YASUDA Hiroyasu 安田浩康

Researcher Number	90396482
Other IDs
Affiliation (based on the past Project Information) *help	2013: 東北大学, 大学院医学系研究科, 非常勤講師 2011 – 2013: 東北大学, 医学(系)研究科(研究院), 非常勤講師 2012: 東北大学, 大学院・医学系研究科, 非常勤講師 2008 – 2011: Tohoku University, 未来医工学治療開発センター, 准教授 2008: 東北大学, 未来医工学治療開発センター・臨床応用部門, 准教授 2007: Kyoto University, 医学研究科, 講師 2005 – 2006: 東北大学, 病院, 医員
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine Except Principal Investigator General surgery / Medical sociology
Keywords	Principal Investigator 一酸化窒素 / 腫瘍循環 / ニトログリセリン / 低酸素誘導因子 / 非小細胞肺癌 / 臨床試験 / 抗癌剤感受性増強効果 / FPGS / RFC-1 / ペメトレキセド … More / がん細胞 / 腫瘍縮小効果 / ゲムシタビン / アムルビシン / 化学療法感受性 / 無作為化比較試験 / 腫瘍組織内低酸素状態 / 腫瘍直接浸潤 / 抗癌剤感受性 / 一酸化窒素供与剤 / P糖蛋白質 / 腫瘍微小循環 / 腫瘍内低酸素 / 多施設無作為化臨床試験 / 化学療法 / 生存シグナル / 血管内皮成長因子 / P糖蛋白 / 多施設第II相proof of concept臨床試験 / 腫瘍内微小循環 / 低酸素誘導性抗がん薬耐性化機序 / P-glycoprotein / VEGF / Hypoxia-inducible factor-1 / 抗癌剤耐性 / 腫瘍内微小血管密度 / 固形癌内部における低酸素状態 … More Except Principal Investigator 上乗せ効果 / 上乗せ効 / 化学療法 / 乳がん / 一酸化窒素 / 低酸素癌細胞 / HK II / HIF-1α / 一酸化窒素供与剤 / 乳腺外科学 / TAPS / CTCAE / RECIST / ガイドライン / 臨床腫瘍学 / がん診療 / 医学教育学 Less

Translational Research for cobinational chemotherapy with tumor microcirculation promotional agent in patients with advanced non-small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  YASUDA Hiroyasu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
The study that nitroglycerin treatment may increase response to chemotherapy via inhibitions of hypoxia-inducible factor-1 pathway in patients with breast cancer.
- Principal Investigator
  
  AMARI Masakazu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tohoku University
Educational system of oncology
- Principal Investigator
  
  YANAGIHARA Kazuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical sociology
- Research Institution
  Kyoto University
The basic and clinical research regarding development of combinationalchemotherapy with nitric oxide donating drugs for non-small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  YASUDA Hiroyasu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
  Kyoto University
一酸化窒素供与剤併用による新規肺癌治療法開発の研究Principal Investigator
- Principal Investigator
  
  安田浩康
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

[Book] Nitric Oxide and Cancer : Prognosis and Therapy2010
- Author(s)
  Yasuda H, Bonavida B
- Publisher
  Springer(印刷中)
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Nitric oxide enhances pemetrexed cytotoxicity via NO-cGMP signaling in lung adenocarcinoma cells in vitro and in vivo2013
- Author(s)
  Nagai H, Yasuda H, Hatachi Y, Xue D, Sasaki T, Yamaya M, Sakamori Y, Togashi Y, Masago K, Ito I, Kim YH, Mio T, Mishima M.
- Journal Title
  
  Int J Oncology
  
  Volume: 41 Pages: 3271-3278
- DOI
  10.3892/ijo.2012.1461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591133, KAKENHI-PROJECT-23591146
[Journal Article] Use of glucose solution for the alleviation of gemcitabine-induced vascular pain: a double blind randomized crossover study.2013
- Author(s)
  Nagai H, Kitano T, Nishimura T, Yasuda H, Nakata K, Takashima S, Kanai M, Matsumoto S, Mori Y, Kakudo Y, Sato H, Yamaguchi T, Kameno K, Kim YH, Mishima M, Yanagihara K.
- Journal Title
  
