Mizuno Takuya 水野拓也

… Alternative Names

MIZUNO Takuya 水野拓也

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Researcher Number	90398826
Other IDs
Affiliation (Current)	2025: 山口大学, 共同獣医学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2025: 山口大学, 共同獣医学部, 教授 2012 – 2014: 山口大学, 獣医学部, 教授 2012 – 2013: 山口大学, 共同獣医学部, 教授 2011 – 2013: 山口大学, 農学部, 教授 2007 – 2011: Yamaguchi University, 農学部, 准教授 2005 – 2006: 山口大学, 農学部, 助教授
Review Section/Research Field	Principal Investigator Clinical veterinary science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Veterinary medical science / Basic Section 42020:Veterinary medical science-related / Basic veterinary science/Basic zootechnical science Except Principal Investigator Clinical veterinary science / Basic Section 52040:Radiological sciences-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Boundary agriculture
Keywords	Principal Investigator 犬 / 腫瘍 / がん / リンパ腫 / 抗体 / 免疫 / 抗体療法 / イヌ / 抗体医薬 / 抗体薬 … More / 免疫療法 / 悪性腫瘍 / 悪性黒色腫 / メラノーマ / キメラ抗原受容体 / 免疫細胞療法 / CAR-T / レオウイルス / 治療 / ガン / DNA vaccine / oncolytic virotherapy / immune checkpoint / cancer / dog / PSGL-1 / 新規治療法 / 内科 / 免疫介在性疾患 / レトロウイルス / NF-kappaB / シグナル / B細胞 … More Except Principal Investigator セラノスティクス / 悪性黒色種 / 放射線治療 / 温熱治療 / 有機シリカナノ粒子 / イヌ / アトピー性皮膚炎 / 細胞骨格 / 細胞内小器官 / がん免疫療法 / オーガンオンチップ / 膀胱がん / オルガノイド / セラノティクス / 悪性黒色腫 / セラノスティックス / RNA-seq / 診断マーカー / がん治療 / メラノーマ / 腫瘍マーカー / 口腔悪性黒色腫 / 内在性レトロウイルス / 樹状細胞 / NKT細胞 / 獲得免疫 / 自然免疫 / 癌ワクチン / ケラチノサイト / トランスレーショナルリサーチ / 獣医学 / アレルギー・ぜんそく / Argos衛星 / ニパウイルス / 発信機 / 新興・再興感染症 / 東南アジア / 環境計測 / テレメトリー / オオコウモリ / 国際情報交換 / 環境 / ウイルス / 新興感染症 / コウモリ / アトピー性皮膚 / IgE / 動物モデル Less

犬口腔内メラノーマの腫瘍免疫シグネチャの層別化に基づく複合治療法の開発と実践Principal Investigator
- Principal Investigator
  
  水野拓也
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Yamaguchi University
Elucidation of the mechanism of cancer progression and acquisition of resistance to therapy by utilizing bladder organoids derived from urine samples.
- Principal Investigator
  
  臼井達哉
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Tokyo University of Agriculture and Technology
Creation of Nanomulti sensitization cascade radiotherapy against the cytoskeleton and intracellular organelles
- Principal Investigator
  
  中村教泰
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Yamaguchi University
リバーストランスレーショナル研究による犬メラノーマに対する最適な免疫療法の確立Principal Investigator
- Principal Investigator
  
  水野拓也
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Yamaguchi University
Development and demonstration of a universal antibody drug actively working against canine malignancies.Principal Investigator
- Principal Investigator
  
  Mizuno Takuya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Yamaguchi University
Development of hyperthermia radiation multi-theranostics nanoparticles highly accumulated in malignant melanoma
- Principal Investigator
  
  Nakamura Michihiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Yamaguchi University
Functional analyses of endogenous retroviruses expressed in melanoma and their application in veterinary clinical practice.
- Principal Investigator
  
  Miyazawa Takayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Kyoto University
Establishment of a novel CAR-T therapy for canine melanomaPrincipal Investigator
- Principal Investigator
  
  Mizuno Takuya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Yamaguchi University
Development of the combined immune-modulatory therapies for canine cancerPrincipal Investigator
- Principal Investigator
  
  MIZUNO TAKUYA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Yamaguchi University
Identification of targeted antigen for the treatment of canine T cell lymphoma by using multiple immunization.Principal Investigator
- Principal Investigator
  
  Mizuno Takuya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Veterinary medical science
- Research Institution
  Yamaguchi University
Analysis of the genes expressed in canine lymphoma using in vitro and in vivo methodology.Principal Investigator
- Principal Investigator
  
  TAKUYA Mizuno
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Yamaguchi University
Is "steric hindrance effect" the possible new concept for tumor metastasis mechanism?Principal Investigator
- Principal Investigator
  
  MIZUNO Takuya
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Clinical veterinary science
- Research Institution
  Yamaguchi University
The mechanism of activation of Langerhans cells mediated by keratinocytes
- Principal Investigator
  
  MAEDA SADATOSHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Gifu University
Development of a new type of cancer vaccine for dog malignancy
- Principal Investigator
  
  SHIMIZU Kanako
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  The Institute of Physical and Chemical Research
Fundamental research for development of new therapy for canine lymphomaPrincipal Investigator
- Principal Investigator
  
  MIZUNO Takuya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Yamaguchi University
Development of a novel therapy for canine atopic dermatitis with chimera IgG of anti-canine IgE antibody
- Principal Investigator
  
  MAEDA Sadatoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Gifu University
Prediction of emerging infectious diseases mediated by the bat as the reservoir.
- Principal Investigator
  
  HONDO Eiichi
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Boundary agriculture
- Research Institution
  Nagoya University
  Yamaguchi University
Development and clinical appliance of molecular target therapy for immune-mediated disease in dogs.Principal Investigator
- Principal Investigator
  
  MIZUNO Takuya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Yamaguchi University
B細胞のT細胞保存性免疫応答に対するレセプターからのクロストーク機構の解明Principal Investigator
- Principal Investigator
  
