Sadakata Tetsushi 定方哲史

… Alternative Names

SADAKATA Tetsushi 定方哲史

定方哲史サダカタテツシ

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Researcher Number	90391961
Other IDs
Affiliation (Current)	2025: 群馬大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 群馬大学, 大学院医学系研究科, 准教授 2015 – 2016: 群馬大学, テニュアトラック普及推進室, 講師 2011 – 2014: 群馬大学, 先端科学研究指導者育成ユニット, 助教 2012: 群馬大学, 先端科学研究指導者育成ユニット, 助教 2010: The Institute of Physical and Chemical Research, 分子神経形成研究チーム, 研究員 … More 2009 – 2010: The Institute of Physical and Chemical Research, 分子神経形成研究チーム, 基礎科学特別研究員 2007: The Institute of Physical and Chemical Research, 分子神経形成研究チーム, 基礎科学特別研究員 2006: 独立行政法人理化学研究所, 分子神経形成研究チーム, 基礎科学特別研究員 2005: 独立行政法人理化学研究所, 分子神経形成研究チーム, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 46010:Neuroscience-general-related / Biological Sciences / Basic Section 49010:Pathological biochemistry-related / Transformative Research Areas, Section (III) / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Neuroscience in general Except Principal Investigator Basic Section 46010:Neuroscience-general-related / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator CAPS2 / 分泌 / 自閉症 / autism / tremor / ARF / trafficking / exocytosis / BDNF / 母乳 … More / 抗体 / IgG / ミクログリア / 神経 / cerebellum / エクソソーム / 統御性T細胞 / オリゴデンドロサイト前駆細胞 / 再髄鞘化 / 大脳白質梗塞 / 血管内皮細胞 / iPS細胞 / Nav1.6 / ARF5 / ARF4 / 本態性振戦 / SNP / Semaphorin 4C / Synaptotagmin I / PHYHIPL / 振戦 / Tremor / CAPS / CAPS1 / NT-3 / CADPS2 … More Except Principal Investigator 有芯小胞 / CAPS2 / CAPSタンパク質 / 分泌障害 / 開口放出 / アミラーゼ / 分泌顆粒 / Cadps2 / 腺房細胞 / 膵外分泌 / ドーパミン / 中脳黒質緻密部 / 中脳被蓋野 / 慢性膵炎 / 膵腺房細胞 / エキソサイトーシス / 分泌小胞 / CAPS2/CADPS2 / 有芯性分泌小胞 / 発達障害 / 自閉症 / 海馬シナプス / 長期増強 / 分泌 / BDNF / トランスゴルジ網trans-Golgi / small GTPase Arf4/5 / GABA作動性 / 脳由来神経脳栄養因子 / 抑制性シナプス / GABA / 不安行動 / トランスゴルジ輸送 / 脳由来神経栄養因子 Less

The role of CAPS in the activity-dependent dense-core vesicle exocytosis: function and impairment
- Principal Investigator
  
  古市貞一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Tokyo University of Science
Analysis of the effects of microglia on the developing brainPrincipal Investigator
- Principal Investigator
  
  定方哲史
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Gunma University
The Effect of Breast Milk on Brain Development via MicrogliaPrincipal Investigator
- Principal Investigator
  
  定方哲史
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Gunma University
Fundamental research for the development of therapeutic strategies for cerebral white matter infarction using iPS cellsHost Researcher
- Principal Investigator
  
  定方哲史
- Host Researcher
  
  定方哲史
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Gunma University
神経細胞におけるクラスII ARFの膜輸送機構の解明Principal Investigator
- Principal Investigator
  
  定方哲史
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Gunma University
有芯小胞トラフィッキング異常による精神・神経疾患モデルマウスの解析Principal Investigator
- Principal Investigator
  
  定方哲史
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Analyses of class II ARF family proteinsPrincipal Investigator
- Principal Investigator
  
  Sadakata Tetsushi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Gunma University
広汎性発達障害モデルマウスを用いた発症メカニズムの解明Principal Investigator
- Principal Investigator
  
  定方哲史
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Analyses of the function of CAPS family proteins in vivoPrincipal Investigator
- Principal Investigator
  
  SADAKATA Tetsushi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Gunma University
Analysis of CAPS2 gene functionPrincipal Investigator
- Principal Investigator
  
  SADAKATA Tetsushi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The Institute of Physical and Chemical Research
Regulatory mechanism and cellular dynamics of exocytosis of BDNF-containing secretory vesicles by CAPS2
- Principal Investigator
  
  FURUICHI Tei-Ichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The Institute of Physical and Chemical Research
脳由来神経栄養因子(BDNF)の分泌に関わるタンパク質CAPS2の解析Principal Investigator
- Principal Investigator
  
