AKAHANE Koshi 赤羽弘資

… Alternative Names

AKAHANE KOSHI 赤羽弘資

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Researcher Number	90377531
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 山梨大学, 大学院総合研究部, 講師 2017 – 2021: 山梨大学, 大学院総合研究部, 助教 2016: 山梨大学, 総合研究部, 助教 2010 – 2012: University of Yamanashi, 医学部附属病院, 助教 2011: 山梨大学, 医学部・附属病院, 助教 … More 2010: 山梨大学, 医学部附属病院, 診療助教 2009: University of Yamanashi, 医学部附属病院, 医員 2007: 山梨大学, 大学院・医学工学総合研究部, 医学研究員 2006: University of Yamanashi, Department of Research Interdisciplinary Graduate School of Medicine and Engineering, Research Fellow, 大学院医学工学総合研究部, 医学研究員 2004 – 2005: 山梨大学, 医学部附属病院, 医員 Less
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related / Biological Sciences
Keywords	Principal Investigator 急性リンパ性白血病 / 抗がん剤耐性 / CD33 / 骨髄球系抗原 / T細胞型急性リンパ性白血病 / 薬剤耐性 / TCF3::HLF / ＴＰ53変異 / TP53変異 / 癌 … More / T-ALL / p38 MAPK / TYK2 / T細胞性急性リンパ性白血病 / E2A-HLF / CD13 / B前駆細胞型急性リンパ性白血病 / FasL / 細胞障害因子 / TRAIL / 細胞傷害因子 / アポトーシス / 白血病 … More Except Principal Investigator 白血病 / 細胞傷害因子 / TRAIL / アポトーシス / 移植片対白血病効果 / 個別化治療 / ゲノム編集 / 薬剤感受性 / 難治性 / 急性リンパ性白血病 / apoptosis / 11q23転座型白血病 / CD33 / BCR-ABL / 小胞体ストレス / E2A-HLF / 17;19転座 / ゲノム編集技術 / ゲノム解析 / ゲノム情報 / がんゲノム / Ph1-positive leukemia / T-cell leukemia / 11q23 rearranged leukemia / GVL effect / endoplasmic reticulum-stress / cytotoxic ligands / leukemia / Fas / 同種造血幹細胞移植 / Ph1陽性白血病 / T細胞型急性リンパ性白血病 / LMO2 / t(17;19) / cytotoxic ligand / 11q23 translocation / childhood leukemia / FLT-3遺伝子 / PKC412 / Imatinib / Philadelphia染色体陽性白血病 / 難治性小児白血病 / 分子標的療法 / 細胞周期 / LMO2遺伝子 / 難治性白血病 / LM02 / 11q23転座 / 小児白血病 / 造血幹細胞移植 / 細胞障害因子 / DR5受容体 / DR4 Less

予後不良なTCF3::HLF陽性急性リンパ性白血病の抗がん剤耐性を克服する治療の開発Principal Investigator
- Principal Investigator
  
  赤羽弘資
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  University of Yamanashi
難治性急性リンパ性白血病に対するプレシジョン・メディシンを目指した多分野融合研究
- Principal Investigator
  
  犬飼岳史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  University of Yamanashi
Involvement of TP53 mutations in chemoresistance of B-precursor acute lymphoblastic leukemiaPrincipal Investigator
- Principal Investigator
  
  Akahane Koshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  University of Yamanashi
Integrated study aiming at development of precision medicine for poor prognostic acute lymphoblastic leukemia
- Principal Investigator
  
  Inukai Takeshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  University of Yamanashi
Development of novel therapeutic strategy targeting TYK2 for T-cell acute lymphoblastic leukemiaPrincipal Investigator
- Principal Investigator
  
  AKAHANE KOSHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
The analysis of CD33 antigens expressed in acute lymphoblastic leukemiaPrincipal Investigator
- Principal Investigator
  
  AKAHANE Koshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Clinical significance of cytotoxic factor-mediated graft-versus-leukemia effect against high-risk childhood leukemia
- Principal Investigator
  
  INUKAI Takeshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
The analysis of myeloid antigens expressed in acute lymphoblastic leukemiaPrincipal Investigator
- Principal Investigator
  
  AKAHANE Koshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
細胞傷害因子の移植片対白血病効果における意義と臨床応用に向けた研究
- Principal Investigator
  
  INUKAI Takeshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Yamanashi
小児急性リンパ性白血病における感染を契機にした自然退縮の機序の解明Principal Investigator
- Principal Investigator
  
  赤羽弘資
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Establishment of new-therapy and analysis of mechanisms for resistance to apoptosis in poor-prognostic childhood leukemia
- Principal Investigator
  
  NAKAZAWA Shinpei
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Anti-leukemic activity of cytotoxic ligands against poor-prognostic childhood leukemia
- Principal Investigator
  
