SASAKI Shigeki 佐々木茂貴

… Alternative Names

佐々木茂喜ササキシゲキ

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Researcher Number	10170672
Other IDs	https://orcid.org/0000-0003-2013-2441
External Links
Affiliation (Current)	2025: 長崎国際大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 長崎国際大学, 薬学部, 教授 2016 – 2019: 九州大学, 薬学研究院, 教授 2016: 九州大学, 大学院薬学研究院, 教授 2012 – 2015: 九州大学, 薬学研究科(研究院), 教授 2011: 九州大学, 薬学研究院, 教授 … More 2006 – 2011: 九州大学, 大学院・薬学研究院, 教授 2006: 九州大学, 大学院薬学研究院, 教授 2002 – 2005: 九州大学, 薬学研究院, 教授 2002 – 2003: Faculty of Pharmaceutical Sciences, Prof., 大学院・薬学研究院, 教授 2001: 九州大学, 大学院・薬学研究院, 助教授 2000 – 2001: KYUSHU UNIVERSITY, FACULTY OF PHARMACEUTICAL SCIENCES, ASSOCIATE PROFESSOR, 薬学研究院, 助教授 1999: 九州大学, 薬学研究科, 助教授 1991 – 1998: 九州大学, 薬学部, 助教授 1988 – 1989: 東京大学, 薬学部, 助手 1986: Assistant, Faculty of Pharmaceutical Sciences, University of Tokyo, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Chemical pharmacy / Chemical pharmacy / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Science and Engineering / Medium-sized Section 47:Pharmaceutical sciences and related fields / Chemical pharmacy / Drug development chemistry Except Principal Investigator Chemical pharmacy / Biological pharmacy / Science and Engineering … More / Chemical pharmacy / Radiation science / Pediatrics / 環境影響評価(含放射線生物学) Less
Keywords	Principal Investigator 遺伝子発現制御 / 認識分子 / アンチジーン / オリゴヌクレオチド / アンチセンス / クロスリンク / RNA / DNA / 3本鎖DNA / 有機化学 … More / 機能性核酸 / DNA結合分子 / 点変異 / RNA編集 / リードスルー / RNA化学修飾 / 官能基転移反応 / 核酸 / 薬学 / triplex DNA / ゲノム標的化学 / HYDROPHOBIC AMINO ACIDS / DNA-BINDING MOLECULES / DUPLEX DNA / PEPTIDE LIBRARY / SOLID-STATE LIBRARY / COMBINATORIAL CHEMISTRY / 制限酵素 / 2本鎖DNA / 人工核酸 / 酸化損傷塩基 / 機能性人工核酸 / 核酸医薬 / マイナーグルーブ結合 / マイナーグループ結合 / ヘキスト / 官能基転移 / 2-aminopurine誘導体 / 遺伝子発現阻害 / 金属錯体 / DNA配列特異的結合 / テロメラーゼ / ナンセンス変異 / 未熟停止コドン / 化学修飾mRNA / FMR1 / 遺伝子発現促進 / 分子集積薬 / 低分子リガンド / CGGリピー / 翻訳活性化 / 転写活性化 / 低分子創薬 / CGGリピート / FMR1遺伝子 / リピート病 / 脆弱X症候群 / クリック反応 / シトシン脱アミノ化 / 機能性人工ヌクレオシド / 非細胞翻訳 / 化学反応性人工核酸 / 編集 / 変異 / ペプチド / 翻訳 / 化学修飾 / 核酸化学 / 転写阻害 / 協同作用 / 自己集積 / リピートDNA / 選択的化学修飾 / 分子認識 / 部位特異的RNA修飾 / artificial nucleoside analog / minor-groove binder / nitrosyl transfer / duplex DNA / reactive molecule / molecular recognition / Genome-targeting / 人工核酸誘 / ニトロシル基転移 / 反応分子 / 認識 / genome-targeting chemistry / expansion of triplex code / recognition molecule / inhibition of gene expression / recognition of duplex sequence / antigene / artificial nucleobase analog / 2本鎖DNA認識 / アンチジーン法 / バイオテクノロジー / Hoogsteen水素結合 / 三本鎖DNA / 認識コードの拡張 / 2本鎖DNA配列認識 / 人工塩基 / DNA結合 / ビスピロール / ビスフラン / ビステトラヒドロフラン / 新規リガンド / DNA配列認識 / 配列選択性 / 阻害剤 / ペンタペプチドライブラリー / 疎水性アミノ酸 / ペプチドライブラリー / 固相ライブラリー / コンビナトリアルケミストリー / hydrogen bonding / nucleic acid / non-natural base / triplex / triple helix / 遺伝発現制御 / トリプルヘリックス / 3重鎖DNA / トリプルヘッリクス / 重鎖DNA / multisubstrate / bisindol / Inhibitor / cell cycle / cdc2 kinase / Protein Kinase / 阻害薬 / 細胞周期阻害 / 疑似基質構造 / ビスインドール / 酵素阻害剤 / 細胞周期 / cdc2キナーゼ / プロテインキナーゼ / Stereoselective Synthesis / Cell growth inhibition / Tumor cell recognition molecule / Antitumor Activity / Bullatacin / Acetogenin / 立体選択的合成 / 細胞増殖抑制 / がん細胞認識分子 / 抗腫瘍活性 / ブラタシン / アセトゲニン / 選択的捕捉分子 / ８－チオグアニン / ８－ニトログアニン / ８－オキソグアニン / 活性窒素 / 活性酸素 / 蛍光検出 / 共有結合的捕捉 / ８－チオグアノシン / ８－ニトログアノシン / ８－オキソグアノシントリリン酸 / ８－オキソグアノシン / 8-ニトログアノシンモノリンリン酸 / ８-オキソグアノシン / 検出 / 8-ﾆﾄﾛｸﾞｱﾉｼﾝﾓﾉﾘﾝﾘﾝ酸 / 8-オキソグアノシン / 8-ニトログアノシン / フォトクロミックリガンド / Z-DNA / DNA高次構造 / ZーDNAォトクロミックリガンド / 生体関連物質 / ミトコンドリア / ２型糖尿病 / 疾患モデルマウス / 2型糖尿病 / ナノメディスン / 薬物送達 / 協奏的結合 / 繰り返しDNA配列 / チオール-ジスルフィド平衡 / グルタチオン / 平衡シフト / チオールージスルフィド平衡 / マイナーグルーブ / 動的コンビナトリアル化学 / マイナーグループバインダー / インテリジェント人工核酸 / インテリジェント / ナノ医薬 / インテリジェント核酸 / 反応性分子 / ゲノム標的分子 / 遺伝子修復 / 脱アミノ化 / N-ニトロシル / S,N-転移反応 / S-ニトロシル / デオキシリオリゴヌクレオチド / ジアミノフラン / ジアミノビステトラヒドロフラン / 人口核酸 … More Except Principal Investigator DNA複製 / 分子認識 / DNA replication / DnaA protein / DNAポリメラーゼ / 抗菌剤 / 大腸菌 / DNA損傷 / がん / 遺伝子 / パーキンソン / ペプチドゲル / 核酸 / 脂質ペプチド / 抗酸化 / シトリン欠損症 / ペプチド脂質 / 感染症 / 分子組織化薬 / コントロールドリリース / PPARα / 癌悪液質 / サルコペニア / 自己組織化薬 / 抗酸化薬 / 脂質ゲル化 / オリゴ核酸 / 短鎖脂肪酸 / アミノ酸 / 抗酸化剤 / 自己組織化創薬 / 水素結合 / 8-オキソグアノシン / 8-チオグアノシン / 8-ニトログアノシン / 酸化損傷塩基 / 捕捉分子 / Inclusion of Cationic Guests / Host-Guest Chemistry / Inclusion Complex / Diarylmethane / Molecular Recognition / Water-soluble Cyclophanes / 電荷相互作用 / 疎水性相互作用 / クロマトグラフィー用担体 / ホストゲスト錯体 / アニオン性フィクロファン / カチオン性シクロファン / カチオン性基質の取り込み / ホスト-ゲスト化学 / 包接錯体 / ジアリ-ルメタン / 水溶性シクロファン / Asymmetric Deprotonation Reaction / Chiral Lewis Acid; Chiral Base / Asymmetric Alkylation / Enantioselective Asymmetric Synthesis / Asymmetric Michel Reaction / β,β-ジ置換カルボン酸 / α,α-ジ置換-β-ケトエステル / エナミン / 不斉脱プロトン化 / エナンチオ選択的反応 / マイケル反応 / 不斉合成 / 不斉合成子 / 不斉脱プロトン化反応 / 不斉塩基 / 不斉ルイス酸 / 不斉アルキル化 / エナンチオ選択的不斉合成 / 不斉マイケル反応 / Gene intervention / Radio sensitivity / Antigene / DNA recombination / Synthetic oligomer / Cell death / DNA repair / DNA damage / DNA組み換え / 遺伝子導入 / 放射線感受性 / アンチジーン / DNA組換え / 合成オリゴマー / 細胞死 / DNA修復系 / oriC replication / the dnaN genen / DNA polymerase III / Esherichia coli / 部位特異的変異 / Walkerモチーフ / ATP / DnaAタンパク / DnaA / DNA合成開始 / oriC複製 / oriC plasmid / indigo / ATP-binding / Escherichia coli. / chromosomal DNA / dnaA変異株 / 脂質 / oriC / ovic複製 / 脂質クラスター / DNA合成阻害剤 / oriCプラスミド / 医薬品開発 / インジゴ / ATP結合 / DnaA蛋白 / 部位特異的変異導入 / hprt遺伝子 / GFP / オリゴヌクレオチド / 遺伝子修復治療 / 酸化ヌクレオチド / 浄化 / ミューテーター / 酸化ストレス / ヌクレオチドプール / 突然変異 Less

Basic research into nucleic acid drugs that induce readthrough by chemically modifying the adenosine at the premature termination codonPrincipal Investigator
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Nagasaki International University
Development of small molecule drugs for fragile X syndrome based on ligands that cooperatively accumulate on the CGG repeats.Principal Investigator
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Nagasaki International University
Molecular design of innovative drugs based on molecular assembly
- Principal Investigator
  
  Nagasaki Yukio
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
- Research Institution
  University of Tsukuba
Development of the artificial oligonucleotides for the RNA pinpoint modification and the application to RNA editingPrincipal Investigator
- Principal Investigator
  
  Sasaki Shigeki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Nagasaki International University
  Kyushu University
Development of small molecular ligands for simultaneous binding to the multiple sites of DNAPrincipal Investigator
- Principal Investigator
  
  Sasaki Shigeki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
Chemically reactive oligonucleotides for site-specific modification of RNA and artificial RNA editingPrincipal Investigator
- Principal Investigator
  
  Sasaki Shigeki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
Development of capture probes for the signaling nucleotide molecules in cells
- Principal Investigator
  
  FUCHI Yasufumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
Development of recognition molecules for 8-oxidized guanosine derivativesPrincipal Investigator
- Principal Investigator
  
  Sasaki Shigeki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
Development of the selective capture molecule for 8-nitroguanosinePrincipal Investigator
- Principal Investigator
  
  SASAKI Shigeki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
官能基転移反応によるＲＮＡの化学修飾法の開発Principal Investigator
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
Photochromic DNA Binding Ligands for B and Z-DNA InterconversionPrincipal Investigator
- Principal Investigator
  
  SHIGEKI Sasaki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
Study on the innovative molecular-targeting medicine based on the nano-DDS encapsulating intelligent artificial oligonucleotidesPrincipal Investigator
- Principal Investigator
  
  SASAKI Shigeki
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyushu University
異常に長い繰り返し配列のDNA上に金属イオンを解して自己集積する分子の開発Principal Investigator
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
動的コンビナトリアル化学によるDNA高次構造認識分子の検索Principal Investigator
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
Development of Genome-Targeting Molecules with Ability of Chemical Reactivity and Application to Intelligent Nano-MedicinePrincipal Investigator
- Principal Investigator
  
  SASAKI Shigeki
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
ゲノムのピンポイント修飾を目指したDNA配列特異的な官能基転移反応の検討Principal Investigator
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
Design of functional molecules for selective recognition and reaction to the duplex DNAPrincipal Investigator
- Principal Investigator
  
  SASAKI Shigeki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYUSHU UNIVERSITY
次世代遺伝子治療の開発研究
- Principal Investigator
  
  原寿郎
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University
機能性核酸DNA複合体形成によるシンクロナイゼーション活性化Principal Investigator
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyushu University
Development of gene-mediated radiotherapy for tumors
- Principal Investigator
  
  TSUZUKI Teruhisa
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyushu University
Design of the new recognition molecules for the formation of triplex helix DNA at any predetermined sites.Principal Investigator
- Principal Investigator
  
  SASAKI Shigeki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
GCおよびAT選択的な新規リガンドを基本とするDNA配列認識分子の創製Principal Investigator
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyushu University
Development of the New Recognition Molecules of DNA Sequences Based on the GC- and AT-Selective LigandsPrincipal Investigator
- Principal Investigator
  
  SASAKI Shigeki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYUSHU UNIVERSITY
新しいGC配列特異的DNA結合分子の開発と金属イオンによる結合の制御Principal Investigator
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
テロメラーゼを標的とする新しい制癌手法の研究Principal Investigator
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Molecular design of inhibitors for DNA replication in Escherichia coli
- Principal Investigator
  
  SEKIMIZU Kazuhisa
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KYUSHU UNIVERSITY
Random Search of DNA Recognition Molecules by the Use of the New Combinatorial TechnologyPrincipal Investigator
- Principal Investigator
  
  SASAKI Shigeki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYUSHU UNIVERSITY
テロメラーゼを標的とする新しい制癌手法の研究Principal Investigator
- Principal Investigator
  
  佐々木茂貴
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
酸化およびアルキル化DNA損傷を防ぐヒト酵素の精製と解析
- Principal Investigator
  
  早川浩
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyushu University
Design and Synthesis of New Recognition Molecules for the Sequence-Selective Triple Helical DNA FormationPrincipal Investigator
- Principal Investigator
  
  SASAKI Shigeki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYUSHU UNIVERSITY
Screening of inhibitors of DNA replication by using the oriC plasmid replication system of Escherichia coli
- Principal Investigator
  
  SEKIMIZU Kazuhisa
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  KYUSHU UNIVERSITY
MULTI-SUBSTRATE TYPE INHIBITORS FOR CDC2 KINASE AND THEIR EVALUATION AS SELECTIVE CELL-CYCLE INHIBITORSPrincipal Investigator
- Principal Investigator
  
  SASAKI Shigeki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYUSHU UNIVERSITY
新規な構造を持つアセトゲニン類をリード化合物とする新しいがん細胞認識分子の探索Principal Investigator
- Principal Investigator
  
  SASAKI Shigeki
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYUSHU UNIVERSITY
DESIGN, SYNTHESIS, AND PROPERTIES OF CYCLOPHANES AS HOSTS HAVING ABILITY OF FORMING INCLUSION COMPLEXES
- Principal Investigator
  
  KOGA Kenji
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  FACULTY OF PHARMACEUTICAL SCIENCES, THE UNIVERSITY OF TOKYO
Development of Novel Asymmetric Synthetic Reactions
- Principal Investigator
  
  KOGA Kenji
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  University of Tokyo