  定方哲史
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research

[Book] 「ゴルジ体における有芯小胞の生合成とCAPS タンパク質の役割」実験医学(Experimental Medicine)2012
- Author(s)
  定方哲史、篠田陽、古市貞一生体の科学
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23700454
[Book] 自閉症の発症要因と動物モデル2012
- Author(s)
  篠田陽、定方哲史、三島百合子、古市貞一
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23700454
[Book] 「自閉症の発症要因と動物モデル」実験医学(Experimental Medicine)2012
- Author(s)
  篠田陽、定方哲史、三島百合子、古市貞一実験医学(Experimental Medicine)
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23700454
[Book] 実験医学2012
- Author(s)
  篠田陽、定方哲史、三島百合子、古市貞一
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-23110524
[Book] 「自閉症感受性候補遺伝子CAPS2/CADPS2における遺伝子多型とノックアウトマウスの行動障害」医学のあゆみ2011
- Author(s)
  定方哲史、古市貞一
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-23700454
[Book] 医学のあゆみ2011
- Author(s)
  定方哲史、古市貞一
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PUBLICLY-23110524
[Book] 自閉症支援のすべて2011
- Author(s)
  定方哲史
- Publisher
  日本文化科学社
- Data Source
  KAKENHI-PUBLICLY-23110524
[Book] 自閉症の感受性候補遺伝子と動物モデル(Vol.20No.4)2010
- Author(s)
  篠田陽、定方哲史、林周宏、古市貞一
- Publisher
  脳と精神の医学(新興医学出版社)
- Data Source
  KAKENHI-PROJECT-20300134
[Book] 有芯小胞の分泌制御因子CAPS2と自閉症感受性(Vol.28No.5)2010
- Author(s)
  定方哲史、篠田陽、林周宏、古市貞一
- Publisher
  実験医学増刊号(羊土社)
- Data Source
  KAKENHI-PROJECT-20300134
[Book] CADPS2分子精神医学(Vol8No.2)2008
- Author(s)
  定方哲史、古市貞一
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-20300134
[Book] 自閉症の遺伝要因とCAPS2遺伝子実験医学増刊号(Vol.26No.12)2008
- Author(s)
  定方哲史、篠田陽、古市貞一
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Maternal immunoglobulin G affects brain development of mouse offspring.2024
- Author(s)
  Sadakata M, Fujii K, Kaneko R, Hosoya E, Sugimoto H, Kawabata-Iwakawa R, Kasamatsu T, Hongo S, Koshidaka Y, Takase A, Iijima T, Takao K, Sadakata T.
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 21(1) Issue: 1 Pages: 1-20
- DOI
  10.1186/s12974-024-03100-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H05611
[Journal Article] Transplanted human iPSC-derived vascular endothelial cells promote functional recovery by recruitment of regulatory T cells to ischemic white matter in the brain2023
- Author(s)
  Xu Bin、Shimauchi-Ohtaki Hiroya、Yoshimoto Yuhei、Sadakata Tetsushi、Ishizaki Yasuki
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 20 Issue: 1 Pages: 1-13
- DOI
  10.1186/s12974-023-02694-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H05611, KAKENHI-PROJECT-23K23977, KAKENHI-PROJECT-21F21114
[Journal Article] Loss of CAPS2/Cadps2 leads to exocrine pancreatic cell injury and intracellular accumulation of secretory granules in mice2022
- Author(s)
  Sato Y、Tsuyusaki M、Takahashi-Iwanaga H、Fujisawa R、Masamune A、Hamada S、Matsumoto R、Tanaka Y、Kakuta Y、Yamaguchi-Kabata Y、Furuse T、Wakana S、Shimura T、Kobayashi R、Shinoda Y、Goitsuka R、Maezawa S、Sadakata T、Sano Y、Furuichi T
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 9 Pages: 1-18
- DOI
  10.3389/fmolb.2022.1040237
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07236, KAKENHI-PROJECT-22K06447, KAKENHI-PROJECT-21H02372, KAKENHI-PUBLICLY-21H05611, KAKENHI-PROJECT-23K23977
[Journal Article] Absence of thyroid hormone induced delayed dendritic arborization in mouse primary hippocampal neurons through insufficient expression of brain-derived neurotrophic factor.2021
- Author(s)
  Hiroyuki Yajima, Izuki Amano, Sumiyasu Ishii, Tetsushi Sadakata, Wataru Miyazaki, Yusuke Takatsuru, Noriyuki Koibuchi.
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 12 Pages: 1-13
- DOI
  10.3389/fendo.2021.629100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06900, KAKENHI-PROJECT-20K23265, KAKENHI-PROJECT-19K16486, KAKENHI-PROJECT-21K15340
[Journal Article] The Ser19Stop single nucleotide polymorphism (SNP) of human PHYHIPL affects the cerebellum in mice.2021
- Author(s)
  Hisako Sugimoto, Takuro Horii, Jun-Na Hirota, Yoshitake Sano, Yo Shinoda, Ayumu Konno, Hirokazu Hirai, Yasuki Ishizaki, Hajime Hirase, Izuho Hatada, Teiichi Furuichi, Tetsushi Sadakata.
- Journal Title
  
  Molecular Brain
  
  Volume: 52 Issue: 1 Pages: 1-9
- DOI
  10.1186/s13041-021-00766-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06900, KAKENHI-PROJECT-19K06899
[Journal Article] CAPS1 is involved in hippocampal synaptic plasticity and hippocampus-associated learning.2021
- Author(s)
  Chiaki Ishii, Natsumi Shibano, Mio Yamazaki, Tomoki Arima, Yuna Kato, Yuki Ishii, Yo Shinoda, Yugo Fukazawa, Tetsushi Sadakata, Yoshitake Sano, Teiichi Furuichi.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1-15
- DOI
  10.1038/s41598-021-88009-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06900, KAKENHI-PUBLICLY-20H05058, KAKENHI-PROJECT-19H03323
[Journal Article] Nav1.6の軸索起始部への輸送異常と本態性振戦2021
- Author(s)
  定方哲史
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 39
- Data Source
  KAKENHI-PROJECT-19K06900
[Journal Article] The physiological role of Homer2a and its novel short isoform, Homer2e, in NMDA receptor-mediated apoptosis in cerebellar granule cells2021
- Author(s)
  Furuichi Teiichi、Muto Yuko、Sadakata Tetsushi、Sato Yumi、Hayashi Kanehiro、Shiraishi-Yamaguchi Yoko、Shinoda Yo
- Journal Title
  
  Molecular Brain
  
  Volume: 14 Issue: 1 Pages: 1-11
- DOI
  10.1186/s13041-021-00804-8
- Data Source
  KAKENHI-PROJECT-19K06900
[Journal Article] CAPS2 deficiency impairs the release of the social peptide, oxytocin, as well as oxytocin-associated social behavior.2021
- Author(s)
  Shuhei Fujima, Ryosuke Yamaga, Haruka Minami, Shota Mizuno, Yo Shinoda, Tetsushi Sadakata, Manabu Abe, Kenji Sakimura, Yoshitake Sano, Teiichi Furuichi.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: － Issue: 20 Pages: 4524-4535
- DOI
  10.1523/jneurosci.3240-20.2021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06900
[Journal Article] Deletion of Class II ADP-Ribosylation Factors in Mice Causes Tremor by the Nav1.6 Loss in Cerebellar Purkinje Cell Axon Initial Segments.2019
- Author(s)
  Hosoi N, Shibasaki K, Hosono M, Konno A, Shinoda Y, Kiyonari H, Inoue K, Muramatsu SI, Ishizaki Y, Hirai H, Furuichi T, Sadakata T
- Journal Title
  
  J Neurosci
  
  Volume: 39(32) Issue: 32 Pages: 6339-6353
- DOI
  10.1523/jneurosci.2002-18.2019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07103, KAKENHI-PROJECT-19K06899, KAKENHI-PROJECT-19K06900, KAKENHI-PROJECT-18K19418, KAKENHI-PLANNED-15H05934, KAKENHI-PROJECT-18H02522, KAKENHI-PROJECT-18H03124, KAKENHI-PROJECT-17H03563
[Journal Article] Interaction of Ca2+-dependent activator protein for secretion 1 (CAPS1) with septin family proteins in mouse brain2016
- Author(s)
  Hosono M, Shinoda Y, Hirano T, Ishizaki Y, Furuichi T and Sadakata T
- Journal Title
  
  Neurosci. Lett.
  
