Uruno Akira 宇留野晃

… Alternative Names

URUNO Akira 宇留野晃

宇留野晃ウルノアキラ

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Researcher Number	90396474
Other IDs	https://orcid.org/0000-0002-9224-0161
External Links
Affiliation (Current)	2025: 東北大学, 東北メディカル・メガバンク機構, 非常勤講師
Affiliation (based on the past Project Information) *help	2017 – 2023: 東北大学, 東北メディカル・メガバンク機構, 准教授 2017: 東北大学, 医学系研究科, 准教授 2017: 東北大学, 大学病院, 講師 2016 – 2017: 東北大学, 医学系研究科, 講師 2012 – 2016: 東北大学, 医学(系)研究科(研究院), 講師 … More 2014 – 2015: 東北大学, 大学院医学系研究科, 講師 2010 – 2011: 東北大学, 大学院・医学系研究科, 助教 2007: 東北大, 大学病院 2006: 東北大学, 病院・医員 2005 – 2006: 東北大学, 病院, 医員 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Kidney internal medicine / Basic Section 59040:Nutrition science and health science-related / Basic Section 49010:Pathological biochemistry-related / Applied health science / General medical chemistry Except Principal Investigator Neurosurgery / Earth and planetary science and related fields / Pathological medical chemistry / Endocrinology / General medical chemistry
Keywords	Principal Investigator Nrf2 / 酸化ストレス / 糖尿病 / アルツハイマー病 / グルタチオン / 神経炎症 / 膵β細胞 / Keap1-Nrf2システム / ミクログリア / Keap1-Nrf2系 … More / アミノ酸 / 神経科学 / 認知症 / CNC因子 / C. elegans / 線虫 / skn-1 / Nrf1 / 代謝制御 / 視床下部 / Keap1 / レプチン抵抗性 / インスリン抵抗性 / 代謝学 / セレノシステイン / 肥満 / 血管内皮細胞 / 腎血流 / スタチン系製剤 / 肝細胞増殖因子 / 血管新生 … More Except Principal Investigator endothelial cells / retinoid / angiogenesis / retinoic acid receptor / all-trans retinoic acid / 酸化ストレス / 超音波併用薬剤送達 / Chemical Surgery / 中枢神経系 / 薬剤送達 / 神経膠腫 / CED / 脳内薬物動態 / ドラックデリバリー / 脳内薬物代謝経路 / 有機物 / 分布 / 質量分析 / イメージング質量分析計 / アミノ酸 / イメージング / 質量分析計 / 有機分子 / 隕石 / 生体分子 / 遺伝子改変 / 糖尿病 / 膵β細胞 / Nrf2 / 受容体 / 動脈硬化 / 血管内皮増殖因子 / 血管内皮細胞 / レチノイド / 血管新生 / レチノイン酸受容体 / レチノイン酸 / 個体発生 / がん / オートファジー / 病態代謝 / 細胞分化 / 炎症 / 転写制御 Less

Nrf2 and Neuroinflammation in Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  宇留野晃
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tohoku University
Glutathione regulations in Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Uruno Akira
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tohoku University
Roles of oxidative stress in metabolic regulations(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Uruno Akira
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
Role of Nrf2 in Alzheimer's disease with diabetes mellitusPrincipal Investigator
- Principal Investigator
  
  Uruno Akira
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Tohoku University
Investigation on imaging of distribution of organic molecules in meteorites
- Principal Investigator
  
  Furukawa Yoshihiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Earth and planetary science and related fields
- Research Institution
  Tohoku University
Basic Research for Development of Chemical Surgery
- Principal Investigator
  
  Saito Ryuta
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Tohoku University
The role of Nrf2 in oxidative stress-mediated insulin resistancePrincipal Investigator
- Principal Investigator
  
  Akira Uruno
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
The role of Nrf2 in pancreatic beta-cells; a study of new pancreatic beta-cell specific Nrf2 activation model mice
- Principal Investigator
  
  Yoko Yagishita
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
Roles of stress-responsive transcription factors in health and disease
- Principal Investigator
  
  YAMAMOTO Masayuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
The role of Keap1-Nrf2 system in obesity-induced pancreatic beta-cell dysfunctionsPrincipal Investigator
- Principal Investigator
  
  URUNO Akira
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
The role of Keap1-Nrf2 system in oxidative stress response of pancreatic β-cellsPrincipal Investigator
- Principal Investigator
  
  URUNO Akira
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
レチノイン酸による血管内皮におけるPI3キナーゼ調節機構の解明Principal Investigator
- Principal Investigator
  
  宇留野晃
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tohoku University
EFFECTS OF ALL-TRANS RETINOIC ACID AND RETINOIDS ON ANGIOGENESIS
- Principal Investigator
  
  SUGAWARA Akira
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Tohoku University
腎微小循環における肝細胞増殖因子の病態生理学的意義の解明Principal Investigator
- Principal Investigator
  
  宇留野晃
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tohoku University

[Book] Molecular Nutrition and Diabetes2015
- Author(s)
  Yagishita Y, Uruno A and Yamamoto M.
- Total Pages
  400
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-26893008
[Book] Molecular Nutrition and Diabetes. Section 3, 34. Nrf2-mediated gene regulations and glucose homeostasis2015
- Author(s)
  Yoko Yagishita, Akira Uruno, Masayuki Yamamoto
- Publisher
  Elsevier.B.V.
- Data Source
  KAKENHI-PROJECT-26893008
[Book] Molecular Nutrition and Diabetes, 1st Edition.2015
- Author(s)
  Yagishita Y, Uruno A, Yamamoto M
- Total Pages
  400
- Publisher
  Elsevier Science B.V.
- Data Source
  KAKENHI-PROJECT-26460383
[Book] レチノイン酸受容体(RAR)によるPOMC遺伝子発現における転写因子NeuroD1およびTpitの役割, 平成22年度総括・分担研究報告書2011
- Author(s)
  宇留野晃、菅原明、松田謙、工藤正孝、岩崎泰正、伊藤貞嘉
- Data Source
  KAKENHI-PROJECT-22890014
[Book] レチノイドX受容体(RXR)がACTH分泌・POMC遺伝子発現に及ぼす影響に関する検討, 平成21年度総括・分担研究報告書2010
- Author(s)
  宇留野晃、菅原明、岩崎泰正、伊藤貞嘉
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] Combined Fat Mass and Fat-free Mass Indices and Lung Function Among Japanese Population: The Tohoku Medical Megabank Community-based Cohort Study2024
- Author(s)
  Takase Masato、Uruno Akira et al.
- Journal Title
  
  Journal of Epidemiology
  
  Volume: 34 Issue: 3 Pages: 119-128
- DOI
  10.2188/jea.JE20220355
- ISSN
  0917-5040, 1349-9092
- Year and Date
  2024-03-05
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-19K10637
[Journal Article] The KEAP1-NRF2 system and neurodegenerative diseases2023
- Author(s)
  Uruno Akira、Yamamoto Masayuki
- Journal Title
  
  Antioxidants & Redox Signaling
- DOI
  10.1089/ars.2023.0005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07352
[Journal Article] Reduced glutathione level in the aqueous humor of patients with primary open-angle glaucoma and normal-tension glaucoma2023
- Author(s)
  Sato Kota、Saigusa Daisuke、Kokubun Taiki、Fujioka Amane、Feng Qiwei、Saito Ritsumi、Uruno Akira、Matsukawa Naomi、Ohno-Oishi Michiko、Kunikata Hiroshi、Yokoyama Yu、Yasuda Masayuki、Himori Noriko、Omodaka Kazuko、Tsuda Satoru、Maekawa Shigeto、Yamamoto Masayuki、Nakazawa Toru
- Journal Title
  
  npj Aging
  
  Volume: 9 Issue: 1 Pages: 28-28
- DOI
  10.1038/s41514-023-00124-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-23K27316
[Journal Article] Improving the Signal Intensity of Cryosections Using a Conductive Adhesive Film in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging2023
- Author(s)
  Saigusa Daisuke、Saito Ritsumi、Kawamoto Komei、Uruno Akira、Kano Kuniyuki、Shimma Shuichi、Aoki Junken、Yamamoto Masayuki、Kawamoto Tadafumi
- Journal Title
  
  Mass Spectrometry
  
  Volume: 12 Issue: 1 Pages: A0137-A0137
- DOI
  10.5702/massspectrometry.A0137
- ISSN
  2186-5116, 2187-137X
- URL
  https://localhost/en/publications/95d13124-f19e-4f01-9d88-0e00c67c2610
- Year and Date
  2023-12-12
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-23K27316
[Journal Article] The Association of Lung Function and Carotid Intima-Media Thickness in a Japanese Population: The Tohoku Medical Megabank Community-Based Cohort Study2023
- Author(s)
  Masato Takase, Mitsuhiro Yamada, Tomohiro Nakamura, Naoki Nakaya, Mana Kogure, Rieko Hatanaka, Kumi Nakaya, Ikumi Kanno, Kotaro Nochioka, Naho Tsuchiya, Takumi Hirata, Yohei Hamanaka, Junichi Sugawara, Tomoko Kobayashi, Nobuo Fuse, Akira Uruno, Eiichi N Kodama, Shinichi Kuriyama, Ichiro Tsuji, Atsushi Hozawa
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 30 Issue: 8 Pages: 1022-1044
- DOI
  10.5551/jat.63826
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2023-08-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10637, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-23K21501, KAKENHI-PROJECT-21K19366, KAKENHI-PROJECT-23H05465
[Journal Article] Design and Progress of Child Health Assessments at Community Support Centers in the Birth and Three-Generation Cohort Study of the Tohoku Medical Megabank Project2023
- Author(s)
  Kobayashi T, Kobayashi M, Minegishi N, Kikuya M, Obara T, Ishikuro M, Yamanaka C, Onuma T, Murakami K, Ueno F, Noda A, Uruno A, Sugawara J, Suzuki K, Kodama EN, Hamanaka Y, Tsuchiya M, Kogure M, Nakaya N, Taira M, Sakurai-Yageta M, Tamahara T, Kawashima J, Goto M, Otsuki A, Shimizu R,Ogishima A,1, Hashizume H, et al.
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 259 Issue: 2 Pages: 93-105
- DOI
  10.1620/tjem.2022.J103
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03555, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-23K21501, KAKENHI-PROJECT-21H03537, KAKENHI-PROJECT-23H05465
[Journal Article] Associations between the Combined Fat Mass Index and Fat-Free Mass Index with Carotid Intima-Media Thickness in a Japanese Population: The Tohoku Medical Megabank Community-Based Cohort Study2023
- Author(s)
  Takase Masato、Nakamura Tomohiro、Nakaya Naoki、Kogure Mana、Hatanaka Rieko、Nakaya Kumi、Kanno Ikumi、Nochioka Kotaro、Tsuchiya Naho、Hirata Takumi、Hamanaka Yohei、Sugawara Junichi、Suzuki Kichiya、Fuse Nobuo、Uruno Akira、N Kodama Eiichi、Kuriyama Shinichi、Tsuji Ichiro、Kure Shigeo、Hozawa Atsushi
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 30 Issue: 3 Pages: 255-273
- DOI
  10.5551/jat.63523
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2023-03-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-19K10637
[Journal Article] Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice2023
- Author(s)
  Shimizu Ritsuko、Hirano Ikuo、Hasegawa Atsushi、Suzuki Mikiko、Otsuki Akihito、Taguchi Keiko、Katsuoka Fumiki、Uruno Akira、Suzuki Norio、Yumoto Akane、Okada Risa、Shirakawa Masaki、Shiba Dai、Takahashi Satoru、Suzuki Takafumi、Yamamoto Masayuki
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 875-875
- DOI
  10.1038/s42003-023-05251-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19396, KAKENHI-PROJECT-22K15376, KAKENHI-PROJECT-23KK0137, KAKENHI-PROJECT-23K06409, KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-23K21372
[Journal Article] Association between lung function and hypertension and home hypertension in a Japanese population: the Tohoku Medical Megabank Community-Based Cohort Study2023
- Author(s)
  Masato Takase, Mitsuhiro Yamada, Tomohiro Nakamura, Naoki Nakaya, Mana Kogure, Rieko Hatanaka, Kumi Nakaya, Ippei Chiba, Ikumi Kanno, Kotaro Nochioka, Naho Tsuchiya, Takumi Hirata, Yohei Hamanaka, Junichi Sugawara, Tomoko Kobayashi, Nobuo Fuse, Akira Uruno, Eiichi N Kodama, Shinichi Kuriyama, Ichiro Tsuji, et al.
- Journal Title
  
