Matsuoka Kenichi 松岡賢市

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MATSUOKA Ken-ichi 松岡賢市

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Researcher Number	90432640
Other IDs
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 岡山大学, 医歯薬学域, 准教授 2017 – 2020: 岡山大学, 医歯薬学総合研究科, 准教授 2017: 岡山大学, 大学院医歯薬学総合研究科, 准教授 2015 – 2016: 岡山大学, 大学病院, 講師 2012 – 2014: 岡山大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology
Keywords	Principal Investigator 移植片対宿主病 / 免疫寛容 / 制御性T細胞 / 同種造血幹細胞移植 / 造血幹細胞移植 / GVHD / 慢性GVHD / 同種造血細胞移植 / 造血幹細胞移植学 / 血液内科学 … More / 橋渡し研究 / 肺GVHD / 閉塞性細気管支炎 / 移植後シクロフォスファミド法 / B細胞 / 移植後シクロフォスファミド / 慢性移植片対宿主病 / 移植対宿主病 / 移植片対白血病効果 / NKT細胞 / 移植後シクロフォスファミド療法 / 細胞療法 / 移植免疫 / インターロイキン２ … More Except Principal Investigator 造血幹細胞移植 / シングルセル解析 / 空間マルチオミックス / 同種造血幹細胞移植 / 免疫寛容 / 移植片対宿主病 / 制御性T細胞 Less

Elucidation of Post-Transplant Immune Reconstitution Mechanisms through Spatial Single-Cell Multiomics Analysis
- Principal Investigator
  
  前田嘉信
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Okayama University
Development of precision medicine based on a comprehensive understanding of the local inflammatory environment in chronic pulmonary GVHDPrincipal Investigator
- Principal Investigator
  
  松岡賢市
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Okayama University
Development of the prediction marker and the preemptive therapy for chronic GVHD based on abnormal B cell homeostasis during the acute phase of allogeneic HSCTPrincipal Investigator
- Principal Investigator
  
  Matsuoka Ken-ichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Okayama University
Development of a novel algorithm for immune regulation that enables the active Treg amplification soon after HSCTPrincipal Investigator
- Principal Investigator
  
  Matsuoka Ken-ichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Okayama University
Low-dose IL-2 therapy to maintain Treg homeostasis under the use of calcineurin inhibitor
- Principal Investigator
  
  Tanimoto Mitsune
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Okayama University
Low-dose IL-2 combined with PD-1 blockade separates GVHD and GVL effect.Principal Investigator
- Principal Investigator
  
  Ken-ichi Matsuoka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Okayama University
Restoration of Treg homeostasis with Low-dose IL-2 administiration for patients with refractory chronic GVHDPrincipal Investigator
- Principal Investigator
  
  MATSUOKA Ken-ichi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Okayama University

All 2024 2023 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book Patent

[Book] 血液内科「慢性GVHDに対する新規治療法」2014
- Author(s)
  松岡賢市
- Total Pages
  8
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] がん分子標的療法「免疫チェックポイント分子を標的とした治療の展開」2014
- Author(s)
  松岡賢市
- Total Pages
  3
- Publisher
  メデイカルレビュー社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] 血液内科「慢性GVHDの新規治療法」2013
- Author(s)
  松岡賢市, 他
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] 血液フロンティア2013
- Author(s)
  松岡　賢市
- Total Pages
  8
- Publisher
  医薬ジャーナル
- Data Source
  KAKENHI-PROJECT-24790975
[Book] GVHD(移植片対宿主病)の基礎と臨床2013
- Author(s)
  松岡賢市, 他
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] 血液フロンティア「間葉系幹細胞など細胞療法の新展開」2013
- Author(s)
  松岡賢市
- Total Pages
  9
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] 臨床免疫・アレルギー科「造血幹細胞移植後の免疫トレランスとレギュラトリー T 細胞2013
- Author(s)
  松岡賢市
- Total Pages
  7
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] みんながよく分かるGVHD2013
- Author(s)
  松岡　賢市
- Total Pages
  8
- Publisher
  医薬ジャーナル
- Data Source
  KAKENHI-PROJECT-24790975
[Book] 臨床免疫・アレルギー科「造血幹細胞移植後の免疫トレランスとレギュラトリーT細胞」2013
- Author(s)
  松岡賢市, 他
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] 血液フロンティア「間葉系幹細胞など細胞療法の新展開」2013
- Author(s)
  松岡賢市, 他
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] GVHD（移植片対宿主病）の基礎と臨床2013
- Author(s)
  松岡賢市、共著
- Total Pages
  9
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] 血液内科2012
- Author(s)
  松岡　賢市
- Total Pages
  8
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] Trends in Hematological Malignancies「慢性GVHDにおけるTreg恒常性の破綻とその回復」2012
- Author(s)
  松岡賢市, 他
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] 血液内科「インターロイキン2によるGVHD治療と制御性T細胞」2012
- Author(s)
  松岡賢市, 他
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24790975
[Book] Trends in Hematological Malignancies2012
- Author(s)
  松岡　賢市
- Total Pages
  7
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-24790975
[Journal Article] Novel insights into GVHD and immune reconstitution after allogeneic hematopoietic cell transplantation2023
- Author(s)
  Takanori Teshima, Jaap Jan Boelens, Ken-ichi Matsuoka
- Journal Title
  