  Volume: 617 Pages: 232-235
- DOI
  10.1016/j.neulet.2016.02.035
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08192, KAKENHI-PROJECT-25430061, KAKENHI-PROJECT-15K14356, KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-26290026
[Journal Article] Analysis of gene expression in Ca2+-dependent activator protein for secretion 2 (Cadps2) knockout cerebellum using GeneChip and KEGG pathways2016
- Author(s)
  Sadakata T, Shinoda Y, Ishizaki Y, Furuichi T.
- Journal Title
  
  Neuroscience Letters
  
  Volume: 639 Pages: 88-93
- DOI
  10.1016/j.neulet.2016.12.068
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-26290026, KAKENHI-PROJECT-25430061, KAKENHI-PROJECT-15K14356, KAKENHI-PROJECT-15K08192, KAKENHI-PROJECT-17H03563
[Journal Article] 自閉症関連遺伝子CAPS2の解析2016
- Author(s)
  定方哲史
- Journal Title
  
  生化学
  
  Volume: 88 Pages: 501-505
- NAID
  40020948554
- Data Source
  KAKENHI-PROJECT-25430061
[Journal Article] Lack of stress responses to long-term effects of corticosterone in Caps2 knockout mice.2015
- Author(s)
  Yuriko Mishima, Yo Shinoda, Tetsushi Sadakata, Masami Kojima, Shigeharu Wakana, Teiichi Furuichi.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 1-6
- DOI
  10.1038/srep08932
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25110707, KAKENHI-PROJECT-25860169, KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-26290026, KAKENHI-PROJECT-25430061, KAKENHI-PROJECT-15K14356
[Journal Article] Age-dependent redistribution and hypersialylation of the central myelin paranodal loop membrane protein Opalin in the mouse brain.2014
- Author(s)
  Yumi Sato, Fumio Yoshikawa, Tetsushi Sadakata, Yo Shinoda, Michinori Koebis, Teiichi Furuichi.
- Journal Title
  
  Neurosci Letter
  
  Volume: 581 Pages: 14-19
- DOI
  10.1016/j.neulet.2014.08.017
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25110707, KAKENHI-PROJECT-25430061, KAKENHI-PROJECT-25860169, KAKENHI-PROJECT-26290026
[Journal Article] Axonal localization of Ca2+-dependent activator protein for secretion 2 is critical for subcellular locality of brain-derived neurotrophic factor and neurotrophin-3 release affecting proper development of postnatal mouse cerebellum.2014
- Author(s)
  Sadakata T, Kakegawa W, Shinoda Y, Hosono M, Katoh-Semba R, Sekine Y, Sato Y, Saruta C, Ishizaki Y, Yuzaki M, Kojima M, Furuichi T.
- Journal Title
  
  PLoS One.
  
  Volume: 9(6) Issue: 6 Pages: 1-10
- DOI
  10.1371/journal.pone.0099524
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23240053, KAKENHI-PUBLICLY-25110707, KAKENHI-PROJECT-25430061, KAKENHI-PROJECT-25860169, KAKENHI-PUBLICLY-26117515, KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-26290026, KAKENHI-PROJECT-26293042
[Journal Article] Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF and causes autistic-like behavior in mice2013
- Author(s)
  Tetsushi Sadakata, Yo Shinoda, Megumi Oka, Yukiko Sekine, Yumi Sato, Chihiro Saruta, Hideki Miwa, Mika Tanaka, Shigeyoshi Itohara, Teiichi Furuichi
- Journal Title
  
  Proceedings of the National Academy ofSciences of the United States of America
  
  Volume: 109 (51) Pages: 21104-21109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700454
[Journal Article] Animal models of autism spectrum disorder (ASD): a synaptic-level approach to autistic-like behavior in mice.2013
- Author(s)
  Shinoda Y, Sadakata T, Furuichi T.
- Journal Title
  
  Exp Anim.
  
  Volume: 62(2) Pages: 71-8
- NAID
  10031163545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430061
[Journal Article] Mouse models of mutations and variations in autism spectrum disorder-associated genes : mice expressing caps2/cadps2 copy number and alternative splicing variants2013
- Author(s)
  Sadakata T, Shinoda Y, Sato A, Iguchi H, Ishii C, Matsuo M, Yamaga R, Furuichi T
- Journal Title
  
  Int J Environ Res Public Health
  
  Volume: 10 Issue: 12 Pages: 6335-6353
- DOI
  10.3390/ijerph10126335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240062, KAKENHI-PROJECT-23300137, KAKENHI-PUBLICLY-25110707, KAKENHI-PROJECT-25430061
[Journal Article] Autistic-like behavioral phenotypes in a mouse model with copy number variation of the CAPS2/CADPS2 gene2013
- Author(s)
  Sadakata T, Shinoda Y, Oka M, Sekine Y, Furuichi T.
- Journal Title
  
  FEBS Lett
  
  Volume: 587 Issue: 1 Pages: 54-59
- DOI
  10.1016/j.febslet.2012.10.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240062, KAKENHI-PROJECT-23300137, KAKENHI-PUBLICLY-25110707, KAKENHI-PROJECT-25430061, KAKENHI-PROJECT-25860169
[Journal Article] CAPS1 deficiency perturbs dense-core vesicle trafficking and Golgi structure and reduces presynaptic release probability in the mouse brain.2013
- Author(s)
  Sadakata T, Kakegawa W, Shinoda Y, Hosono M, Katoh-Semba R, Sekine Y, Sato Y, Tanaka M, Iwasato T, Itohara S, Furuyama K, Kawaguchi Y, Ishizaki Y, Yuzaki M, Furuichi T.
- Journal Title
  
  J Neurosci.
  
