Nishioku Tsuyoshi 西奥剛

… Alternative Names

NISHIOKU Tsuyoshi 西奥剛

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Researcher Number	90435115
Other IDs
Affiliation (Current)	2025: 長崎国際大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2024: 長崎国際大学, 薬学部, 教授 2014 – 2018: 長崎国際大学, 薬学部, 准教授 2009 – 2013: Fukuoka University, 薬学部, 助教
Review Section/Research Field	Principal Investigator General pharmacology / Basic Section 48030:Pharmacology-related / Applied pharmacology Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields
Keywords	Principal Investigator CD147 / 破骨細胞 / シクロフィリンA / 白質障害 / 関節リウマチ / カテプシンE / 薬理学 / ポドソーム / 脳血管性認知症 / オリゴデンドロサイト … More / 大脳白質 / 白質 / CypA / アデノシン / 免疫抑制 / 血液脳関門 / 白質脳症 / 生物学的製剤 … More Except Principal Investigator ナンセンス変異 / 未熟停止コドン / リードスルー / 化学修飾mRNA / 核酸医薬 Less

カテプシンEによるCD147のプロセッシングを介した関節リウマチの骨破壊機構Principal Investigator
- Principal Investigator
  
  西奥剛
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Nagasaki International University
Basic research into nucleic acid drugs that induce readthrough by chemically modifying the adenosine at the premature termination codon
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Nagasaki International University
Molecular mechanism of bone destruction in rheumatoid arthritis based on CD147Principal Investigator
- Principal Investigator
  
  NISHIOKU TSUYOSHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Nagasaki International University
Function of CD147 in white matter lesionsPrincipal Investigator
- Principal Investigator
  
  Nishioku Tsuyoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Nagasaki International University
  Fukuoka University
Function of cyclophilin A and CD147 in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  NISHIOKU Tsuyoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Fukuoka University
Monoclonal antibody against tumour necrosis factor alpha-associated leukoencephalopathy in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  NISHIOKU Tsuyoshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Fukuoka University

All 2018 2017 2016 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Berberine Induces Apoptotic Cell Death via Activation of Caspase-3 and -8 in HL-60 Human Leukemia Cells: Nuclear Localization and Structure?Activity Relationships2017
- Author(s)
  Okubo Shinya、Uto Takuhiro、Goto Aya、Tanaka Hiroyuki、Nishioku Tsuyoshi、Yamada Katsushi、Shoyama Yukihiro
- Journal Title
  
  The American Journal of Chinese Medicine
  
  Volume: 45 Issue: 07 Pages: 1497-1511
- DOI
  10.1142/s0192415x17500811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08567
[Journal Article] CD147 promotes the formation of functional osteoclasts through NFATc1 signalling.2016
- Author(s)
  Nishioku T, Terasawa M, Baba M, Yamauchi A, Kataoka Y
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 473(3) Issue: 2 Pages: 620-4
- DOI
  10.1016/j.bbrc.2016.03.147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460236, KAKENHI-PROJECT-25460349
[Journal Article] Paracellular Barrier and Tight Junction Protein Expression in the Immortalized Brain Endothelial Cell Lines bEND.3, bEND.5 and Mouse Brain Endothelial Cell 42013
- Author(s)
  Watanabe T, Dohgu S, Takata F, Nishioku T, Nakashima A, Futagami K, Yamauchi A, Kataoka Y.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Issue: 3 Pages: 492-495
- DOI
  10.1248/bpb.b12-00915
- NAID
  130003382085
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460349
[Journal Article] BMP4 is increased in the aortas of diabetic ApoE knockout mice andenhances uptake of oxidized low density lipoprotein into peritoneal macrophages.2013
- Author(s)
  Koga M, Yamauchi A, Kanaoka Y, Jige R, Tsukamoto A, Teshima N, Nishioku T,Kataoka Y.
- Journal Title
  
  J Inflamm
  
  Volume: 10(1) Issue: 1 Pages: 32-32
- DOI
  10.1186/1476-9255-10-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460236, KAKENHI-PROJECT-25460349, KAKENHI-PROJECT-25860134
[Journal Article] Atorvastatin stimulates neuroblastoma cells to induce neurite outgrowth by increasing cellular prion protein expression.2012
- Author(s)
  Watanabe T, Yasutaka Y, Nishioku T, Nakashima A, Futagami K, Yamauchi A, Kataoka Y.
- Journal Title
  