[Book] 中分子創薬に資するペプチド・核酸・糖鎖の合成技術第Ⅲ編　核酸2018
- Author(s)
  佐々木茂貴
- Total Pages
  317
- Publisher
  シーエムシー出版
- ISBN
  9784781313207
- Data Source
  KAKENHI-PROJECT-15H04633
[Book] 遺伝子医学MOOK(32)　難病研究up-to-date2017
- Author(s)
  佐々木茂貴
- Total Pages
  288
- Publisher
  メディカルドゥ
- ISBN
  9784944157624
- Data Source
  KAKENHI-PROJECT-15H04633
[Book] 医療・診断・創薬の化学2017
- Author(s)
  佐々木茂貴
- Total Pages
  194
- Publisher
  日本化学会化学同人
- ISBN
  9784759813845
- Data Source
  KAKENHI-PROJECT-15H04633
[Book] 核酸医薬の創製と応用展開2016
- Author(s)
  佐々木茂貴
- Total Pages
  278
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-15H04633
[Book] Molecular Design for Specific Recognition and Reaction in Genome-Targeting Chemistry in Frontiers in Organic Chemistry2005
- Author(s)
  Shigeki Sasaki, Fumi Nagatsugi
- Publisher
  Bentham Science Publishers Ltd
- Data Source
  KAKENHI-PROJECT-15659004
[Book] Molecular Design for Specific Recognition and Reaction in Genome-Targeting Chemistry in Frontiers in Organic Chemistry2005
- Author(s)
  Shigeki Sasaki, Fumi Nagatsugi
- Publisher
  Bentham Science Publishers Ltd
- Data Source
  KAKENHI-PROJECT-15390007
[Book] Molecular Design for Specific Recognition and Reaction in Genome-Targeting Chemistry, Frontiers in Organic Chemistry2005
- Author(s)
  S.Sasaki, F.Nagatsugi
- Publisher
  Bentham Science Publishers
- Data Source
  KAKENHI-PROJECT-17209001
[Book] ゲノムケミストリー第2章6,2本鎖DNA形成をトリガーとするシンクロナイゼーション活性化によるクロスリンク反応 89-100頁(関根光雄、斎藤烈編)2003
- Author(s)
  佐々木茂貴
- Total Pages
  240
- Publisher
  講談社サイエンティフィク
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Inhibition of transcription and antiproliferative effects in a cancer cell line using antigene oligonucleotides containing artificial nucleoside analogues2023
- Author(s)
  Wang Lei、Notomi Ryotaro、Sasaki Shigeki、Taniguchi Yosuke
- Journal Title
  
  RSC Medicinal Chemistry
  
  Volume: 14 Issue: 8 Pages: 1482-1491
- DOI
  10.1039/d3md00139c
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21354, KAKENHI-PROJECT-23K27301
[Journal Article] Artificial Host Molecules to Covalently Capture 8-Nitro-cGMP in Neutral Aqueous Solutions and in Cells2021
- Author(s)
  Y. Fuchi, H. Murase, R. Kai, K. Kurata, S. Karasawa, and S. Sasaki*
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 32 Issue: 2 Pages: 385-393
- DOI
  10.1021/acs.bioconjchem.1c00012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07016, KAKENHI-PROJECT-20K15398, KAKENHI-PROJECT-20K15963, KAKENHI-PROJECT-18H02558
[Journal Article] Development of MTH1-Binding Nucleotide Analogs Based on 7,8-Dihalogenated 7-Deaza-dG Derivatives2021
- Author(s)
  Shi Hui、Ishikawa Ren、Heh Choon Han、Sasaki Shigeki、Taniguchi Yosuke
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 3 Pages: 1274-1274
- DOI
  10.3390/ijms22031274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02558, KAKENHI-PROJECT-19H03351
[Journal Article] Enhancements in the utilization of antigene oligonucleotides in the nucleus by booster oligonucleotides2020
- Author(s)
  Wang Lei、Okamura Hidenori、Sasaki Shigeki、Taniguchi Yosuke
- Journal Title
  
  Chemical Communications
  
  Volume: 56 Issue: 67 Pages: 9731-9734
- DOI
  10.1039/d0cc04240d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02558, KAKENHI-PROJECT-19H03351
[Journal Article] Development of novel C-nucleoside analogues for the formation of antiparallel-type triplex DNA with duplex DNA that includes TA and dUA base pairs2020
- Author(s)
  Taniguchi Yosuke、Magata Yuya、Osuki Takayuki、Notomi Ryotaro、Wang Lei、Okamura Hidenori、Sasaki Shigeki
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 18 Issue: 15 Pages: 2845-2851
- DOI
  10.1039/d0ob00420k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02558, KAKENHI-PROJECT-19H03351
[Journal Article] Synthesis of Nucleoside Derivatives of N-Acetyl-7-nitroindoline, Their Incorporation into the DNA Oligomer, and Evaluation of Their Photoreactivity in the DNA/RNA Duplex2020
- Author(s)
 Kikuta Kenji、Barta Jan、Taniguchi Yosuke、Sasaki Shigeki
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 68 Issue: 12 Pages: 1210-1219
- DOI
 10.1248/cpb.c20-00594
- NAID
 130007948430
- ISSN
 0009-2363, 1347-5223
- Year and Date
 2020-12-01
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-18H02558
[Journal Article] Protection of all cleavable sites of DNA with the multiple CGCG or continuous CGG sites from the restriction enzyme, indicative of simultaneous binding of small ligands2020
- Author(s)
  Murase Hirotaka、Wakisaka Gentaro、Noguchi Tomoharu、Sasaki Shigeki
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28 Issue: 20 Pages: 115730-115730
- DOI
  10.1016/j.bmc.2020.115730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15398, KAKENHI-PROJECT-18H02558
[Journal Article] Synthesis of C-nucleoside analogues based on the pyrimidine skeleton for the formation of anti-parallel-type triplex DNA with a CG mismatch site2020
- Author(s)
  Notomi Ryotaro、Wang Lei、Osuki Takayuki、Okamura Hidenori、Sasaki Shigeki、Taniguchi Yosuke
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28 Issue: 23 Pages: 115782-115782
- DOI
  10.1016/j.bmc.2020.115782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02558, KAKENHI-PROJECT-19H03351
[Journal Article] Study of the Inducible Cross-Linking Reaction to mRNA and the Effect on the Translation2019
- Author(s)
  Kenji Kikuta, Yosuke Taniguchi, Shigeki Sasaki
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 67 Issue: 8 Pages: 877-883
- DOI
  10.1248/cpb.c19-00337
- NAID
  130007686359
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2019-08-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02558
[Journal Article] Luminescent europium sensors for specific detection of 8-oxo-dGTP by time-gated fluorescence2018
- Author(s)
  Fuchi Yasufumi、Fukuda Takashi、Sasaki Shigeki
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 印刷中 Issue: 12 Pages: 3254-3260
- DOI
  10.1016/j.bmc.2018.04.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04633, KAKENHI-PROJECT-17K08212, KAKENHI-PROJECT-18H02558
[Journal Article] Evaluation of simultaneous binding of Chromomycin A3 to the multiple sites of DNA by the new restriction enzyme assay2018
- Author(s)
  Hirotaka Murase, Tomoharu Noguchi, Shigeki Sasaki
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 28 Issue: 10 Pages: 1832-1835
- DOI
  10.1016/j.bmcl.2018.04.013
- Data Source
  KAKENHI-PROJECT-16K15099, KAKENHI-PROJECT-18H02558
[Journal Article] Efficient Thymidine-Selective DNA Interstrand Photo-activated Crosslinking by the 6-Thioguanine Connected via an Ethylene-Linker to the 2′-Deoxyribose Unit2016
- Author(s)
 Nishioka Takamasa, Oshiro Ikuya, Onizuka Kazumitsu, Taniguchi Yosuke and Sasaki S
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 64 Issue: 9 Pages: 1315-1320
- DOI
 10.1248/cpb.c16-00310
- NAID
 130005261564
- ISSN
 0009-2363, 1347-5223
- Language
 English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
 KAKENHI-PROJECT-15H04633
[Journal Article] Aminopyridinyl-pseudodeoxycytidine derivatives selectively stabilize antiparalleltriplex DNA with multiple CG inversion sites2016
- Author(s)
  Okamura Hidenori, Taniguchi Yosuke, Sasaki Shigeki
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 128 Issue: 40 Pages: 12633-12637
- DOI
  10.1002/ange.201606136
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04633, KAKENHI-PROJECT-26670056
[Journal Article] Synthetic Receptor Molecules for Selective Fluorescent Detection of 8-oxo-dGTP inAqueous Media2016
- Author(s)
  Fuchi Yasufumi, Fukuda Takashi, Sasaki Shigeki
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 14 Issue: 33 Pages: 7949-7955
- DOI
  10.1039/c6ob01485b
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04633, KAKENHI-PROJECT-15K18831
[Journal Article] 最新のトピックス「化学反応性を獲得した核酸－酸化的に化学修飾されたグアノシン誘導体」2016
- Author(s)
  渕　靖史、佐々木　茂貴
- Journal Title
  
  月刊「化学」－化学同人
  
  Volume: 71 Pages: 70-71
- Data Source
  KAKENHI-PROJECT-15K18831
[Journal Article] Recognition and detection of 8-oxo-rG in RNA using the DNA/OMeRNAchimera probes containing fluorescent adenosine-diazaphenoxazine analogue2016
- Author(s)
  Koga Yohie, Taniguchi Yosuke, Kikukawa Yoshiya, Sasaki Shigeki
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 24 Issue: 6 Pages: 1308-1313
- DOI
  10.1016/j.bmc.2016.02.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04633
[Journal Article] DNA cleavage at the AP site via β-elimination mediated by the AP site-binding ligands2016
- Author(s)
  Yukiko S. Abe, Shigeki Sasaki
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 24 Issue: 4 Pages: 910-914
- DOI
  10.1016/j.bmc.2016.01.016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860079, KAKENHI-PROJECT-15H04633
[Journal Article] Enhancement of TFO Triplex Formation by Conjugation with Pyrene via Click Chemistry2015
- Author(s)
 Taniguchi Y, Tomizaki A, Matsueda N, Okamura H, Sasaki S
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 63 Issue: 11 Pages: 920-926
- DOI
 10.1248/cpb.c15-00570
- NAID
 130005105722
- ISSN
 0009-2363, 1347-5223
- Language
 English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
 KAKENHI-PROJECT-26670056, KAKENHI-PROJECT-15H04633, KAKENHI-PROJECT-24689006
[Journal Article] New NitroG-Grasp Molecules with Enhanced Capture Reactivity for 8-Nitroguanosine in the Aqueous Media2015
- Author(s)
  Fuchi Y. and Sasaki S.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 63 Issue: 11 Pages: 913-919
- DOI
  10.1248/cpb.c15-00550
- NAID
  130005105721
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18831, KAKENHI-PROJECT-26670004
[Journal Article] Site-specific modification of the 6-amino group ofadenosine in RNA by an inter-strand functionality-transfer reaction using an S-functionalized-4-thiothymidine2015
- Author(s)
  Oshiro I. Jitsuzaki D. Onizuka K. Nishimoto A. Taniguchi Y. and Sasaki S
- Journal Title
  
  ChemBioChem,
  
  Volume: 16 Issue: 8 Pages: 1190-1198
- DOI
  10.1002/cbic.201500084
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04633, KAKENHI-PROJECT-15J03430
[Journal Article] Development of New 1,3-Diazaphenoxazine Derivatives (ThioG-Grasp) to CovalentlyCapture 8-Thioguanosine2015
- Author(s)
  Fuchi. Y, Obayashi. H and Sasaki. S
- Journal Title
  
  Molecules
  
  Volume: 20 Issue: 1 Pages: 1078-1087
- DOI
  10.3390/molecules20011078
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J04273, KAKENHI-PROJECT-15K18831, KAKENHI-PROJECT-26670004
[Journal Article] Stabilization of the i-motif structure by the intra-strand cross-link formation.2015
- Author(s)
  K. Kikuta, H. Piao, J. Brazier, ,Y. Taniguchi, K.Onizuka, F. Nagatsugi, S. Sasaki
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 25 Issue: 16 Pages: 3307-3310
- DOI
  10.1016/j.bmcl.2015.05.064
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05838, KAKENHI-PUBLICLY-26102710, KAKENHI-PROJECT-15H04633, KAKENHI-PROJECT-25288073
[Journal Article] Development of New 1,3-Diazaphenoxazine Derivatives (ThioG-Grasp) to Covalently Capture 8-Thioguanosine2015
- Author(s)
  Yasufumi Fuchi, Hideto Obayashi and Shigeki Sasaki
- Journal Title
  
  Molecules
  
  Volume: 20 Pages: 1078-1087
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670004
[Journal Article] Strong Positive Cooperativity in Binding to the A3T3 Repeat by Hoechst 33258Derivatives Attaching the Quinoline Units at the end of a Branched Linker2015
- Author(s)
  Koda H., Brazier J., Onishi I., Sasaki S.
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 23 Issue: 15 Pages: 4583-4590
- DOI
  10.1016/j.bmc.2015.05.056
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04633
[Journal Article] Identification of the5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highlyselective PDE4B inhibitors Bioorg2014
- Author(s)
  Goto T., Shiina A., Murata T., Tomii M., YamazakiT., Yoshida K., Yoshino T., Suzuki O., Sogawa Y., Mizukami K., Takagi N.,Yoshitomi T., Etori M., Tsuchida H., Mikkaichi T., Nakao N., Takahashi M., Takahashi H, Sasaki S.
- Journal Title
  
  Med. Chem. Lett.
  
  Volume: 24(3) Issue: 3 Pages: 893-899
- DOI
  10.1016/j.bmcl.2013.12.076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002
[Journal Article] 2,6-Diaminopurine nucleoside derivative of 9-ethyloxy-2-oxo-1,3-diazaphenoxazine(2-amino-Adap) for recognition of 8-oxo-dG in DNA2014
- Author(s)
  Taniguchi Y., Fukabori K., Kikukawa Y., Koga Y and Sasaki S.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22(5) Issue: 5 Pages: 1634-1641
- DOI
  10.1016/j.bmc.2014.01.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24659047
[Journal Article] A nanocarrier system for the delivery of nucleic acids targeted to a pancreatic beta cell line2014
- Author(s)
  Yamada Y., Tabata M., Yasuzaki Y., Nomura M., Shibata A., Ibayashi Y., Taniguchi Y., Sasaki S., Harashima H.
- Journal Title
  
  Biomaterials
  
  Volume: 35 Issue: 24 Pages: 6430-6438
- DOI
  10.1016/j.biomaterials.2014.04.017
- NAID
  120005512023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-26461383
[Journal Article] Efficient Covalent Capture of 8-Nitroguanosine via a Multiple Hydrogen-Bonded Complex2014
- Author(s)
  Fuchi. Y and Sasaki. S
- Journal Title
  
  Organic Letters
  
  Volume: 16 Issue: 6 Pages: 1760-1763
- DOI
  10.1021/ol500452r
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J04273, KAKENHI-PROJECT-24659008, KAKENHI-PROJECT-26670004
[Journal Article] Synthesis of 8-halogenated-7-deaza-2'-deoxyguanosine as an8-oxo-2'-deoxyguanosine analogue and evaluation of its base pairing properties2014
- Author(s)
  Yizhen Y., Taniguchi Y. and Sasaki S.
- Journal Title
  
  Tetrahedron
  
  Volume: 70(11) Issue: 11 Pages: 2040-2047
- DOI
  10.1016/j.tet.2014.01.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002
[Journal Article] N-(Guanidinoethyl)-2'-deoxy-5-methylisocytidine exhibits selective recognition of a CG interrupting site for the formation of anti-parallel triplexes2013
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi and Shigeki Sasaki
- Journal Title
  
  Organic and Biomolecular Chemistry
  
  Volume: 11 Issue: 23 Pages: 3918-3924
- DOI
  10.1039/c3ob40472b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J04516, KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24689006
[Journal Article] Identification of the fused bicyclic4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors.2013
- Author(s)
  Goto T., Shiina A., Yoshino T., Mizukami K.,Hirahara K., Suzuki O., Sogawa Y., Takahashi T., Mikkaichi T., Nakao N., TakahashiM., Hasegawa M. and Sasaki S.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23(11) Issue: 11 Pages: 3325-3328
- DOI
  10.1016/j.bmcl.2013.03.104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002
[Journal Article] Synthesis of 8-oxoguanosine phosphoramidite and its incorporation into oligoribonucleotides2013
- Author(s)
  Taniguchi Y., Koga Y., Shigeki S.
- Journal Title
  
  Current Protocols in Nucleic Acid Chemistry
  
  Volume: UNIT4.58 Issue: 1
- DOI
  10.1002/0471142700.nc0458s56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24659047
[Journal Article] Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidinederivatives as novel and potent PDE4 inhibitors2013
- Author(s)
  Goto T., Shiina A., Yoshino T., Mizukami K.,Hirahara K., Suzuki O., Sogawa Y., Takahashi T., Mikkaichi T., Nakao N.,Takahashi M., Hasegawa M. and Sasaki S.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 (22) Issue: 22 Pages: 7025-7037
- DOI
  10.1016/j.bmc.2013.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002
[Journal Article] Synthesis of the Oligoribonucleotides Incorporating 8-Oxo-guanosine and Evaluation of their Base Pairing Properties2013
- Author(s)
  Koga Y., Taniguchi Y and Sasaki S.
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 32(3) Issue: 3 Pages: 124-136
- DOI
  10.1080/15257770.2013.767461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24659047
[Journal Article] 4-Vinyl-Substituted Pyrimidine Nucleosides Exhibit the Efficient and SelectiveFormation of Interstrand Cross-Links with RNA and duplex DNA2013
- Author(s)
  Nishimoto, A., Jitsuzaki, D., Onizuka, K., Taniguchi, Y., Nagatsugi, F. and Sasaki, S
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 41 Issue: 13 Pages: 6774-6781
- DOI
  10.1093/nar/gkt197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PUBLICLY-24102508, KAKENHI-PROJECT-25288073
[Journal Article] B-Z Transition of (dA-T)n Duplex Induced by Spermine Porphyrin-Conjugate via anIntermediate DNA Conformation2013
- Author(s)
  Sasaki H. and Sasaki S.
- Journal Title
  
  Chem. Comm.
  
