UEDA Kazuhiro 上田和弘

… Alternative Names

上田和弘ウエダカズヒロ

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Researcher Number	90420520
Other IDs
Affiliation (Current)	2025: 鹿児島大学, 医歯学域医学系, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 鹿児島大学, 医歯学域医学系, 教授 2023: 鹿児島大学, 医歯学総合研究科, 教授 2020 – 2022: 鹿児島大学, 医歯学総合研究科, 特任准教授 2012 – 2020: 山口大学, 医学部附属病院, 講師 2014: 山口大学, 医学部, 講師 … More 2011: 山口大学, 大学院・医学系研究科, 講師 2010: 山口大学, 医学部附属病院, 助教 2007: Yamaguchi University, 医学部・附属病院, 助教 2006: 山口大学, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 55040:Respiratory surgery-related / Thoracic surgery / Respiratory surgery Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Clinical oncology / Respiratory surgery / Radiation science / Thoracic surgery / Digestive surgery
Keywords	Principal Investigator 肺癌 / 肺切除 / 代償性肺成長 / 生体力学 / 原発性肺癌 / 腫瘍内間質細胞 / 正常肺 / 間質細胞 / stromal cell / 接着分子 … More / 細胞外マトリックス / 癌関連間質細胞 / MCP-1 / 肺機能 / 癌進展 / 肺再生 / AMD3100 / pulmonary resection / bone marrow cell / compensatory lung growth / 骨髄由来細胞 / 血管内皮前駆細胞 / 血管再生 / 癌化学療法 / CXCR4 / Chemotherapy / Endotheial progenitor cell … More Except Principal Investigator 肺癌 / 非小細胞肺癌 / BHLHE41/DEC2 / バイオマーカー / 肺気腫 / 肺癌進行中・後期 / 肺癌進行早期 / オートファジー細胞死 / 線維芽細胞 / スキップ転移 / 胸膜リンパ流 / リンパ管 / cGAS/STING pathway / 癌免疫応答 / in vitro / IRF3 / 免役組織学的評価 / STING signaling pathway / 樹状細胞 / マクロファージ / 肺癌所属リンパ節 / 呼吸器外科臨床 / 上皮内癌 / DEC2 / 癌抑制遺伝子 / BHLHE41/DEC2発現制御機構 / オートファジー / RNA修飾酵素 / RNA修飾 / 抗癌剤抵抗性 / 肺気腫合併肺癌 / 癌関連線維芽細胞 / volumetric measurement / すりガラス様高吸収域 / 多変量解析 / 肺結節の容積測定法 / EGFR遺伝子変異 / 高分解能CT / 肺腺癌 / 国際情報交換 / 国内多施設共同研究 / 第II相試験 / 術前導入化学放射線療法 / Ｓｕｐｅｒｉｏｒ　Ｓｕｌｃｕｓ　Ｔｕｍｏｒ / 手術 / 術前導入療法 / Superior sulcus tumor / プロテオミクス / 分子標的 / 悪性胸膜中皮腫 / 免疫染色 / MMP2 / MMP / 肺腫瘍 / MT1-MMP / MMP-2 / 癌血管新生 / 癌細胞増殖 / 血管内皮前駆細胞 / 手術侵襲 Less

間質性肺炎合併肺癌における線維芽細胞の可逆的形質変化に着目した網羅的解析
- Principal Investigator
  
  上村豪
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kagoshima University
メカノバイオロジーの視点からの代償性肺再構築の分子機構の解明と肺再生療法の開発Principal Investigator
- Principal Investigator
  
  上田和弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kagoshima University
肺癌悪性化進行過程を考慮したオートファジー細胞死の機構解明
- Principal Investigator
  
  永田俊行
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kagoshima University
STING伝達経路の肺癌進行における役割―免疫療法中心に集学的治療の確立に向けて
- Principal Investigator
  
  青木雅也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kagoshima University
胸膜リンパ流によるスキップ転移機序の解明：解剖・分子生物学から呼吸器外科へ
- Principal Investigator
  
  武田亜矢
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kagoshima University
Multilateral analysis of the regulatory mechanism of transcription factor BHLHE41/DEC2 expression and its clinical significance in lung cancer.
- Principal Investigator
  
  NAGATA Toshiyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kagoshima University
  Shizuoka Cancer Center Research Institute
Search for target molecules based on comprehensive analysis of functional gain in mechanisms of cancer-associated stromal cellsPrincipal Investigator
- Principal Investigator
  