  Neurosci Lett
  
  Volume: 531(2) Issue: 2 Pages: 114-9
- DOI
  10.1016/j.neulet.2012.10.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790311
[Journal Article] Cyclophilin A secreted from fibroblast-like synoviocytes is involved in the induction of CD147 expression in macrophages of mice with collagen-induced arthritis.2012
- Author(s)
  Nishioku T, Dohgu S, Koga M, Machida T, Watanabe T, Miura T, Tsumagari K, Terasawa M, Yamauchi A, Kataoka Y.
- Journal Title
  
  J Inflamm (Lond)
  
  Volume: 9(1) Issue: 1 Pages: 44-44
- DOI
  10.1186/1476-9255-9-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790311
[Journal Article] Lipopolysaccharide-activated microglia lower P-glycoprotein function in brain microvascular endothelial cells.2012
- Author(s)
  Matsumoto J, Dohgu S, Takata F, Nishioku T, Sumi N, Machida T, Takahashi H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 524(1) Issue: 1 Pages: 45-8
- DOI
  10.1016/j.neulet.2012.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590163, KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790113, KAKENHI-PROJECT-23790311
[Journal Article] Autocrine and paracrine up-regulation of blood-brain barrier function by plasminogen activator inhibitor-1.2011
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Oda M, Harada E, Watanabe T, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Microvascular research.
  
  Volume: 81(1) Issue: 1 Pages: 103-7
- DOI
  10.1016/j.mvr.2010.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790311
[Journal Article] Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro2011
- Author(s)
  Takata F, Dohgu S, Matsumoto J, Takahashi H, Machida T, Wakigawa T, Harada E, Miyaji H, Koga M, Nishioku T, Yamauchi A, Kataoka Y.
- Journal Title
  
  J Neuroinflammation.
  
  Volume: 8 Issue: 1 Pages: 106-106
- DOI
  10.1186/1742-2094-8-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790113, KAKENHI-PROJECT-23790311
[Journal Article] A role for hypothalamic AMP-activated protein kinase in the mediation of hyperphagia and weight gain induced by chronic treatment with olanzapine in female rats.2011
- Author(s)
  Sejima E, Yamauchi A, Nishioku T, Koga M, Nakagama K, Dohgu S, Futagami K, Kataoka Y
- Journal Title
  
  Cell Mol Neurobiol.
  
  Volume: 31(7) Issue: 7 Pages: 985-9
- DOI
  10.1007/s10571-011-9663-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790311
[Journal Article] Partial hepatectomy aggravates cyclosporin A-induced neurotoxicity by lowering the function of the blood-brain barrier in mice.2011
- Author(s)
  Yamauchi A, Dohgu S, Takata F, Watanabe T, Nishioku T, Matsumoto J, Ohkubo Y, Shuto H, Kataoka Y.
- Journal Title
  
  Life Sciences
  
  Volume: 88(11-12) Pages: 529-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Partial hepatectomy aggravates cyclosporin A-induced neurotoxicity by lowering the function of the blood-brain barrier in mice.2011
- Author(s)
  Yamauchi A, Dohgu S, Takata F, Watanabe T, Nishioku T, Matsumoto J, Ohkubo Y, Shuto H, Kataoka Y.
- Journal Title
  
  Life Sci.
  
  Volume: 88(11-12) Issue: 11-12 Pages: 529-34
- DOI
  10.1016/j.lfs.2011.01.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590163, KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790311
[Journal Article] Potential role for S100A4 in the disruption of the blood-brain barrier incollagen-induced arthritic mice, an animal model of rheumatoid arthritis2011
- Author(s)
  Nishioku T, Furusho K, Tomita A, Ohishi H, Dohgu S, Shuto H, Yamauchi A, Kataoka Y
- Journal Title
  
  Neuroscience.
  