  Volume: 49(79) Issue: 79 Pages: 9024-9026
- DOI
  10.1039/c3cc45213a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002
[Journal Article] Synthesis of 1'-phenyl-2-OMe ribose analogues connecting the thymine base at the 1' position through a flexible linker for the formation of a stable anti-parallele triplex DNA2013
- Author(s)
  Taniguchi Y., Okamura H., Fujino N., Sasaki S.
- Journal Title
  
  Tetrahedron
  
  Volume: 69(2) Issue: 2 Pages: 600-606
- DOI
  10.1016/j.tet.2012.11.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24689006
[Journal Article] Enantioselective Binding of Chiral 1,14-Dimethyl[5]Helicene-spermine Ligands with B- and Z-DNA2013
- Author(s)
  Tsuji G,, Kawakami K and Sasaki S.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 (19) Issue: 19 Pages: 6063-6068
- DOI
  10.1016/j.bmc.2013.07.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002
[Journal Article] An efficient antigene activity and antiproliferative effect by targeting the Bcl-2 or survivin gene with triplex forming oligonucleotides containing a W-shaped nucleoside analogue (WNA-βT)2012
- Author(s)
  Taniguchi, Y. and Sasaki, S.
- Journal Title
  
  Org. Biomol. Chem
  
  Volume: 10 Issue: 41 Pages: 8336-8341
- DOI
  10.1039/c2ob26431e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24689006
[Journal Article] Synthesis and binding properties of new selective ligands for the nucleobase opposite the AP site2012
- Author(s)
  Abe Y., Nakagawa O., Yamaguchi R., Sasaki S.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 20(11) Issue: 11 Pages: 3470-3479
- DOI
  10.1016/j.bmc.2012.04.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002
[Journal Article] An efficient and simple method for site-selective modification of O^6-methyl-2'-deoxyguanosine in DNA2012
- Author(s)
  Kazumitsu Onizuka, Takamasa Nishioka, Zhichun Li, Daichi Jitsuzaki, Yosuke Taniguchi, Shigeki Sasaki
- Journal Title
  
  Chem. Commun
  
  Volume: 48 Issue: 33 Pages: 3969-3971
- DOI
  10.1039/c2cc17621a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04012, KAKENHI-PROJECT-21229002
[Journal Article] Properties of Oligonucleotidewith Phenyl-Substituted Carbocyclic Nucleoside Analogues for the Formation ofDuplex and Triplex DNA2012
- Author(s)
  Nasr T, Taniguchi Y., Takaki T., Okamura H., Sasaki S.
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids,
  
  Volume: 31(12) Issue: 12 Pages: 8441-860
- DOI
  10.1080/15257770.2012.737970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24689006
[Journal Article] Efficient DNA strand displacement by a W-shaped nucleoside analogue (WNA-T) containing an ortho-methyl-substituted phenyl ring2012
- Author(s)
  Aoki E., Taniguchi Y., Wada Y., Sasaki S
- Journal Title
  
  ChemBioChem,
  
  Volume: 13(8) Issue: 8 Pages: 1152-1160
- DOI
  10.1002/cbic.201200066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24689006
[Journal Article] Adenosine-1,3-diazaphenoxazine Derivative for Selective Base Pair Formation with 8-Oxo-2'-deoxyguanosine in DNA2011
- Author(s)
  Taniguchi, Y, Kawaguchi, R, Sasaki, S.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 133 Issue: 19 Pages: 7272-7275
- DOI
  10.1021/ja200327u
- Data Source
  KAKENHI-PROJECT-21229002
[Journal Article] The oligodeoxynucleotide probes for the site-specific modification of RNA2011
- Author(s)
  Shigeki Sasaki, Kazumitsu Onizuka, Yosuke Taniguchi
- Journal Title
  
  Chemical Society Reviews
  
  Volume: 40 Issue: 12 Pages: 5698-5706
- DOI
  10.1039/c1cs15066a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04012, KAKENHI-PROJECT-21229002
[Journal Article] Activation and Alteration of Base Selectivity by Metal Cations in the Functionality-Transfer Reaction for RNA Modification2010
- Author(s)
  Onizuka, K.., Taniguchi, Y., Sasaki, S.
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 21 Issue: 8 Pages: 1508-1512
- DOI
  10.1021/bc100131j
- Data Source
  KAKENHI-PROJECT-21229002
[Journal Article] The Spermine-Bisaryl Conjugate as a Potent Inducer for the B to Z-DNA Transition2010
- Author(s)
  Doi I., Tsuji G., Kawakami K., Nakagawa 0., Taniguchi Y., Sasaki S.
- Journal Title
  
  Chem. Eur. J
  
  Volume: 16 Pages: 11993-11999
- Data Source
  KAKENHI-PROJECT-22659004
[Journal Article] A New Usage of Functionalized Oligodeoxynucleotide Probe for Site-SpecificModification of a Guanine Base within RNA2010
- Author(s)
  Onizuka K, Taniguchi Y., Sasaki S.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 38 Issue: 5 Pages: 1760-1766
- DOI
  10.1093/nar/gkp930
- Data Source
  KAKENHI-PROJECT-21229002
[Journal Article] Site-specific covalent modification of nucleic acids guided by functionality-transfer oligodeoxynucleotides2009
- Author(s)
  Onizuka K, Taniguchi Y., Sasaki S.
- Journal Title
  
  Bioconjugate Chem. 20
  
  Pages: 799-803
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Selective Fluorescence Quenching of the 8-OxoG-clamp by 8-Oxodeoxyguanosine in ODN2009
- Author(s)
  Nasr T, Li Z., Nakagawa O., Taniguchi Y., Ono S., Sasaki S.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 19
  
  Pages: 727-730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Selective Fluorescence Quenching of the 8-OxoG-clamp by 8-Oxodeoxyguanosine in ODN, Bioorg2009
- Author(s)
  Nasr T., Li Z., Nakagawa O., Taniguchi Y., Ono S., Sasaki S.
- Journal Title
  
  Med. Chem. Lett. 19
  
  Pages: 727-730
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Incorporation of inducible nucleotide analog into DNA by DNA polymerases2009
- Author(s)
  Ali M. M., Imoto S., Li Y., Sasaki S. Nagatsugi F.
- Journal Title
  
  Bioorg. Med. Chem. 17
  
  Pages: 2859-2863
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Stereoselective synthesis of(t)-2-deoxyolivin based on cycloaddition reaction between the homophthalic anhydride and the chiral cyclohexenone derivative2008
- Author(s)
  Haruta Y., Onizuka K., Watanabe K., Kono K., Nohara A., Kubota K., Imoto S., Sasaki S.
- Journal Title
  
  Tetrahedron 64
  
  Pages: 7211-7218
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Site-specific modification by functionality-transfer oligonucleotide with the photo-inducible reactivity.2008
- Author(s)
  Onizuka K, Taniguchi Y., Nishioka X, Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 367-368
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Synthesis of p-amino-WNA derivatives to enhance the stability of the anti-parallel triplex2008
- Author(s)
  Taniguchi Y., Togo M., Aoki E., Uchida Y., Sasaki S.
- Journal Title
  
  Tetrahedron 64
  
  Pages: 7164-7170
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Formation of a stable triplex incorporating a CG interrupting site by a new WNA derivative containing 3-aminopyrazole as a nucleobase.2008
- Author(s)
  Uchida Y., Taniguchi Y., Aoki E., Togo M., Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 137-138
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Synthesis and Evaluation of the Luciferase-Oligodeoxynucleotide for the Sequencse-Selective Detection of Nucleic Acids2008
- Author(s)
  Nagatsugi F., Nakahara R., Inoue K., Sasaki S.
- Journal Title
  
  Arch. Pharm. Chem. Life Sci. 341
  
  Pages: 562-567
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Synthesis and Evaluation of the Luciferase-Oligodeoxynucleotide for the Sequence-Selective Detection of Nucleic Acids2008
- Author(s)
  Nagatsugi F, Nakahara R., Inoue K., Sasaki S
- Journal Title
  
  Arch. Pharm. Chem. Life Sci 341
  
  Pages: 562-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Stereoselective synthesis of (+)-2-deoxyolivin based on cycloaddition reaction between the homophthalic anhydride and the chiral cyclohexenone derivative2008
- Author(s)
  Haruta Y, Onizuka K., Watanabe K., Kono K., Nohara A., Kubota K., Imoto S., Sasaki S.
- Journal Title
  
  Tetrahedron 64
  
  Pages: 7211-7218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Binding of two bis-bipyridine minor groove binders to a DNA template in the presence of Cu^<2+> ion.2008
- Author(s)
 Brazier, J. A., Onishi I., Sasaki S.
- Journal Title
 
 Nucleic Acids Symp. Ser. 52
 
 Pages: 107-108
- Data Source
 KAKENHI-PROJECT-17209001
[Journal Article] Synthesis of new nucleosides analogue connecting 2-amino-6-vinylpurine to the 2'-deoxyribose skeleton via the methylene linker.2008
- Author(s)
  Kurose Y., Taniguchi, Y., Nagatsugi R, Sasaki S.
- Journal Title
  
  Nucleic Acids Symp., Ser. 52
  
  Pages: 43-44
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Binding of two bis-bipyridine minor groove binders to a DNA template in the presence of Cu2+ion2008
- Author(s)
  Brazier, J. A., Onishi I., Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 107-108
- Data Source
  KAKENHI-PROJECT-20659003
[Journal Article] Specific Fluorescent Probe for 8-Oxoguanosine2007
- Author(s)
  Nakagawa O., Ono S., Li Z., Tsujimoto A., Sasaki S.
- Journal Title
  
  Angewandte Chemie International Edition 46,No.24
  
  Pages: 4500-4503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] A New Copper(II)Complex as an Efficient Catalyst of Luminol Chemiluminescence2007
- Author(s)
  Uzu T., Sasaki S.
- Journal Title
  
  Organic Letters 9, No.21
  
  Pages: 4383-4386
- NAID
  130006996108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659004
[Journal Article] Equilibrium shift by target DNA substrates for determination of DNA binding ligands2007
- Author(s)
  Tsujita S., Tanada M., Kataoka T., Sasaki S.
- Journal Title
  
  Bioorganic&Medicinal Chemistry Letters 17
  
  Pages: 68-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659004
[Journal Article] Specific Fluorescent Probe for 8-Oxoguanosine2007
- Author(s)
  Nakagawa O., Ono S., Li Z., Tsujimoto A., Sasaki S.
- Journal Title
  
  Angewandte Chemie International Edition 46, No.24
  
  Pages: 4500-4503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659004
[Journal Article] Equilibrium shift by target DNA substrates for determination of DNA binding ligands,2007
- Author(s)
  Tsujita S., Tanada M., Kataoka T., Sasaki S.
- Journal Title
  
  Bioorg, Med. Chem. Lett., 17
  
  Pages: 68-72
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Specific Fluorescent Probe for 8-Oxoguanosine2007
- Author(s)
  Nakagawa O., Ono S., Li Z., Tsujimoto A., Sasaki S.
- Journal Title
  
  Angew. Chem. Int. Ed 46 (In press)
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Equilibrium shift by target DNA substrates for determination of DNA binding ligands2007
- Author(s)
  Tsujita S., Tanada M., Kataoka T., Sasaki S.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 17
  
  Pages: 68-72
- Data Source
  KAKENHI-PROJECT-18659004
[Journal Article] Specific Fluorescent Probe for 8-Oxoguanosine2007
- Author(s)
  Nakagawa O., Ono S., Li Z., Tsujimoto A., Sasaki S.
- Journal Title
  
  Angew. Chem. Int. Ed 46(In press)
- Data Source
  KAKENHI-PROJECT-18659004
[Journal Article] Equilibrium shift by target DNA substrates for determinationr of DNA binding liands2007
- Author(s)
  Tsujita S., Tanada M., Kataoka T., Sasaki S.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 17
  
  Pages: 68-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] A New Copper(II)Complex as an Efficient Catalyst of Luminol Chemiluminescence2007
- Author(s)
  Uzu T., Sasaki S.
- Journal Title
  
  Organic Letters 9,No.21
  
  Pages: 4383-4386
- NAID
  130006996108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Cu^<2+>-Mediated Assembly of the Minor Groove Binders on the DNA Template with Sequence Selectivity2006
- Author(s)
 Tanada M., Tsujita S., Kataoka T., Sasaki S.
- Journal Title
 
 Organic Lett. 8
 
 Pages: 2475-2478
- Data Source
 KAKENHI-PROJECT-18659004
[Journal Article] Recognition of DNA with assembly of minor groove binders mediated by metal complexation2006
- Author(s)
  Kataoka T., Tanada M., Onishi I., Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 50
  
  Pages: 161-162
- Data Source
  KAKENHI-PROJECT-18659004
[Journal Article] Intracelullar Ability of an Inducible Alkylation System to Exhibit Antisense Effects with Greater Potency and Selectivity2006
- Author(s)
  Ali M.M., Oishi M., Nagatsugi F., Mori K., Nagasaki Y., Kataoka K., Sasaki S
- Journal Title
  
  Angew.Chem.Int.Ed (In press)
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Effects of Halogenated WNA Derivatives on Sequence Dependency for Expansion of Recognition Sequences in the Non-Natural Type Triplexes2006
- Author(s)
  Taniguchi Y., Nakamura A., Senko Y., Nagatsuki F., Sasaki S
- Journal Title
  
  J.Org.Chem (In press)
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Novel drug releasing system triggered by hybridization with target sequence,2006
- Author(s)
  Nakayama S., Nagatsugi F., Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser 50
  
  Pages: 143-144
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Effects of the modified aromatic ring of WNA on stability of triplex DNA2006
- Author(s)
  Aoki E., Taniguchi Y., Togo M., Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 50
  
  Pages: 185-186
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Cu^<2+>-Mediated Assembly of the Minor Groove Binders on the DNA Template with Sequence Selectivity2006
- Author(s)
 Tanada M., Tsujita S., Kataoka T., Sasaki S.
- Journal Title
 