  Support Care Cancer
  
  Volume: 21 Issue: 12 Pages: 3271-3278
- DOI
  10.1007/s00520-013-1901-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591133
[Journal Article] Nitric oxide enhances pemetrexed cytotoxicity via NO-cGMP signaling in lung adenocarcinoma cells in vitro and in vivo2012
- Author(s)
  Nagai N, Yasuda H, Hatachi Y, et al.
- Journal Title
  
  Int J Oncology
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591133
[Journal Article] A new strategy with proton pump inhibitors for the prevention of acute exacerbations in COPD2011
- Author(s)
  Sasaki T, Nakayama K, Yasuda H, et al.
- Journal Title
  
  Ther Adv Respir Dis
  
  Volume: 5 Pages: 91-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591133
[Journal Article] Therapeutic applications of nitric oxide for malignant tumor in animal models and human studies.2010
- Author(s)
  Yasuda H, Yanagihara K, Nakayama K, Mio T, Sasaki T, Asada M, Yamaya M, Fukushima M.
- Journal Title
  
  Nitric Oxide and Cancer: Prognosis and Therapy (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Clarithromycin inhibits type A seasonal influenza virus infection in human airway epithelial cells2010
- Author(s)
  Yamaya M, Shinya K, Hatachi Y, Kubo H, Asada M, Yasuda H, et al.
- Journal Title
  
  J Pharm Exp Ther 333
  
  Pages: 81-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Clarithromycin inhibits type A seasonal influenza virus infection in human airway epithelial cells.2010
- Author(s)
  Yamaya M, Shinya K, Hatachi Y, Kubo H, Asada M, Yasuda H, Nishimura H, Nagatomi R.
- Journal Title
  
  J Pharm Exp Ther 333
  
  Pages: 81-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small-cell lung cancer.2010
- Author(s)
  Yanagihara K, Yoshimura K, Niimi M, Yasuda H, et. al.
- Journal Title
  
  Cancer Chemother Pharmacol (in press)
- NAID
  120002515188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small-cell lung cancer2010
- Author(s)
  Yanagihara K, Yoshimura K, Niimi M, Yasuda H, et al.
- Journal Title
  
  Cancer Chemother Pharmacol (In press)
- NAID
  120002515188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Dual antibody plus chemotherapy in metastatic colorectal cancer.2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 339-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Nitric oxide and cancer immunity in solid tumor tissues.2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 338-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] 気道疾患2009
- Author(s)
  山谷睦雄、吉田元樹、中山勝敏、安田浩康, ら
- Journal Title
  
  The Lung Perspective 17
  
  Pages: 43-47
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Fas signal and cancer progression2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 337-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Macrolide antibiotics inhibit respiratory syncytial virus infection in human airway epithelial cells2009
- Author(s)
  Asada M, Yoshida M, Suzuki T, Yasuda H, et al.
- Journal Title
  
  Antiviral Res 83
  
  Pages: 191-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Carbocisteine inhibits oxidant-induced apoptosis in cultured human airway epithelial cells.2009
- Author(s)
  Yoshida M, Nakayama K, Yasuda H, et. al.
- Journal Title
  
  Respirology 14
  
  Pages: 1027-1034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] 喀痰調整薬のライノウイルス感染・気道炎症抑制作用と臨床効果2009
- Author(s)
  安田浩康、佐々木陽彦、中山勝敏、吉田元樹、旗智幸政、永井宏樹、Deng Xue、山谷睦雄
- Journal Title
  
  化学療法の領域 25
  
  Pages: 83-92
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Nitric oxide and cancer immunity in solid tumor tissues2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 338-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Carbocisteine inhibits oxidant-induced apoptosis in cultured human airway epithelial cells2009
- Author(s)
  吉田元樹, 中山勝敏, 安田浩康, et al.
- Journal Title
  
  Respirology 14
  
  Pages: 1027-1034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] A history of smoking is inversely correlated with the incidence of gemcitabine- induced neutropenia.2009
- Author(s)
  Kanai M, Morita S, Matsumoto S, Nishimura T, Hatano E, Yazumi S, Sasaki T, Yasuda H, et. al.
- Journal Title
  