  Journal of hypertension
  
  Volume: 41 Pages: 443-452
- DOI
  10.1097/hjh.0000000000003356
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10637, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-23K21501
[Journal Article] Nrf2 deficiency deteriorates diabetic kidney disease in Akita model mice2022
- Author(s)
  Liu Yexin、Uruno Akira、Saito Ritsumi、Matsukawa Naomi、Hishinuma Eiji、Saigusa Daisuke、Liu Hong、Yamamoto Masayuki
- Journal Title
  
  Redox Biology
  
  Volume: 58 Pages: 102525-102525
- DOI
  10.1016/j.redox.2022.102525
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-20K07352
[Journal Article] Halofuginone micelle nanoparticles eradicate Nrf2-activated lung adenocarcinoma without systemic toxicity2022
- Author(s)
  Panda Harit、Suzuki Mikiko、Naito Mitsuru、Saito Ritsumi、Wen Huaichun、Baird Liam、Uruno Akira、Miyata Kanjiro、Yamamoto Masayuki
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 187 Pages: 92-104
- DOI
  10.1016/j.freeradbiomed.2022.05.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-20K07352
[Journal Article] Genome-wide Association Study of Axial Length in Population-based Cohorts in Japan2022
- Author(s)
  Fuse N, Sakurai M, Motoike IN., Kojima K, Takai-Igarashi T, et al.
- Journal Title
  
  Ophthalmology Science
  
  Volume: 2 Issue: 1 Pages: 100113-100113
- DOI
  10.1016/j.xops.2022.100113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09927, KAKENHI-PROJECT-19H03555, KAKENHI-PROJECT-20K07352
[Journal Article] Maternal Baseline Characteristics and Perinatal Outcomes: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study2022
- Author(s)
  Sugawara, J.,et al., Koshiba, S., et al., Yamamoto, M.（合計32名、本研究者は21番目）
- Journal Title
  
  Journal of Epidemiology
  
  Volume: 32 Issue: 2 Pages: 69-79
- DOI
  10.2188/jea.JE20200338
- NAID
  130008157950
- ISSN
  0917-5040, 1349-9092
- Year and Date
  2022-02-05
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-19H03701, KAKENHI-PROJECT-17K01011, KAKENHI-PROJECT-18K11545, KAKENHI-PROJECT-21H03537
[Journal Article] Consideration of the reference value and number of measurements of the urinary sodium-to-potassium ratio based on the prevalence of untreated home hypertension: TMM Cohort Study2022
- Author(s)
  Kogure Mana、Uruno Akira et al.
- Journal Title
  
  Hypertension Research
  
  Volume: 45 Issue: 5 Pages: 866-875
- DOI
  10.1038/s41440-021-00843-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07352
[Journal Article] A Pilot Study for Return of Individual Pharmacogenomic Results to Population-Based Cohort Study Participants2022
- Author(s)
  Ohneda K, Hiratsuka M, Kawame H et al.
- Journal Title
  
  JMA Journal
  
  Volume: 5 Issue: 2 Pages: 177-189
- DOI
  10.31662/jmaj.2021-0156
- ISSN
  2433-328X, 2433-3298
- Year and Date
  2022-04-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06816, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-23K21501, KAKENHI-PROJECT-21H03537
[Journal Article] Nrf2 plays a critical role in the metabolic response during and after spaceflight2021
- Author(s)
  Uruno A、Saigusa D、Suzuki T、Yumoto A、Nakamura T、Matsukawa N、Yamazaki T、Saito R、Taguchi K、Suzuki M、Suzuki N、Otsuki A、Katsuoka F、Hishinuma E、Okada R、Koshiba S、Tomioka Y、Shimizu R、Shirakawa M、Kensler TW.、Shiba D、Yamamoto M
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1381-1381
- DOI
  10.1038/s42003-021-02904-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H03555, KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-23K21372
[Journal Article] Novel method for evaluating the health condition of mice in space through a video downlink2021
- Author(s)
  YUMOTO Akane、KOKUBO Toshiaki、IZUMI Ryutaro、SHIMOMURA Michihiko、FUNATSU Osamu、TADA Motoki N.、OTA-MURAKAMI Naoko、IINO Kayoko、SHIRAKAWA Masaki、MIZUNO Hiroyasu、KUDO Takashi、TAKAHASHI Satoru、SUZUKI Takafumi、URUNO Akira、YAMAMOTO Masayuki、SHIBA Dai
- Journal Title
  
  Exp. Anim.
  
  Volume: 70 Issue: 2 Pages: 236-244
- DOI
  10.1538/expanim.20-0102
- NAID
  130008037417
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-19H05649
[Journal Article] Multiple measurements of the urinary sodium-to-potassium ratio strongly related home hypertension: TMM Cohort Study.2020
- Author(s)
  Kogure M, Hirata T, Nakaya N, Tsuchiya N, Nakamura T, Narita A, Miyagawa K, Koshimizu H, Obara T, Metoki H, Uruno A, Kikuya M, Sugawara J, Kuriyama S, Tsuji I, Kure S, Hozawa A.
- Journal Title
  
  Hypertens Res
  
  Volume: 43 Issue: 1 Pages: 62-71
- DOI
  10.1038/s41440-019-0335-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-16KK0195
[Journal Article] Nrf2 contributes to the weight gain of mice during space travel2020
- Author(s)
  Suzuki, T., et al., Koshiba, S. et al., Yamamoto, M.（合計37名、本研究者は18番目）
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 496-496
- DOI
  10.1038/s42003-020-01227-2
- NAID
  120007161347
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-20K09474, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02614, KAKENHI-PROJECT-18H02621, KAKENHI-ORGANIZER-15H05935, KAKENHI-WRAPUP-20H05615
[Journal Article] Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals2019
- Author(s)
  Yamaguchi-Kabata, Y.,（途中略）,Koshiba, S., （途中略）, Tohoku Medical Megabank Project Study Group.（合計１9名、本研究者は５番目）
- Journal Title
  
  Hum. Genet.
  
  Volume: 印刷中 Issue: 4 Pages: 389-409
- DOI
  10.1007/s00439-019-01998-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-18K11545, KAKENHI-PROJECT-16K00385, KAKENHI-PROJECT-16K08638, KAKENHI-PUBLICLY-19H05200, KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-16KK0195
[Journal Article] Nrf2 represses the onset of type 1 diabetes in non-obese diabetic mice.2019
- Author(s)
  Yagishita Y, Uruno A, Chartoumpekis DV, Kensler TW, Yamamoto M.
- Journal Title
  
  J Endocrinol
  
  Volume: 未定 Issue: 3 Pages: 403-416
- DOI
  10.1530/joe-18-0355
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-18K19417, KAKENHI-PLANNED-26111002
[Journal Article] Metabolomic changes in the mouse retina after optic nerve injury.2018
- Author(s)
  Sato K, Saigusa D, Saito R, Fujioka A, Nakagawa Y, Nishiguchi KM, Kokubun T, Motoike IN, Maruyama K, Omodaka K, Shiga Y, Uruno A, Koshiba S, Yamamoto M, Nakazawa T.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 11930-11930
- DOI
  10.1038/s41598-018-30464-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-17K08233, KAKENHI-PROJECT-17K11475, KAKENHI-PROJECT-17K16958
[Journal Article] Development and evaluation of ultrasound-facilitated drug delivery device2018
- Author(s)
  Inoue Kenji、Sato Aya、Saito Ryuta、Wenting Jia、Okuno Saori、Ohashi Yuji、Kamada Kei、Yoshikawa Akira、Tominaga Teiji
- Journal Title
  
  Japanese Journal of Applied Physics
  
  Volume: 57 Issue: 11S Pages: 11UD07-11UD07
- DOI
  10.7567/jjap.57.11ud07
- NAID
  210000149801
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04299
[Journal Article] Metabolomic Analysis of Mouse Brain after a Transient Middle Cerebral Artery Occlusion by Mass Spectrometry Imaging2018
- Author(s)
  Abe T, Niizuma K, Kanoke A, Saigusa D, Saito R, Uruno A, Fujimura M, Yamamoto M, Tominaga T.
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 58 Issue: 9 Pages: 384-392
- DOI
  10.2176/nmc.oa.2018-0054
- NAID
  130007484209
- ISSN
  0470-8105, 1349-8029
- URL
  https://pure.teikyo.jp/en/publications/803c8578-3ab3-4996-bfa3-ad1c0e6cbe91
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K08233
[Journal Article] High glucose stimulates expression of aldosterone synthase (CYP11B2) and secretion of aldosterone in human adrenal cells2017
- Author(s)
  Shimada Hiroki、Kogure Naotaka、Noro Erika、Kudo Masataka、Sugawara Kaori、Sato Ikuko、Shimizu Kyoko、Kobayashi Makoto、Suzuki Dai、Parvin Rehana、Saito-Ito Takako、Uruno Akira、Saito-Hakoda Akiko、Rainey William E.、Ito Sadayoshi、Yokoyama Atsushi、Sugawara Akira
- Journal Title
  