  Volume: 189 Pages: 286-92
- DOI
  10.1016/j.neuroscience.2011.05.044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590163, KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790311
[Journal Article] Partial hepatectomy aggravates cyclosporin A-induced neurotoxicity by lowering the function of the blood-brain barrier in mice.2011
- Author(s)
  Yamauchi A, Dohgu S, Takata F, Watanabe T, Nishioku T, Matsumoto J, Ohkubo Y, Shuto H, Kataoka Y.
- Journal Title
  
  Life Sci. 88(11-12)
  
  Pages: 529-534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Involvement of the cellular prion protein in the migration of brain microvascular e ndothelial cells2011
- Author(s)
  Watanabe T, Yasutaka Y, Nishioku T, Ku sakabe S, Futagami K, Yamauchi A, Kata oka Y
- Journal Title
  
  Neurosci Lett.
  
  Volume: 496(2) Issue: 2 Pages: 121-4
- DOI
  10.1016/j.neulet.2011.03.096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590255, KAKENHI-PROJECT-23790311
[Journal Article] Autocrine and paracrine up-regulation of blood-brain barrier function by plasminogen activator inhibitor-1.2011
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Oda M, Harada E, Watanabe T, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Microvasc Res. 81(1)
  
  Pages: 103-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Autocrine and paracrine up-regulation of blood-brain barrier function by plasminogen activator inhibitor-1.2010
- Author(s)
  Dohgu S, Takata F, Matsumoto J, Oda M,Harada E, Watanabe T, Nishioku T, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Microvascular Research
  
  Volume: 81(1) Pages: 103-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Disruption of the blood-brain barrier in collagen-induced arthritic mice.2010
- Author(s)
  Nishioku T, Yamauchi A, Takata F, Watanabe T, Furusho K, Shuto H, Dohgu S, Kataoka Y.
- Journal Title
  
  Neuroscience Letters
  
  Volume: 482(3) Pages: 208-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Tumor necrosis factor-alpha mediates the blood-brain barder dysfunction induced by activated microglia in mouse brain microvascular endothelial cells2010
- Author(s)
  Nishioku T, Matsumoto J, Dohgu S, Sumi N, Miyao K, Takata F, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Journal of Pharmacological Sciences 112(2)
  
  Pages: 251-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Lipopolysaccharide-Activated Microglia Induce Dysfunction of the Blood-Brain Bamer in Rat Microvascular Endothelial Cells Co-Cultured with Microglia2010
- Author(s)
  Sumi N, Nishioku T, Takata F, Matsumoto J, Watanabe T, Shuto H, Yamauchi A, Dohgu S, Kataoka Y.
- Journal Title
  
  Cellular and Molecular Neurobiology 30(2)
  
  Pages: 247-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Lipopolysaccharide-activated microglia induce dysfunction of the blood-brain barrier in rat microvascular endothelial cells co-cultured with microglia.2010
- Author(s)
  Sumi N, Nishioku T, Takata F, Matsumoto J, Watanabe T, Shuto H, Yamauchi A, Dohgu S, Kataoka Y.
- Journal Title
  
  Cell Mol Neurobiol. 30(2)
  
  Pages: 247-253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Cyclosporin A induces hyperpermeability of the blood-brain barrier by inhibiting autocrine adrenomedullin-mediated up-regulation of endothelial barrier function.2010
- Author(s)
  Dohgu S, Sumi N, Nishioku T, Takata F, Watanabe T, Naito M, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  Eur J Pharmacol. 644(1-3)
  
  Pages: 5-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Cyclosporin A induces hyperpermeability of the blood-brain barrier by inhibiting autocrine adrenomedullin-mediated up-regulation of endothelial barrier function.2010
- Author(s)
  Dohgu S, Sumi N, Nishioku T, Takata F, Watanabe T, Naito M, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 644(1-3) Pages: 5-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Tumor necrosis factor-alpha mediates the blood-brain barrier dysfunction induced by activated microglia in mouse brain microvascular endothelial cells.2010
- Author(s)
  Nishioku T, Matsumoto J, Dohgu S, Sumi N, Miyao K, Takata F, Shuto H, Yamauchi A, Kataoka Y.
- Journal Title
  
  J Pharmacol Sci. 112(2)
  
  Pages: 251-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Disruption of the blood-brain barrier in collagen-induced arthritic mice.2010
- Author(s)
  Nishioku T, Yamauchi A, Takata F, Watanabe T, Furusho K, Shuto H, Dohgu S, Kataoka Y.
- Journal Title
  
  Neurosci Lett. 482(3)
  