  Ann Oncol 20
  
  Pages: 1397-1401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] A randomized, single blind study of lansoprazole for the prevention of exacerbations of chronic obstructive pulmonary disease in older patients2009
- Author(s)
  佐々木陽彦, 中山勝敏, 安田浩康, et al.
- Journal Title
  
  J Am Geriatr Soc 57
  
  Pages: 1453-1457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Macrolide antibiotics inhibit respiratory syncytial virus infection in human airway epithelial cells.2009
- Author(s)
  Asada M, Yoshida M, Suzuki T, Yasuda H, et. al.
- Journal Title
  
  Antiviral Res 83
  
  Pages: 191-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] 喀痰調整薬のライノウイルス感染・気道炎症抑制作用と臨床効果2009
- Author(s)
  安田浩康、佐々木陽彦、中山勝敏, ら
- Journal Title
  
  化学療法の領域 25
  
  Pages: 83-92
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Dual antibody plus chemotherapy in metastatic colorectal cancer2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 339-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Fas signal and cancer progression.2009
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, Yanagihara K.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 337-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] A randomized, single blind study of lansoprazole for the prevention of exacerbations of chronic obstructive pulmonary disease in older patients.2009
- Author(s)
  Sasaki T, Nakayama K, Yasuda H, et. al.
- Journal Title
  
  J Am Geriatr Soc 57
  
  Pages: 1453-1457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Submucosal gland cells in human lower airways produce MUC5AC protein.2008
- Author(s)
  Inoue D, Kubo H, Watanabe M, Sasaki T, Yasuda H, et. al.
- Journal Title
  
  Respirology 13
  
  Pages: 285-287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Clincal outcome of combination therapy of gemcitabine with S-1 for advanced pancreatic cancer.2008
- Author(s)
  Yamauchi J, Kanai M, Matsumoto S, Nishimura T, Yazumi S, Kamei K, Kawaguchi Y, Yasuda H, et. al.
- Journal Title
  
  Pancreas 36
  
  Pages: 327-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Prolonged neutropenia after dose-dense chemotherapy with pegfilgrastim.2008
- Author(s)
  Ishiguro H, Kitano T, Yoshibayashi H, Toi M, Ueno T, Yasuda H, et. al.
- Journal Title
  
  Ann Oncol 19
  
  Pages: 1019-1019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Solid tumor physiology and hypoxia-induced chemo/radio-resistance: Novel strategy for cancer therapy: Nitric oxide donor as a therapeutic enhancer.2008
- Author(s)
  Yasuda H.
- Journal Title
  
  Nitric Oxide: Biology and Chemistry 19
  
  Pages: 205-216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Erythromycin attenuates MUC5AC synthesis and secretion in cultured human tracheal cells infected with RV14.2008
- Author(s)
  Inoue D, Kubo H, Sasaki T, Yasuda H, et. al.
- Journal Title
  
  Respirology 13
  
  Pages: 215-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Reduced tumor growth in a mouse model of schizophrenia, lacking the dopamine transporter.2008
- Author(s)
  Asada M, Ebihara S, Numachi Y, Okazaki T, Yamanda S, Ikeda K, Yasuda H, Sora I, Arai H
- Journal Title
  
  Int J Cancer 123
  
  Pages: 511-518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Solid tumor physiology and hypoxiainduced chemo / radioresistance : Novel strategy for cancer therapy : Nitric oxide donor as a therapeutic enhancer2008
- Author(s)
  Yasuda H
- Journal Title
  
  Nitric Oxide : Biology and Chemistry 19
  
  Pages: 205-216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] 進行非小細胞肺癌における抗癌剤とニトログリセリン併用療法の個別化医療への展望2007
- Author(s)
  安田浩康、中山勝敏、山谷睦雄, ら
- Journal Title
  
  分子呼吸器病特集肺癌:個別化医療への最先端研究 11
  
  Pages: 45-52
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Treatment and prevention of COPD exacerbation.2007
- Author(s)
  Yamaya M, Yasuda H, Yoshida M, et al.
- Journal Title
  