  Volume: 33 Issue: 44 Pages: 17326-17334
- DOI
  10.1523/jneurosci.2777-13.2013
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22115009, KAKENHI-PLANNED-23110009, KAKENHI-PROJECT-23240053, KAKENHI-PROJECT-23240062, KAKENHI-PROJECT-23300137, KAKENHI-PROJECT-23689012, KAKENHI-PUBLICLY-25110707, KAKENHI-PUBLICLY-25122704, KAKENHI-PROJECT-25430061, KAKENHI-PROJECT-25860169
[Journal Article] Autistic-like behavioral phenotypes in a mouse model with copy number variation of the CAPS2/CADPS2 gene2013
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  FEBS Letter.
  
  Volume: 587 Pages: 54-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700454
[Journal Article] Animal Models of Autism Spectrum Disorder (ASD): A Synaptic-Level Approach to Autistic-Like Behavior in Mice2013
- Author(s)
  Yo Shinoda, Tetsushi Sadakata, Teiichi Furuichi
- Journal Title
  
  Experimental Animals.
  
  Volume: 62 Pages: 71-78
- NAID
  10031163545
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25110707
[Journal Article] Autistic-like behavioral phenotypes in a mouse model with copy number variation of the CAPS2/CADPS2 gene2013
- Author(s)
  Tetsushi Sadakata, Yo Shinoda, Megumi Oka, Yukiko Sekine, Teiichi Furuichi
- Journal Title
  
  FEBS Letter
  
  Volume: 587(1) Pages: 54-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700454
[Journal Article] Autistic-like behavioral phenotypes in a mouse model with copy number variation of the CAPS2/CADPS2 gene2013
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  FEBS Letter.
  
  Volume: 587 Pages: 54-59
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23110524
[Journal Article] Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF and causes autistic-like behavior in mice.2012
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America.
  
  Volume: 109 Pages: 21104-21109
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23110524
[Journal Article] Calcium-dependent activator protein for secretion 2 (CAPS2) interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking.2012
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  FEBS Journal.
  
  Volume: 279 Pages: 384-394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700454
[Journal Article] Calcium-dependent activator protein for secretion 2 (CAPS2) interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking2012
- Author(s)
  Tetsushi Sadakata, Yukiko Sekine, Megumi Oka, Makoto Itakura, Masami Takahashi, Teiichi Furuichi
- Journal Title
  
  FEBS Journal
  
  Volume: 279(3) Pages: 384-394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700454
[Journal Article] Calcium-dependent activator protein for secretion 2 (CAPS2) interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking.2012
- Author(s)
  Tetsushi Sadakata, Yukiko Sekine, Megumi Oka, Makoto Itakura, Masami Takahashi, Teiichi Furuichi.
- Journal Title
  
  FEBS Journal.
  
  Volume: 279(3) Pages: 384-394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700454
[Journal Article] Calcium-dependent activator protein for secretion 2 (CAPS2) interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking2012
- Author(s)
  Sadakata T, Sekine Y, Oka M, Itakura M, Takahashi M, Furuichi T
- Journal Title
  
  FEBS Journal
  
  Volume: 279 Pages: 384-394
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23110524
[Journal Article] Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF and causes autistic-like behavior in mice.2012
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America.
  
  Volume: 109 Pages: 21104-21109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700454
[Journal Article] Calcium-dependent activator protein for secretion 2 (CAPS2) interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking.2012
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  FEBS Journal.
  
  Volume: 279 Pages: 384-394
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23110524
[Journal Article] Calcium-dependent activator protein for secretion 2 (CAPS2) promotes BDNF secretion and is critical for the development of GABAergic interneuron network.2011
- Author(s)
  Shinoda Y., Sadakata T., Nakao K., Katoh-Semba R., Kinameri E., Furuya A., Yanagawa Y., Hirase H., Furuichi T.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 108
  
  Pages: 373-378
- NAID
  120002771000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Calcium-dependent activator protein for secretion 2 (CAPS2) promotes BDNF secretion and is critical for the development of GABAergic interneuron network2011
- Author(s)
  Shinoda Y, Sadakata T, Nakao K, Katoh-Semba R, Kinameri E, Furuya A, Yanagawa Y, Hirase H, Furuichi T
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 108 Pages: 373-378
- NAID
  120002771000
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23110524
[Journal Article] Systematizing and cloning of genes involved in the cerebellar cortex circuit development.2011
- Author(s)
  Furuichi T., Shiraishi-Yamaguchi Y., Sato A., Sadakata T., Huang J., Shinoda Y., Hayashi K., Mishima Y., Tomomura M., Nishibe H., Yoshikawa F.
- Journal Title
  
  Neurochem Res (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Systematizing and cloning of genes involved in the cerebellar cortex circuit development2011
- Author(s)
  Furuchi T, Shiraishi Y, Sato A, Sadakata T, Huang J, Shinoda Y, Hayashi K, Mishima Y, Tomomura M, Yoshikawa F
- Journal Title
  
  Neurochemical Research
  
  Volume: 36 Pages: 1241-1262
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23110524
[Journal Article] Phase advance of the light-dark cycle perturbs diurnal rhythms of brain-derived neurotrophic factor and neurotrophin-3 levels, which reduces synaptophysin-positive presynaptic terminals in the cortex of juvenile rats2011
- Author(s)
  Hamatake M, Miyazaki N, Sudo K, Matsuda M, Sadakata T, Furuya A, Ichisaka S, Hata Y, Nakagawa C, Nagata K, Furuichi T, Katoh-Semba R
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 21478-21487
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23110524
[Journal Article] Interaction of CAPS1 with the class II ARF small GTPases is required for dense-core vesicle trafficking in the trans-Golgi network.2010
- Author(s)
  Tetsushi Sadakata, Yo Shinoda, Yukiko Sekine, Chihiro Saruta, Makoto Itakura, Masami Takahashi, Teiichi Furuichi.
- Journal Title
  
  Journal of Biological Chemistry. 285(49)
  
  Pages: 38710-38719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700421
[Journal Article] Interaction of CAPS1 with the class II ARF small GTPases is required for dense-core vesicle trafficking in the trans-Golgi network.2010
- Author(s)
  Tetsusahi Sadakata
- Journal Title
  
  Journal of Biological Chemistry.
  