  FEBS Open Bio
  
  Volume: 7 Issue: 9 Pages: 1410-1421
- DOI
  10.1002/2211-5463.12277
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08606, KAKENHI-PROJECT-16K09600, KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-16H03252, KAKENHI-PROJECT-15K09420, KAKENHI-PROJECT-16K15492
[Journal Article] The novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice.2017
- Author(s)
  Higashi C, Kawaji A, Tsuda N, Hayashi M, Saito R, Yagishita Y, Suzuki T, Uruno A, Nakamura M, Nakao K, Furusako S, Yamamoto M.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 802 Pages: 76-84
- DOI
  10.1016/j.ejphar.2017.02.044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-16K19046, KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K15590
[Journal Article] Nrf2-mediated regulation of skeletal muscle glycogen metabolism.2016
- Author(s)
  Uruno A, Yagishita Y, Katsuoka F, Kitajima Y, Nunomiya A, Nagatomi R, Pi J, Biswal SS, Yamamoto M.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 36
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460383
[Journal Article] Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism.2016
- Author(s)
  Uruno A, Yagishita Y, Katsuoka F, Kitajima Y, Nunomiya A, Nagatomi R, Pi J, Biswal SS, Yamamoto M.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 36 Issue: 11 Pages: 1655-1672
- DOI
  10.1128/mcb.01095-15
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16J00431, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-16K19046, KAKENHI-PROJECT-15K16486
[Journal Article] Nrf2-mediated regulation of skeletal muscle glycogen metabolism.2016
- Author(s)
  Uruno A, Yagishita Y, Katsuoka F, Kitajima Y, Nunomiya A, Nagatomi R, Pi J, Biswal S and Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 36
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26893008
[Journal Article] Effects of RXR agonists on cell proliferation/apoptosis and ACTH secretion/Pomc expression2015
- Author(s)
  Saito-Hakoda A, Uruno A, Yokoyama A, Shimizu K, Parvin R, Kudo M, Saito-Ito T, Sato I, Kogure N, Suzuki D, Shimada H, Yoshikawa T, Fujiwara I, Kagechika H, Iwasaki Y, Kure S, Ito S, Sugawara A
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 12 Pages: e0141960-e0141960
- DOI
  10.1371/journal.pone.0141960
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09420, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-25461381, KAKENHI-PROJECT-26830041
[Journal Article] The Keap1-Nrf2 system and diabetes mellitus.2015
- Author(s)
  Uruno A, Yagishita Y, Yamamoto M.
- Journal Title
  
  Arch Biochem Biophys.
  
  Volume: 566 Pages: 76-84
- DOI
  10.1016/j.abb.2014.12.012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-26893008, KAKENHI-PLANNED-26111002
[Journal Article] Retinoic acid receptor-α up-regulates proopiomelanocortin gene expression in AtT20 corticotroph cells2014
- Author(s)
  Uruno, A.; Saito-Hakoda, A.; Yokoyama, A.; Kogure, N.; Matsuda, K.; Parvin, R.; Shimizu, K.; Sato, I.; Kudo, M.; Yoshikawa, T.; Kagechika, H.; Iwasaki, Y.; Ito, S.; Sugawara, A.
- Journal Title
  
  Endocr J
  
  Volume: 61 Issue: 11 Pages: 1105-1114
- DOI
  10.1507/endocrj.EJ14-0115
- NAID
  130004677954
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-26460383
[Journal Article] ARB affects nicotine-induced gene expression profile in human coronary artery endothelial cells.2014
- Author(s)
  Kudo M, Matsuda K, Sugawara K, Iki Y, Kogure N, Saito-Ito T, Shimizu K, Sato I, Yoshikawa T, Uruno A, Yokoyama A, Saito-Hakoda A, Ito S, Sugawara A.
- Journal Title
  
  World Journal of Hypertension.
  
  Volume: 4(1) Issue: 1 Pages: 7-14
- DOI
  10.5494/wjh.v4.i1.7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658091, KAKENHI-PROJECT-24790306
[Journal Article] Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice.2014
- Author(s)
  Hirotsu Y, Higashi C, Fukutomi T, Katsuoka F, Tsujita T, Yagishita Y, Matsuyama Y, Motohashi H, Uruno A, and Yamamoto M.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 19 Issue: 8 Pages: 650-665
- DOI
  10.1111/gtc.12165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-25750357, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26893008
[Journal Article] Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymes2014
- Author(s)
  Tsujita T, Peirce V, Baird L, Matsuyama Y, Takaku M, Walsh SV, Griffin JL, Uruno A, Yamamoto M, and Hayes JD.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 34 Issue: 20 Pages: 3800-3816
- DOI
  10.1128/mcb.00110-14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-25750357, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460383
[Journal Article] Nrf2 induces fibroblast growth factor 21 in diabetic mice2014
- Author(s)
  Furusawa Y, Uruno A, Yagishita Y, Higashi C, and Yamamoto M.
- Journal Title
  
  Genes Cells
  
  Volume: 19 Issue: 12 Pages: 864-878
- DOI
  10.1111/gtc.12186
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-26893008
[Journal Article] Angiotensin II receptor blockers differentially affect CYP11B2 expression in human adrenal H295R cells.2014
- Author(s)
  Matsuda K, Uruno A, Kogure N, Sugawara K, Shimada H, Nezu M, Saito-Ito T, Iki Y, Kudo M, Shimizu K, Sato I, Yoshikawa T, Satoh F, Ito R, Yokoyama A, Rainey WE, Saito-Hakoda A, Ito S, Sugawara A.
- Journal Title
  
  Mol Cell Endocrinol.
  
  Volume: 383(1-2) Issue: 1-2 Pages: 60-68
- DOI
  10.1016/j.mce.2013.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658091, KAKENHI-PROJECT-24790306, KAKENHI-PROJECT-25461381, KAKENHI-PROJECT-26460383
[Journal Article] Isocitrate dehydrogenase mutation is frequently observed in giant cell tumor of bone2014
- Author(s)
  Kato-Kaneko M, Liu X, Oki H, Ogasawara S, Nakamura T, Saidoh N, Tsujimoto Y, Matsuyama Y, Uruno A, Sugawara M, Tsuchiya T, Yamakawa M, Yamamoto M, Takagi M, Kato Y.
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Issue: 6 Pages: 744-748
- DOI
  10.1111/cas.12413
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-25460451, KAKENHI-PROJECT-26460383
[Journal Article] Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice2014
- Author(s)
  Yagishita Y, Fukutomi T, Sugawara A, Kawamura H, Takahashi T, Pi J, Uruno A, and Yamamoto M.
- Journal Title
  
  Diabetes
  
  Volume: 63 Issue: 2 Pages: 605-618
- DOI
  10.2337/db13-0909
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790306, KAKENHI-PROJECT-23390458
[Journal Article] The Keap1-Nrf2 system prevents onset of diabetes mellitus2013
- Author(s)
  Uruno A, Furusawa Y, Yagishita Y, Fukutomi T, Muramatsu H, Negishi T, Sugawara A, Kensler TW, Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 33 Issue: 15 Pages: 2996-3010
- DOI
  10.1128/mcb.00225-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790306
[Journal Article] Keap1-Nrf2システムによる惇8細胞保護作用2013
- Author(s)
  5. 宇留野晃
- Journal Title
  
  日本応用酵素協会誌
  
  Volume: 48 Pages: 68-69
- URL
  http://www.mt-pharma.co.jp/jfae/
- Data Source
  KAKENHI-PROJECT-24790306
[Journal Article] 糖尿病発症における酸化ストレスの役割2012
- Author(s)
  6. 宇留野晃
- Journal Title
  
  日本応用酵素協会誌
  
  Volume: 47 Pages: 72-72
- URL
  http://www.mt-pharma.co.jp/jfae/
- Data Source
  KAKENHI-PROJECT-24790306
[Journal Article] Effects of PPAR γ agonists against vascular and renal dysfunction2012
- Author(s)
  Sugawara A, Uruno A, Matsuda K, Funato T, Saito-Hakoda A, Kudo M, Ito S
- Journal Title
  
  Curr Mol Pharmacol
  
  Volume: (未定)(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma2012
- Author(s)
  Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, Sugawara S, Watanabe M, Sakurada A, Endo C, Uruno A, Sasano H, Nakagawa T, Satoh K, Tanaka N, Kubo H, Motohashi H, Yamamoto M
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 4 Pages: 760-766
- DOI
  10.1111/j.1349-7006.2012.02216.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22390163, KAKENHI-PROJECT-23592521, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-24591184, KAKENHI-PROJECT-24592613, KAKENHI-PROJECT-24790306, KAKENHI-PLANNED-23116002
[Journal Article] Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma2012
- Author(s)
  Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, Sugawara S, Watanabe M, Sakurada A, Endo C, Uruno A, Sasano H, Nakagawa T, Satoh K, Tanaka N, Kubo H, Motohashi H, Yamamoto M
- Journal Title
  
  Cancer Sci
  
  Volume: 103(4) Pages: 760-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] Effects of PPARγ agonists against vascular and renal dysfunction2012
- Author(s)
  Sugawara A, Uruno A, Matsuda K, Saito-Ito T, Funato T, Saito-Hakoda A, Kudo M, Ito S.
- Journal Title
  
  Curr Mol Pharmacol
  
  Volume: 5 Issue: 2 Pages: 248-254
- DOI
  10.2174/1874467211205020248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591006, KAKENHI-PROJECT-24790306
[Journal Article] 核内受容体および肝細胞増殖因子による血管応答機構の解明2011
- Author(s)
  宇留野晃
- Journal Title
  
  東北医学雑誌
  
  Volume: 123 Pages: 203-206
- NAID
  120006873306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] All-trans retinoic acid and a novel synthetic retinoid tamibarotene(Am80)differentially regulate CD38 expression in human leukemia HL-60 cells : possible involvement of protein kinase C-S2011
- Author(s)
  Uruno A, Noguchi N, Matsuda K, Nata K, Yoshikawa T, Chikamatsu Y, Kagechika H, Harigae H, Ito S, OkamotoH, Sugawara A.
- Journal Title
  
  J Leukoc Biol.
  