  INUKAI Takeshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi

[Journal Article] Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia2024
- Author(s)
  Aoki Kazunari、Hyuga Mizuki、Tarumoto Yusuke、Nishibuchi Gohei、Ueda Atsushi、Ochi Yotaro、Sugino Seiichi、Mikami Takashi、Kobushi Hirokazu、Kato Itaru、Akahane Koshi、Inukai Takeshi、Takaori-Kondo Akifumi、Takita Junko、Ogawa Seishi、Yusa Kosuke
- Journal Title
  
  Blood
  
  Volume: 143 Issue: 7 Pages: 604-618
- DOI
  10.1182/blood.2023020857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18264, KAKENHI-PROJECT-21K08393, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-21H04959, KAKENHI-PROJECT-23K24298
[Journal Article] Application of prime editing system to introduce P53 R248Q hotspot mutation in acute lymphoblastic leukemia cell line2024
- Author(s)
  Nguyen Thao、Aida Tomomi、Iijima‐Yamashita Yuka、Tamai Minori、Nagamachi Akiko、Kagami Keiko、Komatsu Chiaki、Kasai Shin、Akahane Koshi、Goi Kumiko、Inaba Toshiya、Sanada Masashi、Inukai Takeshi
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 6 Pages: 0-0
- DOI
  10.1111/cas.16162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08395, KAKENHI-PROJECT-23K24298
[Journal Article] Utility of ASNS gene methylation evaluated with the HPLC method as a pharmacogenomic biomarker to predict asparaginase sensitivity in BCP-ALL2023
- Author(s)
  Watanabe Atsushi、Miyake Kunio、Yamada Yuriko、Sunamura Ei-Ichiro、Yotani Takuya、Kagami Keiko、Kasai Shin、Tamai Minori、Harama Daisuke、Akahane Koshi、Goi Kumiko、Sakaguchi Kimiyoshi、Goto Hiroaki、Kitahara Shinichiro、Inukai Takeshi
- Journal Title
  
  Epigenetics
  
  Volume: 18 Issue: 1 Pages: 2268814-2268814
- DOI
  10.1080/15592294.2023.2268814
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] Targeting Poly(ADP)ribose polymerase in BCR/ABL1-positive cells2023
- Author(s)
  Hiroki Haruka、Ishii Yuko、Piao Jinhua、Namikawa Yui、Masutani Mitsuko、Honda Hiroaki、Akahane Koshi、Inukai Takeshi、Morio Tomohiro、Takagi Masatoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 7588-7588
- DOI
  10.1038/s41598-023-33852-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24298, KAKENHI-PROJECT-23K27442
[Journal Article] Generation of Philadelphia chromosome in human leukemia by DNA breaks on the BCR and ABL1 genes using CRISPR/Cas9 system.2023
- Author(s)
  Tamai M, Fujisawa S, Nguyen Thao TT, Komatsu C, Kagami K, Kamimoto K, Omachi K, Kasai S, Harama D, Watanabe A, Akahane K, Goi K, Naka K, Kaname T, Teshima T, and Inukai T
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: 30 Issue: 1 Pages: 38-50
- DOI
  10.1038/s41417-022-00522-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19353, KAKENHI-PROJECT-21K15528, KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-23K24298
[Journal Article] CRISPR/Cas9-Mediated Induction of Relapse-Specific NT5C2 and PRPS1 Mutations Confers Thiopurine Resistance as a Relapsed Lymphoid Leukemia Model2023
- Author(s)
  Nguyen Thao Thu Thi、Tanaka Yoichi、Sanada Masashi、Hosaka Masumi、Tamai Minori、Kagami Keiko、Komatsu Chiaki、Somazu Shinpei、Harama Daisuke、Kasai Shin、Watanabe Atsushi、Akahane Koushi、Goi Kumiko、Inukai Takeshi
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 103 Issue: 4 Pages: 199-210
- DOI
  10.1124/molpharm.122.000546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] BCL6 inhibition ameliorates resistance to ruxolitinib in <i>CRLF2</i>-rearranged acute lymphoblastic leukemia2022
- Author(s)
  Tsuzuki Shinobu、Yasuda Takahiko、Goto Hiroaki、Maeda Naoko、Akahane Koshi、Inukai Takeshi、Yamamoto Hideyuki、Karnan Sivasundaram、Ota Akinobu、Hyodo Toshinori、Konishi Hiroyuki、Hosokawa Yoshitaka、Kiyoi Hitoshi、Hayakawa Fumihiko
- Journal Title
  
  Haematologica
  
  Volume: 108 Issue: 2 Pages: 394-408
- DOI
  10.3324/haematol.2022.280879
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08426, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-19K09292, KAKENHI-PROJECT-23K24118, KAKENHI-PROJECT-23K24298, KAKENHI-PROJECT-23K24362
[Journal Article] Successful treatment of intractable gastrointestinal tract graft-vs-host disease with oral beclomethasone dipropionate in pediatric and young adult patients2022
- Author(s)
  Akahane Koshi、Watanabe Atsushi、Somazu Shinpei、Harama Daisuke、Shinohara Tamao、Kasai Shin、Oshiro Hiroko、Goi Kumiko、Hasuda Norio、Ozawa Chihiro、Sugita Kanji、Inukai Takeshi
- Journal Title
  