  Ueda Kazuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kagoshima University
Elucidation of the role of RNA-modifying enzymes in anticancer drug-resistant non-small cell lung cancer
- Principal Investigator
  
  Tanaka Toshiki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Yamaguchi University
Mechanisms of enhanced tumor growth during compensatory lung growth after major lung resectionPrincipal Investigator
- Principal Investigator
  
  UEDA Kazuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Yamaguchi University
The role of high-resolution CT in the individual chemotherapheutic treatment for lung cancer
- Principal Investigator
  
  TANAKA Nobuyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Yamaguchi University
Mechanism identification and Developing a novel method for therapy against lung cancer invasion via cancer-associated fibroblasts in pulmonary emphysema
- Principal Investigator
  
  HAYASHI Masataro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Yamaguchi University
Trial for identification of targeting molecules in malignant pleural mesothelioma by proteomics
- Principal Investigator
  
  KURAMITSU Yasuhiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Yamaguchi University
A phase II study of induction cisplatin plus TS-1 with concurrent radiotherapy (66Gy) followed by surgical resection in patients with superior sulcus tumor
- Principal Investigator
  
  TSUSHIMA Yukio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Clinical oncology
- Research Institution
  Juntendo University
The mobilization and recruitment of endothelial progenitor cells contribute to acceleration of tumor growth after surgery
- Principal Investigator
  
  ENOKI Tadahiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
Investigation about the mechanism that lung cancer growth is accelerated in emphysematous lungs
- Principal Investigator
  
  HAYASHI Masataro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Yamaguchi University
Significant role of bone marrow-derived cells in compensatory regenerative lung growthPrincipal Investigator
- Principal Investigator
  
  UEDA Kazuhiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Yamaguchi University
癌再発・進展における血管内皮前駆細胞の役割Principal Investigator
- Principal Investigator
  
  上田和弘
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Yamaguchi University

All 2024 2023 2022 2021 2017 2016 2015 2013 2012 2011 2006

All Journal Article Presentation

[Journal Article] Localization of macrophages and dendritic cells in human thoracic lymph nodes: An immunohistochemical study using surgically obtained specimens.2023
- Author(s)
  Aoki M, Jin ZW*, Ueda K, Kamimura G, Takeda-Harada A, Murakami G, Sato M.
- Journal Title
  
  J Anat.
  
  Volume: 243 Issue: 3 Pages: 504-516
- DOI
  10.1111/joa.13870
- Data Source
  KAKENHI-PROJECT-22K08980
[Journal Article] Clinical Significance of Nodal DCsign Expression in Non-small-cell Lung Cancer Patients2023
- Author(s)
  Aoki M*, Kamimura GO, Morizono S, Tokunaga T, Umehara T, Harada-Takeda A, Maeda K, Nagata T, Ueda K, Tabata K, Murakami G, Sato M.
- Journal Title
  
  Anticancer Res.
  
  Volume: 43 Issue: 7 Pages: 3003-3013
- DOI
  10.21873/anticanres.16471
- Data Source
  KAKENHI-PROJECT-22K08980
[Journal Article] Human lymph node degeneration in the thoracic region: A morphometric and immunohistochemical analysis using surgically obtained specimens.2022
- Author(s)
  Jin ZW*, Aoki M (#Co-first author), Ueda K, Kamimura G, Takeda-Harada A, Murakami G, Sato M.
- Journal Title
  
  Front Physiol.
  