  Blood Cell Therapy
  
  Volume: 2 Issue: 2 Pages: 1-6
- DOI
  10.31547/bct-2022-023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08753, KAKENHI-PROJECT-23K07814
[Journal Article] Hematopoietic stem cell-derived Tregs are essential for maintaining favorable B cell lymphopoiesis following posttransplant cyclophosphamide2023
- Author(s)
  Sumii Y, Kondo T, Ikegawa S, Fukumi T, Iwamoto M, Nishimura MF, Sugiura H, Sando Y, Nakamura M, Meguri Y, Matsushita T, Tanimine N, Kimura M, Asada N, Ennishi D, Maeda Y, Matsuoka KI.
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 8 Pages: 1-21
- DOI
  10.1172/jci.insight.162180
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08753
[Journal Article] GVHDの予防と治療の新たな展開2021
- Author(s)
  松岡賢市
- Journal Title
  
  臨床血液
  
  Volume: 62 Pages: 602-609
- NAID
  130008061920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08753
[Journal Article] Graft-versus-host disease: current understanding of immune pathogenesis and clinical treatment2021
- Author(s)
  松岡賢市
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 62 Issue: 8 Pages: 1281-1287
- DOI
  10.11406/rinketsu.62.1281
- NAID
  130008085943
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08753
[Journal Article] Post-transplantation cyclophosphamide restores early B-cell lymphogenesis that suppresses subsequent chronic graft-versus-host disease2021
- Author(s)
  Iwamoto M, Ikegawa S, Kondo T, Meguri Y, Nakamura M, Sando Y, Sugiura H, Sumii Y, Asada N, Ennishi D, Nishimori H, Fujii K, Fujii N, Shibakura M, Maeda Y, Matsuoka KI.
- Journal Title
  
  Bone Marrow Transplant
  
  Volume: 56 Issue: 4 Pages: 956-959
- DOI
  10.1038/s41409-020-01100-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08753
[Journal Article] PTCy ameliorates GVHD by restoring regulatory and effector T-cell homeostasis in recipients with PD-1 blockade.2019
- Author(s)
  Ikegawa S, Meguri Y, Kondo T, Sugiura H, Sando Y, Nakamura M, Iwamoto M, Maeda Y, Matsuoka KI.
- Journal Title
  
  Blood Adv.
  