  Volume: In press(未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] 膵β細胞におけるKeap1-Nrf2システムの役割2011
- Author(s)
  宇留野晃
- Journal Title
  
  日本応用酵素協会誌
  
  Volume: 46 Pages: 90-90
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] The Keapl-Nrf2 system as an in vivo sensor for electrophiles.2011
- Author(s)
  Uruno A, Motohashi H.
- Journal Title
  
  Ncitric Oxide.
  
  Volume: In press(未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] The Keap1-Nrf2 system as an in vivo sensor for electrophiles2011
- Author(s)
  Uruno A, Motohashi H
- Journal Title
  
  Nitric Oxide
  
  Volume: 25(2) Pages: 153-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL-60 cells: possible involvement of protein kinase C-{delta}2011
- Author(s)
  Uruno A, Noguchi N, Matsuda K, Nata K, Yoshikawa T, Chikamatsu Y, Kagechika H, Harigae H, Ito S, Okamoto H, Sugawara A.
- Journal Title
  
  J Leukoc Biol
  
  Volume: 90 Issue: 2 Pages: 235-247
- DOI
  10.1189/jlb.0109025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591006, KAKENHI-PROJECT-22890014
[Journal Article] Peroxisome proliferator-activated receptor-γ suppresses CYPIIB2 expression and aldosterone production.2011
- Author(s)
  Uruno A, Matsuda K, Noguchi N, Yoshikawa T, Kudo M, Satoh F, Rainey WE, Hui XG, Akahira JI, Nakamura Y, Sasano H, Okamoto H, Ito S, Sugawara A.
- Journal Title
  
  J Mol Endocrinol.
  
  Volume: 46 Pages: 37-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] 核内受容体および肝細胞増殖因子による血管応答機構の解明膵β細胞におけるKeap1-Nrf2システムの役割2011
- Author(s)
  宇留野晃
- Journal Title
  
  日本応用酵素協会誌
  
  Volume: 46 Pages: 90-90
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] Peroxisome proliferator-activated receptor-γ suppresses CYP11B2 expression and aldosterone production2011
- Author(s)
  Uruno A, Matsuda K, Noguchi N, Yoshikawa T, Kudo M, Satoh F, Rainey WE, Hui XG, Akahira JI, Nakamura Y, Sasano H, Okamoto H, Ito S, Sugawara A
- Journal Title
  
  J Mol Endocrinol
  
  Volume: 46(1) Pages: 37-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80)differentially regulate CD38 expression in human leukemia HL-60 cells : possible involvement of protein kinase C-δ2011
- Author(s)
  Uruno A, Noguchi N, Matsuda K, Nata K, Yoshikawa T, Chikamatsu Y, Kagechika H, Harigae H, Ito S, Okamoto H, Sugawara A
- Journal Title
  
  J Leukoc Biol
  
  Volume: 90(2) Pages: 235-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] ストレスと生体反応. Nrf2-Keap1システムによるストレス応答制御2010
- Author(s)
  宇留野晃、森口尚、山本雅之
- Journal Title
  
  Diabetes Frontier
  
  Volume: 21 Pages: 412-417
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] Up-regulation of REG I α accelerates tumor progression in Pancreatic cancer with diabetes.2010
- Author(s)
  Zhou L, Zhang R, Wang L, Shen S, Okamoto H, SugawaraA, Xia L, Wang X, Noguchi N, Yoshikawa T, Uruno A, Yao W, Yuan Y.
- Journal Title
  
  Int J Cancer.
  
  Volume: 127 Pages: 1795-1803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] PPARγによるCYP11B2およびアルドステロン分泌調節機構の検討2010
- Author(s)
  宇留野晃
- Journal Title
  
  日本応用酵素協会誌
  
  Volume: 45 Pages: 101-102
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] チアゾリジン誘導体はPPARγおよびCa^<2+>/カルモジュリン依存性キナーゼ(CaMK)を介して副腎皮質癌H295R細胞におけるアルドステロン分泌を抑制する2010
- Author(s)
  宇留野晃、松田謙、野口直哉、吉川雄朗、工藤正孝、佐藤文俊、伊藤貞嘉、岡本宏、菅原明
- Journal Title
  
  ACTH related peptides
  
  Volume: 20 Pages: 36-37
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] レチノイド受容体によるPOMC転写調節機構2010
- Author(s)
  宇留野晃、菅原明、松田謙、岩崎泰正、斉藤明子、工藤正孝、伊藤貞嘉
- Journal Title
  
  ACTH related peptides
  
  Volume: 20 Pages: 25-26
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] PPARγと生活習慣病2010
- Author(s)
  菅原明、宇留野晃、松田謙、工藤正孝、伊藤貞嘉
- Journal Title
  
  ホルモンと臨床
  
  Volume: 58 Pages: 143-148
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] Up-regulation of REG Iα accelerates tumor progression in pancreatic cancer with diabetes2010
- Author(s)
  Zhou L, Zhang R, Wang L, Shen S, Okamoto H, Sugawara A, Xia L, Wang X, Noguchi N, Yoshikawa T, Uruno A, Yao W, Yuan Y
- Journal Title
  
  Int J Cancer
  
  Volume: 127(8) Pages: 1795-803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890014
[Journal Article] PPARy2 induction by sterol depletion in preadipocytes2007
- Author(s)
  Kudo M, Sugawara A, Uruno A, Ito S.
- Journal Title
  
  Shinryo to Shinyaku 44
  
  Pages: 367-369
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] Effects of PPARv and EAR on atherosclerosis2007
- Author(s)
  Sugawara A, Uruno A, Kudo M.
- Journal Title
  
  Nakatomi Foundation 18^<th> H19
  
  Pages: 63-65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] Transcriptional regulation of rat gene by retinoblastoma interacting zinc finger protein2007
- Author(s)
  Uruno A, Sugawara A, Kudo M, Ito S.
- Journal Title
  
  Shinryo to SMayaiu 44
  
  Pages: 361-366
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] Retinoblastoma interacting zinc finger proteinによるラットヘムオキシゲナーゼ_1遺伝子の転写調節2007
- Author(s)
  宇留野晃、菅原明、工藤正孝、伊藤貞嘉
- Journal Title
  
  診療と新薬 44
  
  Pages: 361-366
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor : possible involvement of paracrine effects of endogenous vascular endothelial growth factor signaling.2007
- Author(s)
  Saito A, Sugawara A, Uruno A, et al.
- Journal Title
  
  Endocrinology 148(3)
  
  Pages: 1412-1423
- Data Source
  KAKENHI-PROJECT-17790545
[Journal Article] All-trans retinoic acid induces in vitro angiogenesis viaretinoic acid receptor : possible involvement of endogenous vascular endothelial growth factor signaling.2007
- Author(s)
  Saito A, Sugawara A, Uruno A, Kudo M, Kagechika H, Sato Y, Owada Y, Kondo H, Sato M, Kurabayashi M, Imaizumi M, Tsuchiya S, Ito S
- Journal Title
  
  Endocrinology 148
  
  Pages: 1412-1423
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] ホルモン核内受容体-PPARγおよびレチノイン酸受容体-の活性化を用いた新しい抗動脈硬化療法の開発2007
- Author(s)
  菅原明、宇留野晃、工藤正孝
- Journal Title
  
  財団法人中冨健康科学振興財団第18回研究助成業績集平成19年版
  
  Pages: 63-65
- NAID
  10027299733
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor: possible involvement of endogenous vascular endothelial growth factor signaling.2007
- Author(s)
  Saito A, Sugawara A, Uruno A, Kudo M, Kagechika H, Sato Y, Owada Y, Kondo H, Sato M, Kurabayashi M, Imaizumi M, Tsuchiya S, Ito S
- Journal Title
  
  Endocrinology 148
  
  Pages: 1412-1423
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] Retinoblastoma interacting zinc finger proteinによるラットヘムオキシゲナーゼ-1遺伝子の転写調節2007
- Author(s)
  宇留野晃、菅原明、工藤正孝、伊藤貞嘉
- Journal Title
  
  診療と新薬 44
  
  Pages: 361-366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor: possible involvement of endogenous vascular endothelial growth factor signaling2007
- Author(s)
  Saito A, Sugawara A, Uruno A, Kudo M, Kagechika H, Sato Y, Owada Y, Kondo H, Sato M, Kurabayashi M, Imaizumi M, Tsuchiya S, Ito S.
- Journal Title
  
  Endocrinology 148
  
  Pages: 1412-1423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] 核内受容体PPAR-γ2の脂肪前駆細胞におけるコレステロール欠乏誘導性の発現亢進2007
- Author(s)
  工藤正孝、菅原明、宇留野晃、伊藤貞嘉
- Journal Title
  
  診療と新薬 44
  
  Pages: 367-369
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] 全トランス型レチノイン酸および合成レチノイドAm80の血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた検討-。2006
- Author(s)
  菅原明, 斉藤明子, 宇留野晃, 今泉益栄, 工藤正孝, 影近弘之, 本郷道夫, 伊藤貞嘉
- Journal Title
  
  血圧 13
  
  Pages: 250-252
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] 抗動脈硬化作用を有する心血管作動物質としてのレチノイン酸 : その血管内皮機能をよび血管新生に及ぼす影響の検討。2006
- Author(s)
  菅原明, 宇留野晃, 斉藤明子, 工藤正孝, 伊藤貞嘉
- Journal Title
  
  脈管学 46
  
  Pages: 365-368
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] 全トランス型レチノイン酸および合成レチノイドAm80の血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた検討-。2006
- Author(s)
  菅原明、斉藤明子、宇留野晃、今泉益栄、工藤正孝、影近弘之、本郷道夫、伊藤貞嘉
- Journal Title
  
  血圧 13
  
  Pages: 250-252
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] 抗動脈硬化作用を有する心血管作動物質としてのレチノイン酸:その血管内皮機能および血管新生に及ぼす影響の検討。2006
- Author(s)
  菅原明、宇留野晃、斉藤明子、工藤正孝、伊藤貞嘉
- Journal Title
  
  脈管学 46
  
  Pages: 365-368
- NAID
  10018260717
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] グレリンの血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた解析-。2006
- Author(s)
  菅原明、斉藤明子、宇留野晃、工藤正孝、伊藤貞嘉
- Journal Title
  
  厚生労働科学研究費補助金(難治性疾患克服研究事業)間脳下垂体機能障害調査研究班総括・分担研究報告書平成17年度
  
  Pages: 88-95
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] Effects of ATRA on endothelial function and angiogenesis2006
- Author(s)
  Sugawara A, Uruno A, Saito A, Kudo M, Ito S.
- Journal Title
  
  Myakkanngaku 46
  
  Pages: 365-368
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] Effects of ATRA and synthetic retinoid Am80 on endothelial gene expression-DNA microarray analyses2006
- Author(s)
  Sugawara A, Saito A, Uruno A, Imaizumi M, Kudo M, Kagechika H, Hongo M, Ito S.
- Journal Title
  