  水野拓也
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Yamaguchi University

[Journal Article] Proof-of-concept study of the caninized anti-canine programmed death 1 antibody in dogs with advanced non-oral malignant melanoma solid tumors2024
- Author(s)
  Igase Masaya、Inanaga Sakuya、Nishibori Shoma、Itamoto Kazuhito、Sunahara Hiroshi、Nemoto Yuki、Tani Kenji、Horikirizono Hiro、Nakaichi Munekazu、Baba Kenji、Kambayashi Satoshi、Okuda Masaru、Sakai Yusuke、Sakurai Masashi、Kato Masahiro、Tsukui Toshihiro、Mizuno Takuya
- Journal Title
  
  Journal of Veterinary Science
  
  Volume: 25 Issue: 1
- DOI
  10.4142/jvs.23144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04754
[Journal Article] Surface Functionalization of Organosilica Nanoparticles With Au Nanoparticles Inhibits Cell Proliferation and Induces Cell Death in 4T1 Mouse Mammary Tumor Cells for DNA and Mitochondrial-Synergized Damage in Radiotherapy2022
- Author(s)
  Mochizuki Chihiro、Kayabe Yukihito、Nakamura Junna、Igase Masaya、Mizuno Takuya、Nakamura Michihiro
- Journal Title
  
  Frontiers in Chemistry
  
  Volume: 10 Pages: 907642-907642
- DOI
  10.3389/fchem.2022.907642
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03625
[Journal Article] Systematic Identification of Endogenous Retroviral Protein-Coding Genes Expressed in Canine Oral Malignant Melanoma2021
- Author(s)
  Kitao Koichi、Sumiyoshi Aoi、Nakagawa So、Matsumoto Yuki、Mizuno Takuya、Miyazawa Takayuki
- Journal Title
  
  Frontiers in Virology
  
  Volume: 1 Pages: 1-11
- DOI
  10.3389/fviro.2021.785678
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22365, KAKENHI-PROJECT-20J22607, KAKENHI-PROJECT-20K06775
[Journal Article] Near-Infrared Fluorescent Thiol-Organosilica Nanoparticles That Are Functionalized with IR-820 and Their Applications for Long-Term Imaging of in Situ Labeled Cells and Depth-Dependent Tumor in Vivo Imaging2020
- Author(s)
  Nakamura Michihiro、Hayashi Koichiro、Nakamura Junna、Mochizuki Chihiro、Murakami Takuya、Miki Hirokazu、Ozaki Shuji、Abe Masahiro
- Journal Title
  
  Chemistry of Materials
  
  Volume: 32 Issue: 17 Pages: 7201-7214
- DOI
  10.1021/acs.chemmater.0c01414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22534, KAKENHI-PROJECT-19K22970, KAKENHI-PROJECT-20K15322, KAKENHI-PROJECT-20H03625
[Journal Article] Optimization of canine CD20 chimeric antigen receptor T cell manufacturing and in vitro cytotoxic activity against B‐cell lymphoma2020
- Author(s)
  Sakai Osamu、Igase Masaya、Mizuno Takuya
- Journal Title
  
  Veterinary and Comparative Oncology
  
  Volume: 18 Issue: 4 Pages: 739-752
- DOI
  10.1111/vco.12602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680, KAKENHI-PROJECT-18H02347
[Journal Article] Establishment and Characterization of Monoclonal Antibody Against Canine CD8 Alpha2020
- Author(s)
  Sakai Osamu、Ii Tatsuhito、Uchida Kazuyuki、Igase Masaya、Mizuno Takuya
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 39 Issue: 4 Pages: 129-134
- DOI
  10.1089/mab.2020.0002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15680, KAKENHI-PROJECT-18H02347
[Journal Article] Development and characterization of monoclonal antibodies against canine PD-1 and PD-L1.2018
- Author(s)
  Nemoto Y, Shosu K, Okuda M, Noguchi S, Mizuno T.
- Journal Title
  
  Vet Immunol Immunopathol
  
  Volume: 198 Pages: 19-25
- DOI
  10.1016/j.vetimm.2018.02.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04598, KAKENHI-PROJECT-18K14588
[Journal Article] Oncolytic reovirus therapy: Pilot study in dogs with spontaneously occurring tumours.2018
- Author(s)
  Hwang CC, Igase M, Sakurai M, Haraguchi T, Tani K, Itamoto K, Shimokawa T, Nakaichi M, Nemoto Y, Noguchi S, Coffey M, Okuda M, Mizuno T.
- Journal Title
  
  Vet Comp Oncol.
  
  Volume: - Issue: 2 Pages: 229-238
- DOI
  10.1111/vco.12361
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04598
[Journal Article] Bosutinib, an SRC inhibitor, induces caspase-independent cell death associated with permeabilization of lysosomal membranes in melanoma cells.2017
- Author(s)
  Noguchi S, Shibutani S, Fukushima K, Mori T, Igase M, Mizuno T.
- Journal Title
  
  Vet Comp Oncol
  
  Volume: 印刷中 Issue: 1 Pages: 69-76
- DOI
  10.1111/vco.12312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18530, KAKENHI-PROJECT-15H04598
[Journal Article] Oncolytic reovirus synergizes with chemotherapeutic agents to promote cell death in canine mammary gland tumor2016
- Author(s)
  Igase M, Hwang CC, Kambayashi S, Kubo M, Coffey M, Miyama TS, Baba K, Okuda M, Noguchi S, Mizuno T
- Journal Title
  
  Can J Vet Res.
  
  Volume: 80 Pages: 21-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04598
[Journal Article] Programmed Cell Death Ligand 1 Expression in Canine Cancer.2016
- Author(s)
  Shosu K, Sakurai M, Inoue K, Nakagawa T, Sakai H, Morimoto M, Okuda M, Noguchi S, Mizuno T.
- Journal Title
  
  In Vivo
  
  Volume: 30 Pages: 195-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04598
[Journal Article] Oncolytic effects of reovirus in canine solid tumor cell lines.2015
- Author(s)
  Igase M, Hwang CC, Coffey M, Okuda M, Noguchi S, Mizuno T.
- Journal Title
  
  J Vet Med Sci. 2015 Jan16[Epub ahead of print]
  
  Volume: 印刷中
- NAID
  130005071879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380170
[Journal Article] Analysis of microRNA-203 function in CREB/MITF/RAB27a pathway: comparison between canine and human melanoma cells.2015
- Author(s)
  Noguchi S, Kumazaki M, Mori T, Baba K, Okuda M, Mizuno T, Akao Y.
- Journal Title
  
  Vet Comp Oncol.
  