  Volume: 3 Issue: 23 Pages: 4081-4094
- DOI
  10.1182/bloodadvances.2019000134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09954
[Journal Article] iNKT細胞と同種造血幹細胞移植2019
- Author(s)
  中村真、松岡賢市
- Journal Title
  
  造血細胞移植学会雑誌
  
  Volume: 8 巻 1 号 Pages: 28-35
- NAID
  130007580085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09954
[Journal Article] PD-1 modulates regulatory T-cell homeostasis during low-dose interleukin-2 therapy.2017
- Author(s)
  Asano T, Meguri Y, Yoshioka T, Kishi Y, Iwamoto M, Nakamura M, Sando Y, Yagita H, Koreth J, Kim HT, Alyea EP, Armand P, Cutler CS, Ho VT, Antin JH, Soiffer RJ, Maeda Y, Tanimoto M, Ritz J, Matsuoka KI.
- Journal Title
  
  Blood
  
  Volume: 129 Issue: 15 Pages: 2186-2197
- DOI
  10.1182/blood-2016-09-741629
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461449, KAKENHI-PROJECT-15K09504
[Journal Article] Treatment of thrombotic microangiopathy after hematopoietic stem cell transplantation with recombinant human soluble thrombomodulin2016
- Author(s)
  Fujiwara H, Maeda Y, Sando Y, Nakamura M, Tani K, Ishikawa T, Nishimori H, Matsuoka K, Fujii N, Kondo E, Tanimoto M.
- Journal Title
  
  Transfusion
  
  Volume: 56 Issue: 4 Pages: 886-92
- DOI
  10.1111/trf.13437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09504, KAKENHI-PROJECT-26461449
[Journal Article] Vigorous inflammatory responses in noninfectious pulmonary complication induced by donor lymphocyte infusion.2016
- Author(s)
  Nishie M, Fujii N, Mimura Y, Asano T, Mimura-Kimura Y, Aoe K, Aoe M, Nakashima H, Fujiwara H, Nishimori H, Matsuoka K, Kondo E, Maeda Y, Tanimoto M.
- Journal Title
  
  Transfusion
  
  Volume: 56 Issue: 1 Pages: 231-6
- DOI
  10.1111/trf.13283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09504, KAKENHI-PROJECT-26461449
[Journal Article] Pretransplantation Anti-CCR4 Antibody Mogamulizumab Against Adult T-Cell Leukemia/Lymphoma Is Associated With Significantly Increased Risks of Severe and Corticosteroid-Refractory Graft-Versus-Host Disease, Nonrelapse Mortality, and Overall Mortality.2016
- Author(s)
  Fuji S, Inoue Y, Utsunomiya A, Moriuchi Y, Uchimaru K, Choi I, Otsuka E, Henzan H, Kato K, Tomoyose T, Yamamoto H, Kurosawa S, Matsuoka K, Yamaguchi T, Fukuda T.
- Journal Title
  
  J Clin Oncol
  
  Volume: 34(28) Issue: 28 Pages: 3426-33
- DOI
  10.1200/jco.2016.67.8250
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09504, KAKENHI-PROJECT-16K09875
[Journal Article] Anti-IL-12/23 p40 antibody attenuates experimental chronic graft-versus-host disease via suppression of IFN-γ/IL-17-producing cells.2015
- Author(s)
  Okamoto S, Fujiwara H et al.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 194 Issue: 3 Pages: 13571363-13571363
- DOI
  10.4049/jimmunol.1400973
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591424, KAKENHI-PROJECT-25221305, KAKENHI-PROJECT-26461449
[Journal Article] リンハ腫治療におけるPD-1阻害2014
- Author(s)
  松岡賢市
- Journal Title
  
  腫瘍内科
  
  Volume: 14(5) Pages: 455-462
- Data Source
  KAKENHI-PROJECT-26461449
[Journal Article] Mammalian target of rapamycin inhibitors permit regulatory T cell reconstitution and inhibit experimental chronic graft-versus-host disease.2014
- Author(s)
  Sugiyama H, Maeda Y, Nishimori H, Yamasuji Y, Matsuoka K, Fjii N, Kondo E, Shinagawa K, Takeuchi K, Teshima T, and Tanimoto M
- Journal Title
  
  Biol Blood Marrow Transplant.
  