  Medicine
  
  Volume: 101 Issue: 11
- DOI
  10.1097/md.0000000000029054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] Association of allele-specific methylation of the <i>ASNS</i> gene with asparaginase sensitivity and prognosis in T-ALL2022
- Author(s)
  Akahane Koshi、Kimura Shunsuke、Miyake Kunio、Watanabe Atsushi、Kagami Keiko、Yoshimura Kentaro、Shinohara Tamao、Harama Daisuke、Kasai Shin、Goi Kumiko、Kawai Tomoko、Hata Kenichiro、Kiyokawa Nobutaka、Koh Katsuyoshi、他7名
- Journal Title
  
  Blood Advances
  
  Volume: 6 Issue: 1 Pages: 212-224
- DOI
  10.1182/bloodadvances.2021004271
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07728, KAKENHI-PROJECT-20K21707, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20H03928, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-21K19405
[Journal Article] CN470 is a BET/CBP/p300 multi-bromodomain inhibitor and has an anti-tumor activity against MLL-rearranged acute lymphoblastic leukemia2022
- Author(s)
  Imayoshi Natsuki、Yoshioka Makoto、Tanaka Kuniaki、Yang Shyh-Ming、Akahane Koshi、Toda Yuki、Hosogi Shigekuni、Inukai Takeshi、Okada Seiji、Maloney David J.、Nakahata Tatsutoshi、Takita Junko、Kato Itaru、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 590 Pages: 49-54
- DOI
  10.1016/j.bbrc.2021.12.078
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20J22374, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-20K17388, KAKENHI-PROJECT-23K24298
[Journal Article] Genome-wide CRISPR-Cas9 screen identifies rationally designed combination therapies for CRLF2-rearranged Ph-like ALL2022
- Author(s)
  Sasaki Kensuke、Yamauchi Takuji、Semba Yuichiro、Nogami Jumpei、Imanaga Hiroshi、Terasaki Tatsuya、Nakao Fumihiko、Akahane Koshi、Inukai Takeshi、Verhoeyen Els、Akashi Koichi、Maeda Takahiro
- Journal Title
  
  Blood
  
  Volume: 139 Issue: 5 Pages: 748-760
- DOI
  10.1182/blood.2021012976
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-21H04827
[Journal Article] Prominence of NUDT15 genetic variation associated with 6‐mercaptopurine tolerance in a genome‐wide association study of Japanese children with acute lymphoblastic leukaemia2022
- Author(s)
  Tanaka Yoichi、Urayama Kevin Y.、Mori Makiko、Arakawa Yuki、Hasegawa Daisuke、Noguchi Yasushi、Yanagimachi Masakatsu、Keino Dai、Ota Setsuo、Akahane Koshi、Inukai Takeshi、Hangai Mayumi、Kawaguchi Takahisa、Takagi Masatoshi、Koh Katsuyoshi、Matsuda Fumihiko、Manabe Atsushi
- Journal Title
  
  British Journal of Haematology
  
  Volume: 199 Issue: 2 Pages: 260-269
- DOI
  10.1111/bjh.18405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] Introduction of the T315I gatekeeper mutation of BCR/ABL1 into a Philadelphia chromosome-positive lymphoid leukemia cell line using the CRISPR/Cas9 system2022
- Author(s)
  Nguyen Thao T. T.、Tamai Minori、Harama Daisuke、Kagami Keiko、Kasai Shin、Watanabe Atsushi、Akahane Koshi、Goi Kumiko、Inukai Takeshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 116 Issue: 4 Pages: 534-543
- DOI
  10.1007/s12185-022-03369-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] Synergistic effect of combined PI3 kinase inhibitor and PARP inhibitor treatment on BCR/ABL1-positive acute lymphoblastic leukemia cells2022
- Author(s)
  Hiroki Haruka、Akahane Koshi、Inukai Takeshi、Morio Tomohiro、Takagi Masatoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 117 Issue: 5 Pages: 748-758
- DOI
  10.1007/s12185-022-03520-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24298
[Journal Article] Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia2022
- Author(s)
  Tamai Minori、Kasai Shin、Akahane Koshi、Thu Thao Nguyen、Kagami Keiko、Komatsu Chiaki、Abe Masako、Watanabe Atsushi、Goi Kumiko、Miyake Kunio、Inaba Toshiya、Takita Junko、Goto Hiroaki、Minegishi Masayoshi、Iwamoto Shotaro、Sugita Kanji、Inukai Takeshi
- Journal Title
  
  The Journal of Steroid Biochemistry and Molecular Biology
  
  Volume: 218 Pages: 106068-106068
- DOI
  10.1016/j.jsbmb.2022.106068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-20H03928, KAKENHI-PROJECT-21H02948, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-23K24298
[Journal Article] Epigenetic Modification of Death Receptor Genes for TRAIL and TRAIL Resistance in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia2021
- Author(s)
  Watanabe Atsushi、Miyake Kunio、Akahane Koshi、Goi Kumiko、Kagami Keiko、Yagita Hideo、Inukai Takeshi
- Journal Title
  