  Nippon Rinsho 65
  
  Pages: 734-739
- NAID
  40015395576
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] 糖尿病合併肺炎の診療上の注意点2007
- Author(s)
  安田浩康、中山勝敏、山谷睦雄
- Journal Title
  
  診断と治療 95
  
  Pages: 81-84
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Partial response by nitroglycerin plus amrubicin regimen in patients with refractory and recurrent advanced non-small cell lung cancer who had received at least third-line chemotherapy: Case report.2007
- Author(s)
  Yasuda H, Nakayama K, Sasaki T, et al.
- Journal Title
  
  Cancer Therapy 5
  
  Pages: 451-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Prevalence and incidence of anemia in Japanese cancer patients receiving outpatient chemotherapy.2007
- Author(s)
  Kitano T, Tada H, Nishimura T, Teramukai S, Kanai M, Nishimura T, Misawa A, Yoshikawa K, Yasuda H, et. al.
- Journal Title
  
  Int J Hematol 86
  
  Pages: 37-41
- NAID
  10018515509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Hochu-ekki-to inhibits rhinovirus infection in human tracheal epithelial cells.2007
- Author(s)
  Yamaya M, Sasaki T, Yasuda H, et al.
- Journal Title
  
  Brit J Pharmacol 150
  
  Pages: 702-710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Acid and swallowing reflex.2007
- Author(s)
  Ebihara T, Ebihara S, Ohrui T, Yasuda H, et al.
- Journal Title
  
  Geriatr Gerontol Int 7
  
  Pages: 94-95
- NAID
  10019489828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Tumor hypoxia imaging with[F-18]fluoronitro- imidazole in non-small-cell lung cancer.2007
- Author(s)
  Yasuda H, Kaneta T, Takai Y, et al.
- Journal Title
  
  J Am Geriatr Soc 55
  
  Pages: 1142-1144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Partial response by nitroglycerin plus amrubicin regimen in patients with refractory and recurrent advanced non-small cell lung cancer who had received at least third-line chemotherapy2007
- Author(s)
  Yasuda H, et. al.
- Journal Title
  
  Cancer Therapy 5
  
  Pages: 451-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Tumor hypoxia imaging with [F-18] fluoronitroimidazole in non-small-cell lung cancer.2007
- Author(s)
  Yasuda H, et. al.
- Journal Title
  
  J Am Geriatr Soc 55
  
  Pages: 1142-1144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Initial evaluation of dynamic human imaging using 18F-FRP170 as a new PET tracer for imaging hypoxia.2007
- Author(s)
  Kaneta T, Takai Y, Iwata R, Hakamatsuka T, Yasuda H, et al.
- Journal Title
  
  Ann Nucl Med 21
  
  Pages: 101-107
- NAID
  10018874948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689018
[Journal Article] Association of susceptibility to the development of pneumonia in older Japanese population with the haem oxygenase-l gene promoter polymorphism,2006
- Author(s)
  Hiroyasu Yasuda, et al.
- Journal Title
  
  Journal of Medical Genetics (印刷中)
- Data Source
  KAKENHI-PROJECT-17790524
[Journal Article] Arterial Carboxyhemoglobin Concentrations as a Predictor for Chemosensitivity in Elderly Patients with Advanced Lung Cancer.2006
- Author(s)
  Hiroyasu Yasuda, et al.
- Journal Title
  
  Journal of American Geriatrics Society 54
  
  Pages: 373-375
- Data Source
  KAKENHI-PROJECT-17790524
[Journal Article] Nitroglycerin treatment may increase response to docetaxel and carboplatin in patients with lung adenocarcinoma.2006
- Author(s)
  Hiroyasu Yasuda, et al.
- Journal Title
  
  Clinical Cancer Research 12
  
  Pages: 6748-6757
- Data Source
  KAKENHI-PROJECT-17790524
[Journal Article] Carbocisteine inhibits rhinovirus infection in human tracheal epithelial cells.2006
- Author(s)
  Hiroyasu Yasuda, et al.
- Journal Title
  
  European Respiratory Journal 28
  
  Pages: 51-58
- Data Source
  KAKENHI-PROJECT-17790524
[Journal Article] Association of susceptibility to the development of pneumonia in older Japanese population with the haem oxygenase-1 gene promoter polymorphism.2006
- Author(s)
  Hiroyasu Yasuda, et al.
- Journal Title
  