  Volume: 285(49) Pages: 38710-38719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700421
[Journal Article] Ca2+-dependent activator protein for secretion 2 and autistic-like phenotypes2010
- Author(s)
  Tetsushi Sadakata, Teiichi Furuichi.
- Journal Title
  
  Neuroscience Research. 67(3)
  
  Pages: 197-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700421
[Journal Article] 有芯小胞の分泌制御因子CAPS2と自閉症感受性2010
- Author(s)
  定方哲史
- Journal Title
  
  実験医学 (印刷中)
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Interaction of Calcium-dependent Activator Protein for Secretionl (CAPS1) with the Class II ADP-ribosylation Factor Small GTPases Is Required for Dense-core Vesicle Trafficking in the trans}-Golgi Network2010
- Author(s)
  Sadakata Tetsushi
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 285 Pages: 38710-38719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Interaction of CAPS1 with the class II Arf small GTPases is required for dense-core vesicle trafficking in the trans-Golgi network.2010
- Author(s)
  Sadakata T., Shinoda Y., Sekine Y., Saruta C., Itakura M., Takahashi M., Furuichi T.
- Journal Title
  
  J.Biol.Chem 285
  
  Pages: 38710-38719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Phospholipase D family member 4, a transmembrane glycoprotein with no phospholipase D activity, expression in spleen and early postnatal microglia.2010
- Author(s)
  Yoshikawa F., Banno Y., Otani Y., Yamaguchi Y., Nagakura-Takagi Y., Morita N., Sato Y., Saruta C., Nishibe H., Sadakata T., Shinoda Y., Hayashi K., Mishima Y., Baba H., Furuichi T.
- Journal Title
  
  PLoS ONE 5(11)
- NAID
  120002753724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Expression of the IP3R1 promoter-driven nls-lacZ transgene in Purkinje cell parasagittal arrays of developing mouse cerebellum.2010
- Author(s)
  Furutama D., Morita N., Takano R., Sekine Y., Sadakata T., Shinoda Y., Hayashi K., Mishima Y., Mikoshiba K., Hawkes R., Furuichi T.
- Journal Title
  
  J.Neurosci.Res 88
  
  Pages: 2810-2825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Calcium-dependent activator protein for secretion 2 (CAPS2) promotes BDNF secretion and is critical for the development of GABAergic interneuron network.2010
- Author(s)
  Yo Shinoda, Tetsushi Sadakata, Kazuhito Nakao, Ritsuko Katoh-Semba, Emi Kinameri, Asako Furuya, Yuchio Yanagawa, Hajime Hirase, Teiichi Furuichi.
- Journal Title
  
  Proceedings of the National Academy of Sciences. 108(1)
  
  Pages: 373-378
- NAID
  120002771000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700421
[Journal Article] Ca^<2+>-dependent activator protein for secretion 2 and autistic-like phenotypes.2010
- Author(s)
  Sadakata T., Furuichi T.
- Journal Title
  
  Neurosci Res 67
  
  Pages: 197-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Developmentally-regulated Ca^<2+>-dependent activator protein for secretion 2 (CAPS2) is involved in BDNF secretion and is associated with autism susceptibility.2009
- Author(s)
  Tetsushi Sadakata, Teiichi Furuichi.
- Journal Title
  
  Cerebellum. 8(3)
  
  Pages: 312-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700421
[Journal Article] Response to the letter by Eran et al. (Comment on "Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients")2009
- Author(s)
  Tetsushi Sadakata, Teiichi Furuichi.
- Journal Title
  
  Journal of Clinical Investigation. 119(4)
  
  Pages: 680-681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700421
[Journal Article] Developmentally regulated Ca2+-dependent activator protein for secretion 2 (CAPS2) is involved in BDNF secretion and is associated with autism susceptibility.2009
- Author(s)
  Sadakata T., Furuichi T.
- Journal Title
  
  Cerebellum 8
  
  Pages: 312-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Developmentally regulated Ca^<2+>-dependent activator protein for secretion 2(CAPS2)is involved in BDNF secretion and is associated with autism susceptibility2009
- Author(s)
  定方哲史
- Journal Title
  
  Cerebellum 8巻
  
  Pages: 312-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Developmentally-regulated Ca^<2+>-dependent activator protein for secretion 2(CAPS2)is involved in BDNF secretion and is associated with autism susceptibility2009
- Author(s)
  Tetsusahi Sadakata
- Journal Title
  
  Cerebellum 8(3)
  
  Pages: 312-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700421
[Journal Article] CADPS2と自閉症感受性2009
- Author(s)
  定方哲史
- Journal Title
  
  分子精神医学 9巻, 3号
  
  Pages: 16-22
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] 自閉症の遺伝要因とCAPS2遺伝子2008
- Author(s)
  定方哲史
- Journal Title
  
  実験医学 26巻
  
  Pages: 2015-2023
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Cerebellar Development Transcriptome Database (CDT-DB) : profiling of spatio-temporal gene expression during the postnatal development of mouse cerebellum.2008
- Author(s)
  Sato A., Sekine Y., Saruta C., Nishibe H., Morita N., Sato Y., Sadakata T., Shinoda Y., Kojima T., Furuichi T.
- Journal Title
  
  Neural Networks 21
  
  Pages: 1056-1069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] CADPS22008
- Author(s)
  定方哲史
- Journal Title
  
  分子精神医学 8巻
  
  Pages: 150-151
- Data Source
  KAKENHI-PROJECT-20300134
[Journal Article] Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in neurotrophin release.2007
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  Journal of Neuroscience (in press)
- Data Source
  KAKENHI-PROJECT-17700322
[Journal Article] 有芯小胞分泌関連タンパク質CAPS2研究の展開〜自閉症との関連〜2007
- Author(s)
  定方哲史
- Journal Title
  
  神経化学 46(4)
  
  Pages: 836-843
- NAID
  10020158193
- Data Source
  KAKENHI-PROJECT-17700322
[Journal Article] Autistic-like phenotypes in CADPS2/CAPS2 knockout mice and aberrant CADPS2 splicing in autistic patients.2007
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  Journal of Clinical Investigation (in press)
- Data Source
  KAKENHI-PROJECT-17700322
[Journal Article] Autistic-like phenotypes in Cadps2-knockout mice and aber rant CADPS2 splicing in autistic patients2007
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  J Clin lnvest. 117(4)
  
