NAGAOKA Masato 長岡正人

Researcher Number	90397050
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2014 – 2015: 福井大学, テニュアトラック推進本部, 助教 2014: 福井大学, 学内共同利用施設等, 助教 2007 – 2008: 東京工業大学, 大学院・生命理工学研究科, 助教 2007: 東京工業大学, 大学院・生命理工学研究科, 特別研究員 2006: 東京工業大学, 大学院生命理工学研究科, 21世紀COE研究員 2006: 東京工業大学, 大学院生命理工学研究科, 助手 2005: 東京工業大学, 大学院・生命理工学研究科, 21世紀COE研究員
Review Section/Research Field	Principal Investigator Biomedical engineering/Biomaterial science and engineering / Biomedical engineering/Biological material science Except Principal Investigator Biomedical engineering/Biological material science
Keywords	Principal Investigator 幹細胞 / 肝細胞分化 / 肝細胞 / 分化誘導 / バイオマテリアル / 接着基質 / ヒトiPS細胞 / 再生医工学 / 医用高分子 / 固定型モデルマトリックス / ES細胞 / E-カドヘリン … More Except Principal Investigator … More 肝細胞 / ES細胞 / 心筋細胞 / 神経分化 / パターニング培養 / 再生医療 / ES/iPS / Ｎ－カドヘリン / Ｅ－カドヘリン / 均一系肝細胞反応 / N-カドヘリン / E-カドヘリン / 神経細胞 / 細胞マトリックス設計 / 細胞用まな板 / 再生医工学 / ES/iPS細胞 / バイオマテリアル / 細胞認識性 / ナノキャリア / E-カドヘリン-FCキメラタンパク質 / プロテインデリバリー / 遺伝子デリバリー / 糖鎖高分子 / 制ガン剤、DDS / フィブロネクチン / GFP遺伝子 / DNAデリバリー / Si-RNAデリバリー / m / 細胞認識性バイオマテリアル / ナノキャリアー / 炭酸アパタイト / 薬物伝達システム再生医療 / 器官形成 / 肝実質細胞 / トランスジェニックマウス / 赤色蛍光 / チップ / 赤色蛍光タンパク質 / 肝機能 / iPS細胞 / EHSゲル / 内皮細胞 / 人工肝臓 / バイオチップ / 肝組織 / 肝臓 / 組織工学 / 細胞 Less

Analysis of expression profile of cell surface proteins, and establishment of specific cell adhesive materials for differentiation of human iPS cells into hepatic lineage cellsPrincipal Investigator
- Principal Investigator
  
  NAGAOKA Masato
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  University of Fukui
Regulation of functions and differentiation of ES/iPS cells by designing cell-recognizable chimera matrices
- Principal Investigator
  
  AKAIKE Toshihiro
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Foundation for Advancement of International Science
  Tokyo Institute of Technology
Regulation of Stem Cells Gene Expression using Apatite nanocarriers coated with Cell-reconizable chimeric Protein.
- Principal Investigator
  
  AKAIKE Toshihiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
Development of super functional liver model based on developmental information
- Principal Investigator
  
  TAGAWA Yoh-ichi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
新規接着用マトリックス設計によるES細胞および各種幹細胞の高効率増幅と機能解析Principal Investigator
- Principal Investigator
  
  長岡正人
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology

All 2016 2015 2013 2011 2010 2008 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] 再生医療の基礎シリーズ4「再生医療のためのバイオエンジニアリング・第5章遺伝子工学手法に基づく新しい細胞マトリックス設計と再生医療への応用」2007
- Author(s)
  長岡正人, 荻原一隆, 萩原祐子, 赤池敏宏
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-17700389
[Journal Article] Design of a vitronectin-based recombinant protein as a defined substrate for differentiation of human pluripotent stem cells into hepatocyte-like cells2015
- Author(s)
  Nagaoka M, Kobayashi M, Kawai C, Mallanna SK, Duncan SA
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 8 Pages: e0136350-e0136350
- DOI
  10.1371/journal.pone.0136350
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08343, KAKENHI-PROJECT-26870230
[Journal Article] Direct observation of cell cycle progression in living mouse embryonic stem cell on an extracellular matrix of E-cadherin2013
- Author(s)
  Jovic D., Sakaue-Sawano A., Abe T., Cho CS., Nagaoka M., Miyawaki A., Akaike T.
- Journal Title
  