  Genes
  
  Volume: 12 Issue: 6 Pages: 864-864
- DOI
  10.3390/genes12060864
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21707, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20H03928
[Journal Article] IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform2021
- Author(s)
  Harama Daisuke、Yahata Takashi、Kagami Keiko、Abe Masako、Ando Norie、Kasai Shin、Tamai Minori、Akahane Koshi、Inukai Takeshi、Kiyokawa Nobutaka、Ibrahim Abd Aziz、Ando Kiyoshi、Sugita Kanji
- Journal Title
  
  Cell Death Discovery
  
  Volume: 7 Issue: 1 Pages: 1-14
- DOI
  10.1038/s41420-021-00523-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-18K14702, KAKENHI-PROJECT-23K21386
[Journal Article] KIR3DL1 Allotype-Dependent Modulation of NK Cell Immunity against Chronic Myeloid Leukemia2021
- Author(s)
  Izumi Kiyotaka、Shindo Takero、Ngo Huong Thi、Nakayama-Hosoya Kaori、Akahane Koshi、Tamai Minori、Nguyen Thao T. T.、Kawana-Tachikawa Ai、Inukai Takeshi、Takaori-Kondo Akifumi
- Journal Title
  
  ImmunoHorizons
  
  Volume: 5 Issue: 8 Pages: 687-702
- DOI
  10.4049/immunohorizons.2100054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08812, KAKENHI-PROJECT-19H03615
[Journal Article] Combination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells2021
- Author(s)
  Malyukova Alena、Ujvari Dorina、Yektaei-Karin Elham、Zovko Ana、Madapura Harsha S.、Keszei Marton、Nagy Noemi、Lotfi Kourosh、Bj?rn Niclas、Wallvik Jonas、Tamai Minori、Nguyen Thao T. T.、Akahane Koshi、Inukai Takeshi、Stenke Leif、Salamon Daniel
- Journal Title
  
  Cell Death & Disease
  
  Volume: 12 Issue: 10
- DOI
  10.1038/s41419-021-04154-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells2021
- Author(s)
  Somazu S, Tanaka Y, Tamai M, Watanabe A, Kagami K, Abe M, Harama D, Shinohara T, Akahane K, Goi K, Sugita K, Moriyama T, Yang J, Goto H, Minegishi M, Iwamoto S,?Takita J, Inukai T
- Journal Title
  
  J Cell Mol Med
  
  Volume: 25 Issue: 22 Pages: 10521-10533
- DOI
  10.1111/jcmm.16981
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-21K19405
[Journal Article] High prevalence of MEF2D fusion in human B-cell precursor acute lymphoblastic leukemia cell lines.2020
- Author(s)
  Akahane K, Yasuda T, Tsuzuki S, Hayakawa F, Kiyokawa N, Somazu S, Watanabe A, Kagami K, Abe M, Harama D, Goi K, Kawazu M, Kojima S, Imamura T, Goto H, Iwamoto S, Minegishi M, Abe M, Hojo H, Inaba T, Mano H, Sugita K, Inukai T.
- Journal Title
  
  Hematol Oncol.
  
  Volume: 38 Issue: 4 Pages: 614-617
- DOI
  10.1002/hon.2762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19H03615
[Journal Article] Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia.2020
- Author(s)
  Kumar R, Pereira RS, Zanetti C, Minciacchi VR, Merten M, Meister M, Niemann J, Dietz MS, Russel N, Schnutgen F, Tamai M, Akahane K, Inukai T, Oellerich T, Kvasnicka HM, Pfeifer H, Nicolini FE, Heilemann M, Van Etten RA, Krause DS.
- Journal Title
  
  Leukemia
  
  Volume: 34 Issue: 8 Pages: 2087-2101
- DOI
  10.1038/s41375-020-0866-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL2020
- Author(s)
  Atsushi Watanabe, Kunio Miyake, Jessica Nordlund, Ann-Christine Syvanen, Louise van der Weyden, Hiroaki Honda, Norimasa Yamasaki, Akiko Nagamachi, Toshiya Inaba, Tomokatsu Ikawa, Kevin Y Urayama, Nobutaka Kiyokawa, Akira Ohara, Shunsuke Kimura, Yasuo Kubota, Junko Takita, Hiroaki Goto, Kimiyoshi Sakaguchi, et al.
- Journal Title
  
  Blood
  
  Volume: 136 Issue: 20 Pages: 2319-2333
- DOI
  10.1182/blood.2019004090
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08318, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-20K21707, KAKENHI-PROJECT-19KK0222, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-20H03928, KAKENHI-PROJECT-18K08357, KAKENHI-PROJECT-20H00528
[Journal Article] Association of relapse-linked ARID5B single nucleotide polymorphisms with drug resistance in B-cell precursor acute lymphoblastic leukemia cell lines.2020
- Author(s)
  Tamai M, Huang M, Kagami K, Abe M, Somazu S, Shinohara T, Harama D, Watanabe A, Akahane K, Goi K, Sugita K, Goto H, Minegishi M, Iwamoto S, Inukai T.
- Journal Title
  
