MARUYA Shin-ichiro 丸屋信一郎

Researcher Number	90396408
Affiliation (based on the past Project Information) *help	2008 – 2012: International University of Health and Welfare, 大学病院, 講師 2007: Hirosaki University, 医学部附属病院, 助教 2005 – 2006: 弘前大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Otorhinolaryngology Except Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator 頭頸部癌 / 頭頸部扁平上皮癌 / インテグリン / simvastatin / 腺様嚢胞癌 / thymidylate synthase / thymidilate synthase / siRNA / アポトーシス / apoptosis … More Except Principal Investigator … More 外有毛細胞 / prestin / 運動能 / パッチクランプ法 / キャパシタンス / ソノポレーション法 / コルチ器 / 内耳再生 / 内耳外有毛細胞 / 蝸牛増幅機構 / siRNA / lipid raft / 脂質 / コレステロール / 聴覚 / 翻訳後修飾機 / 内耳 / 細胞内シグナル伝達系 / Lipid raft / 細胞骨格 / G蛋白 Less

Regulation of the OHC cytoskeleton induced by lipid raft.-Effects of cholesterol alterations on hearing-
- Principal Investigator
  
  KAKEHTA Seiji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamagata University
Prestin翻訳後修飾機構の解明-OHC運動能自己修復による内耳再生への挑戦-
- Principal Investigator
  
  欠畑誠治
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hirosaki University
Lipid raftはOHC情報伝達を調節する-運動能における脂質の機能解明-
- Principal Investigator
  
  欠畑誠治
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hirosaki University
Function of thymidylate synthase as a therapeutic target in head and neck cancerPrincipal Investigator
- Principal Investigator
  
  MARUYA Shinichiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  International University of Health and Welfare
  Hirosaki University
Direct functional analysis of prestin transfected inner ear using invivo patch method
- Principal Investigator
  
  KAKEHATA Seiji
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hirosaki University
intact OHCを用いたsiRNAによる至適prestin発現密度の直接解析
- Principal Investigator
  
  新川秀一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hirosaki University
ソノポレーション法によるinvivoコルチ器へのprestin遺伝子導入
- Principal Investigator
  
  KAKEHATA Seiji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hirosaki University
頭頚部癌における新たな治療標的としてのインテグリン細胞接着分子機能の解明Principal Investigator
- Principal Investigator
  
  丸屋信一郎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hirosaki University

All 2009 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] Differential expression of topoisometase IIα protein in salivary carcinomas : histogenetic and prognostic implications2009
- Author(s)
  Maruya S, Shirasaki T, Nagaki T, Kakehata S, Kurotaki H, et.al.
- Journal Title
  
  BMC Cancer (In press)(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791182
[Journal Article] Differential expression of topoisomerase IIα protein in salivary gland carcinomas: histogenetic and prognostic implications.2009
- Author(s)
  Maruya S, Shirasaki T, Nagaki T, Kakehata S, Kurotaki H, Mizukami H, Shinkawa H.
- Journal Title
  
  BMC Cancer (in press)
- Data Source
  KAKENHI-PROJECT-19791182
[Journal Article] Effects of small interfering RNA targeting thymidylate synthase on survival of ACC3 cells from salivary adenoid cystic carcinoma.2008
- Author(s)
  Shirasaki T, Maruya S, Mizukami H, Kakehata S, Kurotaki H, Yagihashi S, Shinkawa H.
- Journal Title
  
  BMC Cancer (in press)
- Data Source
  KAKENHI-PROJECT-19791182
[Journal Article] Autologous serum eardrops therapy with a chitin membrane for closing tympanic membrane for closing tympanic membrane perforations2008
- Author(s)
  Kakehata S, Hirose Y, Kitani R, Futai K Maruya S, Ishii K, Shinkawa H
- Journal Title
  
  Otol Neurotol 29
  
  Pages: 791-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791182
[Journal Article] Effects of small interfering RNA targeting thymidylate synthase on survival of ACC3 cells from salivary adenoid cystic carcinoma2008
- Author(s)
  Shirasaki T, Maruya S, Mizukami H, Kakehata S, Kurotaki H, et.al.
- Journal Title
  
  BMC Cancer (In press)(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791182
[Journal Article] Autologous serum eardrops therapy with a chitin membrane for closing tympanic membrane perforations2008
- Author(s)
  Kakehata S, Hirose Y, Kitani R, Futai K, Maruya S, Ishii K, Shinkawa H.
- Journal Title
  
  Otol Neurotol 29
  
  Pages: 791-795
- Data Source
  KAKENHI-PROJECT-19791182
[Journal Article] Simvastatin inactivates β1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells.2007
- Author(s)
  Takeda I, Maruya S, Shirasaki T, Mizukami H, Takahata T, Myers JN, Kakehata S, Yagihashi S, Shinkawa H.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 890-899
- Data Source
  KAKENHI-PROJECT-19791182
[Journal Article] Simvastatin inactivates β1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells2007
- Author(s)
  Takeda I, Maruya S, et. al.
- Journal Title
  
  Cancer Science 98
  
  Pages: 890-899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791182
[Journal Article] (corresponding author) Developmental expression of the outer hair cell motor, prestin, in the mouse2007
- Author(s)
  Abe T, Kakehata S, Kitani R, Maruya SI, Navaratnam D, Santos-Sacchi J, Shinkawa H
- Journal Title
  