  Journal of Medical Genetics 43
- Data Source
  KAKENHI-PROJECT-17790524
[Journal Article] Carbocisteine inhibits rhinovirus infection in human tracheal epithelial cells.2006
- Author(s)
  Hiroyasu Yasuda, et al.
- Journal Title
  
  European Respiratory Society (印刷中)
- Data Source
  KAKENHI-PROJECT-17790524
[Journal Article] Randomized Phase II Trial Comparing Nitroglycerin Plus Vinorelbine and Cisplatin With Vinorelbine and Cisplatin alone in Previously Untreated Stage IIIB/IV Non-small Cell Lung Cancer.2006
- Author(s)
  Hiroyasu Yasuda, et al.
- Journal Title
  
  Journal of Clinical Oncology 24
  
  Pages: 688-694
- Data Source
  KAKENHI-PROJECT-17790524
[Journal Article] Increased arterial carboxyhemoglobin concentrations in patients with chronic obstructive pulmonary disease.2005
- Author(s)
  Hiroyasu Yasuda, et al.
- Journal Title
  
  American Journal of Respiratory Critical Care Medicine 171
  
  Pages: 1246-1251
- Data Source
  KAKENHI-PROJECT-17790524
[Journal Article] Partial response by nitroglycerin plus amrubicin regimen in patients with refractory and recurrent advanced non-small cell lung cancer who had received at least third-line chemotherapy : Case report.
- Author(s)
  Hiroyasu Yasuda, et al.
- Journal Title
  
  Cancer Therapy (印刷中)
- Data Source
  KAKENHI-PROJECT-17790524
[Journal Article] Tumor hypoxia imaging with [F-18] fluoronitroimidazole in non-small-cell lung cancer.
- Author(s)
  Hiroyasu Yasuda, et al.
- Journal Title
  