  Cancer Cell Int
  
  Volume: 20 Issue: 1 Pages: 434-434
- DOI
  10.1186/s12935-020-01524-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] Inherited genetic variants associated with glucocorticoid sensitivity in leukaemia cells.2020
- Author(s)
  Shinohara T, Urayama KY, Watanabe A, Akahane K, Goi K, Huang M, Kagami K, Abe M, Sugita K, Okada Y, Goto H, Minegishi M, Iwamoto S, Inukai T.
- Journal Title
  
  J Cell Mol Med
  
  Volume: 24 Issue: 22 Pages: 12920-12932
- DOI
  10.1111/jcmm.15882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] Successful hematopoietic stem cell transplantation from an HLA-mismatched parent for engraftment failure after unrelated cord blood transplantation in patients with juvenile myelomonocytic leukemia: Report of two cases.2019
- Author(s)
  Akahane K, Watanabe A, Furuichi Y, Somazu S, Oshiro H, Goi K, Sakashita K, Muramatsu H, Hama A, Takahashi Y, Koike K, Kojima S, Sugita K, Inukai T.
- Journal Title
  
  Pediatr Transplant.
  
  Volume: 3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03615
[Journal Article] High ENT1 and DCK gene expression levels are a potential biomarker to predict favorable response to nelarabine therapy in T-cell acute lymphoblastic leukemia.2019
- Author(s)
  Akahane K, Murakami Y, Kagami K, Abe M, Harama D, Shinohara T, Watanabe A, Goi K, Nishi R, Yamauchi T, Kimura S, Takita J, Look AT, Minegishi M, Sugita K, Inukai T.
- Journal Title
  
  Hematol Oncol.
  
  Volume: 37 Issue: 4 Pages: 516-519
- DOI
  10.1002/hon.2654
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07294, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-18K19467
[Journal Article] Resistance of t(17;19)-acute lymphoblastic leukemia cell lines to multiagents in induction therapy.2019
- Author(s)
  Watanabe A, Inukai T, Kagami K, Abe M, Takagi M, Fukushima T, Fukushima H, Nanmoku T, Terui K, Ito T, Toki T, Ito E, Fujimura J, Goto H, Endo M, Look T, Kamps M, Minegishi M, Takita J, Inaba T, Takahashi H, Ohara A, Harama D, Shinohara T, Somazu S, Oshiro H, Akahane K, Goi K, Sugita K.
- Journal Title
  
  Cancer Med.
  
  Volume: 7 Issue: 11 Pages: 5274-5288
- DOI
  10.1002/cam4.2356
- NAID
  120007159553
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-18K19467
[Journal Article] Anti-leukemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukemia2017
- Author(s)
  Akahane K, Li Z, Etchin J, Berezovskaya A, Gjini E, Masse CE, Miao W, Rocnik J, Kapeller R, Greenwood JR, Tiv H, Sanda T, Weinstock DM and Look AT
- Journal Title
  
  Br J Haematol
  
  Volume: 177 Issue: 2 Pages: 271-282
- DOI
  10.1111/bjh.14563
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10019
[Journal Article] Endoplasmic reticulum stress inducers, but not imatinib, sensitize Philadelphia chromosome-positive leukemia cells to TRAIL-mediated apoptosis2011
- Author(s)
  Zhang X, Inukai T, Akahane K, Hirose K, Kuroda I, et al
- Journal Title
  
  Leuk Res
  
  Volume: 35 Pages: 940-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] Resistance of T-cell acute lymphoblastic leukemia totumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis2010
- Author(s)
  Akahane K, Inukai T, Hirose K, Kuroda I, et al
- Journal Title
  
  Exp Hematol
  
  Volume: 38 Pages: 885-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] Specific induction of CD33 expression by E2A-HLF : the first evidence for aberrant myeloid antigen expression in ALL by a fusion transcription factor.2010
- Author(s)
  Akahane K, Inukai T, Inaba T, et al
- Journal Title
  
  Leukemia 24
  
  Pages: 865-869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790976
[Journal Article] Specific induction of CD33 expression by E2A-HLF : the first evidence for aberrant myeloid antigen expression in ALL by a fusion transcription factor.2010
- Author(s)
  Akahane K
- Journal Title
  
  Leukemia 24(4)
  
  Pages: 865-869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790976
[Journal Article] Resistance of T-cell acute lymphoblastic leukemia to tumor necrosis fact or-related apoptosis-inducing ligand-mediated apoptosis.2010
- Author(s)
  Akahane K
- Journal Title
  
  Exp Hematol.
  