  Volume: 20 Issue: 2 Pages: 183-91
- DOI
  10.1016/j.bbmt.2013.11.018
- NAID
  120005469526
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790975, KAKENHI-PROJECT-25293217, KAKENHI-PROJECT-25670443
[Journal Article] Increased mitochondrial apoptotic priming of human regulatory T cells after allogeneic hematopoietic stem cell transplantation.2014
- Author(s)
  Murase K, Kim HT, Bascug OR, Kawano Y, Ryan J, Matsuoka K, Davids MS, Koreth J, Ho VT, Cutler C, Armand P, Alyea EP, Blazar BR, Antin JH, Soiffer RJ, Letai A, Ritz J.
- Journal Title
  
  Haematologica
  
  Volume: 99(9) Issue: 9 Pages: 1499-508
- DOI
  10.3324/haematol.2014.104166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461449
[Journal Article] Exploring regulatory T cell-based therapy for refractory graft-versus-host disease2014
- Author(s)
  Ken-ichi Matsuoka
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 55(6) Pages: 670-81
- NAID
  130004501867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461449
[Journal Article] Exploring regulatory T cell-based therapy for refractory graft-versus-host disease2014
- Author(s)
  松岡賢市
- Journal Title
  
  臨床血液
  
  Volume: 55 Pages: 1-1
- NAID
  130004501867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790975
[Journal Article] Exploring regulatory T cell-based therapy for refractory graft-versus-host disease2014
- Author(s)
  Matsuoka K
- Journal Title
  
  Jpn J Clin Hematol
  
  Volume: (in press)
- NAID
  130004501867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790975
[Journal Article] Bronchiolitis obliterans with allogeneic hematopoietic cell transplantation: a 10-year experience of the Okayama BMT Group.2014
- Author(s)
  Fujii N, Nakase K, Asakura S, Matsuo K, Nawa Y, Sunami K, Nishimori H, Matsuoka KI, Kondo E, Maeda Y, Shinagawa K, Hara M, Tanimoto M.
- Journal Title
  
  Int J Hematol.
  
  Volume: 99 Issue: 5 Pages: 1556-1556
- DOI
  10.1007/s12185-014-1556-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790975
[Journal Article] Programmed Death-1 Pathway in Host Tissues Ameliorates Th17/Th1-Mediated Experimental Chronic Graft-versus-Host Disease2014
- Author(s)
  Hideaki Fujiwara, Yoshinobu Maeda et al.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 193 Issue: 5 Pages: 25652573-25652573
- DOI
  10.4049/jimmunol.1400954
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591424, KAKENHI-PROJECT-26253086, KAKENHI-PROJECT-26461449
[Journal Article] 急性リンパ性白血病に対するCAR細胞療法の新たな展開2014
- Author(s)
  松岡賢市
- Journal Title
  
  血液内科
  
  Volume: 69(5) Pages: 652-657
- Data Source
  KAKENHI-PROJECT-26461449
[Journal Article] Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease2013
- Author(s)
  Matsuoka K, Koreth J, Kim HT, Bascug G, McDonough S, Kawano Y, Murase K, Cutler C, Ho VT, Alyea EP, Armand P, Blazar BR, Antin JH, Soiffer RJ, Ritz J.
- Journal Title
  
  Science Translational Medicine
  
  Volume: 5 Issue: 179 Pages: 179-190
- DOI
  10.1126/scitranslmed.3005265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790975
[Journal Article] CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells.2013
- Author(s)
  Naito M, Hainz U, Burkhardt UE, Fu B, Ahove D, Stevenson KE, Rajasagi M, Zhu B, Alonso A, Witten E, Matsuoka K, Neuberg D, Wu CJ, Freeman GJ
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: 62 Issue: 2 Pages: 347-57
- DOI
  10.1007/s00262-012-1331-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790975
[Journal Article] Induction of antitumor immunity ex vivo using dendritic cells transduced with fowl pox vector expressing MUC1, CEA, and a triad of costimulatory molecules (rF-PANVAC)2012
- Author(s)
  Vasir B, Zarwan C, Ahmad R, Crawford K, Rajabi H, Matsuoka K, Rosenblatt J, Wu Z, Mills H, Kufe D, Avigan D
- Journal Title
  