  Pages: 208-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Detachment of brain pericytes from the basal lamina is involved in disruption of the blood-brain bamer caused by lipopolysaccharide-induced sepsis in mice2009
- Author(s)
  Nishioku T, Dohgu S, Takata F, Eto T, Ishikawa N, Kodama K.B, Nakagawa S, Yamauchi A, Kataoka Y.
- Journal Title
  
  Cellular and Molecular Neurobiology 29(3)
  
  Pages: 309-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Detachment of brain pericytes from the basal lamina is involved in disruption of the blood-brain barrier caused by lipopolysaccharide-induced sepsis in mice.2009
- Author(s)
  Nishioku T, Dohgu S, Takata F, Eto T, Ishikawa N, Kodama K.B, Nakagawa S, Yamauchi A, Kataoka Y.
- Journal Title
  
  Cell Mol Neurobiol. 29(3)
  
  Pages: 309-316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Angiotensin II AT1 blockade reduces the lipopolysaccharide-induced innate immune response in rat spleen2009
- Author(s)
  Sanchez-Lemus E, Benicky J, Pavel J, Larrayoz IM, Zhou J, Baliova M, Nishioku T, Saavedra JM.
- Journal Title
  
  Amedcan journal of physiology. Regulatory, integrative and comparative physiology 296(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Journal Article] Angiotensin II AT1 blockade reduces the lipopolysaccharide-induced innate immune response in rat spleen.2009
- Author(s)
  Sanchez-Lemus E, Benicky J, Pavel J, Larrayoz IM, Zhou J, Baliova M, Nishioku T, Saavedra JM.
- Journal Title
  