  Volume: 38 Pages: 885-895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] Revision of the cytological diagnosis of CNS relapse into aseptic meningitis in a patient with TEL-AMLI-positive acute lymphoblastic leukaemia by FISH analysis of mononuclear cells in cerebrospinal fluid2007
- Author(s)
  Inukai T, Akahane K, Kuroda I, Honna H, Sugita K, ら
- Journal Title
  
  Histopathology 50
  
  Pages: 947-949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015020
[Journal Article] Monitoring neutrophil engraftment in allogeneic stem cell transplantation by flow cytometric analysis of neutrophil-specific antigens NA1 and NA22007
- Author(s)
  Inukai T, Akahane K, Honna H, Sugita K, ら
- Journal Title
  
  Br J Haematol 139
  
  Pages: 280-283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015020
[Journal Article] Fms-like Tyrosine Kinase 3 Ligand Stimulation Induces MLL-Rearranged Leukemia Cells into Quiescence Resistant to Antileukemic Agents2007
- Author(s)
  Furuichi Y, Inukai T, Akahane K, Honna H, Kuroda I, Sugita K, ら
- Journal Title
  
  Cancer Res. 67
  
  Pages: 9852-9861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015020
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Okamoto T, Nemoto A, Akahane K, Takahashi K, Sato H, Goi K, Nakazawa S, Sugita K.
- Journal Title
  
  Leukemia 20・2
  
  Pages: 363-365
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Okamoto T, Nemoto A, Akahane K, Takahashi K, Sato H, Goi K, Nakazawa S, Sugita K.
- Journal Title
  
  Leukemia 20・2
  
  Pages: 363-365
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Okamoto T, Nemoto A, Akahane K, Takahashi K, Sato H, Goi K, Nakazawa S, Sugita K.
- Journal Title
  
  Leukemia 20(2)
  
  Pages: 363-365
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Yokota S, Akahane K, Goi K, Nakazawa S, Sugita K. et al.
- Journal Title
  
  Leukemia 20・2
  
  Pages: 363-5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse.2006
- Author(s)
  Inukai T, Akahane K
- Journal Title
  
  Leukemia 20(2)
  
  Pages: 363-365
- Data Source
  KAKENHI-PROJECT-17790694
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocyte after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Hirose K, Akahane K.Nemoto A, Takahashi K, Sato H, Kagami K, Goi K, Sugita K, Nakazawa S.
- Journal Title
  
  International Journal of Hematology 82・2
  
  Pages: 132-136
- Data Source
  KAKENHI-PROJECT-16390297
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Hirose K, Akahane K, Nemoto A, Takahashi K, Sato H, Kagami K, Goi K, Sugita K, Nakazawa S.
- Journal Title
  
  International Journal of Hematol. 82(2)
  
  Pages: 132-136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Induction of impaired membrane phospholipids asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Akahane K
- Journal Title
  
  Int J Hematol. 82(2)
  
  Pages: 132-136
- Data Source
  KAKENHI-PROJECT-17790694
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Hirose K, Akahane K, Goi K, Sugita K, Nakazawa S. et al.
- Journal Title
  
  International Journal of Hematology 82・2
  
  Pages: 132-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.2005
- Author(s)
  Zhang X, Inukai T, Hirose K, Akahane K, Nemoto A, Takahashi K, Sato H, Kagami K, Goi K, Sugita K, Nakazawa S.
- Journal Title
  
  International Journal of Hematology 82・2
  
  Pages: 132-136
- Data Source
  KAKENHI-PROJECT-16591017
[Journal Article] Oncogenic fusion E2A-HLF sensitize t(17 ; 19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors
- Author(s)
  Zhang X, Inukai T, Hirose K, Akahane K, Kuroda I, et al
- Journal Title
  
  Leukemia
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Journal Article] BCR-ABL regulates death receptor expression for TNF-related apoptosis-inducing ligand(TRAIL) in Philadelphia chromosome-positive leukemia
- Author(s)
  Kuroda I, Inukai T, Akahane K, Hirose K, et al
- Journal Title
  