  Volume: 13 Pages: 990801-990801
- DOI
  10.3389/fphys.2022.990801
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08980
[Journal Article] BHLHE41/DEC2 Expression Induces Autophagic Cell Death in Lung Cancer Cells and Is Associated with Favorable Prognosis for Patients with Lung Adenocarcinoma.2021
- Author(s)
  Toshiyuki Nagata, Kentaro Minami, Masatatsu Yamamoto, Tsubasa Hiraki, Masashi Idogawa, Katsumi Fujimoto, Shun Kageyama, Kazuhiro Tabata, Kohichi Kawahara, Kazuhiro Ueda, Ryuji Ikeda, Yukio Kato, Masaaki Komatsu, Akihide Tanimoto, Tatsuhiko Furukawa, Masami Sato
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 22 Issue: 21 Pages: 11509-11509
- DOI
  10.3390/ijms222111509
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-18K09638, KAKENHI-PROJECT-19K08372, KAKENHI-PROJECT-20K08209, KAKENHI-PROJECT-20K09181, KAKENHI-PROJECT-21K06691, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-21K07129, KAKENHI-PROJECT-19K22566
[Journal Article] Size-capacity mismatch in the lung: a novel predictor for complications after lung cancer surgery2017
- Author(s)
  Murakami J, Ueda K, Hayashi M, Kobayashi T, Kunihiro Y, Hamano K
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 209 Pages: 131-138
- DOI
  10.1016/j.jss.2016.08.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10259
[Journal Article] Enhanced tumor growth in the remaining lung after major lung resection2016
- Author(s)
  Fumiho Sano, Kazuhiro Ueda, Junichi Murakami, Masataro Hayashi, Arata Nishimoto, Kimikazu Hamano
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 202 Issue: 1 Pages: 1-7
- DOI
  10.1016/j.jss.2015.12.012
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10259
[Journal Article] Pulmonary emphysema and tumor microenvironment in primary lung cancer2016
- Author(s)
  Murakami J, Ueda K, Sano F, Hayashi M, Nishimoto A, Hamano K
- Journal Title
  
  Journal of surgical research
  
  Volume: 200 Pages: 690-697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462177
[Journal Article] Significant role of bone marrow-derived cells in compensatory regenerative lung growth2013
- Author(s)
  Suga A, Ueda K, Takemoto Y, Nishimoto A, Hosoyama T, Li TS, Hamano K
- Journal Title
  
  Journal of Surgical Research
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591569
[Journal Article] Operative injury accelerates tumor growth by inducing mobilization and recruitment of bone marrow-derived stem cells2011
- Author(s)
  Yoshihiro Takemoto, Tao-Sheng Li, Masayuki Kubo, Mako Ohshima, Kazuhiro Ueda, Eijirou Harada, Tadahiko Enoki, Mariko Okamoto, Yoichi Mizukami, Tomoaki Murata, Kimikazu Hamano
- Journal Title
  
  SURGERY
  
  Volume: 149巻 Pages: 792-800
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591456
[Journal Article] Computed tomography-diagnosed emphysema, not airway obstruction, is associated with the prognostic outcome of early-stage lung cancer.2006
- Author(s)
  Ueda K, et al.
- Journal Title
  
  Clinical Cancer Research. 12
  
  Pages: 6730-6736
- Data Source
  KAKENHI-PROJECT-18790994
[Journal Article] Relationship among genetic alteration, DNA content, and clinicopathological features in primary lung adenocarcinoma.2006
- Author(s)
  Ueda K, et al.
- Journal Title
  
  Cancer Genomics ＆ Proteomics 3
  
  Pages: 265-270
- Data Source
  KAKENHI-PROJECT-18790994
[Presentation] 肺癌所属リンパ節におけるDCsignの臨床病理学的重要性～樹状細胞とマクロファージとの関連性について2024
- Author(s)
  青木雅也、岩元嘉志、森園翔一朗、徳永拓也、梅原　正、武田亜矢、上村　豪、永田俊行、上田和弘
- Organizer
  第41回日本呼吸器外科学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08980
[Presentation] Preoperative quantitative assessment of lung morphology is useful in the risk assessment of lung cancer surgery2022
- Author(s)
  上田和弘
- Organizer
  日本胸部外科学会
- Data Source
  KAKENHI-PROJECT-20K09182
[Presentation] マウス肺全摘後の残存肺での癌進展の促進効果2015
- Author(s)
  佐野　史歩・上田　和弘・村上　順一・林　雅太郎・濱野　公一
- Organizer
  第56回日本肺癌学会総会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-15K10259
[Presentation] 腫瘍間質のMMP-9高発現は肺癌の臨床病理学的悪性度に関与する; 特に肺気腫に発生した肺癌との関連について2015
- Author(s)
  村上順一、上田和弘、佐野史歩、林雅太郎、濱野公一
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-25462177
[Presentation] Pulmonary emphysema as a tumor-friendly microenvironment: Role of the MT1-MMP/MMP-2 axis2013
- Author(s)
  Junichi Murakami, Kazuhiro Ueda, Arata Nishimoto, Masataro Hayashi, and Kimikazu Hamano
- Organizer
  American Association for Cancer research (AACR) ANNUAL MEETING 2013
- Place of Presentation
  WashingtonD.C.(USA)
- Data Source
  KAKENHI-PROJECT-22591568
[Presentation] 肺気腫は肺腫瘍増大に好適な微小環境である:MT1-MMP/MMP-2 axis の関与2013
- Author(s)
  村上順一、林雅太郎、上田和弘、李桃生、濱野公一
- Organizer
  第113回日本外科学会定期学術集会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-22591568
[Presentation] 代償性肺成長における骨髄由来細胞の役割2013
- Author(s)
  菅淳、上田和弘、林雅太郎、濱野公一
- Organizer
  第113回日本外科学会定期学術集会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2013-04-11
- Data Source
  KAKENHI-PROJECT-22591569
[Presentation] 肺気腫は肺腫瘍増大に好適な微小環境である:MT1-MMP/MMP-2 axis の関与2012
- Author(s)
  村上順一、林雅太郎、上田和弘、濱野公一
- Organizer
  第65回日本胸部外科学会定期学術大会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-22591568
[Presentation] Tumor growth is accelerated in emphysematous lungs via the MT1-MMP/MMP-2 axis2012
- Author(s)
  村上順一、西本新、上田和弘
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(札幌)
- Data Source
  KAKENHI-PROJECT-22591568