  J Immunotherapy
  
  Volume: 35(7) Issue: 7 Pages: 555-69
- DOI
  10.1097/cji.0b013e31826a73de
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790975
[Patent] ハプロ移植増強剤2017
- Inventor(s)
  松岡賢市、中村真、前田嘉信、石井保之、秋元秀俊、川口絵美
- Industrial Property Rights Holder
  松岡賢市、中村真、前田嘉信、石井保之、秋元秀俊、川口絵美
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K09954
[Presentation] GVHDの基礎病態と治療標的2024
- Author(s)
  松岡賢市
- Organizer
  日本造血・免疫細胞療法学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K07814
[Presentation] Pretransplant short-term exposure of donor graft cells to ITK selective inhibitor prevents acute GVHD in mouse BMT model2020
- Author(s)
  Takumi Kondo, Yasuhisa Sando, Yuichi Sumii, Shuntaro Ikegawa, Hiroyuki Sugiura, Makoto Nakamura, Miki Iwamoto, Yusuke Meguri, Yoshinobu Maeda, and Ken-ichi Matsuoka
- Organizer
  Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09954
[Presentation] In Vivo Modulation of Regulatory and Effector T cell Homeostasis for Maximization of GVL Effect in Allogeneic HSCT2019
- Author(s)
  Ken-ichi Matsuoka
- Organizer
  日本血液学会国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09954
[Presentation] PTCy Promote Naïve B Cell Recovery coordinated with Early Treg Expansion: Possible mechanism for preventing chronic GVHD2019
- Author(s)
  岩本美紀, 松岡賢市, 廻勇輔, 池川俊太郎, 杉浦弘幸, 三道康永, 中村真, 近藤匠, 浅野豪, 前田嘉信
- Organizer
  日本血液疾患免疫療法学会
- Data Source
  KAKENHI-PROJECT-17K09954
[Presentation] PTCy Ameliorates PD-1-/- donor-induced GVHD by Restoring Regulatory and Effector T cell Homeostasis2019
- Author(s)
  Shuntaro Ikegawa, Ken-ichi Matsuoka, Yusuke Meguri, Takumi Kondo, Hiroyuki Sugiura, Yasuhisa Sando, Makoto Nakamura, Miki Iwamoto, and Yoshinobu Maeda
- Organizer
  日本血液学会
- Data Source
  KAKENHI-PROJECT-17K09954
[Presentation] NKT and Tolerance, Revisited; Liposomal α-GalCer as an Immune Modulator after Reduced-Dose PTCy2018
- Author(s)
  Ken-ichi Matsuoka
- Organizer
  JSHCT annual meeting
- Invited
- Data Source
  KAKENHI-PROJECT-17K09954
[Presentation] Liposomal Alpha-Galactosylceramide Ameliorates GVHD with Remaining Intensified GVL Gained by Dose-Reduction of Posttransplant Cyclophosphamaide after Haploidentical BMT2017
- Author(s)
  Makoto Nakamura, Ken-ichi Matsuoka, Yusuke Meguri, Shuntaro Ikegawa, Hiroyuki Sugiura, Yasuhisa Sando, Miki Iwamoto, Takeru Asano, Yasuyuki Ishii and Yoshinobu Maeda
- Organizer
  ASH annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09954
[Presentation] Role of Regulatory T cells in Hematopoietic Stem Cell Transplantation2015
- Author(s)
  Ken-ichi Matsuoka
- Organizer
  台湾血液学会
- Place of Presentation
  台北市
- Year and Date
  2015-04-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] 造血幹細胞移植に関わる免疫学～免疫システムを安全に入れ替えたい～2015
- Author(s)
  松岡賢市
- Organizer
  第４回岡山フローサイトメトリー研究会
- Place of Presentation
  岡山県岡山市
- Year and Date
  2015-02-21
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] ～造血幹細胞移植を可視化する～　移植後免疫再構築の基本的枠組みについて2015
- Author(s)
  松岡賢市
- Organizer
  日本血液学会中国四国地方会教育セミナー
- Place of Presentation
  鳥取県鳥取市
- Year and Date
  2015-03-13
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] PD-1 signaling has a critical role in maintaining Regulatory T Cell Homeostasis; Implication for Treg depletion therapy by PD-1 Blockade2015
- Author(s)
  Takeru Asano, Ken-ichi Matsuoka
- Organizer
  American Society of Hematology
- Place of Presentation
  オーランド
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] Rapid Assessment of Low-dose IL-2 Administration on Foxp3+ Regulatory T cell Homeostasis2014
- Author(s)
  廻勇輔、松岡賢市、浅野豪、吉岡尚徳、岸佑里子、谷本光音
- Organizer
  日本血液学会国際シンポジウム
- Place of Presentation
  静岡県浜松市
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] 造血幹細胞移植における制御性T細胞の役割2014
- Author(s)
  松岡賢市
- Organizer
  血液科学セミナー
- Place of Presentation
  東京都
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] 低用量インターロイキン-2療法は慢性移植片対宿主病患者において制御性T細胞のホメオスタシスを回復させる2014
- Author(s)
  松岡賢市
- Organizer
  第２回血液学アカデミー
- Place of Presentation
  京都府京都市
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] ハプロ移植後DLIによるHelios(+)制御性T細胞の増幅は急性GVHD発症を抑制する2014
