YOSHIKAWA Kiwamu 吉川究

… Alternative Names

吉川究ヨシカワキワム

芳川究ヨシカワキワム

Less

Researcher Number	90400481
Other IDs
Affiliation (Current)	2025: 秋田大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2020 – 2022: 秋田大学, 医学系研究科, 助教 2015: 秋田大学, 大学院医学研究科, 助教 2015: 秋田大学, 大学院医学系研究科, 助教 2011 – 2015: 秋田大学, 医学(系)研究科(研究院), 助教 2013: 秋田大学, 大学院医学系研究科, 助教 2007: 秋田大学, 医学部, 助教 2005 – 2006: Akita University School of Medicine, Research Associate, 医学部, 助手
Review Section/Research Field	Except Principal Investigator Integrated Nutrition Science / General anatomy (including Histology/Embryology) / Pediatric surgery / Basic Section 48010:Anatomy-related / Ecology/Environment
Keywords	Except Principal Investigator 細胞外マトリックス / 肝臓星細胞 / コラーゲン / ヤツメウナギ / ビタミンA / 肝臓 / 胆汁 / 星細胞 / 微細形態 / 胆道閉鎖症 … More / ジアシルグリセロール / 介在ニューロン / プルキンエ細胞 / 海馬 / 滑面小胞体 / マウス肺 / ウェスタンブロット法 / 細胞膜 / スプライスバリアント / 中枢神経 / 免疫細胞化学染色 / 免疫組織化学染色 / 特異抗体 / ジアシルグリセロールキナーゼ / ホスホリパーゼD / Signal transport / Collagen / Gene expression / Extracellular matrix / Cell / 遺伝子発現制御 / マトリックスメタロプロテアーゼ / 細胞内シグナル伝達 / インテグリン / PCR-differential display / I型コラーゲン / シグナル伝達 / 発現制御 / 細胞 / タンパク質 / 酵素 / 小腸 / NASH / 肝線維化 / ビタミンE / ビタミンＥ / トコール / 肝線維症 / アノイキス誘導 / MMP / アノイキス / 肝硬変 / スピッツベルゲン / 北極圏生物 / セシウム137 / セシウム134 / セシウム１３７ / セシウム１３４ / 地衣類 / スピッツベルゲン島 / スバールバル群島 / 北極圏動物 / 放射能汚染 / 炎症性腸疾患 / 免疫監視 / 肝臓の星細胞 / ビタミンA貯蔵細胞 / 粘膜固有層 / 消化管 / TUNEL法 / レチノイド / アポトーシス / 線維化 / 高速液クロ / 毛細胆管 / コレステロール / 胆汁酸 / ヤツメナギ Less

Morphological and functional analyses of the tissue distribution and subcellular localization of the metabolizing/producing enzymes for lipid second messengers.
- Principal Investigator
  
  Hozumi Yasukazu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Akita University
Modulation of enzymatic activities of vitamin A-metabolizing enzymes by cellular retinol-binding proteins
- Principal Investigator
  
  Mezaki Yoshihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Jikei University School of Medicine
  Akita University
Radiocontamination of fauna and flora of the Arctic
- Principal Investigator
  
  Senoo Haruki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Ecology/Environment
- Research Institution
  Akita University
Elucidation of the mechanism of anoikis induction by vitamin E-analogous compound and application to the pharmacotherapy for hepatic cirrhosis.
- Principal Investigator
  
  Yamaguchi Noriko
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Akita University
Structure and function of the vitamin A-storing cells in the digestive tract
- Principal Investigator
  
  SENOO Haruki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Akita University
胆道閉鎖症治療への応用を目指した胆汁成分の新しい処理機構の解明
- Principal Investigator
  
  妹尾春樹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatric surgery
- Research Institution
  Akita University
Gene regulation by 3-D structure of extracellular matrix : a model for hepatic stellate cells
- Principal Investigator
  
