSCs) Reducing Bleomycin-Induced Lung Fibrosis In Mice Model Through Inhibition Of ROS/Endoplasmic Reticulum Stress (ER-Stress)/TGFβ1 Pathway2014

    • Author(s)
      M. Ono, graduate student, S. Ohkouchi, M.D. PhD., M. Kanehira, PhD, N. Tode, MD, T. Kikuchi, MD, PhD, M. Ichinose, Prof
    • Organizer
      ATS 2014 San Diego
    • Place of Presentation
      San Diego USA
    • Data Source
      KAKENHI-PROJECT-24591149
  • [Presentation] The enhancement of Stannniocalcin-1 (STC1) secretion of Multipotent-Stromal-Cells (MSCs) increases the ability to reduce bleomycin-induced lung injuries.2013

    • Author(s)
      Manabu Ono*, Shinya Ohkouchi, Masahiko Kanehira, Naoki Tode, Makoto Kobayashi, Tadahisa Numakura, Toshiaki Kikuchi and Masakazu Ichinose.
    • Organizer
      APSR (Asian Pacific Society of Respirology) Annual Meeting 2013
    • Place of Presentation
      yokohama
    • Data Source
      KAKENHI-PROJECT-24591149
  • []

  • 1.  OHKOUCHI Shinya (40375035)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 8 results
  • 2.  Okada Yoshinori (90323104)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 6 results
  • 3.  Masafumi Noda (70400356)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 9 results
  • 4.  Hisashi Oishi (60451580)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 6 results
  • 5.  Matsuda Yasushi (00455833)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 6.  Kurosawa Hajime (60333788)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 7.  NUKIWA Toshihiro (40129036)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 8.  EBINA Masahito (10280885)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  TAZAWA Ryushi (70301041)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  TANAKA Nobuyuki (60280872)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  SUZUKI Takuji (80344670)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  INOUE Akira (70361087)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  Kikuchi Toshiaki (10280926)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 14.  Irokawa Toshiya (70375179)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 15.  HISATA Shu (60466571)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  FUKUHARA Tatsuro (80400365)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  NISHIO Kazuto (10208134)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  Ogawa Hiromasa (90361162)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  Yamada Mitsuhiro (00396483)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  GOMI Kazunori (20400335)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  西條 康夫 (10270828)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 22.  前門戸 任 (40344676)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  壹岐 裕子 (40747614)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 24.  末田 輝子 (20748446)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 25.  工藤 克昌 (30607768)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 26.  福地 純一郎 (00274043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  近藤 丘 (10195901)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  荒田 悠太郎 (20755011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  加賀谷 豊 (90250779)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  伊藤 拓哉 (70396539)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  佐渡 哲 (20396485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  平間 崇 (80510338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  星川 康 (90333814)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  藤野 直也 (10633670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  早坂 一希 (40964739)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  渡邉 龍秋 (70636034)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  ICHINOHASAMA Ryo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  福原 規子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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