- Author(s)
  吉岡尚徳、松岡賢市、廻勇輔、淺野豪、黒井大雅、石川立則、佐伯恭昌、長谷川詠子、山本宜和、谷勝真、塩手康弘、藤井伸治、近藤英生、前田嘉信、品川克至、谷本光音
- Organizer
  日本造血幹細胞移植学会
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Rapid Assessment of Low-dose IL-2 Administration on Foxp3+ Regulatory T cell Homeostasis2014
- Author(s)
  廻勇輔, 松岡賢市, 他
- Organizer
  日本血液学会国際シンポジウム
- Place of Presentation
  浜松
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] 制御性T細胞をめぐるヒトとマウスの「あいだ」2014
- Author(s)
  松岡賢市
- Organizer
  第18回血液三都物語若手の会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2014-07-19
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] 造血幹細胞移植と制御性T細胞2013
- Author(s)
  松岡賢市
- Organizer
  日本バイオセラピー学会学術集会総会
- Place of Presentation
  岩手県盛岡市
- Invited
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Exploring regulatory T cell-based therapy for refractory graft-versus-host disease2013
- Author(s)
  松岡賢市
- Organizer
  日本血液学会
- Place of Presentation
  北海道札幌市
- Invited
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] ハプロ移植後DLIによるHelios(+)制御性T細胞の増幅は急性GVHD 発症を抑制する2013
- Author(s)
  吉岡尚徳, 松岡賢市, 他
- Organizer
  日本造血幹細胞移植学会総会
- Place of Presentation
  沖縄
- Year and Date
  2013-03-17
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Chronic inflammatory demyelinating polyradiculoneuropathy following low-dose donor lymphocyte infusion after haplo-identical hematopoietic stem cell transplantation2013
- Author(s)
  Taiga Kuroi, Ken-ichi Matsuoka, Takanori Yoshioka, Yusuke Meguri, Kyosuke Saeki, Eiko Hasegawa, Takeru Asano, Nobuharu Fujii, Eisei Kondo, Yoshinobu Maeda, Katsuji Shinagawa, Shoko Deguchi, Kentaro Deguchi, Makoto Takeuchi and Mitsune Tanimoto
- Organizer
  日本血液学会国際シンポジウム
- Place of Presentation
  愛媛県松山市
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Host Tissue PD-1 Pathway Contribute To Murine Chronic Graft-Versus-Host Disease Via Th1+Th17+ Cells2013
- Author(s)
  Fujiwara H, Matsuoka K, 他
- Organizer
  米国血液学会総会
- Place of Presentation
  ニューオーリンズ
- Year and Date
  2013-12-09
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Low-Dose IL-2 Induces Bcl2 Expression and Resistance To Apoptosis In CD4 Regulatory T Cells2013
- Author(s)
  Murase K, Matsuoka K, 他
- Organizer
  米国血液学会総会
- Place of Presentation
  ニューオーリンズ
- Year and Date
  2013-12-09
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Chronic inflammatory demyelinating polyradiculoneuropathy following low-dose donor lymphocyte infusion after haplo-identical hematopoietic stem cell transplantation2013
- Author(s)
  黒井大雅, 松岡賢市, 他
- Organizer
  日本血液学会国際シンポジウム
- Place of Presentation
  松山
- Year and Date
  2013-05-25
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Low-Dose IL-2 Induces Bcl2 Expression and Resistance To Apoptosis In CD4 Regulatory T Cells2013
- Author(s)
  Kazuyuki Murase, Yutaka Kawano, Jeremy Ryan, Ken-ichi Matsuoka, Gregory Bascug, Sean McDonough, Robert W Smith, Kristen Cowens, Suzan Lazo-Kallanian, John Daley, John Koreth, Robert J. Soiffer, Anthony Letai, Jerome Ritz
- Organizer
  Annual meeting of American Society of Hematology
- Place of Presentation
  米国ニューオーリンズ
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Host Tissue PD-1 Pathway Contribute To Murine Chronic Graft-Versus-Host Disease Via Th1+Th17+ Cells2013
- Author(s)
  Hideaki Fujiwara, Yoshinobu Maeda, Koichiro Kobayashi, Hisakazu Nishimori, Ken-ichi Matsuoka, Miyuki Azuma, Hideo Yagita, Lieping Chen, Mitsune Tanimoto
- Organizer
  Annual meeting of American Society of Hematology
- Place of Presentation
  米国ニューオーリンズ
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Exploring regulatory T cell-based therapy for refractory graft-versus-host disease2013
- Author(s)
  松岡賢市
- Organizer
  日本血液学会総会
- Place of Presentation
  札幌
- Year and Date
  2013-10-12
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Phenotypic and Functional characterizations of Recent Thymic Emigrant Regulatory T cells (RTE-Treg)2012
- Author(s)
  松岡賢市, 他
- Organizer
  日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2012-10-10