  Oncogene
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356
[Patent] 胃がん細胞の増殖抑制剤、胃がんの腫瘍形成抑制剤、　　　　　　胃がんを治療するための医薬、及び薬効予測方法2021
- Inventor(s)
  犬飼岳史, 渡辺敦, 三宅邦夫, 赤羽弘資
- Industrial Property Rights Holder
  国立大学法人山梨大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-116120
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] BCP-ALL細胞株のinotuzumab ozogamicin感受性におけるCD22陽性率の意義2023
- Author(s)
  笠井慎, 赤羽弘資, 玉井望雅, 加賀美恵子, 小松千亜紀, 清河信敬, Nguyen TT, 後藤裕明, 峯岸正好, 稲葉俊哉, 岩本彰太郎, 合井久美子, 犬飼岳史
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24298
[Presentation] Ph陽性ALLにおけるインテグリンα6の発現誘導を介するラミニン接着へのBCR::ABL1の関与2023
- Author(s)
  高橋和也, Nguyen TT, 玉井望雅, 原間大輔, 笠井慎, 赤羽弘資, 合井久美子, 加賀美恵子, 小松千亜紀, 犬飼岳史
- Organizer
  第65回日本小児血液がん学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24298
[Presentation] TKI-resistance in a human Ph+ leukemia model with T315I-containing compound mutations of BCR::ABL12023
- Author(s)
  Nguyen Thao TT, Tamai Minori, Harama Daisuke, Kagami Keiko, Komatsu Chiaki, Kasai Shin, Akahane Koushi, Goi Kumiko, Inukai Takeshi
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24298
[Presentation] p210 and p190 BCR::ABL1 induce different gene expression profiles in the artificial Philadelphia chromosome-positive leukemias created by CRISPR/Cas9 system2022
- Author(s)
  Tamai Minori, Nguyen Thao, Komatsu Chiaki, Kagami Keiko, Kasai Shin, Harama Daisuke, Akahane Koshi, Goi Kumiko, Inukai Takeshi
- Organizer
  第64回日本小児血液がん学会
- Data Source
  KAKENHI-PROJECT-23K24298
[Presentation] Establishment of a human acute lymphoblastic leukemia model with relapse-specific mutation of the TP53 gene using the prime editing system2022
- Author(s)
  Nguyen Thao, Tamai Minori, Inaba Toshiya, Nagamachi Akiko, Kagami Keiko, Harama Daisuke, Kasai Shin, Akahane Koshi, Goi Kumiko, Inukai Takeshi
- Organizer
  第64回日本小児血液がん学会
- Data Source
  KAKENHI-PROJECT-23K24298
[Presentation] Associations of NR3C1 mutations and glucocorticoid resistance in BCP-ALL cell lines2021
- Author(s)
  玉井望雅, 笠井慎, タオグエン, 加賀美恵子, 渡邊敦, 赤羽弘資, 矢ヶ崎英晃, 合井久美子, 三宅邦夫, 後藤裕明, 峯岸正好, 岩本彰太郎, 犬飼岳史
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Introduction of relapsed ALL-specific mutation in NT5C2 into lymphoid leukemia model by CRISPR/Cas92021
- Author(s)
  Nguyen Thao, Tamai Minori, Harama Daisuke, Kagami Keiko, Kasai Shin, Watanabe Atsushi, Akahane Koshi, Goi Kumiko, Inukai Takeshi
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] ゲノム編集技術を用いた再発難治ALLモデル2021
- Author(s)
  赤羽弘資
- Organizer
  第63回日本小児血液・がん学会
- Data Source
  KAKENHI-PROJECT-19K08833
[Presentation] TKIs suppress the laminin adhesion of Ph+ALL2021
- Author(s)
  高橋和也, 佐藤広樹, 齋藤衣子, 渡邊敦, 杣津晋平, 赤羽弘資, 合井久美子, 中村誠, 古市嘉行, 根本篤, 加賀美恵子, グエンタオ, 杉田完爾, 犬飼岳史
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Establishment of thiopurine-resistant acute lymphoblastic human lymphoid leukemia models acquiring relapse-specific mutations in the PRPS1 gene using CRISPR/Cas9 system2021
- Author(s)
  Nguyen Thao, Tamai Minori, Harama Daisuke, Kagami Keiko, Kasai Shin, Watanabe Atsushi, Akahane Koshi, Goi Kumiko, Inukai Takeshi
- Organizer
  第63回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Disruption of TP53 by CRISPR/Cas9 system induces multiagent resistance in BCP-ALL cell lines2020
- Author(s)
  Koshi Akahane, Atsushi Watanabe, Nguyen Thi Thu Thao, Keiko Kagami, Masako Abe, Shin Kasai, Daisuke Harama, Kumiko Goi, Takeshi Inukai
- Organizer
  第82回日本血液学会
- Data Source
  KAKENHI-PROJECT-19K08833
[Presentation] Prevalence of MEF2D fusions in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cell lines.2019
- Author(s)
  Akahane K, Inukai T, et al.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Methylation status of asparaginase synthetase (ASNS) gene in childhood T-cell acute lymphoblastic leukemia (T-ALL).2019
- Author(s)
  Akahane K, Inukai T, et al.
- Organizer
  第61回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03615
[Presentation] Anti-leukemic Activity of the TYK2 selective inhibitor NDI-031301 in T-cell Acute Lymphoblastic Leukemia2016
- Author(s)
  Koshi Akahane, Zhaodong Li, Julia Etchin, Alla Berezovskaya, Evisa Gjini, Craig E. Masse, Wenyan Miao, Jennifer Rocnik, Rosana Kapeller, Jeremy R. Greenwood, Hong Tiv, Takaomi Sanda, David M. Weinstock and A. Thomas Look
- Organizer
  58th ASH annual meeting
- Place of Presentation
  San Diego （USA）
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10019
[Presentation] Activity of the TYK2 selective inhibitor NDI-031301 in T-cell Acute Lymphoblastic Leukemia2016
- Author(s)
  Koshi Akahane,, Julia Etchin, Zhaodong Li, Alla Berezovskaya, Craig E. Masse, Wenyan Miao, Jennifer Rocnik, Rosana Kapeller, Takaomi Sanda, David M. Weinstock and A. Thomas Look
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K10019
[Presentation] BCR-ABL regulates death receptor expression for TNF-related apoptosis-inducing ligand(TRAIL) inPhiladelphia chromosome-positive leukemia2011
- Author(s)
  Kuroda I, Inukai T, Akahane K, HiroseK, et al
- Organizer
  53th American Society of Hematology Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2011-12-11
- Data Source
  KAKENHI-PROJECT-21591356
[Presentation] 急性リンパ性白血病におけるCD33遺伝子プロモーターの解析2010
- Author(s)
  杣津晋平、赤羽弘資、加賀美恵子、本名浩子、渡邊敦、根本篤、宇野佳奈子、合井久美子、杉田完爾、犬飼岳史
- Organizer
  第52回日本小児血液学会
- Place of Presentation
  大阪
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-21790976
[Presentation] 17;19転座に由来するE2A-HLF融合転写因子による急性リンパ性白血病でのCD33発現誘導の機序2009
- Author(s)
  赤羽弘資、犬飼岳史、廣瀬衣子、黒田格、根本篤、加賀美恵子、合井久美子、杉田完爾
- Organizer
  第51回日本小児血液学会
- Place of Presentation
  浦安
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21790976
[Presentation] T細胞型急性リンパ性白血病のTRAIL耐性へのTRAIL受容体DR4/DR5遺伝子のメチル化とプロモーター活性の関与2009
- Author(s)
  赤羽弘資,犬飼岳史,廣瀬衣子,黒田格, ほか
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21591356
[Presentation] 17;19転座に由来するE2A-HLF融合転写因子による急性リンパ性白血病でのCD33発現誘導の機序2009
- Author(s)
  赤羽弘資
- Organizer
  第51回日本小児血液学会
- Place of Presentation
  東京ベイホテル東急
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21790976
[Presentation] BCR-ABLはPh1陽性白血病細胞のTRAILに対するdeath受容体の発現に関与する2009
- Author(s)
  黒田格,犬飼岳史,張暁春,廣瀬衣子,赤羽弘資, ほか
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21591356
[Presentation] Philadelphia染色体陽性白血病細胞におけるImatinibによる小胞体ストレス誘導作用とTRAIL感受性の検討2009
- Author(s)
  張暁春,犬飼岳史,黒田格,赤羽弘資,廣瀬衣子, ほか
- Organizer
  第51回日本小児血液学会総会
- Place of Presentation
  幕張
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21591356

