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Shimomura Masanori  下村 雅律

… Alternative Names

下村 雅律  シモムラ マサノリ

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Researcher Number 90433268
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-5099-9479
Affiliation (Current) 2025: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
Affiliation (based on the past Project Information) *help 2023 – 2025: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
2020 – 2022: 京都府立医科大学, 医学(系)研究科(研究院), 講師
2013 – 2018: 京都府立医科大学, 医学(系)研究科(研究院), 助教
2007: Kyoto Prefectural University of Medicine, 附属病院, 専攻医
Review Section/Research Field
Principal Investigator
Basic Section 55040:Respiratory surgery-related / Tumor diagnostics / Thoracic surgery
Except Principal Investigator
Basic Section 55040:Respiratory surgery-related / Medical sociology / Thoracic surgery
Keywords
Principal Investigator
パクリタキセル / CTOS / 大腸癌 / 転移性肺腫瘍 / STAS / 大腸癌肺転移 / 初代培養スフェロイド / パクリタキセル耐性関連タンパク / 薬効評価と予測 / パクリタキセル関連タンパク質 … More / FGNL1 / パクリタキセル耐性機序 / 抗がん剤耐性機序 / FIGNL1 / パクリタキセル固定化ビーズ / 抗がん剤耐性 / パクリタキセル耐性関連タンパク質 / プロテオーム解析 / パクリタキセル耐性 / mRNA発現 / 定量RT-PCR / 微小肺癌 / Tarsh遺伝子 / TARSH遺伝子 / 細胞老化 / mRNA / 肺癌 / TARSH … More
Except Principal Investigator
CTOS / 気腔内転移 / オルガノイド / STAS / 肺癌 / 遠隔教育 / オンライン授業 / 呼吸器外科 / オンライン学習 / 医学教育 / e-learning / 卒前教育 / 臨床実習 / 呼吸器外科学 / 医学部卒前教育 / 反転授業 / 自動追尾 / 3次元位置情報 / 胸腔鏡 Less
  • Research Projects

    (8 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (15 People)
  •  胸腺上皮性腫瘍オルガノイドを用いた分子標的薬テーラーメイド治療の開発Principal Investigator

    • Principal Investigator
      下村 雅律
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Spread through air spaces in pulmonary metastases from colorectal cancer analysed with cancer tissue-originated spheroidPrincipal Investigator

    • Principal Investigator
      下村 雅律
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Molecular mechanism of Spread Through Air Space in primary lung cancer

    • Principal Investigator
      井上 匡美
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Identification and mechanisms of paclitaxel resistance related protein in lung cancer cell linesPrincipal Investigator

    • Principal Investigator
      Shimomura Masanori
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Flipped classroom of thoracic surgery for undergraduate medical students

    • Principal Investigator
      Ito Kazuhiro
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical sociology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Paclitaxel resistance-associated proteins in lung cancer cell lines are detected by proteome analysesPrincipal Investigator

    • Principal Investigator
      Shimomura Masanori
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Cancer-associated transcriptional inactivation of NESH-TARSH in small-sized primary lung cancerPrincipal Investigator

    • Principal Investigator
      SHIMADA Junichi, 下村 雅律
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  胸腔鏡手術における手術部位の3次元位置情報の定量化と視野自動追尾装置に関する研究

    • Principal Investigator
      Ito Kazuhiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2023 2022 2021 2017 2013 2008 2007

All Journal Article Presentation

  • [Journal Article] Spread through air spaces is a powerful prognostic predictor in patients with completely resected pathological stage I lung adenocarcinoma2022

    • Author(s)
      Shimomura Masanori、Miyagawa-Hayashino Aya、Omatsu Ikoi、Asai Yumi、Ishihara Shunta、Okada Satoru、Konishi Eiichi、Teramukai Satoshi、Inoue Masayoshi
    • Journal Title

      Lung Cancer

      Volume: 174 Pages: 165-171

    • DOI

      10.1016/j.lungcan.2022.11.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K20326, KAKENHI-PROJECT-20K07411
  • [Presentation] Spread Through Air Spacesにおけるがん細胞塊極性の役割2023