  Ketsuatsu 13
  
  Pages: 250-252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] Effects of ghrelin on endothelial gene expression-DNA microarray analyses2006
- Author(s)
  Sugawara A, Saito A, Uruno A, Kudo M, Ito S.
- Journal Title
  
  Granta''in-Aidfrom the Ministry of Health, Labor, and Welfare of Japan Report H17
  
  Pages: 88-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Journal Article] Upregulation of nitric oxide production in vascular endothelial cells by all-trans retinoic acid through the phosphoinositide 3-kinase/Akt pathway.2005
- Author(s)
  Uruno A, et al.
- Journal Title
  
  Circulation 112(5)
  
  Pages: 724-736
- Data Source
  KAKENHI-PROJECT-17790545
[Patent] 生体組織上の還元型グルタチオン分布を測定する方法及び診断用データの取得方法2019
- Inventor(s)
  山本雅之、宇留野晃、三枝大輔、齋藤律水
- Industrial Property Rights Holder
  山本雅之、宇留野晃、三枝大輔、齋藤律水
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-122085
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16KK0195
[Patent] 生体組織上の還元型グルタチオン分布を測定する方法及び診断用データの取得方法2019
- Inventor(s)
  山本雅之、宇留野晃、三枝大輔、齋藤律水
- Industrial Property Rights Holder
  山本雅之、宇留野晃、三枝大輔、齋藤律水
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-122085
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K01837
[Patent] Nrf2活性化のバイオマーカー2013
- Inventor(s)
  山本雅之、宇留野晃、古津祐樹
- Industrial Property Rights Holder
  国立大学法人東北大学持田製薬株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-112877
- Filing Date
  2013-05-29
- Data Source
  KAKENHI-PROJECT-24790306
[Patent] Nrf2活性化のバイオマーカー2013
- Inventor(s)
  山本雅之、宇留野晃、古澤祐樹
- Industrial Property Rights Holder
  東北大学、持田製薬株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-112877
- Filing Date
  2013-05-29
- Data Source
  KAKENHI-PROJECT-24790306
[Patent] 糖尿病の予防または治療剤2012
- Inventor(s)
  山本雅之、宇留野晃、古澤祐樹
- Industrial Property Rights Holder
  国立大学法人東北大学, 持田製薬株式会社
- Industrial Property Number
  2012-072990
- Filing Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] アルツハイマー病における脳内グルタチオンおよびアミノ酸代謝の検討2021
- Author(s)
  古川奈々花, 宇留野晃, 齋藤律水, 三枝大輔, 斉藤貴志, 西道隆臣, 本橋ほづみ, 山本雅之
- Organizer
  日本生化学会東北支部第87回例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07352
[Presentation] The multiple functions of Nrf2 in diabetes mellitus and obesity2019
- Author(s)
  Uruno A
- Organizer
  The Environmental Response V
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KK0195
[Presentation] The multiple functions of Nrf2 in diabetes mellitus and obesity2019
- Author(s)
  Uruno A
- Organizer
  The Environmental Response V
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01837
[Presentation] Development and Evaluation of Ultrasound-facilitated Drug Delivery Device2018
- Author(s)
  Kenji Inoue, Aya Sato, Ryuta Saito, Jia Wenting, Saori Okuno, Yuji Ohashi3, Kei Kamada, Akira Yoshikawa, Teiji Tominaga
- Organizer
  2018 ISAF-FMA-AMF-AMEC-PFM Joint Conference (IFAAP 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04299
[Presentation] イソチアゾール骨格を有する新規Nrf2活性化剤の創製2016
- Author(s)
  斉藤文彦、神野智之、中原基、水野貴志、竹内勝俊、荒井ゆかり、千代田幸治、川本雅毅、前田能崇、東知佳、林真貴子、津田直人、河路淳子、村井武彦、内田一也、神谷昌嗣、那波弘康、中尾一成、古迫正司、宇留野晃、山本雅之
- Organizer
  第34回メディシナルケミストリーシンポジウム
- Place of Presentation
  つくば（つくば国際会議場）
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] 糖尿病におけるKeap1-Nrf2系の役割2016
- Author(s)
  宇留野晃、柳下陽子、山本雅之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台（仙台国際センター）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] Nrf2によるグリコーゲン分枝鎖酵素遺伝子発現制御機構の解明2016
- Author(s)
  相川享、宇留野晃、柳下陽子、山本雅之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台（仙台国際センター）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] A novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice.2016
- Author(s)
  Higashi C, Hayashi M, Tsuda N, Kawaji A, Nakao K, Satoh F, Nakamura M, Furusako S, Saito R, Suzuki T, Uruno A, Yamamoto M.
- Organizer
  The 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis
- Place of Presentation
  ロンドン（イギリス）
- Year and Date
  2016-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] Identification and Evaluation of Isothiazole-Based Novel Nrf2 inducers2016
- Author(s)
  Saitoh F, Kamino T, Nakahara M, Mizuno T, Takeuchi K, Arai Y, Chiyoda K, Kawamoto M, Maeda Y, Higashi C, Hayashi M, Tsuda N, Kawaji A, Murai T, Uchida K, Kamiya M, Naba H, Nakao K, Furusako S, Uruno A, Yamamoto M.
- Organizer
  The 35th National Medicinal Chemistry Symposium
- Place of Presentation
  シカゴ（アメリカ合衆国）
- Year and Date
  2016-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] Keap1-Nrf2システムによるTrsp欠失マウス膵β細胞および視床下部の酸化ストレス防御機構2015
- Author(s)
  柳下陽子、福富俊明、宇留野晃、山本雅之
- Organizer
  第38回分子生物学会/第88回日本生化学会大会合同大会(BMB2015)
- Place of Presentation
  神戸 (神戸ポートアイランド)
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] Nrf2 regulates glucose metabolism-related genes.2015
- Author(s)
  Yoko Yagishita, Akira Uruno, Fumiki Katsuoka, Thomas Kensler, Masayuki Yamamoto
- Organizer
  27th Annual UPCI Scientific Retreat
- Place of Presentation
  Pittsburgh, USA
- Year and Date
  2015-06-18
- Data Source
  KAKENHI-PROJECT-26893008
[Presentation] レチノイドX受容体アゴニストPA024が副腎CYP11B2発現・アルドステロン分泌に及ぼす影響の検討2015
- Author(s)
  鈴木大、箱田明子、清水恭子、パービンレハナ、宇留野晃、青木聡、佐藤郁子、島田洋樹、小暮直敬、藤原幾磨、伊藤貞嘉、影近弘之、横山敦、菅原明
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  東京 (ホテルニューオータニ)
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] 種々のレチノイドX受容体アゴニストは, AtT20細胞の増殖・アポトーシス・Pomc発現・ACTH分泌に異なる影響を及ぼす2015
- Author(s)
  箱田明子、宇留野晃、清水恭子、パービンレハナ、横山敦、吉川雄朗、工藤正孝、影近弘之、岩崎泰正、伊藤貞嘉、菅原明
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  東京 (ホテルニューオータニ)
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] Pomc遺伝子のグルココルチコイドによるネガティブ・レギュレーションにおけるNeuroD1の関与2015
- Author(s)
  パービンレハナ、箱田明子、清水恭子、宇留野晃、鈴木大、青木聡、島田洋樹、小暮直敬、工藤正孝、岩崎泰正、伊藤貞嘉、横山敦、菅原明
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  東京 (ホテルニューオータニ)
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] 骨格筋におけるNrf2のグリコーゲン代謝制御機構2015
- Author(s)
  宇留野晃、柳下陽子、山本雅之
- Organizer
  第３８回日本分子生物学会年会　第８８回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26893008
[Presentation] Nrf2 regulates glucose metabolism-related genes.2015
- Author(s)
  Yagishita Y, Uruno A, Katsuoka F, Funayama R, Nakayama K, Yamamoto M.
- Organizer
  The Keap1/Nrf2 Pathway in Health and Disease
- Place of Presentation
  Cambridge (Robinson College)
- Year and Date
  2015-01-07
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] Nrf2 regulates glucose metabolism-related genes2015
- Author(s)
  Yagishita Y, Uruno A, Katsuoka F, Funayama R, Nakayama K, Kensler TW, Yamamoto M.
- Organizer
  27th Annyal UPCI Scientific Retreat
- Place of Presentation
  Pittsburgh (アメリカ合衆国)
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] Nrf2 regulates glycogen metabolism in skeletal muscle.2015
- Author(s)
  Uruno A, Yagishita Y, Yamamoto M.
- Organizer
  The Keap1/Nrf2 Pathway in Health and Disease
- Place of Presentation
  Cambridge (Robinson College)
- Year and Date
  2015-01-07
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] 骨格筋におけるNrf2のグリコーゲン代謝制御機構2015
- Author(s)
  宇留野晃、柳下陽子、山本雅之
- Organizer
  第88回日本生化学会大会合同大会(BMB2015)
- Place of Presentation
  神戸 (神戸ポートアイランド)
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] Keap1-Nrf2システムによるTrsp欠失マウス膵β細胞および視床下部の酸化ストレス防御機構2015
- Author(s)
  柳下陽子、福富俊明、宇留野晃、山本雅之
- Organizer
  第３８回日本分子生物学会年会　第８８回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26893008
[Presentation] Nrf2による糖尿病の発症抑制作用2014
- Author(s)
  宇留野晃、古澤祐樹、柳下陽子、山本雅之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] Nrf2 protects pancreaticβ- cells from oxidative and nitrosative stress in diabetic model mice2014
- Author(s)
  Yagishita Y, Fukutomi T, Sugawara A, Pi J, Uruno A, Yamamoto M
- Organizer
  The Environmental Response IV (Oral presentation of selected poster session)
- Place of Presentation
  sendai
- Year and Date
  2014-03-01
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] The Keap1-Nrf2 system prevents onset of diabetes mellitus2014
- Author(s)
  Uruno A, Furusawa Y, Yagishita Y, Fukutomi T, Muramatsu H, Negishi T, Sugawara A, Kensler T. W., Yamamoto M
- Organizer
  The Environmental Response IV
- Place of Presentation
  sendai
- Year and Date
  2014-02-28
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] Nrf2による酸化ストレス糖尿病モデルマウスの膵β細胞保護2014
- Author(s)
  柳下陽子、宇留野晃、福富俊明、菅原明、山本雅之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice.2014
- Author(s)
  Yagishita Y, Fukutomi T, Sugawara A, Pi J, Uruno A, Yamamoto M.
- Organizer
  The Environmental Response IV
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] Keap1-Nrf2システムは糖尿病発症を抑制する2014
- Author(s)
  宇留野晃、古澤祐樹、柳下陽子、福富俊明、山本雅之
- Organizer
  第80回日本生化学会東北支部例会
- Place of Presentation
  秋田（アキタパークホテル）
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PROJECT-26460383
[Presentation] The Keap1-Nrf2 system prevents onset of diabetes mellitus.2014
- Author(s)
  Uruno A, Furusawa Y, Yagishita Y, Fukutomi T, Muramatsu H, Negishi T, Sugawara A, Kensler TW, Yamamoto M.
- Organizer
  The Environmental Response IV
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] 種々のレチノイドX受容体(RXR)アゴニストは、AtT20細胞の増殖・アポトーシス・POMC発現・ACTH分泌に異なる影響を及ぼす2013
- Author(s)
  4. 箱田明子、宇留野晃、清水恭子、伊藤貴子、萱岐裕子、吉川雄朗、松田謙、工藤正孝、影近弘之、岩崎泰正、伊藤貞嘉、菅原明
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台
- Year and Date
  2013-04-27
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] 高血糖刺激は副腎アルドステロン合成酵素の発現をT型Caチャネルの発現増加を介して誘導す2013
- Author(s)
  7. 小暮直敬、伊藤貴子、菅原香織、松田謙、萱岐裕子、佐藤郁子、皆川敬治、勝木将人、清水恭子、吉川雄朗、工藤正孝、宇留野晃、箱田明子、伊藤貞嘉、菅原明
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台
- Year and Date
  2013-04-25
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] Keap1-Nrf2システムによる膵β細胞保護作用2013
- Author(s)
  柳下陽子、宇留野晃、福富俊明、菅原明、川村仁、高橋哲、山本雅之
- Organizer
  第77回日本生化学会東北支部会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] 高血糖刺激はヒト副腎H295R細胞における118-水酸化酵素遺伝子(CYP11B1)発現を誘導する2013
- Author(s)
  6.菅原香織、伊藤貴子、小暮直敬、皆川敬治、萱岐裕子、勝木将人、宇留野晃、佐藤郁子、田中智博、太田期、木谷優介、塚田晃也、大熊崇生、角田亮、清水恭子、工藤正孝、松田謙、箱田明子、伊藤貞嘉、菅原明
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台
- Year and Date
  2013-04-25
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] ニコチンのヒト冠動脈血管内皮細胞の遺伝子発現に及ぼす影響ならびにそれに対するARBの効果2013
- Author(s)
  5. 萱岐裕子、工藤正孝、伊藤貴子、菅原香織、松田謙、小暮直敬、皆川敬治、勝木将人、佐藤郁子、宇留野晃、清水恭子、吉川雄朗、箱田明子、伊藤貞嘉、菅原明
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台
- Year and Date
  2013-04-26
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] Keap1-Nrf2システムによる惇8細胞保護作用2013
- Author(s)
  3. 柳下陽子、宇留野晃、福富俊明、菅原明、川村仁、高橋哲、山本雅之
- Organizer
  日本生化学会東北支部第79回例
- Place of Presentation
  仙台
- Year and Date
  2013-05-11
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] 高血糖刺激によるアルドステロン合成酵素(CYP11B2)の発現増強効果2012
- Author(s)
  16. 松田謙、伊藤貴子、宇留野晃、中村美輝、高橋朗、吉川雄朗、清水恭子、箱田明子、工藤正孝、佐藤文俊、伊藤貞嘉、菅原明
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] 各アンジオテンシンII受容体桔抗薬(ARB)はアルドステロン合成酵素(CYP11B2)発現に異なる影響を及ぼす(第三報)2012
- Author(s)
  13. 松田謙、宇留野晃、伊藤貴子、清水恭子、吉川雄朗、箱田明子、工藤正孝、佐藤文俊、伊藤貞嘉、菅原明
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2012-04-21
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] 全トランスレチノイン酸(ATRA)と合成レチノイドAm80は、血球・血管内皮間接着ならびに血球表面CD38発現に異なる影響を及ぼす2012
- Author(s)
  12. 宇留野晃、松田謙、吉川雄朗、箱田明子、伊藤貞嘉、岡本宏、菅原明
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2012-04-21
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] Telmisartan stimulates aldosterone synthase gene (CYP11B2) expression via the CaMK - mediated induction of NURR12012