  Springer Plus
  
  Volume: 2 Issue: 1
- DOI
  10.1186/2193-1801-2-585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Control of Singular Cell Cycle Synchronization of Mouse ES Cells for Hepatocyte Differentiation on E-Cadherin Substratum2011
- Author(s)
  Jovic D., Haque A, Hexing B, Nagaoka M, Akaike T.
- Journal Title
  
  J.Biotechnol.Biomaterial 1:113 doi:10.4172/2155-952X.100011(2011)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Application of Recombinant Fusion Proteins for Tissue Engineering.2010
- Author(s)
  Nagaoka M, Jiang HL, Hoshiba T., Akaike T., Cho CS.
- Journal Title
  
  Annals of Biomedical Enginering 38
  
  Pages: 683-693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] An artificial extracellular matrix created by hepatocyte growth factor fused to IgG-Fc.2010
- Author(s)
  Azuma K, Nagaoka M, Cho CS, Akaike T.
- Journal Title
  
  Biomaterials 31
  
  Pages: 802-809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Design of the artificial acellular feeder layer for the efficient propagation of mouse ES cells2008
- Author(s)
  Nagaoka M, Hagiwara Y, Takemura K, Murakami Y, Li J, Duncan SA, Akaike T
- Journal Title
  
  J Biol Chem.. 283
  
  Pages: 26468-26476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Embryonic Undifferentiated Cells Show Scattering Activity on a Surface Coated With Immobilized E-Cadherin.2008
- Author(s)
  Nagaoka M, Ise H, Harada I, Koshimizu U, Maruyama A, Akaike T.
- Journal Title
  
  J. Cell Biochem 103
  
  Pages: 296-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Design of the artificial acellular feeder layer for the efficient propagation of mouse ES cells.2008
- Author(s)
  Nagaoka M, Hagiwara Y, Takemura K, Murakami Y, Li J, Duncan SA, Akaike T.
- Journal Title
  
  J Biol Chem. 283
  
  Pages: 26468-26476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Design of Artificial Extracellular Matrices and Their Application for Regenerative Medicine.2008
- Author(s)
  Yue X., Nagaoka M., Akaike T.
- Journal Title
  
  Biomaterials in Asia
  
  Pages: 143-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Embryonic Undifferentiated Cells Show Scattering Activity on a Surface Coated With Immobilized E-Cadherin2008
- Author(s)
  M. Nagaoka, H. Ise, I. Harada, U. Koshimizu, A. Maruyama, T. Akaike
- Journal Title
  
  J. Cell Biochem. 103
  
  Pages: 296-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] 細胞接着分子の利用による細胞制御-細胞生物学/遺伝子工学/材料工学/物理学間の学際的融合による細胞認識材料設計とその再生医療への応用2007
- Author(s)
  赤池敏宏、長岡正人、E.H. Chowdhoury、原田伊知郎
- Journal Title
  
  材料の科学と工学 44(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] pH-sensing nano-crystals of carbonate apatite : effects on intracellular delivery and release of DNA for efficient expression into mammalian cells.2006
- Author(s)
  Chowdhury, E.H., Maruyama, A., Kano, A., Nagaoka, M., Kotaka, M., Hirose, S., Kunou, M., Akaike, T.
- Journal Title
  
  Gene 376 (1)
  
  Pages: 87-94
- Data Source
  KAKENHI-PROJECT-17700389
[Journal Article] Surface functionalization of inorganic nano-crystals with fibronectin and E-cadherin chimera synergistically accelerates trans-gene delivery into embryonic stem cells.2006
- Author(s)
  Kutsuzawa, K., Chowdhury, E.H., Nagaoka, M., Maruyama, K., Akiyama, Y., Akaike, T.
- Journal Title
  
  Biochemical and Biophysical Research Communications 350 (3)
  
  Pages: 514-520
- Data Source
  KAKENHI-PROJECT-17700389
[Journal Article] Effect of photo-immobilization of epidermal growth factor on the cellular behaviors.2006
- Author(s)
  Ogiwara, K., Nagaoka, M., Cho, C.S., Akaike, T.
- Journal Title
  
  Biochemical and Biophysical Research Communications 345 (1)
  