  Volume: 印刷中 Issue: 4 Pages: 384-394
- DOI
  10.1111/vco.12118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380170
[Journal Article] The effects of oncolytic reovirus in canine lymphoma cell lines.2015
- Author(s)
  Hwang CC, Umeki S, Igase M, Coffey M, Noguchi S, Okuda M, Mizuno T.
- Journal Title
  
  Vet Comp Oncol.
  
  Volume: 印刷中 Issue: S1 Pages: 61-73
- DOI
  10.1111/vco.12124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380170
[Journal Article] Investigation of the cytotoxic effect of flavopiridol in canine lymphoma cell lines.2015
- Author(s)
  Ema Y, Igase M, Takeda Y, Yanase T, Umeki S, Hiraoka H, Okuda M, Mizuno T.
- Journal Title
  
  Vet Comp Oncol.
  
  Volume: 印刷中 Issue: S1 Pages: 95-106
- DOI
  10.1111/vco.12130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380170
[Journal Article] Regulation of the development of asthmatic inflammation by in situ CD4(+)Foxp3 (+) T cells in a mouse model of late allergic asthma.2014
- Author(s)
  Nakashima T, Hayashi T, Mizuno T.
- Journal Title
  
  Inflammation
  
  Volume: 37(5) Issue: 5 Pages: 1642-1653
- DOI
  10.1007/s10753-014-9892-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380170
[Journal Article] Reovirus type-2-triggered autoimmune cholangitis in extrahepatic bile ducts of weanling DBA/1J mice2014
- Author(s)
  Nakashima T, Hayashi T, Tomoeda S, Yoshino M, Mizuno T
- Journal Title
  
  Pediatr Res
  
  Volume: 75(1-1) Pages: 29-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Seroepidemiology of Reovirus in Healthy Dogs in Six Prefectures in Japan.2014
- Author(s)
  Hwang CC, Mochizuki M, Maeda K, Okuda M, Mizuno T.
- Journal Title
  
  J Vet Med Sci.
  
  Volume: 76 (3) Pages: 471-475
- NAID
  130003382393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380170
[Journal Article] Seroepidemiology of Reovirus in Healthy Dogs in Six Prefectures in Japan2014
- Author(s)
  Hwang CC, Mochizuki M, Maeda K, Okuda M, Mizuno T
- Journal Title
  
  J Vet Med Sci
  
  Volume: 76(3) Pages: 471-475
- NAID
  130003382393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Establishment of Five Canine Lymphoma Cell Lines and Tumor Formation in a Xenotransplantation Model2013
- Author(s)
  Umeki, S., Ema, Y., Suzuki, R., Kubo, M., Hayashi, T., Okamura, Y., Yamazaki, J., Tsujimoto, H., Tani, K., Hiraoka, H., Okuda, M. and Mizuno, T
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 75 Issue: 4 Pages: 467-474
- DOI
  10.1292/jvms.12-0448
- NAID
  130002502194
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380182, KAKENHI-PROJECT-24380170, KAKENHI-PROJECT-24580460, KAKENHI-PROJECT-24658265
[Journal Article] Anti-adhesive property of P-selectin glycoprotein ligand-1 (PSGL-1) due to steric hindrance effect2013
- Author(s)
  Umeki S, Suzuki R, Ema Y, Shimojima M, Nishimura Y, Okuda M, Mizuno T
- Journal Title
  
  J Cell Biochem
  
  Volume: 114(6) Pages: 1271-1285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Anti-adhesive property of P-selectin glycoprotein ligand-1 (PSGL-1)due to steric hindrance effect.2013
- Author(s)
  Umeki S, Suzuki R, Ema Y, Shimojima N, Nishinura Y, Okuda M, Mizuno T.
- Journal Title
  
  J Cell Biochem.
  
  Volume: 114 (6) Issue: 6 Pages: 1271-1285
- DOI
  10.1002/jcb.24468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380170, KAKENHI-PROJECT-24658268
[Journal Article] Oncolytic reovirus in canine mast cell tumor.2013
- Author(s)
  Hwang CC, Umeki S, Kubo M, Hayashi T, Shimoda H, Mochizuki M, Maeda K, Baba K, Hiraoka H, Coffey M, Okuda M, Mizuno T.
- Journal Title
  
  PLoS ONE
  
  Volume: 8(9)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380170
[Journal Article] Vaccination with antigen-transfected, NKT cell ligand-loaded, human cells elicits robust in situ immune responses by dendritic cells2013
- Author(s)
  Shimizu K, Mizuno T, Shinga J, Asakura M, Kakimi K, Ishii Y, Masuda K, Maeda T, Sugahara H, Sato Y, Matsushita H, Nishida K, Hanada KI, Dörrie J, Schaft N, Bickham K, Koike H, Ando T, Nagai R, Fujii SI
- Journal Title
  
  Cancer Res
  
  Volume: 73(1) Pages: 62-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Vaccination with antigen-transfected, NKT cell ligand-loaded, human cells elicits robust in situ immune responses by dendritic cells2013
- Author(s)
  Shimizu K, Mizuno T, Shinga J, Asakura M, Kakimi K, Ishii Y, Masuda K, Maeda T, Sugahara H, Sato Y, Matsushita H, Nishida K, Hanada KI, Dörrie J, Schaft N, Bickham K, Koike H, Ando T, Nagai R, Fujii S
- Journal Title
  
  Cancer Res
  
  Volume: 73 Pages: 62-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380186
[Journal Article] Vaccination with antigen-transfected, NKT cell ligand-loaded, human cells elicits robust in situ immune responses by dendritic cells.2013
- Author(s)
  Shimizu K, Mizuno T, Shinga J, Asakura M, Kakimi K, Ishii Y, Masuda K, Maeda T, Sugahara H, Sato Y, Matsushita H, Nishida K, Hanada K, Dorrie J, Schaft N, Bickham K, Koike H, Ando T, Nagai R, Fujii S.
- Journal Title
  
  Cancer Res.
  