 Organic Lett., 8
 
 Pages: 2475-2478
- Data Source
 KAKENHI-PROJECT-17209001
[Journal Article] Novel drug releasing system triggered by hybridization with target sequence2006
- Author(s)
  Nakayama S., Nagatsugi F., Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser 50
  
  Pages: 143-144
- Data Source
  KAKENHI-PROJECT-18659004
[Journal Article] Recognition of DNA with assembly of minor groove binders mediated by metal complexation,2006
- Author(s)
  Kataoka T., Tanada M., Onishi I., Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 50
  
  Pages: 161-162
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Application of 2-Amino-6-Vinylpurine as an Efficient Agent for Conjugation of Oligonucleotides2006
- Author(s)
  Ali M.M., Nagatsugi F., Sasaki S., Nakahara R., Maeda M
- Journal Title
  
  Nucleosides, Nucleotides, and Nucleic Acids 25
  
  Pages: 159-169
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Effects of the modified aromatic ring of WNA on stability of triplex DNA2006
- Author(s)
  Aoki E., Taniguchi Y., Togo M., Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 50
  
  Pages: 185-186
- Data Source
  KAKENHI-PROJECT-18659004
[Journal Article] Substituent Effects on the In situ Activation of the Double Activated Cross-linking Reaction2005
- Author(s)
  F.Nagatsugi, S.Mori, Md.Monsur Ali, Y.Ogata, S.Sasaki
- Journal Title
  
  Nucleic Acids Symp.Ser 49
  
  Pages: 175-176
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Smart Polyion Complex Micelles for Targeted Intracellular Delivery of PEG vlated Antisense Oligonucleotide with Acid-Labile Linkage2005
- Author(s)
  M.Oishi, F.Nagatsugi, S.Sasaki, Y.Nagasaki, K.Kataoka
- Journal Title
  
  ChemBioChem 6
  
  Pages: 1-6
- Data Source
  KAKENHI-PROJECT-15659004
[Journal Article] Hybridization-Promoted and Cytidine-Selective Activation for Cross-Linking with the Use of 2-Amino-6-Vinylpurine Derivatives2005
- Author(s)
  T.Kawasaki, F.Nagatsugi, Md.M.Ali, M.Maeda, K.Sugiyama, K.Hori, S.Sasaki
- Journal Title
  
  J.Org.Chem. 70(1)
  
  Pages: 14-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Smart Polyion Complex Micelles for Targeted Intracellular Delivery of PEGYlated Antisense Oligonucleotide with Acid-Labile Linkage2005
- Author(s)
  M.Oishi, F.Nagatsugi, S.Sasaki, Y.Nagasaki, K.Kataoka
- Journal Title
  
  ChemBioChem 6
  
  Pages: 1-6
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide: Polylon complex (PIC) micelles based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate2005
- Author(s)
  M.Oishi, T.Hayama, Y.Akiyama, S.Takae, A.Harada, T.Yarnasaki, F.Nagatsugi, S.Sasaki, Y.Nagasaki, K.Kataoka
- Journal Title
  
  Biomacromolecules 6
  
  Pages: 2449-2454
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Smart Polyion Complex Micelles for Targeted Intracellular Delivery of PEGylated Antisense Oligonucleotide with Acid-Labile Linkage2005
- Author(s)
  Oishi, M., F.Nagatsugi, Sasaki, S, Nagasaki, Y., Kataoka, K
- Journal Title
  
  ChemBioChem 6
  
  Pages: 718-725
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Development of efficient packaging method of oligodeoxynucleotides by a condensed nano particle in lipid envelope structur2005
- Author(s)
  Y.Yamada, K.Kogure, Y.Nakamura, K.Inoue, H.Akita, F.Nagatsugi, S.Sasaki, T.Suhara, H.Harashima
- Journal Title
  
  Biol.Pharm.Bull 28
  
  Pages: 1939-1942
- NAID
  110003666368
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Smart Polyion Complex Micelles for Targeted Intracellular Delivery of PEGylated Antisense Oligonucleotide with Acid-Labile Linkage2005
- Author(s)
  M.Oishi, F.Nagatsugi, S.Sasaki, Y.Nagasaki, K.Kataoka
- Journal Title
  
  ChemBioChem 6
  
  Pages: 718-725
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Hybridization-Promoted and Cytidine-Selective Activation for Cross-Linking with the Use of 2-Amino-6-Vinylpurine Derivatives2005
- Author(s)
  Kawasaki, T., Nagatsugi, F.Md.Monsur Ali, Maeda, M., Sugiyama, K., Hori, K., Sasaki, S
- Journal Title
  
  J.Org.Chem 70
  
  Pages: 14-23
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Design of highly efficient and selective transfer reaction of nitrosyl group to dC and d^mC resulting in specific deamination2005
- Author(s)
  Md.Monsur Ali, Nagatsuki F., Nakayama, S., Md.Rowshon Alam, Kawasaki, T., Sasaki S
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acid 24
  
  Pages: 721-724
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Expansion of triplex recognition codes by the use of novel bicyclic nucleoside derivatives (WNA)2005
- Author(s)
  Taniguchi, T.; Nakamura, A.; Senko, Y.; Kodama, K.; Nagatsugi, F.; Sasaki, S.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 24
  
  Pages: 823-827
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Smart Polyion Complex Micelles for Targeted Intracellular Delivery of PEG vlated Antisense Oligonucleotide with Acid-Labile Linkage2005
- Author(s)
  M.Oishi, F.Nagatsugi, S.Sasaki, Y.Nagasaki, K.Kataoka.
- Journal Title
  
  ChemBioChem 6
  
  Pages: 718-725
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] New DNA Binding Ligands as a Model of Chromomycin A32004
- Author(s)
  Imoto, S., Haruta Y., Watababe K., Sasaki S.
- Journal Title
  
  Bioorg.Med.Chem.Lett 14
  
  Pages: 4855-4859
- Data Source
  KAKENHI-PROJECT-15659004
[Journal Article] Selective Formation of Stable Triplexes Including a TA or a CG Interrupting Site with New Bicyclic Nucleoside Analogs (WNA)2004
- Author(s)
  Shigeki Sasaki, Yosuke Taniguchi, Ryo Takahashi, Yusuke Senko, Keiichi Kodama, Fumi Nagatsugi, Minoru Maeda
- Journal Title
  
  J.Amer.Chem.Soc. 126(2)
  
  Pages: 516-528
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Chemical tools for targeted mutagenesis of DNA based on triple helix formation2004
- Author(s)
  Nagatsugi Fumi, Sasaki Sasaki
- Journal Title
  
  Biol Pharm Bull. 27・4
  
  Pages: 463-467
- NAID
  110003608787
- Data Source
  KAKENHI-PROJECT-15659004
[Journal Article] Selective Formation of Stable Triplexes Including a TA or a CG Interrupting Site with New Bicyclic Nucleoside Analogs (WNA)2004
- Author(s)
  Shigeki Sasaki, Yosuke Taniguchi, Ryo Takahashi, Yusuke Senko, Keiichi Kodama, Fumi Nagatsugi, Minoru Maeda
- Journal Title
  
  J.Amer.Chem.Soc., 516-528(2004) 126(2)
  
  Pages: 516-528
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Bipyrrole Derivatives as New DNA-Minor Groove Binders,2004
- Author(s)
  Tanada, Mikimasa, Shibata, Yoshihiro, Maeda, Minoru, Sasaki, Shigeki
- Journal Title
  
  Heterocycles 63(1)
  
  Pages: 29-39
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Sequence- and Base-Specific Delivery of Nitric Oxide to Cytidine and 5-Methylcytidine Leading to Efficient Deamination2004
- Author(s)
  Md.M.Ali, Md.R.Alam, T.Kawasaki, S.Nakayama, F.Nagatsugi, S.Sasaki
- Journal Title
  
  J.Am.Chem.Soc. 126
  
  Pages: 8864-8865
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Chemical tools for targeted mutagenesis of DNA based on triple helix formation2004
- Author(s)
  Nagatsugi Fumi, Shigeki Sasaki
- Journal Title
  
  Biol Pharm Bull. 27
  
  Pages: 4463-4467
- NAID
  110003608787
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Bipyrrole Derivatives as New DNA-Minor Groove Binders2004
- Author(s)
  Tanada, Mikimasa, Shibata, Yoshihiro, Maeda, Minoru, Sasaki, Shigeki
- Journal Title
  
  Heterocycles 63(1)
  
  Pages: 29-39
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Synthesis of 11C-Labeled Bis(phenylalkyl)amine and Their in Vitro and in Vivo Binding Properties in Rodent and Monkey Brains2004
- Author(s)
  Shigeki SAsaki, Fumie Kurosaki, Terushi Haradahira, Fumihiko Yamamoto, Jun Maeda, Takesh Okauchi, Kazatoshi Suzuki, Tetsuya
- Journal Title
  
  Biol.Pharm.Bull. 27(4)
  
  Pages: 531-537
- NAID
  110003608800
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Synthesis of 11C-Labeled Bis(phenylalkyl)amine and Their in Vitro and in Vivo Binding Properties in Rodent and Monkey Brains2004
- Author(s)
  Shigeki Sasaki, Fumie Kurosaki, Terushi Haradahira, Fumihiko Yamamoto, Jun Maeda, Takesh Okauchi, Kazatoshi Suzuki, Tetsuya
- Journal Title
  
  Biol.Pharm.Bull. 27(4)
  
  Pages: 531-537
- NAID
  110003608800
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Chemical tools for targeted mutagenesis of DNA based on triple helix formation2004
- Author(s)
  Nagatsugi Fumi, Sasaki Sasaki
- Journal Title
  
  Biol Pharm Bull. 27・4
  
  Pages: 463-467
- NAID
  110003608787
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] New DNA Binding Ligands as a Model of Chromomycin A32004
- Author(s)
  Imoto S., Haruta Y., Watanabe K., Sasaki S.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14
  
  Pages: 4855-4859
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Synthesis of 11C-Labeled Bis(phenylalyl)amine and Their in Vitro and in Vivo Binding Properties in Rodent and Monkey Brains2004
- Author(s)
  Shigeki Sasaki, Fumie Kurosaki, Terushi Haradahira, Fumihiko Yamamoto, Jun Maeda, Takesh Okauchik Kazatoshi Suzuki, Tetsuya
- Journal Title
  
  Biol.Pharm.Bull 27(4)
  
  Pages: 531-537
- Data Source
  KAKENHI-PROJECT-15659004
[Journal Article] Synthesis of 11C-Labeled Bis(phenylalkyl)amine and Their in Vitro and in Vivo Binding Properties in Rodent and Monkey Brains2004
- Author(s)
  Shigeki Sasaki, Fumie Kurosaki, Terushi Haradahira, Fumihiko Yamamoto, Jun Maeda, Takesh Okauchi, Kazatoshi Suzuki, Tetsuya
- Journal Title
  
  Biol.Pharm.Bull 27(4)
  
  Pages: 531-537
- NAID
  110003608800
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] New DNA Binding Ligands as a Model of Chromomycin A32004
- Author(s)
  Imoto S., Haruta Y., Watanabe K., Sasaki S.
- Journal Title
  
  Bioorg.Med.Chem. Lett. 14
  
  Pages: 4855-4859
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Structural activity relationship between Salmonella-mutagenicity and nitro-orientation of nitroazaphenanthrenes,2003
- Author(s)
  Hiroshi Tokiwa, Nobuyuki Sera, Kiyoshi Fukuhara, Hideo Utsumi, Shigeki Sasaki, Naoki Miyata
- Journal Title
  
  Chemico-Biological Interactions 146(1)
  
  Pages: 19-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Cross-linking reactions via synchronous activation mechanism triggered by duplex DNA formation2003
- Author(s)
  Shigeki Sasaki
- Journal Title
  
  Genome Chemistry Chapter 2-6 (eds, M.Sekine and I.Saito) (Koudansha Scientific) (Tokyo)
  
  Pages: 89-100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] pH-responsive oligodeoxynucleotide (ODN)-poly(ethylene glycol) conjugate through acid-labile beta-thiopropionate linkage : preparation and polyion complex micelle formation,2003
- Author(s)
  Oishi M, Sasaki S, Nagasaki Y, Kataoka K.
- Journal Title
  
  Biomacromolecules 4(5)
  
  Pages: 1426-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] pH-responsive oligodeoxynucleotide (ODN)-poly(ethylene glycol) conjugate through acid-labile beta-thiopropionate linkage : preparation and polyion complex micelle formation2003
- Author(s)
  Oishi M, Sasaki S, Nagasaki Y, Kataoka K.
- Journal Title
  
  Biomacromolecules 4(5)
  
  Pages: 1426-1432
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Site-Specific Mutagenesis by Triple-Helix Forming Oligonucleotides Containing a Reactive Nucleoside Analogue.2003
- Author(s)
  Nagatsugi F., Sasaki S., Miller P.S., Seidman M.M.
- Journal Title
  
  Nucleic Acids Res. 31・6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Structural activity relationship between Salmonella-mutagenicity and nitro-orientation of nitroazaphenanthrenes,2003
- Author(s)
  Hiroshi Tokiwa, Nobuyuki Sera, Kiyoshi Fukuhara, Hideo Utsumi, Shigeki Sasaki, Naoki Miyata
- Journal Title
  
  Chemico-Biological Interactions 146
  
  Pages: 19-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Journal Article] Site-Specific Mutagenesis by Triple-Helix Forming Oligonucleotides Containing a Reactive Nucleoside Analogue.2003
- Author(s)
  Nagatsugi F., Sasaki S., Miller P.S., Seidman M.M.
- Journal Title
  