  J Membr Biol 215
  
  Pages: 49-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390454
[Journal Article] Simvastatin inactivates β1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells2007
- Author(s)
  Takeda I, Maruya S, et al.
- Journal Title
  
  Cancer Science (In press)
- Data Source
  KAKENHI-PROJECT-17791152
[Journal Article] Developmental expression of the outer hair cell moter prestin in the mouse2007
- Author(s)
  Abe T, Kakehata S, Kitani R, Maruya S, Navaratnam D, Santos-Sacchi J, Shinkawa H.
- Journal Title
  
  L Membr Biol 215
  
  Pages: 49-56
- Data Source
  KAKENHI-PROJECT-19791182
[Journal Article] Localization of dopamine receptor subtypes in the rat spinal ganglion2006
- Author(s)
  Inoue T, Matsubara A, Maruya S, et al.
- Journal Title
  
  Neuroscience Letters 399
  
  Pages: 226-229
- Data Source
  KAKENHI-PROJECT-17791152
[Journal Article] Implication of methylation patterns of cancer genes in salivary gland tumors.2006
- Author(s)
  Williams MD, Chakravarti N, Kies MS, Maruya S, et al.
- Journal Title
  
  Clinical Cancer Research 12
  
  Pages: 7353-7358
- Data Source
  KAKENHI-PROJECT-17791152
[Journal Article] Two cases of salivary gland carcinoma treated with intra-arterial concomitant chemoradiation of cisplatin and docetazel2006
- Author(s)
  Maruya S, Namba A, et al.
- Journal Title
  
  International Journal of Clinical Oncology 11
  
  Pages: 403-406
- Data Source
  KAKENHI-PROJECT-17791152
[Journal Article] Differential Expression of p63 Isotypes (ΔN and TA) in Salivary Gland Neoplasms : Biological and Diagnostic Implications.2005
- Author(s)
  Maruya S et al.
- Journal Title
  
  Human Pathology 36
  
  Pages: 821-827
- Data Source
  KAKENHI-PROJECT-17791152
[Journal Article] ICAM-5 (telencephalin) gene expression in head and neck squamous carcinoma tumorigenesis and perineural invasion.2005
- Author(s)
  Maruya S et al.
- Journal Title
  
  Oral Oncology 41
  
  Pages: 580-588
- Data Source
  KAKENHI-PROJECT-17791152
[Journal Article] 頭頸部腫瘍における遺伝子発現異常の解析2005
- Author(s)
  丸屋信一郎
- Journal Title
  
  病理と臨床 23
  
  Pages: 1223-1227
- Data Source
  KAKENHI-PROJECT-17791152
[Presentation] DirectEffects of Cholesterol and Mβcd On OuterHair Cell Motility and Capacitance2008
- Author(s)
  Kitani R, Kakehata S, Murakoshi M, WadaH, Maruya S, Abe T, Shinkawa H
- Organizer
  31st MidWinter Meeting of Association for Research in Otolaryngology
- Place of Presentation
  Phoenix, Arizona, USA
- Data Source
  KAKENHI-PROJECT-18390454
[Presentation] 頭頸部癌における遺残例、再発・転移例に対するTS-1の使用経験2007
- Author(s)
  白崎隆、丸屋信一郎, 他
- Organizer
  第45回日本癌治療学会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-19791182

1. KAKEHATA Seiji (90261619)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
2. WADA Hiroshi (30111264)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. UENO Shinya (00312158)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. NAMBA Atsushi (50361027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KITANI Rei (80436047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. MURAKOSHI Michio (70570901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 新川秀一 (90125584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 二井一則 (40431457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MARUYA Shin-ichiro 丸屋 信一郎

Research Projects

Research Products

Co-Researchers

Regulation of the OHC cytoskeleton induced by lipid raft.-Effects of cholesterol alterations on hearing-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prestin翻訳後修飾機構の解明-OHC運動能自己修復による内耳再生への挑戦-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Lipid raftはOHC情報伝達を調節する-運動能における脂質の機能解明-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Function of thymidylate synthase as a therapeutic target in head and neck cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Direct functional analysis of prestin transfected inner ear using invivo patch method

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

intact OHCを用いたsiRNAによる至適prestin発現密度の直接解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ソノポレーション法によるinvivoコルチ器へのprestin遺伝子導入

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

頭頚部癌における新たな治療標的としてのインテグリン細胞接着分子機能の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differential expression of topoisometase IIα protein in salivary carcinomas : histogenetic and prognostic implications2009

Author(s)

Journal Title

Data Source

[Journal Article] Differential expression of topoisomerase IIα protein in salivary gland carcinomas: histogenetic and prognostic implications.2009

Author(s)

Journal Title

Data Source

[Journal Article] Effects of small interfering RNA targeting thymidylate synthase on survival of ACC3 cells from salivary adenoid cystic carcinoma.2008

Author(s)

Journal Title

Data Source

[Journal Article] Autologous serum eardrops therapy with a chitin membrane for closing tympanic membrane for closing tympanic membrane perforations2008

Author(s)

Journal Title

Data Source

[Journal Article] Effects of small interfering RNA targeting thymidylate synthase on survival of ACC3 cells from salivary adenoid cystic carcinoma2008

Author(s)

Journal Title

Data Source

[Journal Article] Autologous serum eardrops therapy with a chitin membrane for closing tympanic membrane perforations2008

Author(s)

Journal Title

Data Source

[Journal Article] Simvastatin inactivates β1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells.2007

Author(s)

Journal Title

Data Source

MARUYA Shin-ichiro 丸屋信一郎