  Volume: 73(1) Issue: 1 Pages: 62-73
- DOI
  10.1158/0008-5472.can-12-0759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300332, KAKENHI-PROJECT-23380186, KAKENHI-PROJECT-23590576, KAKENHI-PROJECT-24249028, KAKENHI-PROJECT-24501329
[Journal Article] Establishment of Five Canine Lymphoma Cell Lines and Tumor Formation in a Xenotransplantation Model.2013
- Author(s)
  Umeki S, Ema Y, Suzuki R, Kubo M, Hayashi T, Okamura Y, Yamazaki J, Tsujimoto H, Tani K, Hiraoka H, Okuda M, Mizuno T.
- Journal Title
  
  J Vet Med Sci.
  
  Volume: -
- NAID
  130002502194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Oncolytic reovirus in canine mast cell tumor2013
- Author(s)
  Hwang CC, Umeki S, Kubo M, Hayashi T, Shimoda H, Mochizuki M, Maeda K, Baba K, Hiraoka H, Coffey M, Okuda M, Mizuno T
- Journal Title
  
  PLoS ONE
  
  Volume: 8(9)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] A Potential Therapeutic Application of SET/I2PP2A Inhibitor OP449 for Canine T-Cell Lymphoma2013
- Author(s)
  Fujiwara N, Kawasaki H, Yabe R, Christensen DJ, Vitek MP, Mizuno T, Sato K, Ohama T
- Journal Title
  
  J Vet Med Sci
  
  Volume: 75(3) Pages: 349-354
- NAID
  130001879628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Reovirus type-2 infection in newborn DBA/1J mice reduces the development of late allergic asthma2012
- Author(s)
  Nakashima T, Hayashi T, Mizuno T
- Journal Title
  
  Int J Exp Patho
  
  Volume: 93(3) Pages: 234-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Administration of interferon (IFN)-αexacerbates Reovirus type-2-triggered autoimmune insulitis in DBA/1J mice2012
- Author(s)
  Nakashima T, Hayashi T, Yamamoto Y, Mizuno T
- Journal Title
  
  Scand J Immunol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Feline infectious peritonitis virus with a large deletion in the 5'-terminal region of the spike gene retains its virulence for cats2012
- Author(s)
  Terada Y, Shiozaki Y, Shimoda H, Mahmoud HY, Noguchi K, Nagao Y, Shimojima M, Iwata H, Mizuno T, Okuda M, Morimoto M, Hayashi T, Tanaka Y, Mochizuki M, Maeda K
- Journal Title
  
  J Gen Virol
  
  Volume: 93(Pt 9) Pages: 1930-934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Destruction of salivary and lacrimal glands by Th1-polarized reaction in a model of secondary Sjogren's syndrome in lupus-prone female NZB x NZWF(1) mice2012
- Author(s)
  Hayashi T, Shimoyama N, Mizuno T
- Journal Title
  
  Inflammation
  
  Volume: 35 (2) Pages: 638-646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Calreticulin expression in neoplastic versus normal dog mammary glands : A cDNA subtraction-based study2012
- Author(s)
  Okawa T, Kurio Y, Morimoto M, Hayashi T, Nakagawa T, Sasaki N, Okuda M, Mizuno T
- Journal Title
  
  Res. Vet. Sci
  
  Volume: 92(1) Pages: 80-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Calreticulin expression in neoplastic versus normal dog mammary glands : A cDNA subtraction-based study2012
- Author(s)
  Okawa T, Kurio Y, Morimoto M, Hayashi T, Nakagawa T, Sasaki N, Okuda M, Mizuno T
- Journal Title
  
  Res Vet Sci
  
  Volume: 92(1) Pages: 80-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] Neutropenia Associated with Osteomyelitis due to Hepatozoon canis Infection in a Dog2012
- Author(s)
  Shimokawa Miyama T, Umeki S, Baba K, Sada K, Hiraoka H, Endo Y, Inokuma H, Hisasue M, Okuda M, Mizuno T
- Journal Title
  
  J Vet Med Sci
  
  Volume: 73(10) Pages: 1389-93
- NAID
  130000868268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] Calreticulin expression in neoplastic versus normal dog mammary glands : A cDNA subtraction-based study2012
- Author(s)
  Okawa T, Kurio Y, Morimoto M, Hayashi T, Nakagawa T, Sasaki N, Okuda M,-Mizuno, T
- Journal Title
  
  Res Vet Sci
  
  Volume: 92 Pages: 80-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] Establishment of Five Canine Lymphoma Cell Lines and Tumor Formation in a Xenotransplantation Model2012
- Author(s)
  Umeki S, Ema Y, Suzuki R, Kubo M, Hayashi T, Okamura Y, Yamazaki J, Tsujimoto H, Tani K, Hiraoka H, Okuda M, Mizuno T
- Journal Title
  
  J Vet Med Sci
- NAID
  130002502194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Development of High-Grade B-Cell Lymphoma Concurrent with T-Cell Chronic Lymphocytic Leukemia in a Dog2012
- Author(s)
  Okawa T, Hiraoka H, Wada Y, Baba K, Itamoto K, Mizuno T, Okuda M
- Journal Title
  
  J Vet Med Sci
  
  Volume: 74(5) Pages: 677-80
- NAID
  130001879878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Ehrlichia canis Infection in Two Dogs that Emigrated from Endemic Areas2012
- Author(s)
  Baba K, Itamoto K, Amimoto A, Kitagawa K, Hiraoka H, Mizuno T, Sato H, Okuda M
- Journal Title
  
  J Vet Med Sci
  
  Volume: 74(6) Pages: 775-778
- NAID
  130002090067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24658268
[Journal Article] Characterization of monoclonal antibodies against canine P-selectin glycoprotein ligand-1(PSGL-1)2011
- Author(s)
  Umeki S, Suzuki R, Shimojima M, Ema Y, Yanase T, Iwata H, Okuda M, Mizuno T
- Journal Title
  
  Vet Immunol Immunopathol
  
  Volume: 142(1-2) Pages: 119-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] Prekallikrein Deficiency in a Dog2011
- Author(s)
  Okawa T, Yanase T, Shimokawa Miyama T, Hiraoka H, Baba K, Tani K, Okuda M, Mizuno T
- Journal Title
  