- Author(s)
  Matsuda K, Uruno A, Saito-Ito T, Shimizu K, Kudo M, Satoh F, Yoshikawa T, Saito-Hakoda A, Ito S, Sugawara A
- Organizer
  The Endocrine Society 94th Annual Meeting
- Place of Presentation
  Houston, USA
- Year and Date
  2012-06-23
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] High glucose stimulates aldosterone synthase gene (CYP11B2) expression in human adrenal H295R cells2012
- Author(s)
  Saito, Ito T, Matsuda K, Uruno A, Shimizu K, Nakamura M, Takahashi R, Yoshikawa T, Kudo M, Saito, Hakoda A, Ito S, Sugawara
- Organizer
  The Endocrine Society 94th Annual Meeting
- Place of Presentation
  Houston, USA
- Year and Date
  2012-06-23
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] レチノイン酸受容体(RAR)αはNeuroD1・Tpitを介してPOMC遺伝子発現を充進する2012
- Author(s)
  11. 宇留野晃、箱田明子、松田謙、清水恭子、伊藤貴子、工藤正孝、岩崎泰正、伊藤貞嘉、菅原明
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2012-04-21
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] Retinoid X receptor agonists differentially affect proliferation, apoptosis, and ACTH secretion/POMC gene expression in AtT20 corticotroph cells2012
- Author(s)
  Saito-Hakoda A, Uruno A, Shimizu K, Kudo M, Saito-Ito T, Yoshikawa T, Matsuda K, Fujiwara I, Kagechika H, Iwasaki Y, Ito S, Sugawara A
- Organizer
  The Endocrine Society 94th Annual Meeting
- Place of Presentation
  Houston, USA
- Year and Date
  2012-06-23
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] GLP-1受容体アゴニストの冠動脈血管内皮細胞の遺伝子発現に及ぼす影響の検討2012
- Author(s)
  14. 工藤正孝、松田謙、箱田明子、伊藤貴子、清水恭子、佐藤文俊、宇留野晃、伊藤貞嘉、菅原明
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] アルドステロン合成酵素および118-水酸化酵素転写解析系として使用可能な新規安定株の作製2012
- Author(s)
  15. 松田謙、宇留野晃、伊藤貴子、清水恭子、工藤正孝、箱田明子、吉川雄朗、佐藤文俊、伊藤貞嘉、菅原明
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-24790306
[Presentation] Differential effects among ARBs on aldosterone synthase (CYP11B2) gene expression in human adrenal H295R cells2011
- Author(s)
  Matsuda K, Uruno A, Kudo M, Satoh F, Ito S, Sugawara A
- Organizer
  The Endocrine Society 93rd Annual Meeting
- Place of Presentation
  ボストン、アメリカ合衆国
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] Effects of Retinoid X Receptor on ACTH Secretion and POMC Gene Expression in AtT20 Corticotroph Cells2011
- Author(s)
  Uruno A, Matsuda K, Kudo M, Iwasaki Y, Ito S, Sugawara A
- Organizer
  The Endocrine Society 93rd Annual Meeting
- Place of Presentation
  Boston
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] Effects of Retinoid X Receptor on ACTH Secretion and POMC Gene Expression in AtT20 Corticotroph Cells2011
- Author(s)
  Uruno A, Matsuda K, Kudo M, Iwasaki Y, Ito S, Sugawara A
- Organizer
  The Endocrine Society 93rd Annual Meeting
- Place of Presentation
  ボストン、アメリカ合衆国
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] 各アンジオテンシンII受容体拮抗薬(ARB)はアルドステロン合成酵素(CYP11B2)発現に異なる影響を及ぼす2011
- Author(s)
  松田謙、宇留野晃、工藤正孝、佐藤文俊、伊藤貞嘉、菅原明
- Organizer
  第84回日本内分泌学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] 膵β細胞におけるKeap1-Nrf2システムの役割2011
- Author(s)
  宇留野晃、柳下陽子、菅原明、山本雅之
- Organizer
  第77回日本生化学会東北支部会例会
- Place of Presentation
  仙台
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] 基本的血液検査データを用いたパターン認識手法に基づくクッシング症候群の早期診断支援システムの開発2011
- Author(s)
  工藤正孝、佐藤文俊、青木空眞、森本玲、岩倉芳倫、小野美澄、松田謙、村上治、宇留野晃、菅原明、佐藤憲一、伊藤貞嘉
- Organizer
  第84回日本内分泌学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] Differential effects among ARBs on aldosterone synthase (CYP11B2) gene expression in human adrenal H295R cells2011
- Author(s)
  Kudo M, Satoh F, Morimoto R, Iwakura Y, Ono Y, Murakami O, Matsuda K, Sugawara A, Uruno A, Takase K, Ito S
- Organizer
  35th Meeting of the International Aldosterone Conference
- Place of Presentation
  ボストン、アメリカ合衆国
- Year and Date
  2011-06-22
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] Relationship between Silent Brain Infarction and Primary Aldosteronism2011
- Author(s)
  Matsuda K, Uruno A, Kudo M, Satoh F, Ito S, Sugawara A
- Organizer
  35th Meeting of the International Aldosterone Conference
- Place of Presentation
  ボストン、アメリカ合衆国
- Year and Date
  2011-06-22
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] Differential effects among ARBs on aldosterone synthase (CYP11B2)gene expression in human adrenal H295R cells2011
- Author(s)
  Matsuda K, Uruno A, Kudo M, Satoh F, Ito S, Sugawara A
- Organizer
  The Endocrine Society 93rd Annual Meeting
- Place of Presentation
  Boston
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] Role of heparan sulfate in glucose-induced insulin secretion in MIN6 cells2010
- Author(s)
  Yoshikawa T, Takayanagi S, Noguchi N, Uruno A, Okamoto H, Sugawara A, Yanai K
- Organizer
  American Diabetes Association 70th Scientific Sessions
- Place of Presentation
  Orlando
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] Role of heparan sulfate in glucose-induced insulin secretion in MIN6 cells.2010
- Author(s)
  Yoshikawa T, Takayanagi S, Noguchi N, Uruno A, Okamoto H, Sugawara A, Yanai K.
- Organizer
  American Diabetes Association 70th Scientific Sessions.
- Place of Presentation
  Orlando USA
- Year and Date
  2010-06-23
- Data Source
  KAKENHI-PROJECT-22890014
[Presentation] Effects of ATRA and Am80 on angiogenesis2007
- Author(s)
  Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tuchiya S, Ito S
- Organizer
  80th Japan Endocrine Society Meeting
- Place of Presentation
  Tokyo
- Year and Date
  2007-06-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Functional significance of PPARy and RAR in cardiovascular disorders2007
- Author(s)
  Sugawara A, Uruno A, Saito A, Yang CW, Kudo M, Ito S
- Organizer
  80th Japan Endocrine Society Meeting
- Place of Presentation
  Tokyo
- Year and Date
  2007-06-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of ghrelin on endothelial gene expression2007
- Author(s)
  Kudo M, Sugawara A, Uruno A, Saito A, Ito S
- Organizer
  11th Meeting of the Society of Cardiovascular Endocrinology and Metabolism
- Place of Presentation
  Tokyo
- Year and Date
  2007-11-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] p38 mitogen-activated protein kinase is involved in up-regulation of angiogenesis in vitro by HMG-CoA reductase inhibitor fluvastatin2007
- Author(s)
  Uruno A, Sugawara A, Saito A, Kudo M, Ito S
- Organizer
  13th World Congress on Heart Disease
- Place of Presentation
  Vancouver
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] FK506-binding protein 12.6ノックアウトマウスにおけるブドウ糖刺激インスリン分泌の低下2007
- Author(s)
  吉川雄朗、野口直哉、池田崇之、高橋巌、Nausheen J. Shervani、宇留野晃、山内晶世、那谷耕司、高澤伸、岡本宏、菅原明
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] FK506 disruption impairs glucose-induced insulin secretion2007
- Author(s)
  Yoshikawa T, Noguchi N, Ikeda T, Takahashi I, Shervani NJ, Uruno A, Yamauchi A, Nata K, Takasawa S, Okamoto H, Sugawara A
- Organizer
  80th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] フルバスタチンによる管腔形成促進作用はp38 MAPキナーゼに依存する2007
- Author(s)
  宇留野晃、菅原明、斉藤明子、工藤正孝、伊藤貞嘉
- Organizer
  第80回日本内分泌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2007-06-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] 核内レセプターを標的とした生活習慣病治療:PPRA_Yとレチノイン酸受容体2007
- Author(s)
  菅原明、宇留野晃、斉藤明子、Yang Chul Woo、工藤正孝、伊藤貞嘉
- Organizer
  第80回日本内分泌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2007-06-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] 糖転移酵素EXTL3の膵β細胞特異的欠損マウスにおけるβ細胞増殖能の低下と耐糖能異常2007
- Author(s)
  高橋巌、那谷耕司、野口直哉、池田崇之、吉川雄朗、山内晶世、Nausheen J. Shervani、杉原一司、浅野雅秀、宇留野晃、海野倫明、高澤伸、岡本宏、菅原明
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Mechanisms of ATRA-indiced angiogenesis: involvement of VEGF2007
- Author(s)
  Saito A, Sugawara A, Uruno A, Kudo M, Kagechika H, Sato Y, Imaizumi M, Tsuchiya S, Ito S
- Organizer
  18th Meeting of Japanese Society for Retinoid Research
- Place of Presentation
  Tokyo
- Year and Date
  2007-11-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] p38 mitogen-activated protein kinase is involved in up-regulation of angiogenesis in vitro by HMG-CoA reductase inhibitor fluvastatin.2007
- Author(s)
  Uruno A, Sugawara A, Saito A, Kudo M, Ito S
- Organizer
  13th World Congress on Heart Disease
- Place of Presentation
  Vancouver
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] グレリンの血管内皮細胞における遺伝子発現に及ぼす影響2007
- Author(s)
  工藤正孝、菅原明、宇留野晃、斉藤明子、伊藤貞嘉
- Organizer
  第11回日本心血管内分泌代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] レチノイン酸とAm80による血管新生促進作用の検討2007
- Author(s)
  斉藤明子、菅原明、宇留野晃、工藤正孝、今泉益栄、土屋滋、伊藤貞嘉
- Organizer
  第80回日本内分泌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2007-06-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Reduced β-cell proliferation and impaired glucose tolerance in pancreatic β-cell specific Extl3 knockout mice2007
- Author(s)
  Takahashi I, Nata K, Noguchi N, Ikeda T, YoshikawaT, Yamauchi A, Shervani NJ, Sugihara K, Asano M, Uruno A, Unno M, Takasawa S, Okamoto H, Sugawara A
- Organizer
  80th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] 全トランス型レチノイン酸による血管新生促進機構の解明-レチノイン酸受容体及びVEGFシグナルの関与-2007
- Author(s)
  斉藤明子、菅原明、宇留野晃、工藤正孝、影近弘之、佐藤靖史、今泉益栄、土屋滋、伊藤貞嘉
- Organizer
  日本レチノイド研究会第18回学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] 核内レセプターを標的とした生活習慣病治療:PPRAγとレチノイン酸受容体2007
- Author(s)
  菅原明、宇留野晃、斉藤明子、Yang Chul Woo、工藤正孝、伊藤貞嘉
- Organizer
  第80回日本内分泌学会学術総会(シンポジウム)
- Place of Presentation
  東京
- Year and Date
  2007-06-16
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Fluvastatin induces angiogenesis through p38 MAPK2007
- Author(s)
  Uruno A, Sugawara A, Saito A, Kudo M, Ito S
- Organizer
  80th Japan Endocrine Society Meeting
- Place of Presentation
  Tokyo
- Year and Date
  2007-06-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of hepatocyte growth factor and fluvastatin co-administration on in vitro angiogenesis and endothelial cell proliferation.2006
- Author(s)
  Uruno A, Sugawara A, Saito A, Kudo M, Ito S.
- Organizer
  The 21st Scientific Meeting of the International Society of Hypertnesion.
- Place of Presentation
  福岡
- Year and Date
  2006-10-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] プロスタサイクリンの血管新生および血管内皮細胞における遺伝子発現に及ぼす影響の検討。2006
- Author(s)
  菅原明、工藤正孝、斉藤明子、宇留野晃、本郷道夫、伊藤貞嘉
- Organizer
  第6回日本NO学会学術集会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Differential effects of angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker on gene expression in vascular endothelial cells revealed by DNA microarray analyses2006
- Author(s)
  Sugawara A, Kudo M, Saito A, Hongo M, Uruno A, Ito S
- Organizer
  The 21st Scientific Meeting of the International Society of Hypertnesion
- Place of Presentation
  Fukuoka
- Year and Date
  2006-10-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] グレリンの血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた検討-。2006
- Author(s)
  菅原明、斉藤明子、工藤正孝、宇留野晃、本郷道夫、伊藤貞嘉
- Organizer
  第79回日本内分泌学会学術総会
- Place of Presentation
  神戸
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Biphasic effects of fluvastatin on hepatocyte growth factor-induced in vitro angiogenesis and endothelial cell proliferation2006
- Author(s)
  Uruno A, Sugawara A, Saito A, Kudo M, Ito S
- Organizer
  International Symposium The Kidney and Hypertension
- Place of Presentation
  Sendai
- Year and Date