  IRIE Toshiaki, 佐藤充
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Hokkaido National College of Technology
  Akita University
胆汁成分の新規処理機構の解明-胆道閉鎖症治療への応用を目指して-
- Principal Investigator
  
  SENOO Haruki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatric surgery
- Research Institution
  Akita University

All 2015 2014 2013 2012 2006 Other

All Journal Article Presentation

[Journal Article] Massive bowel resection upregulates intestinal expressions of cellular retinol-binding protein II and apolipoprotein A-IV mRNAs and alters intestinal vitamin A status in rats.2015
- Author(s)
  Hebiguchi T., Mezaki Y., Morii M., Watanabe R., Yoshikawa K., Miura M., Imai K., Senoo H., Yoshino H.
- Journal Title
  
  Int. J. Mol. Med.
  
  Volume: 35(3) Issue: 3 Pages: 724-730
- DOI
  10.3892/ijmm.2015.2066
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25504001
[Journal Article] The role of retinoic acid receptors in activated hepatic stellate cells2013
- Author(s)
  Mezaki Y., Morii M., Hebiguchi T., Yoshikawa K., Yamaguchi N, Yoshino H., Senoo H
- Journal Title
  
  Med. Hypotheses
  
  Volume: 81(2) Issue: 2 Pages: 222-224
- DOI
  10.1016/j.mehy.2013.04.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592623, KAKENHI-PROJECT-24614003, KAKENHI-PROJECT-25504001
[Journal Article] Differential Increases in the Expression of Intermediate Filament Proteins and Concomitant Morphological Changes of Transdifferentiating Rat Hepatic Stellate Cells Observed <i>In Vitro</i>2013
- Author(s)
  Mezaki Y., Morii M., Hebiguchi T., Yoshikawa K., Yamaguchi N, Miura M., Imai K., Yoshino H., Senoo H
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 46 Issue: 5 Pages: 137-143
- DOI
  10.1267/ahc.13007
- NAID
  130003381866
- ISSN
  0044-5991, 1347-5800
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592623, KAKENHI-PROJECT-24614003, KAKENHI-PROJECT-25504001
[Journal Article] Characterization of a cellular retinol binding protein from lamprey, Lethenteron japonicum. CBP Part B2012
- Author(s)
  Mezaki, M., Morii, M., Yoshikawa, K., Yamaguchi, N., Miura, M. , Imai, K., Yoshino, H., Senoo, H
- Journal Title
  
  Biochemistry & Molecular Biology
  
  Volume: 161 Pages: 233-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590228
[Journal Article] ヤツメウナギ細胞質レチノール結合タンパク質のキャラクタリゼーション2012
- Author(s)
  目崎喜弘, 森井真也子, 吉川究, 山口典子, 三浦光隆, 今井克幸, 吉野裕顕, 妹尾春樹
- Journal Title
  
  ビタミン
  
  Volume: 86 Pages: 313-315
- NAID
  10031086293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590228
[Journal Article] Distribution of retinylester-storing stellate cells in the arrowtooth halibut, Atheresthes evermanni2006
- Author(s)
  Yoshikawa, K
- Journal Title
  