  J Vet Med Sci
  
  Volume: 73(1) Pages: 107-11
- NAID
  130000307711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] 東南アジア・オセアニアのオオコウモリの行動2011
- Author(s)
  本道栄一、寺川純平、杉山真言、水野拓也、前田健
- Journal Title
  
  山口県獣医師会雑誌
  
  Pages: 31-44
- NAID
  220000138780
- Data Source
  KAKENHI-PROJECT-20405049
[Journal Article] Destruction of salivary and lacrimal glands by T1 polarized reaction in a model of secondary Sjogren' s Syndrome in lupus-prone female NZB_xNZWF_1 mice.2011
- Author(s)
  Hayashi T, Shimoyama N, Mizuno T.
- Journal Title
  
  Inflammation
  
  Volume: (In press) Issue: 2 Pages: 638-646
- DOI
  10.1007/s10753-011-9356-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580362, KAKENHI-PROJECT-23380186
[Journal Article] Neutropenia Associated with Osteomyelitis due to Hepatozoon canis Infection in a Dog2011
- Author(s)
  Shimokawa Miyama T, Umeki S, Baba K, Sada K, Hiraoka H, Endo Y, Inokuma H, Hisasue M, Okuda M, Mizuno T
- Journal Title
  
  J Vet Med Sci
  
  Volume: 73 Pages: 1389-1393
- NAID
  130000868268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] Characterization of monoclonal antibodies against canine P-selectin glycoprotein ligand-1 (PSGL-1)2011
- Author(s)
  Umeki S, Suzuki R, Shimojima M, Ema Y, Yanase T, Iwata H, Okuda M, Mizuno T
- Journal Title
  
  Vet Immunol Immunopathol
  
  Volume: 142 Pages: 119-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] Anti-human very late antigen-alpha4(CD49d) monoclonal antibody(BU49) cross-reacts with the canine B-cell leukemia cell line GL-12010
- Author(s)
  Ikewaki N, Nakaichi M, Mizuno T, Takamura N, Tokunaga J, Ogata K, Inoko H, Otsu R
- Journal Title
  
  resulting in the induction of homotypic cell aggregation. Cell Immunol
  
  Volume: 263(1) Pages: 55-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] Molecular cloning of canine interleukin-31 and its expression in various tissues2009
- Author(s)
  Mizuno T, et.al.
- Journal Title
  
  Veterinary Immunology and Immunopathology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780232
[Journal Article] Superficial necrolytic dermatitis associated with extrapancreatic glucagonoma in a dog2009
- Author(s)
  Mizuno T, et.al.
- Journal Title
  
  Veterinary Dermatology 20
  
  Pages: 72-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780232
[Journal Article] Crossreactivity of antibodies to canine CD25 and Foxp3 and identification of canine CD4+ CD25+ Foxp3+ cells in canine peripheral blood2009
- Author(s)
  Mizuno T, Suzuki R, Umeki S, Okuda M
- Journal Title
  
  J Vet Med Sci
  
  Volume: 71(12) Pages: 1561-1568
- NAID
  130000149981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] Molecular cloning of canine interleukin-31 and its expression in various tissues2009
- Author(s)
  Mizuno T, Kanbayashi S, Okawa T, Maeda S, Okuda M
- Journal Title
  
  Vet Immunol Immunopathol
  
  Volume: 131(1-2) Pages: 140-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] Molecular cloning of canine interleukin-31 and its expression in various tissues2009
- Author(s)
  Takuya Mizuno、Satoshi Kanbayashi、Takumi Okawa、Sadatoshi Maeda、Masaru Okuda
- Journal Title
  
  Vet Immunol Immunopathol. 131
  
  Pages: 140-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380172
[Journal Article] Molecular cloning of canine interleukin-31 and its expression in various tissues.2009
- Author(s)
  Mizuno T., et al.
- Journal Title
  
  Vet Immunol Immunopathol
  
  Volume: 131(1-2) Pages: 140-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] Crossreactivity of antibodies to canine CD25 and Foxp3 and identification of canine CD4+CD25+Foxp3+ cells in canine peripheral blood.2009
- Author(s)
  Mizuno T., et al.
- Journal Title
  
  J Vet Med Sci
  
  Volume: 71(12) Pages: 1561-1568
- NAID
  130000149981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] Magnetic resonance imaging and clinical findings in a miniature Schnauzer with hypodipsic hypernatremia2009
- Author(s)
  Shimokawa Miyama T, Iwamoto E, Umeki S, Nakaichi M, Okuda M, Mizuno T
- Journal Title
  
  J Vet Med Sci
  
  Volume: 71(10) Pages: 1387-1391
- NAID
  130000134306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21688022
[Journal Article] タイ国におけるオオコウモリの調査2008
- Author(s)
  本道栄一、前田健、水野拓也、竹松葉子、脇谷晶一、寺川純平、Thanmaporn Phichitraslip、木曾康、Prateep Duengkae、Worawut Rerkamnuaychoke
- Journal Title
  
  山口県獣医師会雑誌
- NAID
  40016699145
- Data Source
  KAKENHI-PROJECT-20405049
[Journal Article] アナフィラキシー2007
- Author(s)
  水野拓也
- Journal Title
  
  Companion Animal Practice 225
  
  Pages: 56-63
- Data Source
  KAKENHI-PROJECT-19780232
[Journal Article] フローサイトメトリーの原理と臨床応用2007
- Author(s)
  水野拓也
- Journal Title
  
  Companion Animal Practice 218
  
  Pages: 53-63
- Data Source
  KAKENHI-PROJECT-19780232
[Journal Article] 液性免疫とIgE産生のメカニズム2006
- Author(s)
  水野拓也
- Journal Title
  
  Companion Animal Practice 208
  
  Pages: 7-15
- Data Source
  KAKENHI-PROJECT-17780222
[Journal Article] Genomic cloning of feline Fas ligand gene and characterization of the transcription regulatory region2006
- Author(s)
  Takuya Mizuno
- Journal Title
  