  Nucleic Acids Res. 31
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Patent] 核酸の標識方法2019
- Inventor(s)
  佐々木茂貴、谷口陽祐、原田額郎
- Industrial Property Rights Holder
  佐々木茂貴、谷口陽祐、原田額郎
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18H02558
[Patent] 核酸の標識方法2019
- Inventor(s)
  佐々木茂貴，原田額郎，谷口陽祐
- Industrial Property Rights Holder
  国立大学法人九州大学, 株式会社久留米リサーチ・パーク
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-065888
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18H02558
[Patent] ヌクレオシドアナログ誘導体およびその利用2013
- Inventor(s)
  佐々木茂貴, 谷口陽祐, 河口亮太
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-01
- Overseas
- Data Source
  KAKENHI-PROJECT-21229002
[Patent] DNA及びRNAに対する化学架橋形成のための4-ビニルピリミジンヌクレオシド誘導体2011
- Inventor(s)
  佐々木茂貴, 鬼塚和光, 西本篤史, 谷口陽祐
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2011-08-01
- Data Source
  KAKENHI-PROJECT-21229002
[Patent] 水性検体溶液中の8-オキソグアノシンを高感度で定量検出する方法2011
- Inventor(s)
  佐々木茂貴, 他
- Industrial Property Rights Holder
  九州大学
- Filing Date
  2011-08-24
- Data Source
  KAKENHI-PROJECT-21229002
[Patent] DNA及びRNAに対する化学架橋形成のための4-ビニルピリミジンヌクレオシド誘導体2011
- Inventor(s)
  佐々木茂貴, 他
- Industrial Property Rights Holder
  九州大学
- Filing Date
  2011-08-01
- Data Source
  KAKENHI-PROJECT-21229002
[Patent] 水性検体溶液中の8-オキソグアノシンを定量検出する方法2011
- Inventor(s)
  佐々木茂貴, 中川治, 李志春, 高木厚司, 齋藤幸代
- Industrial Property Rights Holder
  株式会社TASプロジェクト
- Industrial Property Rights Type
  特許
- Filing Date
  2011-03-25
- Data Source
  KAKENHI-PROJECT-21229002
[Patent] 官能基転移核酸を用いる迅速なRNA修飾方法2010
- Inventor(s)
  佐々木茂貴, 他
- Industrial Property Rights Holder
  九州大学
- Industrial Property Number
  2010-202349
- Filing Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21229002
[Patent] 新規ヌクレオシドアナログ及びその利用2010
- Inventor(s)
  佐々木茂貴, 他
- Industrial Property Rights Holder
  九州大学
- Industrial Property Number
  2010-276135
- Filing Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21229002
[Patent] 官能基転移核酸を用いる迅速なRNA修飾方法2010
- Inventor(s)
  佐々木茂貴, 鬼塚和光, 谷口陽祐
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21229002
[Patent] チオヌヌクレオシド-S- ニトロシル誘導体2003
- Inventor(s)
  佐々木茂貴
- Filing Date
  2003-04-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390007
[Presentation] CGGリピート配列への低分子集積によるFMR1遺伝子の転写活性化2024
- Author(s)
  村瀬裕貴、川久保厚佑、塩田倫史、佐々木茂貴
- Organizer
  日本薬学会第143回年会
- Data Source
  KAKENHI-PROJECT-23K21354
[Presentation] CGGリピート関連疾患に対する低分子創薬2024
- Author(s)
  村瀬裕貴、塩田倫史、佐々木茂貴
- Organizer
  日本薬学会第143回年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21354
[Presentation] Study on read-through of premature termination codon by site-specific chemical modification2023
- Author(s)
  Jeongsu Lee, Hirotaka Murase, Norihiro Togo, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  The 50th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21354
[Presentation] Effects of the specific chemical modification of the adenine base of the premature termination codon on the readthrough2023
- Author(s)
  Shigeki Sasaki
- Organizer
  A3RONA 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21354
[Presentation] Effects of the specific chemical modification of the adenine base of the premature termination codon on the readthrough2023
- Author(s)
  Shigeki Sasaki
- Organizer
  The 28th French-Japanese Symposium on Medicinal and Fine Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21354
[Presentation] 遺伝子発現制御に関与するメチル化シトシンを含む二本鎖DNAに対して三本鎖DNA形成を可能にする人工核酸の開発2023
- Author(s)
  納富亮大朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  日本ケミカルバイオロジー学会第17回年会
- Data Source
  KAKENHI-PROJECT-23K21354
[Presentation] Development of a new oligonucleotide agent for site-specific RNA acetylation2023
- Author(s)
  Hirotaka Murase, Jeongsu Lee, Yosuke Taniguchi, Shuhei Imoto, Shigeki Sasaki
- Organizer
  The 50th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21354
[Presentation] mRNAの部位特異的分子修飾による未熟終止コドン(PTC)のリードスルー2023
- Author(s)
  村瀬裕貴、李政洙、谷口陽祐、佐々木茂貴
- Organizer
  核酸医薬学会第8回年会
- Data Source
  KAKENHI-PROJECT-23K21354
[Presentation] CGGリピートRNAの構造変換を誘起する1,3-diazaphenoxazine誘導体の開発2022
- Author(s)
  村瀬裕貴、永次史、佐々木茂貴
- Organizer
  日本薬学会　第１４２年会
- Data Source
  KAKENHI-PROJECT-23K21354
[Presentation] ８－オキソグアノシンのDNA配列中位置検出を目指したデアザプリン人工ヌクレオチドの開発と評価2021
- Author(s)
  長田悠佑、相良委公子、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] CGG-リピートRNA に結合する低分子型G-clamp 誘導体の開発2021
- Author(s)
  村瀬裕貴、永次史、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー学会　第15回年会
- Data Source
  KAKENHI-PROJECT-23K21354
[Presentation] RNAの高次構造変化を誘起する新規低分子リガンドの開発2021
- Author(s)
  村瀬裕貴、永次史、佐々木茂貴
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] γ位修飾8-oxo-dGTPによる酸化損傷修復酵素活性検出法の開発2021
- Author(s)
  丸山健登、石川廉、石卉、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 三本鎖DNA形成領域拡張のための5mCG塩基対認識人工核酸の開発2021
- Author(s)
  納富亮大朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 官能基転移人工核酸によるmRNA部位特異的修飾と翻訳への効果の検討2021
- Author(s)
  都甲典宏、菊田健司、村瀬裕貴、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 酸化損傷塩基の認識能向上を目指したピリミジン骨格を有する人工ヌクレオチドの開発2021
- Author(s)
  桜田喬登、長田悠佑、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] CG塩基対とアンチパラレル型三本鎖DNAを形成するC-ヌクレオシドアナログの開発2020
- Author(s)
  (1)納富亮太朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  日本化学会九州支部秋期研究発表会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 遺伝子を標的とした人工核酸搭載核酸医薬の新展開2020
- Author(s)
  (2)谷口陽祐、佐々木茂貴
- Organizer
  第69回高分子討論会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] リピートDNA配列中の複数連続する結合サイトに協奏的に全サイト結合する低分子リガンドの開2020
- Author(s)
  (4)村瀬裕貴、脇坂元太郎、野口幹晴、Ting Wu、佐々木茂貴
- Organizer
  反応と合成の進歩2020特別企画シンポジウム
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 反応性人工核酸を用いた効率的なRNA糖部2'OH基選択的アセチル化2020
- Author(s)
  宮本奈津、阿部由紀子、北﨑健太郎、高崎隼颯、谷口陽祐、佐々木茂貴
- Organizer
  日本本薬学会第１４０年会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 中性水溶液中で8-nitro-cGMPを効率的に捕捉する_人工ホスト分子の開発2020
- Author(s)
  (5)渕靖史、甲斐亮補、倉田翔、唐澤悟、佐々木茂貴
- Organizer
  反応と合成の進歩2020特別企画シンポジウム
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 反応性核酸を用いた環境応答型solvatochromic蛍光分子の蛋白質への導入と修飾蛋白質の評価2020
- Author(s)
  (3)麻生真理子・金城綾香・田畑香織・阿部由紀子・谷口陽祐・佐々木茂貴
- Organizer
  第14回バイオ関連化学シンポジウム2020
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] RNA部位特異的化学反応核酸医薬動態把握技術への展開2019
- Author(s)
  佐々木茂貴
- Organizer
  日本核酸医薬学会第5回年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] Inducible cross-linking reaction of the oligonucleotide containing the 4-vinylpyrimidin-2-one nucleoside to mRNA and the effect on the translation2019
- Author(s)
  Kenji KIkuta, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  日本核酸医薬学会第５回年会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 反応性人工核酸による中性水溶液中での選択的RNA2'OHアセチル化2019
- Author(s)
  北﨑健太郎、宮本奈津、高崎隼颯、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] DNA/RNAを標的にした選択的認識と効率的反応の研究2019
- Author(s)
  佐々木茂貴
- Organizer
  有機合成化学協会九州山口支部講演会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] Site-selective modification of mRNA and its effect on the translation2019
- Author(s)
  Shigeki Sasaki
- Organizer
  CISNAC2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] チオグアニン-ポリアミン結合体を基にしたAPサイト修復阻害剤の開発2019
- Author(s)
  阿部由紀子、佐々木茂貴
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] Pin-point Chemical Modification of mRNA and its Effect on the Translation2019
- Author(s)
  Gakuro Harada, Kenji Kikuta, Yosuke Taniguchi and Shigeki Sasaki
- Organizer
  The 27th French-Japanese Symposium on Medicinal and Fine CHemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 官能基転移人工核酸によるmRNA部位特異的修飾と翻訳への効果の検討2019
- Author(s)
  菊田健司、都甲典宏、大城郁也、原田額郎、谷口陽祐、佐々木茂貴
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] Chemical Reaction for site-selective modification of RNA and its application to the biological system2019
- Author(s)
  Shigeki Sasaki
- Organizer
  8th Japanese-Sino Symposium on Organic Chemistry for Young Scientists
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] Site-specific and efficient acetylation of the 2'-OH of RNA by the reactive oligonucleotide2019
- Author(s)
  Natsu Miyamoto, Kentaro Kitazaki, Hayate Takasaki, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  第46回国際核酸化学シンポジウム（ISNAC2019）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 人工核酸による効率的なRNA糖部２’OH選択的アセチル化2019
- Author(s)
  宮本奈津、北﨑健太郎、高崎隼颯、谷口陽祐、佐々木茂貴
- Organizer
  第５６回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] DNAとRNAを標的にする新しい核酸創薬アプローチ2019
- Author(s)
  佐々木茂貴
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] Oligonucleotide tools for the site-specific modification of mRNA and application to regulation of translation2018
- Author(s)
  Shigeki Sasaki
- Organizer
  第13 回日仏DDS シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] Intra-strand Cross-link Promotes Formation of i-motif structures2018
- Author(s)
  Kenji KIkuta, Piao Haishun, John Brazier Kazumitsu Onizuka, Fumi Nagatsugi, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  XXIII International Roundtable on Nucleosides, Nucleotides and Nucleic Acids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 官能基転移反応による翻訳系に対する影響評価法の確立2018
- Author(s)
  原田額郎、大城郁也、菊田健司、谷口陽祐、佐々木茂貴
- Organizer
  第4回日本核酸医薬学会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] Application of the Functionality Transfer Oligonucleotide for the Site-Selective Internal Labeling of RNA2018
- Author(s)
  Shigeki Sasaki, Ikuya Oshiro, Takuya, Matsumoto, Gakuro Harada, Yosuke Taniguchi
- Organizer
  XXIII International Roundtable on Nucleosides, Nucleotides and Nucleic Acids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 水中で8-nitoro-cGMPを共有結合捕捉するジアザフェノキサジン誘導体の開発2018
- Author(s)
  渕靖史、甲斐亮補、唐澤悟、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー学会第13回年会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 水中で8-nitro-cGMPを共有結合捕捉する1,3-ジアザフェノキサジン骨格をもつ分子プローブの開発2018
- Author(s)
  甲斐亮補、渕靖史、佐々木茂貴
- Organizer
  第４４回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 人工核酸塩基によるRNAの光アセチル化反応の検討2018
- Author(s)
  菊田健司、Jan BARTA、谷口陽祐、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー学会第13回年会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] Synthesisand Evaluation of Photoactive Nucleic Acid Analogues for RNA Acetylation2018
- Author(s)
  Kenji Kikuta, Jan Barta, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  第45回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] DNAリピート配列への共同的結合能を有する低分子化合物の合成と評価2018
- Author(s)
  脇坂元太郎　村瀬裕貴　野口幹晴　Ting WU　佐々木茂貴
- Organizer
  日本薬学会大１３８年会
- Data Source
  KAKENHI-PROJECT-16K15099
[Presentation] 人工核酸塩基を用いたRNAの光アセチル化反応の検討2018
- Author(s)
  菊田健司、Jan Barta 、谷口陽祐、佐々木茂貴
- Organizer
  第4回日本核酸医薬学会
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 光誘起能をもつRNAアシル化反応の検討2018
- Author(s)
  菊田健司　Jan BARTA　谷口陽祐　佐々木茂貴
- Organizer
  日本薬学会大１３８年会
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 触媒基を搭載した人工核酸による配列特異的なRNA糖部2'OHアセチル化2018
- Author(s)
  北﨑健太郎、高崎隼颯、谷口陽祐、佐々木茂貴
- Organizer
  第４４回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] RNA糖部2'位OH基を配列特異的に修飾する人工核酸の開発2018
- Author(s)
  北﨑健太郎　高崎隼颯　谷口陽祐　佐々木茂貴
- Organizer
  日本薬学会大１３８年会
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Attempt to Design Small Molecular Ligands to Assemble on the Duplex DNA with the Multiple Binding Sites Based on the BindingMode of Chromomycin A32018
- Author(s)
  Shigeki Sasaki
- Organizer
  Asian 3 Roundtable on Nucleic Acids A3RONA 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02558
[Presentation] 「DNA リピート配列を低分子化合物の協同効果により識別する新規戦略の構築2017
- Author(s)
  村瀬裕貴、野口幹晴、佐々木茂貴
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K15099
[Presentation] クロスリンクを RNA 部位特異的に形成する人工核酸の開発と翻訳制御の検討2017
- Author(s)
  菊田健司, 谷口陽祐, 佐々木茂貴
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] RNA糖部2'位のOH基を位置特異的に修飾する人工核酸の開発2017
- Author(s)
  北﨑健太郎　高崎隼颯　谷口陽祐　佐々木茂貴
- Organizer
  第54回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] ゲノム標的化学の展開による機能性分子の創成2017
- Author(s)
  佐々木茂貴
- Organizer
  日本薬学会第１３７年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-25
- Invited
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Evaluation of cooperative binding of the smallmolecule ligands to DNA repeating sequence2017
- Author(s)
  Hirotaka Murase　 Tomoharu Noguchi　 Gentaro Wakisaka　Ting Wu　 Shigeki Sasaki
- Organizer
  The 1st Annual Meeting of Japan Society of Nucleic Acids Chemistry
- Data Source
  KAKENHI-PROJECT-16K15099
[Presentation] 長鎖 mRNA に対する部位特異的化学修飾を利用した翻訳制御の評価2017
- Author(s)
  松本卓也, 大城郁也, 實崎大地, 谷口陽祐, 佐々木茂貴
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 誘起反応性アルキル架橋剤を用いたmRNAのアンチセンス阻害と i-motifの安定化2017
- Author(s)
  菊田健司　朴海順　John Brazier　鬼塚和光　永次史　谷口陽祐　佐々木茂貴
- Organizer
  日本核酸医薬学会第3回年会
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 「リガンド間相互作用によって高リピート DNA 配列選択的に結合する低分子化合物の開発2017
- Author(s)
  野口幹晴、村瀬裕貴、佐々木茂貴
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K15099
[Presentation] 長寿命蛍光による 8-oxo-dGTP 検出を目指したランタノイド錯体の開発2017
- Author(s)
  〇福田　高志、渕　靖史、佐々木　茂貴
- Organizer
  日本薬学会第137年会
- Place of Presentation
  宮城県仙台市
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K18831
[Presentation] リガンド間相互作用によって高リピート配列選択的に結合する低分子化合物の開発2017
- Author(s)
  村瀬裕貴　野口幹晴　脇坂元太郎　Ting Wu　佐々木茂貴
- Organizer
  第34回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-16K15099
[Presentation] An Attempt to Photo-induced RNA Acetylation by Oligonucleotides Containing 1-Acetyl-7-nitroindolines2017
- Author(s)
  Kenji Kikuta　 Jan Barta　 Yosuke Taniguchi　 Shigeki Sasaki
- Organizer
  The 1st Annual Meeting of Japan Society of Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] DNA繰り返し配列への協同的結合能を有する低分子リガンドの開発と評価2017
- Author(s)
  脇坂元太郎　野口幹晴　村瀬裕貴　佐々木茂貴
- Organizer
  第54回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-16K15099
[Presentation] RNA 部位特異的化学修飾能を持つ官能基転移核酸の開発と遺伝情報制御法への応用2017
- Author(s)
  大城郁也, 松本卓也, 實崎大地, 谷口陽祐, 佐々木茂貴
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 糖部 2' 位 OH 基を配列特異的に修飾する人工核酸の開発2017
- Author(s)
  北﨑健太郎　高崎隼颯　谷口陽祐　佐々木茂貴
- Organizer
  第34回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Oligonucleotides incorporating the 4-vinylpyrimidine derivatives to investigate the cross-link formation with mRNA2016
- Author(s)
  Kenji Kikuta, Yosuke Taniguchi and Shigeki Sasaki
- Organizer
  第43回国際核酸化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 「二本鎖DNAリピート配列選択的に結合性を発揮する低分子リガンドの開発2016
- Author(s)
  村瀬裕貴、野口幹晴、佐々木茂貴
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-16K15099
[Presentation] A New Strategy for Regulation of Gene Expression based on the Intelligent Oligonucleotides2016
- Author(s)
  Shigeki Sasaki
- Organizer
  The 8th Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  大阪
- Year and Date
  2016-01-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 水中での8-oxoGTP検出を目的としたジアザフェノキサジン―サイクレン亜鉛錯体の創製2016
- Author(s)
  〇渕　靖史、福田　高志、佐々木　茂貴
- Organizer
  第46回複素環化学討論会
- Place of Presentation
  石川県金沢市
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-15K18831
[Presentation] ゲノム標的化学による創薬研究2016
- Author(s)
  佐々木茂貴
- Organizer
  薬学シンポジウム2016 有機化学の先進的ビジョン
- Place of Presentation
  金沢市
- Invited
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] クロスリンク核酸によるmRNAの化学修飾と翻訳への影響2016
- Author(s)
  菊田健司，谷口陽祐，佐々木茂貴
- Organizer
  第42回反応と合成の進歩シンポジウム
- Place of Presentation
  静岡
- Year and Date
  2016-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Development of pyrimidine nucleoside analogs as inducible cross-linking agents for nucleic acids2016
- Author(s)
  Kenji Kikuta, Yosuke Taniguchi and Shigeki Sasaki
- Organizer
  The 25th French-Japanese Symposium on Medicinal and Fine Chemistry
- Place of Presentation
  東京都多摩市
- Year and Date
  2016-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] DNAリピート配列に選択的かつ協奏的に結合する低分子リガンドの創製2016
- Author(s)
  村瀬裕貴、佐々木茂貴
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] The Functionality Transfer Oligonucleotides for Site-Selective Modification of Cytidine or Adenine2016
- Author(s)
  Shigeki Sasaki, Daichi Jitsuzaki, Ikuya Oshiro, Kazumitsu Onizuka, Atsushi Nishimoto, Yosuke Taniguchi
- Organizer
  XXIIInternational Roundtable on Nucleosides Nucleotides and Nucleic Acids
- Place of Presentation
  Paris
- Year and Date
  2016-07-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Non-natural nucleoside derivatives for selective stabilization of the antiparallel triplex DNA with multiple inversion sites2016
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi andShigeki Sasaki
- Organizer
  The First A3 Roundtable Meeting on Chemical Probe Research Hub
- Place of Presentation
  福岡市
- Year and Date
  2016-09-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 8-oxodGTPを特異的に認識する蛍光性ランタノイド分子の開発2016
- Author(s)
  〇福田　高志、渕　靖史、佐々木　茂貴
- Organizer
  第53回化学関連支部合同九州大会
- Place of Presentation
  福岡県北九州市
- Data Source
  KAKENHI-PROJECT-15K18831
[Presentation] Pinpoint modification of 6-NH2 of the adenine in RNA by the functionality transfer oligonucleotides and its impact on reverse-transcription and translation2016
- Author(s)
  Ikuya Oshiro, Daichi Jitsuzaki, Takuya Matsumoto, Yosuke Taniguchi and Shigeki Sasaki
- Organizer
  第43回国際核酸化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 塩基・部位特異的RNA化学修飾能を持つ官能基転移核酸による遺伝情報制御法の開発2016
- Author(s)
  大城郁也、實崎大地、松本卓也、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Design of the reactive nucleoside analogs and its incorporation into the oligonucleotised for the site-selective chemicalmodification of the 2'-hydroxyl group of RNA2016
- Author(s)
  Hayate Takasaki,Yurie Hadano, Yosuke Taniguchi and Shigeki Sasaki
- Organizer
  第43回国際核酸化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 酸化損傷ヌクレオチド8-oxo-dGTPの特異的検出を目指した亜鉛錯体分子の開発2016
- Author(s)
  〇渕　靖史、佐々木　茂貴
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Place of Presentation
  京都府京都市
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-15K18831
[Presentation] 細胞中検出を目指した8-oxoGTP特異的認識分子の開発2016