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] PD-1 regulates Treg homeostasis during low-dose IL-2 therapy in patients with chronic GVHD2012
- Author(s)
  松岡賢市, 他
- Organizer
  日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2012-10-10
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Phenotypic and Functional characterizations of Recent Thymic Emigrant Regulatory T cells (RTE-Treg)2012
- Author(s)
  Ken-ichi Matsuoka, Yusuke Meguri, Takanori Yoshioka, Jerome Ritz, Mitsune Taniomoto
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Differential Effects of TCR Stimulation and IL-2 On Apoptotic Pathways in CD4 Regulatory T Cells Compared to Conventional CD4 T Cells and CD8 T Cells2012
- Author(s)
  Murase K, Matsuoka K, 他
- Organizer
  米国血液学会総会
- Place of Presentation
  アトランタ
- Year and Date
  2012-12-10
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] PD-1 regulates Treg homeostasis during low-dose IL-2 therapy in patients with chronic GVHD2012
- Author(s)
  Ken-ichi Matsuoka, Yusuke Meguri, Takanori Yoshioka, Jerome Ritz, Mitsune Taniomoto
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Apoptotic Pathways of Human Regulatory T Cells in Chronic Graft Versus Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)2012
- Author(s)
  Fujiwara H, Matsuoka K, 他
- Organizer
  米国血液学会総会
- Place of Presentation
  アトランタ
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-24790975
[Presentation] Early homeostatic expansion of regulatory T cells after HSCT is susceptible to environmental factors
- Author(s)
  Takanori Yoshioka, Ken-ichi Matsuoka, Yusuke Meguri, Takeru Asano, Yuriko Kishi, Taiga Kuroi, Tatsunori Ishikawa, Kyosuke Saeki, Eiko Hasegawa, Yoshikazu Yamamoto, Katsuma Tani, Yasuhiro Shiote, Nobuharu Fujii, Eisei Kondo, Yoshinobu Maeda, Taro Masunari, Kumiko Kagawa, Koichi Nakase and Mitsune Tanimoto
- Organizer
  第76回日本血液学会総会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] Host immune status determines the effects of therapeutic Interleukin-2 administration: Enhancement of GVL or Induction of Tolerance?
- Author(s)
  Yusuke Meguri, Takeru Asano, Takanori Yoshioka, Haruka Izumi, Yuriko Kishi, Yoshinobu Maeda, Mitune Tanimoto, and Ken-ichi Matsuoka
- Organizer
  56th ASH Annual Meeting & Exposition
- Place of Presentation
  San Francisco
- Year and Date
  2014-12-08 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] Rapid Assessment of Low-dose IL-2 Administration on Foxp3+ Regulatory T cell Homeostasis
- Author(s)
  Yusuke Meguri, Ken-ichi Matsuoka, Takeru Asano, Takanori Yoshioka, Haruka Izumi Yuriko Kishi and Mitsune Tanimoto
- Organizer
  第76回日本血液学会総会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] Enhanced expression of PD-1 modulates CD4+Foxp3+ regulatory T cell homeostasis during low-dose IL-2 therapy in patients with chronic Graft-versus-Host disease
- Author(s)
  Takeru Asano, Haesook T. Kim, John Koreth, Robert Soiffer, Yusuke Meguri, Takanori Yoshioka, Hideo Yagita, Mitune Tanimoto, MD, PhD, Jerome Ritz, MD and Ken-ichi Matsuoka
- Organizer
  56th ASH Annual Meeting & Exposition
- Place of Presentation
  San Francisco
- Year and Date
  2014-12-08 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] Early Homeostatic Expansion of Regulatory T Cells with the Predominant Effector/Memory Phenotype May Stabilize Immune Recovery in the First Month after HSCT
- Author(s)
  Takanori Yoshioka, Yusuke Meguri, Takeru Asano, Taro Masunari, Kumiko Kagawa, Koichi Nakase, Yoshinobu Maeda, Mitsune Tanimoto, and Ken-ichi Matsuoka
- Organizer
  56th ASH Annual Meeting & Exposition
- Place of Presentation
  San Francisco
- Year and Date
  2014-12-08 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26461449
[Presentation] Rapid Assessment of Low-dose IL-2 Administration on Foxp3+ Regulatory T cell Homeostasis
- Author(s)
  Yusuke Meguri, Ken-ichi Matsuoka, Takeru Asano, Takanori Yoshioka, Haruka Izumi and Mitsune Tanimoto
- Organizer
  日本血液学会国際シンポジウム
- Place of Presentation
  静岡県浜松市
- Year and Date
  2014-05-25 – 2014-05-26
- Data Source
  KAKENHI-PROJECT-26461449