  Veterinary Immunology and Immunopathology 114・3-4
  
  Pages: 305-312
- Data Source
  KAKENHI-PROJECT-17780222
[Journal Article] Experimental inoculation of beagle dogs with Ehrlichia species detected from lxodes ovatus.2006
- Author(s)
  Watanabe M, Oikawa T, Hiraoka H, Kaneko N, Itamoto K, Mizuno T, Okuda M, Inokuma H.
- Journal Title
  
  Veterinary Parasitology 136・2
  
  Pages: 147-147
- Data Source
  KAKENHI-PROJECT-17780222
[Journal Article] Cloning of the feline GADD45 cDNA and analysis of its mutation in feline lymphoma cell lines2006
- Author(s)
  Oikawa T, Okuda M, Kaneko N, Watanabe M, Hiraoka H, Itamoto K, Nakaichi M, Mizuno T, Inokuma H
- Journal Title
  
  Journal of veterinary medical sciences 68・3
  
  Pages: 297-297
- NAID
  130000447940
- Data Source
  KAKENHI-PROJECT-17780222
[Journal Article] The mechanisms of immune-mediated disorders in dogs.2006
- Author(s)
  Takuya Mizuno
- Journal Title
  
  Journal of Small Animal Medicine 8・4
  
  Pages: 4-15
- Data Source
  KAKENHI-PROJECT-17780222
[Journal Article] B cell receptor (BCR) cross-talk : CD40 engagement creates and alternate pathway for BCR signaling that activates I kappaB kinase/I kappaB alpha/NF-kappaB without the need for PI3K and PLC gamma.2005
- Author(s)
  Mizuno T, Rothstein TL
- Journal Title
  