  Journal of American Geriatrics Society (印刷中)
- Data Source
  KAKENHI-PROJECT-17790524
[Patent] 肺疾患の治療に用いられる気体製剤及びそれを用いた吸入療法2010
- Inventor(s)
  安田浩康、佐々木陽彦、中山勝敏、海老原覚、山谷睦雄、福島雅典
- Industrial Property Rights Holder
  東北大学、フクダ電子
- Industrial Property Number
  2009-117078
- Filing Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-19689018
[Patent] 肺疾患の治療に用いられる気体製剤及びそれを用いた吸入療法2009
- Inventor(s)
  安田浩康、佐々木陽彦、中山勝敏、海老原覚、山谷睦雄、福島雅典
- Industrial Property Rights Holder
  東北大学、フクダ電子株式会社
- Industrial Property Number
  2009-117078
- Filing Date
  2009-05-13
- Data Source
  KAKENHI-PROJECT-19689018
[Patent] 気体製剤、及び低濃度一酸化炭素を用いた吸入療法2008
- Inventor(s)
  安田浩康
- Industrial Property Rights Holder
  安田浩康
- Industrial Property Number
  2008-205312
- Filing Date
  2008-08-08
- Data Source
  KAKENHI-PROJECT-19689018
[Patent] POTENTIATING AGENT FOR EFFECT OF ANTICANCER AGENT2005
- Inventor(s)
  Hiroyasu Yasuda
- Industrial Property Rights Holder
  Hiroyasu Yasuda
- Filing Date
  2005-06-10
- Data Source
  KAKENHI-PROJECT-17790524
[Presentation] Nitric oxide may improve pemetrexed cytotoxicity in lung adenocarcinoma cells2011
- Author(s)
  Hiroyasu Yasuda, Hiroki Nagai
- Organizer
  16th World Congress on Advances in Oncology(招待講演)
- Place of Presentation
  Rhodes island, Greece
- Data Source
  KAKENHI-PROJECT-23591133
[Presentation] 肺高血圧症合併慢性閉塞性肺疾患症例に対する低濃度一酸化炭素吸入療法の効果.2009
- Author(s)
  安田浩康
- Organizer
  第46回日本臨床生理学会総会
- Place of Presentation
  盛岡(ワークショップ)
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] PK/PD解析から見た抗がん剤の効果・副作用)固形がんに対する一酸化窒素供与剤併用化学療法.2009
- Author(s)
  安田浩康
- Organizer
  第17回クリニカルファーマシーシンポジウム医療薬学フォーラム2009
- Place of Presentation
  京都(シンポジウム4)
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Solid tumor physiology and hypoxia-induced chemo/radio-resistance: Novel strategy for cancer therapy: Nitric oxide donor as a therapeutic enhancer.2009
- Author(s)
  安田浩康
- Organizer
  第9回日本NO学会学術集会
- Place of Presentation
  静岡(シンポジウム)
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] 固形癌組織の生理学的特徴と新規治療戦略2009
- Author(s)
  安田浩康
- Organizer
  第1回信州肺癌セミナー
- Place of Presentation
  長野県松本市
- Year and Date
  2009-06-11
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Novel strategy for cancer therapy with nitroglycerin as a NO donor2009
- Author(s)
  安田浩康
- Organizer
  International Workshop on Nitric Oxide in Cancer Therapy
- Place of Presentation
  Dijon, France
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] The effects of low-dose inhaled carbon monoxide on the dyspnea in patients with chronic obstructive pulmonary disease2009
- Author(s)
  Sasaki T, Yasuda H, Nakayama K, et al.
- Organizer
  ATS 2009
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2009-04-18
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] 固形がんに対する一酸化窒素供与剤併用化学療法2009
- Author(s)
  安田浩康
- Organizer
  第17回クリニカルファーマシーシンポジウム医療薬学フォーラム2009
- Place of Presentation
  京都府京都市
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] The effects of low-dose inhaled carbon monoxide on the dyspnea in patients with chronic obstructive pulmonary disease2009
- Author(s)
  安田浩康
- Organizer
  14^<th> World Congress on Advances in Oncology and 12^<th> International Symposium on Molecular Medicine
- Place of Presentation
  Loutraki, Greece
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] P-glycoprotein (P-gp) May Be Associated with Chemoresistance to Amrubicin (AMR) in Lewis Lung Carcinoma (LLC)2009
- Author(s)
  Yasuda H, Sasaki T, Asada M, et al.
- Organizer
  ATS 2009
- Place of Presentation
  San Diego, USA
- Year and Date
  2009-05-19
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Inhibitory Effects of Nitroglycerin on Intratumor P-Glycoprotein and Phospholyrated Caveolin-1 in Lewis Lung Carcinoma Bearing Murine Model2009
- Author(s)
  Hatachi Y, Yasuda H, Nagai H, et al.
- Organizer
  ATS 2009
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2009-04-19
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Inhibitory Effects of Nitroglycerin on Intratumor P-Glycoprotein and Phospholyrated Caveolin-1 in Lewis Lung Carcinoma Bearing Murine Model.2009
- Author(s)
  Hatachi Y, Yasuda H, Nagai H, et al.
- Organizer
  ATS 2009
- Place of Presentation
  San Diego, USA
- Year and Date
  2009-05-19
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Novel strategy for cancer therapy with nitroglycerin as a NO donor.2009
- Author(s)
  Yasuda H
- Organizer
  First International Workshop on Nitric Oxide in Cancer Therapy.
- Place of Presentation
  Dijon, France
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] The effects of low-dose inhaled carbon monoxide on the dyspnea in patients with chronic obstructive pulmonary disease.2009
- Author(s)
  Yasuda H
- Organizer
  14th World Congress on Advances in Oncology and 12th International Symposium on Molecular Medicine.
- Place of Presentation
  Loutraki, Greece.
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] P-glycoprotein May Be Associated with Chemoresistance to Amrubicin in Lewis Lung Carcinoma Cells2009
- Author(s)
  Yasuda H, Sasaki T, Asada M, et al.
- Organizer
  ATS 2009
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2009-04-19
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] The effects of low-dose inhaled carbon monoxide (CO) on the dyspnea in patients with chronic obstructive pulmonary disease (COPD).2009
- Author(s)
  Sasaki T, Yasuda H, Nakayama K, et al.
- Organizer
  ATS 2009
- Place of Presentation
  San Diego, USA
- Year and Date
  2009-05-19