  Comp.Biochem.Physiol.Part A 145
  
  Pages: 280-286
- Data Source
  KAKENHI-PROJECT-18659519
[Presentation] レシチン：レチノールアシルトランスフェラーゼ酵素活性に対する細胞質レチノール結合タンパク質IIの影響2015
- Author(s)
  目崎喜弘，蛇口　琢，森井真也子，吉川　究，三浦光隆，今井克幸，吉野裕顕，妹尾春樹
- Organizer
  第120回日本解剖学会総会・全国学術集会　第92回日本生理学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-22
- Data Source
  KAKENHI-PROJECT-25504001
[Presentation] ビタミンＥ類縁化合物、トコールは肝臓星細胞に対して線維形成コラーゲン合成を低下させ、アノイキスを誘導する2015
- Author(s)
  山口典子、目崎喜弘，三浦光隆，稲垣豊，吉川究
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24614003
[Presentation] 肝臓星細胞のビタミンＡ脂質滴形成におけるPerilipin 2/ADRP、Perilipin 3/TIP47の関与2015
- Author(s)
  吉川究、目崎喜弘、森居真也子、三浦光隆、今井克幸、山口典子
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24614003
[Presentation] 細胞質レチノール結合タンパク質共存下におけるビタミンAエステル化酵素活性の測定2014
- Author(s)
  目崎喜弘，蛇口　琢，森井真也子，吉川　究，三浦光隆，今井克幸，吉野裕顕，妹尾春樹
- Organizer
  日本ビタミン学会第66回大会
- Place of Presentation
  姫路
- Year and Date
  2014-06-13
- Data Source
  KAKENHI-PROJECT-25504001
[Presentation] 活性化肝臓星細胞における中間径フィラメントの役割2014
- Author(s)
  目崎喜弘，森井真也子，蛇口琢，吉川　究，山口典子，三浦光隆，今井克幸，吉野裕顕，妹尾春樹
- Organizer
  第119回日本解剖学会総会・全国学術集会
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-25504001
[Presentation] 肝臓星細胞（ビタミンA貯蔵細胞）の活性化における中間径フィラメントの発現量と局在の変化2013
- Author(s)
  目崎喜弘、森井真也子、蛇口琢、吉川究、山口典子、三浦光隆、今井克幸、吉野裕顕、妹尾春樹
- Organizer
  日本ビタミン学会第65回大会
- Place of Presentation
  一橋大学
- Data Source
  KAKENHI-PROJECT-24614003
[Presentation] Differential increases in the expression of intermediate filament proteins in transdifferentiating rat hepatic stellate cells.2013
- Author(s)
  Y Mezaki, M Morii, T Hebiguchi, K Yoshikawa, N Yamaguchi, M Miura, K Imai, H Yoshino, H Senoo
- Organizer
  17th International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Osaka International Convention Center
- Data Source
  KAKENHI-PROJECT-24614003
[Presentation] 肝臓星細胞（ビタミンA貯蔵細胞）の活性化における中間径フィラメントの発現量と局在の変化2013
- Author(s)
  目崎喜弘，森井真也子，蛇口　琢，吉川　究，山口典子，三浦光隆，今井克幸，吉野裕顕，妹尾春樹
- Organizer
  日本ビタミン学会第65回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25504001
[Presentation] Involvement of perilipin2/ADRP and perilipin3/TIP47 in the formation of vitamin A-storing lipid droplets in hepatic stellate cells.2013
- Author(s)
  K Yoshikawa, Y Mezaki, T Hebiguchi, M Miura, K Imai, N Yamaguchi
- Organizer
  17th International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Osaka International Convention Center
- Data Source
  KAKENHI-PROJECT-24614003
[Presentation] Differential increases in the expression of intermediate filament proteins in transdifferentiating rat hepatic stellate cells2013
- Author(s)
  Mezaki Y., Morii M., Hebiguchi T., Yoshikawa K., Yamaguchi N., Miura M., Imai K., Yoshino H. Senoo H.
- Organizer
  17th International Symposium on Cells of Hepatic Sinusoid
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-25504001
[Presentation] ビタミンE類縁化合物、トコールの肝臓星細胞に対するアノイキス誘導2013
- Author(s)
  山口典子、目崎喜弘、三浦光隆、稲垣豊、吉川究
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24614003
[Presentation] 肝臓星細胞のビタミンA脂質滴形成におけるPerilipin 3/TIP47の関与2013
- Author(s)
  吉川究、目崎喜弘、森井真也子、蛇口琢、三浦光隆、今井克幸、山口典子
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウインクあいち
- Data Source
  KAKENHI-PROJECT-24614003
[Presentation] Induction of Anoikis by Tocol in Rat Hepatic Stellate cells2012
- Author(s)
  Noriko Yamaguchi, Yoshihiro Mezaki, Mitsutaka Miura, Mayako Morii, Katsuyuki Imai, Yutaka Inagaki, Kiwamu Yoshikawa
- Organizer
  The 35th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24614003
[Presentation] The metabolism of cholesterol after bile duct degeneration in lamprey2012
- Author(s)
  Morii, M., Mezaki, Y., Yamaguchi, N., Yoshikawa, K., Miura, M., Imai, K., Hebiguchi, T., Watanabe, R., Yoshino, H., Senoo, H
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-23590228
[Presentation] 分子レベルで考察するヤツメウナギのビタミンA貯蔵2012
- Author(s)
  目崎喜弘、森井真也子、吉川究、山口典子、三浦光隆、今井克幸、吉野裕顕、妹尾春樹
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-23590228
[Presentation] 細胞内レチノール結合タンパク質の分子進化とビタミンA貯蔵2012
- Author(s)
  目崎喜弘、蛇口琢、森井真也子、吉川究、山口典子、三浦光隆、今井克幸、吉野裕顕、妹尾春樹
- Organizer
  第3回分子生命研究会(旧秋田県電気泳動研究会)
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-23590228
[Presentation] 肝臓星細胞のビタミンＡ脂質滴
- Author(s)
  吉川究、目崎喜弘、蛇口琢、三浦光隆、今井克幸、山口典子
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良県新公会堂
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24614003
[Presentation] 肝臓星細胞のビタミンＡ脂質滴形成におけるADRP、TIP47の関与
- Author(s)
  吉川究、目崎喜弘、蛇口琢、三浦光隆、今井克幸、山口典子
- Organizer
  第120回日本解剖学会総会・全国学術集会（第92回日本生理学会大会との合同大会）
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-03-21 – 2015-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-24614003
[Presentation] ビタミンE類縁化合物、トコールの肝臓星細胞に対するアノイキス誘導はMMP合成の促進を伴う
- Author(s)
  山口典子、目崎喜弘、三浦光隆、稲垣豊、吉川究
- Organizer
  第8回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24614003