  Pages: 931-943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17700322
[Journal Article] Tissue Distribution of Ca2+-dependent Activator Protein for Secretion Family Members CAPS1 and CAPS2 in Mice.2007
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  Journal of Histochemisty and Cytochemistry 55(3)
  
  Pages: 301-311
- Data Source
  KAKENHI-PROJECT-17700322
[Journal Article] Alternative splicing variations in mouse CAPS2: differential expression and functional properties of splicing variants2007
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  BMC Neurosci. 8(25)
  
  Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17700322
[Journal Article] Differential distributions of the Ca2+-dependent activator protein for secretion family proteins (CAPS2 and CAPS1) in the mouse brain.2006
- Author(s)
  Sadakata, et al.
- Journal Title
  
  Journal of comparative neurology (in press)
- Data Source
  KAKENHI-PROJECT-17700322
[Journal Article] Identification and mRNA expression of Ogdh, QP-C, and two predicted genes in the postnatal mouse brain.2006
- Author(s)
  Tetsushi Sadakata
- Journal Title
  
  Neuroscience Letter 405(3)
  
  Pages: 217-222
- Data Source
  KAKENHI-PROJECT-17700322
[Journal Article] Phase advance of the light-dark cycle perturbs diurnal rhythms of brain-derived neurotrophic factor and neurotrophin-3 levels, which reduces synaptophysin-positive presynaptic terminals in the cortex of juvenile rats.
- Author(s)
  Hamatake M., Miyazaki N., Sudo K., Matsuda M., Sadakata T., Furuya A., Ichisaka S., Hata Y., Nakagawa C., Nagata K., Furuichi T., Katoh-Semba R.
- Journal Title
  