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Solid tumor physiology and hypoxia-induced chemo/radio-resistance : Novel strategy for cancer therapy : Nitric oxide donor as a therapeutic enhancer2009
- Author(s)
  安田浩康
- Organizer
  第9回日本NO学会学術集会
- Place of Presentation
  静岡県静岡市
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] 肺高血圧症合併慢性閉塞性肺疾患症例に対する低濃度一酸化炭素吸入療法の効果2009
- Author(s)
  安田浩康
- Organizer
  第46回日本臨床生理学会総会
- Place of Presentation
  岩手県盛岡市
- Year and Date
  2009-11-23
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] PHASE II STUDY OF COMBINATION CHEMOTHERAPY WITH S-1 PLUS DOCETAXEL FOR PREVIOUSLY TREATED PATIENTS WITH NON-SMALL-CELL LUNG CANCER IN A SECOND OR THIRD LINE REGIMEN.2008
- Author(s)
  Yanagihara K, Yasuda H, Niimi M, et al.
- Organizer
  ESMO 2008
- Place of Presentation
  Stockholm, Sweeden
- Year and Date
  2008-09-15
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Glyceryl Trinitrate may enhance chemosensitivity to cisplatin and docetaxel via inhibitions of Akt signaling pathway and HIF-1 pathway and via activation of p53 in murine syngraft solid cancer model2008
- Author(s)
  Yasuda H, et.al.
- Organizer
  13^<th>World Congress on Advances in Oncology and 11^<th>International Symposium on Molecular Medicine
- Place of Presentation
  Creta Maris Hersonissos, Crete, Greece
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Glyceryl Trinitrate may enhance chemosensitivity to cisplatin and docetaxel via inhibitions of Akt signaling pathway and HIF-1 pathway and via activation of p53 in murine syngraft solid cancer model.2008
- Author(s)
  Yasuda H
- Organizer
  13th World Congress on Advances in Oncology and 11th International Symposium on Molecular Medicine.
- Place of Presentation
  Crete, Greece
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Nitroglycerin may increase response to docetaxel and cisplatin in murine syngraft solid cancer models via reduction of HIF-1α, P-gp, and phosphorylated Akt and via increase in activated p53 in tumor tissues2008
- Author(s)
  Yasuda H, Katsutoshi Nakayama, et al.
- Organizer
  AACR 2008
- Place of Presentation
  San Diego, USA
- Year and Date
  2008-04-14
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] INHIBITORY EFFECTS OF NITROGLYCERIN ON INTRATUMOR P-GLYCOPROTEIN AND PHOSPHOLYRATED CAVEOLIN-1 IN LEWIS LUNG CARCINOMA BEARING MURINE MODEL.2008
- Author(s)
  Hatachi Y, Nagai H, Mio T, Mishima M, Yasuda H
- Organizer
  13th World Congress on Advances in Oncology and 11th International Symposium on Molecular Medicine.
- Place of Presentation
  Crete, Greece
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] 肺線癌症例におけるニトログリセリン使用による腫瘍内HIF-1 pathwayの抑制効果2007
- Author(s)
  安田浩康、中山勝敏、浅田成紀, ら
- Organizer
  第5回日本臨床腫瘍学会
- Place of Presentation
  札幌(プレナリーセッションII)
- Year and Date
  2007-08-03
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Concomitant use of nitroglycerin with anticancer agents in solid cancer.2007
- Author(s)
  Yasuda H, et. al.
- Organizer
  1st NO and Cancer International Conference
- Place of Presentation
  Paris, France
- Year and Date
  2007-11-28
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Nitroglycerin treatment may increase response to docetaxel and carboplatin regimen via inhibitions of hypoxia-inducible factor-1 pathway and p-glycoprotein in patients with lung adenocarcinoma2007
- Author(s)
  Yasuda H, Nakayama K, Watanabe M, et al.
- Organizer
  ATS 2007
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Interleukin-1beta gene polymorphisms associated with risk of lung cancwe in Japanese2007
- Author(s)
  Asada M, Yasuda H, Ebihara S, et al.
- Organizer
  ATS 2007
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Carbocisteine, a mucolytic drug, prevents apoptosis in a human airway mucoepidermoid cell line induced by oxidative stress2007
- Author(s)
  Yoshida M, Yasuda H, Nakayama K, et al.
- Organizer
  ATS 2007
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Development of a novel information technology (IT) system using the electronic medical record (EMR) in daily clinical practice2007
- Author(s)
  Matsumoto S, Nishimura T, Kanai M, Ishiguro H, Yasuda H, et al.
- Organizer
  ASCO 2007
- Place of Presentation
  Chicago, USA
- Year and Date
  2007-06-03
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Nitroglycerin treatment may increase response to docetaxel and carboplatin regimen via inhibitions of hypoxia-inducible factor-1 pathway and P-glycoprotein in patients with lung adenocarcinoma.2007
- Author(s)
  Yasuda H
- Organizer
  12th World Congress on Advances in Oncology and 10th International Symposium on Molecular Medicine.
- Place of Presentation
  Crete, Greece
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Hochu-ekki-to, a traditional Japanese herbal medicine, inhibits rhinovirus infection in human tracheal epithelial cells2007
- Author(s)
  Nakayama K, Sasaki T, Yasuda H, et al.
- Organizer
  ATS 2007
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Concomitant use of nitroglycerin with anticancer agents in solid cancer.2007
- Author(s)
  Yasuda H
- Organizer
  1st International Conference on Nitric Oxide and Cancer.
- Place of Presentation
  Paris, France
- Year and Date
  2007-11-28
- Data Source
  KAKENHI-PROJECT-19689018
[Presentation] Pleurodesis with carboplatin in elderly patients with malignant pleural effusion and lung adenocarcinoma2007
- Author(s)
  Sasaki T, Yasuda H, Nakayama K, et al.
- Organizer
  ATS 2007
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-19689018