  2006-10-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of ATRA on angiogenesis2006
- Author(s)
  Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tsuchiya S, Ito S
- Organizer
  10th Meeting of the Society of Cardiovascular Endocrinology and Metabolism
- Place of Presentation
  Fukui
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of ghrelin on endothelial gene expression-DNA microarray analyses-2006
- Author(s)
  Sugawara A, Saito A, Kudo M, Uruno A, Hongo M, Ito S
- Organizer
  79th Japan Endocrine Society Meeting
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Biphasic effects of fluvastatin on hepatocyte growth factor-induced in vitro angiogenesis and endothelial cell proliferation.2006
- Author(s)
  Uruno A, Sugawara A, Saito A, Kudo M, Ito S.
- Organizer
  International Symposium The Kidney and Hypertension.
- Place of Presentation
  仙台
- Year and Date
  2006-10-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of prostacyclin on endothelial gene expression-DNA microarray analyses-2006
- Author(s)
  Kudo M, Sugawara A, Saito A, Uruno A, Ito S
- Organizer
  10th Meeting of the Society of Cardiovascular Endocrinology and Metabolism
- Place of Presentation
  Fukui
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] レチノイン酸の血管新生に対する効果。2006
- Author(s)
  斉藤明子、菅原明、工藤正孝、宇留野晃、今泉益栄、伊藤貞嘉
- Organizer
  第12回日本内分泌学会東北地方会
- Place of Presentation
  仙台
- Year and Date
  2006-04-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] 肝細胞増殖因子とスタチン製剤の併用による血管新生および細胞増殖能の検討。2006
- Author(s)
  宇留野晃、菅原明、斉藤明子、工藤正孝、伊藤貞嘉
- Organizer
  第49回日本腎臓学会学術総会
- Place of Presentation
  東京
- Year and Date
  2006-06-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of prostacyclin on eNOS phosphprylation2006
- Author(s)
  Kudo M, Sugawara A, Uruno A, Ito S
- Organizer
  6th Annual Scientific Meeting of the NO Society of Japan
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of all-trans retinoic acid on in vitro angiogenesis2006
- Author(s)
  Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tsuchiya S, Ito S
- Organizer
  The 21st Scientific Meeting of the International Society of Hypertnesion
- Place of Presentation
  Fukuoka
- Year and Date
  2006-10-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] 肝細胞増殖因子とスタチン製剤の併用による血管新生および細胞増殖能の検討。2006
- Author(s)
  宇留野晃、菅原明、斉藤明子、工藤正孝、伊藤貞嘉
- Organizer
  第10回日本心血管内分泌代謝学会
- Place of Presentation
  福井
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] 血管内皮細胞におけるプロスタサイクリンによるeNOSリン酸化機構の解明。2006
- Author(s)
  工藤正孝、菅原明、宇留野晃、伊藤貞嘉
- Organizer
  第6回日本NO学会学術集会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker demonstra differential gene expression profiles in vascular endothelial cells2006
- Author(s)
  Sugawara A, Kudo M, Saito A, Hongo M, Uruno A, Ito S
- Organizer
  International Symposium The Kidney and Hypertension
- Place of Presentation
  Sendai
- Year and Date
  2006-10-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] レチノイン酸の血管新生に対する効果。2006
- Author(s)
  斉藤明子、菅原明、宇留野晃、工藤正孝、今泉益栄、飯沼一宇、伊藤貞嘉
- Organizer
  第79回日本内分泌学会学術総会
- Place of Presentation
  神戸
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Differential effects of thiazolidinedione, prostacyclin, and statin on gene expression profiles in vascular endothelial cells2006
- Author(s)
  Kudo M, Sugawara A, Saito A, Uruno A, Ito S
- Organizer
  International Symposium The Kidney and Hypertension
- Place of Presentation
  Sendai
- Year and Date
  2006-10-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of HGF and statin on angiogenesis and cell growth2006
- Author(s)
  Uruno A, Sugawara A, Saito A, Kudo M, Ito S
- Organizer
  10th Meeting of the Society of Cardiovascular Endocrinology and Metabolism
- Place of Presentation
  Fukui
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] All-trans retinoic acid induces in vitro angiogenesis possibly via vascular endothelial growth factor signaling2006
- Author(s)
  Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tsuchiya S, Ito S
- Organizer
  International Symposium The Kidney and Hypertension
- Place of Presentation
  Sendai
- Year and Date
  2006-10-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of ACEi and ARB on endothelial gene expression-DNA microarray analyses-2006
- Author(s)
  Sugawara A, Kudo M, Saito A, Uruno A, Ito S
- Organizer
  10th Meeting of the Society of Cardiovascular Endocrinology and Metabolism
- Place of Presentation
  Fukui
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Differential effects of thiazolidinedione, prostacyclin, and statin on gene expression profiles in vascular endothelial cells.2006
- Author(s)
  Kudo M, Sugawara A, Saito A, Uruno A, Ito S.
- Organizer
  International Symposium The Kidney and Hypertension.
- Place of Presentation
  仙台
- Year and Date
  2006-10-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] 血管内皮細胞の遺伝子発現に及ぼすグレリンの影響-マイクロアレイを用いた検討-。2006
- Author(s)
  菅原明、斉藤明子、工藤正孝、宇留野晃、伊藤貞嘉
- Organizer
  第33回日本神経内分泌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2006-10-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] ACE阻害薬およびアンジオテンシンII受容体拮抗薬の血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた検討-。2006
- Author(s)
  菅原明、工藤正孝、斉藤明子、宇留野晃、伊藤貞嘉
- Organizer
  第10回日本心血管内分泌代謝学会
- Place of Presentation
  福井
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] 肝細胞増殖因子とスタチン系製剤の併用による血管新生作用の検討。2006
- Author(s)
  宇留野晃、菅原明、斉藤明子、工藤正孝、伊藤貞嘉
- Organizer
  第79回日本内分泌学会学術総会
- Place of Presentation
  神戸
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of HGF and statin on angiogenesis and cell growth2006
- Author(s)
  Uruno A, Sugawara A, Saito A, Kudo M, Ito S.
- Organizer
  49th Annual Meeting of the Japanese Society of Nephrology
- Place of Presentation
  Tokyo
- Year and Date
  2006-06-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of ATRA on angiogenesis2006
- Author(s)
  Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Iinuma K, Ito S
- Organizer
  79th Japan Endocrine Society Meeting.
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] レチノイン酸による血管新生促進作用の検討。2006
- Author(s)
  斉藤明子、菅原明、宇留野晃、工藤正孝、今泉益栄、土屋滋、伊藤貞嘉
- Organizer
  第10回日本心血管内分泌代謝学会
- Place of Presentation
  福井
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of pioglitazone, belaprost, and fluvastatin on gene expression in vascular endothelial cells revealed by DNA microarray analyses2006
- Author(s)
  Kudo M, Sugawara A, Saito A, Uruno A, Ito S
- Organizer
  The 21st Scientifi Meeting of the International Society of Hypertnesion
- Place of Presentation
  Fukuoka
- Year and Date
  2006-10-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] プロスタサイクリンの血管内皮細胞における遺伝子発現に及ぼす影響-マイクロアレイを用いた検討-。2006
- Author(s)
  工藤正孝、菅原明、斉藤明子、宇留野晃、伊藤貞嘉
- Organizer
  第10回日本心血管内分泌代謝学会
- Place of Presentation
  福井
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker demonstrate differential gene expression profiles in vascular endothelial cells.2006
- Author(s)
  Sugawara A, Kudo M, Saito A, Hongo M, Uruno A, Ito S.
- Organizer
  International Symposium The Kidney and Hypertension.
- Place of Presentation
  仙台
- Year and Date
  2006-10-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of HGF and statin on angiogenesis2006
- Author(s)
  Uruno A, Sugawara A, Saito A, Kudo M, Ito S
- Organizer
  79th Japan Endocrine Society Meeting
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of ghrelin on endothelial gene expression-DNA microarray analyses-2006
- Author(s)
  Sugawara A, Saito A, Kudo M, Uruno A, Ito S
- Organizer
  33th Japan Neuroendocrine Society Meeting
- Place of Presentation
  Yokohama
- Year and Date
  2006-10-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of all-trans retinoic acid on in vitro angiogenesis.2006
- Author(s)
  Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tsuchiya S, Ito S.
- Organizer
  The 21st Scientific Meeting of the International Society of Hypertnesion.
- Place of Presentation
  福岡
- Year and Date
  2006-10-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of pioglitazone, belaprost, and fluvastatin on gene expression in vascular endothelial cells revealed by DNA microarray analyses.2006
- Author(s)
  Kudo M, Sugawara A, Saito A, Uruno A, Ito S.
- Organizer
  The 21st Scientific Meeting of the International Society of Hypertnesion.
- Place of Presentation
  福岡
- Year and Date
  2006-10-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of prostacyclin on angiogenesis and endothelial gene expression2006
- Author(s)
  Sugawara A, Kudo M, Saito A, Uruno A, Hongo M, Ito S
- Organizer
  6th Annual Scientific Meeting of the NO Society of Japan
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Differential effects of angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker on gene expression in vascular endothelial cells revealed by DNA microarray analyses.2006
- Author(s)
  Sugawara A, Kudo M, Saito A, Hongo M, Uruno A, Ito S.
- Organizer
  The 21st Scientific Meeting of the International Society of Hypertnesion.
- Place of Presentation
  福岡
- Year and Date
  2006-10-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of hepatocyte growth factor and fluvastatin co-administration on in vitro angiogenesis and endothelial cell proliferation2006
- Author(s)
  Uruno A, Sugawara A, Saito A, Kudo M, Ito S
- Organizer
  The 21st Scientific Meeting of the International Society of Hypertnesion
- Place of Presentation
  Fukuoka
- Year and Date
  2006-10-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Effects of ATRA on angiogenesis2006
- Author(s)
  Saito A, Sugawara A, Kudo M, Uruno A, Imaizumi M, Ito S
- Organizer
  12th Tohoku Endocrine Meeting
- Place of Presentation
  Sendai
- Year and Date
  2006-04-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] All-trans retinoic acid induces in vitro angiogenesis possibly via vascular endothelial growth factor signaling.2006
- Author(s)
  Saito A, Sugawara A, Uruno A, Kudo M, Imaizumi M, Tsuchiya S, Ito S.
- Organizer
  International Symposium The Kidney and Hypertension.
- Place of Presentation
  仙台
- Year and Date
  2006-10-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591015
[Presentation] Nrf2による糖尿病の発症抑制作用
- Author(s)
  宇留野晃、古澤祐樹、柳下陽子、山本雅之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府、京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26893008
[Presentation] Nrf2 regulates glycogen metabolism in skeletal muscle
- Author(s)
  Akira Uruno, Yoko Yagishita, Masayuki Yamamoto
- Organizer
  The Keap1/Nrf2 Pathway in Health and Disease
- Place of Presentation
  Cambridge, UK
- Year and Date
  2015-01-06 – 2015-01-08
- Data Source
  KAKENHI-PROJECT-26893008
[Presentation] Nrf2 regulates glucose metabolism-related genes
- Author(s)
  Yoko Yagishita, Akira Uruno, Fumiki Katsuoka, Ryo Funayama, Keiko Nakayama, Masayuki Yamamoto
- Organizer
  The Keap1/Nrf2 Pathway in Health and Disease
- Place of Presentation
  Cambridge, UK
- Year and Date
  2015-01-06 – 2015-01-08
- Data Source
  KAKENHI-PROJECT-26893008
[Presentation] Nrf2による酸化ストレス糖尿病モデルマウスの膵β細胞保護
- Author(s)
  柳下陽子、宇留野晃、福富俊明、菅原明、山本雅之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府、京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26893008
[]
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[]