  J.Biol.Chem (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] Maternal immunoglobulin G affects brain development of mouse offspring2024
- Author(s)
  Mizuki Sadakata, Tetsushi Sadakata
- Organizer
  第13回国際放射線神経生物学会
- Data Source
  KAKENHI-PUBLICLY-21H05611
[Presentation] The Influence of Breast Milk on Brain Development via Microglia2023
- Author(s)
  Mizuki Sadakata, Keizo Takao, Ryosuke Kaneko, Takatoshi Iijima, Tetsushi Sadakata.
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PUBLICLY-21H05611
[Presentation] 母乳に含まれる抗体が仔の脳に及ぼす影響についての解析2023
- Author(s)
  定方瑞樹、定方哲史
- Organizer
  2023年度東日本研究医養成コンソーシアム第13回「夏のリトリート」
- Data Source
  KAKENHI-PUBLICLY-21H05611
[Presentation] 母乳がミクログリアを介して子の脳の発達に与える影響について2022
- Author(s)
  定方哲史
- Organizer
  第5回和光-精神神経懇話会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H05611
[Presentation] 母性因子がミクログリアを介して子の脳の発達に与える影響の解析2022
- Author(s)
  定方哲史、高雄啓三、金子涼輔、飯島崇利
- Organizer
  NEURO2022（第45回日本神経科学大会・第65回日本神経化学会大会・第32回日本神経回路学会大会　合同大会）
- Data Source
  KAKENHI-PROJECT-23K23977
[Presentation] 母性因子がミクログリアを介して子の脳の発達に与える影響の解析2022
- Author(s)
  定方哲史、高雄啓三、金子涼輔、飯島崇利
- Organizer
  NEURO2022（第45回日本神経科学大会・第65回日本神経化学会大会・第32回日本神経回路学会大会　合同大会）
- Data Source
  KAKENHI-PUBLICLY-21H05611
[Presentation] 子の脳の発達に影響を与える母乳の因子について2022
- Author(s)
  定方哲史
- Organizer
  フードテックグランプリ2022
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H05611
[Presentation] 母性因子がミクログリアを介して子の脳の発達に与える影響の解析2022
- Author(s)
  定方瑞樹、高雄啓三、金子涼輔、飯島崇利、定方哲史
- Organizer
  NEURO2022（第45回日本神経科学大会／第65回日本神経化学会大会／第32回日本神経回路学会大会）
- Data Source
  KAKENHI-PUBLICLY-21H05611
[Presentation] 子の脳の発達に影響を与える母乳の因子について2022
- Author(s)
  定方哲史
- Organizer
  産学連携協定締結金融機関等意見交換会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H05611
[Presentation] The Ser19Stop single nucleotide polymorphism (SNP) of human PHYHIPL affects the cerebellum in mice2021
- Author(s)
  Tetsushi Sadakata
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K06900
[Presentation] The Ser19Stop single nucleotide polymorphism (SNP) of human PHYHIPL affects the cerebellum in mice2021
- Author(s)
  Tetsushi Sadakata, Takuro Horii, Jun-na Hirota, Yoshitake Sano, Yo shinoda, Ayumu Konno, Hirokazu Hirai, Yasuki Ishizaki, Hajime Hirase, Izuho Hatada, Teiichi Furuichi, Hisako Sugimoto
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-19K06900
[Presentation] CAPS2のexon3スキップと自閉症2015
- Author(s)
  定方哲史
- Organizer
  BMB2015（第38回日本分子生物学会年会・第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド（兵庫、神戸）
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-25430061
[Presentation] 自閉症モデルマウスを用いた包括的解析2015
- Author(s)
  定方哲史
- Organizer
  第２回生物学的自閉症研究会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2015-07-19
- Invited
- Data Source
  KAKENHI-PROJECT-25430061
[Presentation] 自閉症モデルマウスを用いた発症メカニズムの解明2013
- Author(s)
  定方哲史
- Organizer
  包括的神経グリア研究会2013
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23700454
[Presentation] 自閉症モデルマウスを用いた発症メカニズムの解明2013
- Author(s)
  定方哲史
- Organizer
  平成２５年度生理学研究所研究会
- Place of Presentation
  岡崎
- Invited
- Data Source
  KAKENHI-PUBLICLY-25110707
[Presentation] 自閉症モデルマウスを用いた発症メカニズムの解明2013
- Author(s)
  定方哲史
- Organizer
  包括的神経グリア研究会2013
- Place of Presentation
  浜松
- Invited
- Data Source
  KAKENHI-PUBLICLY-23110524
[Presentation] Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF and causes autistic-like behavior in mice2013
- Author(s)
  Tetsushi Sadakata, Yo Shinoda, Megumi Oka, Yukiko Sekine, Yumi Sato, Chihiro Saruta, Hideki Miwa, Mika Tanaka, Shigeyoshi Itohara, and Teiichi Furuichi.
- Organizer
  43th Annual Meeting of Society for Neuroscience
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-25430061
[Presentation] 自閉症モデルマウスを用いた発症メカニズムの解明2013
- Author(s)
  定方哲史
- Organizer
  平成２５年度生理学研究所研究会
- Place of Presentation
  岡崎
- Invited
- Data Source
  KAKENHI-PROJECT-25430061
[Presentation] CAPS2遺伝子異常による自閉症発症機序の解明2012
- Author(s)
  定方哲史
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23700454
[Presentation] Reduced axonal localization of a Caps2 splice variant impairs polarization of BDNF release and causes autistic-like behavior in mice2012
- Author(s)
  Tetsushi Sadakata
- Organizer
  Japanese Association of Scientists in Singapore (JASS)
- Place of Presentation
  シンガポール
- Invited
- Data Source
  KAKENHI-PUBLICLY-23110524
[Presentation] CAPS2のsplicing異常と自閉症2012
- Author(s)
  定方哲史
- Organizer
  日本生化学会（関東支部）
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-23700454
[Presentation] CAPS2遺伝子異常による自閉症発症機序の解明2012
- Author(s)
  定方哲史
- Organizer
  日本生化学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23700454
[Presentation] CAPS2のsplicing異常と自閉症2012
- Author(s)
  定方哲史、古市貞一
- Organizer
  平成24年度日本生化学会関東支部例会
- Place of Presentation
  前橋
- Year and Date
  2012-06-23
- Data Source
  KAKENHI-PROJECT-23700454
[Presentation] Axonal transport of Caps2 splice variant linked to BDNF coordination of brain circuit development and autism-related behavior in a mouse model2012
- Author(s)
  Tetsushi Sadakata
- Organizer
  北関東医学会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PUBLICLY-23110524
[Presentation] Reduced axonal localization of a Caps2 splice variant impairs polarization of BDNF release and causes autistic-like behavior in mice2012
- Author(s)
  Tetsushi Sadakata
- Organizer
  Japanese Association of Scientists in Singapore (JASS)
- Place of Presentation
  シンガポール
- Invited
- Data Source
  KAKENHI-PROJECT-23700454
[Presentation] CAPS2遺伝子異常による自閉症発症機序の解明2012
- Author(s)
  定方哲史
- Organizer
  日本生化学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PUBLICLY-23110524
[Presentation] CAPS2のsplicing異常と自閉症2012
- Author(s)
  定方哲史
- Organizer
  日本生化学会（関東支部）
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PUBLICLY-23110524
[Presentation] Axonal transport of Caps2 splice variant linked to BDNF coordination of brain circuit development and autism-related behavior in a mouse model2012
- Author(s)
  Tetsushi Sadakata
- Organizer
  北関東医学会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-23700454
[Presentation] CAPS2のsplicing異常と自閉症2011
- Author(s)
  定方哲史
- Organizer
  包括型脳科学研究推進支援ネットワーク・夏のワークショップ
- Place of Presentation
  神戸
- Year and Date
  2011-08-22
- Data Source
  KAKENHI-PUBLICLY-23110524
[Presentation] CAPS2 protein, dense-core vesicle trafficking and autism2011
- Author(s)
  Tetsushi Sadakata
- Organizer
  The 10th JBS Biofrontier Symposium
- Place of Presentation
  福岡
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PUBLICLY-23110524
[Presentation] Reduced axonal transport of a Cadps2 splice variant causes impaired BDNF-mediated brain circuit development and autism-related behavior in a mouse model2011
- Author(s)
  Tetsushi Sadakata, Yo Shinoda, Yukiko Sekine, Megmi Oka, Yumi Sato, Mika Tanaka, Shigeyoshi Itohara, Shigeharu Wakana, and Teiichi Furuichi
- Organizer
  第二回国際放射線神経生物学会大会
- Place of Presentation
  前橋
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-23700454
[Presentation] CAPS2 protein-mediated regulation of dense-core vesicle secretion pathway and susceptibility to developmental disorders2010
- Author(s)
  Tetsushi Sadakata
- Organizer
  東北大学脳科学グローバルCOE・第3回脳神経科学サマーリトリート
- Place of Presentation
  仙台
- Year and Date
  2010-07-31
- Data Source
  KAKENHI-PROJECT-21700421
[Presentation] CAPS2のエクソン3スキップマウスは自閉症様形質を示す2010
- Author(s)
  定方哲史
- Organizer
  第33回日本神経科学大会・第53回日本神経化学会大会・第20回日本神経回路学会大会合同大会(Neuro2010)
- Place of Presentation
  神戸日本
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] CAPS2による有芯小胞分泌と自閉症2010
- Author(s)
  定方哲史
- Organizer
  第27回東北大学脳科学グローバルCOE若手フォーラム
- Place of Presentation
  仙台
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21700421
[Presentation] Autistic-like phenotypes in CAPS2 exon 3-skipped mice2010
- Author(s)
  Sadakata Tetsushi
- Organizer
  18th World Congress on Psychiatric Genetics
- Place of Presentation
  Athens Greece
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] Autistic-like phenotypes in CAPS2 exon-skipped mice2010
- Author(s)
  Tetsushi Sadakata
- Organizer
  XVIIIth World Congress on Psychiatric Genetics
- Place of Presentation
  Athens, Greece
- Data Source
  KAKENHI-PROJECT-21700421
[Presentation] CAPS2のエキソン3スキップマウスは自閉症様形質を示す2010
- Author(s)
  定方哲史
- Organizer
  Neuro 2010
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21700421
[Presentation] Ca^<2+>依存性活性化分泌関連タンパク質CAPS2は正常な脳の発達と行動に必須な役割を果たす2009
- Author(s)
  古市貞一、定方哲史、篠田陽
- Organizer
  第61回日本細胞生物学会大会・シンポジウム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] CAPS and ARFs are associated with dense-core vesicle biogenesis from the Golgi complex2009
- Author(s)
  Tetsushi Sadakata
- Organizer
  The Japan-Korea Conference on Cellular Signaling for Young Scientists
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21700421
[Presentation] CAPS1とクラス||ARFはゴルジ体における有芯小胞の生成に関わる2009
- Author(s)
  Tetsushi Sadakata
- Organizer
  日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21700421
[Presentation] CAPS1とクラスII ARFはゴルジ体における有芯小胞の生成に関わる2009
- Author(s)
  Tetsushi Sadakata
- Organizer
  日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21700421
[Presentation] The functional role of CAPS family proteins in dense-core vesicle trafficking2009
- Author(s)
  Tetsushi Sadakata
- Organizer
  日本神経科学学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21700421
[Presentation] CAPS and ARFs are associated with dense-core vesicle biogenesis from the Golgi complex2009
- Author(s)
  Tetsushi Sadakata
- Organizer
  The Japan-Korea Conference on Cellular Signaling for Youna Scientists
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21700421
[Presentation] CAPS and ARFs are associated with dense-core vesicle biogenesis from the Golgi complex2009
- Author(s)
  定方哲史
- Organizer
  6th Japan-Korea Conference on Cellular Signaling for Young Scientists
- Place of Presentation
  Sasebo Nagasaki
- Year and Date
  2009-11-24
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] CAPS2タンパク質による有芯小胞分泌経路の制御と発達障害の感受性2009
- Author(s)
  古市貞一、定方哲史、篠田陽、仙波りつ子
- Organizer
  第82回日本生化学会大会・シンポジウム
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] ペプチドを含む有芯小胞はゴルジ体よりいかにして生まれるか?2009
- Author(s)
  Tetsushi Sadakata
- Organizer
  日本神経内分泌学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-21700421
[Presentation] CAPS1とクラス2ARFはゴルジ体における有芯小胞の生成に関わる2009
- Author(s)
  定方哲史
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸市(兵庫県)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] ペプチドを含む有芯小胞は Golgi 体よりいかにして生まれるか2009
- Author(s)
  定方哲史
- Organizer
  第36回日本神経内分泌学会
- Place of Presentation
  北九州市(福岡県)
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] 神経回路の発達と機能に必要なCAPS2の遺伝子欠損マウスは社会性相互作用の障害と不安行動の増加を示す2009
- Author(s)
  古市貞一、定方哲史、篠田陽、仙波りつ子
- Organizer
  第32回日本分子生物学会年会・シンポジウム
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] ペプチドを含む有芯小胞はゴルジ体よりいかにして生まれる?2009
- Author(s)
  Tetsushi Sadakata
- Organizer
  日本神経内分泌学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-21700421
[Presentation] The functional analyses of CAPS family proteins2008
- Author(s)
  定方哲史
- Organizer
  第31回日本神経科学大会(Neuroscience 2008)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] CAPS2 function in dense-core vesicle trafficking2008
- Author(s)
  定方哲史
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会(BMB2008)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] CAPS2に依存したBDNF分泌の欠損は自閉症感受性と関連する2008
- Author(s)
  古市貞一、定方哲史、篠田陽
- Organizer
  第31回日本神経科学大会・シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-20300134
[Presentation] 自閉症の発症に関連する遺伝子CAPS2の解析2007
- Author(s)
  定方哲史
- Organizer
  第50回日本神経科学大会第 50回日本神経化学会大会第17回日本神経回路学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17700322
[Presentation] 自閉症関連遺伝子CAPS2
- Author(s)
  定方哲史
- Organizer
  第61回北関東医学会総会
- Place of Presentation
  前橋
- Year and Date
  2014-09-25 – 2014-09-26
- Invited
- Data Source
  KAKENHI-PUBLICLY-25110707
[Presentation] 有芯小胞分泌不全と自閉症
- Author(s)
  定方哲史
- Organizer
  第36回日本生物学的精神医学会・第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-25110707
[Presentation] 自閉症関連遺伝子CAPS2
- Author(s)
  定方哲史
- Organizer
  第61回北関東医学会総会
- Place of Presentation
  前橋
- Year and Date
  2014-09-25 – 2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-25430061
[Presentation] 有芯小胞分泌不全と自閉症
- Author(s)
  定方哲史
- Organizer
  第36回日本生物学的精神医学会・第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-25430061