1. 上村豪 (80927187)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
2. 青木雅也 (50624996)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
3. 武田亜矢 (80794700)

# of Collaborated Projects: 4 results

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4. TANAKA Toshiki (50457305)

# of Collaborated Projects: 3 results

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5. 佐藤雅美 (30250830)

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6. HAYASHI Masataro (00554057)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. LI Taosheng (50379997)

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# of Collaborated Products: 1 results
8. NISHIMOTO Arata (90396325)

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9. NAGATA Toshiyuki (70611763)

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10. 前田光喜 (70795674)

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# of Collaborated Products: 1 results
11. ENOKI Tadahiko (80311819)

# of Collaborated Projects: 1 results

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12. TAKEMOTO Yoshihiro (50622213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. KURAMITSU Yasuhiro (50281811)

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14. TSUSHIMA Yukio (20560684)

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15. SUZUKI Kenji (10415523)

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16. TAKAMOCHI Kazuya (30397369)

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17. OH Shiaki (50306958)

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18. OKADA Morihito (70446045)

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19. IKEDA Norihiko (70246205)

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20. TANAKA Fumihiro (10283673)

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21. OKUMURA Sakae (40465935)

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22. NAKAMURA Haruhiko (80183523)

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23. SUZUKI Hiroyuki (30322340)

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24. NAKAMURA Hiroshige (30252852)

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25. IWATA Hisashi (90303495)

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26. TSUBOI Masahiro (90297309)

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27. SUGIO Kenji (70235927)

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28. MANIWA Yoshimasa (50362778)

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29. DOKI Yoshinori (90303221)

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30. MAEHARA Yoshihiko (80165662)

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31. UENO Tsuyoshi (80509456)

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32. TAKENOYAMA Mitsuhiro (10309966)

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33. URAMOTO Hidetaka (90389445)

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34. YOSHINO Ichiro (40281547)

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35. TANAKA Nobuyuki (90294636)

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36. HOSHII Yoshinobu (00263773)

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37. MATSUNAGA Naofumi (40157334)

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38. KIDO Shoji (90314814)

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39. 上野耕司 (30736070)

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40. 狩集弘太 (20648050)

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41. 横枕直哉 (00418857)

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42. 梅原正 (20837794)

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43. 石原由香 (60770419)

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44. 森園翔一朗 (90918913)

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45. NAGASIMA Takuya

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46. SHIONO Satoshi

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47. MATSUURA Motoki

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48. OKUMURA Norihito

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49. HORIO Hirotoshi

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50. INASAWA Keitaro

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# of Collaborated Products: 0 results
51. FUNAI Kazuhito

# of Collaborated Projects: 1 results

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52. ITOU Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. 南謙太朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

UEDA Kazuhiro 上田 和弘

上田 和弘 ウエダ カズヒロ

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メカノバイオロジーの視点からの代償性肺再構築の分子機構の解明と肺再生療法の開発Principal Investigator

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Search for target molecules based on comprehensive analysis of functional gain in mechanisms of cancer-associated stromal cellsPrincipal Investigator

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Mechanisms of enhanced tumor growth during compensatory lung growth after major lung resectionPrincipal Investigator

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UEDA Kazuhiro 上田和弘

上田和弘ウエダカズヒロ