1. SENOO Haruki (90171355)

# of Collaborated Projects: 6 results

# of Collaborated Products: 11 results
2. MEZAKI Yoshihiro (40431621)

# of Collaborated Projects: 5 results

# of Collaborated Products: 22 results
3. IRIE Toshiaki (90231167)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. Yamaguchi Noriko (90251553)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
5. 加藤哲夫 (20004963)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 萱場広之 (70224706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 吉野裕顕 (90182807)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 佐藤充 (60226008)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 東伸好 (60361218)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. Hozumi Yasukazu (00372334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 伊藤正毅 (40126389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 佐藤岳哉 (10312696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 桃井隆 (40143507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MAYAKO Morii

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 蛇口琢

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHIKAWA Kiwamu 吉川 究

吉川 究 ヨシカワ キワム

芳川 究 ヨシカワ キワム

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Massive bowel resection upregulates intestinal expressions of cellular retinol-binding protein II and apolipoprotein A-IV mRNAs and alters intestinal vitamin A status in rats.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The role of retinoic acid receptors in activated hepatic stellate cells2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential Increases in the Expression of Intermediate Filament Proteins and Concomitant Morphological Changes of Transdifferentiating Rat Hepatic Stellate Cells Observed <i>In Vitro</i>2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Characterization of a cellular retinol binding protein from lamprey, Lethenteron japonicum. CBP Part B2012

Author(s)

Journal Title

Data Source

[Journal Article] ヤツメウナギ細胞質レチノール結合タンパク質のキャラクタリゼーション2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Distribution of retinylester-storing stellate cells in the arrowtooth halibut, Atheresthes evermanni2006

Author(s)

Journal Title

Data Source

[Presentation] レシチン：レチノールアシルトランスフェラーゼ酵素活性に対する細胞質レチノール結合タンパク質IIの影響2015

Author(s)

Organizer

YOSHIKAWA Kiwamu 吉川究

吉川究ヨシカワキワム

芳川究ヨシカワキワム