- Author(s)
  渕靖史、福田高志、佐々木茂貴
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] 核酸医薬の現状と話題2016
- Author(s)
  佐々木茂貴
- Organizer
  医工学フォーラム
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 長寿命蛍光による8-oxo-dGTP検出を目指したランタノイド錯体の開発2016
- Author(s)
  〇福田　高志、渕　靖史、佐々木　茂貴
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島県鹿児島市
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15K18831
[Presentation] DNA の B-Z 構造遷移に同期しキラル変換する[5]ヘリセンリガンドのシンクロナイズド不斉誘起2016
- Author(s)
  川良健祐、佐々木茂貴
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  金沢市
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] ＲＮＡの２’位水酸基を配列特異的に修飾する人工核酸の開発2016
- Author(s)
  高崎隼颯、羽田野友里恵、谷口陽祐、佐々木茂貴
- Organizer
  第５３回化学関連支部合同九州大会
- Place of Presentation
  北九州市
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 水中の8-oxodG特異的な検出デバイスの開発2016
- Author(s)
  渡部卓磨、渕靖史、佐々木茂貴
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] RNA部位特異的化学修飾能を持つ官能基転移核酸の開発と遺伝情報制御法への展開2016
- Author(s)
  大城郁也，實崎大地，松本卓也，谷口陽祐，佐々木茂貴
- Organizer
  第14回次世代を担う有機化学シンポジウム
- Place of Presentation
  東京都渋谷区
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 自己活性化能をもつピリミジン型クロスリンク核酸の開発2016
- Author(s)
  菊田健司、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 低分子リガンドによるリピート配列の選択的認識2016
- Author(s)
  村瀬裕貴、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Place of Presentation
  京都
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16K15099
[Presentation] 細胞中検出を目指した8-oxoGTP特異的認識分子の開発2016
- Author(s)
  渕靖史、福田高志、佐々木茂貴
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K18831
[Presentation] RNAの2’位水酸基を配列特異的に修飾する人工核酸の開発2016
- Author(s)
  高崎隼颯, 羽田野友里恵, 谷口陽祐, 佐々木茂貴
- Organizer
  第３３回日本薬学会九州支部大会
- Place of Presentation
  鹿児島市
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 金属応答性ピリミジン型機能性核酸を用いたアデニン選択的RNA修飾法の開発2015
- Author(s)
  大城郁也、實崎大地、西本篤史、鬼塚和光、谷口陽祐、佐々木茂貴
- Organizer
  第２５回万有福岡シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Development of 1,3-diazaphenoxazine derivatives (nitroG-Grasp) for selective capture of 8-nitroguanosine2015
- Author(s)
  Yasufumi Fuchi and Shigeki Sasaki
- Organizer
  The 42nd International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  イーグレ姫路（姫路）
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18831
[Presentation] ジアザフェノキサジン環を基本骨格とする８位酸化グアノシン捕捉分子の開発2015
- Author(s)
  渕靖史、大林秀都、佐々木茂貴
- Organizer
  第４１回反応と合成の進歩シンポジウム
- Place of Presentation
  近畿大学（大阪）
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-15K18831
[Presentation] Selective and cooperative binding of small molecular ligands to a GC repetitive site of DNA mediated by multiple complexationwith metal cations2015
- Author(s)
  Hirotaka Murase,　Shigeki Sasaki
- Organizer
  PACIFICHEM2015
- Place of Presentation
  ホノルル
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Development of1,3-diazaphenoxazine derivatives (nitroG-Grasp) for selective capture of8-nitroguanosine2015
- Author(s)
  Yasufumi Fuchi, Shigeki Sasaki
- Organizer
  The 42nd International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  姫路
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] The effect ofintra-strand cross-link formation on the stability of DNA i-motif2015
- Author(s)
  Kenji Kikuta, PiaoHaishun, John Brazier, Kazumitsu Onizuka, Fumi Nagatsugi, Yosuke Taniguchi,Shigeki Sasaki
- Organizer
  第４２回国際核酸化学シンポジウム
- Place of Presentation
  姫路
- Year and Date
  2015-09-23
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Efficient covalent capture of 8-nitroguanosine via a multiple hydrogenbonded complex2015
- Author(s)
  Yasufumi Fuchi, Shigeki Sasaki
- Organizer
  PACIFICHEM2015
- Place of Presentation
  ホノルル
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] 選択的8位酸化グアノシン捕捉モデル分子”Grasp”誘導体の開発2015
- Author(s)
  渕靖史、大林秀都、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  仙台
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] 選択的8位酸化グアノシン捕捉モデル分子“Grasp”誘導体の開発2015
- Author(s)
  渕　靖史、大林　秀都、佐々木　茂貴
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  東北大学（仙台）
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15K18831
[Presentation] リピート配列を標的とした配列選択的集積性リガンドの開発2015
- Author(s)
  村瀬裕貴、佐々木茂貴
- Organizer
  第27回若手研究者のためのセミナー
- Place of Presentation
  福岡
- Year and Date
  2015-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] ＲＮＡの２’位水酸基を修飾する官能基転移核酸の開発2015
- Author(s)
  高崎隼颯、羽田野友里恵、谷口陽祐、佐々木茂貴
- Organizer
  第３２回日本薬学会九州支部大会
- Place of Presentation
  延岡
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Efficient covalent capture of 8-nitroguanosine via a multiple hydrogenbonded complex2015
- Author(s)
  Yasufumi Fuchi and Shigeki Sasaki
- Organizer
  PACIFICHEM 2015
- Place of Presentation
  Hawaii (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18831
[Presentation] 8-oxodGTPを特異的に認識する蛍光性ランタノイド錯体分子の合成と評価2015
- Author(s)
  福田高志、渕靖史、佐々木茂貴
- Organizer
  第３２回日本薬学会九州支部大会
- Place of Presentation
  延岡
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] 多官能化アントラセノン誘導体による繰り返しDNA配列への協奏的結合2015
- Author(s)
  村瀬裕貴、佐々木茂貴
- Organizer
  第４１回反応と合成の進歩シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 鎖内クロスリンク形成によるi-motifの安定化2015
- Author(s)
  菊田健司、朴海順、John Brazier、鬼塚和光、永次史、谷口陽祐、佐々木茂貴
- Organizer
  第９回バイオ関連化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 鎖内クロスリンク反応を用いたi-motifの安定化2015
- Author(s)
  菊田健司、朴海順、John Brazier、鬼塚和光、永次史、谷口陽祐、佐々木茂貴
- Organizer
  第５2回化学関連支部合同九州大会
- Place of Presentation
  北九州市
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] ジアザフェノキサジン環を基本骨格とする８位酸化グアノシン捕捉分子の開発2015
- Author(s)
  渕靖史、大林秀都、佐々木茂貴
- Organizer
  第４１回反応と合成の進歩シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] 水素結合錯体形成を介した効率的な８－チオグアノシン捕捉反応分子の開発2015
- Author(s)
  大林秀都、渕靖史、佐々木茂貴
- Organizer
  第５2回化学関連支部合同九州大会
- Place of Presentation
  北九州
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] 末端構造にキノリンを有するHoechst誘導体による二本鎖DNA繰り返し領域への強い協奏的結合2015
- Author(s)
  江田裕則、John Brazier、佐々木茂貴
- Organizer
  第９回バイオ関連化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 金属応答性ピリミジン型機能性人工核酸を用いた高効率アデニン特異的RNA修飾反応の開発2014
- Author(s)
  大城　郁也, 實崎　大地, 西本　篤史, 鬼塚　和光, 谷口陽祐, 佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] [5]ヘリセンリガンドのキラル平衡及びDNAのB-Z遷移に基づく動的な不斉誘起の検討2014
- Author(s)
  川良　健祐, 辻　厳一郎, 佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] CpGアイランド特異的に結合する人工核酸の開発2014
- Author(s)
  松枝　望, 谷口陽祐, 佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] クロスリンク核酸を導入したDNA　i-motifの安定性の検討2014
- Author(s)
  朴　海順, 秋島　広佑, 實崎　大地, 谷口陽祐, 佐々木茂貴, Brazier JOHN
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] ８-ニトログアノシンに対して特異的な補足分子の開発と捕捉反応の解析2014
- Author(s)
  渕靖史、佐々木茂貴
- Organizer
  日本化学会　第94春季年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-24659008
[Presentation] 水中での8-oxoGのデバイスの開発2014
- Author(s)
  渡部　卓磨, 渕　靖史, 佐々木茂貴
- Organizer
  日本薬学会　第134年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-24659008
[Presentation] 金属錯体形成を基本とした多協同的DNA結合性低分子の開発2014
- Author(s)
  村瀬　裕貴, 佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 水素結合錯体形成を介した8-ニトログアノシンに対する共有結合補足分子の開発2014
- Author(s)
  渕　靖史、佐々木茂貴
- Organizer
  第24回万有福岡シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2014-06-06
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] CG塩基対を安定かつ選択的に認識可能なN²ｰ修飾イソシチジン誘導体の合成と３本鎖形成能の評価2014
- Author(s)
  岡村　秀紀, 谷口陽祐, 佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] ヘキスト誘導体による二本鎖DNA上に存在する繰り返し配列への協奏的集積の評価2014
- Author(s)
  江田　裕則, John BRAZIER, 佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] RNA2'-OH部位特異的な修飾反応の開発2014
- Author(s)
  羽田野　友里恵, 佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 8-oxodG選択性向上を目指したAdap誘導体の開発2014
- Author(s)
  菊川　誉也, 谷口陽祐, 深堀　慶太郎, 佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Synthesis and evaluation of 8-halogenated-7-deaza-2'-deoxyguanosine as 8-oxo-2'-deoxyguanosine analogues2014
- Author(s)
  尹　貽貞, 谷口陽祐, 佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] A New Therapeutic Approach Based on Genome-Targeting Chemistry2014
- Author(s)
  Shigeki Sasaki
- Organizer
  Proceedings of the 11th International Symposium
- Place of Presentation
  Korea
- Invited
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 金属錯体形成を利用したRNA部位特異的化学修飾反応の開発と反応機構解析2014
- Author(s)
  實崎　大地, 鬼塚　和光, 西本　篤史, 谷口陽祐, 佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 水中での8-oxoGの検出デバイスの開発2013
- Author(s)
  渡部卓磨、渕靖史、佐々木茂貴
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎（長崎国際大学）
- Data Source
  KAKENHI-PROJECT-24659008
[Presentation] Sequence specific adenosine modification of RNA by functionality-transfer ODN accelerated by metal cations2013
- Author(s)
  Ikuya Oshiro, Daichi Jitsuzaki, Atsushi Nishimoto, Kazumitsu Onizuka, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  第４０回国際核酸化学シンポジウム
- Place of Presentation
  Kanagawa University, Japan
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 遷移金属カチオン活性化機構をもつ機能性人工核酸を用いた部位特異的特異的RNA修飾化学修飾反応2013
- Author(s)
  實崎大地、鬼塚和光、西本篤史、谷口陽祐、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー第８回年会
- Place of Presentation
  東京　東京医科歯科大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] ODN containing functionalized thioguanosine: Useful tools for selective guanosine RNA targeting2013
- Author(s)
  Jan Barta, Daichi Jitsuzaki, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  第４０回国際核酸化学シンポジウム
- Place of Presentation
  Kanagawa University, Japan
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] CpGアイランドを標的とした人工核酸の開発2013
- Author(s)
  松枝望、谷口陽祐、佐々木茂貴
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎（長崎国際大学）
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Design, synthesis, and properties of 8-halogenated-7-deaza-2’-deoxyguanosine as analogues of 8-oxo-2’-deoxyguanosine2013
- Author(s)
  尹貽貞、谷口陽祐、佐々木茂貴
- Organizer
  第５０回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 8-oxodGに対する塩基選択性の向上を目指したAdap誘導体の開発2013
- Author(s)
  菊川誉也、谷口陽祐、深堀慶太郎、佐々木茂貴
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎（長崎国際大学）
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 8-oxo-clampを基本骨格とする水中での8-オキソグアノシン特異的検出に向けたアプローチ2013
- Author(s)
  渕靖史、李志春、佐々木茂貴
- Organizer
  第７回バイオ関連化学シンポジウム
- Place of Presentation
  名古屋　名古屋大学
- Data Source
  KAKENHI-PROJECT-24659008
[Presentation] ピリミジン型機能性人工核酸を用いた金属カチオン応答性アデニン特異的RNA修飾法の開発2013
- Author(s)
  大城郁也、實崎大地、西本篤史、鬼塚和光、谷口陽祐、佐々木茂貴
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎（長崎国際大学）
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Optimization of fluorescence property of the 8-oxoG-clamp derivative for better selectivity for 8-oxo-2'-deoxyguanosine2013
- Author(s)
  Yasufumi Fuchi, Yohei Koga, Shigeki Sasaki
- Organizer
  The 23rd FRENCH-JAPANESE SYMPOSIUM on Medicinal and Fine Chemistry
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-24659008
[Presentation] An antiproliferative eff ect by targeting oncogene with antigene oligonucleotides containing WNA-βT in an antiparallel triplex formation2013
- Author(s)
  Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  第４０回国際核酸化学シンポジウム
- Place of Presentation
  Kanagawa University, Japan
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 繰り返し配列を含むDNAに対して協奏的に集積する低分子化合物の合成および評価2013
- Author(s)
  江田裕則、John BRAZIER、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー第８回年会
- Place of Presentation
  東京　東京医科歯科大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 二種の金属錯体を形成部位をもつアントラセノン誘導体の合成とDNAリピート配列への多協同的結合の検討2013
- Author(s)
  村瀬裕貴、佐々木茂貴
- Organizer
  第３９回反応と合成の進歩シンポジウム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] T-Viny1 Derivative as an 4 Efficient and Selective Cross-Linking Agent for RNA and duplex DNA2013
- Author(s)
  Shigeki Sasaki, Nishimoto A., Jitsuzaki D., Onizuka K., Yosuke Taniguchi, Nahatsugi F.
- Organizer
  9th Annual Meeting of the OLIGONYCLEOTIDE Therapeutics Society
- Place of Presentation
  Napoli, Italia
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Functionality Transfer for the Pinpoint Selective Modefication of RNA Inducible Reactivity Mediated by Chelate Formation with Metal Cation2013
- Author(s)
  Shigeki Sasaki, Yosuke Taniguchi, D. Jitsuzaki, K.Onizuka, A.Nishimoto, I.Oshiro, A.Shibata
- Organizer
  The 5th Asian Aeden Confernce
- Place of Presentation
  Nagoya City University
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] エクソン-イントロン接合部に重複したマイクロ RNA の発現2013
- Author(s)
  柴田篤志、佐々木茂貴
- Organizer
  第２３回アンチセンスシンポジウム
- Place of Presentation
  徳島（徳島大学大塚講堂）
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 膵β細胞株MIN6細胞を標的としたDDS, β-MENDの構築および核酸導入・機能発現の検証2013
- Author(s)
  田端麻衣、山田勇磨、安崎友香理、野村政壽、柴田篤志、佐々木茂樹、原島秀吉
- Organizer
  日本薬学会北海道支部第140回例会
- Place of Presentation
  札幌(札幌コンベンションセンター)
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] N-(Guanidinoethyl)-2'-deoxy-5-methylisocytidine exhibits selective recognition of the CG inversion site for the formation of anti-parallel triplex DNA2013
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi, and Shigeki Sasaki
- Organizer
  ＡＣＭＳ２０１３
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] CG塩基対を選択的に認識するN2-修飾イソシチジン誘導体の合成と3本鎖形成能の評価2013
- Author(s)
  岡村秀紀、谷口陽祐、佐々木茂貴
- Organizer
  第４３回複素環化学討論会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] DNAのB-Z平衡と[5]ヘリセンリガンドの不斉平衡に基づく動的不斉誘起の検討2013
- Author(s)
  川良健祐、辻厳一郎、佐々木茂貴
- Organizer
  第４３回複素環化学討論会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 二種の金属錯体形成部位をもつ分子によるDNAリピート配列への協同的結合の検討2013
- Author(s)
  村瀬裕貴、佐々木茂貴
- Organizer
  第７回バイオ関連化学シンポジウム
- Place of Presentation
  名古屋　名古屋大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] ＤＮＡ上の繰り返し配列に対して協奏的に自己集積する低分子化合物の開発2013
- Author(s)
  江田裕則、John BRAZIER、佐々木茂貴
- Organizer
  第５０回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Synthesis and evaluation of novel Hoechst derivatives for cooperative binding to repeating DNA sequences2013
- Author(s)
  Hironori Koda, John Brazier, Shigeki Sasaki
- Organizer
  第４０回国際核酸化学シンポジウム
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 金属応答性ピリミジン型機能性人工核酸を用いたアデニン特異的RNA修飾法の開発2013
- Author(s)
  大城郁也、實崎大地、西本篤史、鬼塚和光、谷口陽祐、佐々木茂貴
- Organizer
  第３９回反応と合成の進歩シンポジウム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Molecular design and synthesis for selective recognition and reaction of DNA and RNA2013
- Author(s)
  Shigeki Sasaki
- Organizer
  Report of Lectureship in Hong Kong
- Place of Presentation
  The Chinese University of Hong Kong
- Invited
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] An efficient method for RNA modification with high sequence and base selectivity using non-natural efficient　method　for　RNA　modification　with　high　sequence　and base　selectivity　using　non-natural　functional ODN2013
- Author(s)
  Shigeki Sasaki, Daichi Jitsuzaki, Atsushi Nishimoto, Kazumitsu Onizuka, Fumi Nagatsugi, Yosuke Taniguchi
- Organizer
  Gordon Research Confernces
- Place of Presentation
  Salve Regina University(USA)
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Genome-targeting chemistry for a new therapeutic approach, Frontiers in Medicinal Chemistry2013
- Author(s)
  Sasaki, S
- Organizer
  Joint German-Swiss Meeting on Medicinal Chemistry
- Place of Presentation
  Munich
- Year and Date
  2013-03-20
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 遷移金属カチオンにより活性化する部位特異的RNA化学修飾反応の開発と反応機構の解析2013
- Author(s)
  實崎大地、鬼塚和光、西本篤史、谷口陽祐、佐々木茂貴
- Organizer
  第５０回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 2-aminoAdapによるDNA中の8-oxodG検出法の開発2013
- Author(s)
  谷口陽祐、深堀慶太郎、古賀洋平、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー第８回年会
- Place of Presentation
  東京　東京医科歯科大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 脱塩基部位を特異的に切断する核酸- ポリアミン結合体の特性2013
- Author(s)
  阿部由紀子，山口莉慧，佐々木茂貴
- Organizer
  第３１回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島（広島市アステールプラザ）
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] ８-ニトログアノシンに対する反応を利用した特異的捕捉分子の開発2013
- Author(s)
  渕靖史、佐々木茂貴
- Organizer
  第３９回反応と合成の進歩シンポジウム
- Place of Presentation
  福岡、九州大学
- Data Source
  KAKENHI-PROJECT-24659008
[Presentation] Site-Specific Chemical Modification of RNA and Impact on its Function2013
- Author(s)
  Shigeki Sasaki
- Organizer
  Asia 3 Roundtable of Nucleic Acids 2013, Japan
- Place of Presentation
  Portapia Hotel, Kobe
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Synthesesand Evaluation of Anti-parallel Triplex Formation of 1’-Phenyl-2’-ThymineNucleoside Analogues for the Application to the Antigene Strategy2013
- Author(s)
  Yosuke Taniguchi,Akira Tomizaki, Hidenori Okamura, Syohei Misumi, Tomoko Takaki, Naoto Ishibashi and Shigeki Sasaki
- Organizer
  ＡＩＭＥＣＳ２０１３
- Place of Presentation
  台湾
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] CG 塩基対を選択的に認識可能なN- グアニジノエチルイソシチジンの合成と3 本鎖DNA 形成能の評価2013
- Author(s)
  岡村秀紀、谷口陽祐、佐々木茂貴
- Organizer
  第５０回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] N²-Modified Isocytidine Derivatives for Selective CG Base Pair Recognition in the Triplex DNA2013
- Author(s)
  Hedenori Okamura, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  3rd ACP Junior Symposium
- Place of Presentation
  Chiba
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 繰り返し領域を含む二本鎖DNAに対して協奏的に集積する低分子化合物の合成および評価2013
- Author(s)
  江田裕則、JohnBrazier、佐々木茂貴
- Organizer
  第７回バイオ関連化学シンポジウム
- Place of Presentation
  名古屋　名古屋大学
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] An Efficient Reaction for Pinpoint Modification of RNA Promoted by Proximity Effect via Transition Metal Complex2013
- Author(s)
  Shigeki Sasaki, Daichi Jitsuzaki, Onizuka Kazumitsu, Nishimoto Atsushi, Shibata Atsushi, Oshiro Ikuya, Yosuke Taniguchi
- Organizer
  ICCEPOCA-8/NICCEOCA-4
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 金属錯体形成によりRNAを部位特異的に化学修飾する機能性人工核酸の開発2013
- Author(s)
  實崎大地、鬼塚和光、西本篤史、谷口陽祐、佐々木茂貴
- Organizer
  第２３回アンチセンスシンポジウム
- Place of Presentation
  徳島（徳島大学大塚講堂）
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 2'位メトキシピリミジン型クロスリンク核酸の開発と評価2013