1. INUKAI Takeshi (30293450)

# of Collaborated Projects: 6 results

# of Collaborated Products: 45 results
2. HONNA Hiroko (50377537)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. GOI Kumiko (70324192)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
4. KURODA Itaru (30402051)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
5. HIROSE Kinuko (70436880)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. 原間大輔 (10774078)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
7. NAKAZAWA Shinpei (90090034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. SUGITA Kanji (60138055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 渡邊敦 (30610498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
10. 篠原珠緒 (80747452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 玉井望雅 (90747453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
12. SIVASUNDARAM Karnan

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. YAMAUCHI Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. MIYAKE Kunio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 早川文彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 坂口公祥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 太田明伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 吉村健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 芦原英司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 戸田侑紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 滝田順子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 長町安希子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 伊藤悦朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 照井君典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 土岐力

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 高折晃史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 進藤岳郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 仲一仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AKAHANE Koshi 赤羽 弘資

AKAHANE KOSHI 赤羽 弘資

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予後不良なTCF3::HLF陽性急性リンパ性白血病の抗がん剤耐性を克服する治療の開発Principal Investigator

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難治性急性リンパ性白血病に対するプレシジョン・メディシンを目指した多分野融合研究

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Involvement of TP53 mutations in chemoresistance of B-precursor acute lymphoblastic leukemiaPrincipal Investigator

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Integrated study aiming at development of precision medicine for poor prognostic acute lymphoblastic leukemia

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Development of novel therapeutic strategy targeting TYK2 for T-cell acute lymphoblastic leukemiaPrincipal Investigator

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The analysis of CD33 antigens expressed in acute lymphoblastic leukemiaPrincipal Investigator

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Clinical significance of cytotoxic factor-mediated graft-versus-leukemia effect against high-risk childhood leukemia

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The analysis of myeloid antigens expressed in acute lymphoblastic leukemiaPrincipal Investigator

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細胞傷害因子の移植片対白血病効果における意義と臨床応用に向けた研究

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小児急性リンパ性白血病における感染を契機にした自然退縮の機序の解明Principal Investigator

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Establishment of new-therapy and analysis of mechanisms for resistance to apoptosis in poor-prognostic childhood leukemia

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Anti-leukemic activity of cytotoxic ligands against poor-prognostic childhood leukemia

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[Journal Article] Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia2024

Author(s)

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AKAHANE Koshi 赤羽弘資

AKAHANE KOSHI 赤羽弘資

[Journal Article] BCL6 inhibition ameliorates resistance to ruxolitinib in <i>CRLF2</i>-rearranged acute lymphoblastic leukemia2022