  Journal of Immunology 174・10
  
  Pages: 6062-6062
- Data Source
  KAKENHI-PROJECT-17780222
[Presentation] Antibody based immunotherapy for canine cancers2024
- Author(s)
  Takuya Mizuno
- Organizer
  World Veteriary Cancer Conference 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04754
[Presentation] イヌメラノーマで高発現する内在性レトロウイルス由来遺伝子の探索2019
- Author(s)
  北尾晃一、水野拓也、中川草、宮沢孝幸
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K22365
[Presentation] Establishment of monoclonal antibody against canine CD20 chimeric antigen receptor T cells2019
- Author(s)
  Sakai O, Inase M, Mizuno T
- Organizer
  The 6th Asian Meeting of Animal Medicine Specialties
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02347
[Presentation] Development of therapeutic antibody for canine cancers.2018
- Author(s)
  Mizuno T.
- Organizer
  The 9th Joint Symposium of Veterinary Research in East Asia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04598
[Presentation] Inhibition of the ATM enhaned the reovirus-induced cell death in canine melanoma cells.2017
- Author(s)
  Igase M, Mizuno T.
- Organizer
  The 5th Sapporo Summer Seminar for One Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04598
[Presentation] ATM kinase阻害による犬メラノーマ細胞株に対する腫瘍溶解性ウイルスの細胞傷害増強効果の検討2017
- Author(s)
  伊賀瀬雅也、野口俊助、根本有希、水野拓也
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04598
[Presentation] ATM kinaseの阻害は、犬の悪性黒色腫細胞株においてレオウイルスの細胞死を促進する2017
- Author(s)
  伊賀瀬雅也、野口俊助、水野拓也
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04598
[Presentation] Pilot study of oncolytic reovirus therapy in dogs with spontaneouasly occurring tumors.2017
- Author(s)
  Igase M, Hwang CC, Sakurai M, Shimokawa T, Haraguchi T, Tani K, Itamoto K, Nakaichi M, Nemoto Y, Shimokawa T, Okuda M, Noguchi S, Mizuno T.
- Organizer
  Asian Meeting of Animal Medicine Specialties 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04598
[Presentation] Reovirus induces poptotic cell death by the dysregulation of the Ras signling pathway2014
- Author(s)
  Hwang Chung Chew、伊賀瀬雅也、下川孝子、馬場健司、奥田優、野口俊助、水野拓也
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] 腫瘍溶解性ウイルスによる犬乳腺腫瘍細胞に対する抗腫瘍効果の検討2014
- Author(s)
  伊賀瀬雅也、Chung Chew Hwang、久保正仁、中嶋朋美、林俊春、馬場健司、野口俊助、奥田優、水野拓也
- Organizer
  日本獣医内科学アカデミー第10回記念学術大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] イヌのPD-1およびPD-L1に対するモノクローナル抗体の作製とその機能の解析2014
- Author(s)
  正司麗葉、伊賀瀬雅也、下川孝子、馬場健司、奥田優、野口俊助、水野拓也
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] 犬乳腺腫瘍細胞株に対する腫瘍溶解性ウイルス療法と化学療法の併用による相乗効果の検討2014
- Author(s)
  伊賀瀬雅也、Hwang Chung Chew、上林聡之、下川孝子、馬場健司、奥田優、野口俊助、水野拓也
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] イヌのリンパ腫において過剰発現する遺伝子IL-37の解析2013
- Author(s)
  片山貴朗、柳瀬拓磨、藤原亜紀、辻本元、奥田優、水野拓也
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学(岐阜市)
- Year and Date
  2013-09-21
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] イヌインターフェロンガンマによる犬腫瘍細胞株の増殖抑制効果の検討2013
- Author(s)
  濱村友紀、奥田優、水野拓也
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学(岐阜市)
- Year and Date
  2013-09-21
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] レオウイルスによる犬の各種腫瘍細胞株に対する細胞死の誘導2013
- Author(s)
  伊賀瀬雅也、Chung Chew Hwang、奥田優、水野拓也
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学(岐阜市)
- Year and Date
  2013-09-21
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] レオウイルスによる犬の各種腫瘍細胞株に対する細胞死の誘導2013
- Author(s)
  伊賀瀬雅也、Chung Chew Hwang、奥田優、水野拓也
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学（岐阜市）
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] 日本国内の主要犬種における犬白血球抗原I型の遺伝子解析2013
- Author(s)
  中谷亮太、井上公美、川野浩志、奥田優、水野拓也
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学（岐阜市）
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] Reovirus effectively induces oncolysis in canine mast cell tumor in vivo and ex vivo Chung Chew Hwang2013
- Author(s)
  梅城沙織、伊賀瀬雅也、久保正仁、林俊春、奥田優、水野拓也
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学(岐阜市)
- Year and Date
  2013-09-21
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] Reovirus effectively induces oncolysis in canine mast cell tumor in vivo and ex vivo2013
- Author(s)
  Chung Chew Hwang、梅城沙織、伊賀瀬雅也、久保正仁、林俊春、奥田優、水野拓也
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学（岐阜市）
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] イヌインターフェロンガンマによる犬腫瘍細胞株の増殖抑制効果の検討2013
- Author(s)
  濱村友紀、奥田優、水野拓也
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学（岐阜市）
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] 人工アジュバントベクター細胞を用いた犬の腫瘍免疫療法の前臨床試験2013
- Author(s)
  水野拓也、清水佳奈子、垣見和宏、藤井眞一郎
- Organizer
  獣医アトピー・アレルギー・免疫学会第7回シンポジウム症例報告
- Place of Presentation
  国際ファッションセンター3F KFCホールアネックス(東京都))
- Year and Date
  2013-01-13
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] 日本国内の主要犬種における犬白血球抗原I型の遺伝子解析2013
- Author(s)
  中谷亮太、井上公美、川野浩志、奥田優、水野拓也
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学(岐阜市)
- Year and Date
  2013-09-21
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] 新しく樹立したイヌリンパ腫細胞株のin vitroおよびin vivoにおける性状解析2012
- Author(s)
  梅城沙織、江馬康夫、鈴木綾一、久保正仁，林俊春、岡村泰彦、山崎淳平、辻本元、谷健二、平岡博子、奥田優、水野拓也
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学（盛岡市）
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] Discovering the oncolytic potential of reovirus in veterinary medicine : reovi rus-induced cell death in canine lymphoma and last cell tumor ceell lines2012
- Author(s)
  Hwang Chung Chew、梅城沙織、中川貴之、下田宙、望月雅美、前田健、平岡博子、奥田優、水野拓也
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学(盛岡市)
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] イヌのリンパ腫において過剰発現する遺伝子の解析2012
- Author(s)
  柳瀬拓磨、梅城沙織、酒井治、平岡博子、藤原亜紀、辻本元、奥田優、水野拓也
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学(盛岡市)
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] イヌのWT-1に対する抗体の特異性の解析2012
- Author(s)
  酒井治、中谷亮太、梅城沙織、酒井洋樹、久保正仁、森本将弘、林俊春、平岡博子、奥田優、水野拓也
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学(盛岡市
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] 免疫抑制に用いる治療薬2012
- Author(s)
  水野拓也
- Organizer
  第15回日本獣医皮膚科学会学術大会
- Place of Presentation
  大宮ソニックシティ(埼玉)
- Year and Date
  2012-03-18
- Data Source
  KAKENHI-PROJECT-21688022
[Presentation] イヌのリンパ腫において過剰発現する遺伝子の解析2012
- Author(s)
  柳瀬拓磨、梅城沙織、酒井治、平岡博子、藤原亜紀、辻本元、奥田優、水野拓也
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学（盛岡市）
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] Vaccination with mRNA-transfected, NKT cell ligand-loaded, human vector cells elicits robust immune responses through in situ dendritic cell (DC) maturation2012
- Author(s)
  Shimizu K, Mizuno T, Shinga J, Asakura M, Kakimi K, Sato Y, Fujii S
- Organizer
  12th International Symposium on Dendritic Cells
- Place of Presentation
  Daegu, Korea
- Data Source
  KAKENHI-PROJECT-23380186
[Presentation] 生体内樹状細胞を標的とした人工アジュバントベクター細胞の開発2012
- Author(s)
  清水佳奈子, 朝倉三貴, 信賀順, 水野拓也, 垣見和宏, 佐藤悠輔, 藤井眞一郎*
- Organizer
  第16回日本がん免疫学会総会
- Place of Presentation
  (札幌)シンポジスト
- Data Source
  KAKENHI-PROJECT-23380186
[Presentation] 新しく樹立したイヌリンパ腫細胞株のin vitroおよびin vivoにおける性状解析2012
- Author(s)
  梅城沙織、江馬康夫、鈴木綾一、久保正仁,林俊春、岡村泰彦、山崎淳平、辻本元、谷健二、平岡博子、奥田優、水野拓也
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学(盛岡市
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] イヌのTT-1に対する抗体の特異性の解析2012
- Author(s)
  酒井治、中谷亮太、梅城沙織、酒井洋樹、久保正仁、森本将弘、林俊春、平岡博子、奥田優、水野拓
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学(盛岡市)
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] Discovering the oncolytic potential of reovirus in veterinary medicine : reovirus-induced cell death in canine lymphoma and mast cell tumor cell lines2012
- Author(s)
  Hwang Chung Chew、梅城沙織、中川貴之、下田宙、望月雅美、前田健、平岡博子、奥田優、水野拓也
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学(盛岡市
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] 新しく樹立したイヌリンパ腫細胞株のin vitroおよびin vivoにおける性状解析2012
- Author(s)
  梅城沙織、江馬康夫、鈴木綾一、久保正仁, 林俊春、岡村泰彦、山崎淳平、辻本元、谷健二、平岡博子、奥田優、水野拓也
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学(盛岡市)
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-24380170
[Presentation] イヌのリンパ腫において過剰発現する遺伝子の解析2012
- Author(s)
  柳瀬拓磨、梅城沙織、酒井治、平岡博子、藤原亜紀、辻本元、奥田優、水野拓也
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学(盛岡市
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] イヌのWT-1に対する抗体の特異性の解析2012
- Author(s)
  酒井治、中谷亮太、梅城沙織、酒井洋樹、久保正仁、森本将弘、林俊春、平岡博子、奥田優、水野拓也
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学（盛岡市）
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] Discovering the oncolytic potential of reovirus in veterinary medicine : reovirus-induced cell death in canine lymphoma and mast cell tumor cell lines2012
- Author(s)
  Hwang Chung Chew、梅城沙織、中川貴之、下田宙、望月雅美、前田健、平岡博子、奥田優、水野拓也
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学（盛岡市）
- Data Source
  KAKENHI-PROJECT-24658268
[Presentation] サイクリン依存性キナーゼ(Cdk)阻害剤を用いたイヌのリンパ腫腫瘍細胞株の増殖抑制のメカニズムの解析2011
- Author(s)
  江馬康夫、梅城沙織、奥田優、水野拓也
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  大阪府立大学
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-21688022
[Presentation] cDNAマクロアレイを用いたイヌのリンパ腫に特異的に発現する遺伝子の解析2011
- Author(s)
  柳瀬拓磨、江馬康夫、梅城沙織、馬場健司、平岡博子、奥田優、水野拓也
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  大阪府立大学
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-21688022
[Presentation] Development of anti-tumor artificial adjuvant vector cells linking innate and adaptive immunity2011
- Author(s)
  Shimizu K, Sugahara H, Shinga J, Kakimi K, Mizuno T, Asakura M, Fujii S
- Organizer
  第15回日本癌免疫学会総会
- Place of Presentation
  (吹田)ワークショップ
- Data Source
  KAKENHI-PROJECT-23380186
[Presentation] Pセレクチン糖蛋白リガンド1の過剰発現による付着系細胞の浮遊現象機構の解明2011
- Author(s)
  梅城沙織、鈴木綾一、江馬康夫、西村順裕、奥田優、水野拓也
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  大阪府立大学
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-21688022
[Presentation] Characterization of anti-canine P-selectin ligand-1 antibody(2011 Proceedings of Veterinary Cancer Society 11/ 5 Embassy Suites Albuquerque Hotel & Spa2011
- Author(s)
  Saori Umeki, Yasuo Ema, Masayuki Shimojoima, Hiroko Hiraoka, Masaru Okuda, Takuya Mizuno
- Organizer
  Albuquerque
- Place of Presentation
  New Mexico
- Data Source
  KAKENHI-PROJECT-21688022
[Presentation] イヌにおける癌関連遺伝子WT-1の発現の解析2011
- Author(s)
  酒井治、栗尾雄三、梅城沙織、酒井洋樹、久保正仁、森本将弘、林俊春、平岡博子、奥田優、水野拓也
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  大阪府立大学
- Year and Date
  2011-09-20
- Data Source
  KAKENHI-PROJECT-21688022
[Presentation] Characterization of anti-canine P-selectin ligand-1 antibody2011
- Author(s)
  Saori Umeki, Yasuo Ema, Masayuki Shimojoima, Hiroko Hiraoka, Masaru Okuda, Takuya Mizuno
- Organizer
  2011 Proceedings of Veterinary Cancer Society
- Place of Presentation
  Albuquerque, New Mexico
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-21688022
[Presentation] Pセレクチン糖蛋白リガンド1の過剰発現による付着系細胞の浮遊現象の解析2010
- Author(s)
  梅城沙織、鈴木〓一、江馬康夫、西村順裕、奥田優、水野拓也
- Organizer
  第150回日本獣医学会学術集会
- Place of Presentation
  帯広畜産大学
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-21688022
[Presentation] 犬のリンパ腫における転写因子Foxp3の発現の解析2008
- Author(s)
  水野拓也、鈴木稜一、奥田優
- Organizer
  第146回日本獣医学会
- Place of Presentation
  宮崎
- Year and Date
  2008-08-24
- Data Source
  KAKENHI-PROJECT-19780232
[Presentation] 犬のリンパ腫における転写因子Foxp 3の発現の解析2008
- Author(s)
  水野拓也ほか
- Organizer
  第146回日本獣医学会
- Place of Presentation
  宮崎
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19780232
[Presentation] Reovirus infection dysregulates the Ras signaling pathway in canine mast cell tumor cells
- Author(s)
  Hwang CC, Coffery M, Noguchi S, Okuda M, Mizuno T.
- Organizer
  23rd Biennial Congress of the EUROPEAN ASSOCIATION FOR CANCER RESEARCH
- Place of Presentation
  Munich（ドイツ）
- Year and Date
  2014-07-05 – 2014-07-08
- Data Source
  KAKENHI-PROJECT-24380170