- Author(s)
  秋島広佑、西本篤史、實崎大地、谷口陽祐、永次史、佐々木茂貴
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎（長崎国際大学）
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Inhibition of the cell proliferation using triplex forming oligonucleotides containing a W-shaped Nucleoside analogues2013
- Author(s)
  Yosuke Taniguchi and Shigeki Sasaki
- Organizer
  ＡＣＭＳ２０１３
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Genome-targeting chemistru for a new therapeutic approach2013
- Author(s)
  Shigeki Sasaki
- Organizer
  Frontiers in Medicinal Chemistry
- Place of Presentation
  Ludwig-Maximilians Universital Munchen
- Invited
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 生命への合成化学者のチャレンジ：ゲノム標的化学の提案2012
- Author(s)
  佐々木茂貴
- Organizer
  第47回　天然物化学談話会
- Place of Presentation
  阿蘇プラザホテル
- Invited
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Molecular design of non-natural nucleosides for selective recognition and reaction with DNA and RNA2012
- Author(s)
  Sasaki, S
- Organizer
  13th Tetrahedron Symposium
- Place of Presentation
  Amsterdam
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Synthesis and triplex DNA forming evaluation of 2'-deoxyisocytidine derivatives with two hydrogen-bonding sites2012
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi,Shigeki Sasaki
- Organizer
  2nd Junior ICCEOCA(Asian Core Program)
- Place of Presentation
  Ｕｎｉｖｅｒｓｉｔｙ　ｏｆ　Ｍａｌａｙａ　Ｋuａｌａ　Ｌｕｍｐｕｒ
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] A New Tool for Site-specific Cheminal Modefication RNA and its Biological Application2012
- Author(s)
  Shigeki Sasaki
- Organizer
  2012 The 4th Korean Nucleic Acids Sociery(KNAS)International Symposium
- Place of Presentation
  Korea
- Invited
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] An Application of the Functionality Transfer Reaction for the Selective and Sensitive Detection of O⁶-Methy1-2'-Deoxyguanosine in DNA2012
- Author(s)
  Shigeki Sasaki
- Organizer
  XX International Round Table on Nucleosides Nucleotides and Nucleic Acids
- Place of Presentation
  Canada
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Molecular design of non-natural nucleosides for selective recognition and reaction with DNA and RNA2012
- Author(s)
  Shigeki 　Sasaki
- Organizer
  13th Tetrahefron Symposium (ASIA EDITION)
- Place of Presentation
  Howard Civil International Centre, Taipei.
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Triplex formation and an efficient DNA strand displacement reaction with the W-shaped uncleoside analogs( WNA-BT)2012
- Author(s)
  Shigeki Sasaki
- Organizer
  Asian 3　Roundtable on Nucleic Scids　２０１２　KOREA
- Place of Presentation
  Korea
- Invited
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] ortho-Methyl Substituted W-Shaped Nucleoside Analog(WNA-βT) Accelerates the DNA Strand Displacement Reaction2012
- Author(s)
  Shigeki Sasaki
- Organizer
  ICCEPOCA-7/NICCEOCA-3
- Place of Presentation
  Nanyang Technologinal University
- Invited
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Molecular design of non-natural nucleosides for selective recognition and reaction with DNA and RNA2012
- Author(s)
  Shigeki Sasaki
- Organizer
  13th Tetrahefron Symposium
- Place of Presentation
  Holland
- Invited
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Non-natural Nucleoside Analogs for Recognition of 8-Oxo-2'-deoxyguano- sine2012
- Author(s)
  Sasaki, S
- Organizer
  1st International Symposium on Polymer Ecomaterials (PEM 2012)
- Place of Presentation
  Changchun, China
- Year and Date
  2012-08-21
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] (AT)n配列特異的にB→Z遷移を誘起するポルフィリン誘導体の開発2012
- Author(s)
  佐々木英哲, et al
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Non-natural nucleoside analogs for the formation of the stable triplex DNA and its application to inhibition of gene expression2012
- Author(s)
  Shigeki Sasaki
- Organizer
  10th France-Japan DDS Symposium
- Place of Presentation
  France
- Invited
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] A New Tool for Site-Specific Modification of RNA2011
- Author(s)
  Sasaki, S
- Organizer
  Pharmaceutical Sciences World Congress
- Place of Presentation
  New Orleans, USA
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] ゲノム標的化学:DNAおよびRNAに対してピンポイント選択的認識および反応性分子の開発2011
- Author(s)
  佐々木茂貴
- Organizer
  第5回薬学研究フォーラムin東京
- Place of Presentation
  日本薬学会長井記念ホール(東京都)(依頼講演)
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Non-natural Nucleoside Analogs for Recognition of 8-Oxo-2'-deoxyguanosine2011
- Author(s)
  Shigeki Sasaki, et al
- Organizer
  6th Cambridge Symposium on Nucleic Acids Chemistry and Biology
- Place of Presentation
  Queens' College Cambridge, UK(selected oral)
- Year and Date
  2011-09-05
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] A NEW TOOL FOR SITE-SPECIFIC CHEMICAL MODIFICATION OF RNA2011
- Author(s)
  Shigeki Sasaki, et al
- Organizer
  7th Annual Meeting of the Oligonucleo-tide Therapeutics Society
- Place of Presentation
  The Royal Library Copenhagen, Denmark
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 核酸医薬への期待と遺伝子標的化学のアプローチ2011
- Author(s)
  佐々木茂貴
- Organizer
  創薬懇話会2011
- Place of Presentation
  瀬戸内マリンホテル(岡山県)(招待講演)
- Year and Date
  2011-07-06
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] A Single Nucleotide Modification of RNA and DNA by Functionality Transfer Reaction2011
- Author(s)
  Shigeki Sasaki
- Organizer
  AIMECS11(第8AFMC国際医薬化学シンポジウム)
- Place of Presentation
  京王プラザホテル東京
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 光照射によりB-Z構造遷移能を制御する低分子リガンドの開発2011
- Author(s)
  辻厳一郎、佐々木茂貴
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  筑波国際会議場、茨城県
- Data Source
  KAKENHI-PROJECT-22659004
[Presentation] 光照射によりB-Z-DNA構造変換能を変化させる低分子化合物の開発2011
- Author(s)
  辻厳一郎、佐々木茂貴
- Organizer
  有機合成化学協会九州山口支部第23回若手研究者のためのセミナー
- Place of Presentation
  九州大学薬学部、福岡県
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PROJECT-22659004
[Presentation] 光照射によりBZ誘起能を制御する低分子化合物の開発2011
- Author(s)
  辻厳一郎、佐々木茂貴
- Organizer
  第6回ケミカルバイオロジー年会
- Place of Presentation
  東京工業大学、東京都
- Data Source
  KAKENHI-PROJECT-22659004
[Presentation] 光照射によりBZ遷移能を制御する低分子化合物の開発2011
- Author(s)
  辻厳一郎、川上京子、佐々木茂貴
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡県
- Data Source
  KAKENHI-PROJECT-22659004
[Presentation] New Recognition Molecules for 8-Oxo-2'-Deoxyguanosine2011
- Author(s)
  Shigeki Sasaki
- Organizer
  A3RONA 2011 Wuhan
- Place of Presentation
  Wuhan Hongyi Hotel(invited)
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] 光応答性リガンドによるDNA2本鎖キラリティーの制御2011
- Author(s)
  辻厳一郎,佐々木茂貴
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡大学薬学部、福岡市
- Data Source
  KAKENHI-PROJECT-22659004
[Presentation] BZ遷i移能を有するキラルビスアリールリガンドの開発2011
- Author(s)
  辻厳一郎、川上京子、佐々木茂貴
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-22659004
[Presentation] Selective Fluorescent Probe for 8-Oxoguanosine2011
- Author(s)
  Shigeki Sasaki, et al
- Organizer
  22nd French-Japanese Symposium of Medicinal and Fine Chemistry
- Place of Presentation
  Rouen, France(組織委員)
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Adenosine-1,3-Diazaphenoxazine Nucleoside Analog for Recognition of 8-Oxo-2'-deoxyguanosine in DNA2011
- Author(s)
  Shigeki Sasaki
- Organizer
  ICCEOCA-6NICCEOCA-2 2011
- Place of Presentation
  The Chinese University of Hong Kong(組織委員)
- Year and Date
  2011-12-12
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] A New Biotechnology for Site-Specific Chemical Modification of RNA2011
- Author(s)
  S.Sasaki, et al
- Organizer
  International Conference on Biomaterial Science2011
- Place of Presentation
  Tsukuba, Japan
- Year and Date
  2011-03-15
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Artificially Designed Functional Oligonucleotides For Chemical Modification of DNA and RNA2010
- Author(s)
  S.Sasaki, et al
- Organizer
  Asian Roundtable on Nucleic Acids
- Place of Presentation
  ホテル日航関西空港
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] A New Biological Tool for Nucleobase and Site-Specific Modification of RNA by Utilizing Functionality Transfer Reaction (FTR)2010
- Author(s)
  S.Sasaki, et al
- Organizer
  9th France-Japan DDS Symposium
- Place of Presentation
  KKRホテル、熊本市
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] DNA高次構造認識分子の開発を目指したポリフィリン誘導体の合成2010
- Author(s)
  佐々木英哲
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山コンベンションセンター他
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] A New Biological Tool for Nucleobase and Site-Specific Modification of RNA by Utilizing Functionality Transfer Reaction(FTR)2010
- Author(s)
  shigeki Sasaki, et al
- Organizer
  9th France-Japan DDS Symposium
- Place of Presentation
  KKRホテル熊本
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] BZ遷移能を有するビスアリール化合物におけるBZ構造変換メカニズムの検討2010
- Author(s)
  辻厳一郎、川上京子、土井一生、佐々木茂貴
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  大阪大学豊中キャンパス、大阪府
- Data Source
  KAKENHI-PROJECT-22659004
[Presentation] B-ZDNA構造遷移を誘起するキラルビスアリール化合物の開発2010
- Author(s)
  川上京子、辻厳一郎、土井一生、佐々木茂貴
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎大学文教キャンパス、長崎県
- Data Source
  KAKENHI-PROJECT-22659004
[Presentation] A New Tool for Site-Specific Modification of RNA2010
- Author(s)
  S.Sasaki, et al
- Organizer
  Pharmaceutical Sciences World Congress 2010
- Place of Presentation
  New Orleans, USA
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] インテリジェント人工核酸による配列特異的なRNA化学修飾と機能制御2010
- Author(s)
  佐々木茂貴
- Organizer
  第47回化学関連支部九州合同大会
- Place of Presentation
  北九州国際会議場、北九州市
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Development of the diaryl-spermine conjugate as an effective B-Z inducer2010
- Author(s)
  G. Tsuji, I. Doi, K. Kawakami, S. Sasaki
- Organizer
  International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-22659004
[Presentation] RNAの部位特異的科学修飾のための人工核酸ツールの開発と応用2010
- Author(s)
  佐々木茂貴
- Organizer
  日本化学会第90春季年会(2010)
- Place of Presentation
  近幾大学本部キャンパス
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Nucleobase and Site Specific Chemical Modification of RNA2010
- Author(s)
  S.Sasaki, et al
- Organizer
  Telluride Science Conference on Nucleic Acid Topics
- Place of Presentation
  Telluride Intermediate School, Colorado, USA
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Functionality Transfer Reaction(FTR)as a PowerfulTool for Site-Specific Modefication of RNA2010
- Author(s)
  Shigeki Sasaki, et al
- Organizer
  ICCEOC-5
- Place of Presentation
  Taiwan
- Year and Date
  2010-11-09
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] BZ遷移能を有する新規ビスアリール誘導体の開発2010
- Author(s)
  辻厳一郎、土井一生、川上京子、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  慶応義塾大学日吉キャンパス、神奈川県
- Data Source
  KAKENHI-PROJECT-22659004
[Presentation] Synthesis and analysis of spermine-bisaryl conjugates as the new ligand for the B to Z-DNA transition2010
- Author(s)
  K. Kawakami, I. Doi, G. Tsuji, S. Sasaki
- Organizer
  he 37th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-22659004
[Presentation] INTELLIGENT FUNCTIONS FOR NEW APPROACH OF THERAPEUTIC OLIG ONUCLEOTIDES2009
- Author(s)
  Shigeki Sasak
- Organizer
  遺伝子・デリバリー研究会第9回シンポジウム
- Place of Presentation
  大阪大学コンベンションセンター
- Year and Date
  2009-07-10
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] インテリジェント核酸医薬へのチャレンジ2009
- Author(s)
  佐々木茂貴
- Organizer
  -新適塾-「未来創薬への誘い」第7回会合
- Place of Presentation
  (財)千里ライフサイエンス振興財団(大阪府)
- Year and Date
  2009-07-15
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] A New Chemical Probe for Site-Specific Modification of RNA,2009
- Author(s)
  Shigeki Sasaki
- Organizer
  13th Asian Chemical Congress
- Place of Presentation
  中国国際コンベンションセンター
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Design of Specific Reaction to DNA and RNA for Regulation of Gene Expression-New Functionality Transfer Reaction for Site-selective Modification of RNA2009
- Author(s)
  S. Sasaki
- Organizer
  The 3rd International Conference on Cutting-Edge Organic Chemistry in Asia under Asian Core Program
- Place of Presentation
  杭州市、中国
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 選択的化学反応による遺伝子改変へのアプローチ2009
- Author(s)
  佐々木茂貴
- Organizer
  第4回理研「バイオ医工学シンポジウム」
- Place of Presentation
  独立行政法人理化学研究所鈴木梅太郎ホール
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 選択的化学反応による遺伝子改変へのアプローチ2009
- Author(s)
  佐々木茂貴
- Organizer
  第4回バイオ医工学シンポジウム
- Place of Presentation
  理化学研究所(和光市)
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] DNA高次構造認識分子の開発を目指したポルフィリン誘導体の合成検討2009
- Author(s)
  佐々木英哲
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] DNA高次構造認識分子の開発を目指したポルフィリン誘導体の合成2009
- Author(s)
  佐々木英哲
- Organizer
  第26回日本薬学会九州支部大会
- Place of Presentation
  九州大学薬学部(福岡市)
- Data Source
  KAKENHI-PROJECT-21229002
[Presentation] Design of Specific Reaction to DNA and RNA for Regulation of Gene Expression-New Functionality Transfer Reaction for Site-selective Modification of RNA2008
- Author(s)
  S. Sasaki
- Organizer
  The 3rd International Conference on Cutting-Edge Organic Chemistry in Asia under Asian Core Program
- Place of Presentation
  Lis Ying Hotel(China)
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] アンチセンスの機能拡張を目指したインテリジェント人工核酸2008
- Author(s)
  佐々木茂貴
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜大学薬学部記念会館(岐阜県)
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 遺伝子発現の制御を目指した三重鎖形成人工塩基の新展開2008
- Author(s)
  佐々木茂貴
- Organizer
  第24回日本DDS学会学術集会
- Place of Presentation
  東京六本木ヒルズ
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] アンチセンスの機能拡張を目指したインテリジェント人工核酸2008
- Author(s)
  佐々木茂貴
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜大学医学部記念会館
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 酸化損傷塩基8-オキソグアノシン特異的蛍光プローブの開発2008
- Author(s)
  佐々木茂貴、中川治、小野沙弥香、李志春、辻本朗、古賀洋平
- Organizer
  第47回電子スピンサイエンス学会年会
- Place of Presentation
  九州大学医学部百年講堂
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 酸化損傷塩基8-オキソグアノシン特異的蛍光プローブの開発2008
- Author(s)
  佐々木茂貴
- Organizer
  第47回電子スピンサイエンス学会年
- Place of Presentation
  九州大学医学部百年講堂
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 長い繰り返し配列を持つDNA上にCu^<2+>を介して集積する分子の開発2008
- Author(s)
 大西一平, J. Brazier, 佐々木茂貴
- Organizer
 第25回日本薬学会九州支部大会
- Place of Presentation
 九州保健福祉大学(延岡市)
- Year and Date
 2008-12-07
- Data Source
 KAKENHI-PROJECT-20659003
[Presentation] New Functionality Transfer Reaction for Site-Selective Modification of RNA and DNA2008
- Author(s)
  S. Sasaki
- Organizer
  8th France-Japan DDS Symposium
- Place of Presentation
  Cannes, France
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 遺伝子特異的人工核酸のデリバリーシステムを用いた細胞内反応への展開-化学反応による遺伝子修飾および修復を目指して2008
- Author(s)
  佐々木茂貴、永次史、井本修平、谷口陽祐、鬼塚和光
- Organizer
  第57回高分子討論会
- Place of Presentation
  大阪市立大学(大阪市)
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 遺伝子特異的人工核酸のデリバリーシステムを用いた細胞内反応への展開-化学反応による遺伝子修飾および修復を目指して2008
- Author(s)
  佐々木茂貴
- Organizer
  第57回高分子討論会
- Place of Presentation
  大阪市立大学
- Year and Date
  2008-09-26
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] Molecular design for detection of RNA transcripts, higher order DNA structures and tiny changes of nucleobases.2008
- Author(s)
  Shigeki Sasaki
- Organizer
  BMB2008
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 遺伝子発現の制御を目指した三重鎖形成人工塩基の新展開2008
- Author(s)
  佐々木茂貴
- Organizer
  第24回日本DDS 学会学術集会
- Place of Presentation
  六本木ヒルズ(東京都)
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] Design of S-vinlyated 6-thioguanosine as a specific modifier of cytidine2008
- Author(s)
  K. Onizuka, Y.Taniguchi, S. Sasaki
- Organizer
  14th Symposium on Chemistry of Nucleic Acid Components
- Place of Presentation
  Cesky Krumlov, Czech
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] DNA高次構造認識分子の開発を目指したポルフィリン誘導体の合成検討2008
- Author(s)
  佐々木英哲
- Organizer
  第34回反応と合成の進歩シンポジウム
- Place of Presentation
  京都テルサ
- Year and Date
  2008-11-04
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] DNAの高次構造の認識をめざした新規リガンドの開発2007
- Author(s)
  佐々木英哲、John Brazier、大西一平、渡邊詩乃、佐々木茂貴
- Organizer
  第24回九州支部大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] DNAの高次構造の認識をめざした新規リガンドの開発2007
- Author(s)
  佐々木英哲、John Brazier、大西一平、渡辺詩乃、佐々木茂貴
- Organizer
  第24回九州支部大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18659004
[Presentation] 反応性向上を目指した新規nitroG-Grasp誘導体の合成と捕捉反応評価
- Author(s)
  渕　靖史、大林秀都、佐々木茂貴
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] Synthesis and evaluation of capture molecules for 8-thioguanosine
- Author(s)
  Hideto Obayashi, Yasufumi Fuchi, Shigeki Sasaki
- Organizer
  41st International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  北九州
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] 共有結合捕捉能をもつ8-thioguanosine認識分子の開発
- Author(s)
  大林秀都、渕　靖史、佐々木茂貴
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] 生体内シグナル伝達に関与する8位酸化グアノシン選択的捕捉モデル分子の開発
- Author(s)
  渕　靖史、大林秀都、佐々木茂貴
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸
- Year and Date
  2015-11-26 – 2015-11-28
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] 8-thioGを特異的に捕捉する低分子プローブの開発
- Author(s)
  大林秀都、渕　靖史、佐々木茂貴
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-26670004
[Presentation] New perspectives for non-enzymatic 2’-deoxyxytidine deamination
- Author(s)
  Barta Jan, Taniguchi Yosuke, Sasaki Sigeki
- Organizer
  41st International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kitakyushu
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-12F02750
[Presentation] 水素結合錯体を介した効率的な8-ニトログアノシン補足反応分子の開発
- Author(s)
  渕　靖史、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー学会　第9回年会
- Place of Presentation
  大阪
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-26670004