    • Author(s)
      松浦吉晃、小沼邦重、下村雅律、岡田悟、内堀篤樹、井上匡美、井上正宏
    • Organizer
      第76回日本胸部外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-22K08982
  • [Presentation] Spread through air spaces陽性の腫瘍径2cm以下病理病期Ⅰ期肺腺癌切除例は肺転移再発が多く予後不良である2023

    • Author(s)
      下村雅律,岡田悟,石原駿太,古谷竜男,德田涼介,西井真知子,河村太陽,中川拓水,川西凜太郎,井上匡美
    • Organizer
      第76回日本胸部外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-23K20326
  • [Presentation] 浸潤径2cm以下病理病期I期肺腺癌切除例におけるSpread through air spaces陽性が術後再発に及ぼす影響2023

    • Author(s)
      下村雅律,岡田悟,石原駿太,古谷竜男,德田涼介,西井真知子,河村太陽,中川拓水,川西凜太郎,井上匡美
    • Organizer
      第64回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K20326
  • [Presentation] An in vitro model of Spread Through Air Spaces using organoids2022

    • Author(s)
      松浦吉晃、小沼邦重、下村雅律、内堀篤樹、井上匡美、井上正宏
    • Organizer
      第75回日本胸部外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-22K08982
  • [Presentation] オルガノイドを用いたがん気道内転移モデルによるSTASの病態検証2022

    • Author(s)
      松浦吉晃,小沼邦重,下村雅律,内堀篤樹,井上匡美,井上正宏
    • Organizer
      第63回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K20326
  • [Presentation] オルガノイドを用いたがん気道内転移モデルによるSTASの病態検証2022

    • Author(s)
      松浦吉晃、小沼邦重、下村雅律、内堀篤樹、井上匡美、井上正宏
    • Organizer
      第63回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K08982
  • [Presentation] An in vitro model of Spread Through Air Spaces using organoids2022

    • Author(s)
      松浦吉晃,小沼邦重,下村雅律,内堀篤樹,井上匡美,井上正宏
    • Organizer
      第75回日本胸部外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-23K20326
  • [Presentation] Spread Through Air Spacesは病理病期I期肺腺癌肺葉切除例における独立予後因子である2021

    • Author(s)
      下村雅律,常塚啓彰,石原駿太,谷口雄基,土橋亮太,垣淵大地,井上匡美
    • Organizer
      第74回日本胸部外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-23K20326
  • [Presentation] Continuous Education Using E-Learning System for Women Thoracic Surgeons on Maternity Leave2017

    • Author(s)
      Ito, K. Shimada, J. Nishimura, M. Shimomura, M. Kato, D. Inoue, M.
    • Organizer
      The 25 Annual Meeting of Asian Society for Cardiovascular and Thoracic Surgery
    • Place of Presentation
      ソウル、韓国
    • Year and Date
      2017-03-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08561
  • [Presentation] Paclitaxel resistance is associated with drug accumulation in intracellular compartments and paclitaxel-binding proteins in human lung cancer cell lines2013

    • Author(s)
      M. Shimomura, T. Yaoi, K. Itoh, D. Kato, J. Shimada, S Fushiki
    • Organizer
      European Cancer Congress 2013
    • Place of Presentation
      Amsterdam, Netherland
    • Data Source
      KAKENHI-PROJECT-25830104
  • [Presentation] Paclitaxel resistance is associated with drug accumulation in intracellular compartments and paclitaxel-binding proteins in human lung cancer cell lines2013

    • Author(s)
      M. Shimomura, T. Yaoi, K. Itoh, D. Kato, J. Shimada, S Fushiki
    • Organizer
      World Conference of Lung Cancer 2013
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-25830104
  • [Presentation] IA期の肺腺癌症例におけるTARSH mRNAの発現低下2008