1. Tanimoto Mitsune (10240805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 前田嘉信 (60403474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 遠西大輔 (20825096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 淺田騰 (70803055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Matsuoka Kenichi 松岡 賢市

MATSUOKA Ken-ichi 松岡 賢市

Research Projects

Research Products

Co-Researchers

Elucidation of Post-Transplant Immune Reconstitution Mechanisms through Spatial Single-Cell Multiomics Analysis

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Development of precision medicine based on a comprehensive understanding of the local inflammatory environment in chronic pulmonary GVHDPrincipal Investigator

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Development of the prediction marker and the preemptive therapy for chronic GVHD based on abnormal B cell homeostasis during the acute phase of allogeneic HSCTPrincipal Investigator

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Development of a novel algorithm for immune regulation that enables the active Treg amplification soon after HSCTPrincipal Investigator

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Low-dose IL-2 therapy to maintain Treg homeostasis under the use of calcineurin inhibitor

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Low-dose IL-2 combined with PD-1 blockade separates GVHD and GVL effect.Principal Investigator

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Restoration of Treg homeostasis with Low-dose IL-2 administiration for patients with refractory chronic GVHDPrincipal Investigator

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[Book] 血液内科「慢性GVHDに対する新規治療法」2014

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[Book] がん分子標的療法「免疫チェックポイント分子を標的とした治療の展開」2014

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[Book] 血液内科「慢性GVHDの新規治療法」2013

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[Book] 血液フロンティア2013

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[Book] GVHD(移植片対宿主病)の基礎と臨床2013

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[Book] 血液フロンティア「間葉系幹細胞など細胞療法の新展開」2013

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[Book] 臨床免疫・アレルギー科「造血幹細胞移植後の免疫トレランスとレギュラトリー T 細胞2013

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Matsuoka Kenichi 松岡賢市

MATSUOKA Ken-ichi 松岡賢市