1. SHIMIZU Kanako (20391980)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. MAEDA Sadatoshi (50377694)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. TSUJIMOTO Hajime (60163804)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. NAKAGAWA Takayuki (40447363)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. Nakamura Michihiro (10314858)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 櫻井優 (00747967)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 伊賀瀬雅也 (70847110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. 太田啓介 (00258401)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 中村純奈 (10821944)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. 望月ちひろ (80831875)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. 塩浜康雄 (40715017)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. HONDO Eiichi (30271745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. MAEDA Ken (90284273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. TAKEMATSU Yoko (30335773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. KAMISHINA Hiroaki (50506847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NISHIFUJI Koji (20365422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. FUJII Shin-ichiro (10392094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
18. KUBO Masato (40593439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
19. Miyazawa Takayuki (80282705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. 富張瑞樹 (00552754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 野口俊助 (10701295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 今村拓也 (90390682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 中川草 (70510014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. 渋谷周作 (20534473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 板本和仁 (50379921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 坂井祐介 (60615722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 加藤茂樹 (90790767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KIM HYUNGJIN (80711457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 臼井達哉 (80727652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 恒富亮一 (10420514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 呰上大吾 (80453934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 川野竜司 (90401702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. TSOHIHIRO Tsukui

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 林俊春

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 垣見和宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mizuno Takuya 水野 拓也

MIZUNO Takuya 水野 拓也

Research Projects

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Co-Researchers

犬口腔内メラノーマの腫瘍免疫シグネチャの層別化に基づく複合治療法の開発と実践Principal Investigator

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リバーストランスレーショナル研究による犬メラノーマに対する最適な免疫療法の確立Principal Investigator

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Development and demonstration of a universal antibody drug actively working against canine malignancies.Principal Investigator

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Establishment of a novel CAR-T therapy for canine melanomaPrincipal Investigator

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Development of the combined immune-modulatory therapies for canine cancerPrincipal Investigator

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Identification of targeted antigen for the treatment of canine T cell lymphoma by using multiple immunization.Principal Investigator

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Analysis of the genes expressed in canine lymphoma using in vitro and in vivo methodology.Principal Investigator

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Is "steric hindrance effect" the possible new concept for tumor metastasis mechanism?Principal Investigator

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Mizuno Takuya 水野拓也

MIZUNO Takuya 水野拓也