  Pages: 255-259
- Data Source
  KAKENHI-PROJECT-17700389
[Journal Article] E-cadherin-coated plates maintain pluripotent ES cells without colony formation.2006
- Author(s)
  Nagaoka, M., Koshimizu, U., Yuasa, S., Hattori, F., Chen, H., Tanaka, T., Okabe, M., Fukuda, K., Akaike, T.
- Journal Title
  
  PLoS ONE 1
- Data Source
  KAKENHI-PROJECT-17700389
[Journal Article] Drastic effect of nanoapatite particles on liposome-mediated mRNA delivery to mammalian cells.2005
- Author(s)
  Zohra, F.T., Chowdhury, E.H., Nagaoka, M., Akaike, T
- Journal Title
  
  Analytical Biochemistry 345・1
  
  Pages: 164-166
- Data Source
  KAKENHI-PROJECT-17700389
[Journal Article] Integrin-supported fast rate intracellular delivery of plasmid DNA by extracellular matrix protein embedded calcium phosphate complexes.2005
- Author(s)
  Chowdhury, E.H., Nagaoka, M., Ogiwara, K., Zohra, F.T., Kutsuzawa, K., Tada, S., Kitamura, C., Akaike, T.
- Journal Title
  
  Biochemistry 44・37
  
  Pages: 12273-12278
- Data Source
  KAKENHI-PROJECT-17700389
[Journal Article] Role of E-cadherin molecules in spheroid formation of hepatocytes adhered on galactose-carrying polymer as an artificial asialoglycoprotein model.2005
- Author(s)
  Takei, R., Suzuki, D., Hoshiba, T., Nagaoka, M., Seo, S.J., Cho, C.S., Akaike, T.
- Journal Title
  
  Biotechnology Letters 27・16
  
  Pages: 1149-1156
- Data Source
  KAKENHI-PROJECT-17700389
[Journal Article] 再生医療・組織工学のためのバイオマテリアル2005
- Author(s)
  長岡正人, 赤池敏宏
- Journal Title
  
  繊維と工業(日本繊維学会誌) 61・6
  
  Pages: 139-141
- Data Source
  KAKENHI-PROJECT-17700389
[Journal Article] 材料表面修飾とティッシュエンジニアリング2005
- Author(s)
  荻原一隆, 長岡正人, 赤池敏宏
- Journal Title
  
  ティッシュエンジニアリング2005
  
  Pages: 77-83
- Data Source
  KAKENHI-PROJECT-17700389
[Journal Article] Construction of a novel extracellular matrix using a new genetically engineered epidermal growth factor fused to IgG-Fc.2005
- Author(s)
  Ogiwara, K., Nagaoka, M., Cho, C.S., Akaike, T.
- Journal Title
  
  Biotechnology Letters 27・20
  
  Pages: 1633-1637
- Data Source
  KAKENHI-PROJECT-17700389
[Presentation] ヒトiPS細胞株の違いによる融合タンパク質E-cad-Fc上での増殖性の検証2016
- Author(s)
  長岡正人
- Organizer
  第15回　日本再生医療学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-26870230
[Presentation] Fc融合タンパク質の幹細胞の維持・分化誘導への応用2016
- Author(s)
  長岡正人
- Organizer
  シンポジウム「細胞認識性バイオマテリアルと生体適合性バイオマテリアル」
- Place of Presentation
  CICセンター（東京工業大学田町キャンパス内）
- Year and Date
  2016-02-12
- Invited
- Data Source
  KAKENHI-PROJECT-26870230
[Presentation] 細胞認識性Fc融合タンパク質の作製と幹細胞培養への応用2015
- Author(s)
  長岡正人
- Organizer
  第4回　日本バイオマテリアル学会北陸地区若手研究会
- Place of Presentation
  石川ハイテク交流センター
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26870230
[Presentation] 融合タンパク質E-cad-Fcを用いたヒトiPS細胞の安定培養法の確立2015
- Author(s)
  長岡正人
- Organizer
  第37回　バイオマテリアル学会大会
- Place of Presentation
  京都テルサ
- Year and Date
  2015-11-09
- Data Source
  KAKENHI-PROJECT-26870230
[Presentation] Efficient Production and Purification of NCad-Fc-chimeric Protein-based Biomaterials for Application in Tissue-engineering and Regenerative medicine2013
- Author(s)
  Kutsuzawa K., Nag K., Nagaoka M., Akaike T.
- Organizer
  TERMIS-AP 2013 Annual Conference
- Place of Presentation
  Shanghai-Wuzhen, China
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Fc Chimeric Protein-based Biomaterials: Advancing Stem Cell Technology and Regenerative Medicine Toward Application2013
- Author(s)
  Nag K., Kutsuzawa K., Nagaoka M.,Yang J., Akaike T.
- Organizer
  TERMIS-AP 2013 Annual Conference
- Place of Presentation
  Shanghai-Wuzhen, China
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 固定化N-カドヘリンモデルによるP19細胞の分化制御2008
- Author(s)
  岳暁珊、田川陽一、赤池敏宏、竹内純、長岡正人
- Organizer
  第7回日本再生医療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-14
- Data Source
  KAKENHI-PROJECT-18300161
[Presentation] Design of Cell Recognition Biomaterials and Prospect for Development of Cadherin-Marices Engineering
- Author(s)
  Toshihiro Akaike, A. Haque, M. Nagaoka and Jun Yang
- Organizer
  2nd International Conference on Biomaterials Science in Tsukuba (ICBS2013)
- Place of Presentation
  つくば国際会議場（茨城県）
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Self-renewal and Differentiation of ES and iPS Cells on Bioengineered Surfaces: Novel Approach of Cell-Cooking Plate.
- Author(s)
  Toshihiro Akaike, Amranul Haque, Xiao-ShanYue, Masato Nagaoka,
- Organizer
  9th World Biomaterials Congress
- Place of Presentation
  Chengdu, China
- Invited
- Data Source
  KAKENHI-PROJECT-23220014