1. YAMAMOTO Masayuki (50166823)

# of Collaborated Projects: 4 results

# of Collaborated Products: 40 results
2. YAGISHITA YOKO (50733838)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
3. KATSUOKA Fumiki (30447255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SUZUKI Norio (20447254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. SUGAWARA Akira (90270834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 79 results
6. ITO Sadayoshi (40271613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 69 results
7. SATO Yasufumi (50178779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. KAGECHIKA Hiroyuki (20177348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
9. SATO Akira (20250764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. Furukawa Yoshihiro (00544107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Saito Ryuta (10400243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 中村智樹 (20260721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 三枝大輔 (90545237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 冨永悌二 (00217548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAGANUMA Eriko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. DATE Fumiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Saito Ritsumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SUZUKI Takafumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
19. TAGUCHI Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. YOKOYAMA Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
21. HAKODA Akiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. SHIMA hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. NORO erika

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. KUDO Masataka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 小柴生造

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 富永悌二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 野口直哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 布施昇男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 本橋ほづみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
30. 中村智洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uruno Akira 宇留野 晃

URUNO Akira 宇留野 晃

宇留野 晃 ウルノ アキラ

Research Projects

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Nrf2 and Neuroinflammation in Alzheimer's diseasePrincipal Investigator

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Glutathione regulations in Alzheimer's diseasePrincipal Investigator

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Roles of oxidative stress in metabolic regulations(Fostering Joint International Research)Principal Investigator

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Role of Nrf2 in Alzheimer's disease with diabetes mellitusPrincipal Investigator

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Investigation on imaging of distribution of organic molecules in meteorites

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Basic Research for Development of Chemical Surgery

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The role of Nrf2 in oxidative stress-mediated insulin resistancePrincipal Investigator

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The role of Nrf2 in pancreatic beta-cells; a study of new pancreatic beta-cell specific Nrf2 activation model mice

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Roles of stress-responsive transcription factors in health and disease

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The role of Keap1-Nrf2 system in obesity-induced pancreatic beta-cell dysfunctionsPrincipal Investigator

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The role of Keap1-Nrf2 system in oxidative stress response of pancreatic β-cellsPrincipal Investigator

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レチノイン酸による血管内皮におけるPI3キナーゼ調節機構の解明Principal Investigator

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EFFECTS OF ALL-TRANS RETINOIC ACID AND RETINOIDS ON ANGIOGENESIS

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Uruno Akira 宇留野晃

URUNO Akira 宇留野晃

宇留野晃ウルノアキラ