1. TSUZUKI Teruhisa (40155429)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. NAGATSUGI Fumi (90208025)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
3. NAKATSU Yoshimichi (00207820)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TANIGUCHI Yosuke (00452714)

# of Collaborated Projects: 2 results

# of Collaborated Products: 41 results
5. SEKIMIZU Kazuhisa (90126095)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MIKI Takeyoshi (40037586)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KOGA Kenji (10012600)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. FUCHI Yasufumi (40748795)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
9. 村瀬裕貴 (10814486)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
10. BARTA Jan

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. NAKAGAWA Osamu (90380691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. HARASHIMA Hideyoshi (00183567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. HYOUDOU Mamoru (30548186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SHINDO Mitsuru (40226345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NOMURA Masatoshi (30315080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. MAEDA Minoru (70101178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TORIGOE Hidetaka (80227678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. OHISHI Hirofumi (00211095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KURA Shinobu (90037391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAMURA Katsumasa (20284507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MORITA Takashi (70150349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TOMIOKA Kiyoshi (50114575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. Nagasaki Yukio (90198309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 早川浩 (70150422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 原寿郎 (40150445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 井原健二 (80294932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 吉冨徹 (20585799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 丸山達生 (30346811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 案浦健 (90407239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 富田勉 (30772488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 池田豊 (70425734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 塩田倫史 (00374950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
33. 山田耕平 (40583232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 吉田達貞 (80527557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 西奥剛 (90435115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. KOBAYAKAWA Takahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. TAKIGAWA Tetsuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. OBAYASHI Hideto

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
39. FUKUDA Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
40. 酒井康成

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 早川敬博

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 唐沢悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 鬼塚和光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 阿部由紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SASAKI Shigeki 佐々木 茂貴

佐々木 茂喜 ササキ シゲキ

Research Projects

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Co-Researchers

Basic research into nucleic acid drugs that induce readthrough by chemically modifying the adenosine at the premature termination codonPrincipal Investigator

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Development of small molecule drugs for fragile X syndrome based on ligands that cooperatively accumulate on the CGG repeats.Principal Investigator

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Molecular design of innovative drugs based on molecular assembly

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Development of the artificial oligonucleotides for the RNA pinpoint modification and the application to RNA editingPrincipal Investigator

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Development of small molecular ligands for simultaneous binding to the multiple sites of DNAPrincipal Investigator

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Chemically reactive oligonucleotides for site-specific modification of RNA and artificial RNA editingPrincipal Investigator

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Development of capture probes for the signaling nucleotide molecules in cells

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Development of recognition molecules for 8-oxidized guanosine derivativesPrincipal Investigator

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Development of the selective capture molecule for 8-nitroguanosinePrincipal Investigator

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官能基転移反応によるＲＮＡの化学修飾法の開発Principal Investigator

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Photochromic DNA Binding Ligands for B and Z-DNA InterconversionPrincipal Investigator

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Study on the innovative molecular-targeting medicine based on the nano-DDS encapsulating intelligent artificial oligonucleotidesPrincipal Investigator

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異常に長い繰り返し配列のDNA上に金属イオンを解して自己集積する分子の開発Principal Investigator

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Project Period (FY)

SASAKI Shigeki 佐々木茂貴

佐々木茂喜ササキシゲキ