  Am J Physiol Regul Integr Comp Physiol. 296(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790526
[Presentation] 没食子酸エピガロカテキンによる破骨細胞分化抑制機構のメカニズム2018
- Author(s)
  久保利樹、宇都拓洋、正山征洋、西奥剛
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2018
- Data Source
  KAKENHI-PROJECT-16K08567
[Presentation] フマル酸ジメチルによる破骨細胞分化抑制機構の解析2018
- Author(s)
  沖園竜弥、川本百実、坂井詠子、岡元邦彰、筑波隆幸、西奥剛
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2018
- Data Source
  KAKENHI-PROJECT-16K08567
[Presentation] フマル酸ジメチルによる破骨細胞分化抑制作用2016
- Author(s)
  川本百実，西奥剛，坂井詠子，岡元邦彰，筑波隆幸，山田勝士
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2016
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-16K08567
[Presentation] BMP4による糖尿病併発動脈硬化巣の増悪とマクロファージの酸化LDL取り込み促進2013
- Author(s)
  金岡祐輝、古賀允久、地下隆介、塚本安那、手島奈央、久保尚加、大城戸友麻、西奥剛、山内淳史、片岡泰文
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-23790311
[Presentation] S100A4 is a causative factor for disruption of the blood-brain barrier in collagen-induced arthritic mice2012
- Author(s)
  Tsuyoshi Nishioku, Atsushi Yamauchi, and Yasufumi Kataoka
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23790311
[Presentation] クプリゾン誘発脱髄動物モデルの大脳白質におけるCD147の発現変動2012
- Author(s)
  津曲康輔、西奥剛、寺澤真理子、片岡泰文
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2012
- Place of Presentation
  神戸
- Year and Date
  2012-09-01
- Data Source
  KAKENHI-PROJECT-23790311
[Presentation] 糖尿病病態下の動脈硬化巣におけるBMP4の役割2012
- Author(s)
  古賀允久、金岡祐輝、地下隆介、西奥剛、山内淳史、片岡泰文
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-23790311
[Presentation] S100A4 is a causative factor for disruption of the blood-brain barrier in collagen-induced arthritic mice2012
- Author(s)
  西奥剛、山内淳史、片岡泰文
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-23790311
[Presentation] コラーゲン誘導関節炎マウスの滑膜におけるCyclophilinAとCD147の発現増加とその局在2011
- Author(s)
  寺澤真理子、西奥剛、三浦哲平、津曲康輔、山内淳史、片岡泰文
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-23790311
[Presentation] 関節リウマチの炎症性細胞浸潤機構におけるシクロフィリンAの役割2011
- Author(s)
  大石裕晃、西奥剛、片岡泰文
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2011
- Place of Presentation
  北里大学薬学部白金キャンパス（東京）
- Data Source
  KAKENHI-PROJECT-23790311
[Presentation] 関節リウマチの炎症性細胞浸潤機構におけるシクロフィリンAの役割2011
- Author(s)
  大石裕晃、西奥剛、片岡泰文
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2011
- Place of Presentation
  東京
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-23790311
[Presentation] コラーゲン誘導関節炎マウスの滑膜におけるCyclophilin AとCD147の発現増加とその局在2011
- Author(s)
  寺澤真理子、西奥剛、三浦哲平、津曲康輔、山内淳史、片岡泰文
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  KKRホテル博多（福岡）
- Data Source
  KAKENHI-PROJECT-23790311
[Presentation] コラーゲン誘導関節炎マウスのパンヌスにおけるCyclophilin AとCD147の発現増加とその局在2011
- Author(s)
  三浦哲平、西奥剛、大石裕晃、津曲康輔、山内淳史、首藤英樹、片岡泰文
- Organizer
  第131回日本薬学会年会
- Place of Presentation
  (誌上開催)
- Data Source
  KAKENHI-PROJECT-21790526
[Presentation] 関節炎モデルマウスの血液脳関門機能障害におけるS100A4の役割2011
- Author(s)
  冨田彩乃、西奥剛、大石裕晃、三浦哲平、道具伸也、山内淳史、首藤英樹、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Data Source
  KAKENHI-PROJECT-21790526
[Presentation] 関節炎モデルマウスにおける血液脳関門障害2010
- Author(s)
  古庄弘宜, 西奥剛, 三浦哲平, 冨田彩乃, 道具伸也, 高田芙友子, 渡辺拓也, 山内淳史, 首藤英樹, 片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪市
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21790526
[Presentation] 関節炎モデルマウスの血液脳関門機能障害におけるS100A4の役割2010
- Author(s)
  冨田彩乃、西奥剛、大石裕晃、三浦哲平、道具伸也、山内淳史、首藤英樹、片岡泰文
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  誌上
- Year and Date
  2010-03-24
- Data Source
  KAKENHI-PROJECT-21790526
[Presentation] コラーゲン誘導関節炎マウスのパンヌスにおけるCyclophilin AとCD147の発現増加とその局在2010
- Author(s)
  三浦哲平、西奥剛、大石裕晃、津曲康輔、山内淳史、首藤英樹、片岡泰文
- Organizer
  第131回日本薬学会年会
- Place of Presentation
  誌上
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21790526
[Presentation] 関節炎モデルマウスにおける血液脳関門障害2010
- Author(s)
  古庄弘宜, 西奥剛, 三浦哲平, 冨田彩乃, 道具伸也, 高田芙友子, 渡辺拓也, 山内淳史, 首藤英樹, 片岡泰文
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪市)
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21790526
[Presentation] Activation of microglia and migration of brain pericytes are involved in disruption of the blood-brain barrier caused by lipopolysaccharide2009
- Author(s)
  Tsuyoshi Nishioku, Noriko Sumi, Shinya Dohgu, Fuyuko Takata, Takashi Machida, Hideki Shuto, Atsushi Yamauchi, Yasufumi Kataoka
- Organizer
  第1回アジア神経精神薬理学会
- Place of Presentation
  京都市
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21790526
[Presentation] Activation of microglia and migration of brain pericytes are involved in disruption of the blood-brain barrier caused by lipopolysaccharide2009
- Author(s)
  Tsuyoshi Nishioku, Noriko Sumi, Shinya Dohgu, Fuyuko Takata, Takashi Machida, Hideki Shuto, Atsushi Yamauchi, Yasufumi Kataoka
- Organizer
  第1回アジア神経精神薬理学会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21790526
[Presentation] Detachment of brain pericytes from the basal lamina is involved in disruption of the blood-brain barrier caused by lipopolysaccharide-induced sepsis in mice2009
- Author(s)
  Tsuyoshi Nishioku, Shinya Dohgu, Fuyuko Takata, Shinsuke Nakagawa, Hideki Shuto, Atsushi Yamauchi, Masami Niwa, Yasufumi Kataoka
- Organizer
  8^<th> Cerebral Vascular Biology
- Place of Presentation
  仙台エクセルホテル東急(仙台市)
- Year and Date
  2009-06-30
- Data Source
  KAKENHI-PROJECT-21790526
[Presentation] Detachment of brain pericytes from the basal lamina is involved in disruption of the blood-brain barrier caused by lipopolysaccharide-induced sepsis in mice.2009
- Author(s)
  Tsuyoshi Nishioku, Shinya Dohgu, Fuyuk o Takata, Shinsuke Nakagawa, Hideki Shuto, Atsushi Yamauchi, Masami Niwa, Yasufumi Kataoka
- Organizer
  8^<th> Cerebral Vascular Biology
- Place of Presentation
  仙台市
- Year and Date
  2009-06-30
- Data Source
  KAKENHI-PROJECT-21790526
[Presentation] 糖尿病病態下の動脈硬化巣におけるBMP4の役割
- Author(s)
  古賀允久、金岡祐輝、地下隆介、西奥剛、山内淳史、片岡泰文
- Organizer
  第６５回日本薬理学会西南部会
- Place of Presentation
  熊本大学薬学部（熊本）
- Data Source
  KAKENHI-PROJECT-23790311
[Presentation] 破骨細胞分化におけるCD147の役割
- Author(s)
  西奥剛，寺澤真理子，馬場美咲，山田勝士，片岡泰文
- Organizer
  日本薬学会　第１３５年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460349
[Presentation] ＢＭＰ４による糖尿病併発動脈硬化巣の増悪とマクロファージの酸化ＬＤＬ取り込み促進
- Author(s)
  金岡祐輝、古賀允久、地下隆介、塚本安那、手島奈央、久保尚加、大城戸友麻、西奥剛、山内淳史、片岡泰文
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-23790311
[Presentation] クプリゾン誘発脱髄モデル動物の大脳白質におけるCD147の発現変動
- Author(s)
  津曲康輔、西奥剛、寺澤真理子、片岡泰文
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2012
- Place of Presentation
  神戸学院大学（神戸）
- Data Source
  KAKENHI-PROJECT-23790311