1. FURUICHI Tei-Ichi (50219094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
2. SHINODA Yo (80403096)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
3. XU BIN

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 前澤創 (90548174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 高雄啓三 (80420397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 飯島崇利 (90383702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. HOSOI Nobutake

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 岩永ひろみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 岩里琢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 柚崎通介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 掛川渉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sadakata Tetsushi 定方 哲史

SADAKATA Tetsushi 定方 哲史

定方 哲史 サダカタ テツシ

Research Projects

Research Products

Co-Researchers

The role of CAPS in the activity-dependent dense-core vesicle exocytosis: function and impairment

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Analysis of the effects of microglia on the developing brainPrincipal Investigator

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The Effect of Breast Milk on Brain Development via MicrogliaPrincipal Investigator

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Fundamental research for the development of therapeutic strategies for cerebral white matter infarction using iPS cellsHost Researcher

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神経細胞におけるクラスII ARFの膜輸送機構の解明Principal Investigator

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有芯小胞トラフィッキング異常による精神・神経疾患モデルマウスの解析Principal Investigator

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Analyses of class II ARF family proteinsPrincipal Investigator

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広汎性発達障害モデルマウスを用いた発症メカニズムの解明Principal Investigator

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Analyses of the function of CAPS family proteins in vivoPrincipal Investigator

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Analysis of CAPS2 gene functionPrincipal Investigator

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Regulatory mechanism and cellular dynamics of exocytosis of BDNF-containing secretory vesicles by CAPS2

Principal Investigator

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脳由来神経栄養因子(BDNF)の分泌に関わるタンパク質CAPS2の解析Principal Investigator

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[Book] 「ゴルジ体における有芯小胞の生合成とCAPS タンパク質の役割」実験医学(Experimental Medicine)2012

Sadakata Tetsushi 定方哲史

SADAKATA Tetsushi 定方哲史

定方哲史サダカタテツシ