1. YANAGIHARA Kazuhiro (70332731)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. NISHIMURA Takafumi (40378732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. FUKUSHIMA Masanori (80107820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ISHIGURO Hiroshi (20422925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KANAI Masashi (70432416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MISAWA Akiko (10378755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HIRAIDE Atsushi (20199037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. AMARI Masakazu (50400312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ISHIDA Takanori (00292318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAWAI Masaaki (80513530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OHUCHI Noriaki (90203710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 梅田みか(渡辺みか) (20292344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MATSUMOTO Shigemi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KITANO Toshiyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YASUDA Hiroyasu 安田 浩康

Research Projects

Research Products

Co-Researchers

Translational Research for cobinational chemotherapy with tumor microcirculation promotional agent in patients with advanced non-small cell lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

The study that nitroglycerin treatment may increase response to chemotherapy via inhibitions of hypoxia-inducible factor-1 pathway in patients with breast cancer.

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Educational system of oncology

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

The basic and clinical research regarding development of combinationalchemotherapy with nitric oxide donating drugs for non-small cell lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

一酸化窒素供与剤併用による新規肺癌治療法開発の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Nitric Oxide and Cancer : Prognosis and Therapy2010

Author(s)

Publisher

Data Source

[Journal Article] Nitric oxide enhances pemetrexed cytotoxicity via NO-cGMP signaling in lung adenocarcinoma cells in vitro and in vivo2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Use of glucose solution for the alleviation of gemcitabine-induced vascular pain: a double blind randomized crossover study.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nitric oxide enhances pemetrexed cytotoxicity via NO-cGMP signaling in lung adenocarcinoma cells in vitro and in vivo2012

Author(s)

Journal Title

Data Source

[Journal Article] A new strategy with proton pump inhibitors for the prevention of acute exacerbations in COPD2011

Author(s)

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Data Source

[Journal Article] Therapeutic applications of nitric oxide for malignant tumor in animal models and human studies.2010

Author(s)

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[Journal Article] Clarithromycin inhibits type A seasonal influenza virus infection in human airway epithelial cells2010

Author(s)

Journal Title

Data Source

[Journal Article] Clarithromycin inhibits type A seasonal influenza virus infection in human airway epithelial cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small-cell lung cancer.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small-cell lung cancer2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Dual antibody plus chemotherapy in metastatic colorectal cancer.2009

Author(s)

YASUDA Hiroyasu 安田浩康