1. AKAIKE Toshihiro (30101207)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
2. TAGAWA Yoh-ichi (70262079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. OZEKI Eiichi (30192529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MIYAGAWA Shinichi (80229806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KOBATAKE Eiry (00225484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ISE Hirohiko (10324253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HARADA Ichiro (00361759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 賀喜白乙 (20515168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小林基弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGAOKA Masato 長岡 正人

Research Projects

Research Products

Co-Researchers

Analysis of expression profile of cell surface proteins, and establishment of specific cell adhesive materials for differentiation of human iPS cells into hepatic lineage cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of functions and differentiation of ES/iPS cells by designing cell-recognizable chimera matrices

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of Stem Cells Gene Expression using Apatite nanocarriers coated with Cell-reconizable chimeric Protein.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of super functional liver model based on developmental information

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規接着用マトリックス設計によるES細胞および各種幹細胞の高効率増幅と機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 再生医療の基礎シリーズ4「再生医療のためのバイオエンジニアリング・第5章 遺伝子工学手法に基づく新しい細胞マトリックス設計と再生医療への応用」2007

Author(s)

Publisher

Data Source

[Journal Article] Design of a vitronectin-based recombinant protein as a defined substrate for differentiation of human pluripotent stem cells into hepatocyte-like cells2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Direct observation of cell cycle progression in living mouse embryonic stem cell on an extracellular matrix of E-cadherin2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Control of Singular Cell Cycle Synchronization of Mouse ES Cells for Hepatocyte Differentiation on E-Cadherin Substratum2011

Author(s)

Journal Title

Data Source

[Journal Article] Application of Recombinant Fusion Proteins for Tissue Engineering.2010

Author(s)

Journal Title

Data Source

[Journal Article] An artificial extracellular matrix created by hepatocyte growth factor fused to IgG-Fc.2010

Author(s)

Journal Title

Data Source

[Journal Article] Design of the artificial acellular feeder layer for the efficient propagation of mouse ES cells2008

Author(s)

Journal Title

Data Source

[Journal Article] Embryonic Undifferentiated Cells Show Scattering Activity on a Surface Coated With Immobilized E-Cadherin.2008

Author(s)

Journal Title

Data Source

[Journal Article] Design of the artificial acellular feeder layer for the efficient propagation of mouse ES cells.2008

Author(s)

Journal Title

Data Source

[Journal Article] Design of Artificial Extracellular Matrices and Their Application for Regenerative Medicine.2008

Author(s)

Journal Title

Data Source

[Journal Article] Embryonic Undifferentiated Cells Show Scattering Activity on a Surface Coated With Immobilized E-Cadherin2008

Author(s)

Journal Title

Data Source

NAGAOKA Masato 長岡正人

[Book] 再生医療の基礎シリーズ4「再生医療のためのバイオエンジニアリング・第5章遺伝子工学手法に基づく新しい細胞マトリックス設計と再生医療への応用」2007