1. YAMAUCHI Atsushi (90341453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KOGA Mitsuhisa (60570801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 岡元邦彰 (10311846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 筑波隆幸 (30264055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 佐々木茂貴 (10170672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 村瀬裕貴 (10814486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山田耕平 (40583232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 吉田達貞 (80527557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 片岡泰文

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
10. 道具伸也

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
11. 高田芙友子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 首藤英樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Nishioku Tsuyoshi 西奥 剛

NISHIOKU Tsuyoshi 西奥 剛

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カテプシンEによるCD147のプロセッシングを介した関節リウマチの骨破壊機構Principal Investigator

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Basic research into nucleic acid drugs that induce readthrough by chemically modifying the adenosine at the premature termination codon

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Molecular mechanism of bone destruction in rheumatoid arthritis based on CD147Principal Investigator

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Function of CD147 in white matter lesionsPrincipal Investigator

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Function of cyclophilin A and CD147 in rheumatoid arthritisPrincipal Investigator

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Monoclonal antibody against tumour necrosis factor alpha-associated leukoencephalopathy in rheumatoid arthritisPrincipal Investigator

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[Journal Article] Berberine Induces Apoptotic Cell Death via Activation of Caspase-3 and -8 in HL-60 Human Leukemia Cells: Nuclear Localization and Structure?Activity Relationships2017

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[Journal Article] CD147 promotes the formation of functional osteoclasts through NFATc1 signalling.2016

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[Journal Article] Paracellular Barrier and Tight Junction Protein Expression in the Immortalized Brain Endothelial Cell Lines bEND.3, bEND.5 and Mouse Brain Endothelial Cell 42013

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[Journal Article] BMP4 is increased in the aortas of diabetic ApoE knockout mice andenhances uptake of oxidized low density lipoprotein into peritoneal macrophages.2013

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[Journal Article] Atorvastatin stimulates neuroblastoma cells to induce neurite outgrowth by increasing cellular prion protein expression.2012

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[Journal Article] Cyclophilin A secreted from fibroblast-like synoviocytes is involved in the induction of CD147 expression in macrophages of mice with collagen-induced arthritis.2012

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[Journal Article] Lipopolysaccharide-activated microglia lower P-glycoprotein function in brain microvascular endothelial cells.2012

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[Journal Article] Autocrine and paracrine up-regulation of blood-brain barrier function by plasminogen activator inhibitor-1.2011

Nishioku Tsuyoshi 西奥剛

NISHIOKU Tsuyoshi 西奥剛