    • Author(s)
      寺内邦彦、島田順一、若生武、伊藤和弘、柳田正志、下村雅律、常塚啓彰、矢追毅、丸山光生、伏木信次
    • Organizer
      第25回日本呼吸器外科学会総会
    • Place of Presentation
      宇都宮
    • Data Source
      KAKENHI-PROJECT-19591638
  • [Presentation] Cancer-associated transcriptional inactivation of TARSH in primary lung cancer2007

    • Author(s)
      寺内邦彦、島田順一、上川奈都子、伊藤和弘、柳田正志、下村雅律、常塚啓彰、矢追毅、丸山光生、伏木信次
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19591638
  • [Presentation] Loss of TARSH gene expression in primary lung adenocarcinoma2007

    • Author(s)
      K. Terauchi, J. Shimada, N. Uekawa, K. Ito, M. Yanada, M. Shimomura, H. Tsunezuka, T. Yaoi, M. Maruyama, S. Fushiki
    • Organizer
      12th Congress of the Asia Pacific Society of Respirology
    • Place of Presentation
      ゴールドコースト(オーストラリア)
    • Data Source
      KAKENHI-PROJECT-19591638
  • [Presentation] Marked decline of TARSH gene expression in primary lung cancer2007

    • Author(s)
      K. Terauchi, J. Shimada, N. Uekawa, K. Ito, M. Yanada, M. Shimomura, T. Yaoi, M. Maruyama, S. Fushiki
    • Organizer
      12th World Confbrence on Lung Cancer
    • Place of Presentation
      ソウル(韓国)
    • Data Source
      KAKENHI-PROJECT-19591638
  • [Presentation] I期非小細胞肺癌におけるTARSH遺伝子発現の検討2007

    • Author(s)
      寺内邦彦、島田順一、上川奈都子、伊藤和弘、柳田正志、下村雅律、矢追毅、丸山光生、伏木信次
    • Organizer
      第24回日本呼吸器外科学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19591638
  • [Presentation] TARSH遺伝子は非小細胞肺癌においてmRNA発現レベルの顕著な低下を示す2007

    • Author(s)
      寺内邦彦、島田順一、上川奈都子、伊藤和弘、柳田正志、下村雅律、矢追毅、丸山光生、伏木信次
    • Organizer
      第107回日本外科学会定期学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19591638
  • [Presentation] Marked decline of TARSH gene expression in primary lung cancer2007

    • Author(s)
      Terauchi K, Shimada J, Uekawa N, Ito K, Yanada M, Shimomura M, Yaoi T, Maruyama M, Fushiki S
    • Organizer
      12^<th> World Conference on Lung Cancer
    • Place of Presentation
      ソウル(韓国)
    • Data Source
      KAKENHI-PROJECT-19591638
  • [Presentation] Loss of TARSH gene expression in primary lung adenocarcinoma2007

    • Author(s)
      Terauchi K, Shimada J, Uekawa N, Ito K, Yanada M, Shimomura M, Tsunezuka H, Yaoi T, Maruyama M, Fushiki S
    • Organizer
      12^<th> Congress of the Asia Pacific Society of Respirology
    • Place of Presentation
      ゴールドコースト(オーストラリア)
    • Data Source
      KAKENHI-PROJECT-19591638
  • [Presentation] 細胞老化関連遺伝子TARSHの肺腺癌における発現の検討2007

    • Author(s)
      寺内邦彦、島田順一、上川奈都子、伊藤和弘、柳田正志、下村雅律、常塚啓彰、矢追毅、丸山光生、伏木信次
    • Organizer
      第48回日本肺癌学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19591638
  • 1.  SHIMADA Junichi (60315942)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 2.  KATO Daishiro (70315943)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  Ito Kazuhiro (30398367)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  井上 匡美 (10379232)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 5.  矢追 毅 (40311914)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  井上 正宏 (10342990)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 7.  TERAUCHI Kunihiko (10515290)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 8.  WAKOH Takeshi (10435878)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  MARUYAMA Mitsuo (00212225)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 10.  柳田 正志 (60453099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  西村 元宏 (00398372)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  石原 駿太 (60751279)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  伊東 恭子 (80243301)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  常塚 啓彰 (00453100)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  岡田 悟 (20572085)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results

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